find a leader in applying directed evolution

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Find A Leader in Applying Directed Evolution Prepared and Compiled by Creative Biomart

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Page 1: Find a leader in applying directed evolution

Find A Leader in Applying Directed Evolution

Prepared and Compiled by Creative Biomart

Page 2: Find a leader in applying directed evolution

Directed Evolution

Directed evolution is a method used in protein engineering that mimics the process of natural selection to evolve proteins ornucleic acids toward a user-defined goal.

Page 3: Find a leader in applying directed evolution

Technical Solution • In vitro molecular evolution strategies are

widely regarded as the most efficient methods for creating proteins and regulatory sequences with improved or novel properties. Creative Biomart GenePowerTM Directed Evolution services cover a variety of different approaches for creating genetic variants. Paired with appropriate screening methods, our directed evolution technologies can create the genetic diversity you need to obtain proteins with the characteristics you need.

Page 4: Find a leader in applying directed evolution

Advantage

•Most service offerings do not require DNA template—DNA is synthesized from your sequence information. •Complete control over every important feature of the library—Create rational diversity where it is likely to have the most impact. •Significantly reduced screening effort compared to conventional mutagenesis methods. •Generate variants that cannot be created using conventional methods. •Maximum sequence integrity in unmutated regions, maximum variation where you want it, and maximum insert size. •Improved likelihood of obtaining useful variants.

Page 5: Find a leader in applying directed evolution

About Creative Biomart

Creative Biomart is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics.

Page 6: Find a leader in applying directed evolution

Contact

• Creative Biomart

• http://www.creativebiomart.net/Directed-Evolution.htm

• 45-16 Ramsey Road, Shirley, NY 11967, USA TEL: 1-631-559-9269 EMAIL: [email protected]

• St John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK TEL: 44-207-048-3343

Page 7: Find a leader in applying directed evolution

Thank You

We understand the importance of convenient and easy-to-use systems for high level expression and sample purification. We invite you to review our growing range of expression systems resulting from our experience in cloning, overexpression and purification.