xls file · web viewa1-l1100-03 a2-l1100-03 h11-l1100-03 h6-l1100-03 e11-l1100-03 e8-l1100-03...

Inhibitor Screening Library (96-well)

Product Details:Formulation A collection of 1159 inhibitors supplied as lyophilized powder or pre-dissolved DMSO solutions.

Stability2 weeks | 4°C | in DMSO

Shipping Blue ice

Packaged under inertYes

Plate layout: L1100-01

1 2 3 4 5

a ABT-737 Linifanib (ABT-869) ABT-888 (Veliparib) Axitinib

b Bosutinib (SKI-606) Dovitinib (TKI-258) CI-1033 (Canertinib)

c Nilotinib (AMN-107) NVP-AEW541

d Trichostatin A (TSA)

e Olaparib (AZD2281) Nutlin-3 Masitinib (AB1010)

f HA14-1 ZSTK474 SB 216763 SB 203580 SB 202190

g Iniparib (BSI-201) NVP-ADW742 PCI-24781 Linsitinib (OSI-906) KU-55933

h MLN8054 U0126-EtOH ZM-447439 GDC-0879


1 2 3 4 5

a SGX-523 GSK690693 JNJ-38877605

b SRT1720 YM155 INO-1001

For more information on Selleck library service, please contact us via +1-832-582-8158 or [email protected]

Container (Optional) 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

3 months | ﹣20°C | in DMSO

6 months | ﹣80°C | in DMSO

ABT-263 (Navitoclax)

Bortezomib (Velcade)

Cediranib (AZD2171)

Lapatinib Ditosylate (Tykerb)

Lenalidomide (Revlimid)

Motesanib Diphosphate (AMG-706)

Sunitinib Malate (Sutent)

Tandutinib (MLN518)

Temsirolimus (Torisel)

Vandetanib (Zactima)

BMS-599626 (AC480)

Obatoclax mesylate (GX15-070)

Vatalanib 2HCl (PTK787)

Foretinib (GSK1363089, XL880)

Odanacatib (MK 0822)

Mocetinostat (MGCD0103)

Abiraterone (CB-7598)

c AG-490 Ivacaftor (VX-770)

d SNS-314 Mesylate MK-8245

e CP-724714 TGX-221 WZ3146 CYC116

f WZ8040 XAV-939 ENMD-2076 Danoprevir Ritonavir

g Thalidomide CUDC-101 TAK-700 (Orteronel) Exemestane

h PIK-75 Bisoprolol Tivozanib (AV-951)


1 2 3 4 5

a Clofarabine YM201636 OSI-930

b Topotecan HCl 2-Methoxyestradiol AG-1024 Letrozole

c Dienogest Rufinamide (Banzel) Posaconazole Prasugrel (Effient)

d IC-87114 BX-795 BX-912 Amisulpride

e Celastrol Cetirizine DiHCl Cilnidipine Cilostazol Epothilone A

f Ki16425 AMG-208 Costunolide Dexamethasone Doxazosin mesylate

g Gabapentin HCl Galanthamine HBr Genistein Glimepiride

h Losartan potassium GSK1059615 MGCD-265 Ki8751


1 2 3 4 5

a Isotretinoin Lopinavir (ABT-378) Mianserin HCl Minoxidil

b Oxcarbazepine Pelitinib (EKB-569) Resveratrol Stavudine

17-AAG (Tanespimycin)

17-DMAG HCl (Alvespimycin)

SNS-032 (BMS-387032)

Roscovitine (Seliciclib, CYC202)

NSC 74859 (S3I-201)

Capecitabine (Xeloda)

Valproic acid sodium salt (Sodium valproate)

Raltitrexed (Tomudex)

Doxorubicin (Adriamycin)

Adrucil (Fluorouracil)

Clafen (Cyclophosphamide)

Dacarbazine (DTIC-Dome)

Fludarabine Phosphate (Fludara)

MDV3100 (Enzalutamide)

Vemurafenib (PLX4032)

Fluvoxamine maleate

Rigosertib (ON-01910)

Ruxolitinib (INCB018424)

Rocuronium bromide

c Staurosporine Droxinostat Ranolazine 2HCl Repaglinide Rolipram

d Venlafaxine Voriconazole Zileuton Aurora A Inhibitor I

e SP600125 Ofloxacin (Floxin) Moxifloxacin HCl Alfacalcidol TSU-68 (SU6668)

f MC1568 HMN-214

g NVP-BEP800 Dyphylline (Dilor)

h AT7519 MK-1775 Quizartinib (AC220) LY2811376


1 2 3 4 5

a DMXAA (ASA404) Telaprevir (VX-950) EX 527 AM-1241

b KRN 633 AT7867 BMS 777607 VX-809 Pomalidomide

c H 89 2HCl TWS119 Ubenimex (Bestatin)

d Silodosin (Rapaflo) Riluzole (Rilutek) Acetylcysteine

e Ibuprofen (Advil) Ketoprofen (Actron) Ketorolac (Toradol)

f Didanosine (Videx)

g Zalcitabine

h Thioguanine Azacitidine (Vidaza) Bacitracin zinc Simvastatin (Zocor)


1 2 3 4 5

a Proparacaine HCl Pranlukast Carvedilol

b Bifonazole Metoprolol tartrate

Ispinesib (SB-715992)

LY335979 (Zosuquidar 3HCl)

Daclatasvir （BMS-790052） AEE788 (NVP-

AEE788)

Pralatrexate (Folotyn)

Mycophenolate mofetil (CellCept)

Perindopril Erbumine (Aceon)

XL765 (SAR245409)

Saxagliptin (BMS-477118,Onglyza)

Candesartan (Atacand)

PD 0332991 (Palbociclib) Isethionate

Risperidone (Risperdal)

Alendronate (Fosamax)

Amprenavir (Agenerase)

Methyldopa (Aldomet)

Aminoglutethimide (Cytadren)

Aminophylline (Truphylline)

Carbamazepine (Carbatrol)

Torsemide (Demadex)

Adefovir Dipivoxil (Preveon, Hepsera)

Paliperidone (Invega)

Telmisartan (Micardis)

Nevirapine (Viramune)

Toremifene Citrate (Fareston, Acapodene)

Chlorpheniramine Maleate

Betaxolol HCl (Betoptic)

Etidronate (Didronel)

Dapoxetine HCl (Priligy)

Tranexamic acid (Transamin)

c Diclofenac sodium Flutamide (Eulexin) Tropicamide

d Pranoprofen Nicorandil (Ikorel) Meglumine

e Ticlopidine HCl

f PF 573228 BMS-265246 Suplatast tosylate

g Epalrestat Nimesulide Cyproterone acetate

h Captopril (Capoten) Gimeracil


1 2 3 4 5

a Famotidine (Pepcid) Moexipril HCl

b Betaxolol (Betoptic) Detomidine HCl Ambrisentan

c Flunixin meglumin Lapatinib

d Atropine Roflumilast (Daxas) AZD8330 GSK1292263

e LY2940680 KW 2449 PF-4708671 PD 128907 HCl

f SB 743921 AST-1306 SB-505124

g NVP-BHG712 OSI-420 PIK-293 Formestane

h Cyt387 SB590885 Apatinib (YN968D1) TAME CAL-101 (GS-1101)


1 2 3 4 5

a BI6727 (Volasertib) Palomid 529 WP1130 AR-42 (HDAC-42)

b Aloe-emodin Apigenin Artesunate Asiatic acid

Amlodipine (Norvasc)

Fluvastatin sodium (Lescol)

Nefiracetam (Translon)

Tamoxifen Citrate (Nolvadex)

Lacidipine (Lacipil, Motens)

Procarbazine HCl (Matulane)

Ondansetron (Zofran)

Sodium orthovanadate

ENMD-2076 L-(+)-Tartaric acid

Formoterol hemifumarate

Candesartan cilexetil (Atacand)

Phentolamine mesilate

Orphenadrine citrate (Norflex)

Terazosin HCl (Hytrin)

Lovastatin (Mevacor)

Atorvastatin calcium (Lipitor)

Cleviprex (Clevidipine)

Cilazapril monohydrate (Inhibace)

Fosinopril sodium (Monopril)

Almotriptan malate (Axert)

Azasetron HCl (Y-25130)

Mizolastine (Mizollen)

Vinpocetine (Cavinton)

Gabapentin (Neurontin)

Tebipenem pivoxil (L-084)

BGJ398 (NVP-BGJ398)

Avasimibe (CI-1011)

R935788 (Fostamatinib disodium, R788 disodium)

Fesoterodine fumarate (Toviaz)

Arbutin (Uva, p-Arbutin)

c Icariin Luteolin Neohesperidin

d Indirubin Naringenin Sodium Danshensu

e Rotundine Synephrine HCl Tolbutamide Forskolin Equol

f Clozapine (Clozaril)

g Milrinone (Primacor) Mitoxantrone HCl Nateglinide (Starlix)

h


1 2 3 4 5

a Xylazine HCl Maprotiline HCl

b Phenformin HCl Scopine

c Hydralazine HCl Isoprenaline HCl

d Brompheniramine Pioglitazone (Actos)

e Arecoline TAK-733 LDN193189 GSK256066

f PNU-120596 GW3965 HCl URB597

g GSK2126458 MK-0752 WYE-125132

h LY310762 A-674563 AS-252424 PF-00562271


1 2 3 4 5

a CAY10505 CHIR-124 CX-5461 KW-2478 NVP-BSK805 2HCl

b A-769662 RS-127445 CH5132799 KX2-391

Matrine ((+)-Matrine)

Parthenolide ((-)-Parthenolide)

Quercetin (Sophoretin)

Salidroside (Rhodioloside)

Clonidine HCl (Catapres)

Pramipexole (Mirapex)

Domperidone (Motilium)

Donepezil HCl (Aricept)

Manidipine (Manyper)

Manidipine 2HCl (CV-4093)

Pancuronium (Pavulon)

Phenoxybenzamine HCl

Propafenone (Rytmonorm) HCl

Racecadotril (Acetorphan)

Rosiglitazone maleate

Naphazoline HCl (Naphcon)

Epinephrine bitartrate (Adrenalinium)

L-Adrenaline (Epinephrine)

Ritodrine HCl (Yutopar)

Clomipramine HCl (Anafranil)

Tiotropium Bromide hydrate

Rosiglitazone (Avandia)

Amiloride HCl dihydrate

Clomifene citrate (Serophene)

Trazodone HCl (Desyrel)

Tolvaptan (OPC-41061)

Gliclazide (Diamicron)

Noradrenaline bitartrate monohydrate (Levophed)

PF-05212384 (PKI-587)

BMS-806 (BMS 378806)

PF-04929113 (SNX-5422)

5-hydroxymethyl tolterodine (PNU 200577)

GSK1120212 (Trametinib)

GDC-0980 (RG7422)

c TAK-901 AMG 900 ZM 336372 JTC-801

d AZ 3146 PAC-1 PKI-402 GSK1070916

e NVP-BGT226 GW788388 Arry-380

f CH5424802 MK-2048 3-Methyladenine

g PF-5274857 GW842166X M344 RITA (NSC 652287) GW4064

h VU 0357121 WP1066


1 2 3 4 5

a CEP33779 GDC-0068 MPEP INK 128 (MLN0128)

b AM251 NVP-TAE226 RG108 Tideglusib TPCA-1

c SAR131675 BI-D1870 SB-269970 HCl

d StemRegenin 1 Golvatinib (E7050) CTEP

e Alogliptin (SYR-322) TG 100713 T0070907 GW5074

f GW441756 VU 0361737 SB-742457 ZM 323881 HCl

g PF 477736 JNJ-7777120 Ki16198 Pirfenidone Go 6983

h Mozavaptan PF-4981517 Icotinib Salubrinal


1 2 3 4 5

a Paroxetine HCl Zaltoprofen Pazopanib

b Piceatannol Linagliptin (BI-1356) Bindarit

Nilvadipine (ARC029)

TG101348 (SAR302503)

Anacetrapib (MK-0859)

Milciclib (PHA-848125)

Dinaciclib (SCH727965)

Dovitinib Dilactic acid (TKI258 Dilactic acid)

Sotrastaurin (AEB071)

Torcetrapib (CP-529414)

Lonafarnib (SCH66336)

Dabrafenib (GSK2118436)

Semaxanib (SU5416)

Cathepsin Inhibitor 1

Dizocilpine (MK 801)

IEM 1754 dihydrobroMide

Camostat Mesilate (FOY-305)

Tyrphostin 9 (SF 6847)

CHIR-99021 (CT99021) HCl

Plerixafor 8HCl (AMD3100 8HCl)

Aspirin (Acetylsalicylic acid)

Niclosamide (Niclocide)

Vildagliptin (LAF-237)

c Lurasidone HCl Otilonium Bromide Palonosetron HCl

d Ambroxol HCl Amikacin sulfate Naloxone HCl Piracetam (R)-baclofen

e Darifenacin HBr Tripelennamine HCl Entacapone Estradiol valerate Gliquidone

f Betahistine 2HCl Brinzolamide Flumequine Amitriptyline HCl Adrenalone HCl

g Meptazinol HCl Fexofenadine HCl Moclobemide Betulinic acid Pergolide mesylate

h Acebutolol HCl Ampiroxicam Desloratadine


1 2 3 4 5

a Hydroxyzine 2HCl

b Doxapram HCl Methazolamide Valdecoxib

c

d Triamterene Lorcaserin HCl Estradiol Benzoate

e Deoxyarbutin PTC124 (Ataluren)

f PD168393 Brefeldin A VX-661 GSK J4 HCl

g AMG-517 Tenovin-1 GSK2636771 PQ 401

h GW9508 CEP-32496 TAK-438 AZD5363


1 2 3 4 5

a Tariquidar NSC 23766

b GDC-0349 GW2580 Scriptaid Macitentan

Azilsartan (TAK-536)

Solifenacin succinate

Pemirolast (BMY 26517) potassium

Mirabegron (YM178)

Probenecid (Benemid)

Procaine (Novocaine) HCl

Homatropine Methylbromide

Homatropine Bromide

Dibucaine (Cinchocaine) HCl

Tetrahydrozoline HCl

Escitalopram Oxalate

Guanabenz (WY-8678) Acetate

Dequalinium Chloride

Hexamethonium Bromide

Decamethonium Bromide

Sulfacetamide Sodium

Desvenlafaxine Succinate

Tofacitinib citrate (CP-690550 citrate)

Fingolimod (FTY720)

LY2140023 (LY404039)

Oprozomib (ONX 0912)

Rocilinostat (ACY-1215)

Otenabant (CP-945598) HCl

WY 14643 (Pirinixic Acid)

Plerixafor (AMD3100)

PRT062607 (P505-15, PRT2607, BIIB057) HCl

ABT-199 (GDC-0199 )

c Empty Empty Empty Empty Empty

d Empty Empty Empty Empty Empty

e Empty Empty Empty Empty Empty

f Empty Empty Empty Empty Empty

g Empty Empty Empty Empty Empty

h Empty Empty Empty Empty Empty


Product Details:A collection of 1159 inhibitors supplied as lyophilized powder or pre-dissolved DMSO solutions.

2 weeks | 4°C | in DMSO

Blue ice

Yes

6 7 8 9 10 11

FG-4592 Afatinib (BIBW2992)

Erlotinib HCl Gefitinib (Iressa) Imatinib Mesylate

Pazopanib HCl PD0325901 PI-103 Sorafenib (Nexavar) STF-62247

Vorinostat (SAHA) Y-27632 2HCl Elesclomol

GDC-0941 SL327 SB 431542 PHA-665752

MK-2206 2HCl PD153035 HCl SU11274 Belinostat (PXD101)

GSK1904529A PF-04217903 JNJ-26481585 BTZ043 racemate

LY294002 BI 2536

6 7 8 9 10 11

XL147 TW-37

MLN8237 (Alisertib) AT9283 ADL5859 HCl Andarine (GTX-007)

+1-832-582-8158 or [email protected]

96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Saracatinib (AZD0530)

AZD6244 (Selumetinib)

BEZ235 (NVP-BEZ235)

BIBF1120 (Vargatef)

CI-1040 (PD184352)

Dasatinib (BMS-354825)

Deforolimus (Ridaforolimus)

Rapamycin (Sirolimus)

VX-680 (MK-0457, Tozasertib)

Entinostat (MS-275, SNDX-275)

Enzastaurin (LY317615)

Crizotinib (PF-02341066)

AUY922 (NVP-AUY922)

Vismodegib (GDC-0449)

Brivanib (BMS-540215)

LAQ824 (NVP-LAQ824, Dacinostat)

Rucaparib (AG-014699 , PF-01367338)

OSU-03012 (AR-12) Danusertib (PHA-739358)

TAE684 (NVP-TAE684)

Varespladib (LY315920)

PD 0332991 (Palbociclib) HCl

Triciribine (Triciribine phosphate)

XL-184 (Cabozantinib)

Everolimus (RAD001)

Pemetrexed (Alimta)

Brivanib alaninate (BMS-582664)

Cyclopamine Paclitaxel (Taxol) PLX-4720

TRAM-34 AT13387 E7080 (Lenvatinib) ABT-751 Cisplatin

WZ4002 Ostarine (MK-2866) BIIB021 PD98059

BIBR 1532 PIK-90 Anastrozole

Finasteride Irinotecan Cladribine Decitabine Dimesna Dutasteride

Bendamustine HCL Bleomycin sulfate Carboplatin PFI-1

6 7 8 9 10 11

Epirubicin HCl Etoposide (VP-16) Ku-0063794 Idarubicin HCl

Temozolomide Vincristine Agomelatine Vinblastine JNJ-7706621

Celecoxib PD173074 WYE-354

Aniracetam Asenapine Benazepril HCl Biperiden HCl Camptothecin Carmofur

Ftorafur Ifosfamide Megestrol Acetate Mercaptopurine

Ellagic acid Etodolac (Lodine) Etomidate Flumazenil Fluoxetine HCl Flupirtine maleate

Granisetron HCl TG100-115 Ketoconazole Lansoprazole Loratadine

BMS-707035 Amonafide Dorzolamide HCl Gestodene Drospirenone

6 7 8 9 10 11

Mosapride citrate Naftopidil DiHCl

Tenofovir (Viread) Trilostane AS-605240 Clopidogrel (Plavix)

Barasertib (AZD1152-HQPA)

Docetaxel (Taxotere)

Gemcitabine HCl (Gemzar)

Ganetespib (STA-9090)

JNJ 26854165 (Serdemetan)

Regorafenib (BAY 73-4506)

Aprepitant (MK-0869)

Bicalutamide (Casodex)

Fulvestrant (Faslodex)

Abitrexate (Methotrexate)

Nelarabine (Arranon)

Oxaliplatin (Eloxatin)

Evista (Raloxifene HCl)

Amuvatinib (MP-470)

Ramelteon (TAK-375)

AMG-073 HCl (Cinacalcet HCl)

BMS-708163 (Avagacestat)

Floxuridine (Fludara)

Zoledronic Acid (Zoledronate)

Lidocaine (Alphacaine)

Epothilone B (EPO906)

Mizoribine (Bredinin)

Nafamostat mesylate

Omeprazole (Prilosec)

Ondansetron HCl (Zofran)

Tenofovir Disoproxil Fumarate

Alfuzosin HCl (Uroxatral)

Sildenafil citrate Tianeptine sodium Tizanidine HCl Topiramate Varenicline tartrate

PHA-680632 Atazanavir sulfate Thiazovivin

GSK429286A SB 525334 Oligomycin A VX-222

PHA-793887 Naratriptan HCl PIK-93 LY2228820

Irbesartan (Avapro) Tadalafil (Cialis) SB939 (Pracinostat) CCT129202

Hesperadin BIX 02188 BIX 02189 AZD7762 R406 (free base) CP 673451

6 7 8 9 10 11

SB-408124 Dapagliflozin Nebivolol (Bystolic) AZD8055 PHT-427

PD318088 KU-60019 BS-181 HCl Tie2 kinase inhibitor

Apixaban

Naproxen (Aleve)

Cytarabine Zolmitriptan (Zomig) Estrone

Divalproex sodium Lamivudine (Epivir) Eplerenone Piroxicam (Feldene)

Nisoldipine (Sular) Chlorprothixene

Ramipril (Altace) Ranitidine (Zantac) Acadesine Nifedipine (Adalat)

6 7 8 9 10 11

Lomustine (CeeNU)

Felodipine (Plendil) Nizatidine Carbidopa Valsartan (Diovan) Tropisetron

Sumatriptan succinate

Tipifarnib (Zarnestra)

Cilomilast (SB-207499)

Zibotentan (ZD4054)

Safinamide Mesylate (FCE28073)

AS703026 (pimasertib)

Ponatinib (AP24534)

Fludarabine (Fludara)

Ibuprofen Lysine (NeoProfen)

Tosedostat (CHR2797)

Pimobendan (Vetmedin)

Fasudil HCl (HA-1077)

BIRB 796 (Doramapimod)

Semagacestat (LY450139)

Olmesartan medoxomil (Benicar)

Rizatriptan Benzoate (Maxalt)

Pyridostigmine Bromide (Mestinon)

Cefoperazone (Cefobid)

Nitazoxanide (Alinia, Annita)

Orlistat (Alli, Xenical)

Allopurinol (Zyloprim)

Allopurinol Sodium (Aloprim)

Zafirlukast (Accolate)

Enalaprilat dihydrate

Isradipine (Dynacirc)

Flucytosine (Ancobon)

Emtricitabine (Emtriva)

Gemcitabine (Gemzar)

Esomeprazole magnesium (Nexium)

Nimodipine (Nimotop)

Oxybutynin (Ditropan)

Quetiapine fumarate (Seroquel)

Acetylcholine chloride

Amlodipine besylate (Norvasc)

Butoconazole nitrate

Azithromycin (Zithromax)

Flubendazole (Flutelmium)

Cimetidine (Tagamet)

Clemastine Fumarate

Roxatidine acetate HCl

Pregnenolone Sulfamethoxazole Irsogladine Tolfenamic acid

Aripiprazole (Abilify) Amiodarone HCl Adenine Adenine sulfate Adenine HCl

Maraviroc Pyrimethamine PCI-34051

Urapidil HCl Ginkgolide A Uridine Flunarizine 2HCl Rebamipide

Doxifluridine Lornoxicam (Xefo)

Lafutidine Moxonidine Ozagrel HCl Mitiglinide calcium Rosiglitazone HCl Lisinopril (Zestril)

6 7 8 9 10 11

Adiphenine HCl Trimebutine

Bexarotene Temocapril HCl Gabexate mesylate Rasagiline mesylate Naltrexone HCl

Ibutilide fumarate Naftopidil (Flivas) S- (+)-Rolipram Bazedoxifene HCl

Neratinib (HKI-272) CGS 21680 HCl LY2608204 LY2886721

AG14361 LY2784544 MLN2238 MLN9708

AZD8931 GSK461364 R406 SGI-1776 free base BMS 794833

Vinflunine Tartrate AZ 960 DAPT (GSI-IX) PP242

PIK-294 LY2157299

6 7 8 9 10 11

CP-466722 (-)-Huperzine A

Baicalein Baicalin Cryptotanshinone Hesperetin Honokiol

Enalapril maleate (Vasotec)

Metformin HCl (Glucophage)

Methscopolamine (Pamine)

Elvitegravir (GS-9137)

Raltegravir (MK-0518)

Pramipexole 2HCl monohydrate

Ketotifen fumarate (Zaditor)

Memantine HCl (Namenda)

Cyproheptadine HCl (Periactin)

Pioglitazone HCl (Actos)

Strontium ranelate (Protelos)

Duloxetine HCl (Cymbalta)

Ivabradine HCl (Procoralan)

Rivastigmine tartrate (Exelon)

Dexmedetomidine HCl (Precedex)

Levosulpiride (Levogastrol)

Blonanserin (Lonasen)

Cisatracurium besylate (Nimbex)

LDE225 (NVP-LDE225, Erismodegib)

BIBR-1048 (Dabigatran etexilate, Pradaxa)

Rosuvastatin calcium (Crestor)

ITF2357 (Givinostat)

Aliskiren hemifumarate

Mubritinib (TAK 165)

Irinotecan HCl Trihydrate (Campto)

Eltrombopag (SB-497115-GR)

Telatinib (BAY 57-9352)

Ketanserin (Vulketan Gel)

Esomeprazole sodium (Nexium)

Abiraterone Acetate (CB7630)

BKM120 (NVP-BKM120)

CX-4945 (Silmitasertib)

4-Methylumbelliferone (4-MU)

Cytisine (Baphitoxine, Sophorine)

Puerarin (Kakonein) Aloin (Barbaloin)

Astragaloside A

Benserazide

Estriol Hexestrol (Bibenzyl) Imatinib (Gleevec) Loperamide HCl

Nitrendipine Oxymetazoline HCl Ozagrel

Scopolamine HBr Sotalol (Betapace)

6 7 8 9 10 11

DL-Adrenaline Phenytoin (Lepitoin) Alizarin

Scopine HCl Daphnetin

Phenylephrine HCl Phenacetin

Tioxolone Lonidamine Ethisterone

AZD5438 PP-121 OSI-027 R788 (Fostamatinib) LY2603618 (IC-83) Tubastatin A HCl

CCT128930 A66 TAK-875 SNX-2112

WAY-100635 HCl Clinofibrate Ciprofibrate PF-3845 WYE-687

A 922500 BRL-15572 AS-604850

6 7 8 9 10 11

R547 WAY-600 ADX-47273 BMY 7378 TG101209 WAY-362450

GSK1838705A LY2109761 YO-01027 Geldanamycin LY411575 CP-91149

Salinomycin (Procoxacin)

Synephrine (Oxedrine)

5-hydroxytryptophan (5-HTP)

Dioscin (Collettiside III)

Tetrandrine (Fanchinine)

Chrysophanic acid (Chrysophanol)

20-Hydroxyecdysone

10-Hydroxycamptothecin

Apocynin (Acetovanillone)

Amantadine HCl (Symmetrel)

Amfebutamone (Bupropion)

Bupivacaine HCl (Marcain)

Bethanechol chloride

Chlorpromazine (Sonazine)

Fluocinolone acetonide (Flucort-N)

Gallamine triethiodide (Flaxedil)

Neostigmine bromide (Prostigmin)

Olanzapine (Zyprexa)

Olopatadine HCl (Opatanol)

Salbutamol sulfate (Albuterol)

Sulfadoxine (Sulphadoxine)

Tenoxicam (Mobiflex)

Vardenafil Hydrochloride Trihydrate (Vivanza)

Phenytoin sodium (Dilantin)

Dopamine HCl (Inotropin)

Asaraldehyde (Asaronaldehyde)

Trospium chloride (Sanctura)

Tolterodine tartrate (Detrol LA)

Azelastine HCl (Astelin)

Clarithromycin (Biaxin, Klacid)

Medroxyprogesterone acetate

Tetracaine HCl (Pontocaine)

Zidovudine (Retrovir)

Quinapril HCl (Accupril)

Acemetacin (Emflex)

Dehydroepiandrosterone (DHEA)

Mifepristone (Mifeprex)

DCC-2036 (Rebastinib)

NU7441 (KU-57788)

S/GSK1349572 (GSK1349572)

NSC-207895 (XI-006)

Flavopiridol (Alvocidib) HCl

PCI-32765 (Ibrutinib)

PF-03814735 PH-797804 SB 415286

PHA-767491 PF-04691502 CCT137690 CHIR-98014 AZ628 AMG458

AT-406 ARRY334543 Wortmannin Canagliflozin NVP-BVU972

MK-5108 (VX-689) SB705498 MK-2461 Nocodazole CPI-613

AZD2014 TAK-285 A-803467 INCB28060

APO866 (FK866) AZD4547 BAY80-6946 Sirtinol LY364947

6 7 8 9 10 11

AT101 Ciproxifan BYL719 Torin 2

ML133 HCl Torin 1 JNJ 1661010 ARN-509

BRL 54443 BML-190 MRS 2578 SB 271046

VU 0364770 ML130 IMD 0354 VUF 10166 U-104 WHI-P154

Prucalopride (-)-MK 801 Maleate L-NAME HCl IKK-16 A 205804 PF-562271

ZM 306416 GNF-2 CCG 50014 S-Ruxolitinib

WZ 811 Dapivirine GW9662 HC-030031 IOX2

TDZD-8 TAK 715 Pifithrin-α

6 7 8 9 10 11

Niflumic acid Bufexamac Lamotrigine

Pravastatin sodium Rofecoxib (Vioxx)

Dacomitinib (PF299804,PF-00299804)

AG-1478 (Tyrphostin AG-1478)

Crenolanib (CP-868596)

PI3K/HDAC Inhibitor I

Dalcetrapib (JTT-705)

Tofacitinib (CP-690550, Tasocitinib)

Istradefylline (KW-6002)

Galeterone (TOK-001)

Tyrphostin AG 879 (AG 879)

CI994 (Tacedinaline)

Desmethyl Erlotinib (CP-473420)

Epiandrosterone (3β-androsterone)

Baricitinib (LY3009104, INCB28050)

Carfilzomib (PR-171)

Cobicistat (GS-9350)

Lumiracoxib (COX-189)

BAY 11-7082 (BAY 11-7821)

Evacetrapib (LY2484595)

Apoptosis Activator 2

Rivaroxaban (Xarelto)

Ciclopirox ethanolamine

Rimonabant (SR141716)

PMSF (Phenylmethylsulfonyl Fluoride)

Sitaxentan sodium (TBC-11251)

Daunorubicin HCl (Daunomycin HCl)

Bepotastine Besilate

Fosaprepitant dimeglumine

Bosentan Hydrate Azelnidipine Medetomidine HCl

Dexmedetomidine Etravirine (TMC125) Ulipristal Indacaterol Maleate Oxybutynin chloride Milnacipran HCl

Ethynodiol diacetate Abacavir sulfate Altrenogest Anagrelide HCl Atomoxetine HCl

Azatadine dimaleate Ropinirole HCl Triflusal Catharanthine

Ethambutol HCl Doxycycline HCl Pentamidine HCl

Ouabain Allylthiourea Avanafil Tolcapone

6 7 8 9 10 11

Flavoxate HCl Aclidinium Bromide

Nabumetone Sertraline HCl Spironolactone Ropivacaine HCl

Sodium Nitrite Zinc Pyrithione Propranolol HCl Mefenamic Acid Ticagrelor

Desvenlafaxine Histamine 2HCl Timolol Maleate Terbutaline Sulfate

VX-702 PP2 Stattic Embelin IPI-145 (INK1197) AZD2461

(+)-Bicuculline KY02111 (−)-Blebbistatin Zebularine

ZM 39923 HCl SMI-4a BIX01294 VE-821 PRX-08066

GW0742 TCS 359 GSK3787

6 7 8 9 10 11

VU 0364439 Butein Necrostatin-1 UPF 1069 Empty

Empty Empty Empty Empty Empty Empty

Rupatadine Fumarate

Miltefosine (Hexadecylphosphocholine)

Azilsartan Medoxomil (TAK-491)

Benztropine mesylate

Reboxetine mesylate

Trifluoperazine 2HCl

Cabozantinib malate

Sitagliptin phosphate monohydrate

Clinafloxacin (PD127391)

Sodium Monofluorophosphate

Hyoscyamine (Daturine)

Dexamethasone Sodium Phosphate

Bismuth Subsalicylate

Diphemanil Methylsulfate

Vitamin D2 (Ergocalciferol)

Erythromycin Ethylsuccinate

Vitamin D3 (Cholecalciferol)

Sodium 4-Aminosalicylate

Pefloxacin Mesylate Dihydrate

Sodium Phenylbutyrate

NMDA (N-Methyl-D-aspartic acid)

Cilengitide (EMD 121974, NSC 707544)

AG 18 (Tyrphostin 23)

Vortioxetine (Lu AA21004) hydrobromide

Empagliflozin (BI10773)

Tyrphostin AG 1296 (AG 1296)

Apremilast (CC-10004)


Product Details:A collection of 1159 inhibitors supplied as lyophilized powder or pre-dissolved DMSO solutions.

2 weeks | 4°C | in DMSO

Blue ice

Yes

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Item Name SmilesABT-263 (Navitoclax) C1=CC(=CC=C1C2=C(CC(CC2)(C)C)CN3CCN(CC

ABT-737 C1=CC(=CC=C1C(=O)NS(C2=CC=C(C(=C2)[N+]

Linifanib (ABT-869) C12=CC=CC(=C1C(=NN2)N)C3=CC=C(C=C3)NC(

ABT-888 (Veliparib) C1=CC=C2C(=C1C(N)=O)N=C(N2)[C@]3(NCCC3

Axitinib C1(=CC=CC=C1C(=O)NC)SC2=CC3=C(C=C2)C(

Saracatinib (AZD0530) C1=C(C=C2C(=C1OC3CCOCC3)C(=NC=N2)NC4

FG-4592 C12=C(C(=NC(=C1O)C(NCC(O)=O)=O)C)C=C(

AZD6244 (Selumetinib) C1=C2C(=C(C(=C1C(NOCCO)=O)NC3=CC=C(C=C

BEZ235 (NVP-BEZ235) C12=CN=C3C(=C1N(C(N2C)=O)C4=CC=C(C=C4)

BIBF1120 (Vargatef) C1=C(C=C2C(=C1)/C(C(N2)=O)=C(\C3=CC=CC

Afatinib (BIBW2992) C1(=C(C=C(C=C1)NC2=NC=NC3=C2C=C(C(=C3)

Bortezomib (Velcade) C1=CN=CC(=N1)C(N[C@H](C(N[C@H](B(O)O)C

Bosutinib (SKI-606) N1=CC(=C(C2=CC(=C(C=C12)OCCCN3CCN(CC3)

Cediranib (AZD2171) C1(=C(C=C2C(=C1)C(=NC=N2)OC3=C(C4=C(C

Dovitinib (TKI-258) C1=CC=C(C2=C1NC(C(=C2N)C3NC4=C(N=3)C=

CI-1033 (Canertinib) C1(=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C

CI-1040 (PD184352) C1=C(C(=C(C(=C1)C(NOCC2CC2)=O)NC3=CC=C(

Dasatinib (BMS-354825) N1=C(N=C(C=C1NC2=NC=C(S2)C(NC3=C(C=CC

Deforolimus (Ridaforolimus) [C@H]1(C[C@@H](CC[C@@H]1OP(C)(=O)C)C[C@

Erlotinib HCl C1(=CC=CC(=C1)C#C)NC2(=NC=NC3=C2C=C(C

Gefitinib (Iressa) C1(=C(C=C2C(=C1)N=CN=C2NC3=CC=C(C(=C3

Imatinib Mesylate C1(=CC=C(C(=C1)NC2=NC=CC(=N2)C3=CC=CN=

Lapatinib Ditosylate (Tykerb) C1(=C(C=C2C(=C1)N=CN=C2NC3=CC=C(C(=C3)C

Lenalidomide (Revlimid) C1=CC(=C2C(=C1)C(N(C2)C3C(NC(CC3)=O)=O)

Motesanib Diphosphate (AMG-706) C1(=CN=CC=C1CNC2=C(C=CC=N2)C(=O)NC3=CC=

Nilotinib (AMN-107) C1(=CC=C(C(=C1)NC2=NC=CC(=N2)C3=CN=CC=

NVP-AEW541 C1=CC(=CC(=C1)OCC2=CC=CC=C2)C3=CN(C4

Pazopanib HCl C1(=C(C(=CC(=C1)NC2=NC=CC(=N2)N(C3C=CC4

PD0325901 C1=CC(=C(C(=C1C(=O)NOC[C@H](O)CO)NC2=C

PI-103 C12=C(N=C(N=C1N3CCOCC3)C4=CC=CC(=C4)

Rapamycin (Sirolimus) [C@@H]1([C@@H](C[C@@H](CC1)C[C@H]([C@@

Sorafenib (Nexavar) C1(=CC=C(C=C1C(F)(F)F)NC(NC2=CC=C(C=C2)

STF-62247 N1=CC=C(C=C1)C2=CSC(=N2)NC3=CC=CC(=C3

Sunitinib Malate (Sutent) C1(=CC=C2C(=C1)/C(C(N2)=O)=C/C3NC(=C(C=

Tandutinib (MLN518) C1=C(C(=CC2=C1N=CN=C2N3CCN(CC3)C(NC4

Temsirolimus (Torisel) [C@H]1(C[C@@H](CC[C@@H]1OC(C(CO)(CO)C)=

Trichostatin A (TSA) C1=C(C=CC(=C1)C([C@@H](/C=C(/C=C/C(NO)=

Vandetanib (Zactima) C12=C(C(=NC=N1)NC3=C(C=C(C=C3)Br)F)C=C

Vorinostat (SAHA) C1=CC=CC(=C1)NC(=O)CCCCCCC(NO)=O

VX-680 (MK-0457, Tozasertib) C1(=CC(=NC(=N1)SC2=CC=C(C=C2)NC(=O)C3

Y-27632 2HCl [C@@H]1(CC[C@@H](CC1)[C@@H](C)N)C(=O)N

Elesclomol C1=CC=C(C=C1)C(N(NC(CC(NN(C)C(=S)C2=CC

Entinostat (MS-275, SNDX-275) C1=C(C=CC(=C1)C(NC2=CC=CC=C2N)=O)CNC

Enzastaurin (LY317615) C1=CC=C2C(=C1)C(=CN2C3CCN(CC3)CC4=NC=

BMS-599626 (AC480) C1(CN[C@@H](CO1)COC(NC2=CN3C(=C2C)C(=N

Obatoclax mesylate (GX15-070) C1(=CC=C2C(=C1)C=C(N2)C3C=C(/C(N=3)=C/C4

Olaparib (AZD2281) C1=CC=CC2=C1C(=NNC2=O)CC3=CC(=C(C=C3)

Nutlin-3 N1(C(C(N=C1C2=C(C=C(C=C2)OC)OC(C)C)C3=

Masitinib (AB1010) C1(=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3

GDC-0941 C1(=CC=CC2=C1C=NN2)C3=NC(=C4C(=N3)C=C

SL327 C1=CC=CC(=C1C(F)(F)F)/C(=C(/SC2=CC=C(C=C

SB 431542 C1=CC=CC(=N1)C2NC(=NC=2C3=CC4=C(C=C3)

Crizotinib (PF-02341066) C1(=CC(=C(N=C1)N)O[C@@H](C2=C(C=CC(=C2

AUY922 (NVP-AUY922) C1(=CC(=C(C=C1C2=C(C(=NO2)C(=O)NCC)C3=

PHA-665752 C1=CC=C(C(=C1Cl)CS(C2=CC3=C(C=C2)NC(C/3

HA14-1 C1=C(C=C2C(=C1)OC(=C([C@@]2([C@H](C#N)C

ZSTK474 N1=C(N=C(N=C1N2CCOCC2)N3C4=C(N=C3C(F

SB 216763 C1=CC=CC2=C1N(C=C2C3=C(C(NC3=O)=O)C4=

SB 203580 N1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)

SB 202190 C1=C(C=CC(=C1)C2N=C(NC=2C3=CC=NC=C3)C

MK-2206 2HCl C1(=CC=CC=C1)C2(=C(N=C3C(=C2)C4N(C=C3)C

PD153035 HCl C1(=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)

SU11274 C1(=CC=CC(=C1)N(C)S(C2=CC3=C(C=C2)NC(C/

Vismodegib (GDC-0449) C1(=C(C=C(C=C1)NC(C2=CC=C(C=C2Cl)S(C)(=

Brivanib (BMS-540215) C12=C(C(=C(C=C1)OC3=NC=NN4C3=C(C(=C4)O

Belinostat (PXD101) C1(=CC=CC(=C1)/C=C/C(NO)=O)S(NC2=CC=CC

Iniparib (BSI-201) C1=CC(=C(C=C1C(N)=O)[N+](=O)[O-])I

NVP-ADW742 C12=C(N=CN=C1N)N(C=C2C3=CC(=CC=C3)OC

PCI-24781 C1=CC=C2C(=C1)OC(=C2CN(C)C)C(=O)NCCOC

Linsitinib (OSI-906) C1=C(C=C2C(=C1)C=CC(=N2)C3=CC=CC=C3)C4

KU-55933 C1=CC=C2C(=C1)SC3=C(S2)C=CC=C3C4=CC(

GSK1904529A C1=C(C(=C(C=C1)F)NC(C2=C(C=CC(=C2)C3=C

PF-04217903 C12=CC=CN=C1C=CC(=C2)CN3C4=C(N=N3)N=

LAQ824 (NVP-LAQ824, Dacinostat) C1(=CC=C(C=C1)CN(CCO)CCC2=CNC3=C2C=CC

JNJ-26481585 C1=CC=C2C(=C1)C(=CN2C)CNCC3CCN(CC3)C4

BTZ043 racemate C1(=CC(=C2C(=C1)C(N=C(S2)N3CCC4(CC3)OCC(O

Rucaparib (AG-014699 , PF-01367338) C1(C2C=CC(=CC=2)CNC)(=C3C4=C(N1)C=C(C=C

MLN8054 C1=C(C=C2C(=C1)C3=C(CN=C2C4=C(C=CC=C4F

Vatalanib 2HCl (PTK787) C1(=CC=C2C(=C1)C(=NN=C2CC3=CC=NC=C3)NC

U0126-EtOH C1(=CC=C(C(=C1)SC(/N)=C(\C(=C(\SC2=C(C=C

ZM-447439 O1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CN=C3

GDC-0879 C(CN1N=C(C(=C1)C2=CC=C3C(=C2)CCC/3=N/

LY294002 C1=CC(=C2C(=C1)C(C=C(O2)N3CCOCC3)=O)C

OSU-03012 (AR-12) C12=C(C=CC3=C1C=CC(=C3)C4=CC(=NN4C5=CC

Danusertib (PHA-739358) C1(=CC=CC=C1)[C@H](C(N2CC3=C(C2)C(=NN3

TAE684 (NVP-TAE684) C1=CC(=CC(=C1NC2=NC=C(C(=N2)NC3=C(C=CC

BI 2536 C1(=CC=C(C(=C1)OC)NC2=NC=C3C(=N2)N([C

Varespladib (LY315920) C1(N(C2=C(C=1C(C(N)=O)=O)C(=CC=C2)OCC(

Foretinib (GSK1363089, XL880) C1(=CC=C(C=C1)F)NC(C2(C(NC3=CC(=C(C=C

SGX-523 C1=C2C(=CC(=C1)SC3N4C(=NN=3)C=CC(=N4)

GSK690693 C12=C(C(=CN=C1C#CC(C)(O)C)OC[C@@H]3CN

JNJ-38877605 N1=CC=CC2=C1C=CC(=C2)C(C3N4C(=NN=3)C=C

Odanacatib (MK 0822) C1=C(C=CC(=C1)C2=CC=C(C=C2)[C@H](N[C@H](

PD 0332991 (Palbociclib) HCl N1(=C(N=C2C(=C1)C(=C(C(N2C3CCCC3)=O)C(

Triciribine (Triciribine phosphate) [C@H]1([C@@H]([C@H](O[C@@H]1N2C3=C4C(

XL147 C1=CC=C2C(=C1)N=C(C(=N2)NS(=O)(=O)C3=C

XL-184 (Cabozantinib) C12=C(C(=CC=N1)OC3=CC=C(C=C3)NC(C4(C(N

Everolimus (RAD001) C(O)CO[C@H]1[C@@H](C[C@@H](CC1)C[C@@H]

TW-37 C1=CC=CC(=C1C(C)(C)C)S(C2=CC=C(C=C2)NC

Mocetinostat (MGCD0103) C(C1C=CC(=CC=1)CNC2N=C(C=CN=2)C3C=NC=

Abiraterone (CB-7598) C1[C@@H](CC2[C@](C1)([C@]3([C@@](CC=2)([C

SRT1720 N1(=C(C=NC2=CC=CC=C12)C(=O)NC3C(=CC=C

YM155 C1(=CC=C2C(=C1)C(C3=C(C2=O)N(C(=N3CC4=N

INO-1001 C1=CC=C(C=C1C(=O)N)N

MLN8237 (Alisertib) C1=CC=C(C(=C1OC)C2=NCC3=C(C4=C2C=C(C=C

AT9283 N(C(=O)NC1C(=NNC=1)C2NC3C(N=2)=CC(=CC

Pemetrexed (Alimta) C([C@H](NC(C1C=CC(=CC=1)CCC2=CNC3NC(=NC(C

Brivanib alaninate (BMS-582664) C12=C(C(=C(C=C1)OC3=NC=NN4C3=C(C(=C4)O

ADL5859 HCl C1(=CC=C2C(=C1O)C(=CC3(O2)CCNCC3)C4=CC

Andarine (GTX-007) C([C@@](COC1C=CC(=CC=1)NC(=O)C)(C)O)(=O)N

17-AAG (Tanespimycin) C1(=C2C(C(=CC1=O)NC(C(=C\C=C/[C@@H]([C@

17-DMAG HCl (Alvespimycin) C1(=C2C(C(=CC1=O)NC(C(=C\C=C/[C@@H]([C@

AG-490 C1(=C(C=CC(=C1)/C=C(/C(NCC2=CC=CC=C2)=

Ivacaftor (VX-770) C1=C(C(=CC(=C1C(C)(C)C)NC(C2C(C3=C(NC=2

SNS-032 (BMS-387032) C1(=CN=C(O1)CSC2=CN=C(S2)NC(=O)C3CCNCC

Cyclopamine C1[C@@H](CC2[C@](C1)([C@]3([C@@](CC=2)([C

Barasertib (AZD1152-HQPA) C1(=CC=C2C(=C1)N=CN=C2NC3NN=C(C=3)CC

Docetaxel (Taxotere) C1=CC=CC=C1C(=O)O[C@H]2[C@]3(C[C@H](C(=

Gemcitabine HCl (Gemzar) C1(N=C(C=CN1[C@@H]2O[C@H]([C@H](C2(F)F)

Paclitaxel (Taxol) C1=CC=CC(=C1)C(=O)N[C@H]([C@H](C(O[C@H

PLX-4720 C1(=CN=C2C(=C1)C(=CN2)C(=O)C3=C(C(=CC=C

Roscovitine (Seliciclib, CYC202) N1=C2C(=C(N=C1N[C@@H](CO)CC)NCC3=CC=

SNS-314 Mesylate C12(=C(N=CN=C1NCCC3SC(=NC=3)NC(NC4=CC(

NSC 74859 (S3I-201) C1(=CC=C(C=C1)S(OCC(NC2=CC=C(C(=C2)O)C(

Capecitabine (Xeloda) N1=C(C(=CN(C1=O)[C@@H]2O[C@@H]([C@H](

MK-8245 N1N(N=NC=1C2=CC(=NO2)N3CCC(CC3)OC4C(=C

Ganetespib (STA-9090) N1NC(N(C=1C2C(=CC(=C(C=2)C(C)C)O)O)C3=C

TRAM-34 N1(N=CC=C1)C(C2C=CC=CC=2)(C3C=CC=CC=3

AT13387 C(=O)(N1CC2C=CC(=CC(C1)=2)CN3CCN(CC3)C)

E7080 (Lenvatinib) C1(=C(C=C2C(=C1)C(=CC=N2)OC3=CC(=C(C=C

ABT-751 C1=C(C=CC(=C1)S(=O)(=O)NC2=C(N=CC=C2)N

Cisplatin [Pt](N)(Cl)(Cl)N

CP-724714 C1(=CC=C2C(=C1)C(=NC=N2)NC3=CC=C(C(=C3

Valproic acid sodium salt (Sodium valpCCCC(C([O-])=O)CCC.[Na+]

TGX-221 C1=C(C=C(C2N1C(C=C(N=2)N3CCOCC3)=O)C(

WZ3146 C1(=CC=C(C=C1)NC2=NC=C(C(=N2)OC3=CC(=C

CYC116 C1(=NC=CC(=N1)C2SC(=NC=2C)N)NC3=CC=C(

JNJ 26854165 (Serdemetan) C1=C2C(=CC=C1)NC=C2CCNC3=CC=C(C=C3)

WZ4002 C1(=CC(=C(C=C1)NC2=NC=C(C(=N2)OC3=CC(=

Ostarine (MK-2866) C([C@@](COC1C=CC(=CC=1)C#N)(C)O)(=O)NC2

BIIB021 N1=C(N=C2C(=C1Cl)N=CN2CC3=C(C(=C(C=N3)

PD98059 C1=CC=C2C(=C1)C(C=C(O2)C3=CC=CC(=C3N)

Regorafenib (BAY 73-4506) C1=NC(=CC(=C1)OC2=CC(=C(C=C2)NC(NC3=CC=

WZ8040 C1(=CC=C(C=C1)NC2=NC=C(C(=N2)SC3=CC(=C

XAV-939 C1=CC(=CC=C1C(F)(F)F)C2=NC(=C3C(=N2)CC

ENMD-2076 C1(N=C(C=C(N=1)N2CCN(CC2)C)NC3=NNC(=C3

Danoprevir [C@@H]1(CN2[C@@H](C1)C(N[C@@]3(C(NS(=O

Ritonavir C1=CC=CC=C1C[C@@H]([C@H](C[C@H](CC2=C

BIBR 1532 C1=CC=C2C(=C1)C=C(C=C2)/C(=C/C(NC3=C(C

PIK-90 C1=C(C(=C2C(=C1)C3N(C(=N2)NC(C4=CC=CN=

Anastrozole C1=C(C=C(C=C1CN2C=NC=N2)C(C)(C)C#N)C(C

Aprepitant (MK-0869) N1NC(NC=1CN2[C@H]([C@H](OCC2)O[C@@H](C)

Bicalutamide (Casodex) C(C(CS(=O)(=O)C1C=CC(=CC=1)F)(C)O)(=O)NC

Fulvestrant (Faslodex) C1(C=CC2[C@@]3(CC[C@]4([C@H](CC[C@@]([C@

Raltitrexed (Tomudex) C([C@H](CCC(=O)O)NC(=O)C1=CC=C(S1)N(CC2

Thalidomide C1(N(C(C2C=CC=CC1=2)=O)C3C(NC(CC3)=O)=

CUDC-101 C12=C(N=CN=C1NC3=CC(=CC=C3)C#C)C=C(C

TAK-700 (Orteronel) C1=C(C=C2C(=C1)C=C(C=C2)C3(C4N(CC3)C=N

Exemestane C1(C=C[C@@]2([C@@]3(CC[C@]4(C(CC[C@@]([C

Finasteride C1C(N[C@]2([C@](C=1)([C@]3([C@@](CC2)([C@]

Irinotecan N1(CCCCC1)C2CCN(CC2)C(=O)OC3=CC4=C(C5=

Cladribine N1=C(C2=C(N=C1Cl)N(C=N2)[C@H]3C[C@@H](

Decitabine [C@H]1(O[C@@H]([C@H](C1)O)CO)N2C=NC(=

Dimesna S(CCSSCCS([O-])(=O)=O)([O-])(=O)=O.[Na+].[Na

Dutasteride C1C(N[C@]2([C@](C=1)([C@]3([C@@](CC2)([C@]

PIK-75 C1(C(=CN2C(C=1)=NC=C2/C=N/N(S(C3=C(C=CC(=C

Bisoprolol C1(=C(C=CC(=C1)OCC(O)CNC(C)C)COCCOC(C)

Tivozanib (AV-951) C1(=CC=C(C(=C1)Cl)NC(=O)NC2C=C(ON=2)C)

Doxorubicin (Adriamycin) C1(=CC=C2C(=C1OC)C(C3=C(C2=O)C(=C4C(=C3

Adrucil (Fluorouracil) C1(NC(C(=CN1)F)=O)=O

Abitrexate (Methotrexate) N1=C(N=C2C(=C1N)N=C(C=N2)CN(C3=CC=C(C=

Bendamustine HCL C1(=C(C=C2C(=C1)N(C(=N2)CCCC(O)=O)C)N(CC

Nelarabine (Arranon) N1C(=NC2=C(C=1OC)N=CN2[C@H]3[C@H]([C@

Bleomycin sulfate S(=O)(=O)(O)[O-].[C@H](C(C1N=CNC=1)O[C@

Carboplatin [Pt+2].[O-]C(C1(C([O-])=O)CCC1)=O.N.N

PFI-1 C1(=CC=C2C(=C1)CN(C(N2)=O)C)NS(=O)(=O)

Clafen (Cyclophosphamide) C1COP(NC1)(=O)N(CCCl)CCCl

Clofarabine N1=C(N=C2C(=C1N)N=CN2[C@H]3[C@H]([C@@H

YM201636 C1C(=CC=C(N=1)N)C(=O)NC2C=C(C=CC=2)C3

OSI-930 C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(

Dacarbazine (DTIC-Dome) C1=NC(=C(N1)/N=N/N(C)C)C(=O)N

Epirubicin HCl C1(=CC=C2C(=C1OC)C(C3=C(C2=O)C(=C4C(=C3

Oxaliplatin (Eloxatin) [Pt+2].[O-]C(C([O-])=O)=O.C1CC[C@H]([C@@H]

Etoposide (VP-16) [C@@]12([C@@]([C@@H](C3=C([C@@H]1C4=CC(

Ku-0063794 N1=C(N=C2C(=C1N3CCOCC3)C=CC(=N2)C4=CC

Evista (Raloxifene HCl) C1(C=CC2=C(C=1)SC(=C2C(C3=CC=C(C=C3)O

Idarubicin HCl C1(=CC=C2C(=C1)C(C3=C(C2=O)C(=C4C(=C3O)

Fludarabine Phosphate (Fludara) N1C(=NC2=C(C=1N)N=CN2[C@H]3[C@H]([C@@H

Topotecan HCl C1(C=CC2C(C=1CN(C)C)=CC3=C(N=2)C4N(C3)C

2-Methoxyestradiol C1(=C(C=C2C(=C1)[C@]3([C@@](CC2)([C@]4([C

AG-1024 C(C(C#N)=CC1C=C(C(=C(C=1)C(C)(C)C)O)Br)#N

Letrozole C1=CC(=CC=C1C(N2N=CN=C2)C3=CC=C(C=C3

Temozolomide N1(N=NC2N(C1=O)C=NC=2C(N)=O)C

Vincristine C1(=CC2=C(C=C1[C@@]3(C4=C(C5=C(N4)C=CC=

Agomelatine C(C)(=O)NCCC1C=CC=C2C=CC(=CC=12)OC

Amuvatinib (MP-470) C1=CC=C2C(=C1)C3=C(O2)C(=NC=N3)N4CCN(

Vinblastine C123[C@]4(N(CC1)CC=C[C@@]4(CC)[C@@H]([C

JNJ-7706621 C1(=CC=C(C=C1)NC2N=C(N(N=2)C(C3=C(C=CC=

MDV3100 (Enzalutamide) C1(=C(C=CC(=C1)N2C(N(C(C2(C)C)=O)C3=CC=C

Dienogest C1(CCC2=C3CC[C@]4([C@](CC[C@@]([C@](CCC(

Rufinamide (Banzel) C1=CC=C(C(=C1F)CN2N=NC(=C2)C(=O)N)F

Posaconazole C1(=CC=C(C=C1)N2CCN(CC2)C3=CC=C(C=C3)O

Prasugrel (Effient) C(C(C1C(=CC=CC=1)F)N2CCC3=C(C2)C=C(S3)

Ramelteon (TAK-375) C1=C2C(=C3C(=C1)CC[C@H]3CCNC(CC)=O)CC

AMG-073 HCl (Cinacalcet HCl) C1(=C(C=C(C=C1)CCCN[C@@](C2=CC=CC3=C2C=

Celecoxib C1(=CC=C(C=C1)S(N)(=O)=O)N2C(=CC(=N2)C(F

BMS-708163 (Avagacestat) C1(=C(C=C(C=C1)C2N=CON=2)F)CN([C@@H](C(

PD173074 N1=C(N=C2C(=C1)C=C(C(=N2)NC(NC(C)(C)C)

WYE-354 C1=C(C=CC(=C1)C2=NC3=C(C(=N2)N4CCOCC4

Vemurafenib (PLX4032) C1(=CN=C2C(=C1)C(=CN2)C(=O)C3=C(C(=CC=C

IC-87114 C12=C(N=C(N(C1=O)C3=C(C=CC=C3)C)CN4C

BX-795 N1(CCCC1)C(=O)NC2C=C(C=CC=2)NC3N=C(C(

BX-912 N1(CCCC1)C(=O)NC2C=C(C=CC=2)NC3N=C(C(

Amisulpride C1C(N(CC1)CC)CNC(C2=CC(=C(C=C2OC)N)S(C

Aniracetam C1(=CC=C(C=C1)C(N2C(CCC2)=O)=O)OC

Asenapine C12(=C([C@@]3([C@@](C4=C(O1)C=CC(=C4)Cl)(

Benazepril HCl N1(C([C@H](CCC2=C1C=CC=C2)N[C@H](C(OCC

Biperiden HCl C1(=CC(=CC=C1)C(CCN2CCCCC2)(C3CC4C=CC(

Camptothecin O1C([C@@](C2=C(C1)C(N3C(=C2)C4=C(C3)C=

Carmofur C1(C(NC(N(C=1)C(NCCCCCC)=O)=O)=O)F

Celastrol C1(C(=C(C2C(=C1)[C@@]3(C(=CC=2)[C@@]4([C

Cetirizine DiHCl C1(=CC=CC=C1C(C2=CC=C(C=C2)Cl)N3CCN(CC

Cilnidipine C1=CC=C(C=C1C2C(=C(NC(=C2C(OCCOC)=O)C)C

Cilostazol C1C(NC2=C(C1)C=C(C=C2)OCCCCC3N(N=NN=

Epothilone A O1[C@@H]2CCC[C@@H]([C@@H]([C@H](C(C([C

Floxuridine (Fludara) O1[C@@H]([C@H](C[C@H]1N2C=C(C(NC2=O)=

Ftorafur N1C(N(C=C(C1=O)F)[C@@H]2OCCC2)=O

Ifosfamide C1COP(N(C1)CCCl)(NCCCl)=O

Megestrol Acetate C1C(C=C2[C@](C1)([C@]3([C@@](C=C2C)([C@]4

Mercaptopurine N1=CNC2=C(C1=S)NC=N2

Zoledronic Acid (Zoledronate) C1=NC=CN1CC(O)(P(=O)(O)O)P(=O)(O)O

Ki16425 C1=CC=CC(=C1Cl)C(C)OC(=O)NC2C(=NOC=2C

AMG-208 C1(=CC=C2C(=C1)N=CC=C2OCC3N4C(=NN=3)

Costunolide C1C/C(=C/[C@@H]2[C@@H](CC/C(=C/1)C)C(C(

Dexamethasone C1C(C=C2[C@](C=1)([C@]3([C@@](CC2)([C@]4(

Doxazosin mesylate C12(=CC(=C(C=C1C(=NC(=N2)N3CCN(CC3)C(C4

Ellagic acid C12OC(C3C4C1=C(C(OC(C(=C(C=3)O)O)=4)=O)

Etodolac (Lodine) C1=CC2=C(C(=C1)CC)NC3=C2CCO[C@]3(CC(=

Etomidate N1(C(=CN=C1)C(OCC)=O)C(C)C2=CC=CC=C2

Flumazenil C1=C(C=C2C(=C1)N3C(CN(C2=O)C)=C(N=C3)C

Fluoxetine HCl C1(=CC=C(C=C1)OC(CCNC)C2=CC=CC=C2)C(F)(

Flupirtine maleate C1(=CC=C(C=C1)CNC2=NC(=C(C=C2)NC(=O)OC

Fluvoxamine maleate C1(=CC=C(C=C1)/C(CCCCOC)=N/OCCN)C(F)(F)F

Gabapentin HCl C1(CCCC(C1)(CC(O)=O)CN).Cl

Galanthamine HBr C12(=C3C(=CC=C1CN(CC[C@]42[C@@H](O3)C[

Genistein C1(=CC2=C(C(=C1)O)C(C(=CO2)C3=CC=C(C=C

Glimepiride C1=C(C=CC(=C1)S(NC(N[C@@H]2CC[C@H](CC2

Granisetron HCl C1(=C2C(=CC=C1)N(N=C2C(=O)NC3CC4CCCC(C

TG100-115 C1(=C(N=C2C(=N1)C(=NC(=N2)N)N)C3=CC=CC

Ketoconazole C1(=CC=C(C=C1)OC[C@@H]2O[C@@](OC2)(CN

Lansoprazole C1=CC=C2C(=C1)N=C(N2)S(CC3=NC=CC(=C3C)

Lidocaine (Alphacaine) C1=CC=C(C(=C1C)NC(CN(CC)CC)=O)C

Loratadine C1CN(CCC1=C2C3=C(CCC4=C2C=CC(=C4)Cl)C

Losartan potassium C1(=CC(=CC=C1C2=C(C=CC=C2)C3NN=NN=3)CN

GSK1059615 C1(=CC=C2C(=C1)C(=CC=N2)C3=CC=NC=C3)/C

MGCD-265 C1(=CC=CC=C1)CC(NC(NC2=CC=C(C(=C2)F)OC

Rigosertib (ON-01910) C1(=C(C=C(C=C1OC)OC)OC)/C=C/S(CC2=CC=C(C

Ki8751 C1=CN=C2C(=C1OC3=CC=C(C(=C3)F)NC(NC4=

Epothilone B (EPO906) O1[C@@]2(CCC[C@@H]([C@@H]([C@H](C(C([C@

BMS-707035 C1(=CC=C(C=C1)CNC(C2N=C(N(C(C=2O)=O)C)

Amonafide C12C=C(C=C3C1=C(C=CC=2)C(N(C3=O)CCN(C)

Dorzolamide HCl C1([C@@H](S(C2=C([C@@H]1NCC)C=C(S2)S(=O)

Gestodene C1C(C=C2[C@](C1)([C@]3([C@@](CC2)([C@]4([C

Drospirenone C1C(C=C2[C@](C1)([C@]3([C@@]([C@@]4([C@]2(

Ruxolitinib (INCB018424) N1=CN=C2C(=C1C3=CN(N=C3)[C@@H](CC#N)

Isotretinoin C(/C=C(\C=C\C=C(/C=C/C1=C(CCCC1(C)C)C)C)

Lopinavir (ABT-378) C1=CC=C(C(=C1C)OCC(N[C@@H](CC2=CC=CC=

Mianserin HCl C12(N3C(C4=C(CC=1C=CC=C2)C=CC=C4)CN(CC

Minoxidil C1CCN(CC1)C2=CC(=[N+](C(=N2)N)[O-])N

Mizoribine (Bredinin) [C@H]1(O[C@@H]([C@H]([C@@H]1O)O)CO)N2C

Mosapride citrate C1(=C(C=C(C(=C1)C(NCC2OCCN(C2)CC3=CC=C(

Nafamostat mesylate C1(=CC=C(C=C1)NC(=N)N)C(=O)OC2(=CC3=C(C=

Naftopidil DiHCl C1(=C2C(=CC=C1)C=CC=C2)OCC(CN3CCN(CC3

Omeprazole (Prilosec) C1=C(C=C2C(=C1)NC(=N2)S(=O)CC3=C(C(=C(C

Ondansetron HCl (Zofran) C1(=CC=C2C(=C1)C3=C(N2C)CCC(C3=O)CN4C(

Oxcarbazepine N1(C2=C(C(CC3=C1C=CC=C3)=O)C=CC=C2)C(

Pelitinib (EKB-569) C1(=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)

Resveratrol C1(=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)O)O)O

Rocuronium bromide [C@H]1([C@H](C[C@]2([C@](C1)([C@]3([C@@](C

Stavudine O1C(C=CC1CO)N2C(NC(C(=C2)C)=O)=O

Tenofovir Disoproxil Fumarate N1(C=NC2=C(C=1N)N=CN2C[C@H](OCP(OCOC(OC

Tenofovir (Viread) N1=CN=C2C(=C1N)N=CN2C[C@H](OCP(=O)(O)

Trilostane C1(=C([C@@]2([C@]3([C@](C1)([C@]4([C@@](CC

Alfuzosin HCl (Uroxatral) C1(=C(C=C2C(=C1)C(=NC(=N2)N(CCCNC(C3CC

AS-605240 C1(=CC=C2C(=C1)N=CC=N2)/C=C3\SC(NC3=O)

Clopidogrel (Plavix) C1(=CC=CC(=C1Cl)[C@H](N2CCC3=C(C2)C=CS3

Staurosporine [C@]12([C@@H]([C@@H](C[C@@H](O1)N3C4=

Droxinostat C1=C(C=C(C(=C1)OCCCC(NO)=O)C)Cl

Ranolazine 2HCl C1(=C(C(=C(C=C1)C)NC(=O)CN2CCN(CC2)CC(

Repaglinide C1(=C(C=CC(=C1)CC(N[C@H](C2=CC=CC=C2N

Rolipram C1(=C(C=CC(=C1)C2CNC(C2)=O)OC)OC3CCCC

Sildenafil citrate C1(=CC=C(C(=C1)C2=NC3=C(C(N2)=O)N(N=C3C

Sumatriptan succinate C1(=CC=C2C(=C1)C(=CN2)CCN(C)C)CS(NC)(=O

Tianeptine sodium C12(=C(C(C3C(S(N1C)(=O)=O)=CC(=CC=3)Cl)N

Tizanidine HCl C1(C=CC2C(C=1NC3NCCN=3)=NSN=2)Cl.Cl

Topiramate [C@H]12[C@H]([C@H]3[C@](OC1)(COS(N)(=O)=

Varenicline tartrate C([C@@H]([C@H](C(O)=O)O)O)(O)=O.C12C3=

Venlafaxine C1(CCCCC1(C(CN(C)C)C2=CC=C(C=C2)OC)O).C

Voriconazole C1=C(C(=CC(=C1)F)F)[C@@](CN2C=NC=N2)([

Zileuton C1=CC=C2C(=C1)SC(=C2)C(N(O)C(N)=O)C

Aurora A Inhibitor I N1=CC(=C(N=C1NC2=CC=C(C=C2)CC(N3CCN(C

Ispinesib (SB-715992) C1=CC(=CC=C1)CN2C(C3=C(N=C2[C@H](N(CCC

Tipifarnib (Zarnestra) C1=CC(=CC=C1[C@](C2=CN=CN2C)(C3=CC4=C(

PHA-680632 C1(=CC=C(C=C1)C(=O)NC2C3=C(NN=2)CN(C3

Cilomilast (SB-207499) C1(=C(C=CC(=C1)C2(CCC(CC2)(C(=O)O)[H])C

Zibotentan (ZD4054) C1(C(=CC=CN=1)S(=O)(=O)NC2C(=NC(=CN=2)

Atazanavir sulfate O(C(N[C@H](C(N[C@H]([C@H](CN(NC([C@@H](

Thiazovivin C1(SC=C(N=1)C(NCC2=CC=CC=C2)=O)NC3=C

SP600125 C1C=CC2=C(C=1)C(C3=C4C2=NNC4=CC=C3)=

Ofloxacin (Floxin) C1(C(=C2C3=C(C=1)C(C(=CN3C(CO2)C)C(O)=O

Moxifloxacin HCl C1(=C(C(=C2C(=C1)C(C(=CN2C3CC3)C(O)=O)=O

Alfacalcidol C1[C@H](C[C@@H](C(C/1=C\C=C2/[C@]3([C@](

TSU-68 (SU6668) C1=CC=C2C(=C1)/C(C(N2)=O)=C/C3NC(=C(C=3

Safinamide Mesylate (FCE28073) C1(=CC=CC(=C1)COC2=CC=C(C=C2)CN[C@H](C

GSK429286A C1(CC(C(=C(N1)C)C(NC2=C(C=C3C(=C2)C=NN3

AS703026 (pimasertib) C1=C(C=CC(=C1F)NC2=CN=CC=C2C(NC[C@@H]

SB 525334 C1(=CC=C2C(=C1)N=CC=N2)C3NC(=NC=3C4=CC

Oligomycin A C1C[C@@]2(O[C@H]([C@@H]1C)C[C@@H](C)O)[

VX-222 [C@H]1(CC[C@@H](CC1)O)N(C2=C(SC(=C2)C#

LY335979 (Zosuquidar 3HCl) C12(=C(C=CC=C1OC[C@@H](CN3CCN(CC3)[C@@

C1=CC(=CC=C1C2=CN=C(N2)[C@H]3N(CCC3)C(

MC1568 C1=CC(=CC(=C1)C(/C=C/C2=CN(C(=C2)/C=C/C(

HMN-214 C1=CC=CC(=C1N(S(C2=CC=C(C=C2)OC)(=O)=O)

AEE788 (NVP-AEE788) C1=NC(=C2C(=N1)NC(=C2)C3=CC=C(C=C3)CN

PHA-793887 N1N=C(C2=C1C(N(C2)C(C3CCN(CC3)C)=O)(C)C

Naratriptan HCl C1(=CC=C2C(=C1)C(=CN2)C3CCN(CC3)C)CCS(=

PIK-93 C1(=C(C=C(C=C1)C2SC(=NC=2C)NC(C)=O)S(=O

Ponatinib (AP24534) C1C=NN2C(C=1)=NC=C2C#CC3=C(C=CC(=C3)C(

Fludarabine (Fludara) O1[C@@H]([C@H]([C@@H]([C@H]1N2C3=C(N=C

LY2228820 CC(C1=NC(=C(N1)C2=NC3=C(C=C2)N=C(N3CC(C

Pralatrexate (Folotyn) N1=C(N=C2C(=C1N)N=C(C=N2)CC(C3=CC=C(C=

NVP-BEP800 C1=C(C(=CC(=C1Cl)OCCN2CCCC2)C3=NC(=NC4

Mycophenolate mofetil (CellCept) C12=C(C(=C(C(=C1O)C/C=C(/CCC(OCCN3CCO

Dyphylline (Dilor) N1(C(N(C2=C(C1=O)N(C=N2)CC(CO)O)C)=O)C

Perindopril Erbumine (Aceon) CCCC(N[C@H](C(N1[C@@]2([C@](C[C@@H]1C(=O

Irbesartan (Avapro) C1(=CC=C(C=C1)C2=CC=CC=C2C3N=NNN=3)C

Tadalafil (Cialis) N1(CC(N2[C@@](C1=O)(CC3=C([C@H]2C4=CC=

SB939 (Pracinostat) C1(=CC=C2C(=C1)N=C(N2CCN(CC)CC)CCCC)/C

Ibuprofen Lysine (NeoProfen) C1(=CC=C(C=C1)C(C(O)=O)C)CC(C)C.C([C@H]

CCT129202 C1(=CN=C2C(=C1N3CCN(CC3)CC(NC4SC=CN=4)

Tosedostat (CHR2797) [C@@H]([C@@H](C(=O)NO)O)(C(=O)N[C@H](

XL765 (SAR245409) C12=CC=CC=C1N=C(C(=N2)NC3=CC(=CC(=C3)O

AT7519 C1=C(C(=C(C=C1)Cl)C(NC2=CNN=C2C(=O)NC3

MK-1775 C1=CC(=NC(=C1)C(O)(C)C)N2N(C(C3=C2N=C(

Quizartinib (AC220) C1=C(C=CC(=C1)C2N=C3N(C=2)C4C(S3)=CC(=

LY2811376 C1=NC=C(C=N1)C2=C(C=C(C(=C2)[C@]3(N=C(S

Hesperadin C1(=CC=C2C(=C1)/C(C(N2)=O)=C(\C3=CC=CC

BIX 02188 C1=C(C=C2C(=C1)/C(C(N2)=O)=C(/NC3=CC(=

BIX 02189 C1=C(C=C2C(=C1)/C(C(N2)=O)=C(/NC3=CC(=C

Daclatasvir （BMS-790052）

AZD7762 C1(=CC=CC(=C1)C2SC(=C(C=2)NC(N)=O)C(N[

R406 (free base) C1(=C(C=C(C=C1OC)NC2=NC(=C(C=N2)F)NC3=

CP 673451 C1=CC(=C2C(=C1)C=CC(=N2)N3C4=CC=C(C=C

DMXAA (ASA404) C12=C(C(=CC=C1)CC(O)=O)OC3=C(C2=O)C=CC

Telaprevir (VX-950) [C@@]12([C@](CN([C@H]1C(=O)N[C@@H](CCC)

Saxagliptin (BMS-477118,Onglyza) C1C2CC3(CC1CC(C2)(O)C3)[C@@H](C(N4[C@@H]

EX 527 N1C2=C(C3=C1C=CC(=C3)Cl)CCCC2C(=O)N

AM-1241 C1=CC2=C(C=C1)N(C=C2C(C3=CC(=CC=C3I)[N+

SB-408124 C1=C(C=C2C(=C1F)N=C(C=C2NC(NC3=CC=C(C=

Dapagliflozin C1(=CC=C(C(=C1)CC2=CC=C(C=C2)OCC)Cl)[

Nebivolol (Bystolic) C1(=C(C=C2C(=C1)O[C@](CC2)([C@@H](CNC[C@

Pimobendan (Vetmedin) C1=C2C(=CC=C1C3C(CC(NN=3)=O)C)NC(=N2)

AZD8055 C1(=C(C=CC(=C1)C2=NC3=C(C=C2)C(=NC(=N3

PHT-427 C1=C(C=CC(=C1)S(=O)(NC2=NN=CS2)=O)CC

KRN 633 C1(=C(C=C2C(=C1)C(=NC=N2)OC3=CC=C(C(=C

AT7867 C1(=CC=C(C=C1)C2(C3=CC=C(C=C3)C4=CNN=

BMS 777607 C1(=C(N=CC=C1OC2=CC=C(C=C2F)NC(=O)C3C

VX-809 C12=C(C=C(C=C1)C3(C(NC4=NC(=C(C=C4)C)C5

Pomalidomide C1=CC=C2C(=C1N)C(N(C2=O)C3C(NC(CC3)=O)

PD318088 C1=C(C(=C(C(=C1C(NOCC(CO)O)=O)NC2=CC=C(

KU-60019 C1=C(C=CC2=C1CC3=C(S2)C(=CC=C3)C4=CC(

BS-181 HCl C1(=CC(=NC2N1N=CC=2C(C)C)NCCCCCCN)NCC

Fasudil HCl (HA-1077) C1(=C2C(=C(C=C1)S(N3CCNCCC3)(=O)=O)C=CN

BIRB 796 (Doramapimod) C1=C(C2=C(C(=C1)OCCN3CCOCC3)C=CC=C2)N

Tie2 kinase inhibitor C12=C(C=CC(=C1)C3=C(N=C(N3)C4=CC=C(C=C

Candesartan (Atacand) C1(=CC=C(C=C1)C2=CC=CC=C2C3N=NNN=3)C

PD 0332991 (Palbociclib) Isethionate N1(C2C(C(C)=C(C1=O)C(C)=O)=CN=C(N=2)NC

H 89 2HCl C1(=CC=C(C2=C1C=NC=C2)S(NCCNC/C=C/C3=CC

TWS119 C1=CC=C(C=C1O)OC2=NC=NC3=C2C=C(N3)C4

Ubenimex (Bestatin) C1=CC=CC(=C1)C[C@H]([C@@H](C(N[C@H](C(

Apixaban N1=C(C2=C(N1C3=CC=C(C=C3)OC)C(N(CC2)C4

Semagacestat (LY450139) C([C@@H](C(N[C@H](C(N[C@@H]1C2=C(CCN(C

Olmesartan medoxomil (Benicar) N1(CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4

Rizatriptan Benzoate (Maxalt) C1(=CC(=CC2=C1NC=C2CCN(C)C)CN3C=NC=N3

Pyridostigmine Bromide (Mestinon) C1(=C(C=CC=[N+]1C)OC(N(C)C)=O).[Br-]

Cefoperazone (Cefobid) C1(CS[C@]2(N(C=1C(=O)O)C([C@H]2NC(=O)[

Silodosin (Rapaflo) C1=CC=C(C(=C1)OCCN[C@H](C)CC2=CC3=C(C(

Riluzole (Rilutek) C12=C(C=CC(=C1)OC(F)(F)F)N=C(S2)N

Risperidone (Risperdal) C1(=C(C(N2C(=N1)CCCC2)=O)CCN3CCC(CC3)C

Acetylcysteine C(C)(N[C@](C(O)=O)(CS)[H])=O

Alendronate (Fosamax) P(C(CCCN)(P(=O)(O)O)O)(=O)(O)O.[Na].O.O.O

Naproxen (Aleve) C1(=C(C=C2C(=C1)C=C(C=C2)[C@@H](C([O-])=O

Nitazoxanide (Alinia, Annita) C1=CC=CC(=C1OC(C)=O)C(NC2=NC=C(S2)[N+](=

Orlistat (Alli, Xenical) C1([C@H]([C@@H](O1)C[C@H](CCCCCCCCCCC

Allopurinol (Zyloprim) N1=CN=C2C(C1=O)=CNN2

Allopurinol Sodium (Aloprim) C1(=NC2=C(C(N1)=O)C=NN2).[Na+]

Zafirlukast (Accolate) C12=C(C=C(C=C1)NC(OC3CCCC3)=O)C(=CN2C

Ibuprofen (Advil) C1=C(C=CC(=C1)C(C(O)=O)C)CC(C)C

Amprenavir (Agenerase) C1=C(C=CC(=C1)S(N(C[C@H]([C@@H](NC(O[

Methyldopa (Aldomet) C1(=C(C=CC(=C1)C[C@@](C(O)=O)(N)C)O)O

Ketoprofen (Actron) C1=CC=CC(=C1)C(C2=CC=CC(=C2)C(C(O)=O)C

Ketorolac (Toradol) C1(=CC=C(C=C1)C(C2=CC=C3N2CCC3C(=O)O)=

Cytarabine C1(N(C=CC(=N1)N)[C@@H]2O[C@@H]([C@H](

Zolmitriptan (Zomig) C1=C(C=CC2=C1C(=CN2)CCN(C)C)C[C@@H]3N

Enalaprilat dihydrate C1(=CC=CC(=C1)CC[C@@H](C(O)=O)N[C@H](C

Isradipine (Dynacirc) C1C=C(C2C(C=1)=NON=2)C3C(=C(NC(=C3C(OC

Estrone C1=C(C=C2C(=C1)[C@]3([C@@](CC2)([C@]4([C@]

Flucytosine (Ancobon) C1(NC=C(C(=N1)N)F)=O

Aminoglutethimide (Cytadren) C1(=CC=C(C=C1)N)C2(CCC(NC2=O)=O)CC

Aminophylline (Truphylline) NCCN.N1(C(N(C2=C(C1=O)NC=N2)C)=O)C.N3(C

Carbamazepine (Carbatrol) N1(C(=O)N)C2=C(C=CC3=C1C=CC=C3)C=CC=C

Torsemide (Demadex) C1(=C(C=CN=C1)NC2=CC(=CC=C2)C)S(NC(NC(

Didanosine (Videx) [C@H]1(CC[C@@H](O1)N2C3=C(N=C2)C(NC=N

Divalproex sodium C(C([O-])=O)(CCC)CCC.[Na+].C(C(CCC)CCC)(=

Emtricitabine (Emtriva) N1=C(C(=CN(C1=O)[C@H]2O[C@H](SC2)CO)F)

Lamivudine (Epivir) N1=C(C=CN(C1=O)[C@H]2O[C@H](SC2)CO)N

Eplerenone C1C(C=C2[C@](C1)([C@@]34[C@@]([C@@H](C2)

Piroxicam (Feldene) C1=CN=C(C=C1)NC(C2N(S(C3=C(C=2O)C=CC=C

Gemcitabine (Gemzar) N1=C(C=CN(C1=O)[C@@H]2O[C@@H]([C@H](C

Adefovir Dipivoxil (Preveon, Hepsera) C12=C(N=CN=C1N)N(C=N2)CCOCP(OCOC(C(C)(

Zalcitabine [C@H]1(CC[C@@H](O1)N2C(N=C(C=C2)N)=O)

Paliperidone (Invega) C1(=C(C(N2C(=N1)[C@@](CCC2)(O)[H])=O)CC

Telmisartan (Micardis) C1=C(C(=CC=C1)C2=CC=C(C=C2)CN3C(=NC4=

Nevirapine (Viramune) N1(C2CC2)C3=C(NC(C4=C1N=CC=C4)=O)C(=C

Esomeprazole magnesium (Nexium) [Mg+2].C1(=C(C(=C(N=C1)CS(C2=NC3=C([N-]2

Nimodipine (Nimotop) C1(=C(C(C(=C(N1)C)C(OCCOC)=O)C2=CC=CC(=C

Nisoldipine (Sular) C1(=C(C(C(=C(N1)C)C(OC)=O)C2=CC=CC(=C2)[N

Oxybutynin (Ditropan) C1(=CC=CC=C1)C(C2CCCCC2)(C(=O)OCC#CCN

Quetiapine fumarate (Seroquel) OC(/C=C/C(O)=O)=O.C1(=CC=C2C(=C1)N=C(

Chlorprothixene C1=CC=C2C(=C1)SC3=C(C/2=C/CCN(C)C)C=C(C

Thioguanine N1=C(NC2=C(C1=S)NC=N2)N

Toremifene Citrate (Fareston, AcapodeC1(=C(C=CC(=C1)/C(C2=CC=CC=C2)=C(\C3=CC

Azacitidine (Vidaza) [C@H]1([C@H](O[C@H]([C@H]1O)N2C(N=C(N=

Bacitracin zinc C1(C(=O)N[C@H](C(N[C@@H](C(N[C@H](C(N[

Simvastatin (Zocor) C1[C@H](C=C2[C@]([C@@H]1OC(=O)C(CC)(C)C

Ramipril (Altace) C1=CC=CC=C1CC[C@@H](C(=O)OCC)N[C@H](C

Ranitidine (Zantac) N(CC1=CC=C(O1)CSCCN/C(=C/[N+](=O)[O-])NC)

Acadesine [C@@H]1([C@H]([C@@H](O[C@H]1CO)N2C=NC

Acetylcholine chloride CC(OCC[N+](C)(C)C)=O.[Cl-]

Nifedipine (Adalat) C1=CC(=C(C=C1)[N+]([O-])=O)C2C(=C(NC(=C2

Amlodipine besylate (Norvasc) N1(C(=C(C(C(=C1C)C(=O)OC)C2=C(C=CC=C2)C

Chlorpheniramine Maleate C1(=CC=CC(=N1)C(CCN(C)C)C2=CC=C(C=C2)Cl)

Betaxolol HCl (Betoptic) C1(=CC(=CC=C1CCOCC2CC2)OCC(CNC(C)C)O)

Proparacaine HCl C1(=C(C=CC(=C1)C(OCCN(CC)CC)=O)OCCC)N.

Pranlukast C12=C(C=C(C=C1)NC(C3=CC=C(C=C3)OCCCC

Carvedilol C12=CC=CC(=C1C3=C(N2)C=CC=C3)OCC(CN

Butoconazole nitrate C1(=CC=C(C(=C1Cl)SC(CN2C=NC=C2)CCC3=CC=C(

Azithromycin (Zithromax) [C@@H]1([C@@]([C@H](OC([C@H]([C@H]([C@

Flubendazole (Flutelmium) C1(C(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC)

Lomustine (CeeNU) C1CCCC(C1)NC(N(CCCl)N=O)=O

Cimetidine (Tagamet) C1(=C(N=CN1)CSCCN/C(=N/C#N)NC)C

Clemastine Fumarate C1(=C(C=CC(=C1)Cl)[C@](OCC[C@@H]2N(CCC2

Bifonazole C1=CC=CC(=C1)C(C2=CC=C(C=C2)C3=CC=CC

Metoprolol tartrate [C@H](C(O)=O)([C@H](C(O)=O)O)O.C1(=C(C=

Etidronate (Didronel) C(C)(P(=O)(O)O)(P(=O)(O)O)O

Dapoxetine HCl (Priligy) C1(=CC=C2C(=C1OCC[C@@H](C3=CC=CC=C3)N

Tranexamic acid (Transamin) C1C[C@@H](CC[C@@H]1C(O)=O)CN

Roxatidine acetate HCl C(C1=CC(=CC=C1)OCCCNC(COC(C)=O)=O)N2(

Felodipine (Plendil) C1(=C(NC(=C(C1C2=CC=CC(=C2Cl)Cl)C(OC)=O

Nizatidine S1C(=NC(=C1)CSCCN/C(=C\[N+](=O)[O-])NC)CN

Carbidopa C1(=C(C=CC(=C1)C[C@](C(O)=O)(C)NN)O)O

Valsartan (Diovan) C1(=CC=C(C=C1)C2=CC=CC=C2C3N=NNN=3)CN(

Tropisetron C1(=CC=C2C(=C1)C(C=N2)C(OC3C[C@@]4(CC[C@

Diclofenac sodium C1(=C(C(=C(C=C1)Cl)NC2=C(CC([O-])=O)C=CC=C

Amlodipine (Norvasc) N1C(=C(C(C(=C1C)C(=O)OC)C2=C(C=CC=C2)C

Flutamide (Eulexin) C1(=C(C=C(C=C1)NC(C(C)C)=O)C(F)(F)F)[N+](=O

Fluvastatin sodium (Lescol) C12(=C(C=CC=C1)N(C(=C2C3=CC=C(C=C3)F)/C=C

Tropicamide C1=CC=CC(=C1)C(CO)C(=O)N(CC)CC2=CC=NC

Pregnenolone C1[C@@H](CC2[C@](C1)([C@]3([C@@](CC=2)([C

Sulfamethoxazole C1=C(C=CC(=C1)S(NC2C=C(ON=2)C)(=O)=O)N

Irsogladine C1=CC(=C(C=C1Cl)C2=NC(=NC(=N2)N)N)Cl

Enalapril maleate (Vasotec) C1(=CC=CC(=C1)CC[C@H](N[C@H](C(N2[C@@H]

Metformin HCl (Glucophage) NC(NC(N(C)C)=N)=N.Cl

Tolfenamic acid C1(NC2=CC=CC(=C2C)Cl)=C(C=CC=C1)C(O)=O

Pranoprofen C1=CN=C2C(=C1)CC3=C(O2)C=CC(=C3)C(C(O)

Nefiracetam (Translon) C(N1C(CCC1)=O)C(NC2=C(C=CC=C2C)C)=O

Nicorandil (Ikorel) C1=CN=CC(=C1)C(=O)NCCO[N+]([O-])=O

Tamoxifen Citrate (Nolvadex) C1(=CC=C(C=C1)/C(=C(/CC)C2=CC=CC=C2)C3=

Meglumine CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O

Aripiprazole (Abilify) C1=C(C=C2C(=C1)CCC(N2)=O)OCCCCN3CCN(CC

Methscopolamine (Pamine) [Br-].[C@]12([C@@]3([C@]([C@@]([N+]1(C)C)(

Amiodarone HCl C1(=C(C=C(C=C1I)C(=O)C2=C(OC3=C2C=CC=C

Adenine C12=C(N=CN=C1N)NC=N2

Adenine sulfate S(=O)(=O)(O)O.C12(=C(C(=NC=N1)N)NC=N2).C

Adenine HCl C12(=C(C(=NC=N1)N)N=CN2).Cl

Ticlopidine HCl C12(=C(CN(CC1)CC3=C(Cl)C=CC=C3)C=CS2).C

Lacidipine (Lacipil, Motens) C1=CC=CC(=C1C2C(=C(NC(=C2C(OCC)=O)C)C)C

Procarbazine HCl (Matulane) C1(=CC=C(C=C1)CNNC)C(NC(C)C)=O.Cl

Ondansetron (Zofran) C1=CC=C2C(=C1)C3=C(N2C)CCC(C3=O)CN4C(

Sodium orthovanadate [O-][V]([O-])(=O)[O-].[Na+].[Na+].[Na+]

Elvitegravir (GS-9137) C1=CC(=C(C(=C1)Cl)F)CC2=CC3=C(C=C2OC)N

Maraviroc C1=CC=CC(=C1)[C@H](CCN2C3CCC2CC(C3)N4C

Raltegravir (MK-0518) N1(C(=NC(=C(C1=O)O)C(NCC2=CC=C(C=C2)F)=

Pyrimethamine N1=C(N=C(C(=C1N)C2=CC=C(C=C2)Cl)CC)N

Pramipexole 2HCl monohydrate [C@@H]1(CCC2=C(C1)SC(=N2)N)NCCC.O.Cl.Cl

PCI-34051 N1(C=CC2C=CC(=CC1=2)C(=O)NO)CC3C=CC(=

PF 573228 N1C(CCC2C=C(C=CC1=2)NC3N=C(C(=CN=3)C(F

BMS-265246 C(=O)(C1C(=CC(=CC=1F)C)F)C2C(=C3C(=NC=

Suplatast tosylate C1(=CC(=CC=C1NC(CC[S+](C)C)=O)OCC(O)COC

ENMD-2076 L-(+)-Tartaric acid N1(=C(C=C(N1)C)NC2=CC(=NC(=N2)/C=C/C3=C

Formoterol hemifumarate OC(/C=C/C(O)=O)=O.C1(=C(C=CC(=C1)C[C@@

Ketotifen fumarate (Zaditor) C12(C(CC3=C(C(C=1C=CS2)=C4CCN(CC4)C)C=C

Urapidil HCl N1(C(N(C(=CC1=O)NCCCN2CCN(CC2)C3=CC=C

Ginkgolide A O=C1[C@]([C@]2([C@@](O1)(CC34[C@@]52C(O[C

Uridine C1N(C(NC(C=1)=O)=O)[C@@H]2O[C@@H]([C@

Flunarizine 2HCl C1(=CC=C(C=C1)C(N2CCN(CC2)C/C=C/C3=CC=C

Rebamipide C1(C(NC(CC2=CC(NC3=C2C=CC=C3)=O)C(=O)O

Epalrestat C1=CC=CC(=C1)/C=C(/C=C2\SC(N(C2=O)CC(O)

Candesartan cilexetil (Atacand) C1CCCC(C1)OC(OC(OC(=O)C2=CC=CC3=C2N(C

Phentolamine mesilate C1(N(C2=CC=C(C=C2)C)CC3NCCN=3)(=CC(=CC

Nimesulide C1=CC(=CC(=C1NS(=O)(=O)C)OC2=CC=CC=C2)[

Cyproterone acetate [C@H]12C(C=C3[C@]([C@@H]1C2)([C@]4([C@@](

Memantine HCl (Namenda) Cl.C12(CC3CC(C1)(CC(C2)(C3)C)N)C

Cyproheptadine HCl (Periactin) C1(=C2CCN(CC2)C)(C3=C(C=CC4=C1C=CC=C4)

Doxifluridine N1C(C(=CN(C1=O)[C@@H]2O[C@@H]([C@H]([

Pioglitazone HCl (Actos) C1(=CC=C(N=C1)CCOC2=CC=C(C=C2)CC3C(NC(

Lornoxicam (Xefo) N(C1=NC=CC=C1)C(C2N(S(C3=C(C=2O)SC(=C3)

Strontium ranelate (Protelos) C1(N(CC([O-])=O)CC([O-])=O)(=C(C(=C(S1)C([O-]

Captopril (Capoten) C([C@@H]1N(CCC1)C([C@@H](CS)C)=O)(=O)O

Orphenadrine citrate (Norflex) C1(C(OCCN(C)C)C2=CC=CC=C2C)(=CC=CC=C1)

Gimeracil C1(=CNC(C=C1O)=O)Cl

Terazosin HCl (Hytrin) C12(=C(C(=NC(=N1)N3CCN(CC3)C(C4CCCO4)=O

Lovastatin (Mevacor) C1[C@H](C=C2[C@]([C@@H]1OC(=O)[C@H](CC

Lafutidine C1=C(N=CC=C1CN2CCCCC2)OC/C=C\CNC(CS(

Moxonidine N1=C(N=C(C(=C1Cl)NC2=NCCN2)OC)C

Ozagrel HCl C1(=C(C=CC(=C1)/C=C/C(O)=O)CN2C=NC=C2).

Mitiglinide calcium [Ca+2].[C@@H](C([O-])=O)(CC(N1C[C@@]2([C@

Rosiglitazone HCl C1(=CC=NC(=C1)N(CCOC2=CC=C(C=C2)CC3SC(

Lisinopril (Zestril) C1=CC=CC(=C1)CC[C@H](N[C@H](C(N2[C@@H

Atorvastatin calcium (Lipitor) [Ca+2].N1(CC[C@H](C[C@H](CC([O-])=O)O)O

Famotidine (Pepcid) NS(NC(CCSCC1=CSC(=N1)NC(N)=N)=N)(=O)=O

Moexipril HCl C1(=C(C=C2C(=C1)C[C@H](N(C2)C(=O)[C@H](

Cleviprex (Clevidipine) CCCC(OCOC(C1=C(NC(=C(C1C2=CC=CC(=C2Cl)

Cilazapril monohydrate (Inhibace) C1(=CC=C(C=C1)CC[C@H](N[C@H]2CCCN3N(C2

Adiphenine HCl C(C(C1=CC=CC=C1)C2=CC=CC=C2)(OCCN(CC)

Duloxetine HCl (Cymbalta) C1(=CC(=C2C(=C1)C=CC=C2)O[C@@H](CCNC)

Trimebutine C1(=C(C(=CC(=C1)C(OCC(C2=CC=CC=C2)(CC)

Ivabradine HCl (Procoralan) C1(=C2C(=CC(=C1OC)OC)[C@@H](C2)CN(CCCN

Rivastigmine tartrate (Exelon) C1(=CC=CC(=C1)[C@@H](N(C)C)C)OC(N(C)CC)

Dexmedetomidine HCl (Precedex) C1(=C(C(=C(C=C1)C)C)[C@@H](C2NC=NC=2)C)

Betaxolol (Betoptic) C1=CC(=CC=C1CCOCC2CC2)OCC(CNC(C)C)O

Detomidine HCl C1(=CC=CC(=C1C)C)CC2(N=CNC=2).Cl

Fosinopril sodium (Monopril) C(P(O[C@@H](C(C)C)OC(CC)=O)(=O)CC(N1[C@

Almotriptan malate (Axert) C1(=CC=C2C(=C1)C(=CN2)CCN(C)C)CS(N3CCCC

Ambrisentan [C@@H](OC1=NC(=CC(=N1)C)C)(C(O)=O)C(C

Bexarotene C12=C(C=C(C(=C1)C)C(C3=CC=C(C=C3)C(=O)O

Temocapril HCl C1(=CC=CC(=C1)CC[C@H](N[C@@H]2C(N(C[C@

Gabexate mesylate C1(=CC=C(C=C1)C(OCC)=O)OC(=O)CCCCCNC(N

Rasagiline mesylate C1(=CC=C2C(=C1)[C@H](CC2)NCC#C).O=S(=O)

Naltrexone HCl C1(=C(C2=C3C(=C1)C[C@@H]4[C@]5([C@@]3(

Levosulpiride (Levogastrol) C1=CC(=C(C=C1S(=O)(N)=O)C(=O)NC[C@H]2N

Azasetron HCl (Y-25130) C1(=CC(=C2C(=C1)N(C(CO2)=O)C)C(=O)NC3C4C

Mizolastine (Mizollen) C1(NC(C=CN=1)=O)N(C)C2CCN(CC2)C3=NC4C

Flunixin meglumin C1(C(=CC=CN=1)C(=O)O)NC2(C(=C(C=CC=2)C(F

Vinpocetine (Cavinton) C1=CC=C2C(=C1)C3=C4N2C(=C[C@@]5([C@@]4

Lapatinib C1=C(C=C2C(=C1)N=CN=C2NC3=CC=C(C(=C3)

Blonanserin (Lonasen) C1(C2=CC=C(C=C2)F)=C3C(=NC(=C1)N4CCN(

Cisatracurium besylate (Nimbex) C1(=C(C=C2C(=C1)CC[N@@+]([C@@H]2CC3=CC

Ibutilide fumarate CS(=O)(=O)NC1(C=CC(=CC=1)C(CCCN(CCCCCC

Naftopidil (Flivas) C1(=C2C(=CC=C1)C=CC=C2)OCC(CN3CCN(CC

S- (+)-Rolipram C1(=C(C=C(C=C1)[C@H]2CNC(C2)=O)OC3CCC

Bazedoxifene HCl C1(N(C2=CC=C(C=C(C=1C)2)O)CC3=CC=C(OCC

Atropine OS(O)(=O)=O.O.C(C(C1=CC=CC=C1)CO)(O[C@H]

Roflumilast (Daxas) N1=CC(=C(C(=C1)Cl)NC(C2=CC=C(C(=C2)OCC3

Gabapentin (Neurontin) C1CCCC(C1)(CC(O)=O)CN

AZD8330 C1=C(C=CC(=C1F)NC2N(C(C(=CC=2C(NOCCO)=

GSK1292263 C1(C=CC(=CN=1)OCC2CCN(CC2)C3=NC(=NO3)C

Neratinib (HKI-272) C1(=C(C=C2C(=C1)N=CC(=C2NC3=CC=C(C(=C3

LDE225 (NVP-LDE225, Erismodegib) C1(=CC=C(N=C1)N2C[C@@H](O[C@@H](C2)C)C

CGS 21680 HCl C12(=C(N=C(N=C1N)NCCC3=CC=C(C=C3)CCC(

BIBR-1048 (Dabigatran etexilate, PradaC1(=CC=C(C=C1)NCC2N(C3=C(N=2)C=C(C=C3)

LY2608204 C1=C(C=CC(=C1)[C@]2(C[C@@H]2C3CCCCC3)

LY2886721 C1=C(C=CC(=N1)C(NC2=CC=C(C(=C2)[C@@]34N

LY2940680 C1(=NN=C(C2=C1C=CC=C2)N3CCC(CC3)N(C)C(

KW 2449 C1=CC=CC2=C1NN=C2/C=C/C3=CC=C(C=C3)C

Tebipenem pivoxil (L-084) [C@]1(C(N2[C@]1([C@@H](C(=C2C(OCOC(C(C)(

PF-4708671 N1C(=NC2=C1C=CC(=C2)C(F)(F)F)CN3CCN(C

PD 128907 HCl C1(=CC=C2C(=C1)[C@@]3([C@](CO2)(N(CCO3)C

Rosuvastatin calcium (Crestor) [Ca+2].N1(=C(N=C(C(=C1C(C)C)C=C[C@@H](O)

ITF2357 (Givinostat) C1(=CC2=C(C=C1CN(CC)CC)C=CC(=C2)COC(NC

AG14361 C12=C3C=CC=C1N=C(N2CCNC3=O)C4=CC=C(C

LY2784544 C1C(=NN2C(C=1CN3CCOCC3)=NC(=C2CC4=CC=

MLN2238 C1=CC(=CC(=C1Cl)C(NCC(N[C@H](B(O)O)CC(C)

MLN9708 C1=CC(=CC(=C1Cl)C(NCC(N[C@H](B2OC(CC(O2

SB 743921 C1(=CC(=CC=C1)CC2C(C3=C(OC=2[C@H](N(C(=

BGJ398 (NVP-BGJ398) N(C(=O)NC1C(=C(C=C(C=1Cl)OC)OC)Cl)(C)C

AST-1306 C(C=C)(=O)NC1(=CC2=C(N=CN=C(C=C1)2)NC3

SB-505124 C1(=CC=CC(=N1)C2NC(=NC=2C3=CC4=C(C=C3)

Avasimibe (CI-1011) C1=C(C=C(C(=C1C(C)C)CC(NS(OC2=C(C=CC=C2

AZD8931 C1(=C(C=C2C(=C1)C(=NC=N2)NC3=C(F)C(=CC

GSK461364 C1N(CCN(C1)CC2=CC3=C(C=C2)N=CN3C4=CC(=

R406 C1(=C(C=C(C=C1OC)NC2=NC(=C(C=N2)F)NC3=

SGI-1776 free base C1C(=NN2C(C=1)=NC=C2C3=CC=CC(=C3)OC(F)

Aliskiren hemifumarate C(/C=C/C(O)=O)(O)=O.C1(=C(C=C(C=C1)C[C@

BMS 794833 N1=C(C(=C(C=C1)OC2=CC=C(C=C2F)NC(C3=CN

NVP-BHG712 C12=C(N=C(N=C1NC3=CC(=CC=C3C)C(NC4=CC=

OSI-420 C1(=C(C=CC=C1NC2=NC=NC3=C2C=C(C(=C3)O

R935788 (Fostamatinib disodium, R788C1(=C(C(=CC(=C1)NC2=NC=C(C(=N2)NC3=CC=C4C

PIK-293 C1(N(C(C2=C(N=1)C=CC=C2C)=O)C3=C(C=CC

Formestane C1C(C(=C2[C@](C1)([C@]3([C@@](CC2)([C@]4([

Vinflunine Tartrate C1(=C(C=C2C(=C1)[C@]34[C@@](N2C)([C@@](

AZ 960 C1=C(C(=NC(=C1F)NC2C=C(NN=2)C)N[C@H](C

DAPT (GSI-IX) C1(=CC(=CC(=C1)CC(=O)N[C@@H](C)C(N[C@H]

Mubritinib (TAK 165) C1=C(C=CC(=C1)/C=C/C2OC=C(N=2)COC3=CC=

Irinotecan HCl Trihydrate (Campto) C1(CCN(CC1)C2CCN(CC2)C(OC3=CC=C4C(=C3)C

PP242 N1=CN=C2C(=C1N)C(=NN2C(C)C)C3NC4=C(C=3

Cyt387 C1=C(C=CC(=C1)NC2=NC=CC(=N2)C3=CC=C(C

SB590885 N1C(=C(NC=1C2=CC=C(C=C2)OCCN(C)C)C3=C

Apatinib (YN968D1) S(=O)(O)(C)=O.C1=CN=C(C(=C1)C(NC2=CC=C

TAME C1=C(C=CC(=C1)S(N[C@H](C(OC)=O)CCCNC(=N

CAL-101 (GS-1101) C1=CC=C2C(=C1F)C(N(C(=N2)[C@@H](NC3=C

PIK-294 N1=CN=C2C(=C1N)C(=NN2CC3N(C(C4=C(N=3)

Eltrombopag (SB-497115-GR) C1=C(C(=C(C=C1)C2=CC=CC(=C2)C(O)=O)O)N/

LY2157299 C1(=CC=CC(=N1)C2=NN3C(=C(C4=CC=NC5=C4C

Telatinib (BAY 57-9352) N1=C(C2=C(C(=N1)OCC3=CC(=NC=C3)C(=O)NC

Ketanserin (Vulketan Gel) C1=CC=C2C(=C1)C(N(C(N2)=O)CCN3CCC(CC3)

Esomeprazole sodium (Nexium) C1(=CC=C2C(=C1)N=C([N-]2)S(CC3=NC=C(C(=C

BI6727 (Volasertib) [C@H]1(C(N(C2=C(N1C(C)C)N=C(N=C2)NC3=

Palomid 529 C1=C(C=CC(=C1)COC2=C(C=C3C(=C2)OC(C4=

Fesoterodine fumarate (Toviaz) C1(=C(C=CC=C1)[C@@H](CCN(C(C)C)C(C)C)C2

WP1130 C1(=CC=CC(=N1)/C=C(/C(N[C@H](C2=CC=CC=

AR-42 (HDAC-42) C1=CC=C(C=C1)[C@@H](C(NC2=CC=C(C=C2)C

CP-466722 C1=CC=CN=C1C2=NN(C(=N2)N)C3C4C(N=CN=3

Abiraterone Acetate (CB7630) N1=CC(=CC=C1)C2[C@@]3([C@@](CC=2)([C@@]4

BKM120 (NVP-BKM120) C1=C(N=CC(=C1C(F)(F)F)C2=NC(=NC(=C2)N3

CX-4945 (Silmitasertib) C1=NC=C2C(=C1)C(=NC3=C2C=CC(=C3)C(=O)O

(-)-Huperzine A C1(C[C@@]2(C3=C(C[C@](C=1)(C/2=C/C)[H])N

4-Methylumbelliferone (4-MU) C1=C(C=CC2=C1OC(C=C2C)=O)O

Aloe-emodin C12=C(C=C(C=C1O)CO)C(C3=C(C2=O)C(=CC=C

Apigenin C1=C(C2=C(C=C1O)OC(=CC2=O)C3=CC=C(C=C

Arbutin (Uva, p-Arbutin) [C@H]1([C@H]([C@@H]([C@H]([C@@H](O1)OC

Artesunate [C@]12([C@]34[C@@](CC[C@@]1(C)[H])([C@]([

Asiatic acid [C@@H]1([C@@H]([C@]([C@]2([C@](C1)([C@]3(

Baicalein C1(=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3

Baicalin [C@@H]1([C@@H]([C@H]([C@H](O[C@H]1C(=O

Cryptotanshinone C1CC(C2C(C1)=C3C(=CC=2)C4=C(C(C3=O)=O)

Cytisine (Baphitoxine, Sophorine) C12N(C(C=CC=1)=O)C[C@@H]3CNC[C@H]2C3

Hesperetin C1(=CC(=C2C(=C1)O[C@@H](CC2=O)C3=CC=C(

Honokiol C1(=C(C=C(C=C1)C2=CC(=CC=C2O)CC=C)CC=

Icariin [C@H]1([C@H]([C@@H]([C@H](C(O1)OC2C=C(

Luteolin C1(=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C(=C

Matrine ((+)-Matrine) C1CCN2[C@]3([C@]1(CN4[C@@]([C@](CCC2)3[H]

Neohesperidin C1=C(C=C2C(=C1O)C(C[C@H](O2)C3=CC(=CC

Parthenolide ((-)-Parthenolide) C1C[C@@]2([C@H]([C@@H]3[C@@H](CC/C(=C\

Puerarin (Kakonein) C12=C(C(=C(C=C1)O)O[C@H]3[C@@H]([C@H](

Salinomycin (Procoxacin) C1[C@H]([C@@]2(O[C@@]([C@@H]1C)([C@@H](

Synephrine (Oxedrine) C1=C(C=CC(=C1)C(O)CNC)O

5-hydroxytryptophan (5-HTP) C1(=CC=C2C(=C1)C(=CN2)CC(C(O)=O)N)O

Aloin (Barbaloin) [C@@H]1(O[C@]([C@@H]([C@H]([C@H]1O)O)O)

Dioscin (Collettiside III) [C@H]1([C@H]([C@@H](O[C@]([C@H]1O)(O[C@H

Indirubin C1=CC=C2C(=C1)NC(C/2=C3\NC4=C(C3=O)C=

Quercetin (Sophoretin) C1(=CC(=C2C(=C1)OC(=C(C2=O)O)C3=CC=C(C(

Naringenin C1(=CC(=C2C(=C1)O[C@@H](CC2=O)C3=CC=C

Salidroside (Rhodioloside) [C@H]1([C@H]([C@@H]([C@H]([C@@H](O1)O

Sodium Danshensu C1(=C(C=CC(=C1)CC(C(=O)[O-])O)O)O.[Na+]

Tetrandrine (Fanchinine) C1=C2C3=C(C(=C1OC)OC)OC4=C(C=C5C(=C4)

Chrysophanic acid (Chrysophanol) C1=CC(=C2C(=C1)C(C3=C(C2=O)C(=CC(=C3)C)

Astragaloside A [C@@H]1([C@@H]([C@H]([C@@H](OC1)O[C@@H]

20-Hydroxyecdysone [C@H]1([C@@H](C[C@@]2([C@](C1)([C@]3(C(=

10-Hydroxycamptothecin C1=C(C=C2C(=C1)N=C3C(=C2)CN4C3=CC5=C(C

Apocynin (Acetovanillone) C1(C=C(C=CC=1O)C(C)=O)OC

Rotundine C1=C(C(=C2C(=C1)C[C@@]3(N(C2)CCC4=C3C=

Synephrine HCl C1(=C(C=CC(=C1)C(CNC)O)O).Cl

Tolbutamide C1(C=CC(=CC=1)C)S(=O)(=O)NC(=O)NCCCC

Forskolin C1CC([C@]2([C@]([C@@H]1O)([C@]3([C@@]([C

Equol C1[C@@H](CC2C(O1)=CC(=CC=2)O)C3C=CC(=

Amantadine HCl (Symmetrel) C12(CC3CC(C1)CC(C2)(C3)N).Cl

Amfebutamone (Bupropion) C1(=CC=CC(=C1)Cl)C(=O)C(C)NC(C)(C)C.Cl

Benserazide C1(=C(C(=C(C=C1)CNNC(C(N)CO)=O)O)O)O.Cl

Bupivacaine HCl (Marcain) C1(=CC=C(C(=C1C)NC(C2N(CCCC2)CCCC)=O)C)

Bethanechol chloride [N+](CC(OC(N)=O)C)(C)(C)C.[Cl-]

Chlorpromazine (Sonazine) C1(=CC2=C(C=C1)N(C3=C(S2)C=CC(=C3)Cl)CCC

Clonidine HCl (Catapres) C1(=CC=C(C(=C1Cl)NC2NCCN=2)Cl).Cl

Clozapine (Clozaril) N1C2=C(C(=NC3=C1C=CC(=C3)Cl)N4CCN(CC4

Pramipexole (Mirapex) [C@@H]1(CCC2=C(C1)SC(=N2)N)NCCC

Domperidone (Motilium) C(CCN1CCC(CC1)N2C3=C(NC2=O)C=C(C=C3)C

Donepezil HCl (Aricept) C1(=C2C(=CC(=C1OC)OC)C(C(C2)CC3CCN(CC3

Estriol C1=C(C=C2C(=C1)[C@]3([C@@](CC2)([C@]4([C@

Fluocinolone acetonide (Flucort-N) C1C(C=C2[C@](C=1)([C@]3([C@@](C[C@]2([H])F

Gallamine triethiodide (Flaxedil) C1(=CC=CC(=C1OCC[N+](CC)(CC)CC)OCC[N+](CC)(

Hexestrol (Bibenzyl) C1=CC(=CC=C1O)[C@@H]([C@H](CC)C2=CC=C

Imatinib (Gleevec) N1=C(N=C(C=C1)C2=CC=CN=C2)NC3=CC(=CC=

Loperamide HCl C1(=C(C=CC(=C1)C2(CCN(CC2)CCC(C(=O)N(C)

Manidipine (Manyper) C1(=CC(=CC=C1)C2C(=C(NC(=C2C(OCCN3CCN(

Manidipine 2HCl (CV-4093) C1(=CC(=CC=C1)C2C(=C(NC(=C2C(OCCN3CCN(C

Milrinone (Primacor) N1=CC=C(C=C1)C2=C(NC(C(=C2)C#N)=O)C

Mitoxantrone HCl C1(=CC(=C2C(=C1O)C(C3=C(C2=O)C(=CC=C3N

Nateglinide (Starlix) C1[C@H](CC[C@@H](C1)C(N[C@H](CC2=CC=CC

Neostigmine bromide (Prostigmin) C1(=C(C=C(C=C1)[N+](C)(C)C)OC(N(C)C)=O).[Br

Nitrendipine C1=CC(=CC(=C1)[N+]([O-])=O)C2C(=C(NC(=C2

Olanzapine (Zyprexa) N1C2=C(C(=NC3=C1C=CC=C3)N4CCN(CC4)C)C

Olopatadine HCl (Opatanol) C1(=C\CCN(C)C)(/C2=C(OCC3=C1C=CC=C3)C=C

Oxymetazoline HCl C1(=C(C(=C(C(=C1)C)CC2NCCN=2)C)O)C(C)(C)

Ozagrel C1=C(C=CC(=C1)/C=C/C(O)=O)CN2C=NC=C2

Pancuronium (Pavulon) [C@H]1([C@H](C[C@]2([C@](C1)([C@]3([C@@](CC

Phenoxybenzamine HCl C1(=CC=C(C=C1)OCC(N(CCCl)CC2=CC=CC=C2)

Propafenone (Rytmonorm) HCl C1=CC=CC(=C1)CCC(C2=CC=CC=C2OCC(O)C

Racecadotril (Acetorphan) C1=CC=C(C=C1)COC(CNC(C(CSC(=O)C)CC2=C

Rosiglitazone maleate C1(=CC=CC(=N1)N(CCOC2=CC=C(C=C2)CC3C(NC

Salbutamol sulfate (Albuterol) C1(=CC=C(C(=C1)CO)O)C(CNC(C)(C)C)O.S(=O)

Scopolamine HBr O(C([C@@H](C1=CC=CC=C1)CO)=O)[C@H]2(C[C@]3

Sotalol (Betapace) C1(=CC=C(C=C1)NS(C)(=O)=O)C(CNC(C)C)O.Cl

Sulfadoxine (Sulphadoxine) C1=C(C=CC(=C1)S(NC2=NC=NC(=C2OC)OC)(=O

Tenoxicam (Mobiflex) C1=CC=C(N=C1)NC(=O)C2N(S(C3=C(C=2O)SC=

Vardenafil Hydrochloride Trihydrate (VC1(N(CCN(C1)S(C2=CC=C(C(=C2)C3=NN4C(C(N

Xylazine HCl C1(=CC=C(C(=C1C)NC2SCCCN=2)C).Cl

Maprotiline HCl C1(=CC=C2C(=C1)C3(C4=C(C2CC3)C=CC=C4)C

Naphazoline HCl (Naphcon) C12(=CC=CC(=C1C=CC=C2)CC3=NCCN3).Cl

Epinephrine bitartrate (Adrenalinium) C1(=C(C=CC(=C1)[C@@H](O)CNC)O)O.C([C@H]

L-Adrenaline (Epinephrine) C1(=C(C=CC(=C1)[C@@H](O)CNC)O)O

DL-Adrenaline C1(=C(C=CC(=C1)C(CNC)O)O)O

Phenytoin sodium (Dilantin) N1(C(C(N=C1[O-])=O)(C2=CC=CC=C2)C3=CC=CC

Phenytoin (Lepitoin) C1(NC(NC1=O)=O)(C2=CC=CC=C2)C3=CC=CC=

Alizarin C1=CC=C2C(=C1)C(C3=C(C2=O)C=CC(=C3O)O

Dopamine HCl (Inotropin) C1(=C(C=CC(=C1)CCN)O)O.Cl

Asaraldehyde (Asaronaldehyde) C1(=C(C=C(C(=C1)C=O)OC)OC)OC

Ritodrine HCl (Yutopar) C1(=C(C=CC(=C1)[C@]([C@@](NCCC2=CC=C(C=C2

Clomipramine HCl (Anafranil) C(N1C2=C(CCC3=C1C=CC=C3)C=CC(=C2)Cl)CC

Phenformin HCl C1(=CC=C(C=C1)CCNC(NC(=N)N)=N).Cl

Scopine [C@]12([C@@]3([C@]([C@@](N1C)(C[C@@H](C2)O

Tiotropium Bromide hydrate [Br-].O.[C@]12([C@@H]3[C@H]([C@@]([N+]1(C

Scopine HCl Cl.[C@]12([C@@]3([C@]([C@@](N1C)(C[C@@H](C2

Trospium chloride (Sanctura) [Cl-].[C@]12(CC[C@@]([N+]31CCCC3)(C[C@@H

Tolterodine tartrate (Detrol LA) C1(=C(C=C(C(=C1)O)[C@@H](C2=CC=CC=C2)CC

Azelastine HCl (Astelin) C1(=CC=C2C(=C1)C(N(N=C2CC3=CC=C(C=C3)Cl

Daphnetin C1(=CC=C2C(=C1O)OC(C=C2)=O)O

Clarithromycin (Biaxin, Klacid) [C@@]1([C@H](OC([C@@H]([C@@H]([C@@H]([

Rosiglitazone (Avandia) C1=CC=NC(=C1)N(CCOC2=CC=C(C=C2)CC3SC

Amiloride HCl dihydrate C1(=C(N=C(C(=N1)C(NC(N)=N)=O)N)N)Cl.Cl.O.O

Clomifene citrate (Serophene) C1(=CC=CC(=C1)\C(=C(/C2=CC=CC=C2)C3=CC=

Hydralazine HCl C1(=CC2=C(C=C1)/C(NN=C2)=N/N).Cl

Isoprenaline HCl C1(=C(C(=CC(=C1)C(O)CNC(C)C)O)O).Cl

Medroxyprogesterone acetate C1C(C=C2[C@](C1)([C@]3([C@@](C[C@@H]2C)([

Phenylephrine HCl C1(=CC=CC(=C1)[C@](CNC)(O)[H])O.Cl

Tetracaine HCl (Pontocaine) C1(=C(C=CC(=C1)C(OCCN(C)C)=O)NCCCC).Cl

Phenacetin C1=C(C=CC(=C1)NC(C)=O)OCC

Zidovudine (Retrovir) N1C(N(C=C(C1=O)C)[C@@H]2O[C@@H]([C@H](C

Quinapril HCl (Accupril) C1(=CC=CC(=C1)CC[C@H](N[C@H](C(N2[C@@H

Trazodone HCl (Desyrel) C1(=CC=C(C=C1Cl)N2CCN(CC2)CCCN3C(N4C(=

Brompheniramine C1(C(CCN(C)C)C2=CC=CC=N2)(=CC=C(C=C1)Br

Pioglitazone (Actos) C1(=CC=C(N=C1)CCOC2=CC=C(C=C2)CC3C(NC

Tolvaptan (OPC-41061) C(C1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2C)C)(

Gliclazide (Diamicron) C1=C(C=CC(=C1)S(NC(NN2CC3C(C2)CCC3)=O)

Acemetacin (Emflex) CC1N(C2=C(C=1CC(OCC(O)=O)=O)C=C(C=C2)O

Tioxolone C1(=CC=C2C(=C1)OC(S2)=O)O

Dehydroepiandrosterone (DHEA) C1[C@@H](CC2[C@](C1)([C@]3([C@@](CC=2)([C@

Mifepristone (Mifeprex) C1C(C=C2C(C1)=C3[C@@](CC2)([C@]4([C@](C[

Lonidamine C1=CC=C2C(=C1)N(N=C2C(O)=O)CC3=C(C=C(C=

Ethisterone C1C(C=C2[C@](C1)([C@]3([C@@](CC2)([C@]4([C

Arecoline N1(CCC=C(C1)C(OC)=O)C.Br

Noradrenaline bitartrate monohydrate C1(=C(C=CC(=C1)[C@](CN)(O)[H])O)O.OC([C@@]

TAK-733 N1(C=NC2=C(C1=O)C(=C(C(N2C)=O)F)NC3=CC

LDN193189 C1(=CC=C(C=C1)C2C=NC3N(C=2)N=CC=3C4=

GSK256066 C1=CC(=CC(=C1)S(C2=CC(=C3C(=C2)C(=C(C=N

AZD5438 C1=C(C=CC(=C1)NC2=NC=CC(=N2)C3=CN=C(N3

PP-121 C1(=CN=C2C(=C1)C=CN2)C3=NN(C4=C3C(=NC

OSI-027 N1C=NN2C(C=1N)=C(N=C2[C@@H]3CC[C@H](C

R788 (Fostamatinib) C1(=C(C(=CC(=C1)NC2=NC=C(C(=N2)NC3=CC=C

LY2603618 (IC-83) C1=C(C(=CC(=C1OC[C@@H]2CNCCO2)NC(NC3=

Tubastatin A HCl C1(=C(C=CC(=C1)CN2C3=C(C4=C2C=CC=C4)CN

PF-05212384 (PKI-587) N1=C(N=C(N=C1N2CCOCC2)C3=CC=C(C=C3)NC

PNU-120596 C1(=C(C=C(C(=C1)OC)Cl)NC(NC2=NOC(=C2)C)

GW3965 HCl C1(=C(C=C(C=C1)OCCCN(CC2=CC=CC(=C2Cl)C

URB597 C1=C(C=C(C=C1)OC(NC2CCCCC2)=O)C3=CC=C

BMS-806 (BMS 378806) C1=CNC2C(=C1OC)C(=CN=2)C(C(N3[C@@H](C

DCC-2036 (Rebastinib) C1(=C(C=C(C=C1)OC2=CC(=NC=C2)C(NC)=O)F

CCT128930 N1=CN=C2C(=C1N3CCC(CC3)(N)CC4=CC=C(C=

A66 C1SC(=NC=1C2SC(=NC=2C)NC(N3[C@@H](CCC3

TAK-875 C1(=C(C=C(C=C1)COC2=CC=C3C(=C2)OC[C@H]

NU7441 (KU-57788) C1=C(OC2=C(C1=O)C=CC=C2C3=CC=CC4=C3

SNX-2112 C1=CC(=CC(=C1C(N)=O)N[C@@H]2CC[C@H](CC

PF-04929113 (SNX-5422) N1(C2=C(C(=N1)C(F)(F)F)C(CC(C2)(C)C)=O)

GSK2126458 C1(C(=CC(=CC=1)F)F)S(=O)(=O)NC2C(=NC=C

5-hydroxymethyl tolterodine (PNU 200C1=CC=CC=C1[C@H](C2=C(C=CC(=C2)CO)O)CC

MK-0752 C1=CC(=CC=C1Cl)S([C@]2(CC[C@H](CC2)CCC(

WYE-125132 C1(=NC(=NC2=C1C=NN2C3CCC4(CC3)OCCO4)

WAY-100635 HCl C1(N2CCN(CC2)CCN(C3=CC=CC=N3)C(C4CCCCC4

Clinofibrate C1CC(CCC1)(C2=CC=C(C=C2)OC(CC)(C)C(O)=

Ciprofibrate C1=C(C=CC(=C1)OC(C(O)=O)(C)C)C2C(C2)(Cl)C

PF-3845 C1(=CN=C(C=C1)OC2=CC(=CC=C2)CC3CCN(CC3

S/GSK1349572 (GSK1349572) C1(=CC(=C(C=C1)CNC(C2=CN3C(=C(C2=O)O)C(

WYE-687 C1=C(C=CC(=C1)C2=NC3=C(C(=N2)N4CCOCC

LY310762 C1(=CC=C2C(=C1)C(C(N2CCN3CCC(CC3)C(C4=C

A-674563 C1=CC=CC(=C1)C[C@@H](COC2=CC(=CN=C2)

AS-252424 C1(=CC(=C(C=C1)C2OC(=CC=2)/C=C3\SC(NC3=

PF-00562271 C1(=NC(=C(C=C1)CNC2=C(C=NC(=N2)NC3=CC=C

GSK1120212 (Trametinib) C1(N(C(=C2C(=C1C)N(C(N(C2=O)C3CC3)=O)C4

A 922500 C1=CC=C(C=C1)NC(NC2=CC=C(C=C2)C3=CC=

BRL-15572 C1(=CC=C(C=C1)C(C(CN2CCN(CC2)C3=CC(=CC=

NSC-207895 (XI-006) C1CN(CCN1C2C3C(C(=CC=2)[N+](=O)[O-])=NO[N

Flavopiridol (Alvocidib) HCl C1(=C(C(=C2C(=C1O)C(C=C(O2)C3=C(C=CC=C3)

PCI-32765 (Ibrutinib) C1=NC(=C2C(=N1)N(N=C2C3=CC=C(C=C3)OC4

AS-604850 C12=C(C=CC(=C1)/C=C3\SC(NC3=O)=O)OC(O2)

CAY10505 C1(=CC=C(C=C1)C2OC(=CC=2)/C=C3\C(NC(S3)

CHIR-124 C1(C(=C(C2=C(N1)C=CC(=C2)Cl)N[C@H]3C4C

CX-5461 C1=C(N=C2C(=C1)C(C(=C3N2C4=C(S3)C=CC=C

KW-2478 C1=C(C(=C(C(=C1O)C(C2=CC=C(C(=C2)OC)O

NVP-BSK805 2HCl C1(=CC=C2C(=C1C3=CC(=C(C(=C3)F)CN4CCOC

R547 N1=C(N=CC(=C1N)C(C2=C(C(=CC=C2OC)F)F)=

WAY-600 C12=C(C=CC(=C1)C3=NC4=C(C(=N3)N5CCOC

ADX-47273 C1(=CC=C(C=C1)C(N2CCC[C@@H](C2)C3=NC(

BMY 7378 C1(=CC=C(C(=C1)N2CCN(CC2)CCN3C(CC4(CC3

TG101209 C1=C(C=C(C=C1)NC2=NC(=NC=C2C)NC3=CC=C(

WAY-362450 C1=CC=C2C(=C1)C3=C(N2)C(=CN(CC3(C)C)C(C

GDC-0980 (RG7422) C1(=CN=C(N=C1)N)C2=NC(=C3C(=N2)C(=C(S3

A-769662 C1(=CC=C(C=C1)C2=CSC3=C2C(=C(C(N3)=O)

RS-127445 C1=CC(=C2C(=C1C3=CC(=NC(=N3)N)C(C)C)C=

CH5132799 N1=C(N=CC(=C1)C2=C3C(=NC(=N2)N4CCOCC4)

KX2-391 C1=C(C=CC(=C1)C2=CC=C(N=C2)CC(NCC3=C

GSK1838705A N1=C(N=C2C(=C1NC3=CC=CC(=C3C(=O)NC)F)C

LY2109761 C12=C(C=C(C=C1)OCCN3CCOCC3)N=CC=C2C

YO-01027 C1(=CC(=CC(=C1)CC(N[C@H](C(N[C@H]2C3=C

Geldanamycin C1(C(C=C2NC(/C(=C/C=C/[C@@H]([C@H](/C(=

LY411575 C1(=CC(=CC(=C1)[C@@H](C(N[C@H](C(N[C@H

CP-91149 C1(=CC=C2C(=C1)C=C(N2)C(N[C@H]([C@H](C(

TAK-901 C1N(CCC(C1)NC(C2=C(C3=C(C(=C2)C4=CC(=CC

AMG 900 C1=CC(=C(N=C1)OC2=CC=C(C=C2)NC3C4=C(C

ZM 336372 C1(=CC=CC(=C1)C(NC2=CC(=C(C=C2)C)NC(C3

Nilvadipine (ARC029) C1(NC(=C(C(C=1C(=O)OC(C)C)C2=CC=CC(=C2)[

JTC-801 C1(=CC=C(C(=C1)C(=O)NC2=CC3=C(C=C2)N=C

PF-03814735 C12=C(C=C(C=C1)NC3=NC(=C(C=N3)C(F)(F)

PH-797804 C1(=C(C=CC(=C1)C(=O)NC)C)N2C(=CC(=C(C2=

Dacomitinib (PF299804,PF-00299804) C(/C=C/C(NC1=C(C=C2C(=C1)C(=NC=N2)NC3=

AG-1478 (Tyrphostin AG-1478) C1=C2C(=CC(=C1OC)OC)C(=NC=N2)NC3=CC(=

SB 415286 C1(C(=C(C(N1)=O)NC2=CC(=C(C=C2)O)Cl)C3=C(

Crenolanib (CP-868596) C1=CC(=C2C(=C1)C=CC(=N2)N3C=NC4=C3C=C

AZ 3146 C1(=CC(=C(C=C1)NC2=NC3=C(C=N2)N(C(N3C

TG101348 (SAR302503) C1(=CC=C(C=C1)NC2=NC(=C(C=N2)C)NC3=CC=

PAC-1 C1(CN2CCN(CC2)CC(N/N=C/C3=CC=CC(=C3O)

PKI-402 C12=C(N=C(N=C1N3CCOCC3)C4=CC=C(C=C4)N

GSK1070916 C1=CN=C2C(=C1C3=CN(N=C3C4=CC=C(C=C4)N

PHA-767491 C1=NC=CC(=C1)C2NC3=C(C=2)C(NCC3)=O

PF-04691502 N1=C(N=C2C(=C1C)C=C(C(N2[C@H]3CC[C@@H

CCT137690 C1(=CN=C2C(=C1N3CCN(CC3)CC4C=C(ON=4)C

CHIR-98014 C1=C(C=C(C(=C1)C2=NC(=NC=C2N3C=CN=C3)NC

AZ628 C1(=CC=CC(=C1)C(NC2=CC=C(C(=C2)NC3=CC4

AMG458 N1(N(C(C(=C1C)C(=O)NC2C=CC(=CN=2)OC3C

Anacetrapib (MK-0859) C1=C(C=C(C(=C1)C2=CC(=C(C=C2OC)F)C(C)C)C

NVP-BGT226 C(/C=C\C(=O)O)(=O)O.N1=CC2=C(C3=CC(=CC=

GW788388 C(C1C=CC(=CC=1)C2C=C(C=CN=2)C3C(=NNC=

Milciclib (PHA-848125) C12CC(C3=C(C(=NC(=NC=1)NC4=CC=C(C=C4)N

Arry-380 N1C=NC(=C2C=C(C=CC=12)C3OC(=CC=3)CNCC

AT-406 C1=CC(=CC=C1)C(C2=CC=CC=C2)NC(=O)[C@@H

ARRY334543 C12=C(C(=NC=N1)NC3=CC(=C(C=C3)OCC4SC=

Wortmannin C1(C2C3[C@]([C@H](O1)COC)(C4=C(C(C=3OC=

PI3K/HDAC Inhibitor I C1=NC(=NC=C1C(NO)=O)N(C)CC2=CC3=C(S2)

Canagliflozin [C@H]1([C@H]([C@@H]([C@H]([C@@H](O1)C2

NVP-BVU972 C1C(=NN2C(C=1)=NC=C2CC3=CC=C4C(=C3)C=

CH5424802 C1(=CC=C2C(=C1)NC3=C2C(C4=C(C3(C)C)C=C

MK-2048 N1N(C(C2=C(C=1C(=O)NC)N3C(=C2O)C(N(C[C@

3-Methyladenine N1=CN=C2N(C=NC(=C12)N)C

Dinaciclib (SCH727965) C1C[C@H](N(CC1)C2C=C(N3C(N=2)=C(C=N3)CC

Dovitinib Dilactic acid (TKI258 Dilactic N1(C(C(=C(C2C(=CC=CC1=2)F)N)C3=NC4C(N3)

MK-5108 (VX-689) N1=C(C=CC=C1C[C@]2(CC[C@H](CC2)OC3=C(C

Dalcetrapib (JTT-705) C1=CC=CC(=C1NC(C2(CCCCC2)CC(CC)CC)=O)

SB705498 N(C(=O)N[C@H]1CN(CC1)C2C=CC(=CN=2)C(F)(

MK-2461 C12=C(C(C3=C(C=C1)C=CC(=C3)NS(N(C[C@H]

Nocodazole C(NC1=NC2C(N1)=CC(=CC=2)C(=O)C3=CC=CS3

CPI-613 S(CCC(SCC1=CC=CC=C1)CCCCC(O)=O)CC2=

PF-5274857 C1(=CC(=C(N=C1)C2=CC(=NC=C2Cl)N3CCN(CC3

GW842166X C1(N=C(C(=CN=1)C(=O)NCC2CCOCC2)C(F)(F)F

M344 C1(=CC=C(C=C1)C(NCCCCCCC(NO)=O)=O)N(C

RITA (NSC 652287) O1C(=CC=C1C2=CC=C(S2)CO)C3=CC=C(S3)CO

GW4064 C1=CC=C(C=C1C(=O)O)/C=C/C2=C(C=C(C=C2)

AZD2014 C1=C(N=C2C(=C1)C(=NC(=N2)N3[C@H](COCC3

TAK-285 C12=C(C(=NC=N1)NC3=CC=C(C(=C3)Cl)OC4=CC

A-803467 O1C(=CC=C1C2C=CC(=CC=2)Cl)C(=O)NC3C=C

INCB28060 C(C1C(=CC(=CC=1)C2C=NC3N(N=2)C(=CN=3)C

Tofacitinib (CP-690550, Tasocitinib) N1=CN=C2C(=C1N(C)[C@H]3CN(CC[C@@H]3C)

Istradefylline (KW-6002) N1(C(=NC2N(C(N(C(C1=2)=O)CC)=O)CC)/C=C/

Sotrastaurin (AEB071) N1C(C(=C(C1=O)C2N=C(N=C3C=CC=CC=23)N4

Torcetrapib (CP-529414) C12=C(N([C@@H](C[C@H]1N(C(=O)OC)CC3=CC(=

VU 0357121 C1=C(C=CC(=C1)C(NC2=C(C=C(C=C2)F)F)=O)

WP1066 C(/C(=C/C1C=CC=C(N=1)Br)C#N)(=O)N[C@@H

Lonafarnib (SCH66336) C1CC2=C([C@H](C3=C1C=C(C=N3)Br)C4CCN(CC

APO866 (FK866) C(/C=C/C1C=NC=CC=1)(=O)NCCCCC2CCN(CC2

AZD4547 C1(=CC(=CC(=C1)CCC2=CC(=NN2)NC(=O)C3=

BAY80-6946 C(NC1=NC2C(C3N1CCN=3)=CC=C(C=2OC)OCC

Galeterone (TOK-001) [C@]12(C(C3C(CC1)[C@@]4(C(=CC3)C[C@H](

Sirtinol C(C1C(=CC=CC=1)/N=C/C2C(=CC=C3C=CC=CC

LY364947 N1C=CC(=C2C=CC=CC=12)C3C(=NNC=3)C4C=

CEP33779 C1(=CC=CC(=C1)NC2N=C3N(N=2)C=CC=C3C4=

Dabrafenib (GSK2118436) C1(C(=CC=CC=1F)F)S(=O)(=O)NC2C(=C(C=CC=

GDC-0068 C1CN(CCN1C([C@@H](C2=CC=C(C=C2)Cl)CNC(

MPEP C1(C=CC=C(N=1)C#CC2C=CC=CC=2)C

INK 128 (MLN0128) N1=CN=C2C(=C1N)C(=NN2C(C)C)C3=CC4=C(C=

AT101 C1(C(=C(C=C2C(=C(C(=C(C=12)C=O)O)O)C(C)C

Ciproxifan C(=O)(C1C=CC(=CC=1)OCCCC2N=CNC=2)C3(CC3

BYL719 N1([C@@H](CCC1)C(=O)N)C(=O)NC2SC(=C(N=2)

Tyrphostin AG 879 (AG 879) C(/C(=C/C1C=C(C(=C(C=1)C(C)(C)C)O)C(C)(C)C

Torin 2 N1(C(C=CC2C=NC3C(C1=2)=CC(=CC=3)C4C=NC

CI994 (Tacedinaline) C1(=CC=C(C=C1)C(=O)NC2=C(C=CC=C2)N)NC(

AM251 N1(N=C(C(=C1C2C=CC(=CC=2)I)C)C(=O)NN3CC

NVP-TAE226 C1(=CC(=C(C=C1)NC2=NC(=C(C=N2)Cl)NC3=C

RG108 [C@@](N1C(C2=CC=CC=C2C1=O)=O)(CC3C4=C(

Tideglusib S1N(C(N(C1=O)CC2C=CC=CC=2)=O)C3C=CC=

TPCA-1 C1(=C(C=C(S1)C2C=CC(=CC=2)F)C(=O)N)NC(=

ML133 HCl C1(=CC2=C(C=C1)C(=CC=C2)CNCC3=CC=C(C=C

Desmethyl Erlotinib (CP-473420) C1=C(C=CC=C1NC2=NC=NC3=C2C=C(C(=C3)

Torin 1 N1(C(C=CC2C=NC3C(C1=2)=CC(=CC=3)C4C=NC

JNJ 1661010 N1(CCN(CC1)C(=O)NC2=CC=CC=C2)C3=NC(=N

Epiandrosterone (3β-androsterone) C1[C@@H](C[C@]2([C@](C1)([C@]3([C@@](CC2)(

ARN-509 S=C1N(C(C2(N1C3=CC=C(C(=C3)F)C(NC)=O)CC

SAR131675 C12C(N(C(=C(C1=O)C(NC)=O)N)CC)=NC(=CC=2

BI-D1870 C1(=C(C=C(C=C1F)NC2=NC3=C(C=N2)N(C(C(N3

Semaxanib (SU5416) C1=CC=C2C(=C1)/C(C(N2)=O)=C/C3NC(=CC=3C

Cathepsin Inhibitor 1 N1(N=C(C=C1C(=O)N[C@H](C(=O)NCC#N)CC2C=

SB-269970 HCl N1([C@H](CCC1)CCN2CCC(CC2)C)S(=O)(=O)C3

Baricitinib (LY3009104, INCB28050) N1(CC(C1)(CC#N)N2N=CC(=C2)C3C4=C(N=CN=

BRL 54443 N1C=C(C2C=C(C=CC1=2)O)C3CCN(CC3)C

Carfilzomib (PR-171) C1CN(CCO1)CC(N[C@H](C(N[C@H](C(N[C@H](

BML-190 C(CC1=C(N(C2C=CC(=CC1=2)OC)C(C3C=CC(=C

MRS 2578 C(NC1=CC(N=C=S)=CC=C1)(=S)NCCCCNC(NC2

SB 271046 C12C(C(=C(S1)S(=O)(=O)NC3C=C(C(=CC=3)OC

Dizocilpine (MK 801) C12=C([C@]3(C4=C([C@@H](C1)N3)C=CC=C4)

StemRegenin 1 C1(C=CC(=CC=1)CCNC2=NC(=NC3N(C=NC2=3)

Golvatinib (E7050) C1=C(C=CC(=C1F)NC(C2(C(NC3=CC=C(C=C3)

IEM 1754 dihydrobroMide C(CCCCNCC12CC3CC(C1)CC(C2)C3)N.Br.Br

CTEP C1(=CC=NC(=C1)Cl)C#CC2N=C(N(C=2C)C3=CC=

VU 0364770 C1(C=CC=CN=1)C(=O)NC2C=C(C=CC=2)Cl

ML130 C1=CC=C2C(=C1)N(C(=N2)N)S(=O)(C3=CC=C(C

IMD 0354 C1=CC(=CC(=C1O)C(NC2=CC(=CC(=C2)C(F)(F)F)

VUF 10166 C1=CC=C2C(=C1)N=C(C(=N2)Cl)N3CCN(CC3)C

U-104 N(C(NC1=CC=C(C=C1)S(N)(=O)=O)=O)C2=CC=

WHI-P154 N1C=NC(=C2C=C(C(=CC=12)OC)OC)NC3C=C(C(

Alogliptin (SYR-322) C(C1C(=CC=CC=1)CN2C(=CC(N(C2=O)C)=O)N3

TG 100713 C1(C=C(C=CC=1)C2=NC3=C(N=C(N=C(N=C2)3)

T0070907 C(C1C(=CC=C(C=1)[N+](=O)[O-])Cl)(=O)NC2C=

GW5074 C1=C2C(=CC=C1I)NC(C/2=C/C3=CC(=C(C(=C3)B

Camostat Mesilate (FOY-305) C1(C(OC2C=CC(=CC=2)CC(OCC(N(C)C)=O)=O)=

Prucalopride C1(C2=C(CCO2)C(=C(C=1)Cl)N)C(NC3CCN(CC

(-)-MK 801 Maleate [C@@]12(C3=C(C=CC=C3)[C@](CC4=C1C=CC=C4)

L-NAME HCl C([C@H](N)CCCNC(N[N+](=O)[O-])=N)(=O)OC.Cl

IKK-16 C1(C=CC(=CC=1)NC2N=C(C=CN=2)C3=CC4C(S

A 205804 C12=C(C(=CN=C1)SC3=CC=C(C=C3)C)C=C(S2)

PF-562271 C1=NC(=C(C=C1)CNC2=C(C=NC(=N2)NC3=CC=C4

GW441756 C1=CC=C2C(=N1)C(C(N2)=O)=CC3=CN(C4=C3

VU 0361737 C1(C=CC=CN=1)C(=O)NC2C=C(C(=CC=2)Cl)OC

SB-742457 C1C=CC=CC=1S(C2C=NC3C(=CC=CC=3C=2)N4

Tyrphostin 9 (SF 6847) C1(C(=C(C=C(C=1)C=C(C#N)C#N)C(C)(C)C)O)C(

ZM 323881 HCl C1(C(=CC(=C(C=1)NC2N=CN=C3C=C(C=CC=23)

ZM 306416 C12C(C=C(C(=C1)OC)OC)=NC=NC=2NC3=C(C=C

GNF-2 C1=CC(=CC(=C1)C(=O)N)C2=NC=NC(=C2)NC3=

Cobicistat (GS-9350) C1(CN(C(N[C@H](C(N[C@H](CC[C@@H](NC(O

CCG 50014 C1(=CC=C(C=C1)CN2C(N(SC2=O)C3=CC=C(C=C

S-Ruxolitinib N1C2=C(C(=NC=1)C3=CN(N=C3)[C@H](C4CCC

Lumiracoxib (COX-189) C1=CC=C(C(=C1Cl)NC2=CC=C(C=C2CC(O)=O)C

PF 477736 C1=C(C=C2C3=C1C(NN=CC(=C(N2)C4C=NN(C=

JNJ-7777120 C1(=CC=C2C(=C1)C=C(N2)C(N3CCN(CC3)C)=O)

Ki16198 C1=CC(=CC=C1C2=C(C(=NO2)C)NC(OC(C3=C(

Pirfenidone N1(C2C=CC=CC=2)C(C=CC(=C1)C)=O

Go 6983 C1(=CC=C2C(=C1)C(=CN2CCCN(C)C)C3C(NC(

WZ 811 C1(C=CC(=CC=1)CNC2C=CC=CN=2)CNC3C=C

BAY 11-7082 (BAY 11-7821) C1(S(/C=C/C#N)(=O)=O)C=CC(=CC=1)C

Dapivirine N1=C(N=CC=C1NC2C(=CC(=CC=2C)C)C)NC3=C

GW9662 C1(=CC(=CC=C1Cl)[N+](=O)[O-])C(NC2C=CC=C

HC-030031 C12N(C=NC(N(C(N(C1=O)C)=O)C)=2)CC(NC3C=

IOX2 C(CNC(=O)C1C(N(C2C=CC=CC(C=1O)=2)CC3C

Mozavaptan C12=C(C(CCCN1C(C3=CC=C(C=C3)NC(C4=C(C

PF-4981517 C1(C2C3C(=NC=NC=3N4C[C@@H](N5CCCCC5)C

Icotinib C1=C(C=CC=C1NC2=NC=NC3=C2C=C4C(=C3)

Salubrinal C12C(NC(NC(NC(/C=C/C3=CC=CC=C3)=O)C(Cl)

CHIR-99021 (CT99021) HCl C1(=NC=C(C(=N1)C2=CC=C(C=C2Cl)Cl)C3NC=C

Evacetrapib (LY2484595) C1(=CC(=CC(=C1)CN([C@]2(CCCN(C3=C2C=C(C=C

TDZD-8 S1N(C(N(C1=O)CC2C=CC=CC=2)=O)C

Apoptosis Activator 2 C12=C(C=CC=C1)N(C(C2=O)=O)CC3=CC(=C(C=C

TAK 715 C(C1C=CC=CC=1)(=O)NC2C=C(C=CN=2)C3=C(

Pifithrin-α C1(CCC2=C(C1)N(C(S2)=N)CC(C3=CC=C(C=C3)

Rivaroxaban (Xarelto) C1=C(C=CC(=C1)N2C(COCC2)=O)N3C(OC(C3)C

Paroxetine HCl [C@@H]1([C@@H](CNCC1)COC2=CC3=C(C=C2)

Zaltoprofen C1=CC=C2C(=C1)C(CC3=C(S2)C=CC(=C3)C(C)

Pazopanib C1(C(=CC=C(C=1)NC2N=C(C=CN=2)N(C)C3C=CC

Plerixafor 8HCl (AMD3100 8HCl) C1(C=CC(=CC=1)CN2CCNCCCNCCNCCC2)CN3(CCN

Aspirin (Acetylsalicylic acid) C1=CC=CC(=C1C(=O)O)OC(C)=O

Niflumic acid C1(C(=CC=CN=1)C(=O)O)NC2C=C(C=CC=2)C(F)

Ciclopirox ethanolamine C1(=C(C=C(N(C1=O)O)C2CCCCC2)C).NCCO

Rimonabant (SR141716) N1(N=C(C(=C1C2C=CC(=CC=2)Cl)C)C(=O)NN3C

Bufexamac C1(C=CC(=CC=1)OCCCC)CC(=O)NO

Lamotrigine N1=NC(=NC(=C1C2C(=C(C=CC=2)Cl)Cl)N)N

PMSF (Phenylmethylsulfonyl Fluoride)C1(C=CC=CC=1)CS(=O)(=O)F

Piceatannol C1(C(=CC(=CC=1)/C=C/C2C=C(C=C(C=2)O)O)O

Niclosamide (Niclocide) C(C1C(=CC=C(C=1)Cl)O)(=O)NC2C(=CC(=CC=2)[N

Linagliptin (BI-1356) C1=CC=C2C(=C1)N=C(N=C2C)CN3C(N(C4=C(C

Bindarit C(C(C)(OCC1=NN(C2C=CC=CC1=2)CC3C=CC=C

Vildagliptin (LAF-237) C1N([C@@H](CC1)C#N)C(CNC23CC4CC(C2)CC(

Sitaxentan sodium (TBC-11251) C1(=C(C=CS1)S(=O)(=O)[N-]C2=C(C(=NO2)C)C

Daunorubicin HCl (Daunomycin HCl) C1(=CC=C2C(=C1OC)C(C3=C(C2=O)C(=C4C(=C3

Pravastatin sodium C1([C@@H](C=C2[C@]([C@@H]1OC([C@@H](C)CC

Bepotastine Besilate N1(CCC(CC1)O[C@H](C2C=CC=CN=2)C3C=CC(=

Fosaprepitant dimeglumine C1(=CC=C(C=C1)F)[C@H]2([C@H](OCCN2CC3=

Rofecoxib (Vioxx) C1=C(C=CC(=C1)C2=C(C(OC2)=O)C3=CC=CC=C

Lurasidone HCl N1(CCN(CC1)C2=NSC3=C2C=CC=C3)C[C@H]4([C@

Azilsartan (TAK-536) C1(=NC2C(N1CC3C=CC(=CC=3)C4C(=CC=CC=4

Otilonium Bromide C(COC(C1C=CC(=CC=1)NC(C2C(=CC=CC=2)OCCC

Solifenacin succinate [C@H]1(N(CCC2C=CC=CC1=2)C(=O)O[C@]3(CN

Palonosetron HCl C1(N(C[C@@]2(C3C(=CC=CC1=3)CCC2)[H])[C@

Bosentan Hydrate C1(C=CC(=CC=1)C(C)(C)C)S(=O)(=O)NC2(=N

Rupatadine Fumarate C12(C(=CC=CN=1)CCC3C(C2=C4CCN(CC4)CC5C=

Azelnidipine C1(=C(C(C(=C(N1)C)C(=O)OC(C)C)C2C=C(C=C

Miltefosine (Hexadecylphosphocholine[N+](CCOP(=O)([O-])OCCCCCCCCCCCCCCCC)(

Azilsartan Medoxomil (TAK-491) C1(=NC2C(N1CC3C=CC(=CC=3)C4C(=CC=CC=4

Medetomidine HCl C1(=C(C(C)=CC=C1)C)C(C2N=CNC=2)C.Cl

Ambroxol HCl [C@@H]1(CC[C@@H](CC1)NCC2C(=C(C=C(C=2)B

Amikacin sulfate [C@@H]1([C@@H](C[C@@H]([C@@H]([C@@H]1O

Naloxone HCl C12([C@]34[C@@]5([C@@H](CC=1C=CC(=C2O[C

Piracetam N1(C(CCC1)=O)CC(=O)N

(R)-baclofen C1=C(C=CC(=C1)[C@@H](CC(O)=O)CN)Cl

Dexmedetomidine C1=C(C(=C(C=C1)C)C)[C@@H](C2NC=NC=2)C

Etravirine (TMC125) C1(N=C(N=C(C=1Br)N)NC2C=CC(C#N)=CC=2)O

Ulipristal [C@H]1(C2[C@]([C@]3([C@](C1)([C@@](CC3)(

Indacaterol Maleate N1(C(C=CC2C(=CC=C(C1=2)O)[C@H](CNC3CC4C

Oxybutynin chloride C1(=CC=CC=C1C(C2CCCCC2)(C(OCC#CCN(CC)

Milnacipran HCl [C@H]1([C@@](C1)(C(N(CC)CC)=O)C2=CC=CC=

Darifenacin HBr C1(=CC=C2C(=C1)CCO2)CCN3(CC[C@H](C3)C(

Tripelennamine HCl C(CN(C1C=CC=CN=1)CC2C=CC=CC=2)N(C)C.C

Entacapone C(/C(=C/C1C=C(C(=C(C=1)[N+](=O)[O-])O)O)C#

Estradiol valerate C1=C(C=C2C(=C1)[C@]3([C@@](CC2)([C@]4([C@

Gliquidone C1(C=CC(=CC=1)CCN2C(C3C=C(C=CC(C(C2=O)

Ethynodiol diacetate C1[C@@H](C=C2[C@](C1)([C@]3([C@@](CC2)([C@

Benztropine mesylate C1(C[C@@H]2C[C@@H](C[C@@H]1N2C)OC(C3

Abacavir sulfate S(=O)(=O)(O)O.[C@H]1(C=C[C@@H](C1)N2C=

Altrenogest C1C(C=C2C(C1)=C3[C@@](CC2)([C@]4([C@](C=C

Anagrelide HCl C1(=C(C(=C2C(=C1)NC3N(C2)CC(N=3)=O)Cl)Cl).

Atomoxetine HCl C(C[C@H](C1C=CC=CC=1)OC2C(=CC=CC=2)C)

Betahistine 2HCl C1(C=CC=CN=1)CCNC.Cl.Cl

Brinzolamide S1(N(C[C@@H](C2=C1SC(=C2)S(=O)(=O)N)NC

Flumequine C12C(C(=CN3C(CCC(=C31)C=C(C=2)F)C)C(=O)

Amitriptyline HCl C(CC=C1C2C(CCC3C1=CC=CC=3)=CC=CC=2)N(

Adrenalone HCl O=C(CNC)C1(C=CC(O)=C(O)C=1).Cl

Azatadine dimaleate C12(C(=CC=CN=1)CCC3C(C2=C4CCN(CC4)C)=C

Ropinirole HCl N1(C(CC2C(=CC=CC1=2)CCN(CCC)CCC)=O).Cl

Reboxetine mesylate C1(=CC(=C(C=C1)O[C@H](C2=CC=CC=C2)[C@@

Triflusal C(C1C(=CC(=CC=1)C(F)(F)F)OC(=O)C)(=O)O

Trifluoperazine 2HCl C1(C(=CC=C2SC3C=CC=CC=3N(C2=1)CCCN4CCN(

Catharanthine C1=CC=C2C(=C1)C3=C(N2)[C@@]4([C@@]5([N@]

Meptazinol HCl C1(C=C(C=CC=1)C2(CN(CCCC2)C)CC)O.Cl

Fexofenadine HCl C1(CCN(CC1)CCCC(C2=CC=C(C=C2)C(C(O)=O)

Moclobemide C(C1C=CC(=CC=1)Cl)(=O)NCCN2CCOCC2

Betulinic acid [C@@]12([H])[C@@](C(O)=O)(CC[C@@]3([C@@]

Pergolide mesylate C12(C3[C@@]4([C@@](CC1=CNC=2C=CC=3)(N(C

Cabozantinib malate C12(=C(C(=CC=N1)OC3=CC=C(C=C3)NC(C4(C(N

Sitagliptin phosphate monohydrate C1(=C(C(=CC(=C1F)C[C@H](CC(N2CC3N(CC2)C(=

Ethambutol HCl [C@H](NCCN[C@@H](CC)CO)(CC)CO.Cl.Cl

Doxycycline HCl Cl.C1=CC(=C2C(=C1)[C@H]([C@@]3(C(C2=O)=C

Clinafloxacin (PD127391) C12N(C3CC3)C=C(C(C=1C=C(C(=C2Cl)N4CC(N)

Pentamidine HCl C1(C=CC(=CC=1)OCCCCCOC2C=CC(=CC=2)C(N)

Pemirolast (BMY 26517) potassium C1(C2[N-]N=NN=2)(C(N3C(=NC=1)C(=CC=C3)C)=

Mirabegron (YM178) S1C(=NC(=C1)CC(=O)NC2C=CC(=CC=2)CCNC

Acebutolol HCl C1(=C(C=C(C=C1)NC(CCC)=O)C(C)=O)OCC(CNC

Ampiroxicam C1(C2=C(S(N(C=1C(NC3C=CC=CN=3)=O)C)(=O

Desloratadine C1CC(CCN1)=C2C3=C(CCC4=C2N=CC=C4)C=C(

Sodium Monofluorophosphate P(=O)(F)([O-])[O-].[Na+].[Na+]

Hyoscyamine (Daturine) C1(CC2N(C(C1)CC2)C)OC([C@@H](C3C=CC=C

Ouabain [C@]12([C@]3([H])[C@]([H])([C@@]4([C@](C

Allylthiourea N(C(N)=S)CC=C

Avanafil C(NCC1N=CC=CN=1)(=O)C2=C(NCC3=CC(=C(C=

Tolcapone C1(C(C2=CC=C(C=C2)C)=O)C=C(C(=C(C=1)O)O)[

Probenecid (Benemid) C1=C(C=CC(=C1)C(=O)O)S(N(CCC)CCC)(=O)=O

Procaine (Novocaine) HCl C1(C(OCCN(CC)CC)=O)(C=CC(=CC=1)N).Cl

Homatropine Methylbromide [Br-].[C@]12(CC[C@@]([N+]1(C)C)(C[C@@H](C

Homatropine Bromide [C@@H]1(C[C@@]2(N([C@@](C1)(CC2)[H])C)[H

Hydroxyzine 2HCl C(N1CCN(CC1)CCOCCO)(C2=CC=C(C=C2)Cl)C3(

Flavoxate HCl C12(=C(C(C(=C(O1)C3=CC=CC=C3)C)=O)C=CC

Dexamethasone Sodium Phosphate C1(C(C=C2[C@](C=1)([C@]3([C@@](CC2)([C@]4([

Aclidinium Bromide C(C(O[C@H]1C[N+]2(CCCOC3C=CC=CC=3)CCC1(

Bismuth Subsalicylate C1(=CC=C(C(=C1)C([O-])=O)[O-]).[Bi+3].[OH-]

Diphemanil Methylsulfate C(=C1CC[N+](CC1)(C)C)(C2=CC=CC=C2)C3(C=C

Vitamin D2 (Ergocalciferol) [C@]12([C@](/C(=C/C=C3\C(CC[C@H](C3)O)=C

Doxapram HCl C1(C(C(CCN2CCOCC2)CN1CC)(C3=CC=CC=C3)

Dibucaine (Cinchocaine) HCl C12(=C(C=C(N=C1C=CC=C2)OCCCC)C(NCCN(CC

Methazolamide C1(/SC(S(N)(=O)=O)=NN1C)=N/C(C)=O

Tetrahydrozoline HCl N1(=C(NCC1)C2C3=CC=CC=C(CCC2)3).Cl

Valdecoxib C1=CC=CC(=C1)C2=NOC(=C2C3=CC=C(C=C3)S(

Nabumetone C1(=CC=C2C(=C1)C=CC(=C2)CCC(C)=O)OC

Sertraline HCl C12(=C([C@@H](CC[C@H]1NC)C3=CC=C(C(=C3)

Spironolactone C1C(C=C2[C@](C1)([C@]3([C@@]([C@@H](C2)SC

Ropivacaine HCl C1(CC[C@H](N(C1)CCC)C(=O)NC2=C(C=CC=C2C

Erythromycin Ethylsuccinate C1(O[C@H]([C@]([C@@H]([C@H](C([C@@H](C[

Vitamin D3 (Cholecalciferol) C1[C@H](CCC(C/1=C/C=C2/[C@]3([C@](CCC2)

Escitalopram Oxalate C12(=CC=C(C=C1COC2(CCCN(C)C)C3=CC=C(C=

Guanabenz (WY-8678) Acetate C1(=CC=C(C(=C1Cl)/C=N/NC(N)=N)Cl).CC(O)=O

Dequalinium Chloride C1(=CC=CC2=C1C(=CC(=[N+]2CCCCCCCCCC[N+]3

Hexamethonium Bromide C[N+](CCCCCC[N+](C)(C)C)(C)C.[Br-].[Br-]

Decamethonium Bromide [N+](CCCCCCCCCC[N+](C)(C)C)(C)(C)C.[Br-].[Br-

Sodium 4-Aminosalicylate [O-]C(C1=C(C=C(C=C1)N)O)=O.[Na+]

Sodium Nitrite [O-]N=O.[Na+]

Zinc Pyrithione C1=CC=C2[N+](=C1)[O-][Zn+2]3([S-]2)[O-][N+]4

Propranolol HCl C1(=CC=C2C(=C1)C(=CC=C2)OCC(CNC(C)C)O).

Mefenamic Acid C(C1C(=CC=CC=1)NC2C(=C(C=CC=2)C)C)(=O)

Ticagrelor N1(C2=C(C(N[C@H]3[C@@H](C4=CC(F)=C(C=C

Triamterene C1(=NC2=C(C(=N1)N)N=C(C(=N2)N)C3=CC=CC

Sulfacetamide Sodium C1(=C(C=CC(=C1)S([N-]C(C)=O)(=O)=O)N).[Na+]

Lorcaserin HCl C1(NC[C@@H](C2=C(C1)C=CC(=C2)Cl)C).Cl

Estradiol Benzoate C1=C(C=C2C(=C1)[C@]3([C@@](CC2)([C@]4([C

Desvenlafaxine Succinate C1(C(CCCC1)(C(CN(C)C)C2=CC=C(C=C2)O)O).

Desvenlafaxine C1C(CCCC1)(C(CN(C)C)C2=CC=C(C=C2)O)O

Histamine 2HCl C1(CCN)(=CNC=N1).Cl.Cl

Pefloxacin Mesylate Dihydrate C12(=C(C(C(=CN1CC)C(O)=O)=O)C=C(C(=C2)N3

Timolol Maleate C1(C(OC[C@H](CNC(C)(C)C)O)=NSN=1)N2(CCOC

Sodium Phenylbutyrate C(CCCC1C=CC=CC=1)(=O)O[Na]

Terbutaline Sulfate C1(C(CNC(C)(C)C)O)(C=C(C=C(C=1)O)O).C2(C(

Deoxyarbutin C1=C(C=CC(=C1)OC2CCCCO2)O

Tofacitinib citrate (CP-690550 citrate) N1(=CN=C2C(=C1N(C)[C@H]3CN(CC[C@@H]3C)

Fingolimod (FTY720) C1(=CC=C(C=C1)CCCCCCCC)CCC(CO)(N)CO.C

LY2140023 (LY404039) [C@@]12([C@@]([C@](CS1(=O)=O)(N)C(=O)O)([H

PTC124 (Ataluren) C1=C(C=CC=C1C(=O)O)C2=NOC(=N2)C3=CC=

VX-702 C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(N)=O)

PP2 N1=CN=C2C(=C1N)C(=NN2C(C)(C)C)C3=CC=C(

Stattic C1(=CC=C2C(=C1)S(C=C2)(=O)=O)[N+](=O)[O-]

Embelin C1(C(C(=CC(C=1O)=O)O)=O)CCCCCCCCCCC

IPI-145 (INK1197) C1=CC=C2C(=C1Cl)C(N(C(=C2)[C@H](C)NC3

AZD2461 C1=CC=C2C(=C1)C(NN=C2CC3=CC=C(C(=C3)C

PD168393 C1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)B

Brefeldin A C1C[C@@H](OC(/C=C/[C@H]([C@]2([C@](/C=C/C

Oprozomib (ONX 0912) N([C@H](C(N[C@H](C(N[C@H](C(C1(OC1)C)=

VX-661 C12=CC=C(C=C1OC(O2)(F)F)C3(C(=O)NC4=C(C

GSK J4 HCl C1(C2=C(CCN(C1)C3=NC(=NC(=C3)NCCC(OCC)

(+)-Bicuculline [C@]1(C2C(=C3C(=CC=2)OCO3)C(O1)=O)([C@@

NMDA (N-Methyl-D-aspartic acid) [C@@H](CC(O)=O)(C(O)=O)NC

Cilengitide (EMD 121974, NSC 707544)N1(C([C@H](NC([C@@H](NC(=O)CNC([C@@H]

KY02111 C1(C=C(C(=CC=1)OC)OC)CCC(=O)NC2SC3C(N=

(−)-Blebbistatin C1(C=CC=CC=1)N2C3[C@](C(C4C(=CC=C(C=4)C

Zebularine [C@@H]1(O[C@H]([C@H]([C@H]1O)O)N2C(N=

AMG-517 C1(=CC=C(C=C1)C2=NC=NC(=C2)OC3=CC=CC4=

Tenovin-1 C1=C(C=CC(=C1)C(NC(NC2=CC=C(C=C2)NC(C)=

Rocilinostat (ACY-1215) C1=CC=CC(=C1)N(C2=CC=CC=C2)C3=NC=C(C

GSK2636771 C1=C(C=C2C(=C1C(=O)O)N=C(N2CC3=CC=CC(=

PQ 401 N(C(=O)NC1C=C(N=C2C=CC=CC=12)C)C3=C(C=

ZM 39923 HCl C(CCN(C(C)C)CC1C=CC=CC=1)(=O)C2(C=C3C=

SMI-4a S1C(NC(C/1=C\C2C=C(C=CC=2)C(F)(F)F)=O)=O

BIX01294 N1(C(=NC(=C2C=C(C(=CC=12)OC)OC)NC3CCN(

VE-821 C1(C(=NC=C(N=1)C2C=CC(=CC=2)S(=O)(=O)C

AG 18 (Tyrphostin 23) C1(C=C(C#N)C#N)=CC(=C(C=C1)O)O

PRX-08066 C(/C=C\C(=O)O)(=O)O.C(C1C(=CC=C(C=1)CN2

Otenabant (CP-945598) HCl N1(CCC(CC1)(C(=O)N)NCC)C2(=NC=NC3N(C(=N

GW9508 C(=O)(CCC1=CC=C(NCC2C=C(OC3=CC=CC=C3

CEP-32496 N(C(=O)NC1=NOC(=C1)C(C(F)(F)F)(C)C)C2C

TAK-438 N(CC1=CN(C(=C1)C2C(=CC=CC=2)F)S(=O)(=O)

AZD5363 N1(CCC(CC1)(C(=O)N[C@@H](CCO)C2C=CC(=C

GW0742 N1=C(SC(=C1C)CSC2C=C(C)C(=CC=2)OCC(=O)O

Vortioxetine (Lu AA21004) hydrobromiC1(=CC=C(C(=C1)C)SC2=CC=CC=C2N3CCNCC3

Empagliflozin (BI10773) [C@H]1([C@H]([C@@H]([C@H]([C@@H](O1)C2

TCS 359 C12=C(C(=C(S1)NC(C3C=C(C(=CC=3)OC)OC)=

Tyrphostin AG 1296 (AG 1296) N1C(=CN=C2C=C(C(=CC=12)OC)OC)C3C=CC=

GSK3787 C1=NC(=CC=C1C(F)(F)F)S(=O)(CCNC(C2=CC=C

Tariquidar C1=CC=C2C(=C1)C=C(C=N2)C(NC3=C(C=C(C(

WY 14643 (Pirinixic Acid) C1(NC2C(=C(C=CC=2)C)C)=NC(=NC(=C1)Cl)SC

Plerixafor (AMD3100) N1(CC2=CC=C(CN3CCCNCCNCCCNCC3)C=C2

NSC 23766 N1(C(=CC(=C2C=C(C=CC=12)NC3=NC(=NC(=C3)C

PRT062607 (P505-15, PRT2607, BIIB057N1(=C(N=C(C(=C1)C(N)=O)NC2=CC(=CC=C2)N

Apremilast (CC-10004) C1=CC2=C(C(N(C2=O)[C@@H](C3=CC(=C(C=C3

VU 0364439 C1=CC=CC(=N1)C(NC2=CC(=C(C=C2)S(=O)(=O)

Butein C1(=C(C=C(C=C1)O)O)C(/C=C/C2=CC(=C(C=C2

Necrostatin-1 C1=CC=C2C(=C1)C(=CN2)CC3NC(N(C3=O)C)=S

UPF 1069 C1=CC(=C2C(=C1)C(NC=C2)=O)OCC(C3=CC=C

GDC-0349 N(C(=O)NC1C=CC(=CC=1)C2N=C3C(=C(N=2)N

GW2580 N1=C(N=CC(=C1N)CC2=CC=C(C(=C2)OC)OCC3

Scriptaid C1=CC=C2C3=C1C(N(C(C(=CC=C2)3)=O)CCCC

ABT-199 (GDC-0199 ) C1=C(C=CC(=C1)C2CC(CCC=2CN3CCN(CC3)C4=

Macitentan C1(=CN=C(N=C1)OCCOC2=C(C(=NC=N2)NS(=O)

Plate Location CAS Number Concentration Molecular Weighta1-L1100-01 923564-51-6 10 mM 974.61 a2-L1100-01 852808-04-9 10 mM 813.43

a3-L1100-01 796967-16-3 10 mM 375.41 a4-L1100-01 912444-00-9 10 mM 244.29

a5-L1100-01 319460-85-0 10 mM 386.47 a6-L1100-01 379231-04-6 10 mM 542.03

a7-L1100-01 808118-40-3 10 mM 352.34 a8-L1100-01 606143-52-6 10 mM 457.68

a9-L1100-01 915019-65-7 10 mM 469.55 a10-L1100-01 656247-17-5 10 mM 539.62

a11-L1100-01 439081-18-2 10 mM 485.94 b1-L1100-01 179324-69-7 10 mM 384.24

b2-L1100-01 380843-75-4 10 mM 530.45 b3-L1100-01 288383-20-0 10 mM 450.51

b4-L1100-01 405169-16-6 10 mM 392.43 b5-L1100-01 267243-28-7 10 mM 485.94

b6-L1100-01 212631-79-3 10 mM 478.67 b7-L1100-01 302962-49-8 10 mM 488.01

b8-L1100-01 572924-54-0 10 mM 990.21 b9-L1100-01 183319-69-9 10 mM 429.90

b10-L1100-01 184475-35-2 10 mM 446.90 b11-L1100-01 220127-57-1 10 mM 589.71

c1-L1100-01 388082-77-7 10 mM 925.46 c2-L1100-01 191732-72-6 10 mM 259.26

c3-L1100-01 857876-30-3 10 mM 569.44 c4-L1100-01 641571-10-0 10 mM 529.52

c5-L1100-01 475489-16-8 10 mM 439.55 c6-L1100-01 635702-64-6 10 mM 473.98

c7-L1100-01 391210-10-9 10 mM 482.19 c8-L1100-01 371935-74-9 10 mM 348.36

c9-L1100-01 53123-88-9 10 mM 914.18 c10-L1100-01 475207-59-1 10 mM 637.03

c11-L1100-01 315702-99-9 10 mM 267.35 d1-L1100-01 341031-54-7 10 mM 532.56

d2-L1100-01 387867-13-2 10 mM 562.70 d3-L1100-01 162635-04-3 10 mM 1030.29

d4-L1100-01 58880-19-6 10 mM 302.40 d5-L1100-01 443913-73-3 10 mM 475.35

d6-L1100-01 149647-78-9 10 mM 264.30 d7-L1100-01 639089-54-6 10 mM 464.59

d8-L1100-01 129830-38-2 10 mM 320.26 d9-L1100-01 488832-69-5 10 mM 400.50

d10-L1100-01 209783-80-2 10 mM 376.41 d11-L1100-01 170364-57-5 10 mM 515.61

e1-L1100-01 714971-09-2 10 mM 567.01 e2-L1100-01 803712-79-0 10 mM 413.49

e3-L1100-01 763113-22-0 10 mM 434.46 e4-L1100-01 890090-75-2 10 mM 581.50

e5-L1100-01 790299-79-5 10 mM 498.64

e6-L1100-01 957054-30-7 10 mM 513.64

e7-L1100-01 305350-87-2 10 mM 335.35 e8-L1100-01 301836-41-9 10 mM 384.39

e9-L1100-01 877399-52-5 10 mM 450.34 e10-L1100-01 747412-49-3 10 mM 465.54

e11-L1100-01 477575-56-7 10 mM 641.61 f1-L1100-01 65673-63-4 10 mM 409.23

f2-L1100-01 475110-96-4 10 mM 417.41 f3-L1100-01 280744-09-4 10 mM 371.22

f4-L1100-01 152121-47-6 10 mM 377.43 f5-L1100-01 152121-30-7 10 mM 331.34

f6-L1100-01 1032350-13-2 10 mM 480.39 f7-L1100-01 183322-45-4 10 mM 396.67

f8-L1100-01 658084-23-2 10 mM 568.09 f9-L1100-01 879085-55-9 10 mM 421.30

f10-L1100-01 649735-46-6 10 mM 370.38 f11-L1100-01 414864-00-9 10 mM 318.35

g1-L1100-01 160003-66-7 10 mM 292.03 g2-L1100-01 475488-23-4 10 mM 453.58

g3-L1100-01 783355-60-2 10 mM 397.42 g4-L1100-01 867160-71-2 10 mM 421.49

g5-L1100-01 587871-26-9 10 mM 395.49 g6-L1100-01 1089283-49-7 10 mM 851.96

g7-L1100-01 956905-27-4 10 mM 372.38 g8-L1100-01 404951-53-7 10 mM 379.46

g9-L1100-01 875320-29-9 10 mM 394.48 g10-L1100-01 957217-65-1 10 mM 431.39

g11-L1100-01 459868-92-9 10 mM 421.36 h1-L1100-01 869363-13-3 10 mM 476.86

h2-L1100-01 212141-51-0 10 mM 419.73 h3-L1100-01 1173097-76-1 10 mM 426.56

h4-L1100-01 331771-20-1 10 mM 513.59 h5-L1100-01 905281-76-7 10 mM 334.37

h6-L1100-01 154447-36-6 10 mM 307.34 h7-L1100-01 742112-33-0 10 mM 460.45

h8-L1100-01 827318-97-8 10 mM 474.55 h9-L1100-01 761439-42-3 10 mM 614.20

h10-L1100-01 755038-02-9 10 mM 521.66 h11-L1100-01 172732-68-2 10 mM 380.39

a1-L1100-02 849217-64-7 10 mM 632.65 a2-L1100-02 1022150-57-7 10 mM 359.41

a3-L1100-02 937174-76-0 10 mM 425.48 a4-L1100-02 943540-75-8 10 mM 377.35

a5-L1100-02 603139-19-1 10 mM 525.56 a6-L1100-02 827022-32-2 10 mM 483.99

a7-L1100-02 35943-35-2 10 mM 320.30 a8-L1100-02 956958-53-5 10 mM 448.52

a9-L1100-02 849217-68-1 10 mM 501.51 a10-L1100-02 159351-69-6 10 mM 958.22

a11-L1100-02 877877-35-5 10 mM 573.70

b1-L1100-02 726169-73-9 10 mM 396.44

b2-L1100-02 154229-19-3 10 mM 349.51 b3-L1100-02 1001645-58-4 10 mM 506.02

b4-L1100-02 781661-94-7 10 mM 443.29 b5-L1100-02 3544-24-9 10 mM 136.15

b6-L1100-02 1028486-01-2 10 mM 518.92 b7-L1100-02 896466-04-9 10 mM 381.43

b8-L1100-02 150399-23-8 10 mM 471.37 b9-L1100-02 649735-63-7 10 mM 441.46

b10-L1100-02 850173-95-4 10 mM 428.95 b11-L1100-02 401900-40-1 10 mM 441.36

c1-L1100-02 75747-14-7 10 mM 585.69 c2-L1100-02 467214-21-7 10 mM 653.21

c3-L1100-02 133550-30-8 10 mM 294.30 c4-L1100-02 873054-44-5 10 mM 392.49

c5-L1100-02 345627-80-7 10 mM 380.53 c6-L1100-02 4449-51-8 10 mM 411.62

c7-L1100-02 722544-51-6 10 mM 507.56 c8-L1100-02 114977-28-5 10 mM 807.88

c9-L1100-02 122111-03-9 10 mM 299.66 c10-L1100-02 33069-62-4 10 mM 853.91

c11-L1100-02 918505-84-7 10 mM 413.83 d1-L1100-02 186692-46-6 10 mM 354.45

d2-L1100-02 1146618-41-8 10 mM 527.04 d3-L1100-02 501919-59-1 10 mM 365.36

d4-L1100-02 154361-50-9 10 mM 359.35 d5-L1100-02 1030612-90-8 10 mM 467.25

d6-L1100-02 888216-25-9 10 mM 364.40 d7-L1100-02 289905-88-0 10 mM 344.84

d8-L1100-02 912999-49-6 10 mM 409.52 d9-L1100-02 417716-92-8 10 mM 426.85

d10-L1100-02 141430-65-1 10 mM 371.41 d11-L1100-02 15663-27-1 10 mM 300.05

e1-L1100-02 537705-08-1 10 mM 469.53 e2-L1100-02 1069-66-5 10 mM 166.19

e3-L1100-02 663619-89-4 10 mM 364.44 e4-L1100-02 1214265-56-1 10 mM 464.95

e5-L1100-02 693228-63-6 10 mM 368.46 e6-L1100-02 881202-45-5 10 mM 328.41

e7-L1100-02 1213269-23-8 10 mM 494.18 e8-L1100-02 841205-47-8 10 mM 389.33

e9-L1100-02 848695-25-0 10 mM 318.76 e10-L1100-02 167869-21-8 10 mM 267.28

e11-L1100-02 755037-03-7 10 mM 482.82 f1-L1100-02 1214265-57-2 10 mM 481.01

f2-L1100-02 284028-89-3 10 mM 312.31 f3-L1100-02 934353-76-1 10 mM 375.47

f4-L1100-02 850876-88-9 10 mM 731.83 f5-L1100-02 155213-67-5 10 mM 720.94

f6-L1100-02 321674-73-1 10 mM 331.36

f7-L1100-02 677338-12-4 10 mM 351.36

f8-L1100-02 120511-73-1 10 mM 293.37 f9-L1100-02 170729-80-3 10 mM 534.43

f10-L1100-02 90357-06-5 10 mM 430.37 f11-L1100-02 129453-61-8 10 mM 606.77

g1-L1100-02 112887-68-0 10 mM 458.49 g2-L1100-02 50-35-1 10 mM 258.23

g3-L1100-02 1012054-59-9 10 mM 434.49 g4-L1100-02 426219-18-3 10 mM 307.35

g5-L1100-02 107868-30-4 10 mM 296.40 g6-L1100-02 98319-26-7 10 mM 372.54

g7-L1100-02 97682-44-5 10 mM 586.68 g8-L1100-02 4291-63-8 10 mM 285.69

g9-L1100-02 2353-33-5 10 mM 228.21 g10-L1100-02 16208-51-8 10 mM 326.34

g11-L1100-02 164656-23-9 10 mM 528.53 h1-L1100-02 372196-77-5 10 mM 488.74

h2-L1100-02 104344-23-2 10 mM 441.52 h3-L1100-02 475108-18-0 10 mM 454.86

h4-L1100-02 25316-40-9 10 mM 579.98 h5-L1100-02 51-21-8 10 mM 130.08

h6-L1100-02 59-05-2 10 mM 454.44 h7-L1100-02 3543-75-7 10 mM 394.72

h8-L1100-02 121032-29-9 10 mM 297.27 h9-L1100-02 9041-93-4 10 mM 1512.62

h10-L1100-02 41575-94-4 10 mM 371.25 h11-L1100-02 1403764-72-6 10 mM 347.39

a1-L1100-03 50-18-0 10 mM 261.09 a2-L1100-03 123318-82-1 10 mM 303.68

a3-L1100-03 371942-69-7 10 mM 467.48 a4-L1100-03 728033-96-3 10 mM 443.44

a5-L1100-03 4342-03-4 10 mM 182.18 a6-L1100-03 56390-09-1 10 mM 579.98

a7-L1100-03 61825-94-3 10 mM 397.29 a8-L1100-03 33419-42-0 10 mM 588.56

a9-L1100-03 938440-64-3 10 mM 465.54 a10-L1100-03 82640-04-8 10 mM 510.04

a11-L1100-03 57852-57-0 10 mM 533.95 b1-L1100-03 75607-67-9 10 mM 365.21

b2-L1100-03 119413-54-6 10 mM 457.91 b3-L1100-03 362-07-2 10 mM 302.41

b4-L1100-03 65678-07-1 10 mM 305.17 b5-L1100-03 112809-51-5 10 mM 285.30

b6-L1100-03 85622-93-1 10 mM 194.15 b7-L1100-03 2068-78-2 10 mM 923.04

b8-L1100-03 138112-76-2 10 mM 243.30 b9-L1100-03 850879-09-3 10 mM 447.51

b10-L1100-03 57-22-7 10 mM 824.96 b11-L1100-03 443797-96-4 10 mM 394.36

c1-L1100-03 915087-33-1 10 mM 464.44

c2-L1100-03 65928-58-7 10 mM 311.42

c3-L1100-03 106308-44-5 10 mM 238.19 c4-L1100-03 171228-49-2 10 mM 700.78

c5-L1100-03 150322-43-3 10 mM 373.44 c6-L1100-03 196597-26-9 10 mM 259.34

c7-L1100-03 364782-34-3 10 mM 393.87 c8-L1100-03 169590-42-5 10 mM 381.37

c9-L1100-03 1146699-66-2 10 mM 520.88 c10-L1100-03 219580-11-7 10 mM 523.67

c11-L1100-03 1062169-56-5 10 mM 495.53 d1-L1100-03 918504-65-1 10 mM 489.92

d2-L1100-03 371242-69-2 10 mM 397.43 d3-L1100-03 702675-74-9 10 mM 591.47

d4-L1100-03 702674-56-4 10 mM 471.35 d5-L1100-03 71675-85-9 10 mM 369.48

d6-L1100-03 72432-10-1 10 mM 219.24 d7-L1100-03 85650-56-2 10 mM 401.84

d8-L1100-03 86541-74-4 10 mM 460.95 d9-L1100-03 1235-82-1 10 mM 347.92

d10-L1100-03 7689-03-4 10 mM 348.35 d11-L1100-03 61422-45-5 10 mM 257.26

e1-L1100-03 34157-83-0 10 mM 450.61 e2-L1100-03 83881-52-1 10 mM 461.81

e3-L1100-03 132203-70-4 10 mM 492.52 e4-L1100-03 73963-72-1 10 mM 369.46

e5-L1100-03 152044-53-6 10 mM 493.66 e6-L1100-03 50-91-9 10 mM 246.19

e7-L1100-03 17902-23-7 10 mM 200.17 e8-L1100-03 3778-73-2 10 mM 261.09

e9-L1100-03 595-33-5 10 mM 384.51 e10-L1100-03 50-44-2 10 mM 152.18

e11-L1100-03 118072-93-8 10 mM 272.09 f1-L1100-03 355025-24-0 10 mM 474.96

f2-L1100-03 1002304-34-8 10 mM 383.40 f3-L1100-03 553-21-9 10 mM 232.32

f4-L1100-03 50-02-2 10 mM 392.46 f5-L1100-03 77883-43-3 10 mM 547.58

f6-L1100-03 476-66-4 10 mM 302.19 f7-L1100-03 41340-25-4 10 mM 287.35

f8-L1100-03 33125-97-2 10 mM 244.29 f9-L1100-03 78755-81-4 10 mM 303.29

f10-L1100-03 56296-78-7 10 mM 345.79 f11-L1100-03 75507-68-5 10 mM 420.39

g1-L1100-03 61718-82-9 10 mM 434.41 g2-L1100-03 60142-95-2 10 mM 207.70

g3-L1100-03 1953-04-4 10 mM 368.27 g4-L1100-03 446-72-0 10 mM 270.24

g5-L1100-03 93479-97-1 10 mM 490.62 g6-L1100-03 107007-99-8 10 mM 348.87

g7-L1100-03 677297-51-7 10 mM 346.34

g8-L1100-03 65277-42-1 10 mM 531.43

g9-L1100-03 103577-45-3 10 mM 369.36 g10-L1100-03 137-58-6 10 mM 234.34

g11-L1100-03 79794-75-5 10 mM 382.88 h1-L1100-03 124750-99-8 10 mM 462.01

h2-L1100-03 958852-01-2 10 mM 333.36 h3-L1100-03 875337-44-3 10 mM 517.60

h4-L1100-03 1225497-78-8 10 mM 473.47 h5-L1100-03 228559-41-9 10 mM 469.41

h6-L1100-03 152044-54-7 10 mM 507.68 h7-L1100-03 729607-74-3 10 mM 410.42

h8-L1100-03 69408-81-7 10 mM 283.33 h9-L1100-03 130693-82-2 10 mM 360.90

h10-L1100-03 60282-87-3 10 mM 310.43 h11-L1100-03 67392-87-4 10 mM 366.49

a1-L1100-04 941678-49-5 10 mM 306.37 a2-L1100-04 4759-48-2 10 mM 300.44

a3-L1100-04 192725-17-0 10 mM 628.80 a4-L1100-04 21535-47-7 10 mM 300.83

a5-L1100-04 38304-91-5 10 mM 209.25 a6-L1100-04 50924-49-7 10 mM 259.22

a7-L1100-04 112885-42-4 10 mM 614.02 a8-L1100-04 82956-11-4 10 mM 539.58

a9-L1100-04 57149-08-3 10 mM 465.41 a10-L1100-04 73590-58-6 10 mM 345.42

a11-L1100-04 99614-01-4 10 mM 329.82 b1-L1100-04 28721-07-5 10 mM 252.27

b2-L1100-04 257933-82-7 10 mM 467.92 b3-L1100-04 501-36-0 10 mM 228.24

b4-L1100-04 119302-91-9 10 mM 609.68 b5-L1100-04 3056-17-5 10 mM 224.21

b6-L1100-04 202138-50-9 10 mM 635.51 b7-L1100-04 147127-20-6 10 mM 287.21

b8-L1100-04 13647-35-3 10 mM 329.43 b9-L1100-04 81403-68-1 10 mM 425.91

b10-L1100-04 648450-29-7 10 mM 257.27 b11-L1100-04 120202-66-6 10 mM 419.90

c1-L1100-04 62996-74-1 10 mM 466.53 c2-L1100-04 99873-43-5 10 mM 243.69

c3-L1100-04 95635-56-6 10 mM 500.46 c4-L1100-04 135062-02-1 10 mM 452.59

c5-L1100-04 61413-54-5 10 mM 275.34 c6-L1100-04 171599-83-0 10 mM 666.70

c7-L1100-04 103628-48-4 10 mM 413.49 c8-L1100-04 30123-17-2 10 mM 458.93

c9-L1100-04 64461-82-1 10 mM 290.17 c10-L1100-04 97240-79-4 10 mM 339.36

c11-L1100-04 375815-87-5 10 mM 361.35 d1-L1100-04 99300-78-4 10 mM 313.86

d2-L1100-04 137234-62-9 10 mM 349.31

d3-L1100-04 111406-87-2 10 mM 236.29

d4-L1100-04 1158838-45-9 10 mM 588.07 d5-L1100-04 336113-53-2 10 mM 517.06

d6-L1100-04 192185-72-1 10 mM 489.40 d7-L1100-04 398493-79-3 10 mM 501.62

d8-L1100-04 153259-65-5 10 mM 343.42 d9-L1100-04 186497-07-4 10 mM 424.43

d10-L1100-04 229975-97-7 10 mM 802.93 d11-L1100-04 1226056-71-8 10 mM 311.36

e1-L1100-04 129-56-6 10 mM 220.23 e2-L1100-04 82419-36-1 10 mM 361.37

e3-L1100-04 186826-86-8 10 mM 437.89 e4-L1100-04 41294-56-8 10 mM 400.64

e5-L1100-04 252916-29-3 10 mM 310.35 e6-L1100-04 202825-46-5 10 mM 398.45

e7-L1100-04 864082-47-3 10 mM 432.37 e8-L1100-04 1236699-92-5 10 mM 431.20

e9-L1100-04 356559-20-1 10 mM 343.42 e10-L1100-04 579-13-5 10 mM 791.06

e11-L1100-04 1026785-55-6 10 mM 445.61 f1-L1100-04 167465-36-3 10 mM 636.99

f2-L1100-04 1009119-64-5 10 mM 738.88 f3-L1100-04 852475-26-4 10 mM 314.31

f4-L1100-04 173529-46-9 10 mM 424.47 f5-L1100-04 497839-62-0 10 mM 440.58

f6-L1100-04 718630-59-2 10 mM 361.48 f7-L1100-04 143388-64-1 10 mM 371.93

f8-L1100-04 593960-11-3 10 mM 389.88 f9-L1100-04 943319-70-8 10 mM 532.56

f10-L1100-04 21679-14-1 10 mM 285.23 f11-L1100-04 862507-23-1 10 mM 612.74

g1-L1100-04 146464-95-1 10 mM 477.47 g2-L1100-04 847559-80-2 10 mM 480.41

g3-L1100-04 128794-94-5 10 mM 433.49 g4-L1100-04 479-18-5 10 mM 254.24

g5-L1100-04 107133-36-8 10 mM 441.60 g6-L1100-04 138402-11-6 10 mM 428.53

g7-L1100-04 171596-29-5 10 mM 389.40 g8-L1100-04 929016-96-6 10 mM 358.48

g9-L1100-04 57469-77-9 10 mM 352.47 g10-L1100-04 942947-93-5 10 mM 497.02

g11-L1100-04 238750-77-1 10 mM 406.47 h1-L1100-04 1349796-36-6 10 mM 599.66

h2-L1100-04 844442-38-2 10 mM 382.24 h3-L1100-04 955365-80-7 10 mM 500.60

h4-L1100-04 950769-58-1 10 mM 560.67 h5-L1100-04 1194044-20-6 10 mM 320.36

h6-L1100-04 422513-13-1 10 mM 516.65 h7-L1100-04 1094614-84-2 10 mM 426.51

h8-L1100-04 1094614-85-3 10 mM 440.54

h9-L1100-04 860352-01-8 10 mM 362.42

h10-L1100-04 841290-80-0 10 mM 470.45 h11-L1100-04 343787-29-1 10 mM 417.50

a1-L1100-05 117570-53-3 10 mM 282.29 a2-L1100-05 402957-28-2 10 mM 679.85

a3-L1100-05 361442-04-8 10 mM 315.41 a4-L1100-05 49843-98-3 10 mM 248.71

a5-L1100-05 444912-48-5 10 mM 503.33 a6-L1100-05 288150-92-5 10 mM 356.37

a7-L1100-05 461432-26-8 10 mM 408.87 a8-L1100-05 152520-56-4 10 mM 441.90

a9-L1100-05 74150-27-9 10 mM 334.37 a10-L1100-05 1009298-09-2 10 mM 465.54

a11-L1100-05 1191951-57-1 10 mM 409.61 b1-L1100-05 286370-15-8 10 mM 416.86

b2-L1100-05 857531-00-1 10 mM 337.85 b3-L1100-05 1025720-94-8 10 mM 512.89

b4-L1100-05 936727-05-8 10 mM 452.41 b5-L1100-05 19171-19-8 10 mM 273.24

b6-L1100-05 391210-00-7 10 mM 561.09 b7-L1100-05 925701-49-1 10 mM 547.67

b8-L1100-05 1397219-81-6 10 mM 416.99 b9-L1100-05 105628-07-7 10 mM 327.83

b10-L1100-05 285983-48-4 10 mM 527.66 b11-L1100-05 948557-43-5 10 mM 439.53

c1-L1100-05 139481-59-7 10 mM 440.45 c2-L1100-05 827022-33-3 10 mM 573.66

c3-L1100-05 130964-39-5 10 mM 519.28 c4-L1100-05 601514-19-6 10 mM 318.33

c5-L1100-05 58970-76-6 10 mM 308.37 c6-L1100-05 503612-47-3 10 mM 459.50

c7-L1100-05 425386-60-3 10 mM 361.44 c8-L1100-05 144689-63-4 10 mM 558.59

c9-L1100-05 145202-66-0 10 mM 391.47 c10-L1100-05 101-26-8 10 mM 261.12

c11-L1100-05 62893-19-0 10 mM 645.67 d1-L1100-05 160970-54-7 10 mM 495.53

d2-L1100-05 1744-22-5 10 mM 234.20 d3-L1100-05 106266-06-2 10 mM 410.48

d4-L1100-05 616-91-1 10 mM 163.19 d5-L1100-05 121268-17-5 10 mM 326.13

d6-L1100-05 26159-34-2 10 mM 252.24 d7-L1100-05 55981-09-4 10 mM 307.28

d8-L1100-05 96829-58-2 10 mM 495.73 d9-L1100-05 315-30-0 10 mM 136.11

d10-L1100-05 17795-21-0 10 mM 159.10 d11-L1100-05 107753-78-6 10 mM 575.68

e1-L1100-05 15687-27-1 10 mM 206.28 e2-L1100-05 161814-49-9 10 mM 505.63

e3-L1100-05 555-30-6 10 mM 211.21

e4-L1100-05 22071-15-4 10 mM 254.28

e5-L1100-05 74103-07-4 10 mM 376.40 e6-L1100-05 147-94-4 10 mM 243.22

e7-L1100-05 139264-17-8 10 mM 287.36 e8-L1100-05 84680-54-6 10 mM 348.40

e9-L1100-05 75695-93-1 10 mM 371.39 e10-L1100-05 53-16-7 10 mM 270.37

e11-L1100-05 2022-85-7 10 mM 129.09 f1-L1100-05 125-84-8 10 mM 232.28

f2-L1100-05 317-34-0 10 mM 420.43 f3-L1100-05 298-46-4 10 mM 236.27

f4-L1100-05 56211-40-6 10 mM 348.42 f5-L1100-05 69655-05-6 10 mM 236.23

f6-L1100-05 76584-70-8 10 mM 310.41 f7-L1100-05 143491-57-0 10 mM 247.25

f8-L1100-05 134678-17-4 10 mM 229.26 f9-L1100-05 107724-20-9 10 mM 414.49

f10-L1100-05 36322-90-4 10 mM 331.35 f11-L1100-05 95058-81-4 10 mM 263.20

g1-L1100-05 142340-99-6 10 mM 501.47 g2-L1100-05 7481-89-2 10 mM 211.22

g3-L1100-05 144598-75-4 10 mM 426.48 g4-L1100-05 144701-48-4 10 mM 514.62

g5-L1100-05 129618-40-2 10 mM 266.30 g6-L1100-05 161973-10-0 10 mM 713.12

g7-L1100-05 66085-59-4 10 mM 418.44 g8-L1100-05 63675-72-9 10 mM 388.41

g9-L1100-05 5633-20-5 10 mM 357.49 g10-L1100-05 111974-72-2 10 mM 883.09

g11-L1100-05 113-59-7 10 mM 315.86 h1-L1100-05 154-42-7 10 mM 167.19

h2-L1100-05 89778-27-8 10 mM 598.08 h3-L1100-05 320-67-2 10 mM 244.20

h4-L1100-05 1405-89-6 10 mM 1486.07 h5-L1100-05 79902-63-9 10 mM 418.57

h6-L1100-05 87333-19-5 10 mM 416.51 h7-L1100-05 66357-59-3 10 mM 350.86

h8-L1100-05 2627-69-2 10 mM 258.23 h9-L1100-05 60-31-1 10 mM 181.66

h10-L1100-05 21829-25-4 10 mM 346.33 h11-L1100-05 111470-99-6 10 mM 567.05

a1-L1100-06 113-92-8 10 mM 390.86 a2-L1100-06 63659-19-8 10 mM 343.89

a3-L1100-06 5875-06-9 10 mM 330.85 a4-L1100-06 103177-37-3 10 mM 481.50

a5-L1100-06 72956-09-3 10 mM 406.47 a6-L1100-06 64872-77-1 10 mM 474.79

a7-L1100-06 83905-01-5 10 mM 748.98 a8-L1100-06 31430-15-6 10 mM 313.28

a9-L1100-06 13010-47-4 10 mM 233.70

a10-L1100-06 51481-61-9 10 mM 252.34

a11-L1100-06 14976-57-9 10 mM 459.96 b1-L1100-06 60628-96-8 10 mM 310.39

b2-L1100-06 392-17-7 10 mM 684.81 b3-L1100-06 2809-21-4 10 mM 206.03

b4-L1100-06 129938-20-1 10 mM 341.87 b5-L1100-06 1197-18-8 10 mM 157.21

b6-L1100-06 93793-83-0 10 mM 384.90 b7-L1100-06 72509-76-3 10 mM 384.25

b8-L1100-06 76963-41-2 10 mM 331.46 b9-L1100-06 28860-95-9 10 mM 226.23

b10-L1100-06 137862-53-4 10 mM 435.52 b11-L1100-06 105826-92-4 10 mM 320.81

c1-L1100-06 15307-79-6 10 mM 318.13 c2-L1100-06 88150-42-9 10 mM 408.88

c3-L1100-06 13311-84-7 10 mM 276.21 c4-L1100-06 93957-55-2 10 mM 433.45

c5-L1100-06 1508-75-4 10 mM 284.35 c6-L1100-06 145-13-1 10 mM 316.48

c7-L1100-06 723-46-6 10 mM 253.28 c8-L1100-06 57381-26-7 10 mM 256.09

c9-L1100-06 76095-16-4 10 mM 492.52 c10-L1100-06 1115-70-4 10 mM 165.62

c11-L1100-06 13710-19-5 10 mM 261.70 d1-L1100-06 52549-17-4 10 mM 255.27

d2-L1100-06 77191-36-7 10 mM 246.30 d3-L1100-06 65141-46-0 10 mM 211.17

d4-L1100-06 54965-24-1 10 mM 563.64 d5-L1100-06 6284-40-8 10 mM 195.21

d6-L1100-06 129722-12-9 10 mM 448.39 d7-L1100-06 155-41-9 10 mM 398.29

d8-L1100-06 19774-82-4 10 mM 681.77 d9-L1100-06 73-24-5 10 mM 135.13

d10-L1100-06 321-30-2 10 mM 368.33 d11-L1100-06 2922-28-3 10 mM 171.59

e1-L1100-06 53885-35-1 10 mM 300.25 e2-L1100-06 103890-78-4 10 mM 455.54

e3-L1100-06 366-70-1 10 mM 257.76 e4-L1100-06 99614-02-5 10 mM 293.36

e5-L1100-06 13721-39-6 10 mM 183.91 e6-L1100-06 697761-98-1 10 mM 447.88

e7-L1100-06 376348-65-1 10 mM 513.67 e8-L1100-06 518048-05-0 10 mM 444.42

e9-L1100-06 58-14-0 10 mM 248.71 e10-L1100-06 191217-81-9 10 mM 302.26

e11-L1100-06 950762-95-5 10 mM 296.32 f1-L1100-06 869288-64-2 10 mM 491.49

f2-L1100-06 582315-72-8 10 mM 345.34 f3-L1100-06 94055-76-2 10 mM 499.64

f4-L1100-06 1291074-87-7 10 mM 525.56

f5-L1100-06 43229-80-7 10 mM 402.40

f6-L1100-06 34580-14-8 10 mM 425.50 f7-L1100-06 64887-14-5 10 mM 423.94

f8-L1100-06 15291-75-5 10 mM 408.40 f9-L1100-06 58-96-8 10 mM 244.20

f10-L1100-06 30484-77-6 10 mM 477.42 f11-L1100-06 90098-04-7 10 mM 370.79

g1-L1100-06 82159-09-9 10 mM 319.40 g2-L1100-06 145040-37-5 10 mM 610.66

g3-L1100-06 65-28-1 10 mM 377.46 g4-L1100-06 51803-78-2 10 mM 308.31

g5-L1100-06 427-51-0 10 mM 416.94 g6-L1100-06 41100-52-1 10 mM 215.76

g7-L1100-06 969-33-5 10 mM 323.86 g8-L1100-06 3094-09-5 10 mM 246.19

g9-L1100-06 112529-15-4 10 mM 392.90 g10-L1100-06 70374-39-9 10 mM 371.82

g11-L1100-06 135459-87-9 10 mM 513.49 h1-L1100-06 62571-86-2 10 mM 217.29

h2-L1100-06 4682-36-4 10 mM 461.50 h3-L1100-06 103766-25-2 10 mM 145.54

h4-L1100-06 70024-40-7 10 mM 459.92 h5-L1100-06 75330-75-5 10 mM 404.54

h6-L1100-06 118288-08-7 10 mM 431.55 h7-L1100-06 75438-57-2 10 mM 241.68

h8-L1100-06 78712-43-3 10 mM 264.71 h9-L1100-06 145525-41-3 10 mM 668.88

h10-L1100-06 302543-62-0 10 mM 393.89 h11-L1100-06 83915-83-7 10 mM 405.49

a1-L1100-07 134523-03-8 10 mM 1155.34 a2-L1100-07 76824-35-6 10 mM 337.45

a3-L1100-07 82586-52-5 10 mM 535.03 a4-L1100-07 167221-71-8 10 mM 456.32

a5-L1100-07 92077-78-6 10 mM 435.51 a6-L1100-07 50-42-0 10 mM 347.88

a7-L1100-07 136434-34-9 10 mM 333.88 a8-L1100-07 39133-31-8 10 mM 387.47

a9-L1100-07 148849-67-6 10 mM 505.05 a10-L1100-07 129101-54-8 10 mM 400.42

a11-L1100-07 145108-58-3 10 mM 236.74 b1-L1100-07 659-18-7 10 mM 307.43

b2-L1100-07 90038-01-0 10 mM 222.71 b3-L1100-07 88889-14-9 10 mM 585.64

b4-L1100-07 181183-52-8 10 mM 469.55 b5-L1100-07 177036-94-1 10 mM 378.42

b6-L1100-07 153559-49-0 10 mM 348.00 b7-L1100-07 110221-44-8 10 mM 513.07

b8-L1100-07 56974-61-9 10 mM 417.48 b9-L1100-07 161735-79-1 10 mM 267.34

b10-L1100-07 16676-29-2 10 mM 377.86

b11-L1100-07 23672-07-3 10 mM 341.43

c1-L1100-07 123040-16-4 10 mM 386.27 c2-L1100-07 108612-45-9 10 mM 432.49

c3-L1100-07 42461-84-7 10 mM 491.46 c4-L1100-07 42971-09-5 10 mM 350.45

c5-L1100-07 231277-92-2 10 mM 581.06 c6-L1100-07 132810-10-7 10 mM 367.50

c7-L1100-07 96946-42-8 10 mM 1243.48 c8-L1100-07 122647-32-9 10 mM 885.23

c9-L1100-07 57149-07-2 10 mM 392.49 c10-L1100-07 85416-73-5 10 mM 275.34

c11-L1100-07 198480-56-7 10 mM 507.06 d1-L1100-07 5908-99-6 10 mM 694.83

d2-L1100-07 162401-32-3 10 mM 403.21 d3-L1100-07 60142-96-3 10 mM 171.24

d4-L1100-07 869357-68-6 10 mM 461.23 d5-L1100-07 1032823-75-8 10 mM 456.56

d6-L1100-07 698387-09-6 10 mM 557.04 d7-L1100-07 956697-53-3 10 mM 485.50

d8-L1100-07 124431-80-7 10 mM 535.98 d9-L1100-07 211915-06-9 10 mM 627.73

d10-L1100-07 1234703-40-2 10 mM 559.81 d11-L1100-07 1262036-50-9 10 mM 390.41

e1-L1100-07 1258861-20-9 10 mM 512.50 e2-L1100-07 1000669-72-6 10 mM 332.40

e3-L1100-07 161715-24-8 10 mM 497.63 e4-L1100-07 1255517-76-0 10 mM 390.41

e5-L1100-07 112960-16-4 10 mM 285.77 e6-L1100-07 147098-20-2 10 mM 500.57

e7-L1100-07 732302-99-7 10 mM 475.97 e8-L1100-07 328543-09-5 10 mM 320.39

e9-L1100-07 1229236-86-5 10 mM 469.94 e10-L1100-07 1072833-77-2 10 mM 361.03

e11-L1100-07 1201902-80-8 10 mM 517.12 f1-L1100-07 940929-33-9 10 mM 553.52

f2-L1100-07 872511-34-7 10 mM 560.48 f3-L1100-07 1050500-29-2 10 mM 621.08

f4-L1100-07 694433-59-5 10 mM 335.40 f5-L1100-07 166518-60-1 10 mM 501.72

f6-L1100-07 848942-61-0 10 mM 473.93 f7-L1100-07 929095-18-1 10 mM 543.60

f8-L1100-07 841290-81-1 10 mM 628.63 f9-L1100-07 1025065-69-3 10 mM 405.42

f10-L1100-07 173334-58-2 10 mM 609.83 f11-L1100-07 1174046-72-0 10 mM 468.84

g1-L1100-07 940310-85-0 10 mM 503.48 g2-L1100-07 183320-51-6 10 mM 415.87

g3-L1100-07 1025687-58-4 10 mM 624.42 g4-L1100-07 900185-01-5 10 mM 397.43

g5-L1100-07 566-48-3 10 mM 302.41

g6-L1100-07 1201898-17-0 10 mM 967.02

g7-L1100-07 905586-69-8 10 mM 354.36 g8-L1100-07 208255-80-5 10 mM 432.46

g9-L1100-07 366017-09-6 10 mM 468.47 g10-L1100-07 136572-09-3 10 mM 677.18

g11-L1100-07 1092351-67-1 10 mM 308.34 h1-L1100-07 1056634-68-4 10 mM 414.46

h2-L1100-07 405554-55-4 10 mM 453.54 h3-L1100-07 811803-05-1 10 mM 493.58

h4-L1100-07 901-47-3 10 mM 342.41 h5-L1100-07 870281-82-6 10 mM 415.42

h6-L1100-07 900185-02-6 10 mM 489.53 h7-L1100-07 496775-61-2 10 mM 442.47

h8-L1100-07 700874-72-2 10 mM 369.42 h9-L1100-07 332012-40-5 10 mM 409.83

h10-L1100-07 74050-98-9 10 mM 395.43 h11-L1100-07 161796-78-7 10 mM 367.40

a1-L1100-08 755038-65-4 10 mM 618.81 a2-L1100-08 914913-88-5 10 mM 406.43

a3-L1100-08 286930-03-8 10 mM 527.65 a4-L1100-08 856243-80-6 10 mM 384.27

a5-L1100-08 935881-37-1 10 mM 312.36 a6-L1100-08 1080622-86-1 10 mM 349.35

a7-L1100-08 154229-18-2 10 mM 391.55 a8-L1100-08 944396-07-0 10 mM 410.39

a9-L1100-08 1009820-21-6 10 mM 349.77 a10-L1100-08 102518-79-6 10 mM 242.32

a11-L1100-08 90-33-5 10 mM 176.17 b1-L1100-08 481-72-1 10 mM 270.24

b2-L1100-08 520-36-5 10 mM 270.24 b3-L1100-08 497-76-7 10 mM 272.25

b4-L1100-08 88495-63-0 10 mM 384.42 b5-L1100-08 464-92-6 10 mM 488.70

b6-L1100-08 491-67-8 10 mM 270.24 b7-L1100-08 21967-41-9 10 mM 446.36

b8-L1100-08 35825-57-1 10 mM 296.36 b9-L1100-08 485-35-8 10 mM 190.24

b10-L1100-08 520-33-2 10 mM 302.27 b11-L1100-08 35354-74-6 10 mM 266.33

c1-L1100-08 489-32-7 10 mM 676.66 c2-L1100-08 491-70-3 10 mM 286.24

c3-L1100-08 519-02-8 10 mM 248.36 c4-L1100-08 13241-33-3 10 mM 610.56

c5-L1100-08 20554-84-1 10 mM 248.32 c6-L1100-08 3681-99-0 10 mM 432.38

c7-L1100-08 53003-10-4 10 mM 751.00 c8-L1100-08 94-07-5 10 mM 167.21

c9-L1100-08 56-69-9 10 mM 220.22 c10-L1100-08 1415-73-2 10 mM 418.39

c11-L1100-08 19057-60-4 10 mM 869.04

d1-L1100-08 479-41-4 10 mM 262.26

d2-L1100-08 117-39-5 10 mM 302.24 d3-L1100-08 480-41-1 10 mM 272.25

d4-L1100-08 10338-51-9 10 mM 300.30 d5-L1100-08 67920-52-9 10 mM 220.15

d6-L1100-08 518-34-3 10 mM 622.75 d7-L1100-08 481-74-3 10 mM 254.24

d8-L1100-08 83207-58-3 10 mM 784.97 d9-L1100-08 5289-74-7 10 mM 480.63

d10-L1100-08 19685-09-7 10 mM 364.35 d11-L1100-08 498-02-2 10 mM 166.17

e1-L1100-08 483-14-7 10 mM 355.43 e2-L1100-08 5985-28-4 10 mM 203.67

e3-L1100-08 64-77-7 10 mM 270.35 e4-L1100-08 66575-29-9 10 mM 410.50

e5-L1100-08 531-95-3 10 mM 242.27 e6-L1100-08 665-66-7 10 mM 187.70

e7-L1100-08 31677-93-7 10 mM 276.20 e8-L1100-08 14919-77-8 10 mM 293.70

e9-L1100-08 18010-40-7 10 mM 324.89 e10-L1100-08 590-63-6 10 mM 196.68

e11-L1100-08 69-09-0 10 mM 355.33 f1-L1100-08 4205-91-8 10 mM 266.50

f2-L1100-08 5786-21-0 10 mM 326.82 f3-L1100-08 104632-26-0 10 mM 211.33

f4-L1100-08 57808-66-9 10 mM 425.91 f5-L1100-08 120011-70-3 10 mM 416.00

f6-L1100-08 50-27-1 10 mM 288.39 f7-L1100-08 67-73-2 10 mM 452.50

f8-L1100-08 65-29-2 10 mM 891.53 f9-L1100-08 84-16-2 10 mM 270.37

f10-L1100-08 152459-95-5 10 mM 493.60 f11-L1100-08 34552-83-5 10 mM 513.50

g1-L1100-08 89226-50-6 10 mM 610.70 g2-L1100-08 89226-75-5 10 mM 683.62

g3-L1100-08 78415-72-2 10 mM 211.22 g4-L1100-08 70476-82-3 10 mM 517.40

g5-L1100-08 105816-04-4 10 mM 317.42 g6-L1100-08 114-80-7 10 mM 303.20

g7-L1100-08 39562-70-4 10 mM 360.37 g8-L1100-08 132539-06-1 10 mM 312.44

g9-L1100-08 140462-76-6 10 mM 373.87 g10-L1100-08 2315-02-8 10 mM 296.84

g11-L1100-08 82571-53-7 10 mM 228.25 h1-L1100-08 15500-66-0 10 mM 732.67

h2-L1100-08 63-92-3 10 mM 340.30 h3-L1100-08 34183-22-7 10 mM 377.90

h4-L1100-08 81110-73-8 10 mM 385.48 h5-L1100-08 155141-29-0 10 mM 473.50

h6-L1100-08 51022-70-9 10 mM 337.39

h7-L1100-08 114-49-8 10 mM 384.26

h8-L1100-08 959-24-0 10 mM 308.82 h9-L1100-08 2447-57-6 10 mM 310.33

h10-L1100-08 59804-37-4 10 mM 337.38 h11-L1100-08 224785-90-4 10 mM 579.11

a1-L1100-09 23076-35-9 10 mM 256.79 a2-L1100-09 10347-81-6 10 mM 313.86

a3-L1100-09 550-99-2 10 mM 246.74 a4-L1100-09 51-42-3 10 mM 333.29

a5-L1100-09 51-43-4 10 mM 183.20 a6-L1100-09 329-65-7 10 mM 183.20

a7-L1100-09 630-93-3 10 mM 274.25 a8-L1100-09 57-41-0 10 mM 252.27

a9-L1100-09 72-48-0 10 mM 240.21 a10-L1100-09 62-31-7 10 mM 189.64

a11-L1100-09 4460-86-0 10 mM 196.20 b1-L1100-09 23239-51-2 10 mM 323.81

b2-L1100-09 17321-77-6 10 mM 351.31 b3-L1100-09 834-28-6 10 mM 241.72

b4-L1100-09 498-45-3 10 mM 155.19 b5-L1100-09 139404-48-1 10 mM 490.43

b6-L1100-09 85700-55-6 10 mM 191.66 b7-L1100-09 10405-02-4 10 mM 427.96

b8-L1100-09 124937-52-6 10 mM 475.57 b9-L1100-09 79307-93-0 10 mM 418.36

b10-L1100-09 486-35-1 10 mM 178.14 b11-L1100-09 81103-11-9 10 mM 747.95

c1-L1100-09 122320-73-4 10 mM 357.43 c2-L1100-09 17440-83-4 10 mM 302.12

c3-L1100-09 50-41-9 10 mM 598.08 c4-L1100-09 304-20-1 10 mM 196.64

c5-L1100-09 51-30-9 10 mM 247.72 c6-L1100-09 71-58-9 10 mM 386.52

c7-L1100-09 61-76-7 10 mM 203.67 c8-L1100-09 136-47-0 10 mM 300.82

c9-L1100-09 62-44-2 10 mM 179.22 c10-L1100-09 30516-87-1 10 mM 267.24

c11-L1100-09 82586-55-8 10 mM 474.98 d1-L1100-09 25332-39-2 10 mM 408.32

d2-L1100-09 980-71-2 10 mM 435.31 d3-L1100-09 111025-46-8 10 mM 356.44

d4-L1100-09 150683-30-0 10 mM 448.94 d5-L1100-09 21187-98-4 10 mM 323.41

d6-L1100-09 53164-05-9 10 mM 415.82 d7-L1100-09 4991-65-5 10 mM 168.17

d8-L1100-09 53-43-0 10 mM 288.43 d9-L1100-09 84371-65-3 10 mM 429.59

d10-L1100-09 50264-69-2 10 mM 321.16 d11-L1100-09 434-03-7 10 mM 312.45

e1-L1100-09 300-08-3 10 mM 236.11

e2-L1100-09 108341-18-0 10 mM 337.28

e3-L1100-09 1035555-63-5 10 mM 504.23 e4-L1100-09 1062368-24-4 10 mM 406.48

e5-L1100-09 801312-28-7 10 mM 518.58 e6-L1100-09 602306-29-6 10 mM 371.46

e7-L1100-09 1092788-83-4 10 mM 319.36 e8-L1100-09 936890-98-1 10 mM 406.44

e9-L1100-09 901119-35-5 10 mM 580.46 e10-L1100-09 911222-45-2 10 mM 436.30

e11-L1100-09 1310693-92-5 10 mM 371.86 f1-L1100-09 1197160-78-3 10 mM 615.73

f2-L1100-09 501925-31-1 10 mM 311.72 f3-L1100-09 405911-17-3 10 mM 618.51

f4-L1100-09 546141-08-6 10 mM 338.40 f5-L1100-09 357263-13-9 10 mM 406.43

f6-L1100-09 1020172-07-9 10 mM 553.59 f7-L1100-09 885499-61-6 10 mM 341.84

f8-L1100-09 1166227-08-2 10 mM 393.53 f9-L1100-09 1374598-80-7 10 mM 533.63

f10-L1100-09 503468-95-9 10 mM 413.49 f11-L1100-09 908112-43-6 10 mM 464.48

g1-L1100-09 908115-27-5 10 mM 521.53 g2-L1100-09 1086062-66-9 10 mM 505.50

g3-L1100-09 207679-81-0 10 mM 341.49 g4-L1100-09 471905-41-6 10 mM 442.90

g5-L1100-09 1144068-46-1 10 mM 519.60 g6-L1100-09 146714-97-8 10 mM 531.95

g7-L1100-09 30299-08-2 10 mM 468.58 g8-L1100-09 52214-84-3 10 mM 289.15

g9-L1100-09 1196109-52-0 10 mM 456.46 g10-L1100-09 1051375-16-6 10 mM 419.38

g11-L1100-09 1062161-90-3 10 mM 528.61 h1-L1100-09 192927-92-7 10 mM 430.94

h2-L1100-09 552325-73-2 10 mM 358.44 h3-L1100-09 900515-16-4 10 mM 305.28

h4-L1100-09 939791-38-5 10 mM 665.66 h5-L1100-09 871700-17-3 10 mM 615.39

h6-L1100-09 959122-11-3 10 mM 428.48 h7-L1100-09 193611-72-2 10 mM 479.87

h8-L1100-09 58131-57-0 10 mM 279.25 h9-L1100-09 131740-09-5 10 mM 438.30

h10-L1100-09 936563-96-1 10 mM 440.50 h11-L1100-09 648449-76-7 10 mM 285.22

a1-L1100-10 1218777-13-9 10 mM 289.28 a2-L1100-10 405168-58-3 10 mM 419.91

a3-L1100-10 1138549-36-6 10 mM 513.61 a4-L1100-10 819812-04-9 10 mM 574.66

a5-L1100-10 1092499-93-8 (free base) 10 mM 563.47 a6-L1100-10 741713-40-6 10 mM 441.45

a7-L1100-10 1062159-35-6 10 mM 494.59

a8-L1100-10 851881-60-2 10 mM 369.36

a9-L1100-10 21102-95-4 10 mM 458.42 a10-L1100-10 936091-14-4 10 mM 509.67

a11-L1100-10 629664-81-9 10 mM 438.47 b1-L1100-10 1032754-93-0 10 mM 498.60

b2-L1100-10 844499-71-4 10 mM 360.39 b3-L1100-10 199864-87-3 10 mM 281.33

b4-L1100-10 1007207-67-1 10 mM 377.42 b5-L1100-10 897016-82-9 10 mM 431.53

b6-L1100-10 1116235-97-2 10 mM 532.57 b7-L1100-10 700874-71-1 10 mM 441.52

b8-L1100-10 209984-56-5 10 mM 463.48 b9-L1100-10 30562-34-6 10 mM 560.64

b10-L1100-10 209984-57-6 10 mM 479.48 b11-L1100-10 186392-40-5 10 mM 399.87

c1-L1100-10 934541-31-8 10 mM 504.64 c2-L1100-10 945595-80-2 10 mM 503.58

c3-L1100-10 208260-29-1 10 mM 389.45 c4-L1100-10 75530-68-6 10 mM 385.37

c5-L1100-10 244218-51-7 10 mM 447.96 c6-L1100-10 942487-16-3 10 mM 474.48

c7-L1100-10 586379-66-0 10 mM 477.30 c8-L1100-10 1110813-31-4 10 mM 469.94

c9-L1100-10 153436-53-4 10 mM 315.75 c10-L1100-10 264218-23-7 10 mM 359.72

c11-L1100-10 670220-88-9 10 mM 443.54 d1-L1100-10 1124329-14-1 10 mM 452.55

d2-L1100-10 936091-26-8 10 mM 524.68 d3-L1100-10 315183-21-2 10 mM 392.49

d4-L1100-10 1173204-81-3 10 mM 570.65 d5-L1100-10 942918-07-2 10 mM 507.63

d6-L1100-10 845714-00-3 10 mM 213.24 d7-L1100-10 1013101-36-4 10 mM 425.48

d8-L1100-10 1095382-05-0 10 mM 551.48 d9-L1100-10 252935-94-7 10 mM 486.31

d10-L1100-10 878739-06-1 10 mM 451.52 d11-L1100-10 913376-83-7 10 mM 539.58

e1-L1100-10 875446-37-0 10 mM 637.51 e2-L1100-10 1245537-68-1 10 mM 650.60

e3-L1100-10 452342-67-5 10 mM 425.48 e4-L1100-10 802539-81-7 10 mM 460.57

e5-L1100-10 937265-83-3 10 mM 569.63 e6-L1100-10 1071992-99-8 10 mM 561.71

e7-L1100-10 845272-21-1 10 mM 466.94 e8-L1100-10 19545-26-7 10 mM 428.43

e9-L1100-10 1339928-25-4 10 mM 508.55 e10-L1100-10 842133-18-0 10 mM 444.52

e11-L1100-10 1185763-69-2 10 mM 340.38 f1-L1100-10 1256580-46-7 10 mM 482.62

f2-L1100-10 869901-69-9 10 mM 461.87

f3-L1100-10 5142-23-4 10 mM 149.15

f4-L1100-10 779353-01-4 10 mM 396.49 f5-L1100-10 852433-84-2 10 mM 572.59

f6-L1100-10 1010085-13-8 10 mM 461.94 f7-L1100-10 211513-37-0 10 mM 389.59

f8-L1100-10 501951-42-4 10 mM 429.23 f9-L1100-10 917879-39-1 10 mM 495.55

f10-L1100-10 31430-18-9 10 mM 301.32 f11-L1100-10 95809-78-2 10 mM 388.59

g1-L1100-10 1373615-35-0 10 mM 436.96 g2-L1100-10 666260-75-9 10 mM 449.25

g3-L1100-10 251456-60-7 10 mM 307.39 g4-L1100-10 213261-59-7 10 mM 292.37

g5-L1100-10 278779-30-9 10 mM 542.84 g6-L1100-10 1009298-59-2 10 mM 462.54

g7-L1100-10 871026-44-7 10 mM 547.96 g8-L1100-10 944261-79-4 10 mM 357.79

g9-L1100-10 1029712-80-8 10 mM 412.42 g10-L1100-10 477600-75-2 10 mM 312.37

g11-L1100-10 155270-99-8 10 mM 384.43 h1-L1100-10 425637-18-9 10 mM 438.48

h2-L1100-10 262352-17-0 10 mM 600.47 h3-L1100-10 433967-28-3 10 mM 305.32

h4-L1100-10 857064-38-1 10 mM 356.22 h5-L1100-10 193275-84-2 10 mM 638.82

h6-L1100-10 658084-64-1 10 mM 391.51 h7-L1100-10 1035270-39-3 10 mM 463.57

h8-L1100-10 1032568-63-0 10 mM 480.52 h9-L1100-10 851983-85-2 10 mM 388.55

h10-L1100-10 410536-97-9 10 mM 394.47 h11-L1100-10 396129-53-6 10 mM 272.30

a1-L1100-11 1257704-57-6 10 mM 462.57 a2-L1100-11 1195765-45-7 10 mM 519.56

a3-L1100-11 1001264-89-6 10 mM 458.00 a4-L1100-11 96206-92-7 10 mM 193.24

a5-L1100-11 1224844-38-5 10 mM 309.33 a6-L1100-11 90141-22-3 10 mM 578.61

a7-L1100-11 184025-19-2 10 mM 386.40 a8-L1100-11 1217486-61-7 10 mM 441.47

a9-L1100-11 148741-30-4 10 mM 316.46 a10-L1100-11 1223001-51-1 10 mM 432.40

a11-L1100-11 112522-64-2 10 mM 269.30 b1-L1100-11 183232-66-8 10 mM 555.24

b2-L1100-11 761437-28-9 10 mM 468.94 b3-L1100-11 48208-26-0 10 mM 334.33

b4-L1100-11 865854-05-3 10 mM 334.39 b5-L1100-11 507475-17-4 10 mM 279.29

b6-L1100-11 1222781-70-5 10 mM 313.82 b7-L1100-11 183321-86-0 10 mM 379.41

b8-L1100-11 1222998-36-8 10 mM 607.62

b9-L1100-11 681136-29-8 10 mM 365.45

b10-L1100-11 481-29-8 10 mM 290.44 b11-L1100-11 956104-40-8 10 mM 477.43

c1-L1100-11 10 mM 358.39 c2-L1100-11 501437-28-1 10 mM 391.42

c3-L1100-11 194413-58-6 10 mM 238.28 c4-L1100-11 225120-65-0 10 mM 401.89

c5-L1100-11 261901-57-9 10 mM 388.95 c6-L1100-11 1187594-09-7 10 mM 371.42

c7-L1100-11 57477-39-1 10 mM 230.31 c8-L1100-11 868540-17-4 10 mM 719.91

c9-L1100-11 2854-32-2 10 mM 426.89 c10-L1100-11 711019-86-2 10 mM 472.67

c11-L1100-11 209481-20-9 10 mM 451.99 d1-L1100-11 77086-21-6 10 mM 221.30

d2-L1100-11 1227633-49-9 10 mM 429.54 d3-L1100-11 928037-13-2 10 mM 633.69

d4-L1100-11 162831-31-4 10 mM 412.25 d5-L1100-11 871362-31-1 10 mM 391.77

d6-L1100-11 61350-00-3 10 mM 232.67 d7-L1100-11 799264-47-4 10 mM 287.34

d8-L1100-11 978-62-1 10 mM 383.67 d9-L1100-11 155584-74-0 10 mM 262.74

d10-L1100-11 178606-66-1 10 mM 309.32 d11-L1100-11 211555-04-3 10 mM 376.20

e1-L1100-11 850649-61-5 10 mM 339.39 e2-L1100-11 925705-73-3 10 mM 254.25

e3-L1100-11 313516-66-4 10 mM 277.66 e4-L1100-11 220904-83-6 10 mM 520.94

e5-L1100-11 59721-29-8 10 mM 494.52 e6-L1100-11 179474-81-8 10 mM 367.87

e7-L1100-11 121917-57-5 10 mM 337.37 e8-L1100-11 51298-62-5 10 mM 269.69

e9-L1100-11 873225-46-8 10 mM 483.63 e10-L1100-11 251992-66-2 10 mM 300.40

e11-L1100-11 717907-75-0 10 mM 507.49 f1-L1100-11 504433-23-2 10 mM 275.30

f2-L1100-11 1161205-04-4 10 mM 262.69 f3-L1100-11 607742-69-8 10 mM 353.44

f4-L1100-11 10537-47-0 10 mM 282.38 f5-L1100-11 193000-39-4 10 mM 411.86

f6-L1100-11 690206-97-4 10 mM 333.74 f7-L1100-11 778270-11-4 10 mM 374.32

f8-L1100-11 1004316-88-4 10 mM 776.02 f9-L1100-11 883050-24-6 10 mM 316.35

f10-L1100-11 941685-37-6 10 mM 306.37 f11-L1100-11 220991-20-8 10 mM 293.72

g1-L1100-11 952021-60-2 10 mM 419.48 g2-L1100-11 459168-41-3 10 mM 277.75

g3-L1100-11 355025-13-7 10 mM 488.98

g4-L1100-11 53179-13-8 10 mM 185.22

g5-L1100-11 133053-19-7 10 mM 442.51 g6-L1100-11 55778-02-4 10 mM 290.36

g7-L1100-11 19542-67-7 10 mM 207.25 g8-L1100-11 244767-67-7 10 mM 329.40

g9-L1100-11 22978-25-2 10 mM 276.68 g10-L1100-11 349085-38-7 10 mM 355.39

g11-L1100-11 931398-72-0 10 mM 352.34 h1-L1100-11 137975-06-5 10 mM 427.54

h2-L1100-11 1390637-82-7 10 mM 456.59 h3-L1100-11 610798-31-7 10 mM 391.42

h4-L1100-11 405060-95-9 10 mM 479.81 h5-L1100-11 252917-06-9 (free base) 10 mM 501.80

h6-L1100-11 1186486-62-3 10 mM 638.65 h7-L1100-11 327036-89-5 10 mM 222.26

h8-L1100-11 79183-19-0 10 mM 306.14 h9-L1100-11 303162-79-0 10 mM 399.51

h10-L1100-11 63208-82-2 10 mM 367.30 h11-L1100-11 366789-02-8 10 mM 435.88

a1-L1100-12 78246-49-8 10 mM 365.83 a2-L1100-12 74711-43-6 10 mM 298.36

a3-L1100-12 444731-52-6 10 mM 437.52 a4-L1100-12 155148-31-5 10 mM 794.47

a5-L1100-12 50-78-2 10 mM 180.16 a6-L1100-12 4394-00-7 10 mM 282.22

a7-L1100-12 41621-49-2 10 mM 268.35 a8-L1100-12 168273-06-1 10 mM 463.79

a9-L1100-12 2438-72-4 10 mM 223.27 a10-L1100-12 84057-84-1 10 mM 256.09

a11-L1100-12 329-98-6 10 mM 174.19 b1-L1100-12 10083-24-6 10 mM 244.24

b2-L1100-12 50-65-7 10 mM 327.12 b3-L1100-12 668270-12-0 10 mM 472.54

b4-L1100-12 130641-38-2 10 mM 324.37 b5-L1100-12 274901-16-5 10 mM 303.40

b6-L1100-12 210421-74-2 10 mM 476.89 b7-L1100-12 23541-50-6 10 mM 563.98

b8-L1100-12 81131-70-6 10 mM 446.51 b9-L1100-12 190786-44-8 10 mM 547.06

b10-L1100-12 265121-04-8 10 mM 1004.83 b11-L1100-12 162011-90-7 10 mM 314.36

c1-L1100-12 367514-88-3 10 mM 529.14 c2-L1100-12 147403-03-0 10 mM 456.45

c3-L1100-12 26095-59-0 10 mM 563.57 c4-L1100-12 242478-38-2 10 mM 480.55

c5-L1100-12 135729-62-3 10 mM 332.87 c6-L1100-12 157212-55-0 10 mM 569.63

c7-L1100-12 182349-12-8 10 mM 532.03 c8-L1100-12 123524-52-7 10 mM 582.65

c9-L1100-12 58066-85-6 10 mM 407.57

c10-L1100-12 863031-21-4 10 mM 568.53

c11-L1100-12 86347-15-1 10 mM 236.74 d1-L1100-12 23828-92-4 10 mM 414.56

d2-L1100-12 39831-55-5 10 mM 781.76 d3-L1100-12 357-08-4 10 mM 363.84

d4-L1100-12 7491-74-9 10 mM 142.16 d5-L1100-12 69308-37-8 10 mM 213.66

d6-L1100-12 113775-47-6 10 mM 200.28 d7-L1100-12 269055-15-4 10 mM 435.28

d8-L1100-12 126784-99-4 10 mM 475.62 d9-L1100-12 753498-25-8 10 mM 508.56

d10-L1100-12 1508-65-2 10 mM 393.95 d11-L1100-12 101152-94-7 10 mM 246.35

e1-L1100-12 133099-07-7 10 mM 507.46 e2-L1100-12 154-69-8 10 mM 291.82

e3-L1100-12 130929-57-6 10 mM 305.29 e4-L1100-12 979-32-8 10 mM 356.50

e5-L1100-12 33342-05-1 10 mM 527.63 e6-L1100-12 297-76-7 10 mM 384.51

e7-L1100-12 132-17-2 10 mM 403.53 e8-L1100-12 188062-50-2 10 mM 335.35

e9-L1100-12 850-52-2 10 mM 310.43 e10-L1100-12 58579-51-4 10 mM 292.55

e11-L1100-12 82248-59-7 10 mM 291.82 f1-L1100-12 5579-84-0 10 mM 209.12

f2-L1100-12 138890-62-7 10 mM 383.51 f3-L1100-12 42835-25-6 10 mM 261.25

f4-L1100-12 549-18-8 10 mM 313.86 f5-L1100-12 62-13-5 10 mM 217.65

f6-L1100-12 3978-86-7 10 mM 522.55 f7-L1100-12 91374-20-8 10 mM 296.84

f8-L1100-12 98769-84-7 10 mM 409.50 f9-L1100-12 322-79-2 10 mM 248.16

f10-L1100-12 440-17-5 10 mM 480.42 f11-L1100-12 2468-21-5 10 mM 336.43

g1-L1100-12 59263-76-2 10 mM 269.81 g2-L1100-12 153439-40-8 10 mM 538.12

g3-L1100-12 71320-77-9 10 mM 268.74 g4-L1100-12 472-15-1 10 mM 456.70

g5-L1100-12 66104-23-2 10 mM 410.59 g6-L1100-12 1140909-48-3 10 mM 635.59

g7-L1100-12 654671-77-9 10 mM 523.32 g8-L1100-12 1070-11-7 10 mM 277.23

g9-L1100-12 10592-13-9 10 mM 480.90 g10-L1100-12 105956-97-6 10 mM 365.79

g11-L1100-12 50357-45-4 10 mM 413.34 h1-L1100-12 100299-08-9 10 mM 266.30

h2-L1100-12 223673-61-8 10 mM 396.51 h3-L1100-12 34381-68-5 10 mM 372.89

h4-L1100-12 99464-64-9 10 mM 447.46

h5-L1100-12 100643-71-8 10 mM 310.82

h6-L1100-12 10163-15-2 10 mM 143.95 h7-L1100-12 101-31-5 10 mM 289.37

h8-L1100-12 11018-89-6 10 mM 728.77 h9-L1100-12 109-57-9 10 mM 116.18

h10-L1100-12 330784-47-9 10 mM 483.95 h11-L1100-12 134308-13-7 10 mM 273.24

a1-L1100-13 57-66-9 10 mM 285.36 a2-L1100-13 51-05-8 10 mM 272.77

a3-L1100-13 80-49-9 10 mM 370.28 a4-L1100-13 51-56-9 10 mM 356.25

a5-L1100-13 2192-20-3 10 mM 447.83 a6-L1100-13 3717-88-2 10 mM 427.92

a7-L1100-13 2392-39-4 10 mM 516.40 a8-L1100-13 320345-99-1 10 mM 564.55

a9-L1100-13 14882-18-9 10 mM 362.09 a10-L1100-13 62-97-5 10 mM 389.51

a11-L1100-13 50-14-6 10 mM 396.65 b1-L1100-13 7081-53-0 10 mM 432.98

b2-L1100-13 61-12-1 10 mM 379.92 b3-L1100-13 554-57-4 10 mM 236.27

b4-L1100-13 522-48-5 10 mM 236.74 b5-L1100-13 181695-72-7 10 mM 314.36

b6-L1100-13 42924-53-8 10 mM 228.29 b7-L1100-13 79559-97-0 10 mM 342.69

b8-L1100-13 52-01-7 10 mM 416.57 b9-L1100-13 98717-15-8 10 mM 310.86

b10-L1100-13 1264-62-6 10 mM 862.05 b11-L1100-13 67-97-0 10 mM 384.64

c1-L1100-13 219861-08-2 10 mM 414.43 c2-L1100-13 23256-50-0 10 mM 291.13

c3-L1100-13 522-51-0 10 mM 527.57 c4-L1100-13 55-97-0 10 mM 362.19

c5-L1100-13 541-22-0 10 mM 418.29 c6-L1100-13 6018-19-5 10 mM 211.15

c7-L1100-13 7632-00-0 10 mM 69.00 c8-L1100-13 13463-41-7 10 mM 317.70

c9-L1100-13 318-98-9 10 mM 295.80 c10-L1100-13 61-68-7 10 mM 241.29

c11-L1100-13 274693-27-5 10 mM 522.57 d1-L1100-13 396-01-0 10 mM 253.26

d2-L1100-13 127-56-0 10 mM 236.22 d3-L1100-13 846589-98-8 10 mM 232.15

d4-L1100-13 50-50-0 10 mM 376.49 d5-L1100-13 386750-22-7 10 mM 381.46

d6-L1100-13 93413-62-8 10 mM 263.38 d7-L1100-13 56-92-8 10 mM 184.07

d8-L1100-13 149676-40-4 10 mM 465.49 d9-L1100-13 26921-17-5 10 mM 432.49

d10-L1100-13 1716-12-7 10 mM 186.18

d11-L1100-13 23031-32-5 10 mM 548.65

e1-L1100-13 53936-56-4 10 mM 194.23 e2-L1100-13 540737-29-9 10 mM 504.49

e3-L1100-13 162359-56-0 10 mM 343.90 e4-L1100-13 635318-55-7 10 mM 235.22

e5-L1100-13 775304-57-9 10 mM 284.24 e6-L1100-13 745833-23-2 10 mM 404.30

e7-L1100-13 172889-27-9 10 mM 301.77 e8-L1100-13 19983-44-9 10 mM 211.19

e9-L1100-13 550-24-3 10 mM 294.39 e10-L1100-13 1201438-56-3 10 mM 416.86

e11-L1100-13 1174043-16-3 10 mM 395.43 f1-L1100-13 194423-15-9 10 mM 369.22

f2-L1100-13 20350-15-6 10 mM 280.36 f3-L1100-13 935888-69-0 10 mM 532.61

f4-L1100-13 1152311-62-0 10 mM 520.50 f5-L1100-13 1373423-53-0(free base) 10 mM 453.96

f6-L1100-13 485-49-4 10 mM 367.35 f7-L1100-13 6384-92-5 10 mM 147.13

f8-L1100-13 188968-51-6 10 mM 588.66 f9-L1100-13 1118807-13-8 10 mM 376.86

f10-L1100-13 856925-71-8 10 mM 292.33 f11-L1100-13 3690-10-6 10 mM 228.20

g1-L1100-13 659730-32-2 10 mM 430.40 g2-L1100-13 380315-80-0 10 mM 369.48

g3-L1100-13 1316214-52-4 10 mM 433.50 g4-L1100-13 1372540-25-4 10 mM 433.42

g5-L1100-13 196868-63-0 10 mM 341.79 g6-L1100-13 1021868-92-7 10 mM 367.91

g7-L1100-13 438190-29-5 10 mM 273.23 g8-L1100-13 1392399-03-9 10 mM 600.02

g9-L1100-13 1232410-49-9 10 mM 368.41 g10-L1100-13 118409-57-7 10 mM 186.17

g11-L1100-13 866206-55-5 10 mM 517.96 h1-L1100-13 686347-12-6 10 mM 546.88

h2-L1100-13 885101-89-3 10 mM 347.41 h3-L1100-13 1188910-76-0 10 mM 517.46

h4-L1100-13 1260141-27-2 10 mM 461.46 h5-L1100-13 1143532-39-1 10 mM 428.92

h6-L1100-13 317318-84-6 10 mM 471.49 h7-L1100-13 960203-27-4 10 mM 379.36

h8-L1100-13 864070-44-0 10 mM 450.91 h9-L1100-13 301305-73-7 10 mM 360.43

h10-L1100-13 146535-11-7 10 mM 266.29 h11-L1100-13 188591-46-0 10 mM 392.78

a1-L1100-14 206873-63-4 10 mM 646.73 a2-L1100-14 50892-23-4 10 mM 323.80

a3-L1100-14 110078-46-1 10 mM 502.78 a4-L1100-14 1177865-17-6 10 mM 530.96

a5-L1100-14 1370261-97-4,1370261-96-3(fr10 mM 429.91

a6-L1100-14 608141-41-9 10 mM 460.50

a7-L1100-14 1246086-78-1 10 mM 422.29 a8-L1100-14 487-52-5 10 mM 272.25

a9-L1100-14 4311-88-0 10 mM 259.33 a10-L1100-14 1048371-03-4 10 mM 279.29

b1-L1100-14 1207360-89-1 10 mM 452.55 b2-L1100-14 870483-87-7 10 mM 366.41

b3-L1100-14 287383-59-9 10 mM 326.35 b4-L1100-14 1257044-40-8 10 mM 868.44

b5-L1100-14 441798-33-0 10 mM 588.27

Catalog Number TargetS1001 Bcl-2S1002 Autophagy

S1003 CSF-1RS1004 PARP

S1005 c-KitS1006 Bcr-Abl

S1007 HIFS1008 MEK

S1009 ATM/ATRS1010 FGFR

S1011 EGFRS1013 Proteasome

S1014 SrcS1017 VEGFR

S1018 c-KitS1019 EGFR

S1020 MEKS1021 Bcr-Abl

S1022 mTORS1023 Autophagy

S1025 EGFRS1026 Bcr-Abl

S1028 EGFRS1029 TNF-alpha

S1032 c-KitS1033 Bcr-Abl

S1034 IGF-1RS1035 c-Kit

S1036 MEKS1038 Autophagy

S1039 AutophagyS1040 PDGFR

S1041S1042 c-Kit

S1043 FLT3S1044 mTOR

S1045 HDACS1046 VEGFR

S1047 AutophagyS1048 Aurora Kinase

S1049 AutophagyS1052 HSP (e.g. HSP90)

S1053 HDACS1055 PKC

S1056 EGFRS1057 Autophagy

S1060 PARPS1061 E3 Ligase

S1064 c-Kit

S1065 PI3K

S1066 MEKS1067 TGF-beta/Smad

S1068 ALKS1069 HSP (e.g. HSP90)

S1070 c-MetS1071 Bcl-2

S1072 PI3KS1075 GSK-3

S1076 p38 MAPKS1077 p38 MAPK

S1078 AktS1079 EGFR

S1080 c-MetS1082 Hedgehog

S1084 FGFRS1085 HDAC

S1087 PARPS1088 IGF-1R

S1090 HDACS1091 IGF-1R

S1092 ATM/ATRS1093 IGF-1R

S1094 c-MetS1095 HDAC

S1096 HDACS1097

S1098 PARPS1100 Aurora Kinase

S1101 c-KitS1102 MEK

S1103 Aurora KinaseS1104 Raf

S1105 AutophagyS1106 PDK-1

S1107 Aurora KinaseS1108 ALK

S1109 PLKS1110 Phospholipase (e.g. PLA)

S1111 c-MetS1112 c-Met

S1113 AktS1114 c-Met

S1115 Cathepsin KS1116 CDK

S1117 AktS1118 PI3K

S1119 AxlS1120 mTOR

S1121 Bcl-2

S1122 HDAC

S1123 P450 (e.g. CYP17)S1129 Sirtuin

S1130 E3 Ligase S1132 PARP

S1133 Aurora KinaseS1134 Aurora Kinase

S1135 DHFRS1138 FGFR

S1139 Opioid ReceptorS1140 Androgen Receptor

S1141 HSP (e.g. HSP90)S1142 HSP (e.g. HSP90)

S1143 EGFRS1144 CFTR

S1145 CDKS1146 Hedgehog

S1147 Aurora KinaseS1148 Microtubule Associated

S1149 AutophagyS1150 Autophagy

S1152 RafS1153 CDK

S1154 Aurora KinaseS1155 STAT

S1156 DNA/RNA SynthesisS1158 Dehydrogenase

S1159 HSP (e.g. HSP90)S1160 Potassium Channel

S1163 HSP (e.g. HSP90)S1164 VEGFR

S1165 Microtubule AssociatedS1166 DNA/RNA Synthesis


S1169 PI3KS1170 EGFR

S1171 Aurora KinaseS1172 E3 Ligase

S1173 EGFRS1174 Androgen Receptor

S1175 HSP (e.g. HSP90)S1177 MEK

S1178 c-KitS1179 EGFR

S1180 Wnt/beta-cateninS1181 Aurora Kinase

S1183 HCV ProteaseS1185 HIV Protease

S1186 Telomerase

S1187 PI3K

S1188 AromataseS1189 Substance P

S1190 Androgen ReceptorS1191 Estrogen/progestogen Recepto

S1192 DNA/RNA SynthesisS1193 E3 Ligase

S1194 EGFRS1195 P450 (e.g. CYP17)

S1196 AromataseS1197 5-alpha Reductase

S1198 TopoisomeraseS1199 DNA/RNA Synthesis

S1200 DNA MethyltransferaseS1201

S1202 5-alpha ReductaseS1205 DNA-PK

S1206 Adrenergic ReceptorS1207 c-Kit

S1208 AutophagyS1209 DNA/RNA Synthesis

S1210 DHFRS1212

S1213 DNA/RNA SynthesisS1214 DNA/RNA Synthesis

S1215 DNA/RNA SynthesisS1216 Epigenetic Reader Domain


S1219 PI3KS1220 c-Kit

S1221 DNA/RNA SynthesisS1223 Topoisomerase

S1224 DNA/RNA SynthesisS1225 Topoisomerase

S1226 mTORS1227 Estrogen/progestogen Recepto


S1231 TopoisomeraseS1233 HIF

S1234 IGF-1RS1235 Aromatase

S1237 AutophagyS1241 Autophagy

S1243 5-HT ReceptorS1244 c-Kit

S1248 AChRS1249 Aurora Kinase

S1250 Androgen Receptor

S1251 Estrogen/progestogen Recepto

S1256 Sodium ChannelS1257

S1258 P2 ReceptorS1259 MT Receptor

S1260 CaSRS1261 COX

S1262 Beta AmyloidS1264 FGFR

S1266 mTORS1267 Raf

S1268 PI3KS1274 IκB/IKK

S1275 PDK-1S1280 Dopamine Receptor

S1281 AMPA Receptor-kainate RecepS1283 5-HT Receptor

S1284 RAASS1285 AChR


S1290S1291 Histamine Receptor

S1293 Calcium ChannelS1294 PDE

S1297 Microtubule AssociatedS1299 DNA/RNA Synthesis


S1304 Androgen ReceptorS1305 DNA/RNA Synthesis

S1314 PKCS1315 LPA Receptor

S1316 c-MetS1319 Telomerase

S1322 AutophagyS1324 Adrenergic Receptor

S1327 TopoisomeraseS1328 COX

S1329 GABA ReceptorS1332 GABA Receptor

S1333 5-HT ReceptorS1334 DNA/RNA Synthesis

S1336 5-HT ReceptorS1338 GABA Receptor

S1339 AChRS1342 Topoisomerase

S1344 DPP-4S1345 5-HT Receptor

S1352 PI3K

S1353 P450 (e.g. CYP17)

S1354 Proton PumpS1357 Histamine Receptor

S1358 Histamine ReceptorS1359 RAAS

S1360 mTORS1361 c-Met

S1362 PLKS1363 c-Kit

S1364 Microtubule AssociatedS1366 Integrase

S1367 TopoisomeraseS1375 Carbonic Anhydrase

S1376 Estrogen/progestogen ReceptoS1377 Estrogen/progestogen Recepto

S1378 JAKS1379 Hydroxylase

S1380 HIV ProteaseS1382 Histamine Receptor

S1383 Lysyl HydroxylaseS1384 DNA/RNA Synthesis

S1385 5-HT ReceptorS1386 Proteasome

S1387 Adrenergic ReceptorS1389 Autophagy

S1390 5-HT ReceptorS1391 Sodium Channel


S1397 AChRS1398 Reverse Transcriptase

S1400 Reverse TranscriptaseS1401 Reverse Transcriptase

S1404 DehydrogenaseS1409 Adrenergic Receptor

S1410 PI3KS1415 P2 Receptor

S1421 PKCS1422 HDAC

S1425 Calcium ChannelS1426 Potassium Channel

S1430 PDES1431 PDE

S1432 5-HT ReceptorS1436 5-HT Receptor

S1437 Adrenergic ReceptorS1438 Carbonic Anhydrase

S1440 AChRS1441 5-HT Receptor

S1442 P450 (e.g. CYP17)

S1443

S1451 Aurora KinaseS1452 Kinesin

S1453 TransferaseS1454 Aurora Kinase

S1455 PDES1456 Endothelin Receptor

S1457 HIV ProteaseS1459 ROCK

S1460 JNKS1463 Topoisomerase

S1465 TopoisomeraseS1468

S1470 FGFRS1472 MAO

S1474 ROCKS1475 MEK

S1476 TGF-beta/SmadS1478 ATPase

S1480 HCV ProteaseS1481 P-gp

S1482 HCV ProteaseS1484 HDAC

S1485 PLKS1486 EGFR

S1487 CDKS1488 5-HT Receptor

S1489 PI3KS1490 Bcr-Abl

S1491 DNA/RNA SynthesisS1494 p38 MAPK

S1497 DHFRS1498 HSP (e.g. HSP90)

S1501 DehydrogenaseS1504 PDE

S1506 RAASS1507 RAAS

S1512 PDES1515 HDAC

S1518 COXS1519 Aurora Kinase

S1522 AminopeptidaseS1523 mTOR

S1524 CDKS1525 Wee1

S1526 FLT3S1528 Beta Amyloid

S1529 Aurora KinaseS1530 MEK

S1531 MEK

S1532 Chk

S1533 SykS1536 PDGFR

S1537 VDAS1538 HCV Protease

S1540 DPP-4S1541 Sirtuin

S1544 Cannabinoid ReceptorS1545 OX Receptor

S1548 SGLTS1549 Adrenergic Receptor

S1550 PDES1555 mTOR

S1556 AktS1557 PDGFR

S1558 AktS1561 Axl

S1565 CFTRS1567 TNF-alpha

S1568 MEKS1570 ATM/ATR

S1572 CDKS1573 Autophagy

S1574 p38 MAPKS1577 Tie-2

S1578 RAASS1579 CDK

S1582 PKAS1590 GSK-3

S1591S1593 Factor Xa

S1594 Gamma-secretaseS1604 RAAS

S1607 5-HT ReceptorS1608 AChR

S1611S1613 Adrenergic Receptor

S1614 Sodium ChannelS1615 5-HT Receptor

S1623 AChRS1624

S1626 COXS1627

S1629S1630 OX Receptor

S1631S1633

S1638 COXS1639 HIV Protease

S1642

S1645 COX

S1646 COXS1648 DNA/RNA Synthesis

S1649 5-HT ReceptorS1657 RAAS

S1662 Calcium ChannelS1665 Estrogen/progestogen Recepto

S1666S1672 Aromatase

S1673 PDES1693 Autophagy

S1698S1702 Reverse Transcriptase

S1703 AutophagyS1704 Reverse Transcriptase

S1706 Reverse TranscriptaseS1707

S1713 COXS1714 Autophagy

S1718 Reverse TranscriptaseS1719 Reverse Transcriptase

S1724 Dopamine ReceptorS1738 RAAS

S1742 Reverse TranscriptaseS1743 Proton Pump

S1747 AutophagyS1748

S1754 AChRS1763 Dopamine Receptor

S1771 Dopamine ReceptorS1774 DNA Methyltransferase

S1776 Estrogen/progestogen ReceptoS1782 DNA Methyltransferase

S1791S1792

S1793 RAASS1801 Histamine Receptor

S1802 AMPKS1805 AChR

S1808S1813 Calcium Channel

S1816 Histamine ReceptorS1827 Adrenergic Receptor


S1831 Adrenergic ReceptorS1833


S1840

S1845 Histamine Receptor

S1847 Histamine ReceptorS1854


S1869 5-HT ReceptorS1875

S1880 Histamine ReceptorS1885 Calcium Channel


S1894 RAASS1898 5-HT Receptor

S1903 COXS1905 Calcium Channel

S1908 P450 (e.g. CYP17)S1909 HMG-CoA Reductase

S1913 AChRS1914 Estrogen/progestogen Recepto

S1915S1929 AChR

S1941 Opioid ReceptorS1950 Autophagy

S1959 COXS1960

S1969 GABA ReceptorS1971 Potassium Channel


S1975 5-HT ReceptorS1978 AChR

S1979 AutophagyS1981 DNA/RNA Synthesis


S1984 P2 ReceptorS1994 Calcium Channel

S1995 DNA/RNA SynthesisS1996 5-HT Receptor

S2000 ATPaseS2001 Integrase

S2003 CCR5S2005 Integrase

S2006 DHFRS2011 Dopamine Receptor

S2012 HDACS2013 FAK

S2014 CDKS2015

S2018 Aurora Kinase

S2020 Adrenergic Receptor

S2024 Histamine ReceptorS2025 5-HT Receptor

S2026 GABA ReceptorS2029 DNA/RNA Synthesis

S2030 Calcium ChannelS2032

S2035S2037 RAAS

S2038 Adrenergic ReceptorS2040 COX

S2042 Androgen ReceptorS2043 AMPA Receptor-kainate Recep


S2046 P450 (e.g. CYP17)S2047 COX

S2050 Calcium ChannelS2051 RAAS

S2054 AChRS2055 Dehydrogenase

S2059 Adrenergic ReceptorS2061 HMG-CoA Reductase


S2067S2073 Potassium Channel

S2075 PPARS2076 RAAS

S2077 HMG-CoA ReductaseS2078 Histamine Receptor

S2079 RAASS2080 Calcium Channel

S2081 RAASS2082

S2084 5-HT ReceptorS2085 Opioid Receptor

S2086 Adrenergic ReceptorS2087 AChR

S2090 Adrenergic ReceptorS2091 Adrenergic Receptor

S2092 Adrenergic ReceptorS2095 RAAS

S2096 5-HT ReceptorS2097

S2098S2099 RAAS

S2101 ProteasomeS2102 MAO

S2103 Opioid Receptor

S2104 Dopamine Receptor

S2106 5-HT ReceptorS2107 Histamine Receptor

S2108 COXS2110 Sodium Channel

S2111 EGFRS2112 5-HT Receptor

S2113 Adrenergic ReceptorS2118 Sodium Channel

S2126 Adrenergic ReceptorS2127 PDE

S2128 Estrogen/progestogen ReceptoS2130 AChR

S2131 PDES2133 GABA Receptor

S2134 MEKS2149 GPR

S2150 EGFRS2151 Smoothened

S2153 5-alpha ReductaseS2154

S2155S2156

S2157 HedgehogS2158 Aurora Kinase

S2159S2163 S6 Kinase


S2170 HDACS2178 PARP

S2179 JAKS2180 Proteasome

S2181 ProteasomeS2182 Kinesin

S2183 FGFRS2185 EGFR

S2186 TGF-beta/SmadS2187 P450 (e.g. CYP17)

S2192 EGFRS2193 PLK

S2194 FLT3S2198 Pim

S2199 RAASS2201 c-Met

S2202 Bcr-AblS2205 EGFR

S2206 SykS2207 PI3K

S2208 Aromatase

S2209 Microtubule Associated

S2214 JAKS2215 Beta Amyloid

S2216 HER2S2217 Topoisomerase

S2218 AutophagyS2219 JAK

S2220 RafS2221 VEGFR

S2225 APCS2226 PI3K

S2227 PI3KS2229

S2230 TGF-beta/SmadS2231 c-Kit

S2232 5-HT ReceptorS2233 ATPase

S2235 PLKS2238 mTOR

S2240 AChRS2243 Bcr-Abl

S2244 HDACS2245 ATM/ATR

S2246 P450 (e.g. CYP17)S2247 PI3K

S2248 PKCS2251 GluR

S2256S2259

S2262 P450 (e.g. CYP17)S2263

S2265S2266 p38 MAPK

S2268 P450 (e.g. CYP17)S2269

S2285 STATS2287

S2308 Histamine ReceptorS2310 Akt

S2312 PDES2320 PDE

S2322 Opioid ReceptorS2332

S2341 E3 Ligase S2346

S2352S2362 Androgen Receptor

S2374S2375

S2379

S2386 GSK-3

S2391 PI3KS2394 P450 (e.g. CYP17)

S2396S2401 P450 (e.g. CYP17)

S2403 Calcium ChannelS2406 EGFR

S2415 TGF-beta/SmadS2417

S2423 TopoisomeraseS2425

S2437 Calcium ChannelS2438 Adrenergic Receptor

S2443 Potassium ChannelS2449 cAMP

S2450 Estrogen/progestogen ReceptoS2451 Dopamine Receptor

S2452 Dopamine ReceptorS2453 Dopamine Receptor

S2454 cAMPS2455 AChR

S2456 Dopamine ReceptorS2458 Adrenergic Receptor

S2459 5-HT ReceptorS2460 Dopamine Receptor

S2461 Dopamine ReceptorS2462 AChR

S2466 Estrogen/progestogen ReceptoS2470

S2471 AChRS2473 Estrogen/progestogen Recepto

S2475 PDGFRS2480 Autophagy

S2481 Calcium ChannelS2482 Calcium Channel

S2484 ATPaseS2485

S2489 Potassium ChannelS2490 AChR

S2491 AutophagyS2493 5-HT Receptor

S2494 Histamine ReceptorS2495 Adrenergic Receptor

S2496 Factor XaS2497 AChR


S2503 Opioid ReceptorS2505 PPAR


S2508 AChR


S2512S2515 PDE




S2524 Sodium ChannelS2525 Sodium Channel

S2526 P450 (e.g. CYP17)S2529 Dopamine Receptor

S2531 COXS2533 Adrenergic Receptor

S2541 5-HT ReceptorS2542 AMPK

S2545 Adrenergic ReceptorS2547 AChR

S2548S2549 AChR

S2550 AChRS2552 Histamine Receptor

S2554 DNA/RNA SynthesisS2555 P450 (e.g. CYP17)

S2556 PPARS2560 Sodium Channel

S2561 Estrogen/progestogen ReceptoS2562

S2566 Adrenergic ReceptorS2567 Estrogen/progestogen Recepto

S2569 Adrenergic ReceptorS2573 Calcium Channel

S2577 COXS2579 Reverse Transcriptase

S2581 RAASS2582 5-HT Receptor


S2593 Vasopressin ReceptorS2601 Potassium Channel

S2602 COXS2603 Carbonic Anhydrase

S2604 Androgen ReceptorS2606 Estrogen/progestogen Recepto

S2610S2611 Estrogen/progestogen Recepto

S2614 AChR

S2615

S2617 MEKS2618 TGF-beta/Smad

S2620 PDES2621 CDK

S2622 DNA-PKS2624 mTOR

S2625 SykS2626 Chk

S2627 HDACS2628 mTOR

S2629 AChRS2630 Liver X Receptor

S2631 FAAHS2632 gp120/CD4

S2634 Bcr-AblS2635 Akt

S2636 PI3KS2637 GPR

S2638 DNA-PKS2639 HSP (e.g. HSP90)

S2656 HSP (e.g. HSP90)S2658 mTOR

S2659 AChRS2660 Beta Amyloid

S2661 mTORS2663 5-HT Receptor

S2664 RAASS2665 PPAR

S2666 FAAHS2667 Integrase

S2668 mTORS2669 5-HT Receptor

S2670 AktS2671 PI3K

S2672 FAKS2673 MEK

S2674 TransferaseS2677 5-HT Receptor

S2678 DNA/RNA SynthesisS2679 CDK

S2680 BTKS2681 PI3K

S2682 PI3KS2683 Chk

S2684 DNA/RNA SynthesisS2685 HSP (e.g. HSP90)

S2686 JAKS2688 CDK

S2689 mTOR

S2690 GluR

S2691 5-HT ReceptorS2692 c-RET

S2694 FXRS2696 mTOR

S2697 AMPKS2698 5-HT Receptor

S2699 mTORS2700 Src

S2703 ALKS2704 TGF-beta/Smad

S2711 Gamma-secretaseS2713 Autophagy

S2714 Gamma-secretaseS2717 Phosphorylase

S2718 Aurora KinaseS2719 Aurora Kinase

S2720 RafS2721 Calcium Channel

S2722 Opioid ReceptorS2725 Aurora Kinase

S2726 p38 MAPKS2727 EGFR

S2728 EGFRS2729 GSK-3

S2730 PDGFRS2731 Kinesin

S2736 JAKS2738 Caspase

S2739 PI3KS2740 Aurora Kinase

S2742 CDKS2743 Akt

S2744 Aurora KinaseS2745 GSK-3

S2746 RafS2747 c-Met

S2748 CETPS2749 mTOR

S2750 TGF-beta/SmadS2751 CDK

S2752 EGFRS2754 E3 Ligase

S2755 EGFRS2758 ATM/ATR

S2759 HDACS2760 SGLT

S2761 c-MetS2762 ALK

S2765 Integrase

S2767 Autophagy

S2768 CDKS2769 c-Kit

S2770 Aurora KinaseS2772 CETP

S2773 TRPVS2774 c-Met

S2775 AutophagyS2776 Dehydrogenase

S2777 SmoothenedS2778 Cannabinoid Receptor

S2779 HDACS2781 E3 Ligase

S2782 FXRS2783 mTOR

S2784 EGFRS2785 Sodium Channel

S2788 c-MetS2789 JAK

S2790S2791 PKC

S2792 CETPS2795 GluR

S2796 JAKS2797 Transferase

S2799S2801 FGFR

S2802 PI3KS2803 Androgen Receptor

S2804 SirtuinS2805 TGF-beta/Smad

S2806 JAKS2807 Raf

S2808 AktS2809 GluR

S2811 mTORS2812 Bcl-2

S2813 Histamine ReceptorS2814 PI3K

S2816 HER2S2817 ATM/ATR

S2818 HDACS2819 Cannabinoid Receptor

S2820 FAKS2821 DNA Methyltransferase

S2823 GSK-3S2824 IκB/IKK

S2825 Potassium ChannelS2826 EGFR

S2827 Autophagy

S2828 FAAH

S2832 Estrogen/progestogen ReceptoS2840 Adrenergic Receptor

S2842 VEGFRS2843 S6 Kinase

S2845 VEGFRS2847

S2849 5-HT ReceptorS2851 JAK

S2852 5-HT ReceptorS2853 Proteasome

S2854 Cannabinoid ReceptorS2855 P2 Receptor

S2856 5-HT ReceptorS2857 GluR

S2858S2859 c-Met

S2860 5-HT ReceptorS2861 GluR

S2862 GluRS2863 NOD1

S2864 IκB/IKKS2865 5-HT Receptor

S2866 Carbonic AnhydraseS2867 EGFR

S2868 DPP-4S2870 PI3K

S2871 PPARS2872 Raf

S2874 HCV ProteaseS2875 5-HT Receptor

S2876 GluRS2877

S2882 IκB/IKKS2885

S2890 FAKS2891 Trk receptor

S2892 GluRS2894 5-HT Receptor

S2895 EGFRS2896 VEGFR

S2897 VEGFRS2899 Bcr-Abl

S2900 P450 (e.g. CYP17)S2901

S2902 JAKS2903 COX

S2904 ChkS2905 Histamine Receptor

S2906 LPA Receptor

S2907 TGF-beta/Smad

S2911 PKCS2912 CXCR

S2913 E2 conjugatingS2914 Reverse Transcriptase

S2915 PPARS2918

S2919 HIFS2920 Vasopressin Receptor

S2921 P450 (e.g. CYP17)S2922 EGFR

S2923S2924 GSK-3

S2925 CETPS2926 GSK-3

S2927 CaspaseS2928 p38 MAPK

S2929 AutophagyS3002 Factor Xa

S3005 5-HT ReceptorS3008 COX

S3012 c-KitS3013 CXCR

S3017 ProteasomeS3018 GABA Receptor

S3019 ATPaseS3021 Cannabinoid Receptor

S3023 COXS3024 Sodium Channel

S3025S3026 Syk

S3030 AutophagyS3031 DPP-4

S3032S3033 DPP-4

S3034 Endothelin ReceptorS3035 Telomerase

S3036 HMG-CoA ReductaseS3037 Histamine Receptor

S3038S3043 COX


S3047 AChRS3048 AChR

S3050 5-HT ReceptorS3051 Endothelin Receptor

S3052 Histamine ReceptorS3053 Calcium Channel

S3056 Akt

S3057 RAAS


S3065S3066 Opioid Receptor

S3070S3072 GABA Receptor

S3075 Adrenergic ReceptorS3080 Reverse Transcriptase

S3081S3083 Adrenergic Receptor

S3117 AChRS3140

S3144 AChRS3146 Histamine Receptor

S3147 Histone MethyltransferaseS3149 Estrogen/progestogen Recepto

S3151 Potassium ChannelS3160 Estrogen/progestogen Recepto

S3163 Histamine ReceptorS3165 Reverse Transcriptase

S3167 Estrogen/progestogen ReceptoS3172 PDE


S3178 Carbonic AnhydraseS3181 Topoisomerase

S3183 5-HT ReceptorS3185 Adrenergic Receptor


S3199S3200 COX



S3212 MAOS3603 Topoisomerase

S4000 Dopamine ReceptorS4001 Axl

S4002 DPP-4S4004

S4005 MMPS4006



S4011 COX

S4012 Histamine Receptor

S4013S4014 AChR


S4019 PDES4021 Transferase

S4022S4023 Sodium Channel

S4024 AChRS4025 AChR

S4026 Histamine ReceptorS4027 AChR

S4028 IL ReceptorS4031 AChR

S4032S4034 AChR

S4035S4037

S4038 Sodium ChannelS4039 Carbonic Anhydrase


S4051 COXS4053 5-HT Receptor

S4054 Androgen ReceptorS4058

S4060S4063

S4064 5-HT ReceptorS4065 Adrenergic Receptor

S4066 PKCS4069 AChR

S4072 AChRS4073 NF-κB

S4074S4075 Proton Pump


S4079 P2 ReceptorS4080 Sodium Channel

S4081 AutophagyS4109 5-HT Receptor

S4110S4112 5-HT Receptor


S4119 TopoisomeraseS4123 Adrenergic Receptor

S4125 HDAC


S4132S5001 JAK

S5002 Bcr-AblS6001 GluR

S6003 CFTRS6005 p38 MAPK

S7008 SrcS7024 STAT

S7025 IAPS7028 PI3K

S7029 PARPS7039 EGFR

S7046 ATPaseS7049 Proteasome

S7059 CFTRS7070 Histone demethylases

S7071 GABA ReceptorS7072 GluR

S7077 IntegrinS7096 Wnt/beta-catenin

S7099 ATPaseS7113 DNA Methyltransferase

S7115 TRPVS8000 E3 Ligase

S8001 HDACS8002 PI3K

S8003 IGF-1RS8004 JAK

S8005 PimS8006 Histone Methyltransferase

S8007 ATM/ATRS8009 EGFR

S8010 5-HT ReceptorS8012 Cannabinoid Receptor

S8014 GPRS8015 CSF-1R

S8016 Potassium ChannelS8019 Akt

S8020 PPARS8021 5-HT Receptor

S8022 SGLTS8023 FLT3

S8024 c-KitS8025 PPAR

S8028 P-gpS8029 PPAR

S8030 CXCRS8031 Rac

S8032 Syk

S8034 PDE

S8035 GluRS8036 EGFR

S8037 TNF-alphaS8038 PARP

S8040 mTORS8042 CSF-1R

S8043 HDACS8048 Bcl-2

S8051 Endothelin Receptor

Brief descriptionABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively.

Linifanib (ABT-869) is a novel, potent ATP-competitive RTK inhibitor for KDR, CSF-1R, Flt-1, Flt-3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM, 3 nM, and 66 nM respectively.ABT-888 (Veliparib, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively.

Axitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively.Saracatinib (AZD0530) is a Src inhibitor for c-Src and v-Abl with IC50 of 2.7 nM and 30 nM, respectively.

FG-4592 is an HIF α prolyl hydroxylase inhibitor.AZD6244 (Selumetinib, ARRY-142886) is highly potent to inhibit MEK1 with IC50 of 14 nM.

BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM.BIBF1120 (Vargatef) is a potent inhibitor of VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.

BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.Bortezomib is a potent 20S proteasome inhibitor with Ki of 0.6 nM.

Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively.Cediranib (AZD2171) is a highly potent VEGFR2 inhibitor with IC50 of 0.5 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM.

Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.CI-1033 is a potent inhibitor of EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, respectively.

CI-1040 (PD 184352) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM.

Deforolimus (Ridaforolimus, AP23573, MK-8669) is a selective mTOR inhibitor with IC50 of 0.2 nM.Erlotinib HCl is an HER1/EGFR inhibitor with IC50 of 2 nM.

Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.

Lapatinib Ditosylate (GW572016, GW2016, Tykerb, Tyverb) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.Lenalidomide (Revlimid, CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM.

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.Nilotinib (AMN-107, Tasigna) is a Bcr-Abl inhibitor with IC50 less than 30 nM.

NVP-AEW541 is a potent inhibitor of IGF-1R with IC50 of 86 nM.Pazopanib Hydrochloride (GW786034, Votrient, Armala) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively.

PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM.PI-103 is a potent, ATP-competitive PI3K inhibitor of DNA-PK, p110α, mTORC1, PI3KC2β, p110δ, mTORC2, p110β, and p110γ with IC50 of 2 nM, 8 nM, 20 nM, 26 nM, 48 nM, 83 nM, 88 nM and 150 nM, respectively.

Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor with IC50 of ~0.1 nM.Sorafenib Tosylate (Bay 43-9006, Nexavar) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.

STF-62247 is selectively toxic and growth inhibitory to renal cells lacking VHLSunitinib Malate (Sutent, SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.

Tandutinib (MLN518, CT53518) is an ATP-competitive and highly selective inhibitor of Flt3, PDGFRβ and c-Kit with IC50 of 0.22 μM, 0.20 μM and 0.17 μM, respectively.Temsirolimus (CCI-779, Torisel) is a specific mTOR inhibitor with IC50 of 1.76 μM.

Trichostatin A (TSA) is an HDAC inhibitor with IC50 of ~1.8 nM.Vandetanib (Zactima, ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM.

Vorinostat (suberoylanilide hydroxamic acid, SAHA, Zolinza) is an HDAC inhibitor with IC50 of ~10 nM.VX-680 (MK-0457, Tozasertib) is a pan-Aurora inhibitor of Aurora A, Aurora B and Aurora C with Kiapp of 0.6 nM, 18 nM and 4.6 nM, respectively.

Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM.Elesclomol (STA-4783) is a novel potent oxidative stress inducer that illicits pro-apoptosis events among tumor cells..

MS-275 is an HDAC inhibitor of HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, respectively.Enzastaurin (LY317615) is a potent PKC inhibitor for PKCβ, PKCα, PKCγ and PKCε with IC50 of 6 nM, 39 nM, 83 nM and 110 nM, respectively.

BMS-599626 (AC480) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, respectively.Obatoclax (GX15-070) is an inhibitor of Bcl-2 with Ki of 0.22 μM.

Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1 and PARP2 with IC50 of 5 nM and 1 nM, respectively. Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM.

Masitinib is a novel tyrosine kinases inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, resectively.

Dasatinib (BMS-354825, Sprycel) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of ＜1 nM, 0.5 nM and 79 nM, respectively.

GDC-0941 is a potent inhibitor of PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ with IC50 of 3 nM, 33 nM, 3 nM and 75 nM, respectively.

SL327 is a selective inhibitor for MEK1 and MEK2 with IC50 of 0.18 μM and 0.22 μM, respectively.SB 431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM.

PF-2341066 (Crizotinib) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nnM, respectivley.NVP-AUY922 (VER-52296) is a highly potent HSP90 inhibitor for HSP90α and HSP90β with IC50 of 13 nM and 21 nM, respectively.

PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9 nM.HA14-1 is a nonpeptidic ligand of a Bcl-2 surface pocket with IC50 of~9 μM.

ZSTK474 is a potent pan-class I PI3K inhibitor with IC50 of 37 nM.SB 216763 is a potent and selective GSK-3α inhibitor with IC50 of 34.3 nM.

SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM and blocks PKB phosphorylation with IC50 of 3-5 μM. SB 202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38α and p38β with IC50 of 50 nM and 100 nM, respectively.

MK-2206 2HCl is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC50 of 8 nM, 12 nM and 65 nM, respectively.PD153035 is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM, respectively.

SU11274 is a selective Met inhibitor with IC50 of 10 nM.GDC-0449 (Vismodegib, HhAntag691) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM.

Brivanib is an ATP-competitive inhibitor against human VEGFR2 and FGFR with IC50 of 25 nM and 148 nM, respectively.Belinostat (PXD101) is a novel HDAC inhibitor with IC50 of 27 nM in HeLa cell extracts.

BSI-201 (Iniparib, SAR240550) is a PARP1 inhibitor.NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.

PCI-24781 (CRA-024781) is a novel broad spectrum HDAC inhibitor targeting HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki of 7 nM, 19 nM, 8.2 nM, 17 nM, 280 nM, 24 nM, respectively.OSI-906 (Linsitinib) is a selective inhibitor of IGF-1R and IR with IC50 of 35 nM and 75 nM, respectively.

KU-55933 is a potent and specific ATM inhibitor with IC50 and Ki of 13 nM and 2.2 nM, respectively.GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM, respectively.

PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM.LAQ824 (NVP-LAQ824) is a novel HDAC inhibitor with IC50 of 32 nM.

JNJ-26481585 (Quisinostat) is an HDAC inhibitor for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11 with IC50 of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM and 0.37 nM, respectively.BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.

Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM.MLN8054 is a potent and selective inhibitor of Aurora A with IC50 of 4 nM.

Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.U0126-EtOH is a highly selective inhibitor of MEK1 and MEK2 with IC50 of 0.07 μM and 0.06 μM, respectively.

ZM-447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively.GDC-0879 is a novel potent, selective B-Raf inhibitor for B-RafV600E with IC50 of 0.13 nM.

LY294002 is a PI3K inhibitor for p110α, p110δ and p110β with IC50 of 0.5 μM, 0.57 μM and 0.97 μM, and also blocks autophagosome formation.OSU-03012 is a potent inhibitor of recombinant PDK-1 with IC50 of 5 μM.

Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.TAE684 is a potent and selective ALK inhibitor with IC50 of 3 nM.

BI 2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM.LY315920 (Varespladib) is a potent and selective secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM.

XL880 (GSK1363089, EXEL-2880) is an ATP-competitive inhibitor of MET and KDR with IC50 of 0.4 nM and 0.9 nM, respectively.SGX-523 is a selective Met inhibitor with IC50 of 4 nM.

GSK690693 is a pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 2 nM, 13 nM, and 9 nM, respectively.JNJ-38877605 is an ATP-competitive inhibitor of c-Met with IC50 of 4 nM.

Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of human and rabbit cathepsin K with IC50 of 0.2 nM and 1 nM , respectively.PD 0332991 is a highly selective inhibitor of CDK4/cyclin D1 and CDK6/cyclin D2 with IC50 of 11 nM and 16 nM, respectively.

Triciribine (TCN, API-2) is a DNA synthesis inhibitor and also inhibits Akt and HIV-1 with IC50 of 130 nM and 20 nM, respectively.XL147 (SAR245408) is a selective and reversible class I PI3K inhibitor for wild type and mutant p110α with IC50 of 40 nM and 40 nM, respectively.

XL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM.

TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.

MGCD0103 (Mocetinostat) is a potent HDAC inhibitor for HDAC1, HDAC2 and HDAC3 with IC50 of 0.15 μM, 0.29 μM and 1.66 μM, respectively.

Abiraterone (CB-7598) is a potent CYP17 inhibitor with IC50 of 2 nM.SRT1720 is a selective SIRT1 activator with EC1.5 of 0.16 μM.

YM155 is a potent IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase) inhibitor for survivin with IC50 of 0.54 nM.INO-1001 is a potent inhibitor of PARP with IC50 of 50 nM and a mediator of oxidant-induced myocyte dysfunction during reperfusion.

MLN8237 (Alisertib) is a selective Aurora A inhibitor with IC50 of 1.2 nM.AT9283 is a potent pan-Aurora inhibitor for Aurora A, Aurora B, JAK3, JAK2 and Abl with IC50 of 3 nM, 3 nM, 1.1 nM, 1.2 nM and 4 nM, respectively.

Pemetrexed disodium (Alimta) is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.BMS-582664 is an oral VEGFR/FGFR inhibitor for VEGFR2, Flk1, VEGFR1 and FGFR1 with IC50 of 25 nM, 89 nM, 380 nM and 148 nM, respectively.

ADL5859 HCl is a δ-opioid receptor agonist with Ki of 0.8 nM.Andarine (GTX-007) is a selective nonsteroidal androgen receptor (AR) agonist with Ki of 4 nM.

17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50of 5 nM.17-DMAG (Alvespimycin, KOS-1022, NSC 707545) is a potent HSP90 inhibitor with IC50 of 62 nM.

AG-490 (Tyrphostin B42) is an inhibitor of EGFR, ErbB2 and JAK2 with IC50 of 0.1 μM, 13.5 μM, and ~10 μM, respectively.Ivacaftor (VX-770, Kalydeco) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.

SNS-032 is a novel, potent and selective CDK inhibitor of CDK2, CDK7 and CDK9 with IC50 of 38 nM, 62 nM and 4 nM, respectively. Cyclopamine is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM.

AZD1152-HQPA (Barasertib) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM.Docetaxel, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules.

Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.Paclitaxel (Taxol, Onxol, Nov-Onxol) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

PLX-4720 is a potent and selective inhibitor of B-RafV600E and c-Raf-1Y340D/Y341D with IC50 of 13 nM and 6.7 nM, respectively.Roscovitine (Seliciclib, CYC202, R-roscovitine) is a potent and selective CDK inhibitor for Cdc2/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p53 with IC50 of 0.65 μM, 0.7 μM, 0.7 μM and 0.16 μM, respectively.

SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3.4 nM, respectively.S3I-201 (NSC 74859) is a Stat3 inhibitor with IC50 of 86 μM.

Capecitabine is a tumor-selective fluoropyrimidine carbamate which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU.MK-8245 is an inhibitor of stearoyl-CoA desaturase (SCD) which targets the liver with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1.

Ganetespib is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells.TRAM-34 is a selective and potent inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1) with Kd of 20 nM.

AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells.E7080 (Lenvatinib) is a multi-target inhibitor of VEGFR2 and VEGFR3 with IC50 of 4 nM and 5.2 nM, respectively.

ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules.Cisplatin is an inorganic and water-soluble platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts.

CP-724,714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM and also inhibits EGFR with IC50 of 6.4 μM.

TGX-221 is a potent, selective PI3K inhibitor for p110β with IC50 of 8.5 nM.WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM, respectively.

CYC116 is a potent inhibitor of Aurora A/B and VEGFR with Ki of 8.0 nM/9.2 nM and 44 nM, respectively.JNJ 26854165 (Serdemetan) is an orally bioavailable HDM2 (an E3 ligase) antagonist.

WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFRL858R and EGFRL858R/T790M with IC50 of 2 nM and 8 nM, respectively. Ostarine (GTx-024, MK-2866, Enobosarm, S-22) is a selective androgen receptor modulator (SARM) with Ki of 3.8 nM.

BIIB021 is a novel inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectivley.PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM.

Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor.

XAV-939 is a selective Wnt β-catenin-mediated transcription inhibitor for TNKS1 and TNKS2 with IC50 of 11 nM and 4 nM, respectively.ENMD-2076 is a selective inhibitor of Aurora A and Aurora B with IC50 of 14 nM and 350 nM and also inhibits Flt3, Flt4 and VEGFR2 with IC50 of 1.86 nM/15.9 nM and 58.2 nM, respectively.

Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM.Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.

BIBR 1532 is a potent and selective telomerase inhibitor with IC50 of 100 nM.

Valproic acid sodium salt (Sodium valproate) is a HDAC inhibitor with IC50 of 0.4 mM and also inhibits GABA-transaminase or succinicsemialdehyde dehydrogenase.

PIK-90 is a potent and cell permeable inhibitor of p110α, p110β, p110γ and p110δ with IC50 of 11 nM, 350 nM, 18 nM and 58 nM, respectively.

Anastrozole inhibits the enzyme aromatase.Substance P antagonists (SPA).

Bicalutamide (Casodex, Cosudex, Calutide, Kalumid) is an androgen receptor (AR) antagonist with IC50 of 0.16 μM.Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.094 nM.

Raltitrexed (Tomudex) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth.

CUDC-101 is a potent multi-target inhibitor targeting HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, respectively.TAK-700 (Orteronel) is a potent and highly selective rat and human 17,20-lyase inhibitor with IC50 of 54 nM and 38 nM, respectively.

Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.Finasteride is an inhibitor of steroid Type II 5α-reductase.

Irinotecan (Camptosar, Campto, CPT-11) is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.Cladribine (Leustatin, Litak, 2CDA) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.

Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively.Dimesna is an uroprotective agent used to decrease urotoxicity.

Dutasteride is a 5-alpha-reductase inhibitor PIK-75 is a selective and competitive inhibitor of p110α with IC50 of 5.8 nM and also potently inhibits DNA-PK with IC50 of 2 nM.

Bisoprolol is a selective type β1 adrenergic receptor blocker

Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.Adrucil (Fluorouracil) is an DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS).

Abitrexate (Methotrexate) is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.Bendamustine HCL (Ribomustin, Treanda, SDX-105) is a DNA-damaging agent with IC50 of 50 μM.

Nelarabine (Arranon, 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.Bleomycin sulfate (Blenoxane) is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.

Carboplatin is a DNA synthesis inhibitor by binding to DNA and interfering with the cell's repair mechanism.PFI-1 is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM.

This agent inhibited cell proliferation of NCI-H727 with IC50 at 9.3 nM.Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase

YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM.OSI-930 is a potent inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck with IC50 of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM, respectively.

Dacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various cancers.Epirubicin HCl, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase.

Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity.

KU-0063794 is a potent and highly specific mTOR inhibitor for both mTORC1 and mTORC2 with IC50 ~10 nM.Raloxifene is estrogen antagonists, inhibits human cytosolic aldehyde oxidase-catalyzed phthalazine oxidation activity with IC50 of 5.7 nM.

Idarubicin HCl (Idamycin, Zavedos, 4-demethoxydaunorubicin) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.

Topotecan (Hycamtin, NSC 609699) is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM, respectively.2-Methoxyestradiol is a tubulin polymerization inhibitor and also decreases HIF-1 activity.

AG-1024 (Tyrphostin) is a specific IGF-1R and IR inhibitor with IC50 of 0.4 μM and 0.1 μM, respectively.Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM.

Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.Vincristine is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM.

Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.MP-470 (Amuvatinib) is a potent and multi-targeted inhibitor of c-KitD816H, PDGFαV561D and Flt3D835Y with IC50 of 10 nM, 40 nM and 81 nM, respectively.

Vinblastine inhibits microtubule formation and supresses nAChR activity with IC50 of 8.9 μM.JNJ-7706621 is a potent and multi-target inhibitor for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, Aurora A and Aurora B with IC50 of 9 nM, 4 nM, 3 nM, 11 nM and 15 nM, respectively.

MDV3100 is an androgen-receptor (AR) antagonist with IC50 of 36 nM.

Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.Thalidomide inhibits an E3 ubiquitin ligase， which is a CRBN-DDB1-Cul4A complex.

AV-951 (Tivozanib, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM and also inhibits PDGFR and c-Kit with IC50 of 1.72 nM and 1.63 nM, respectively.

Dienogest is an orally active synthetic progesterone (or progestin).

Rufinamide, a triazole derivative, is an anticonvulsant medication.Posaconazole (Noxafil) is a sterol C14ɑ demethylase inhibitor with an IC50 of 0.25 nM.

A novel platelet inhibitor Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.

AMG-073 HCl (Cinacalcet hydrochloride) represents a new class of compounds for the treatment of hyperparathyroidism.Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM.

BMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectively.PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM.

WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM.PLX4032 (Vemurafenib, RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM.

IC-87114 is a selective inhibitor of PI3Kδ with IC50 of 0.5 μM.BX795 is a potent and specific TBK1, IKKε and PDK-1 inhibitor with IC50 of 6 nM, 41 nM and 111 nM, respectively.

BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM.Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.

Aniracetam is a nootropics and neuroprotective drug.Asenapine ihibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.

Benazepril is a medication used to treat high blood pressure.Biperiden is an antiparkinsonian agent of the anticholinergic type.

Camptothecin (Camptohecine, 20-(S)-Camptothecin, CPT, NSC100880) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM.Carmofur (INN) is a pyrimidine analogue used as an antineoplastic agent.

Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Cetirizine Dihydrochloride is an antihistamine.

Cilnidipine is a calcium channel blocker.Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake.

Epothilone A is a Taxol-like microtubule-stabilizing agent with EC0.01 of 2 μM.Floxuridine (Fludara) is a prodrugs of floxuridine and an oncology agent with an GI50 of 5.1 μM for the inhibition of MDCK/PEPT1.

Ftorafur is a substance being used in the treatment of some types of cancer.Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer.

Megestrol Acetate is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HegG2.Mercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

A potent nitrogen-containing bisphosphonates.It inhibited proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 μM.Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.

AMG-208 is a highly selective c-Met inhibitor with IC50 of 9.3 nM.Costunolide inhibits FPTase with IC50 of 20 μM and also inhibits telomerase with IC50 of 90 μM and 65 μM in MCF-7 and MDA-MB-231 cells.

Dexamethasone is an anti-inflammatory and immunosuppressant.Doxazosin mesylate is an alpha-1 adrenergic receptor blocker.

Ellagic acid has antiproliferative and antioxidant property.Etodolac (Lodine) is a COX inhibitor with an IC50 of 53.5 nM.

Etomidate is a GABAA receptors agonist at GABAA receptors.Flumazenil is a benzodiazepine antagonist.

Fluoxetine HCl is an antidepressant of the selective serotonin reuptake inhibitor (SSRI)class.Flupirtine maleate is the salt form of Flupirtine, which is a non-opioid, centrally acting analgesia, muscle relaxation and neuroprotection.

Fluvoxamine maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI).Gabapentin Hydrochloride is a GABA analogue.

Galanthamine (Razadyne, Reminyl) is an AChE inhibitor with IC50 of 14 nM.Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.

Glimepiride is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.Granisetron HCl is a serotonin 5-HT3 receptor antagonist

TG100-115 is a potent and dual selective inhibitor for PI3Kγ and PI3Kδ with IC50 of 83 nM and 235 nM, respectively.

Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively.

Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid.Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

GSK1059615 is a novel and dual inhibitor of PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR with IC50 of 0.4 nM, 0.6 nM, 2 nM, 5 nM and 12 nM, respectively.MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met, VEGFR1, VEGFR2, VEGFR3, Ron, and Tie2 with IC50 of 1 nM, 3 nM, 3 nM, 4 nM, 2 nM and 7 nM, respectively.

Rigosertib (Estybon, Novonex, ON-01910) is a non-ATP-competitive inhibitor of PLK1 (Polo-like kinase 1) with IC50 of 9 nM.Ki8751 is a potent and selective inhibitor of VEGFR2, PDGFRα and c-Kit with IC50 of 0.9 nM, 67 nM and 40 nM, respectively.

Epothilone B is a Taxol-like microtubule-stabilizing agent with EC0.01 of 1.8 μM.BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM.

Amonafide (NSC-308847) is a selective topoisomerase II inhibitor.Dorzolamide HCl is a carbonic anhydrase inhibitor.

Gestodene is a progestogen hormonal contraceptive.Drospirenone is a synthetic progestin that is an analog to spironolactone.

INCB018424 is a JAK family inhibitor for JAK1, JAK2 and JAK3 with IC50 of 2.7 nM, 4.5 nM and 322 nM, respectively.It was developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.

Lopinavir (ABT-378) is a potent HIV protease inhibitor with Ki of 1.3 pM.Mianserin is a psychoactive agent of the tetracyclic antidepressant.

Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth.Mizoribine (Bredinin) is an imidazole nucleoside and an immunosuppressive agent with an IC50 of approximately 100 μM.

Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.Nafamostat is an anticoagulant.

Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.Omeprazole(Prilosec) is a proton pump inhibitor used in the treatment of dyspepsia.

Ondansetron is a serotonin 5-HT3 receptor antagonist. Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.

Pelitinib (EKB-569) is a potent EGFR inhibitor with IC50 of 38.5 nM.Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects.

Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant.Stavudine is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.

Tenofovir disoproxil fumarate belongs to nucleotide analogue reverse transcriptase inhibitors (nRTIs). Tenofovir blocks reverse transcriptase and hepatitis B virus infections.

Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.Alfuzosin(Uroxatral) is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).

AS-605240 is a novel, potent and selective PI3Kγ inhibitor with IC50 of 8 nM.Clopidogrel (Plavix) is an oral, thienopyridine class antiplatelet agent.

Staurosporine (AM-2282) is a potent PKC inhibitor with IC50 of 2.7 nM.Droxinostat (CMH, 5809354) is a selective inhibitor of HDAC3, HDAC6 and HDAC8 with IC50 of 16.9 μM, 2.47μM and 1.46 μM, respectively.

Ranolazine(Ranexa), is an antianginal medication.Repaglinide is for the treatment of type II diabetes.

Rolipram is a PDE4-inhibitor and an anti-inflammatory agent.Sildenafil citrate is an agent used to treat erectile dysfunction and pulmonary arterial hypertension (PAH).

Sumatriptan succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.Tianeptine is a selective serotonin reuptake enhancer (SSRE) compound used for treating major depressive episodes.

Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.Topiramate is an anticonvulsant compound.

Varenicline is a prescription medication used to treat smoking addiction.Venlafaxine is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI).

Voriconazole (VFEND) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections.

Zileuton (ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation.

Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM.Ispinesib (SB-715992, CK0238273) is a potent, specific and reversible inhibitor of KSP (HsEg5) with Ki of 1.7 nM.

Tipifarnib (Zarnestra, R115777) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM.PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, repectively.

Cilomilast (SB-207499) is a potent LPDE4 and HPDE4 inhibitor with IC50 of 100 nM and 120 nM, respectively.Zibotentan (ZD4054) is a specific Endothelin A (ETA) antagonist with IC50 of 21 nM.

Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM.Thiazovivin (Tzv) is a novel ROCK inhibitor with IC50 of ~0.5 μM.

SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM, respectively.Ofloxacin is a synthetic broad-spectrum antimicrobial agent.

Moxifloxacin(Avelox, Avalox) is a fourth generation synthetic fluoroquinolone antibacterial agent.Alfacalcidol is a non-selective VDR activator medication.

TSU-68 (SU6668, Orantinib) is a potent inhibitor of Flk-1/KDR, FGFR1 and PDGFRβ with Ki of 2.1 μM, 1.2 μM, and 8 nM, respectively.Safinamide Mesylate is mesylate salt of Safinamide, which selectively and reversibly inhibits MAO-B with IC50 of 0.45 μM.

GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM, respectively.AS703026 is a highly selective and potent non-competitive inhibitor of MEK1/2 with IC50 of 5-11 nM.

SB 525334 is a potent and selective inhibitor of TGF-β1 (ALK5) with IC50 of 14.3 nM.

VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM.LY335979 (Zosuquidar) is a potent modulator of P-glycoprotein-mediated multidrug resistance with Ki of 60 nM.

BMS-790052 is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM.MC1568 is a selective HDAC inhibitor with IC50 of 220 nM.

HMN-214 (IVX-214) is a potent inhibitor of Polo-like kinase (Plk)1 with IC50 of 118 nM.AEE788 is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM and also inhibits VEGFR2 and Flt with IC50 of 77 nM and 59 nM, respectively.

PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM, respectively.Naratriptan (Amerge) is a triptan agent that is used for the treatment of migraine headaches.

PIK-93 is a novel and potent inhibitor of PI3Kγ and PI4KIIIβ with IC50 of 16 nM and 19 nM, respectively.AP24534 is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively.

Fludarabine (Fludara, F-ara-A, NSC 118218) is a STAT1 activation inhibitor and a DNA synthesis inhibitor.LY2228820 is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM.

Pralatrexate(Folotyn) is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines.NVP-BEP800 is a novel, fully synthetic HSP90β inhibitor with IC50 of 58 nM.

Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively.Dyphylline(Dilor, Lufyllin, diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects.

Perindopril Erbumine (Aceon) is a potent ACE) inhibitor with IC50 of 1.05 nM.Irbesartan (Avapro, SR-47436, BMS-186295) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.

Tadalafil is a PDE-5 inhibitor with IC50 of 1.8 nM.SB939 is a potent HDAC inhibitor with IC50 of 40-140 nM.

Ibuprofen Lysine(Motrin) is a non-steroidal anti-inflammatory drug.CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively.

CHR-2797 is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively.XL765 is a dual inhibitor of mTOR/PI3k for mTOR, p110α, p110β, p110γ and p110δ with IC50 of 157 nM, 39 nM, 113 nM, 9 nM and 43 nM, respectively.

AT7519 is a novel multi-CDK inhibitor for CDK1/cyclin B, CDK2/Cyclin A, CDK3/Cyclin E, CDK4/Cyclin D1, CDK5/p35 and CDK6/Cyclin D3 with IC50 of 210 nM, 47 nM, 360 nM, 100 nM, 13 nM and 170 nM, respectively.MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM.

AC220 (Quizartinib) is a potent and selective inhibitor of Flt3ITD and Fltwt with IC50 of 1.1 nM and 4.2 nM, respectively.LY2811376 is a non-peptidic BACE1 inhibitor with IC50 of 239 nM/249 nM and also decreases the Aβ secretion with EC50 of ~300 nM.

Hesperadin inhibits Aurora B and T. brucei Aurora kinase-1 (TbAUK1) with IC50 of 250 nM and 40 nM, respectively.BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM.

BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM.

Oligomycin A is a specific inhibitor of complex V (ATP synthase) of the electron transport chain.

AZD7762 is a novel CHK1 and CHK2 inhibitor with IC50 of 5 nM and <10 nM, respectively.

R406 (free base) is a Syk inhibitor with IC50 of 41 nM.CP 673451 is a potent PDGFR-β inhibitor with an IC50 of 1 nM.

DMXAA (ASA404) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM, respectively.Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.

Saxagliptin (BMS-477118, Onglyza) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM.

AM-1241 is a selective CB2 agonist with Ki of 3.4 nM.SB-408124 (Tocris-1963) is a non-peptide antagonist for OX1 with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively.

Dapagliflozin is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM.Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.

Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM.AZD8055 is a novel ATP-competitive inhibitor of mTOR with IC50 of 0.8 nM.

PHT-427 is a dual Akt and PDPK1 inhibitor with Ki of 2.7 μM and 5.2 μM, respectively.KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM and also inhibits PDGFRα/β with IC50 of 965 nM/9850 nM.

AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and S6K with IC50 of 32 nM/17 n/47 nM and 85 nM, respectively.BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively.

VX-809 is a CFTR modulator with EC50 of 0.1 μM.Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM.

PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor.KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.

BS-181 is a highly selective CDK inhibitor for CDK7 with IC50 of 21 nM.Fasudil is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively.

BIRB 796 (Doramapimod) is a highly selective p38α MAPK inhibitor with Kd of 0.1 nM.Tie2 kinase inhibitor is a potent and selective Tie2 inhibitor with IC50 of 0.25 μM.

Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.PD 0332991 (Palbociclib) Isethionate is the isethionate of PD 0332991, a highly specific inhibitor of CDK4 and CDK6 with IC50 of 11 nM and 16 nM, respectively.

H 89 2HCl is a mutiple-targeted inhibitor for S6K1, MSK1, PKA, ROCKII, PKBα and MAPKAP-K1b with IC50 of 80 nM, 120 nM, 135 nM, 270 nM, 2600 nM and 2800 nM, respectively. TWS119 is a GSK-3β inhibitor with IC50 of 30 nM.

Ubenimex is a competitive aminopeptidase B inhibitor with an IC50 of 100 mg/ml for K562 cells.Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.

Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, respectively. Semagacestat also inhibits Notch signaling with IC50 of 14.1 nM.Olmesartan medoxomil (Benicar) is a compound which is hydrolyzed to olmesartan that is a selective AT1 subtype angiotensin II receptor antagonist.

Rizatriptan Benzoate(Maxalt) is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.Pyridostigmine Bromide(Mestinon) is a parasympathomimetic and a reversible cholinesterase inhibitor.

Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity.

Riluzole(Rilutek) is a drug used to treat amyotrophic lateral sclerosis. Risperidone(Risperdal) is an atypical antipsychotic used to treat schizophrenia.

Acetylcysteine is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose. Alendronate (Fosamax) is a farnesyl diphosphate synthase inhibitor with IC50 of 460 nM.

Naproxen (Aleve, Anaprox) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.Nitazoxanide(Alinia, Annita) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)

Orlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice.Allopurinol (Zyloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.

Allopurinol Sodium(Aloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.Zafirlukast is a leukotriene receptor antagonist (LTRA). (IC50=0.6μM, IC50=7.0 µM for CYP2C9)

Ibuprofen (Advil, Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.Amprenavir is a HIV protease inhibitor with IC50 of 14.6 ng/mL in wild-type HIV isolates.

Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.

Ketoprofen (Actron) is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.

Ketorolac (Ketorolac tromethamine, Toradol) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.Cytarabine (Cytosine arabinoside, AraC) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells.

Zolmitriptan(Zomig) is a selective serotonin receptor agonist.Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.

Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM.Estrone is an estrogenic hormone.

Flucytosine (5-Fluorocytosine, 5-FC, Ancobon) is an antifungal drug with IC50 of 0.93 μM in C. albicans.Aminoglutethimide (AMG, Cytadren) is an aromatase inhibitor with IC50 of 10 μM.

Aminophylline(Phyllocontin, Truphylline) is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.Carbamazepine (Carbatrol) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.

Torsemide(Demadex) is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 ± 0.17 μM.Didanosine(Videx, Videx EC) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.

Divalproex sodium consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form.Emtricitabine (Emtriva) is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM.

Lamivudine(Epivir) is a potent nucleoside analog reverse transcriptase inhibitor with an IC50 of 2.7 mM.Eplerenone is an aldosterone antagonist with an IC50 of 0.36 μM.

Piroxicam (Feldene) is a non-selective COX inhibitor with an IC50 of 6 mM.Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites.

Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).

Paliperidone(Invega) is an atypical antipsychotic.Telmisartan (Micardis) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.

Nevirapine(Viramune) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.Esomeprazole magnesium(Nexium) is a proton pump inhibitor to reduce gastric acid secretion.

Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy.Nisoldipine (Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.

Oxybutynin(Ditropan) is an anticholinergic medication used to relieve urinary and bladder difficulties.Quetiapine fumarate(Seroquel) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.

Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.Thioguanine is a purine antimetabolite widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.

Toremifene Citrate(Fareston, Acapodene) is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body.Azacitidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases.

Bacitracin zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.Simvastatin (Zocor) is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM .

Ramipril (Altace) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.Ranitidine (Zantac) is a histamine H2-receptor antagonist with IC50 of 3.3 ± 1.4 μM.

Acadesine results in accumulation of ZMP, which mimics both activating effects of AMP on AMPK and AMPKK.The chemical compound acetylcholine (ACh) is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.

Nifedipine(Adalat), a potent vasodilator agent with calcium antagonistic action.Amlodipine (Norvasc) is a long-acting calcium channel blocker with an IC50 of 1.9 nM.

Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM.Betaxolol hydrochloride (Betoptic) is a β1 adrenergic receptor blocker with IC50 of 6 μM.

Proparacaine HCl is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.Pranlukast is a selective cysteinyl leukotriene receptor antagonist.

Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.

Lomustine inhibits cancer cells by damaging the DNA and stops cells from dividing.

Butoconazole nitrate is an anti-fungal agent for IL-2, TNFα, IFN and GM-CSF with IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively.

Azithromycin (Zithromax) is an antibiotic for inhibition of parasite growth with IC50 of 8.4 μM.Flubendazole (Flutelmium) is an anthelmintic agent for MDAY-D2 cells with IC50 of 3 nM.

Cimetidine(Tagamet), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.

Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM.

Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor.

Felodipine (Plendil) is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM.

Nizatidine is a histamine H2-receptor antagonist with and IC50 of 6.7 nM for AChE.Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.

Valsartan (Diovan) is an angiotensin II receptor antagonist with IC50 of ranging from 39.5 to 116 μMTropisetron hydrochloride is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.

Diclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.Amlodipine(Norvasc) is a long-acting calcium channel blocker with an IC50 of 1.9 nM.

Flutamide (Eulexin) is an oral nonsteroidal antiandrogen agent primarily used to treat prostate cancer.Fluvastatin sodium inhibits HMG-CoA reductase activity with IC50 of 8 nM.

Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor- and M3 receptor-mediated currents with IC50 of 11.4 ¦ÌM and 6.0 ¦ÌM, respectively.

Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.Irsogladine is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.

Enalapril maleate (Vasotec), the active metabolite of enalapril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II.Metformin hydrochloride(Glucophage) is a biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification.

Nefiracetam (Translon) is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions.Nicorandil(Ikorel) is potassium channel activator.

Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding.Meglumine is an amino sugar derived from sorbitol for THP-1 cells with IC50 of 22 μg/mL.

Methscopolamine (Pamine) is a muscarinic acetylcholine receptor blocker.

Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry.

Adenine sulfate is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.Adenine hydrochloride is a hydrochloride salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.

Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker.

Procarbazine hydrochloride (Matulane) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound used as an antineoplastic agent.Ondansetron (Zofran) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.

Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM.Elvitegravir (EVG, JTK-303/GS-9137) is a HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.

Maraviroc (Selzentry, UK-427857, Celsentri) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM, respectively.Raltegravir (MK-0518, Isentress) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectivly.

Pyrimethamine is a dihydrofolate reductase(DHFR) inhibitor with an IC50 of 15.4 nM.Pramipexole is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM.

PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM.PF 573228 is a inhibitor of FAK with IC50 of 4 nM.

BMS265246 is a potent and selective CDK inhibitor for CDK1/cyclin B and CDK2/cyclin E with IC50 of 6 nM and 9 nM, respectively.Suplatast tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.

ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, a selective inhibitor of Aurora A and Aurora B with IC50 of 14 nM and 350 nM and also inhibits Flt3, Flt4 and VEGFR2 with IC50 of 1.86 nM, 15.9 nM and 58.2 nM, respectively.

Bifonazole is an antifungal agent and a prostatic aromatase activity inhibitor with IC50 of 1.6 μM.

Metoprolol tartrate is a cardioselective β-adrenergic receptor blocker with IC50 of 42 ng/mL.Etidronate (Didronel) is a human protein tyrosine phosphatase inhibitor with IC50 of 0.2 μM.

Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Tropicamide is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.

Tolfenamic acid is a COX-2 inhibitor with IC50 of 0.2 μM.Pranoprofen is a PGE2 inhibitor with IC50 of 7.5 μM.

Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.

Amiodarone HCl is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM.

Formoterol hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist to β2 and β1 receptors with pKd of 8.12 and 5.58, respectively.

Ketotifen fumarate (Zaditor) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.Urapidil hydrochloride is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.

Candesartan cilexetil (Atacand) is a specific nonpeptide Ang II receptor (ATR) antagonist and the prodrug of candesartan which is an ATR antagonist with an IC50 of 15 μg/kg

Cyproterone acetate is an androgen receptor (AR) antagonist with IC50 of 7.1 nM.

Moexipril hydrochloride is a potent orally active non-sulfhydryl angiotensin converting enzyme inhibitor (ACE) with IC50 of 0.041 ¦ÌM, which is used for the treatment of hypertension and congestive heart failure.

Adiphenine is a nicotinic receptor inhibitor with IC50 of 15 ¦ÌM, used as an antispasmodic drug.

Gabexate is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation.

Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14.5 μM.Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.

Flunarizine dihydrochloride is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.Rebamipide is a cholecystokinin type 1 (CCK1) receptor inhibitor for inhibiting [125I]BH-CCK-8S with IC50 of 37.7 μM.

Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM.

Phentolamine mesilate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM.Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.

Memantine hydrochloride (Namenda) is a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively.

Cyproheptadine hydrochloride (Periactin) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM.Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.

Pioglitazone hydrochloride (Actos) is a hydrochloride salt form of pioglitazone which is a cytochrome P450 (CYP)2C8 and CYP3A4 enzymes inhibitor for CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively.Lornoxicam (Xefo) is a COX-1 and COX-2 inhibitor with IC50 of 5 nM and 8 nM, respectively.

Strontium ranelate (Protelos) is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.Captopril (Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.

Orphenadrine citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.

Hytrin (terazosin) is an alpha-adrenergic blocker used to treat high blood pressure and enlarged prostate.Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent).

Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.Moxonidine is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent.

Ozagrel hydrochloride is a selective thromboxane A2 synthetase enzyme inhibitors with IC50 of 11 nM, used as antiasthmatic agent.Mitiglinide is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.

Rosiglitazone is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells. Lisinopril is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.

Atorvastatin (Lipitor) is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol.Famotidine is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.

Cleviprex (Clevidipine) is a dihydropyridine calcium channel blocker use as agent for the reduction of blood pressure.

Cilazapril is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.

Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.

Ivabradine, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.Rivastigmine, a cholinesterase inhibitor with IC50 of 5.5 μM, ues as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.

Dexmedetomidine is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.

Detomidine produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.Fosinopril sodium (Monopril) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

Almotriptan malate (Axert) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.Ambrisentan, a highly selective antagonist of the endothelin-1 type A receptor with IC50 of 18 nM, is indicated for the treatment of pulmonary arterial hypertension (PAH).

Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.Temocapril HCl is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

Rasagiline mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.

Naltrexone is an opioid receptor antagonist with IC50 of 8 nM used primarily in the management of alcohol dependence and opioid dependence.

Lapatinib, used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.

Naftopidil (Flivas) is a selective α1-adrenergic receptor antagonist or alpha blocker with a Ki of 58.3 nM.S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM.

Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM.Atropine sulfate monohydrate is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM.

Roflumilast (Daxas) is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM.Gabapentin (Neurontin) is a pharmaceutical agent, specifically a GABA analogue.

AZD8330 (ARRY-424704) is a MEK 1/2 inhibitor with IC50 of 7 nM.GSK-1292263 is a novel GPR119 agonist.

Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM, respectively.LDE225 (NVP-LDE225) is a smoothened antagonist with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.

CGS 21680 hydrochloride is an A2A adenosine receptor agonist with an Ki of 27 nM.BIBR-1048 (Dabigatran) is an anticoagulant from the class of the direct thrombin inhibitors.

LY2608204 activates glucokinase (GK) with EC50 of 42 nM.LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.

LY2940680 binds to the Smo receptor and potently inhibits Hh signaling.KW-2449 potently inhibits Flt3, Abl and Aurora A with IC50 of 6.6 nM, 14 nM and 48 nM, respectively.

Tebipenem pivoxil(L-084) is a novel oral carbapenem antibiotic with an IC50 of 100 μg/ml for human CYP isoformsPF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki of 20 nM and IC50 of 160 nM.

PD 128907 HCl is a potent and selective dopamine D2/D3 receptors agonist.Rosuvastatin calcium is an competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM.

ITF2357 (Givinostat) is a potent inhibitor of HDAC with IC50 of 7.5-16 nM.AG14361 is a potent inhibitor of PARP1 with Ki of < 5 nM.

LY2784544 is selective to V617F mutant JAK2 with IC50 of 55 nM in Ba/F3 cells.MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM, respectively.

MLN9708 is a selective inhibitor of chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM. SB 743921 is a KSP inhibitor with IC50 of 0.2 nM, 0.07 nM, 1.7 nM, 0.06 nM and 14.4 nM in SKOV3, Colo205, MV522, MX1 and P388 cell lines, respectively.

BGJ398 (NVP-BGJ398) is a potent and selective inhibitor of FGFR1, FGFR2 and FGFR3 with IC50 of 0.9 nM, 1.4 nM and 1 nM, respectively.AST-1306 is a novel irreversible inhibitor of EGFR and ErbB4 with IC50 of 0.5 nM and 0.8 nM, respectively.

SB505124 is a selective inhibitor of ALK4 and ALK5 with IC50 of 129 nM and 47 nM, respectively.Avasimibe inhibits ACAT and CYP2C9 with IC50 of 3.3 μM and 2.9 μM, respectively.

AZD8931 is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM, respectively.GSK461364 inhibits purified Plk1 with Ki of 2 nM.

R406 is a potent Syk inhibitor with IC50 of 41 nM and also potently inhibits Flt3.SGI-1776 is a novel ATP competitive inhibitor to Pim1, Pim2 and Pim3 with IC50 of 7 nM, 363 nM and 69 nM, respectively.

Aliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM.BMS794833 is a potent ATP competitive inhibitor of Met and VEGFR2 with IC50 of 1.7 nM and 15 nM, respectively.

NVP-BHG712 is a specific inhibitor of c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM and also inhibits EphB4 and VEGFR2 with ED50 of 25 nM and 4.2 μM, respectively.OSI-420 is an active metabolite of Erlotinib which is an orally active EGFR inhibitor for inhibition of human EGFR and EGFR autophosphorylation with IC50 of 2 nM and 20 nM, respectively.

R935788 (Fostamatinib disodium, R788) is a Syk inhibitor with IC50 of 41 nM.PIK-293 is a PI3-K inhibitor for p110α, p110β, p110δ and p110γ with IC50 of 100 μM, 25 μM, 0.24 μM and 10 μM, respectively.

Formestane(Lentaron(R)) is a second generation selective aromatase inhibitor with an IC50 of 80 nM.

Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.

Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.

Flunixin meglumine is a potent inhibitor of the enzyme cyclooxygenase used as analgesic agent with anti-inflammatory and antipyretic activity. Vinpocetine is a selectively inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease.

Blonanserin is a novel atypical antipsychotic agent with potent dopamine D2 (Ki, 14.8 nM) and serotonin 5-HT2(Ki, 3.98 nM) receptors antagonist properties.

Cisatracurium besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.

Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.

AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, respectively.DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.

Mubritinib (TAK 165) is a potent inhibitor of ErbB2 with IC50 of 6 nM.Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.

PP242 is a selective mTOR inhibitor with IC50 of 8 nM.CYT387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50 of 11 nM and 18 nM, respectively.

SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM.Apatinib (YN968D1) is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM.

Tosyl-L-Arginine Methyl Ester (TAME) is an APC inhibitor and also inhibits an E3 ubiquitin ligase called "anaphase-promoting complex/cyclosome (APC/C)".CAL-101 is a selective PI3K class I inhibitor of p110δ with IC50 of 2.5 nM.

PIK-294 is a highly potent and selective p110δ inhibitor with IC50 of 10 nM.Eltrombopag (SB-497115-GR, Promacta, Revolade) is a small molecule agonist of the c-mpl (TpoR) receptor with an IC50 of 0.69 μM for the inhibition of hERG K+ channel tail current.

LY2157299 is a potent TGFβ receptor I (TβRI) inhibitor with IC50 of 56 nM.Telatinib (BAY 57-9352) is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRβ with IC50 of 6 nM/4 nM, 1 nM and 15 nM, respectively.

Ketanserin (Vulketan Gel) is specific 5-HT2A serotonin receptor antagonist with a Ki of 2.5 nM for rat and human 5-HT2A.Esomeprazole sodium (Nexium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.

BI6727 (Volasertib) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM.Palomid 529 (P529) is a PI3K/Akt/mTOR inhibitor for VEGF-A and bFGF with IC50 of 10 nM and 30 nM, respectively.

Fesoterodine fumarate (Toviaz) is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.WP1130 (degrasyn) is a selective deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor and also inhibits Bcr/Abl with IC50 of 1.8 μM.

AR-42 (HDAC-42, OSU-HDAC42) is a pan-HDAC inhibitor with IC50 30 nM.CP-466722 is an potent and reversible ATM inhibitor.

Abiraterone acetate (CB7630, CB 7630, CB-7630) is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM.BKM120 is a selective PI3K inhibitor of p110α, p110β, p110δ and p110γ with IC50 of 52-99 nM, 166 nM, 116 nM and 262 nM, respectively.

CX-4945 is a potent and selective inhibitor of CK2α and CK2α' with IC50 of 1 nM.(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM.

4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.

Apigenin is a potent P450 inhibitor for CYP2C9 with IC50 of 23 pMArbutin(Uvasol, p-Arbutin) is a tyrosinase inhibitor with an IC50 of 1.09 mM.

Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69.Asiatic acid is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.

Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor. Baicalin is a known prolyl endopeptidase inhibitor and affects the GABA receptors.

Cryptotanshinone (CPT) is a STAT3 inhibitor with IC50 of 4.6 μM.Cytisine is a nicotinic acetylcholine receptor agonist.

Hesperetin is a bioflavonoid and, to be more specific, a flavanone.Honokiol is a biphyl neolignan present in the cones, bark, and leaves of Magnolia grandifloris that displays antiangiogenic, antiinflammatory, and antitumor properties due to the inhibitory effect on the PI3K/Akt pathway.

Icariin is a flavonol and PDE5 inhibitor with IC50 of 1.0, 0.75, and 1.1 μM for PDE5A1, A2, and A3, respectively.Luteolin is a PDE4 inhibitor and a general phosphodiesterase inhibitor, and an Interleukin 6 inhibitor.

Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.Neohesperidin is an antioxidant agent with an IC50 of 22.31 μg/ml in the 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay.

Parthenolide ((-)-Parthenolide) is a sesquiterpene lactone which occurs naturally in the plant feverfew(Tanacetum parthenium) and also promotes the ubiquitination of MDM2 and activates p53 cellular functions.Puerarin (Kakonein) is a 5-HT2C receptor and benzodiazepine site antagonist.

Aminoglutethimide (Cytadren) is an anti-steroid drug which inhibits aromatase.Synephrine (Oxedrine) is a compound commonly used for weight loss.

5-Hydroxytryptophan(5-HTP) is decarboxylated to serotonin (5-hydroxytryptamine or 5-HT) by the enzyme aromatic-L-amino-acid decarboxylase with the help of Vitamin B6.Aloin(Barbaloin) is a potent tyrosinase inhibitor with an IC50 of 97 μM for HeLaS3 cells

Dioscin(Collettiside III) is a saponin extracted and isolated from Polygonatum Zanlanscianense Pamp with IC50 of 2.6, 0.8, 7.5, and 4.5 μM for the inhibition of the growth of the MDA-MB-435, H14, HL60, and HeLa cell lines, respectively.

Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 75 nM and 0.19 μM.

Quercetin (Sophoretin) is a PI3K and PKC inhibitor with IC50 of 3.8 μM and 15µg/ml. Naringenin is a flavonoid that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator.

Salidroside (Rhodioloside; Rhodosin) is a glucoside compound with an IC50 of 4.99 ± 0.23 μg/mL for the proliferation of SACC-2 cells.Sodium Danshensu is a mono sodium of danshensu which is a compound isolated from Salvia miltiorrhiza Bge.

Tetrandrine (Fanchinine; Hanfangchin A) is a calcium channel blocker with an IC50 of 38.23± 25.77 μM.Chrysophanic acid (Chrysophanol) is a EGFR/mTOR pathway inhibitor.

Astragaloside A is a pure small molecular compound isolated from Radix Astragali and is commonly used in the treatment of degenerative bone diseases such as osteoporosis. 20-Hydroxyecdysone (Ecdysterone, 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods.

10-Hydroxycamptothecin (10-HCPT, 10-hydroxy-CPT, OHCPT, NSC107124) is a DNA topoisomerase I inhibitor with potent anti-tumor activity.Apocynin (Acetovanillone) is a selective NADPH-oxidase inhibitor with IC50 of 10 μM.

Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.Synephrine HCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.

Tolbutamide is an inhibitor of cAMP with IC50 of 4 mM.Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC).

Equol is an isoflavandiol metabolized from daidzein by bacterial flora in the intestines.Amantadine hydrochloride(Symmetrel) is used to treat or prevent infections of the respiratory tract caused by a certain virus.

Amfebutamone (Bupropion) is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4μM for the reuptake of dopamine and norepinephrine, respectivelyBenserazide is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.

Bupivacaine hydrochloride(Marcain) is a more potent cAMP production inhibitor with an IC50 of 2.3 μMBethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.

Chlorpromazine (Sonazine) is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for nward-rectifying K+ currents and time-independent outward currentsClonidine hydrochloride(Catapres) is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.

Clozapine (Clozaril) is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.Pramipexole (Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.

Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.

Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.Fluocinolone(Flucort-N) acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.

Gallamine triethiodide(Flaxedil) is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.

Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.Loperamide is an opioid-receptor agonist with an ED50 of 0.15 mg/kg.

Manidipine (Manyper) is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM.Manidipine HCl is a HCl salt form of Manidipine which is a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.

Milrinone(Primacor) is a a potent and selective phosphodiesterase 3 inhibitor with an IC50 of 0.42 μM for the inhibition of FIII PDEMitoxantrone HCl is a classic folic acid antagonist.

Nateglinide(Starlix) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.Neostigmine bromide(Prostigmin) is a reversible acetylcholinesterase inhibitor.

Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.Olanzapine(Zyprexa) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.

Olopatadine hydrochloride(Opatanol) is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamineOxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist.

Ozagrel is a potent and selective thromboxane A2 synthetase inhibitor with an IC50 of 4 nM.Pancuronium (Pavulon) is a competitive acetylcholine antagonist with an IC50 of 5.5 ¡À 0.5 nM

Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.Propafenone(Rytmonorm) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.

Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μMRosiglitazone maleate (Avandia) is an anti-diabetic agent in the thiazolidinedione class of agents.

Salbutamol (Albuterol) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.

Scopolamine hydrobromide is a competitive muscarinic acetylcholine receptor with an IC50 of 55.3 ¡À 4.3 nM

Sotalol (Betapace) is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μMSulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax

Tenoxicam(Mobiflex) is a good HO. radicals scavenger with an IC50 of 56.7 μMVardenafil Hydrochloride Trihydrate (Vivanza) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.

Xylazine HCl is α2 class of adrenergic receptor agonist.Maprotiline hydrochloride (Deprilept, Ludiomil, Psymion) is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.

Naphazoline hydrochloride (Naphcon) is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.Epinephrine bitartrate (D02149, Adrenalinium) is alpha- and beta-adrenergic receptor stimulator.

L-Adrenaline (Epinephrine) belongs to a group of the compounds known as catecholamines.DL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands.

Phenytoin sodium (Dilantin) is an inactive voltage-gated sodium channel stabilizer.Phenytoin (Lepitoin; NSC 8722; Phenytek; Phenytoine; Sodanton; Zentropi) is an inactive voltage-gated sodium channel stabilizer.

Alizarin strongly inhibits P450 isoform CYP1A1, CYP1A2 and CYP1B1 with IC50 of 6.2 μM, 10.0 μM and 2.7 μM, respectively.Dopamine hydrochloride (Inotropin) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.

Asaraldehyde (Asaronaldehyde) is natural COX-2 inhibitor.Ritodrine hydrochloride (DU 21220; Miolene; NSC 291565; Pre-Par) is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.

Clomipramine hydrochloride (Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. Phenformin hydrochloride is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class.

Tiotropium Bromide hydrate is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.

Trospium chloride (Sanctura) is a competitive muscarinic cholinergic receptor antagonist.

Tolterodine tartrate (Detrol LA) is a tartrate salt of tolterodine that is a competitive muscarinic receptor antagonist.Azelastine hydrochloride (Astelin) is a potent, second-generation, selective, histamine antagonist.

Daphnetin is an inhibitor of EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively.Clarithromycin (Biaxin, Klacid) is a macrolide antibiotic and a CYP3A4 substrate and inhibitor.

Rosiglitazone (Avandia) is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively.Amiloride hydrochloride dihydrate is a potent epithelial sodium channel blocker.

Clomifene citrate (Serophene) is a selective estrogen receptor modulator.Hydralazine hydrochloride is a hydrochloride salt of hydralazine (Apresoline) that is a direct-acting smooth muscle relaxant with an IC50 of 1.9 mM.

Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.

Phenylephrine hydrochloride is a selective α1-adrenergic receptor agonist.Tetracaine hydrochloride (Pontocaine) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.

Phenacetin is a non-opioid analgesic without anti-inflammatory properties.Zidovudine (Retrovir) is a reverse transcriptase inhibitor.

Quinapril hydrochloride (Accupril) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.

Brompheniramine is a histamine H1 receptors antagonist.Pioglitazone (Actos) is a selective peroxisome proliferator-activated receptor gamma stimulator.

Tolvaptan (OPC-41061) is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28¦ÌM for the inhibition of AVP-induced platelet aggregation.Gliclazide (Diamicron) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 ¡À 30 nM

Acemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.

Dehydroepiandrosterone(DHEA) is a 19-carbon endogenous natural steroid hormone.Mifepristone (Mifeprex, RU-486, RU-38486, Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively.

Lonidamine is an orally administered small molecule hexokinase inactivator with an IC50 of 0.85 mM.

Arecoline is a muscarinic acetylcholine receptor agonist.

Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.

Scopine HCl is the hydrochloride of Scopine, which is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.

Isoprenaline is a non-selective β-adrenoceptor, inhibits the 3H-inositol phosphate accumulation with IC50 of 0.08 μM.

Trazodone is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

Ethisterone is a progestogen hormone being considered to treat prostate cancer.

Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.

TAK-733 is a potent, selective, non ATP-competitive MEK inhibitor with IC50 of 3.2 nM. LDN193189 is a selective inhibitor of ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively.

GSK256066 is a selective PDE4B inhibitor with IC50 of 3.2 pM.AZD5438 is a potent inhibitor of CDK1, CDK2 and CDK9 with IC50 of 16 nM, 6 nM, and 20 nM, respectively.

PP-121 is a multi-target inhibitor of PDGFR, Hck, mTOR, VEGFR2, Src and Abl with IC50 of 2 nM, 8 nM, 10 nM, 12 nM, 14 nM and 18 nM, respectively, and also inhibits DNA-PK with IC50 of 60 nM.OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively.

R788 (Fostamatinib) is a Syk inhibitor with IC50 of 41 nM.LY2603618 (IC-83) is a selective Chk1 inhibitor with potential anti-tumor activity.

Tubastatin A is a potent HDAC6 inhibitor with IC50 of 15 nM.PKI-587 is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM, respectively.

PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM in α7*-expressing SH-EP1 cells.GW3965 is a potent, selective LXR agonist, which exhibits its potency in the LXRα/SRC1 LiSA and LXRα-GAL4 with EC50 of 125 nM and 190 nM, respectively.

URB597 (KDS-4103) is a potent FAAH inhibitor with IC50 of 4.6 nM.BMS-806 (BMS 378806) selectively inhibitis the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.

DCC-2036 is a conformational control inhibitor of Abl1 and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, respectively.CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM.

A66 is a potent and specific p110α inhibitor with IC50 of 32 nM.TAK-875 is a selective GPR40 agonist with EC50 of 14 nM.

NU7441 is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM.SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, respectively.

PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and also inhibits Her-2 degradation with IC50 of 37 nM.GSK2126458 is a highly selective and potent inhibitor of p110α, p110β, p110γ, p110δ, mTORC1 and mTORC2 with Ki of 0.019 nM, 0.13 nM, 0.024 nM, 0.06 nM, 0.18 nM and 0.3 nM, respectively.

5-hydroxymethyl tolterodine (PNU 200577) is a new muscarinic receptor antagonist with Kb of 0.84 nM.MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM in human SH-SY5Y cells.

WYE-125132 is a highly potent, ATP-competitive and specific mTOR inhibitor with IC50 of 0.19 nM.WAY 100635 is a potent and selective 5-HT agonist with IC50 of 0.95 nM.

Clinofibrate inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR) with IC50 of 0.47 mM.Ciprofibrate is a peroxisome proliferator-activated receptor agonist.

PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM.S/GSK1349572 (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM.

WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM.LY310762 is a 5-HT1D antagonist with Ki of ~0.2 μM.

A-674563 inhibits Akt1, PKA and CDK2 with Ki of 11 nM, 16 nM and 46 nM, respectively.AS-252424 is a novel, potent and selective inhibitor of PI3Kγ with IC50 of 33 nM.

PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively. GSK1120212 (JTP-74057, trametinib) is a highly specific and potent MEK1 and MEK2 inhibitor with IC50 of 0.92 nM and 1.8 nM, respectively.

A 922500 is a DGAT-1 inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively.BRL-15572 is a 5-HT1D antagonist with pKi of 7.9.

NSC-207895 suppresses MDMX with IC50 of 2.5 ¦ÌM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulate MDM2, an E3 ligaseFlavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM, and CDK7 with IC50 of 300 nM.

PCI-32765 (Ibrutinib) is a potent and highly selective Btk inhibitor with IC50 of 0.5 nM.AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM.

CAY10505 is a PI3Kγ inhibitor with IC50 of 30 nM.CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM.

CX-5461 selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116 cells. KW-2478 is a nonansamycin HSP90 inhibitor with IC50 of 3.8 nM.

NVP-BSK805 is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM.R547 is a potent and selective CDK inhibitor with Ki and IC50 of 1-3 nM and 80 nM respectively.

WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM.

ADX47273 is a potent and specific mGlu5 antagonist with IC50 of 0.17μM.

BMY 7378 is a multiple inhibitors of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively.TG101209 is a potent inhibitor of JAK2, Flt3 and RET with IC50 of 6 nM, 25 nM and 17 nM, respectively.

WAY-362450 is a potent, selective FXR agonist with EC50 of 4 nM.GDC-0980 (RG7422) is a potent, selective inhibitor of PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ with IC50 of 5 nM, 27 nM, 7 nM, and 14 nM, and also a mTOR inhibitor with Ki of 17 nM.

A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM and inhibits fatty acid synthesis with IC50 of 3.2 μM.RS-127445 is a selective 5-HT2B antagonist with pKi of 9.5 and pIC50 of 10.4.

CH5132799 exhibits a strong inhibitory activity especially against PI3Kα with IC50 of 14 nM and also inhibits mTOR with IC50 of 1.6 µM.KX2-391 (KX01) is a highly selective non ATP-competitive Src inhibitor with GI50 of 9-60 nM in cancer cell lines .

GSK1838705A is a potent inhibitor of IGF-1R, IR and ALK with IC50 of 2.0 nM, 1.6 nM and 0.5 nM, respectivelyLY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively.

YO-01027 (Dibenzazepine, DBZ) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM for APPL and Notch, respectively.Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM.

LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM and 0.082 nM for membrane- and cell-based γ-secretase.CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM.

TAK-901 is a novel inhibitor of Aurora A and Aurora B with IC50 of 21 nM and 15 nM, respectively.AMG 900 is a potent and highly selective pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 5 nM, 4 nM and 1 nM, respectively.

ZM 336372 is a potent and selective c-Raf inhibitor with IC50 of 70 nM.Nilvadipine (ARC029) is a potent calcium channel blocker with an IC50 of 0.03 nM.

JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM.PF-03814735 is a novel, potent and reversible inhibitor of both Aurora A and Aurora B with IC50 of 0.8 nM and 5 nM, respectively.

PH-797804 is a novel pyridinone inhibitor of p38α with IC50 of 26 nM.PF299804 is a potent, irreversible pan-ErbB inhibitor against ErbB1, ErbB2 and ErbB4 with IC50 of 6 nM, 45.7 nM and 73.7 nM, respectively.

AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM.SB 415286 is a potent GSK3α and GSK3β inhibitor with IC50 of 78 nM and ~78 nM, respectively.

Crenolanib (CP-868596) is a potent and selective inihibitor of PDGFRα with IC50 of 10 nM in PDGFRα over-expressed CHO cells.AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.

TG-101348 (SAR302503) is a selective inhibitor of JAK2 with IC50 of 3 nM.PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM.

PKI-402 is a potent dual PI3K/mTOR inhibitor targeting PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ and mTOR with IC50 of 2 nM, 7 nM, 16 nM, 14 nM, and 3 nM, respectively.GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B and Aurora C with IC50 of 3.5 nM and 6.5 nM, respectively.

PHA-767491 is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.PF-04691502 is an ATP-competitive, selective inhibitor of PI3K(α/β/δ/γ)/mTOR with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM, also inhibits Akt phosphorylation on T308/S473 with IC50 of 7.5 nM/3.8 nM.

CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM, respectively.CHIR-98014 is a potent and selective GSK-3 inhibitor for GSK-3ɑ and GSK-3β with IC50 of 0.65 nM and 0.58 nM, respectively.

AZ628 is a potent inhibitor for wild-type CRAF and BRAFV600E with IC50 of 29 nM and 34 nM, respectively. AMG 458 is a potent c-Met inhibitor of human c-Met and mouse c-Met with Ki of 1.2 nM or 2.0 nM.

Anacetrapib (MK0859) is a potent and selective rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, respectivelyNVP-BGT226 is a novel dual PI3K/mTOR inhibitor with IC50 of 1 nM.

GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM.PHA-848125 is a potent, ATP-competitive cyclin A/CDK2 inhibitor with IC50 of 45 nM.

ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM and also inhibits EGFR with IC50 of 4 μM. AT-406 is a potent IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase) inhibitor of XIAP, cIAP1, and cIAP2 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, respectively.

ARRY334543 is a selective and potent ErbB1 and ErbB2 inhibitor with IC50 of 7 nM and 2 nM, respectively.Wortmannin is a multi-target inhibitor of MLCK and PI3K with IC50 of 170 nM and 3 nM, also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM

PI3K/HDAC Inhibitor I is a dual PI3K and HDAC inhibitor for PI3Kɑ, HDAC1, HDAC2, HDAC3 and HDAC10 with IC50 of 19 nM, 1.7 nM, 5 nM, 1.8 nM and 2.8 nM, respectively.Canagliflozin is a highly potent and selective SGLT2 inhibitor for CHO-hSGLT2, CHO-rSGLT2 and CHO-mSGLT2 with IC50 of 4.4 nM, 3.7 nM and 2 nM, respectively.

NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.CH5424802 is a potent and selective ALK inhibitor with IC50 of 1.9 nM.

MK-2048 is an potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.

3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM and also blocks autophagosome formation.

Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively.

MK-5108 (VX-689) is a highly selective Aurora A inhibitor with IC50 of 0.064 nM.Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM.

SB705498 is a TRPV1 antagonist for hTRPV1 with pIC50 and pKi of 7.1 and 7.6 in HEK293 cells. MK-2461 is a potent inhibitor of c-Met, Ron, Flt1/3, PDGFRβ, Mer and FGFR1/2/3 with IC50 of 2.5 nM, 7 nM, 10 nM/22 nM, 22 nM, 24 nM and 65 nM/39 nM/50 nM, respectively.

Nocodazole inhibits Abl, Abl(E255K) and Abl(T315I) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM, respectively.CPI-613 inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase.

PF-5274857 is a potent and selective Smoothened (Smo) antagonist with IC50 and Ki of 5.8 nM and 4.6 nM, respectively.GW842166X is a potent and highly selective agonist of CB2 receptor.

M344 is a potent HDAC inhibitor with IC50 of 100 nM.RITA (NSC 652287) is a DNA damaging agent with IC50 of 2 nM and 20 nM in A498 and TK-10 cells, and also inhibits MDM2-p53 interaction by targeting to p53.

GW 4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM.AZD2014 is a novel dual mTORC1 and mTORC2 inhibitor with potential antineoplastic activity.

TAK-285 is a novel dual HER2 and EGFR inhibitor with IC50 of 17 nM and 23 nM, respectively.A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM.

INCB28060 is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM.CP-690550 is a novel inhibitor of JAK3 with IC50 of 1 nM.

Istradefylline (KW-6002) is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM.Sotrastaurin (AEB071) is a potent selective pan-PKC inhibitor and highly inhibits PKCθ with Ki of 0.22 nM.

Torcetrapib (CP-529414) is a CETP inhibitor with IC50 of 37 nM.VU0357121 is a novel allosteric modulator of mGlu5 with EC50 of 33 nM.

WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells .Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.

APO866 effectively inhibits NAMPT with IC50 of 0.09 nM.AZD4547 is a novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3 with IC50 of of 0.2 nM, 2.5 nM, and 1.8 nM, respectively.

BAY 80-6946 is a potent and highly selective reversible PI3K inhibitor for PI3Kα and PI3Kβ with IC50 of 0.469 nM and 3.72 nM, respectively.Galeterone (TOK-001, VN/124-1) is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively.

Sirtinol is a specific SIRT1 and SIRT2 inhibtor with IC50 of 131 μM and 38 μM, respectively.LY364947 is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM.

CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM.Dabrafenib (GSK2118436) is a potent ATP-competitive inhibitor of B-Raf, B-RafV600E and c-Raf with IC50 of 3.2 nM, 0.8 nM and 5.0 nM, respectively.

GDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 5 nM, 18 nM and 8 nM, respectively.MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM.

INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM.AT-101 is a BH3 mimetic known to be a potent inhibitor of antiapoptotic Bcl-2 family members.

Ciproxifan is a highly potent and selective H3-receptor antagonist with IC50 of 9.2 nM.BYL719 strongly and selectively inhibits PI3Kα.

AG879 inhibits both ErbB2 and Flk-1 with IC50 of 1 μM.Torin 2 is a highly potent and selective mTOR inhibitor with IC50 of 0.25 nM, and also exhibits potent cellular activity against ATM/ATR/DNA-PK with EC50 of 28 nM, 35 nM and 118 nM, respectively.

CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 μM.AM251 is a cannabinoid 1 receptor antagonist with IC50 of 8.9 μM.

NVP-TAE226, a potent dual FAK/IGF-1R, inhibiting FAK and IGF-1R with IC50 of 5.5 nM and 0.14 μM, respectively.RG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM.

Tideglusib (NP031112, NP-12) is a potent non ATP-competitive inhibitor of GSK3 with IC50 of 60 nM.TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM.

ML133 is a potent potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5).Desmethyl Erlotinib (CP-473420) is a free base of OSI-420, which is an active metabolite of Erlotinib which is an orally active EGFR inhibitor for human EGFR with IC50 of 2 nM.

Torin1 is a potent inhibitor of mTOR with IC50 of 2-10 nM.

JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human).

Epiandrosterone (3β-androsterone) is a steroid hormone with weak androgenic activity which acts as a L-type Ca2+ channel antagonist.ARN-509 is a selective androgen receptor inhibitor with IC50 of 16 nM.

SAR131675 is a VEGFR-3 inhibitor with IC50 of 20 nM.BI-D1870 is an ATP-competitive inhibitor of ribosomal S6 for RSK1, RSK2, RSK3 and RSK4 with IC50 of 31 nM, 24 nM, 18 nM and 15 nM, respectively.

Semaxanib (SU5416) is a potent and selective VEGFR (Flk-1/KDR) inhibitor with IC50 of 1.04 μM.Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.

SB-269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3.Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, respectively.

BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively.Carfilzomib (PR-171) is a proteasome inhibitor with IC50 less than 5 nM.

BML-190 is a selective CB2 inverse agonist with Ki of 435 nM.MRS2578 is a potent P2Y6 receptor with IC50 of 37 nM.

SB-271046 is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9.Dizocilpine is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.

StemRegenin 1 is an AhR inhibitor with IC50 of 127 nM.E7050 is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, respectively.

IEM 1754 dihydrobroMide is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.CTEP is a selective allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM.

VU 0364770 is a selective positive allosteric mGlu4 with EC50 of 1.1 μM.ML130 is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM.

IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NFκβ pathway.VUF10166 is a novel, potent and competitive antagonist to 5-HT3A with Ki of 0.04 nM.

U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with IC50 of 45.1 nM and 4.5 nM, respectively.WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM and also inhibits EGFR with IC50 of 4 nM.

Alogliptin(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of < 10 nM.TG 100713 is a PI3K inhibitor for PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.

T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM.GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM.

Camostat is a trypsin-like protease inhibitor, inhibiting matriptase and human neutrophil elastase with IC50 of 0.5 μM and 0.2 μM, respectively.Prucalopride is a selective, high affinity 5-HT receptor agonistfor 5-HT4a and 5-HT4b with Ki of 2.5 nM and 8 nM, respectively.

MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.L-NAME is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively.

IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.

PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively.GW 441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM.

SB-742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63.

SF 6847 is an inhibitor of EGFR with IC50 of 460 μM.ZM-323881 is a potent and selective inhibitor of VEGFR2 with IC50 < 2 nM.

ZM-306416 is a VEGFR inhibitor, inhibiting Src, VEGFR1 and Abl with IC50 of 0.33 μM, 0.33 μM and 1.3 μM, respectively.GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl, inhibiting the proliferation of the Bcr-Abl-expressing cells with IC50 of 138 nM.

Cobicistat (GS-9350) is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM.CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.

S-Ruxolitinib is a JAK family inhibitor for JAK1 and JAK2 with IC50 of 3.3 nM and 2.8 nM, respectively.Lumiracoxib (COX-189) is a novel, selective COX-2 inhibitor with Ki of 0.06 μM.

PF 477736 is a ChK inhibitor against ChK1, ChK2, VEGFR2, Yes and Fms with IC50 of 0.49 nM, 47 nM, 8 nM, 14 nM and 10 nM, respectively.JNJ-7777120 is a potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM.

Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively.

VU 0361737 is a selective positive allosteric modulator for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively.

Pirfenidone inhibits TGF-β bioactivity by affecting TGF-β2 mRNA expression and processing of pro-TGF-β in CCL-64 cells.

Go 6983 is a pan PKC inhibitor against PKCα, PKCβ, PKCγ, PKCδ, PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.

Bay 11-7082 inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM and inactivates the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13, UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex).Dapivirine is an nonnucleoside reverse transcriptase inhibitor for HIV reverse transcriptase with IC50 of 24 nM.

GW9662 is a selective PPAR antagonist, inhibiting PPARγ, PPARα and PPARδ with IC50 of 3.3 nM, 32 nM and 2 μM, respectively. HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.

IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM.Mozavaptan (OPC-31260) is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.

PF-4981517 is a potent and selective inhibitor of CYP3A4 (P450) with IC50 of 0.03 μM. Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with IC50 of 5 nM.

Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM.CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively.

LY2484595 is a potent and selective inhibitor of CETP with IC50 of 5.5 nM.TDZD-8 is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM.

Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells.TAK 715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM.

Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes.Rivaroxaban (Xarelto, BAY 59-7939) is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM, respectively.

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. Plerixafor 8HCl (DB06809, Mozobil, AMD3100) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.

Aspirin is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.

Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane.

Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.Lamotrigine is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, respectively.

PMSF (Phenylmethyl sulfonyl fluoride) is an irreversible serine/cysteine protease inhibitor.Piceatannol is a selective Syk inhibitor with IC50 of ~10 μM.

Niclosamide can inhibit DNA replication and inhibit STAT with IC50 of 0.7 μM.Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.

Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Vildagliptin (LAF-237) inhibits DPP−4 with IC50 of 2.3 nM.

Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively.Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.

Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.

Fosaprepitant (MK-0517, L-758,298) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.Rofecoxib (Vioxx) is a COX-2 inhibitor with IC50 of 18 nM.

Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively.Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM.

Otilonium bromide is an antimuscarinic.Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class.

Palonosetron HCl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 and 102 nM, respectively.Azelnidipine is a dihydropyridine calcium channel blocker.

Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa.

Paroxetine is an antidepressant drug of the SSRI type. Zaltoprofen is an inhibitor of Cox-1 and Cox-2 for treatment of arthritis.

Niflumic acid is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.

Ambroxol HCl is a potent inhibitor of the neuronal Na+ channels with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, respectively.

Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.Naloxone HCl is an opioid inverse agonist drug used to counter the effects of opiate overdose.

Piracetam is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.(R)-baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.

Dexmedetomidine is a sedative medication used by intensive care units and anesthetists.Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36.

Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.

Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9.Tripelennamine is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM.

Entacapone inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM.Estradiol is a synthetic ester used to treat menopausal symptoms and hormone deficiencies.

Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills.

Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.

Altrenogest is a progestogen structurally related to veterinary steroid trenbolone.Anagrelide is a drug used for the treatment of essential thrombocytosis.

Betahistine is a histamine H3 receptors inhibitor with IC50 of 1.9 μM.

Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.Flumequine is a synthetic chemotherapeutic antibiotic, inhibiting topoisomerase II with IC50 of 15 μM.

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.

Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.Ropinirole a selective dopamine D2 receptors inhibitor with IC50 of 29 nM.

Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.

Trifluoperazine is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM.Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 ¦ÌM

Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM.Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.

Moclobemide is MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.Betulinic acid is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.

Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist.Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

Sitagliptin phosphate (MK-0431) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

Doxycycline HCL is a tetracycline antibiotic that commonly used to treat a variety of infections and MMP inhibitor.Clinafloxacin (PD127391) is a fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumoniae.

Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.

Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.

Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.

Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.

Monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM.Hyoscyamine (Daturine) is an AChR inhibitor with IC50 of 7.5 nM.

Ouabain is a selective Na+, K+-ATPase inhibitor, binds to α2 subunit and α3 subunit with Ki of 41 nM and 15 nM, respectively.Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation.

Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM.Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.

Probenecid (Benemid) is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16.Procaine (Novocaine) HCl is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.

Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.Homatropine Bromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.

Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.Flavoxate is a muscarinic AChR antagonist with IC50 of 12.2 μM.

Dexamethasone is an interleukin receptor inhibitor and also suppresses COX-2. Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.

Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).

Doxapram HCl inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.

Dibucaine (Cinchocaine) HCl is a local anesthetics.Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.

Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity.Valdecoxib is a potent and selective inhibitor of COX-2 with IC50 of 5 nM.

Nabumetone is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX.Sertraline HCl is a 5-HT antagonist with Ki of 13 nM.

Spironolactone is a potent antagonist of the androgen receptor with IC50 of 77 nM.Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.

Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.Vitamin D3 (Cholecalciferol) is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM.

Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.

Dequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM.Hexamethonium Bromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.

Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-?oB inhibition and free radical scavenging.

Sodium nitrite is a myeloperoxidase inhibitor with IC50 of 1.3 μM.Zinc pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.

Propranolol HCl is a competitive non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM.Mefenamic acid is a competitive inhibitor of COX-1 and COX-2.

Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner with IC50 of 4.5 μM.

Sulfacetamide Sodium is an anti-biotic.Lorcaserin HCl is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM.

Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.

Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively. Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.

Timolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.

Sodium Phenylbutyrate is a transcriptional regulators that act by altering chromatin structure via the modulation of HDAC activity.

Vitamin D2 is a selective inhibitors of mammalian DNA polymerase A (pol A) with IC50 of 123 mM.

Guanabenz (WY-8678) Acetate is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively.

Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist, also inhibits CYP2C9 and 4-hydroxylation with IC50 of 10.5 μM and 8.2 μM respectively.

Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.

Pefloxacin Mesylate Dihydrate is the third generation of fluoroquinolone class of antibacterials, which inhibits Topoisomerase II activity and DNA replication.

Terbutaline Sulfate is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.

DeoxyArbutin is a reversible tyrosinase inhibitor, inhibiting tyrosinase activity with IC50 of 50 nM.Tofacitinib citrate (CP-690550) is a potent JAK3 inhibitor with IC50 of 1 nM.

FTY720 (Fingolimod, Gilenya) is a S1P antagonist with IC50 of 0.033 nM.LY404039 is a potent agonist of recombinant human mGlu2, mGlu3 receptors and rat neurons expressing native mGlu2/3 receptors with Ki of 149 nM, 92 nM and 88 nM, respectively.

PTC124 (Ataluren) is a potent nonsense mutation inhibitor with EC50 of ~0.1 μM.VX-702 is a highly selective inhibitor of p38 MAPKα with IC50 of 4-20 nM.

PP2 is Src kinase inhibitor, potently inhibits GST-Src activity with IC50 of 100 nM.Stattic inhibits STAT3 with IC50 of 5.1 μM.

IPI-145 (INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM.

AZD2461 is a poor P-glycoprotein substrate with lower affinity for Pgp than does olaparib.

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells.Oprozomib (ONX 0912) selectively inhibits CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM.

VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface.GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3/UTX with IC50 of 60 nM.

(+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM.

Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively.KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling.

(-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases with IC50 from 0.5-5 μM.Zebularine is an inhibitor of cytidine deaminase and also inhibit DNA methylation.

AMG 517 is a potent and selective transient receptor potential vanilloid-1 (TRPV1) antagonist with IC50 of <10 nM. Tenovin-1 protects against MDM2-mediated p53 degradation, which invloves ubiquitination, and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2.

Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM.GSK2636771 is a potent, orally bioavailable, PI3Kβ-selective inhibitor.

PQ 401 is an IGF-1R inhibitor with IC50 of <1 μM.ZM39923 is an JAK inhibitor for JAK1, JAK3, EFGR and TGM2 with IC50 of 4.4 μM, 7.1 μM, 5.6 μM and 10 nM, respectively.

SMI-4a is a potent inhibitor of Pim1 with IC50 of 17 nM.BIX01294 is an inhitor of G9a histone methyltransferase with IC50 of 2.7 μM.

VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively.AG 18 inhibits EGFR with IC50 of 35 μM.

PRX-08066 is a selective 5-HT2B antagonist with IC50 of 3.4 nM.CP-945598 HCl is a potent and selective cannabinoid type 1 receptor antagonist with Ki of 0.7 nM.

GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32.CEP-32496 is a RAF inhibitor for BRAF(V600E), BRAF(WT), c-Raf, Abl-1 and CSF-1R with IC50 of 14 nM, 36 nM, 39 nM, 3 nM and 9 nM, respectively.

TAK-438 is a novel potassium-competitive acid blocker (P-CAB) type antisecretory agent that reversibly inhibits gastric H+, K+-ATPase with IC50 of 19 nM at pH 6.5.AZD5363 is a potent Akt inhibitor for Akt1, Akt2 and Akt3 with IC50 of 3 nM, 8 nM and 8 nM, respectively.

GW0742 is a potent and highly selective PPARβ/δ agonist, binding to hPPARδ with IC50 of 1 nM.Lu-AA21004 is an oral multimodal serotonergic agent, inhibits 5-HT(1A), 5-HT(1B), 5-HT(3A), 5-HT(7) and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.

Empagliflozin (BI-10773) is a potent and selective SGLT2 inhibitor with IC50 of 3.1 nM.TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.

Tyrphostin AG 1296 (AG 1296) is an inhibitor of PDGFR, FGFR and c-Kit with IC50 of < 1 μM, 12.3 μM and 1.8 μM, respectively.GSK3787 is as a potent and selective antagonist of PPARδ with pIC50 of 6.6.

Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM.WY 14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with ED50 of 1.5 μM.

Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of about 50 μM.

Embelin, from the Japanese Ardisia herb, is a fairly potent, nonpeptidic, cell-permeable inhibitor of XIAP and efficiently overcomes the protective effect of XIAP XLALP to apoptosis.

NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of L-glutamate.

Apremilast (CC-10004) is a potent PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively.

Butein, a plant polyphenol isolated from Rhus verniciflua, inhibits EGFR tyrosine phosphorylation with IC50 of 8 μM.

Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.UPF 1069 is a selective PARP2 inhibitor with IC50 of 0.3 μM.

GDC-0349, is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM.GW2580 is a selective inhibitor of human c-FMS with IC50 of 30 nM.

Scriptaid is an inhibitor of histone deacetylase.ABT-199 is a Bcl-2-selective inhibitor with Ki of < 0.010 nM.

Macitentana (Actelion-1, ACT-064992) is an orally active, non-peptide dual endothelin (ET)A/B receptor antagonist with IC50 of 0.5 nM/391 nM.

ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively.

Linifanib (ABT-869) is a novel, potent ATP-competitive RTK inhibitor for KDR, CSF-1R, Flt-1, Flt-3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM, 3 nM, and 66 nM respectively.ABT-888 (Veliparib, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively.

Axitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively.

BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM.BIBF1120 (Vargatef) is a potent inhibitor of VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.

BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.

Cediranib (AZD2171) is a highly potent VEGFR2 inhibitor with IC50 of 0.5 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM.

Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.

Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.

Lapatinib Ditosylate (GW572016, GW2016, Tykerb, Tyverb) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.

Pazopanib Hydrochloride (GW786034, Votrient, Armala) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively.

PI-103 is a potent, ATP-competitive PI3K inhibitor of DNA-PK, p110α, mTORC1, PI3KC2β, p110δ, mTORC2, p110β, and p110γ with IC50 of 2 nM, 8 nM, 20 nM, 26 nM, 48 nM, 83 nM, 88 nM and 150 nM, respectively.

Sorafenib Tosylate (Bay 43-9006, Nexavar) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.

Sunitinib Malate (Sutent, SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.

Tandutinib (MLN518, CT53518) is an ATP-competitive and highly selective inhibitor of Flt3, PDGFRβ and c-Kit with IC50 of 0.22 μM, 0.20 μM and 0.17 μM, respectively.

VX-680 (MK-0457, Tozasertib) is a pan-Aurora inhibitor of Aurora A, Aurora B and Aurora C with Kiapp of 0.6 nM, 18 nM and 4.6 nM, respectively.

Elesclomol (STA-4783) is a novel potent oxidative stress inducer that illicits pro-apoptosis events among tumor cells..

Enzastaurin (LY317615) is a potent PKC inhibitor for PKCβ, PKCα, PKCγ and PKCε with IC50 of 6 nM, 39 nM, 83 nM and 110 nM, respectively.

BMS-599626 (AC480) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, respectively.

Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1 and PARP2 with IC50 of 5 nM and 1 nM, respectively. Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM.

Masitinib is a novel tyrosine kinases inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, resectively.

Dasatinib (BMS-354825, Sprycel) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of ＜1 nM, 0.5 nM and 79 nM, respectively.

GDC-0941 is a potent inhibitor of PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ with IC50 of 3 nM, 33 nM, 3 nM and 75 nM, respectively.

NVP-AUY922 (VER-52296) is a highly potent HSP90 inhibitor for HSP90α and HSP90β with IC50 of 13 nM and 21 nM, respectively.

SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM and blocks PKB phosphorylation with IC50 of 3-5 μM. SB 202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38α and p38β with IC50 of 50 nM and 100 nM, respectively.

MK-2206 2HCl is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC50 of 8 nM, 12 nM and 65 nM, respectively.

GDC-0449 (Vismodegib, HhAntag691) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM.

Brivanib is an ATP-competitive inhibitor against human VEGFR2 and FGFR with IC50 of 25 nM and 148 nM, respectively.

PCI-24781 (CRA-024781) is a novel broad spectrum HDAC inhibitor targeting HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki of 7 nM, 19 nM, 8.2 nM, 17 nM, 280 nM, 24 nM, respectively.

JNJ-26481585 (Quisinostat) is an HDAC inhibitor for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11 with IC50 of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM and 0.37 nM, respectively.BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.

Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.U0126-EtOH is a highly selective inhibitor of MEK1 and MEK2 with IC50 of 0.07 μM and 0.06 μM, respectively.

ZM-447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively.

LY294002 is a PI3K inhibitor for p110α, p110δ and p110β with IC50 of 0.5 μM, 0.57 μM and 0.97 μM, and also blocks autophagosome formation.

Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.

LY315920 (Varespladib) is a potent and selective secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM.

XL880 (GSK1363089, EXEL-2880) is an ATP-competitive inhibitor of MET and KDR with IC50 of 0.4 nM and 0.9 nM, respectively.

GSK690693 is a pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 2 nM, 13 nM, and 9 nM, respectively.

Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of human and rabbit cathepsin K with IC50 of 0.2 nM and 1 nM , respectively.PD 0332991 is a highly selective inhibitor of CDK4/cyclin D1 and CDK6/cyclin D2 with IC50 of 11 nM and 16 nM, respectively.

Triciribine (TCN, API-2) is a DNA synthesis inhibitor and also inhibits Akt and HIV-1 with IC50 of 130 nM and 20 nM, respectively.XL147 (SAR245408) is a selective and reversible class I PI3K inhibitor for wild type and mutant p110α with IC50 of 40 nM and 40 nM, respectively.

XL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.

MGCD0103 (Mocetinostat) is a potent HDAC inhibitor for HDAC1, HDAC2 and HDAC3 with IC50 of 0.15 μM, 0.29 μM and 1.66 μM, respectively.

YM155 is a potent IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase) inhibitor for survivin with IC50 of 0.54 nM.INO-1001 is a potent inhibitor of PARP with IC50 of 50 nM and a mediator of oxidant-induced myocyte dysfunction during reperfusion.

AT9283 is a potent pan-Aurora inhibitor for Aurora A, Aurora B, JAK3, JAK2 and Abl with IC50 of 3 nM, 3 nM, 1.1 nM, 1.2 nM and 4 nM, respectively.

Pemetrexed disodium (Alimta) is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.BMS-582664 is an oral VEGFR/FGFR inhibitor for VEGFR2, Flk1, VEGFR1 and FGFR1 with IC50 of 25 nM, 89 nM, 380 nM and 148 nM, respectively.

AG-490 (Tyrphostin B42) is an inhibitor of EGFR, ErbB2 and JAK2 with IC50 of 0.1 μM, 13.5 μM, and ~10 μM, respectively.Ivacaftor (VX-770, Kalydeco) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.

SNS-032 is a novel, potent and selective CDK inhibitor of CDK2, CDK7 and CDK9 with IC50 of 38 nM, 62 nM and 4 nM, respectively. Cyclopamine is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM.

Docetaxel, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules.

Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.Paclitaxel (Taxol, Onxol, Nov-Onxol) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

PLX-4720 is a potent and selective inhibitor of B-RafV600E and c-Raf-1Y340D/Y341D with IC50 of 13 nM and 6.7 nM, respectively.Roscovitine (Seliciclib, CYC202, R-roscovitine) is a potent and selective CDK inhibitor for Cdc2/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p53 with IC50 of 0.65 μM, 0.7 μM, 0.7 μM and 0.16 μM, respectively.

SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3.4 nM, respectively.

Capecitabine is a tumor-selective fluoropyrimidine carbamate which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU.MK-8245 is an inhibitor of stearoyl-CoA desaturase (SCD) which targets the liver with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1.

TRAM-34 is a selective and potent inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1) with Kd of 20 nM.

E7080 (Lenvatinib) is a multi-target inhibitor of VEGFR2 and VEGFR3 with IC50 of 4 nM and 5.2 nM, respectively.

Cisplatin is an inorganic and water-soluble platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts.

CP-724,714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM and also inhibits EGFR with IC50 of 6.4 μM.

WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM, respectively.

WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFRL858R and EGFRL858R/T790M with IC50 of 2 nM and 8 nM, respectively. Ostarine (GTx-024, MK-2866, Enobosarm, S-22) is a selective androgen receptor modulator (SARM) with Ki of 3.8 nM.

Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.

XAV-939 is a selective Wnt β-catenin-mediated transcription inhibitor for TNKS1 and TNKS2 with IC50 of 11 nM and 4 nM, respectively.ENMD-2076 is a selective inhibitor of Aurora A and Aurora B with IC50 of 14 nM and 350 nM and also inhibits Flt3, Flt4 and VEGFR2 with IC50 of 1.86 nM/15.9 nM and 58.2 nM, respectively.

Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM.

Valproic acid sodium salt (Sodium valproate) is a HDAC inhibitor with IC50 of 0.4 mM and also inhibits GABA-transaminase or succinic

PIK-90 is a potent and cell permeable inhibitor of p110α, p110β, p110γ and p110δ with IC50 of 11 nM, 350 nM, 18 nM and 58 nM, respectively.

Bicalutamide (Casodex, Cosudex, Calutide, Kalumid) is an androgen receptor (AR) antagonist with IC50 of 0.16 μM.

Raltitrexed (Tomudex) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth.

CUDC-101 is a potent multi-target inhibitor targeting HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, respectively.TAK-700 (Orteronel) is a potent and highly selective rat and human 17,20-lyase inhibitor with IC50 of 54 nM and 38 nM, respectively.

Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.

Irinotecan (Camptosar, Campto, CPT-11) is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.Cladribine (Leustatin, Litak, 2CDA) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.

Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively.

PIK-75 is a selective and competitive inhibitor of p110α with IC50 of 5.8 nM and also potently inhibits DNA-PK with IC50 of 2 nM.

Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.Adrucil (Fluorouracil) is an DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS).

Abitrexate (Methotrexate) is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.

Nelarabine (Arranon, 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.Bleomycin sulfate (Blenoxane) is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.

OSI-930 is a potent inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck with IC50 of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM, respectively.

Epirubicin HCl, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase.

Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity.

KU-0063794 is a potent and highly specific mTOR inhibitor for both mTORC1 and mTORC2 with IC50 ~10 nM.Raloxifene is estrogen antagonists, inhibits human cytosolic aldehyde oxidase-catalyzed phthalazine oxidation activity with IC50 of 5.7 nM.

Idarubicin HCl (Idamycin, Zavedos, 4-demethoxydaunorubicin) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.

Topotecan (Hycamtin, NSC 609699) is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM, respectively.

Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.MP-470 (Amuvatinib) is a potent and multi-targeted inhibitor of c-KitD816H, PDGFαV561D and Flt3D835Y with IC50 of 10 nM, 40 nM and 81 nM, respectively.

JNJ-7706621 is a potent and multi-target inhibitor for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, Aurora A and Aurora B with IC50 of 9 nM, 4 nM, 3 nM, 11 nM and 15 nM, respectively.

Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.Thalidomide inhibits an E3 ubiquitin ligase， which is a CRBN-DDB1-Cul4A complex.

AV-951 (Tivozanib, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM and also inhibits PDGFR and c-Kit with IC50 of 1.72 nM and 1.63 nM, respectively.

Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.

AMG-073 HCl (Cinacalcet hydrochloride) represents a new class of compounds for the treatment of hyperparathyroidism.

BMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectively.PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM.

PLX4032 (Vemurafenib, RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM.

BX795 is a potent and specific TBK1, IKKε and PDK-1 inhibitor with IC50 of 6 nM, 41 nM and 111 nM, respectively.

Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.

Asenapine ihibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.

Camptothecin (Camptohecine, 20-(S)-Camptothecin, CPT, NSC100880) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM.

Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.

Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake.

Floxuridine (Fludara) is a prodrugs of floxuridine and an oncology agent with an GI50 of 5.1 μM for the inhibition of MDCK/PEPT1.

Mercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

A potent nitrogen-containing bisphosphonates.It inhibited proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 μM.Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.

Costunolide inhibits FPTase with IC50 of 20 μM and also inhibits telomerase with IC50 of 90 μM and 65 μM in MCF-7 and MDA-MB-231 cells.

Flupirtine maleate is the salt form of Flupirtine, which is a non-opioid, centrally acting analgesia, muscle relaxation and neuroprotection.

Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.

TG100-115 is a potent and dual selective inhibitor for PI3Kγ and PI3Kδ with IC50 of 83 nM and 235 nM, respectively.

Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively.

Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

GSK1059615 is a novel and dual inhibitor of PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR with IC50 of 0.4 nM, 0.6 nM, 2 nM, 5 nM and 12 nM, respectively.MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met, VEGFR1, VEGFR2, VEGFR3, Ron, and Tie2 with IC50 of 1 nM, 3 nM, 3 nM, 4 nM, 2 nM and 7 nM, respectively.

Rigosertib (Estybon, Novonex, ON-01910) is a non-ATP-competitive inhibitor of PLK1 (Polo-like kinase 1) with IC50 of 9 nM.Ki8751 is a potent and selective inhibitor of VEGFR2, PDGFRα and c-Kit with IC50 of 0.9 nM, 67 nM and 40 nM, respectively.

INCB018424 is a JAK family inhibitor for JAK1, JAK2 and JAK3 with IC50 of 2.7 nM, 4.5 nM and 322 nM, respectively.It was developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.

Mizoribine (Bredinin) is an imidazole nucleoside and an immunosuppressive agent with an IC50 of approximately 100 μM.

Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.

Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.

Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects.

Droxinostat (CMH, 5809354) is a selective inhibitor of HDAC3, HDAC6 and HDAC8 with IC50 of 16.9 μM, 2.47μM and 1.46 μM, respectively.

Sumatriptan succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.Tianeptine is a selective serotonin reuptake enhancer (SSRE) compound used for treating major depressive episodes.

Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.

Voriconazole (VFEND) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections.

Zileuton (ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation.

Ispinesib (SB-715992, CK0238273) is a potent, specific and reversible inhibitor of KSP (HsEg5) with Ki of 1.7 nM.

Tipifarnib (Zarnestra, R115777) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM.PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, repectively.

Cilomilast (SB-207499) is a potent LPDE4 and HPDE4 inhibitor with IC50 of 100 nM and 120 nM, respectively.

SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM, respectively.

TSU-68 (SU6668, Orantinib) is a potent inhibitor of Flk-1/KDR, FGFR1 and PDGFRβ with Ki of 2.1 μM, 1.2 μM, and 8 nM, respectively.Safinamide Mesylate is mesylate salt of Safinamide, which selectively and reversibly inhibits MAO-B with IC50 of 0.45 μM.

LY335979 (Zosuquidar) is a potent modulator of P-glycoprotein-mediated multidrug resistance with Ki of 60 nM.

AEE788 is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM and also inhibits VEGFR2 and Flt with IC50 of 77 nM and 59 nM, respectively.

PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM, respectively.

AP24534 is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively.

Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively.

Irbesartan (Avapro, SR-47436, BMS-186295) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.

CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively.

CHR-2797 is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively.XL765 is a dual inhibitor of mTOR/PI3k for mTOR, p110α, p110β, p110γ and p110δ with IC50 of 157 nM, 39 nM, 113 nM, 9 nM and 43 nM, respectively.

AT7519 is a novel multi-CDK inhibitor for CDK1/cyclin B, CDK2/Cyclin A, CDK3/Cyclin E, CDK4/Cyclin D1, CDK5/p35 and CDK6/Cyclin D3 with IC50 of 210 nM, 47 nM, 360 nM, 100 nM, 13 nM and 170 nM, respectively.

AC220 (Quizartinib) is a potent and selective inhibitor of Flt3ITD and Fltwt with IC50 of 1.1 nM and 4.2 nM, respectively.LY2811376 is a non-peptidic BACE1 inhibitor with IC50 of 239 nM/249 nM and also decreases the Aβ secretion with EC50 of ~300 nM.

Hesperadin inhibits Aurora B and T. brucei Aurora kinase-1 (TbAUK1) with IC50 of 250 nM and 40 nM, respectively.

DMXAA (ASA404) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM, respectively.

SB-408124 (Tocris-1963) is a non-peptide antagonist for OX1 with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively.

KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM and also inhibits PDGFRα/β with IC50 of 965 nM/9850 nM.

AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and S6K with IC50 of 32 nM/17 n/47 nM and 85 nM, respectively.BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively.

Fasudil is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively.

PD 0332991 (Palbociclib) Isethionate is the isethionate of PD 0332991, a highly specific inhibitor of CDK4 and CDK6 with IC50 of 11 nM and 16 nM, respectively.

H 89 2HCl is a mutiple-targeted inhibitor for S6K1, MSK1, PKA, ROCKII, PKBα and MAPKAP-K1b with IC50 of 80 nM, 120 nM, 135 nM, 270 nM, 2600 nM and 2800 nM, respectively.

Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.

Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, respectively. Semagacestat also inhibits Notch signaling with IC50 of 14.1 nM.Olmesartan medoxomil (Benicar) is a compound which is hydrolyzed to olmesartan that is a selective AT1 subtype angiotensin II receptor antagonist.

Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.

Acetylcysteine is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose.

Naproxen (Aleve, Anaprox) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.Nitazoxanide(Alinia, Annita) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)

Ibuprofen (Advil, Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.

Ketoprofen (Actron) is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.

Ketorolac (Ketorolac tromethamine, Toradol) is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.Cytarabine (Cytosine arabinoside, AraC) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells.

Aminophylline(Phyllocontin, Truphylline) is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.

Divalproex sodium consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form.

Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.

Telmisartan (Micardis) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.

Nevirapine(Viramune) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.

Nimodipine(Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy.Nisoldipine (Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.

Quetiapine fumarate(Seroquel) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.

Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.Thioguanine is a purine antimetabolite widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.

Toremifene Citrate(Fareston, Acapodene) is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body.Azacitidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases.

Bacitracin zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.

Acadesine results in accumulation of ZMP, which mimics both activating effects of AMP on AMPK and AMPKK.The chemical compound acetylcholine (ACh) is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.

Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM.

Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.Butoconazole nitrate is an anti-fungal agent for IL-2, TNFα, IFN and GM-CSF with IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively.

Cimetidine(Tagamet), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.

Tropisetron hydrochloride is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.

Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor- and M3 receptor-mediated currents with IC50 of 11.4 ¦ÌM and 6.0 ¦ÌM, respectively.

Irsogladine is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.

Enalapril maleate (Vasotec), the active metabolite of enalapril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II.Metformin hydrochloride(Glucophage) is a biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification.

Nefiracetam (Translon) is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions.

Adenine sulfate is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.Adenine hydrochloride is a hydrochloride salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.

Procarbazine hydrochloride (Matulane) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound used as an antineoplastic agent.

Elvitegravir (EVG, JTK-303/GS-9137) is a HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.

Maraviroc (Selzentry, UK-427857, Celsentri) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM, respectively.Raltegravir (MK-0518, Isentress) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectivly.

BMS265246 is a potent and selective CDK inhibitor for CDK1/cyclin B and CDK2/cyclin E with IC50 of 6 nM and 9 nM, respectively.Suplatast tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.


Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Tropicamide is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.

Amiodarone HCl is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM.

Formoterol hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist to β2 and β1 receptors with pKd of 8.12 and 5.58, respectively.

Ketotifen fumarate (Zaditor) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.Urapidil hydrochloride is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.

Candesartan cilexetil (Atacand) is a specific nonpeptide Ang II receptor (ATR) antagonist and the prodrug of candesartan which is an ATR antagonist with an IC50 of 15 μg/kg

Moexipril hydrochloride is a potent orally active non-sulfhydryl angiotensin converting enzyme inhibitor (ACE) with IC50 of 0.041 ¦ÌM, which is used for the treatment of hypertension and congestive heart failure.

Gabexate is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation.

Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14.5 μM.

Flunarizine dihydrochloride is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.Rebamipide is a cholecystokinin type 1 (CCK1) receptor inhibitor for inhibiting [125I]BH-CCK-8S with IC50 of 37.7 μM.

Memantine hydrochloride (Namenda) is a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively.

Cyproheptadine hydrochloride (Periactin) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM.

Pioglitazone hydrochloride (Actos) is a hydrochloride salt form of pioglitazone which is a cytochrome P450 (CYP)2C8 and CYP3A4 enzymes inhibitor for CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively.

Strontium ranelate (Protelos) is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.

Orphenadrine citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.

Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent).

Ozagrel hydrochloride is a selective thromboxane A2 synthetase enzyme inhibitors with IC50 of 11 nM, used as antiasthmatic agent.Mitiglinide is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.

Rosiglitazone is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells. Lisinopril is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.

Atorvastatin (Lipitor) is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol.Famotidine is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.

Cleviprex (Clevidipine) is a dihydropyridine calcium channel blocker use as agent for the reduction of blood pressure.

Cilazapril is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.

Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.

Ivabradine, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.Rivastigmine, a cholinesterase inhibitor with IC50 of 5.5 μM, ues as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.

Dexmedetomidine is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.

Detomidine produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.Fosinopril sodium (Monopril) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

Almotriptan malate (Axert) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.Ambrisentan, a highly selective antagonist of the endothelin-1 type A receptor with IC50 of 18 nM, is indicated for the treatment of pulmonary arterial hypertension (PAH).

Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.Temocapril HCl is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.

Naltrexone is an opioid receptor antagonist with IC50 of 8 nM used primarily in the management of alcohol dependence and opioid dependence.

Lapatinib, used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.

Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM.Atropine sulfate monohydrate is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM.

Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM, respectively.LDE225 (NVP-LDE225) is a smoothened antagonist with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.

Tebipenem pivoxil(L-084) is a novel oral carbapenem antibiotic with an IC50 of 100 μg/ml for human CYP isoformsPF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki of 20 nM and IC50 of 160 nM.

MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM, respectively.

MLN9708 is a selective inhibitor of chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM. SB 743921 is a KSP inhibitor with IC50 of 0.2 nM, 0.07 nM, 1.7 nM, 0.06 nM and 14.4 nM in SKOV3, Colo205, MV522, MX1 and P388 cell lines, respectively.

BGJ398 (NVP-BGJ398) is a potent and selective inhibitor of FGFR1, FGFR2 and FGFR3 with IC50 of 0.9 nM, 1.4 nM and 1 nM, respectively.

AZD8931 is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM, respectively.

SGI-1776 is a novel ATP competitive inhibitor to Pim1, Pim2 and Pim3 with IC50 of 7 nM, 363 nM and 69 nM, respectively.

BMS794833 is a potent ATP competitive inhibitor of Met and VEGFR2 with IC50 of 1.7 nM and 15 nM, respectively.

NVP-BHG712 is a specific inhibitor of c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM and also inhibits EphB4 and VEGFR2 with ED50 of 25 nM and 4.2 μM, respectively.OSI-420 is an active metabolite of Erlotinib which is an orally active EGFR inhibitor for inhibition of human EGFR and EGFR autophosphorylation with IC50 of 2 nM and 20 nM, respectively.

PIK-293 is a PI3-K inhibitor for p110α, p110β, p110δ and p110γ with IC50 of 100 μM, 25 μM, 0.24 μM and 10 μM, respectively.

Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.

Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.

Flunixin meglumine is a potent inhibitor of the enzyme cyclooxygenase used as analgesic agent with anti-inflammatory and antipyretic activity. Vinpocetine is a selectively inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease.

Blonanserin is a novel atypical antipsychotic agent with potent dopamine D2 (Ki, 14.8 nM) and serotonin 5-HT2(Ki, 3.98 nM) receptors antagonist properties.

Cisatracurium besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.

Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.

DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.

Tosyl-L-Arginine Methyl Ester (TAME) is an APC inhibitor and also inhibits an E3 ubiquitin ligase called "anaphase-promoting complex/cyclosome (APC/C)".

Eltrombopag (SB-497115-GR, Promacta, Revolade) is a small molecule agonist of the c-mpl (TpoR) receptor with an IC50 of 0.69 μM for the inhibition of hERG K+ channel tail current.

Telatinib (BAY 57-9352) is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRβ with IC50 of 6 nM/4 nM, 1 nM and 15 nM, respectively.

Ketanserin (Vulketan Gel) is specific 5-HT2A serotonin receptor antagonist with a Ki of 2.5 nM for rat and human 5-HT2A.Esomeprazole sodium (Nexium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.

Palomid 529 (P529) is a PI3K/Akt/mTOR inhibitor for VEGF-A and bFGF with IC50 of 10 nM and 30 nM, respectively.

Fesoterodine fumarate (Toviaz) is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.WP1130 (degrasyn) is a selective deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor and also inhibits Bcr/Abl with IC50 of 1.8 μM.

Abiraterone acetate (CB7630, CB 7630, CB-7630) is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM.BKM120 is a selective PI3K inhibitor of p110α, p110β, p110δ and p110γ with IC50 of 52-99 nM, 166 nM, 116 nM and 262 nM, respectively.

(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM.

Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.

Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69.Asiatic acid is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.

Honokiol is a biphyl neolignan present in the cones, bark, and leaves of Magnolia grandifloris that displays antiangiogenic, antiinflammatory, and antitumor properties due to the inhibitory effect on the PI3K/Akt pathway.

Icariin is a flavonol and PDE5 inhibitor with IC50 of 1.0, 0.75, and 1.1 μM for PDE5A1, A2, and A3, respectively.

Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.Neohesperidin is an antioxidant agent with an IC50 of 22.31 μg/ml in the 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay.

Parthenolide ((-)-Parthenolide) is a sesquiterpene lactone which occurs naturally in the plant feverfew(Tanacetum parthenium) and also promotes the ubiquitination of MDM2 and activates p53 cellular functions.

5-Hydroxytryptophan(5-HTP) is decarboxylated to serotonin (5-hydroxytryptamine or 5-HT) by the enzyme aromatic-L-amino-acid decarboxylase with the help of Vitamin B6.

Naringenin is a flavonoid that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator.

Salidroside (Rhodioloside; Rhodosin) is a glucoside compound with an IC50 of 4.99 ± 0.23 μg/mL for the proliferation of SACC-2 cells.Sodium Danshensu is a mono sodium of danshensu which is a compound isolated from Salvia miltiorrhiza Bge.

Astragaloside A is a pure small molecular compound isolated from Radix Astragali and is commonly used in the treatment of degenerative bone diseases such as osteoporosis. 20-Hydroxyecdysone (Ecdysterone, 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods.

10-Hydroxycamptothecin (10-HCPT, 10-hydroxy-CPT, OHCPT, NSC107124) is a DNA topoisomerase I inhibitor with potent anti-tumor activity.

Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

Amantadine hydrochloride(Symmetrel) is used to treat or prevent infections of the respiratory tract caused by a certain virus.

Amfebutamone (Bupropion) is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4μM for the reuptake of dopamine and norepinephrine, respectivelyBenserazide is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.

Chlorpromazine (Sonazine) is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for nward-rectifying K+ currents and time-independent outward currents

Clozapine (Clozaril) is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.Pramipexole (Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.

Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.

Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.

Manidipine (Manyper) is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM.Manidipine HCl is a HCl salt form of Manidipine which is a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.

Milrinone(Primacor) is a a potent and selective phosphodiesterase 3 inhibitor with an IC50 of 0.42 μM for the inhibition of FIII PDE

Nateglinide(Starlix) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.

Olopatadine hydrochloride(Opatanol) is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine

Propafenone(Rytmonorm) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.

Vardenafil Hydrochloride Trihydrate (Vivanza) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.

Maprotiline hydrochloride (Deprilept, Ludiomil, Psymion) is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.

Naphazoline hydrochloride (Naphcon) is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.

Phenytoin (Lepitoin; NSC 8722; Phenytek; Phenytoine; Sodanton; Zentropi) is an inactive voltage-gated sodium channel stabilizer.

Alizarin strongly inhibits P450 isoform CYP1A1, CYP1A2 and CYP1B1 with IC50 of 6.2 μM, 10.0 μM and 2.7 μM, respectively.Dopamine hydrochloride (Inotropin) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.

Ritodrine hydrochloride (DU 21220; Miolene; NSC 291565; Pre-Par) is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.

Clomipramine hydrochloride (Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. Phenformin hydrochloride is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class.

Tiotropium Bromide hydrate is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.

Tolterodine tartrate (Detrol LA) is a tartrate salt of tolterodine that is a competitive muscarinic receptor antagonist.

Rosiglitazone (Avandia) is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively.

Hydralazine hydrochloride is a hydrochloride salt of hydralazine (Apresoline) that is a direct-acting smooth muscle relaxant with an IC50 of 1.9 mM.

Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.

Tetracaine hydrochloride (Pontocaine) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.

Quinapril hydrochloride (Accupril) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.

Tolvaptan (OPC-41061) is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28¦ÌM for the inhibition of AVP-induced platelet aggregation.Gliclazide (Diamicron) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 ¡À 30 nM

Acemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.

Mifepristone (Mifeprex, RU-486, RU-38486, Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively.

Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.

Scopine HCl is the hydrochloride of Scopine, which is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.

Isoprenaline is a non-selective β-adrenoceptor, inhibits the 3H-inositol phosphate accumulation with IC50 of 0.08 μM.

Trazodone is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

PP-121 is a multi-target inhibitor of PDGFR, Hck, mTOR, VEGFR2, Src and Abl with IC50 of 2 nM, 8 nM, 10 nM, 12 nM, 14 nM and 18 nM, respectively, and also inhibits DNA-PK with IC50 of 60 nM.OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively.

PKI-587 is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM, respectively.

PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM in α7*-expressing SH-EP1 cells.GW3965 is a potent, selective LXR agonist, which exhibits its potency in the LXRα/SRC1 LiSA and LXRα-GAL4 with EC50 of 125 nM and 190 nM, respectively.

BMS-806 (BMS 378806) selectively inhibitis the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.

DCC-2036 is a conformational control inhibitor of Abl1 and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, respectively.

NU7441 is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM.SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, respectively.

PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and also inhibits Her-2 degradation with IC50 of 37 nM.GSK2126458 is a highly selective and potent inhibitor of p110α, p110β, p110γ, p110δ, mTORC1 and mTORC2 with Ki of 0.019 nM, 0.13 nM, 0.024 nM, 0.06 nM, 0.18 nM and 0.3 nM, respectively.

MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM in human SH-SY5Y cells.

PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively. GSK1120212 (JTP-74057, trametinib) is a highly specific and potent MEK1 and MEK2 inhibitor with IC50 of 0.92 nM and 1.8 nM, respectively.

NSC-207895 suppresses MDMX with IC50 of 2.5 ¦ÌM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulate MDM2, an E3 ligaseFlavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM, and CDK7 with IC50 of 300 nM.

BMY 7378 is a multiple inhibitors of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively.

GDC-0980 (RG7422) is a potent, selective inhibitor of PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ with IC50 of 5 nM, 27 nM, 7 nM, and 14 nM, and also a mTOR inhibitor with Ki of 17 nM.

A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM and inhibits fatty acid synthesis with IC50 of 3.2 μM.

CH5132799 exhibits a strong inhibitory activity especially against PI3Kα with IC50 of 14 nM and also inhibits mTOR with IC50 of 1.6 µM.KX2-391 (KX01) is a highly selective non ATP-competitive Src inhibitor with GI50 of 9-60 nM in cancer cell lines .

GSK1838705A is a potent inhibitor of IGF-1R, IR and ALK with IC50 of 2.0 nM, 1.6 nM and 0.5 nM, respectivelyLY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively.

YO-01027 (Dibenzazepine, DBZ) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM for APPL and Notch, respectively.

LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM and 0.082 nM for membrane- and cell-based γ-secretase.

AMG 900 is a potent and highly selective pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 5 nM, 4 nM and 1 nM, respectively.

PF-03814735 is a novel, potent and reversible inhibitor of both Aurora A and Aurora B with IC50 of 0.8 nM and 5 nM, respectively.

PF299804 is a potent, irreversible pan-ErbB inhibitor against ErbB1, ErbB2 and ErbB4 with IC50 of 6 nM, 45.7 nM and 73.7 nM, respectively.

Crenolanib (CP-868596) is a potent and selective inihibitor of PDGFRα with IC50 of 10 nM in PDGFRα over-expressed CHO cells.

PKI-402 is a potent dual PI3K/mTOR inhibitor targeting PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ and mTOR with IC50 of 2 nM, 7 nM, 16 nM, 14 nM, and 3 nM, respectively.GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B and Aurora C with IC50 of 3.5 nM and 6.5 nM, respectively.

PHA-767491 is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.PF-04691502 is an ATP-competitive, selective inhibitor of PI3K(α/β/δ/γ)/mTOR with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM, also inhibits Akt phosphorylation on T308/S473 with IC50 of 7.5 nM/3.8 nM.

CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM, respectively.CHIR-98014 is a potent and selective GSK-3 inhibitor for GSK-3ɑ and GSK-3β with IC50 of 0.65 nM and 0.58 nM, respectively.

Anacetrapib (MK0859) is a potent and selective rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, respectively

ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM and also inhibits EGFR with IC50 of 4 μM. AT-406 is a potent IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase) inhibitor of XIAP, cIAP1, and cIAP2 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, respectively.

Wortmannin is a multi-target inhibitor of MLCK and PI3K with IC50 of 170 nM and 3 nM, also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM

PI3K/HDAC Inhibitor I is a dual PI3K and HDAC inhibitor for PI3Kɑ, HDAC1, HDAC2, HDAC3 and HDAC10 with IC50 of 19 nM, 1.7 nM, 5 nM, 1.8 nM and 2.8 nM, respectively.Canagliflozin is a highly potent and selective SGLT2 inhibitor for CHO-hSGLT2, CHO-rSGLT2 and CHO-mSGLT2 with IC50 of 4.4 nM, 3.7 nM and 2 nM, respectively.

3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM and also blocks autophagosome formation.

Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively.

MK-2461 is a potent inhibitor of c-Met, Ron, Flt1/3, PDGFRβ, Mer and FGFR1/2/3 with IC50 of 2.5 nM, 7 nM, 10 nM/22 nM, 22 nM, 24 nM and 65 nM/39 nM/50 nM, respectively.

Nocodazole inhibits Abl, Abl(E255K) and Abl(T315I) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM, respectively.

PF-5274857 is a potent and selective Smoothened (Smo) antagonist with IC50 and Ki of 5.8 nM and 4.6 nM, respectively.

RITA (NSC 652287) is a DNA damaging agent with IC50 of 2 nM and 20 nM in A498 and TK-10 cells, and also inhibits MDM2-p53 interaction by targeting to p53.

Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.

AZD4547 is a novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3 with IC50 of of 0.2 nM, 2.5 nM, and 1.8 nM, respectively.

BAY 80-6946 is a potent and highly selective reversible PI3K inhibitor for PI3Kα and PI3Kβ with IC50 of 0.469 nM and 3.72 nM, respectively.Galeterone (TOK-001, VN/124-1) is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively.

Dabrafenib (GSK2118436) is a potent ATP-competitive inhibitor of B-Raf, B-RafV600E and c-Raf with IC50 of 3.2 nM, 0.8 nM and 5.0 nM, respectively.

GDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 5 nM, 18 nM and 8 nM, respectively.

Torin 2 is a highly potent and selective mTOR inhibitor with IC50 of 0.25 nM, and also exhibits potent cellular activity against ATM/ATR/DNA-PK with EC50 of 28 nM, 35 nM and 118 nM, respectively.

NVP-TAE226, a potent dual FAK/IGF-1R, inhibiting FAK and IGF-1R with IC50 of 5.5 nM and 0.14 μM, respectively.

Desmethyl Erlotinib (CP-473420) is a free base of OSI-420, which is an active metabolite of Erlotinib which is an orally active EGFR inhibitor for human EGFR with IC50 of 2 nM.

Epiandrosterone (3β-androsterone) is a steroid hormone with weak androgenic activity which acts as a L-type Ca2+ channel antagonist.

BI-D1870 is an ATP-competitive inhibitor of ribosomal S6 for RSK1, RSK2, RSK3 and RSK4 with IC50 of 31 nM, 24 nM, 18 nM and 15 nM, respectively.

Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.

SB-269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3.

IEM 1754 dihydrobroMide is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.

U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with IC50 of 45.1 nM and 4.5 nM, respectively.

TG 100713 is a PI3K inhibitor for PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.

Camostat is a trypsin-like protease inhibitor, inhibiting matriptase and human neutrophil elastase with IC50 of 0.5 μM and 0.2 μM, respectively.Prucalopride is a selective, high affinity 5-HT receptor agonistfor 5-HT4a and 5-HT4b with Ki of 2.5 nM and 8 nM, respectively.

MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.L-NAME is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively.

IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.

PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively.

ZM-306416 is a VEGFR inhibitor, inhibiting Src, VEGFR1 and Abl with IC50 of 0.33 μM, 0.33 μM and 1.3 μM, respectively.GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl, inhibiting the proliferation of the Bcr-Abl-expressing cells with IC50 of 138 nM.

PF 477736 is a ChK inhibitor against ChK1, ChK2, VEGFR2, Yes and Fms with IC50 of 0.49 nM, 47 nM, 8 nM, 14 nM and 10 nM, respectively.

Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively.

VU 0361737 is a selective positive allosteric modulator for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively.

Pirfenidone inhibits TGF-β bioactivity by affecting TGF-β2 mRNA expression and processing of pro-TGF-β in CCL-64 cells.

Go 6983 is a pan PKC inhibitor against PKCα, PKCβ, PKCγ, PKCδ, PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.

Bay 11-7082 inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM and inactivates the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13, UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex).Dapivirine is an nonnucleoside reverse transcriptase inhibitor for HIV reverse transcriptase with IC50 of 24 nM.

GW9662 is a selective PPAR antagonist, inhibiting PPARγ, PPARα and PPARδ with IC50 of 3.3 nM, 32 nM and 2 μM, respectively. HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.

Mozavaptan (OPC-31260) is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.

Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with IC50 of 5 nM.

Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM.CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively.

Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells.

Rivaroxaban (Xarelto, BAY 59-7939) is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM, respectively.

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. Plerixafor 8HCl (DB06809, Mozobil, AMD3100) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.

Aspirin is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.

Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane.

Lamotrigine is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, respectively.

Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.

Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively.

Fosaprepitant (MK-0517, L-758,298) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.

Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively.

Palonosetron HCl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa.

Ambroxol HCl is a potent inhibitor of the neuronal Na+ channels with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, respectively.

Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.

Piracetam is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.

Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.

Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.

Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]dihydromorphine binding with IC50 of 58 nM.

Betulinic acid is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.

Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

Doxycycline HCL is a tetracycline antibiotic that commonly used to treat a variety of infections and MMP inhibitor.Clinafloxacin (PD127391) is a fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumoniae.

Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.

Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.

Monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM.

Ouabain is a selective Na+, K+-ATPase inhibitor, binds to α2 subunit and α3 subunit with Ki of 41 nM and 15 nM, respectively.

Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.

Probenecid (Benemid) is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16.Procaine (Novocaine) HCl is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.

Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.Homatropine Bromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.

Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.

Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.

Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).

Doxapram HCl inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.

Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.

Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.

Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.Vitamin D3 (Cholecalciferol) is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM.

Dequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM.

Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-?oB inhibition and free radical scavenging.

Zinc pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.

Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.

Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively. Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.

Sodium Phenylbutyrate is a transcriptional regulators that act by altering chromatin structure via the modulation of HDAC activity.

Guanabenz (WY-8678) Acetate is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively.

Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist, also inhibits CYP2C9 and 4-hydroxylation with IC50 of 10.5 μM and 8.2 μM respectively.

Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.

Pefloxacin Mesylate Dihydrate is the third generation of fluoroquinolone class of antibacterials, which inhibits Topoisomerase II activity and DNA replication.

LY404039 is a potent agonist of recombinant human mGlu2, mGlu3 receptors and rat neurons expressing native mGlu2/3 receptors with Ki of 149 nM, 92 nM and 88 nM, respectively.

IPI-145 (INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM.

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells.Oprozomib (ONX 0912) selectively inhibits CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM.

GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3/UTX with IC50 of 60 nM.

Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively.

(-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases with IC50 from 0.5-5 μM.

AMG 517 is a potent and selective transient receptor potential vanilloid-1 (TRPV1) antagonist with IC50 of <10 nM. Tenovin-1 protects against MDM2-mediated p53 degradation, which invloves ubiquitination, and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2.

ZM39923 is an JAK inhibitor for JAK1, JAK3, EFGR and TGM2 with IC50 of 4.4 μM, 7.1 μM, 5.6 μM and 10 nM, respectively.

VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively.

CEP-32496 is a RAF inhibitor for BRAF(V600E), BRAF(WT), c-Raf, Abl-1 and CSF-1R with IC50 of 14 nM, 36 nM, 39 nM, 3 nM and 9 nM, respectively.

TAK-438 is a novel potassium-competitive acid blocker (P-CAB) type antisecretory agent that reversibly inhibits gastric H+, K+-ATPase with IC50 of 19 nM at pH 6.5.

Lu-AA21004 is an oral multimodal serotonergic agent, inhibits 5-HT(1A), 5-HT(1B), 5-HT(3A), 5-HT(7) and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.

Tyrphostin AG 1296 (AG 1296) is an inhibitor of PDGFR, FGFR and c-Kit with IC50 of < 1 μM, 12.3 μM and 1.8 μM, respectively.

Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of about 50 μM.

Embelin, from the Japanese Ardisia herb, is a fairly potent, nonpeptidic, cell-permeable inhibitor of XIAP and efficiently overcomes the protective effect of XIAP XLALP to apoptosis.

is a specific agonist for NMDA receptor mimicking the action of L-glutamate.

Butein, a plant polyphenol isolated from Rhus verniciflua, inhibits EGFR tyrosine phosphorylation with IC50 of 8 μM.

Macitentana (Actelion-1, ACT-064992) is an orally active, non-peptide dual endothelin (ET)A/B receptor antagonist with IC50 of 0.5 nM/391 nM.

Pazopanib Hydrochloride (GW786034, Votrient, Armala) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively.

XL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

Idarubicin HCl (Idamycin, Zavedos, 4-demethoxydaunorubicin) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.

which is a CRBN-DDB1-Cul4A complex.

Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.

Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.

Pioglitazone hydrochloride (Actos) is a hydrochloride salt form of pioglitazone which is a cytochrome P450 (CYP)2C8 and CYP3A4 enzymes inhibitor for CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively.

Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.

Clomipramine hydrochloride (Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.

Bay 11-7082 inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM and inactivates the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13, UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex).

Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

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