Fig. 2. Effects of vialinin A, DMT, and tacrolimus on TNF-a and b-hexosaminidase release from antigen-stimulated RBL-2H3 cells or BMMCs. A is the TNF-a release from RBL-2H3 cells, B is the b-hexosaminidase release from RBL-2H3 cells, C is the TNF-a release from BMMCs and D is the b-hexosaminidase release from BMMCs. Each value represents mean ± standard deviation of triplicate determinations. Significance of differences from control values (without inhibitor) was estimated using Student’s t-test(p < 0.01).

选自 Inhibitory effects of vialinin A and its analog on tumor necrosis factor-a release and production from RBL-2H3 cells

Fig. 4. Effects of vialinin A, DMT, and tacrolimus on TNF-a production and release in antigen-stimulated RBL-2H3 cells. Each value represents mean ± standard deviation of triplicate determinations.

选自 Inhibitory effects of vialinin A and its analog on tumor necrosis factor-a release and production from RBL-2H3 cells

选自 Inhibitory effect of aqueous spinach extract on degranulation of RBL-2H3 cells

Fig. 4. Effect of GSE on cell surface expression of FceRI. (A) RBL-2H3 cells were cultured with indicated GSE concentrations for 24 h. Cell surface FceRI levels were examined by immunostaining using mIgE-DNP followed by FITC-conjugated rat IgG1 against mouse-IgE. Mouse IgG2b antibody was used as the isotype-matched negative control. Data acquisition was performed by flow cytometry. (B) Quantitative comparison of FceRI expression levels between control and GSE-treated RBL-2H3 cells from three independent experiments. (C) RBL-2H3 cells were cultured with GSE (100 lg/ml) for 24 h, followed by measuring FceRI levels after the removal of GSE and replenishment with free medium at indicated time intervals. The control was untreated cells whose FceRI levels were measured at the same time as the 0-h treatment group.选自 Anti-allergic activity of grapeseed extract (GSE) on RBL-2H3 mast cells

选自 Effect of endocannabinoids on IgE-mediated allergic response in RBL-2H3 cells

FIG. 1. Effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on interleukin (IL)-4 and IL-13 production in RBL-2H3 cells. RBL-2H3 cells were treated with various concentrations of EPA and DHA for 1 h followed by stimulation with phorbol 12-myristate 13-acetate and ionomycin (PI) for 16 h. The levels of (A, B) IL-4 and (C, D) IL-13 were determined using ELISA. Values are expressed as mean – SD from three independent experiments. **P < .01,***P < .001 versus PI-treated control.##P < .01, ###P < .001 versus normal group.

选自 Eicosapentaenoic Acid and Docosahexaenoic Acid Suppress Th2 Cytokine Expression in RBL-2H3 Basophilic Leukemia Cells

选自 Inhibitory Effect of N-Acyl Dopamines on IgE-Mediated Allergic Response in RBL-2H3 Cells

选自 Eicosapentaenoic Acid and Docosahexaenoic Acid Suppress Th2 Cytokine Expression in RBL-2H3 Basophilic Leukemia Cells

选自 Inhibitory effect of phloretin and biochanin A on IgE-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells

选自 Inhibitory effect of phloretin and biochanin A on IgE-mediated allergicresponses in rat basophilic leukemia RBL-2H3 cells