fat protein metabolism biology lecture powerpoint vcbc

8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC

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Metabolism

Catabolism

of Proteins

& Fats

Image: Hummusby Paul GoyetteFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://en.wikipedia.org/wiki/File:Hummus_from_The_Nile.jpghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:Hummus_from_The_Nile.jpg


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Catabolism of Proteins & Fats

Q:So far, in

our study of

metabolism,what hasprovided theenergy used tomake ATP?

Images: Sugar, T. PortFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/chemistry/what-is-nucleotide-adenosine-triphosphate-atp.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/chemistry/what-is-nucleotide-adenosine-triphosphate-atp.html


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Catabolism of Proteins & Fats

How do we metabolize thingsthat arent glucose?

Fats, proteinsand carbscan all

provide energy for the cell.

Basic pathways used to extractenergy from fat & protein arethe same as for carbs:

glycolysis, Krebs, ETCbutthere are some extra steps.

Images: Olive Oil, Alex Ex; Raw beef, MCBFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.htmlhttp://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.htmlhttp://www.scienceprofonline.org/chemistry/organic-chemistry-what-is-a-carbohydrate.htmlhttp://www.scienceprofonline.org/metabolism/electron-transport-chain-cellular-respiration.htmlhttp://www.scienceprofonline.org/metabolism/electron-transport-chain-cellular-respiration.htmlhttp://en.wikipedia.org/wiki/File:Italian_olive_oil_2007.jpghttp://en.wikipedia.org/wiki/File:Standing-rib-roast-MCB.jpghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:Standing-rib-roast-MCB.jpghttp://en.wikipedia.org/wiki/File:Italian_olive_oil_2007.jpghttp://www.scienceprofonline.org/metabolism/electron-transport-chain-cellular-respiration.htmlhttp://www.scienceprofonline.org/chemistry/organic-chemistry-what-is-a-carbohydrate.htmlhttp://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.htmlhttp://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.html


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Organic Molecules -Proteins

Dehydration synthesis is the chemical reaction that joins amino acids into polypeptide.

Q: What reaction breaks down polypeptides into amino acids?

From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.html


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Protein Catabolism

Image: Protein catabolism, BoumphreyfrFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://commons.wikimedia.org/wiki/File:Protein_catabolism.pnghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://commons.wikimedia.org/wiki/File:Protein_catabolism.png


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.

How do we metabolize protein?

Excess amino acidscan be used to synthesize pyruvate, acetyl CoA, and ketogluterate, which

enters the Krebs cycle.

http://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.html


8/18Image: Cellular Respiration, Regis Frey

How do we metabolize protein?

Excess amino acids can be used to synthesize pyruvate, acetyl CoA, and ketogluterate, whichenters the Krebs cycle.

http://en.wikipedia.org/wiki/File:CellRespiration.svghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:CellRespiration.svg


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How do we metabolize fats?

Q:Fats and oils are made fromwhich two kinds of molecules?

Before these fats can be

broken down to releaseenergy, they must beconverted to smaller units.

The first step is to break thebonds between the glyceroland the fatty acids.

http://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.html


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Glycerol is a 3-carbon moleculethat is converted intoglyceraldehyde-3-phosphate.

Because glyceraldehyde-3-phosphate is involved in one ofthe steps in glycolysis, it can

enter the glycolysis pathway.

http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.html


11/18Image: Glycolysis, Regis Frey




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These long molecules (typically 14 to 20 carbons long) must also be processed beforethey can be further metabolized.

1. Enter the mitochondrion, where each long chain of carbons that makes up thecarbon skeleton is hydrolyzed (split by the addition of a water molecule) into 2-carbon fragments.

2. Each of the 2-carbon fragments is converted into acetyl. Coenzyme A is added tothe acetyl, and the ____________ goes into _______ ______.

C C

How do we metabolize fatty acid tails?

http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.html


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Krebs Cycle(a.k.a Citric Acid Cycle)

How do we metabolize fatty acid tails?

Acetyl-CoA--

Image: Cellular Respiration, Regis FreyFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com


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.


http://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.html


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Metabolic Processes Bottom Line

Every cell acquires __________.

Metabolism requires energy from_______ or from ___________ of

nutrients.

Energy is ultimately converted to_____ .

is used to do cellular work.ATP

Image: Jumping rope, Meagan E. KleinFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://en.wikipedia.org/wiki/File:Jumprope_navy.jpghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:Jumprope_navy.jpg


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Confused?Here are links to fun resources that further explain

cellular respiration:

Metabolism of Proteins & Fats Main Pageon the VirtualCell Biology Classroom ofScience Prof Online.

Cellular Respirationanimation by Jay Phelan, What is Life? AGuide to Biology, W. H. Freeman & Co.

Break It Down Againmusic video by Tears for Fears.

How NAD+ Worksanimation and quiz from McGraw-Hill.

Glycolysisanimation and quiz from McGraw-Hill.

Kreb Cycle Animation & Quiz 1from McGraw-Hill.

Kreb Cycle Animation & Quiz 2from McGraw-Hill.

Electron Transport Chainanimation from Molecular & CellularBiology Learning Center.

Food Moleculesvideo from HowStuffWorks, a Discovery company.

The Protein Songridiculous but funny song by Ruan0

Grease (Is the Word) sung by Frankie Valli.

(You must be in PPT slideshow view to click on links.)

http://www.scienceprofonline.com/vcbc/catabolism-proteins-fats-main.htmlhttp://www.scienceprofonline.com/http://www.sumanasinc.com/webcontent/animations/content/cellularrespiration.htmlhttp://www.youtube.com/watch?v=VzNvpHxWO8chttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_nad__works.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_glycolysis_works.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_1_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_2_.htmlhttp://vcell.ndsu.edu/animations/etc/index.htmhttp://videos.howstuffworks.com/discovery/29544-assignment-discovery-food-molecules-video.htmhttp://www.youtube.com/watch?v=qXzE74Kw_Fwhttp://www.youtube.com/watch?v=sGoiVgbpJz8http://www.youtube.com/watch?v=sGoiVgbpJz8http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.youtube.com/watch?v=sGoiVgbpJz8http://www.youtube.com/watch?v=sGoiVgbpJz8http://www.youtube.com/watch?v=qXzE74Kw_Fwhttp://videos.howstuffworks.com/discovery/29544-assignment-discovery-food-molecules-video.htmhttp://vcell.ndsu.edu/animations/etc/index.htmhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_2_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_2_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_2_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_1_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_1_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_1_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_glycolysis_works.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_nad__works.htmlhttp://www.youtube.com/watch?v=VzNvpHxWO8chttp://www.sumanasinc.com/webcontent/animations/content/cellularrespiration.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/vcbc/catabolism-proteins-fats-main.htmlhttp://www.cst.cmich.edu/users/schul1te/animations/fermentation.swf


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Assignment

At the end of somelectures, I will give yousome type of in-classassignment orhomework to evaluate

your understanding oftodays topic.

This assignment willalways be open-book.

Today, if assigned youwill be completing anessay questionon thetopic of Catabolism ofProteins & Fats.

From the Virtual Cell Biology Classroom on ScienceProfOnline.com

See the ScienceProfOnlineVirtual Cell BiologyClassroom: Metabolism of Fats & Proteinsfor a

printable Word .doc of this assignment.

Image: Hummusby Paul Goyette
http://www.scienceprofonline.com/http://www.scienceprofonline.com/http://en.wikipedia.org/wiki/File:Hummus_from_The_Nile.jpghttp://en.wikipedia.org/wiki/File:Hummus_from_The_Nile.jpghttp://www.scienceprofonline.com/http://www.scienceprofonline.com/


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fat protein metabolism biology lecture powerpoint vcbc

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