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Donor Eggs Increasingly Used for IVF, With Rising Success

The use of donor eggs -- whether from family, friends or strangers -- by

infertile patients undergoing in vitro fertilization (IVF) has risen in the last

decade, and results have been favorable, with an increasing number of healthy

babies born at term. Today women are increasingly using donated eggs to get

pregnant, with often good results because the donor eggs are from young,

healthy women, they have a good chance of success, generally regardless of

the recipient's age.

In spite of high success rate of assisted reproduction methods all couples are

not able to achieve pregnancy by using their own eggs. These couples have

only two options to have the family - receive a donated egg or sperm or get

through a tedious process of adoption.

The Donor Egg Program was established to help women who are unable to use

their own eggs (oocytes) to achieve pregnancy. A Donor Egg IVF cycle is an IVF

cycle in which the eggs from a Donor are used instead of a patient's own eggs.

Donor eggs may be combined with the male partner's sperm or with Donor

sperm. Donor egg IVF is an appropriate treatment option for women with

decreased ovarian reserve because of advanced reproductive age, premature

ovarian failure and surgical menopause. It is also suitable for women carrying a

genetic mutation and for those with multiple failed IVF cycles using own eggs.

Poor egg quality is sometimes determined during an IVF attempt.

Donor Egg IVF opens up a world of possibilities and new hope for couples who

have struggled to conceive. Once your pregnancy is established, your body

takes over and there is nothing that can distinguish a Donor Egg pregnancy

from a natural pregnancy. You have the opportunity to carry and give birth to

your child.

Here are the most frequently asked questions about donor egg IVF cycle.

1. For whom is the donor egg advisable?

There are two primary indications for Egg Donation Treatment. They are age

and ovarian reserve. As a woman increases in age, her eggs age as well.

Women will experience a significant decline in fertility starting in their mid-

30’s. The decline becomes more pronounced as a woman reaches her 40s with

a near zero pregnancy rate utilizing her own eggs by age 45. Decreased ovarian

function can occur in younger women and in severe cases complete ovarian

failure (menopause) can occur in women under the age of 40. This decline is

more rapid after the age of 37 and is seen in the quality as well as quantity of

eggs produced.

2. Who are the Egg Donors?

Most of the time egg donation process is anonymous and confidential. The

identity of the egg donor and the egg recipient is not revealed unless

otherwise stipulated. The Egg Donors are between the ages of 21 to 29, usually

having at least one child of their own and have undergone a complete

psychological and medical evaluation and are screened for infectious diseases

like HIV and hepatitis B. The intelligence level, height, weight and looks of the

donor are also considered. Only after the screening process is complete, the

donor is recruited into the egg donor program.

3. What does the Donor Egg IVF procedure involve?

Recipient couples are asked to select one or more donors whom they find

suitable. One of the selected egg donors will be offered to a recipient couple

upon availability of the egg donor. Final approval of the specific selection is

always made by the recipient couple. The cycles of the donor and recipient to

accomplish fresh embryo transfer whenever possible is co-ordinated.

Synchronization of cycles includes using a series of medications to facilitate a

hospitable uterine environment for transfer of embryos. Once the Donors eggs

are mature, usually in 11-12 days, the egg retrieval procedure will be done

under anaesthesia using ultrasound guidance. The husband will provide his

semen sample and fertilization will be carried out in the laboratory. Two to five

days later 2-5 embryos will be transferred with great care into the Recipient's

uterus. If there are embryos in excess of the number for safe transfer,

Vitrification of additional embryos is available and is strongly recommended.

Vitrified embryos (frozen embryos) can be used for subsequent attempts at

pregnancy whether or not the fresh transfer is successful, and still produce

high rates of success.

4. Is there a waiting list to start Donor Egg IVF treatment?

Normally donor egg recipient is not required to join a waiting list. Donor Egg

IVF cycles can match one donor to one recipient (sole match) or one donor to

two recipients (shared match). Regardless of whether a patient chooses a sole

or shared match, she can begin treatment immediately and will not be

required to wait for a donor. An extensive pool of fully-screened, immediately

available egg donors and list of frozen donor eggs is available with the clinic.

The only waiting period is the duration required to synchronise the Egg Donor's

menstrual cycle with the Recipients.

5. How can I be a Donor Egg Recipient if I live out of town or international

patient?

The IVF clinic has the vast experience working with out-of-town and

international patients. The physician is very skilled at coordinating your care

regardless of where you live; rest assured they will make the process as easy as

possible for you. From all over the world, couples come for Donor Egg IVF and

the clinic is adept at minimizing inconveniences and your time away from

home. For many patients, the time from an initial contact with IVF specialists

to initiation of their Donor Egg IVF cycle can be a little as one month or less.

6. If the patient lives out of the town or internationally, how often will he need

to visit and how long he needs to stay?

Patients from overseas or abroad need to be with IVF specialist for three to

five days from the day of the Donor's egg retrieval and can travel back home

immediately after the Embryo Transfer. The initial coordination and evaluation

of test results can be done through Email correspondence. Your partner can

come with you directly on the day of the Donors Egg retrieval and provide his

Semen sample. Alternatively, he can travel anytime beforehand and freeze his

semen sample at the IVF clinic.

7. What are the legal aspects of egg donation?

The ICMR guidelines allow commercial egg donation, provided it is anonymous

and confidential. The egg donor has no rights over her eggs once they leave

her body, and signs a contract agreeing to this.

8. Do I need to divulge to anyone that I used donated eggs?

It is your decision if, and to whom, you choose to share the genetic source of

your child. It is strongly recommended that you do share the information with

your Obg / Gyn and ultimately with your child’s paediatrician, so they can

better take care for both you and your child. It is also advisable to share the

information with your child once he grows up.

Rotunda IVF and Keyhole Surgery Clinic based in Mumbai, India offers one of

the most comprehensive Donor Egg IVF programs in the country. We have a

large and diverse pool of immediately available egg donors as well as excellent

success rates.

Patients from all over the world travel to us for this highly effective treatment.

Our Fertility Specialists are skilled at coordinating the care for patients who live

locally or internationally. We have a vast experience in Donor Egg IVF and our

success rates are among the best in the country. We provide internationally

comparable services and success rates. For donor egg cycles, our success rate

is about 60% per cycle.

You can depend on personalized, compassionate care and attentions from your Fertility

specialist who will hand hold you through the entire process. For further assistance on

donor egg ivf process, ivf related any faqs, egg donor program, sperm donor program, you

may contact us at http://www.rotundaivf.in/donoreggivf.html# or

http://www.testtubebabyclinic.com/donoreggivf.php or you can call us on 91 22

27830100.

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