fabienne cournarie director of public affairs , simv france

Fabienne CournarieFabienne CournarieDirector of Public Affairs, SIMVDirector of Public Affairs, SIMV

FranceFrance

ETPGAH Mirror Groups meeting ETPGAH Mirror Groups meeting Tuesday 23 November 2010Tuesday 23 November 2010

The French Network for The French Network for Animal HealthAnimal Health

Why?

Implementation, at the national level, of the EU guidelines and

objectives defined in the ETPGAH Action Plan = « Mirror

Groups »

How?

• Initiative of the French Ministry of Agriculture, launched in

May 2007

French Network for Animal HealthFrench Network for Animal Health

Government Government

Regulatoy authoritiesRegulatoy authorities


Industry Industry

Vet schoolsVet schools

Public research Public research organismsorganisms

Diagnostic labsDiagnostic labs

• Ministry of Agriculture (and Fisheries)• French Agency for Sanitary Safety (ANSES)• Animal Health Industry, united in SIMV• National Veterinary Schools (ENV)• National Institute of Agronomy Research (INRA)• Agricultural Research Centre for International Development (CIRAD)• Technical Veterinarians Union (SNGTV)• Sanitary Defence Groups (farmers) (FNGDS)• Public Veterinary Diagnostic Laboratories (ADILVA)

Who?Who?

FarmersFarmers

Vet organisationsVet organisations

New members in 2010:New members in 2010:

• AVEF : Veterinary organization for horses welfare

• AFVAC : Veterinary organization for companion animal care

• INSERM : Public research organism

• ITAB : Technical institute of organic farming


Who?Who?

Stakeholders covering the whole range of animal health professionals

MissionsMissions


EUROPEFP-7

Public research Private research

Users:Veterinarian

Farmers

French Authorities

StructureStructure


To provide solutions to the

immediate needs

Emerging diseases

Antimicrobial resistance

Steering Committee

EuropePublic Private

cooperation

4 working groups

Working group 1: Working group 1: ““orphan drugs” availability orphan drugs” availability


11. Solved Issues. Solved Issues

Either by maintaining enough stocks in case of TU or by succeeding in the idea of preparing a CTD

• Anthrax vaccine (sporadic cases): TU• Q fever : CTD in progress• tuberculin for ID tests • Local anaesthetics for ruminants: proposal made to CVMP• Oral sedation for ruminants : CTD? • Dexamethasone ovine• Ruminant cryptosporidosis : CTD in progress

Very positive output. Having all actors (regulatory authorities, manufacturers, veterinarians and farmers) around the same table has definitely helped to define rapid and pragmatic solutions.

Working group 1: Working group 1: ““orphan drugs” availability orphan drugs” availability


2. Issues which require a European involvement2. Issues which require a European involvement

• Paratuberculosis vaccine: an attenuated form is required• Histomonosis: no treatment available• Products for bee disease treatment

To evaluated needs at the level of Europe To federate expertise and means

Working group 2: Working group 2: emerging diseaseemerging disease


1.1. Concerted list of immediate (“operational”) Concerted list of immediate (“operational”) research needs:research needs:

blue tongue is a priorityblue tongue is a priority

• Epidemiology, diagnostic tools, molecular typing, BTV status in wildlife…

• Consequences on reproduction performances, on husbandry practices

• Economical impacts (direct and indirect)• Vector biology and control measures• Vaccines (safety and efficacy in “minor species”)

2.2. Longer-term research: pathogenesis, immunology Longer-term research: pathogenesis, immunology


RFSA achievements on blue tongue:RFSA achievements on blue tongue:

• Government funded research programs (total of 1,5 M€ for Short

Term perspectives) : 10 projects were funded

• Meeting on RFSA initiative for the review of the on going research

projects on BTV (March 18th 2010 ) : among them 4 priorities were

selected

Success because achieved in less than 2 years

Working group 2: Working group 2: emerging diseaseemerging disease

Working Group 3: EuropeWorking Group 3: Europe


1.1. Links with EMIDA – ERA NET, DiscontoolsLinks with EMIDA – ERA NET, Discontools

First EMIDA common calls: First EMIDA common calls:

77 pre-proposals were received, 45 were shortlisted, 77 pre-proposals were received, 45 were shortlisted, only 12 were identified for funding, 8 projects have only 12 were identified for funding, 8 projects have french partnersfrench partners

projects with french partners:projects with french partners:

““vector borne disease” : 2vector borne disease” : 2““major infectious diseases affecting major infectious diseases affecting

production”: 5production”: 5““aquaculture”: 1aquaculture”: 1



2.2. FP7FP7

Analyse the European project calls Analyse the European project calls : analyse the : analyse the reflection paper of FP7 projects calls and share the reflection paper of FP7 projects calls and share the information with its partnersinformation with its partners

Propose to the European commission Propose to the European commission : based on : based on the FP7 projects calls and/or on the FP7 projects calls and/or on RFSA coordinated topic priorities , propose projects to the European , propose projects to the European commissioncommission



List of topics proposed to the FP7 theme 2 Program committee by List of topics proposed to the FP7 theme 2 Program committee by the french ETPGAH mirror group in January 2010the french ETPGAH mirror group in January 2010

Main line 1, Animal health and non food-borne zoonosesMain line 1, Animal health and non food-borne zoonoses

Topics:

• Ruminant pathogenic mycoplasmas: from genomics to the development of new control strategies• The assessment of the within-herd dynamics of endemic pathogens in pigs

The priority of these topics has been confirmed in september 2010



Main line 2, Food borne zoonoses :Main line 2, Food borne zoonoses :

Main line 3.1 Animal health and non-food borne zoonoses:Main line 3.1 Animal health and non-food borne zoonoses:

List of topics proposed to the FP7 theme 2 Program committee by List of topics proposed to the FP7 theme 2 Program committee by the french ETPGAH mirror group in January 2010 (continue)the french ETPGAH mirror group in January 2010 (continue)

Topics: • Knowledge of Trichinella nurse cell• Trichinella control

Topic: • Alternative/complementary medication in organic/low-input livestock systems



New topics proposed to the FP7 theme 2 Program committee by New topics proposed to the FP7 theme 2 Program committee by the french ETPGAH mirror group in September 2010 the french ETPGAH mirror group in September 2010

Q Fever• “Resistant forms of C. burnetii: characterisation, role in maintenance and transmission of the disease, exploration of prophylactic strategies”

• “Study of genomic plasticity and biodiversity of C. burnetii strains populations and relationships to pathoadaptation and epidemiological factors”

Bee diseases• “Development and Harmonization of tests in diagnosis and bee research (HARMONY)”

Main line: 3.1: Animal health and non food-borne zoonosesMain line: 3.1: Animal health and non food-borne zoonoses


Topic: Integrating systems biology outputs to generate cutting edge vaccines and predictive protection in farm animals

Main line 1.2: 'Omics technologies', systems biology and other basic sciences in farm animals.

Gaps: Bioinformatics, systems biology, immunology Epigenetics Host-pathogen interaction, identification of protective antigens in complex pathogens Cutting edge vaccinology platform

2.2. FP7 (continue)FP7 (continue)




Main line 3.2: Food-borne zoonoses, antimicrobial resistance.

Gaps:

antimicrobial resistance

2.2. FP7 (continue)FP7 (continue)

Topic: Management of increased antimicrobial resistance in animal populations

Group 4: Private-publicGroup 4: Private-public cooperationcooperation


1. Identification of subjects of interest for possible private-public cooperation: done

• Antimicrobial resistance

2. To define the rules for a productive PPP cooperation

• (resolution of legal aspects, technical issues…): next step

3. Links with ARIIS : • Brings together all industries involved in health (human,animals…)

• Calls for projects from the French government to create institute to enhance the translational research (hospital, university, biotech/pharma companies)

• Infectious disease institute was proposed including zoonoses


Research on epidemiology and physiopathology of bacterial disease in animals

Alternative to antibiotics

How pathogenic are transmitted from animals to human? Contact, alimentation, environment

Economics analysis

Which strategies for the treatment of animals with antibiotics?

Antimicrobial resistance: 5 prioritiesAntimicrobial resistance: 5 priorities

A national committe for the cautious use of antibiotics will be A national committe for the cautious use of antibiotics will be launched in January 2011launched in January 2011

http://www.rfsa.net/

http://www.rfsa.net/

fabienne cournarie director of public affairs , simv france

Documents

animal healthto

animal healtheuropefp

animal healthwhy

animal health1

animal health2

animal healthwho

immunologyfrench network

animal healthrfsa achievements