extending mendel's laws a question that breeders often have is
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Extending Mendel's Laws A question that breeders often have is "what is the genotype of an organism that displays the dominant phenotype?". - PowerPoint PPT PresentationTRANSCRIPT
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Extending Mendel's Laws
A question that breeders often have is "what is the genotype of an organism that displays the dominant phenotype?"
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For example, in a breed of dog in which the gene for black coat is dominant (B) over the gene for red coat (b) colour, a dog with black coat colour could have either of two possible genotypes: BB or Bb
To determine whether the black coat colour is homozygous (BB) or heterozygous (Bb), it is necessary to perform a test cross.
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TEST CROSSA specific cross to determine the unknown traits in an individual. In other words to determine whether the organism is Homozygous or Heterozygous
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Lets revisit the example
A dog breeder thinks that his dark colour dog is carrying a gene for no red colour coat. Prove it!
Possible Genotypes
BB or Bb
Let B represent black coat colourLet b represent red coat colour
Cross his dog with a homozygous recessive red colour coat dog
B_ X bb
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B_ X bb
The phenotype of the offspring resulting from the test cross will reveal the genotype of the mystery dog. The homozygous recessive parent can only contribute the recessive allele (b) to the offspring, therefore the phenotypes will indicate the alleles from the other parent (the mystery dog)
b Bbb Bb
b Bbb Bb
If the mystery dog is Homozygous (BB) then it can only contribute (B) and all the offspring would have a black coat colour
If the mystery dog is Heterozygous (bb) then it can either contribute (B) or (b) and we would expect both colour coats
B B B b
Bb
BbBb
bb
bb
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Dominance
Complete Dominance a kind of dominance wherein the dominant allele completely masks the effect of the recessive allele in heterozygous conditions
this type of dominance resemble Mendel's pea plants
eg. What are the chances of two heterozygous tall plants producing a short plant.
T TT Ttt Tt tt
T t
25%
Dominance and recessiveness explain some simple forms of inheritance. For most traits, however, inheritance patterns are more complex.
25%
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Incomplete Dominance
one trait is not dominant over another, each allele has some degree of influence eg. Snapdragons, pink flowers occur when red and white flowers are crossed.Let R represent Red ColourLet W represent White
In what ratio will red, white and pink flowers occur if 2 pink flowers are crossed?
RW X RW
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Similar to incomplete dominance, codominance is an inheritance pattern in which neither allele is dominant to the other. Both alleles are completely expressed at the same time.
Codominance a kind of dominance in which a heterozygote shows the phenotypic effect of both alleles fully and equally.
eg. in roan cattle the expression of one allele is not masked by the expression of the other.
Homeworkpg. 134 #2,3pg. 138 #16pg. 141 #1
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So far we have discussed traits that involve only two alleles per gene. But for most genes, more than 2 alleles exist in a population. The existence of multiple alleles means that there maybe many possible genotypes for a particular gene, and many possible phenotypes.
Multiple Alleles three or more forms of a gene
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eg. Blood type in humans involves three alleles
IA - type A allele IB - type B allele i - type O allele
A person can have one of four blood types: A, B, AB, or O.The letters refer to the two types of carbohydrates, A and B, that are found on the surface of the red blood cells.
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There are six possible ways to pair the alleles, six possible genotypes.
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Blood transfusion: Must be sure the donor's antigens (causing an immune response) will not cause clumping with recipient's antibodies (chemical for defense)
If the blood types are incomnpatible, the recipient will have a potentially fatal immune response
Blood Type
Marker on rbc's
Antibodies Present
Can give blood to
Can receive blood from
A A A
B A, AB A, O
B B B A B, AB B, OAB AB
ABNone AB A, B, AB,
OO A
BA, B, AB, O
O
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Eye ColourLet B - brown eyesLet b - blue eyesLet G - green/hazel eyesLet g - light coloured eyes
Lets cross Heterozygous ParentsBbGg X BbGg
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Homeworkpg. 145 #1, 5, 6, 7, 11
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