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Department of Chemical & Materials Engineering ESP# _____ - _____ - _____Experiment Safety Plan

An Experiment Safety Plan (ESP) is required for every experiment conducted within the Department, including those experiments performed by Department Employees/Students at a location away from Jett Hall. The purpose of the ESP is to assure the safety of all by identifying the safest possible methods to conduct an experiment. By signing below the individual(s) conducting the experiment, Chemical Hygiene Officer (CHO), and the faculty advisor acknowledge responsibility for the following requirements.

1) Appropriate Personal Protective Equipment (PPE) must always be worn while in the lab (as described in the ESP). The minimum required PPE to enter a research/teaching lab in Jett Hall is (1) long pants, (2) closed toe shoes, (3) lab coat or long sleeve shirt, and (4) safety glasses with side shields.

2) For safety reasons, no researcher is permitted to work alone in the lab at any time. Because the labs are open 24/7, there may be occasions (such as a late night or over weekends) when there are no other people working in the lab. If you plan to work during a time when the lab might be expected to be empty, please plan ahead and coordinate your work schedule with another lab member.

3) Training must be completed prior to working the experiment in the lab. The minimum required training to enter the lab can be completed through EH&S and includes the following courses: (1) Employee & HAZCOM Safety, (2) Lab Standard, (3) Hazardous Waste Management and (4) the SACHE certification "Basics of Laboratory Safety." Researchers must attend the annual lab refresher seminar. Other training may be required by the CHO or EH&S personnel based on the ESP review.

4) ESP approval occurs in two phases. Phase I is the preparation of a written safety plan. Upon approval of the written plan, researcher(s) may order equipment and necessary supplies, and begin to assemble experiment. Phase I also includes an evaluation by CHO (and if appropriate by EH&S) to establish controls of hazardous operations, avoid the purchase of inappropriate supplies, and establish expected waste(s) streams. Phase II approval requires evaluation of the assembled experiment, and a “dry run” of the experimental procedure or Emergency Shutdown Procedure. High Hazard work may be subject to approval by official university boards, including any work with radioactive materials or radiation producing machines, certain biological materials, animals and/or human subjects.

Date

ESP Phase I approval:Department Head

ESP Phase II approvalChemical Hygiene Officer

5) By signing below, both faculty advisor and researchers(s) understand that the CHO can approve/disapprove any part of the ESP. The CHO can further assemble a committee of individuals with appropriate technical or EH&S background to assist in reviewing the ESP. It is the goal of the CHO to help the researcher(s) find the safest method(s) of conducting an experiment. The CHO, or any faculty member, may stop lab activity of individuals not following good lab practices.

Name Signature Date

Faculty Advisor

Researcher

Researcher

COE Safety

EH&S (at request of CHO)

NMSU CHME ESP (rev. 08/20/2015) 1

NMSU Chemical Engineering Experiment Safety Plan (ESP)This document must be typed.

Name/Title of Experiment: Briggs-Rauscher Reaction

Building and Room Number:

Location within Room: Fume Hood / Tabletop in an undefined location (such as in a school gymnasium).

Emergency Contacts: EMERGENCY 911

Department Engineer Meng Zhou (575) 646-1214

Faculty Advisor

Department Head David Rockstraw (575) 635-9539

Responsible Researcher

Required attachments to the ESP:

Attachment 1: Experiment Scope

Attachment 2: Drawing of the laboratory or pilot area

Attachment 3: Normal Operations, Startup and Shutdown Procedures

Attachment 4: Emergency Shutdown Procedure and medical emergency instructions.

Attachment 5: Waste Management Procedure

Attachment 6: Hazard Identification and Mitigation

Attachment 7: Material Safety Data Sheets


Attachment 1 – Experiment Scope

Provide a concise description of the laboratory experiment to be undertaken.

1. Explain why the work is being performed, the goal(s) of the experimental program

2. Provide the stoichiometry of any chemical reactions and their heats of reaction

3. Demonstrate the inherent thermal safety of your experiment through calculation or through the use of accelerating rate calorimetry data.(http://chme.nmsu.edu/research/ehs/experimental-safety-plan-esp/esp-energetics-calculation/ )

4. Include a complete list of all chemicals (reactants and products) involved in the work.

5. Include a complete list of all equipment (e.g. autoclave, centrifuge, pump, heat bath etc.) involved in this work

This experiment is to demonstrate a chemical engineers skills to students in grades school and middle school.

Goals of this experiment:

To demonstrate chemistry to school age children To encourage students to pursue chemical engineering as a degree course

Taken from: Oscillating reaction - Briggs-Rauscher reaction. University of Leeds: http://www1.chem.leeds.ac.uk/delights/texts/expt_11.html

“In the BR reaction the evolution of oxygen and carbon dioxide gases and the concentrations of iodine and iodide ions oscillate. The somewhat simplified mechanism of this reaction can be represented by the following overall transformation:

IO3- + 2 H2O2 + CH2(COOH)2 + H+==> ICH(COOH)2 + 2 O2 + 3 H2O (11.1)

This transformation is accomplished through two component reactions:

IO3- + 2 H2O2 + H+==> HIO + 2 O2 + 2 H2O (11.2)

HIO + CH2(COOH)2==> ICH(COOH)2 + H2O (11.3)

The first of these two reactions can occur via two different processes, a radical process and a nonradical process. Which of these two processes dominates is determined by the concentration of iodide ions in the solution. When [I-] is low, the radical process dominates; when [I-] is high, the nonradical process is the dominant one. The second reaction (eq. (11.3)) couples the two processes. The reaction consumes HIO more slowly than that species is produced by the radical process when that process is dominant, but it consumes HIO more rapidly than it is produced by the nonradical process. Any HIO which does not react by eq. (11.3) is reduced to I- by hydrogen peroxide as one of the component steps of the nonradical process for reaction (11.2). When HIO is produced rapidly by the radical process, the excess forms the iodide ions, which shut off that radical process and start the slower nonradical process. Reaction (11.3) then consumes the HIO so rapidly that not enough is available to produce the iodide ion necessary to keep the nonradical process going, and the radical process starts again. Each of the


http://www1.chem.leeds.ac.uk/delights/texts/expt_11.html

http://chme.nmsu.edu/research/ehs/experimental-safety-plan-esp/esp-energetics-calculation/

processes of reaction (11.2) produces conditions favorable to the other process, and, therefore, the reaction oscillates between these two processes.

The detailed explanation requires attention to the individual steps of the two processes. If iodide ions are present in sufficient concentration, the reaction follows the nonradical process, reaction (11.2). The iodide ions react rather slowly with iodate ions,

IO3- + I- + 2 H+==> HIO2 + HIO (11.4)

The iodous acid (HIO2) is further reduced to hypoiodous acid (HIO),

HIO2 + I- + H+==> 2 HIO (11.5)

The hypoiodous acid is then reduced by hydrogen peroxide,

HIO + H2O2==> I- + O2 + H+ + H2O (11.6)

The net transformation represented by eq. (11.2) is obtained by the stoichiometric addition of eq. (11.4) + eq. (11.5) + eq. (11.6).

Because reaction (11.2) is slower than reaction (11.3) under these conditions, so much HIO is used up by reaction (11.3) that reaction (11.6) cannot replenish the I- consumed in reactions (11.4) and (11.5); the [I-] keeps diminishing.

Once the iodide ions have been sufficiently depleted, the nonradical process becomes very slow, and the radical process for reaction (11.2) can take over. This process involves the five steps [3].

IO3- + HIO2 + H+==> 2 IO2

· + H2O (11.7)

IO2· + Mn2+ + H2O ==> HIO2 + Mn(OH)2+ (11.8)

Mn2+ + H2O2==> Mn2+ + H2O + HOO· (11.9)

2 HOO·==> H2O2 + O2 (11.10)

2 HIO2==> IO3- + HIO + H+ (11.11)

These steps, when combined in the stoichiometry of 2 (eq. (11.7)) + 4 (eq. (11.8)) + 4 (eq. (11.9)) + 2 (eq. (11.10)) + eq. (11.11), have the overall result given by eq. (11.2). A significant feature of this process is that, taken together, the first two steps (eqs. (11.7) and (11.8)) are autocatalytic - they produce 2 HIO2 for each one consumed. Therefore, the rate of these steps increases as they occur. Because this radical process is autocatalytic, it causes a rapid increase in the concentration of HIO, which is produced by the disproportionation of HIO2 (eq. (11.11)). This process does not rapidly consume all the iodate in the solution, because the last step is second order in the catalytic species. Thus, as its concentration increases because of the autocatalytic nature of the early steps, HIO2is ever more rapidly consumed in this last step, and the sequence of the reactions quickly reaches a steady state.

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Equations (11.8) and (11.9) indicate the function of the manganese catalyst. The manganese is oxidized in reaction (11.8) and reduced in reaction (11.9). Its catalytic effect in the reaction is accounted for through its providing the means for reducing IO2

·radicals to HIO2, thereby completing the autocatalytic cycle of equations (11.7) and (11.8).

The hypoiodous acid produced by the radical process reacts with malonic acid by reaction (11.3). However, the radical process is faster than reaction (11.3), and the excess HIO reacts with hydrogen peroxide by reaction (11.6) to create I-, which shuts off the radical process and returns the system to the slow nonradical process initiated by reaction (11.4).

The dramatic color effects arise because reaction (11.3) does not take place in a single step, but by the sequence of reactions (11.12) and (11.13).

I- + HIO + H+==> I2 + H2O (11.12)

I2 + CH2(COOH)2==> ICH(COOH)2 + H+ + I- (11.13)

The solution turns amber from the I2 produced through reaction (11.12), when the radical process maintains [HIO] greater than [I-]. The excess HIO is converted to I- through the reaction with H2O2 (eq. (11.6)). The solution suddenly turns dark blue when [I-] becomes greater than [HIO], and the I- can combine with I2 to form a complex with the starch. With [I-] high, reaction (11.2) switches to the slow nonradical process. The color then fades as reaction (11.3) consumes iodine faster than it is produced. When the system switches back to the rapid radical process, the cycle is repeated.

The above reaction steps constitute a skeleton mechanism for the BR oscillating reaction. Upon initial mixing of the solutions, IO3

- reacts with H2O2 to produce a little HIO2. The HIO2 reacts with IO3

- in the first step of the radical process (eq. 11.7). The autocatalytic radical process follows, rapidly increasing the concentration of HIO. The HIO is reduced to I- in a reaction with H2O2 (eq. 11.6). The large amount of HIO reacts with I-, producing I2 (eq. 11.12). The I2 reacts slowly with malonic acid, but the concentration of HIO, I2 and I- all increase, because reaction (11.2) is faster than reaction (11.3). As [I-] increases, the rate of its reaction with HIO2 (eq. 11.5) surpasses that of the autocatalytic sequence of reactions (11.7) and (11.8). The radical process is then shut off, and the accumulation of reduced iodine is consumed by reaction (11.3) operating through the sequence of reactions (11.12) and (11.13). Eventually [I-] is reduced to such a low value that reactions (11.7) and (11.8) become faster than reaction (11.5), and the radical process takes over again. This oscillating sequence repeats until the malonic acid or IO3

- is depleted.

Chloride ion concentrations in excess of 0.07 M suppress the oscillations. Therefore the vessels used for the preparation of the solutions must be clean and distilled water must be used for all preparations.”

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References:

School of Chemistry. (2010, 5 12). Oscillating reaction - Briggs-Rauscher reaction. Retrieved from University of Leeds: http://www1.chem.leeds.ac.uk/delights/texts/expt_11.html

IO3- + 2 H2O2 + CH2(COOH)2 + H+==> ICH(COOH)2 + 2 O2 + 3 H2O (11.1)

IO3- + 2 H2O2 + H+==> HIO + 2 O2 + 2 H2O (11.2) ΔHrxn = 166.7 kJ/mol

HIO + CH2(COOH)2==> ICH(COOH)2 + H2O (11.3) ΔHrxn = ? kJ/mol

IO3- + I- + 2 H+==> HIO2 + HIO (11.4) ΔHrxn = 553.6 kJ/mol

HIO2 + I- + H+==> 2 HIO (11.5) ΔHrxn = 186.6 kJ/mol

HIO + H2O2==> I- + O2 + H+ + H2O (11.6) ΔHrxn = -286.8 kJ/mol

IO3- + HIO2 + H+==> 2 IO2

· + H2O (11.7) ΔHrxn = -305.7 kJ/mol

IO2· + Mn2+ + H2O ==> HIO2 + Mn(OH)2+ (11.8) ΔHrxn = 249.7 kJ/mol

Mn2+ + H2O2==> Mn2+ + H2O + HOO· (11.9) ΔHrxn = -84.7 kJ/mol

2 HOO·==> H2O2 + O2 (11.10) ΔHrxn = -214.6 kJ/mol

2 HIO2==> IO3- + HIO + H+ (11.11) ΔHrxn = -367.0 kJ/mol

I- + HIO + H+==> I2 + H2O (11.12) ΔHrxn = -363.7 kJ/mol

I2 + CH2(COOH)2==> ICH(COOH)2 + H+ + I- (11.13) ΔHrxn = ? kJ/mol

Kill Reaction:

I2 + 2 S2O32- ==> S4O6

2- + 2 I- (Iodine Clock Reaction) ΔHrxn = ? kJ/mol

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http://www1.chem.leeds.ac.uk/delights/texts/expt_11.html

Chemicals to be used:

4.3 g potassium iodate (KIO3) 10 mL 1 M sulfuric acid (H2SO4) Deionized water 1.5 g malonic acid (HOOCCH2COOH) 0.4 g manganese sulfate monohydrate (MnSO4 . H2O) 30 mL of 30% hydrogen peroxide (H2O2) 0.1 g of soluble starch ~4 g sodium thiosulfate (Na2S2O3)

Chemicals produced:

ICH(CO2H)2

Oxygen (O2) Water (H2O)

Equipment to be used:

3 100 mL beakers Tongs 3 Graduated cylinders Heated stirring plate Magnetic stir bar Three 100 mL containers for mixture storage Scale 500 mL beaker Funnel Weigh Scale

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Attachment 2 - Drawing of the laboratory or pilot area

Provide a detailed drawing of the laboratory or pilot area in which the work will be performed. Include locations of the experimental equipment, safety equipment (including eyewash stations and safety showers, fire extinguishers, first aid kids, noting the date(s) of last inspection of these safety devices), Safety Data Sheet (MSDS) compilation, chemical storage, and evacuation route.


Attachment 3 – Normal Operations, Startup and Shutdown Procedures

Provide a step-wise procedure that describes in detail how the work will be performed. The procedure should begin and end with the equipment in the normal idle (inoperative) state.

Include a statement of the required PPE at the beginning of the procedure, and at every location in the procedure where the PPE requirements change.

Indicate where hazardous feedstock chemicals will be stored, how they will be transported to the location of the experimental work, how they will be transferred from storage vial into the experimental apparatus, and how they will be returned to storage.

Take into account those items for which you indicate “yes” on the NMSU Lab Hazard Assessment Checklist (link found on the department website “Safety” page).

Safety: Wear proper protective equipment including chemical resistant gloves, lab coat and safety glasses when preparing and performing this demonstration. 30% hydrogen peroxide is corrosive and a strong oxidizing agent, contact with skin and eyes must be avoided. Concentrated hydrogen peroxide can cause burns. KIO3 is an oxidizer. Malonic acid solution is moderately toxic and corrosive to eyes, skin and respiratory tract. Sulfuric acid is severely corrosive to eyes, skin and other tissue. Sulphuric acid can cause severe burns, when concentrated it is a powerful dehydrating agent and generates considerable heat when diluted with water. If spilled on to the skin, care must be exercised to avoid excessive heating when flushing with water. If you have an ice bath on hand use the water from that or you can quickly remove the bulk of the liquid with a dry cloth or tissue. Flush with plenty of water and then treat the area with sodium hydrogen carbonate (NaHCO3). Spills on the floor or bench should be neutralized with sodium hydrogen carbonate (NaHCO3) and rinsed thoroughly. The reaction produces iodine which is toxic by inhalation and irritating to eyes, skin, and respiratory tract. Perform the demonstration in a well-ventilated room.

Preparation: These should be prepared under a ventilation hood prior to the demonstration as the hydrogen peroxide loses its effectiveness over time.

1. Solution A: Prepare 100 mL of 9% H2O2 by diluting 30 mL of 30% H2O2 with 70 mL of deionized H2O. Pour into container for transport.

2. Solution B: Prepare an acidified 0.2 M KIO3 solution by adding 10 mL of 1.0 M H2SO4 to 80 mL of deionized water. Dissolve 4.3 g KIO3 in this solution and dilute to 100 mL. Pour into container for transport.

3. Solution C: Prepare starch solution by dissolving 0.1 g of soluble starch in 90 mL of boiling deionized water. When cool, add 1.5 g malonic acid, 0.4 g MnSO4•H2O, stir and dilute to 100 mL. Pour into container for transport.

Demonstration:

Add 100 mL of Solution A to a clean 500 mL beaker on the magnetic stirrer fitted with a stir bar. Next, add 100 mL of Solution B and adjust the stirring rate to produce a vortex in the mixture. Once complete, add 100 mL of Solution C and let reaction stir. Upon addition of the final solution, bubbles should appear. The solution will turn yellow then blue, then colorless. This


reaction will oscillate for 5-10 minutes with a period which initially lasts 15 seconds but will gradually lengthen. The reaction is complete when the solution remains blue-black.

Storage and Transportation:

The solutions are to be stored in sealed glass bottles and used at the time of demonstration. Storage over long periods is not recommended because the concentrated hydrogen peroxide will lose effectiveness over time. They can be transported in any container that does not allow them to break and spill.

Clean Up:

Neutralize the iodine by reducing it to iodide. Add ~4 g sodium thiosulfate to the mixture. Stir until the mixture becomes colorless. The reaction between iodine and thiosulfate is exothermic and the mixture may be hot. Once cool, the neutralized mixture may be washed down the drain with water.

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Attachment 4 -. Emergency Shutdown Procedure

Provide a step-wise procedure that describes how the equipment will be brought to a safe state in the event of an emergency. The description should include a detailed explanation of how to attend to potential medical emergencies that may result.

1. Heated stirring plate – Turn off the heat and turn of the stirrer.

2. Place all glass in an appropriate transportation storage area.

3. Neutralize the iodine by reducing it to iodide. Add ~4 g sodium thiosulfate to the mixture. Stir until the mixture becomes colorless. The reaction between iodine and thiosulfate is exothermic and the mixture may be hot. Once cool, the neutralized mixture may be washed down the drain with water.


Attachment 5 - Waste Management Procedure

Prepare a Waste Management Procedure that provides the exact nature and estimated volumes of all wastes to be generated in performing these experiments. Forward to EH&S Environmental Affairs Manager, Andrew Kaczmarek [email protected] for approval.

Attach a copy of the approval received from EH&S to this section of the ESP.

1.) Waste Chemical Waste – After the demonstration and the mixture is neutralized with sodium thiosulfate it can be disposed of down the drain to the city sewer. The drain should be washed thoroughly.

2.) KIO3 powder spill on weigh scale - Sweep up, then place into a suitable container for disposal.


mailto:[email protected]

Attachment 6 – Hazard Identification and Mitigation

Identify ALL HIGH hazards associated with the experiment. The analysis must consider

all sources of energy (electric, chemical, hydraulics, mechanical, compressed gases), extreme conditions of pressure or temperature (from flame or steam to cryogenics), chemical storage, housekeeping, fire, and/or biological hazards.

Examples of HIGH hazards to include (list not exhaustive):

substances that are highly reactive, radioactive, highly flammable, pyrophoric, highly toxic, mutagenic, teratogenic, carcinogenic, or have very low exposure limits,

high voltage, high RF, x-ray, laser (class 3b or 4), high temperatures, and high pressure or pressurizing vessels.

When in doubt about whether a substance represents a HIGH HAZARD, ask for assistance.

For each HIGH hazard (use the checklist as a guide to identifying these hazards, chme.nmsu.edu/files/2013/11/Lab-PPE-selection1.pdf), provide the following information:

1. description of the HIGH hazard;

2. operational and engineering controls that will be used (based on identified industry best-practices used in addressing this safety hazard);

3. required PPE (beyond minimum) when this HIGH hazard is present; and

4. special training (beyond minimum) that is necessary.

1.) Small volume of corrosive liquids - 30% hydrogen peroxide is corrosive and a strong oxidizing agent, contact with skin and eyes must be avoided. Concentrated hydrogen peroxide can cause burns. KIO3 is an oxidizer. Malonic acid solution is moderately toxic and corrosive to eyes, skin and respiratory tract. Sulfuric acid is severely corrosive to eyes, skin and other tissue. Sulphuric acid can cause severe burns, when concentrated it is a powerful dehydrating agent and generates considerable heat when diluted with water. If spilled on to the skin, care must be exercised to avoid excessive heating when flushing with water. If you have an ice bath on hand use the water from that or you can quickly remove the bulk of the liquid with a dry cloth or tissue. Flush with plenty of water and then treat the area with sodium hydrogen carbonate (NaHCO3). Use safety glasses, chemical-resistant gloves, and lab coat.2.) Working with toxic chemicals - The reaction produces iodine which is toxic by inhalation and irritating to eyes, skin, and respiratory tract. Perform the demonstration in a well-ventilated room.3.) Possible minor chemical spill cleanup - Spills on the floor or bench should be neutralized with sodium hydrogen carbonate (NaHCO3) and rinsed thoroughly. Sweep up (KIO3), then place into a suitable container for disposal. Use safety glasses, chemical-resistant gloves, and lab coat.


http://chme.nmsu.edu/files/2013/11/Lab-PPE-selection1.pdf

4.) Heated stir plate – Use caution in preparation of solutions on heated stir plate. May cause burns if skin comes in contact with hot plate. Use gloves and tongs when handling hot containers.

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Attachment 7 – Safety Data Sheets ( MSDS) for all chemicals used/generated in experiment

Material Safety Data SheetPotassium Iodate

ACC# 19445Section 1 - Chemical Product and Company Identification

MSDS Name: Potassium Iodate Catalog Numbers: S71980, S77550, S77550-1, P253 100, P253 500, P253-100, P253-500, P253100, P253500, S71980-1, S71980-2, S71980-3 Synonyms: Iodic Acid Potassium Salt. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887

Section 2 - Composition, Information on IngredientsCAS# Chemical Name Percent EINECS/ELINCS

7758-05-6 Potassium Iodate 100 231-831-9

Hazard Symbols: O Risk Phrases: 22 8

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: white. Danger! Strong oxidizer. Contact with other material may cause a fire. Can be explosive when exposed to heat or flames. May cause kidney damage. May cause central nervous system effects. May cause severe eye, skin and respiratory tract irritation with possible burns. Target Organs: Kidneys, central nervous system.

Potential Health Effects Eye: May cause eye irritation. May cause conjunctivitis. May cause permanent corneal opacification. Skin: May cause severe irritation and possible burns. Ingestion: May cause burns to the gastrointestinal tract. May cause nausea, vomiting, and diarrhea, possibly with blood. Inhalation: May cause acute pulmonary edema, asphyxia, chemical pneumonitis, and upper airway obstruction caused by edema. Chronic: Prolonged or repeated skin contact may cause irritation. Prolonged or repeated exposure may cause gastrointestinal irritation and kidney damage. Chronic ingestion may cause central nervous system failure. Effects may be delayed.


Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Do NOT use mouth-to-mouth resuscitation. Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Strong oxidizer. Contact with combustible materials may cause a fire. Use water spray to keep fire-exposed containers cool. Use water with caution and in flooding amounts. This material is an explosion hazard when exposed to heat, mechanical shock, or friction. Containers may explode when heated. Runoff to sewer may create fire or explosion hazard. Extinguishing Media: Contact professional fire-fighters immediately. Cool containers with flooding quantities of water until well after fire is out. For small fires, do NOT use dry chemicals, carbon dioxide, halon or foams. USE WATER ONLY. For large fires flood fire with water from a distance.

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with clothing and other combustible materials. Do not get on skin or in eyes. Avoid ingestion and inhalation. Avoid mechanical shock and friction. Storage: Keep away from heat, sparks, and flame. Do not store near combustible materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from reducing agents.

Section 8 - Exposure Controls, Personal Protection

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Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits

Chemical Name ACGIH NIOSH OSHA - Final PELsPotassium Iodate none listed none listed none listed

OSHA Vacated PELs: Potassium Iodate: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear a chemical apron. Wear appropriate clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties

Physical State: Solid Appearance: white Odor: odorless pH: Not available. Vapor Pressure: Not available. Vapor Density: Not available. Evaporation Rate:Not available. Viscosity: Not available. Boiling Point: 560 deg F Freezing/Melting Point:1040 deg F Autoignition Temperature: Not available. Flash Point: Not available. Decomposition Temperature:1040 deg F NFPA Rating: (estimated) Health: 2; Flammability: 0; Reactivity: 1 Explosion Limits, Lower:Not available. Upper: Not available. Solubility: Soluble in water Specific Gravity/Density:3.93 Molecular Formula:KIO3 Molecular Weight:214.001

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: High temperatures, incompatible materials, ignition sources, dust generation, combustible materials, reducing agents. Incompatibilities with Other Materials: Reducing agents.

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Hazardous Decomposition Products: Irritating and toxic fumes and gases, oxides of potassium, iodine. Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#: CAS# 7758-05-6: NN1350000 LD50/LC50:Not available.

Carcinogenicity:CAS# 7758-05-6: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No information found. Teratogenicity: No information found. Reproductive Effects: No information found. Neurotoxicity: No data available. Mutagenicity: No data available. Other Studies: No data available.

Section 12 - Ecological Information

No information available.Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT IATA RID/ADR IMO Canada TDG

Shipping Name:

OXIDIZING SOLID, N.O.S. (POTASSIUM IODATE)

OXIDIZING SUBSTANCES

NOS (POTASSIUM

IODATE)Hazard Class: 5.1 5.1(9.2)UN Number: UN1479 UN1479

Packing Group: II II

Section 15 - Regulatory Information

US FEDERAL

21

TSCA CAS# 7758-05-6 is listed on the TSCA inventory. Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List. Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)None of the chemicals in this material have an RQ. Section 302 (TPQ)None of the chemicals in this product have a TPQ. SARA CodesCAS # 7758-05-6: flammable. Section 313No chemicals are reportable under Section 313. Clean Air Act:This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA:None of the chemicals in this product are considered highly hazardous by OSHA. STATECAS# 7758-05-6 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:O Risk Phrases:R 22 Harmful if swallowed. R 8 Contact with combustible material may cause fire.

Safety Phrases:S 17 Keep away from combustible material.

WGK (Water Danger/Protection)CAS# 7758-05-6: 1 CanadaCAS# 7758-05-6 is listed on Canada's DSL List. CAS# 7758-05-6 is listed on Canada's DSL List. This product has a WHMIS classification of C, D2B. CAS# 7758-05-6 is not listed on Canada's Ingredient Disclosure List. Exposure Limits

22

Section 16 - Additional Information

MSDS Creation Date: 12/12/1997 Revision #4 Date: 8/02/2000 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

Material Safety Data SheetSulfuric Acid


MSDS Name: Sulfuric Acid Catalog Numbers: S71211SC, S71826, S79200, S80213, S80213-1, A298 212, A298212, A300 212, A300 225LB, A300 500, A300 612GAL, A300 700LB, A300212, A300225LB, A300500, A300612GAL, A300700LB, A300C 212, A300C212, A300C212001, A300C212002, A300C212003, A300C212004, A300C212005, A300C212006, A300C212007, A300C212008, A300C212009, A300C212010, A300C212LC, A300FP 500, A300FP500, A300J500, A300P 500, A300P500, A300S 212, A300S 500, A300S212, A300S212LC, A300S500, A300SI 212, A300SI212, A468-1, A468-250, A468-500, A4682, A484 212, A484212, A510-212, A510-500, A510SK212, AC3000S212002, MAR77018068, NC9466102, NC9499595, NC9755547, NC9825433, NC9826713, S71211, S71211MF, S71211MF*, S71211SCMF, S71211SCMF*, S79200MF, S79200MF* DHAZ, S79200MF*DHAZ, S79200SCMF, SA174 212, SA174 4, SA174212, SA1744, SA176 4, SA1764, SA196 500, SA196500 Synonyms: Hydrogen Sulfate; Oil of Vitriol; Vitriol Brown Oil; Matting Acid; Battery Acid; Sulphuric Acid. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887


7664-93-9 Sulfuric acid 95-98.0 231-639-5

Hazard Symbols: C Risk Phrases: 35 8


23

EMERGENCY OVERVIEW

Appearance: clear colorless - oily liquid. Danger! Corrosive. Causes eye and skin burns. May cause severe respiratory tract irritation with possible burns. May cause severe digestive tract irritation with possible burns. Cancer hazard. May cause fetal effects based upon animal studies. May cause kidney damage. May be fatal if inhaled. May cause lung damage. Hygroscopic. Strong oxidizer. Contact with other material may cause a fire. May cause severe eye, skin and respiratory tract irritation with possible burns. Target Organs: Kidneys, heart, lungs, respiratory system, cardiovascular system, teeth, eyes.

Potential Health Effects Eye: Causes severe eye burns. May cause irreversible eye injury. May cause conjunctivitis. May cause permanent corneal opacification. Skin: Causes skin burns. Continued contact can cause tissue necrosis. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color. Ingestion: May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause systemic toxicity with acidosis. Inhalation: May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Causes corrosive action on the mucous membranes. Chronic: Prolonged or repeated inhalation may cause kidney and lung damage. Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated inhalation may cause nosebleeds, nasal congestion, erosion of the teeth, perforation of the nasal septum, chest pain and bronchitis. Prolonged or repeated eye contact may cause conjunctivitis. May cause fetal effects. May cause cancer in humans. Effects may be delayed. Laboratory experiments have resulted in mutagenic effects. May cause ischemic heart lesions.


Eyes: Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes). Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes. Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Monitor arterial blood gases, chest x-ray, and pulmonary function tests if respiratory tract irritation or respiratory depression is evident. Treat dermal irritation or burns with standard topical therapy. Effects may be delayed. Do

24

NOT use sodium bicarbonate in an attempt to neutralize the acid. Antidote: Do NOT use oils or ointments in eye.


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Strong oxidizer. Contact with combustible materials may cause a fire. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Will react with water to form toxic and corrosive fumes. Contact with water can cause violent liberation of heat and splattering of the material. Some oxidizers may react explosively with hydrocarbons(fuel). Contact with metals may evolve flammable hydrogen gas. May accelerate burning if involved in a fire. Containers may explode when heated or if contaminated with water. Runoff from fire control or dilution water may cause pollution. Extinguishing Media: Do NOT use water directly on fire. Use carbon dioxide or dry chemical. Do NOT get water inside containers. Contact professional fire-fighters immediately. Cool containers with flooding quantities of water until well after fire is out.


General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Use water spray to reduce vapors, do not put water directly on leak, spill area or inside container. Cover with dry earth, dry sand, or other non-combustible material followed with plastic sheet to minimize spreading and contact with water. Keep combustibles (wood, paper, oil, etc.,) away from spilled material.


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Use only in a chemical fume hood. Discard contaminated shoes. Keep from contact with moist air and steam. Storage: Do not store near combustible materials. Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Corrosives area. Do not store near alkaline substances. Store protected from moisture.


Engineering Controls: Facilities storing or utilizing this material should be equipped

25

with an eyewash facility and a safety shower. Use only under a chemical fume hood. Exposure Limits

Chemical Name ACGIH NIOSH OSHA - Final PELs

Sulfuric acid (1 mg/m3) TWA; (3 mg/m3) STEL

1 mg/m3 TWA 15 mg/m3 IDLH 1 mg/m3 TWA

OSHA Vacated PELs: Sulfuric acid: 1 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.


Physical State: Liquid Appearance: clear colorless - oily liquid Odor: odorless pH: 0.3 (1N Solution) Vapor Pressure: 1 mm Hg @ 145.8 C Vapor Density: 3.38 Evaporation Rate:Slower than ether. Viscosity: 21 mPas @ 25 C Boiling Point: 340 deg C Freezing/Melting Point:10.35 deg C Autoignition Temperature: Not available. Flash Point: Not available. Decomposition Temperature:340 deg C NFPA Rating: (estimated) Health: 3; Flammability: 0; Reactivity: 2 Explosion Limits, Lower:Not available. Upper: Not available. Solubility: Soluble. Specific Gravity/Density:1.841 Molecular Formula:H2SO4 Molecular Weight:98.0716


Chemical Stability: Combines vigorously with water with the evolution of heat. Reported to have exploded when in a sealed container. This was most likely due to pressure of hydrogen by reduction of water. Conditions to Avoid: Incompatible materials, ignition sources, metals, excess heat, combustible materials, organic materials, reducing agents, exposure to moist air or water, oxidizers, amines, bases. Incompatibilities with Other Materials: Bases, strong dehydrating agents, organic materials, finely powdered metals, moisture, carbides, chlorates, cyanides (e.g. potassium cyanide, sodium cyanide), azides, fulminates, picrates, nitrates, alkali halides, zinc, iodides, permanganates, hydrogen peroxides, perchlorates,

26

nitromethane, phosphorus, nitrites, cyclopentadiene, cyclpentanone oxime, nitroaryl amines, lithium silicides, iron, mercuric nitride, benzene, potassium chlorates, steel, cesium acetylene carbide, trihydroxydiamino phosphate, phosphorus trioxide, reducing agents. Hazardous Decomposition Products: Oxides of sulfur, irritating and toxic fumes and gases. Hazardous Polymerization: Has not been reported.


RTECS#: CAS# 7664-93-9: WS5600000 LD50/LC50:CAS# 7664-93-9:Draize test, rabbit, eye: 250 ug Severe;Inhalation, mouse: LC50 = 320 mg/m3/2H;Inhalation, rat: LC50 = 510 mg/m3/2H;Oral, rat: LD50 = 2140 mg/kg;<br. Carcinogenicity:CAS# 7664-93-9: ACGIH: A2 - Suspected Human Carcinogen (contained in strong inorganic acid mists) OSHA: Select carcinogen IARC: Group 1 carcinogen Epidemiology: No data available. Teratogenicity: No data available. Reproductive Effects: No data available. Neurotoxicity: No data available. Mutagenicity: No data available. Other Studies: No data available.</br.


Ecotoxicity: Fish: Bluegill/Sunfish: 49 mg/L; 48Hr; TLm (tap water @ 20C)Fish: Bluegill/Sunfish: 24.5 ppm; 48Hr; TLm (fresh water)

Section 13 - Disposal Considerations




27

Shipping Name:

SULFURIC ACID

SULFURIC ACID

Hazard Class: 8 8(9.2)UN Number: UN1830 UN1830



US FEDERALTSCA CAS# 7664-93-9 is listed on the TSCA inventory. Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List. Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)CAS# 7664-93-9: final RQ = 1000 pounds (454 kg) Section 302 (TPQ)CAS# 7664-93-9: TPQ = 1000 pounds; RQ = 1000 pounds SARA CodesCAS # 7664-93-9: acute, chronic, reactive. Section 313This material contains Sulfuric acid (CAS# 7664-93-9, 95 98 0%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. Clean Air Act:This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:CAS# 7664-93-9 is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA:None of the chemicals in this product are considered highly hazardous by OSHA. STATECAS# 7664-93-9 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:C Risk Phrases:R 35 Causes severe burns. R 8 Contact with combustible material may cause

28

fire.

Safety Phrases:S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 30 Never add water to this product. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

WGK (Water Danger/Protection)CAS# 7664-93-9: 2 CanadaCAS# 7664-93-9 is listed on Canada's DSL List. CAS# 7664-93-9 is listed on Canada's DSL List. This product has a WHMIS classification of E, D1A. CAS# 7664-93-9 is listed on Canada's Ingredient Disclosure List. Exposure LimitsCAS# 7664-93-9: OEL-ARAB Republic of Egypt:TWA 1 mg/m3 OEL-AUSTRALIA:TWA 1 mg/m3 OEL-BELGIUM:TWA 1 mg/m3;STEL 3 mg/m3 OEL-CZECHOSLOVAKIA:TWA 1 mg/m3;STEL 2 mg/m3 OEL-DENMARK:TWA 1 mg/m3 OEL-FINLAND:TWA 1mg/m3;STEL 3 mg/m3;Skin OEL-FRANCE:TWA 1 mg/m3;STEL 3 mg/m3 OEL-GER MANY:TWA 1 mg/m3 OEL-HUNGARY:STEL 1 mg/m3 OEL-JAPAN:TWA 1 mg/m3 OEL-THE NETHERLANDS:TWA 1 mg/m3 OEL-THE PHILIPPINES:TWA 1 mg/m3 OEL-POLAND:TWA 1 mg/m3 OEL-RUSSIA:STEL 1 mg/m3;Skin OEL-SWEDEN:TWA 1 mg/m3;STEL 3 mg/m3 OEL-SWITZERLAND:TWA 1 mg/m3;STEL 2 mg/m3 OEL-THAILAND:TWA 1 mg/m3 OEL-TURKEY:TWA 1 mg/m3 OEL-UNITED KINGDOM:TWA 1 mg/m3 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV



Material Safety Data SheetMalonic Acid


MSDS Name: Malonic Acid Catalog Numbers: S80069, S80069A, A170 100, A170-100, A170100 Synonyms: Carboxyacetic Acid; Dicarboxymethane; Methanedicarboxylic Acid; Propanedioic Acid. Company Identification: Fisher Scientific

29

1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887


141-82-2 MALONIC ACID >99 205-503-0

Hazard Symbols: XN Risk Phrases: 22 36/37/38


EMERGENCY OVERVIEW

Appearance: white. May be harmful if swallowed. Warning! Causes eye and skin irritation. May cause digestive tract irritation. Causes respiratory tract irritation. Irritant. Target Organs: No data found.

Potential Health Effects Eye: Causes severe eye irritation and possible burns. May cause chemical conjunctivitis. Skin: Causes skin irritation. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. Inhalation: May cause severe irritation of the upper respiratory tract with pain, burns, and inflammation. Can produce delayed pulmonary edema. Chronic: Effects may be delayed.


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. Notes to Physician: Treat symptomatically and supportively.


30

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Use water spray, dry chemical, carbon dioxide, or appropriate foam.


General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.



Chemical Name ACGIH NIOSH OSHA - Final PELsMALONIC ACID none listed none listed none listed

OSHA Vacated PELs: MALONIC ACID: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

31


Physical State: Solid Appearance: white Odor: none reported pH: Acidic in solution. Vapor Pressure: Negligible. Vapor Density: Not available. Evaporation Rate:Negligible. Viscosity: Not available. Boiling Point: 284 deg F Freezing/Melting Point:276 deg F Autoignition Temperature: Not applicable. Flash Point: Not applicable. Decomposition Temperature:284 deg F NFPA Rating: (estimated) Health: 2; Flammability: 0; Reactivity: 0 Explosion Limits, Lower:Not available. Upper: Not available. Solubility: Completely soluble in water. Specific Gravity/Density:1.62 (water=1) Molecular Formula:C3H4O4 Molecular Weight:104.0256


Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, dust generation, excess heat. Incompatibilities with Other Materials: Oxidizing agents, reducing agents, bases. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported.


RTECS#: CAS# 141-82-2: OO0175000 LD50/LC50:CAS# 141-82-2:Draize test, rabbit, eye: 100 mg Severe;Draize test, rabbit, skin: 500 mg/24H Mild;Inhalation, rat: LC50 = >8900 mg/m3/1H;Oral, mouse: LD50 = 4 gm/kg;Oral, rat: LD50 = 1310 mg/kg;<br. Carcinogenicity:CAS# 141-82-2: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Neurotoxicity: No information available.

32

Mutagenicity: No information available. Other Studies: No data available.</br.






Shipping Name:

No information available.


Hazard Class:UN Number:

Packing Group:


US FEDERALTSCA CAS# 141-82-2 is listed on the TSCA inventory. Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List. Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)None of the chemicals in this material have an RQ. Section 302 (TPQ)None of the chemicals in this product have a TPQ. SARA CodesCAS # 141-82-2: acute. Section 313

33

No chemicals are reportable under Section 313. Clean Air Act:This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA:None of the chemicals in this product are considered highly hazardous by OSHA. STATECAS# 141-82-2 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:XN Risk Phrases:R 22 Harmful if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin.

Safety Phrases:S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 28 After contact with skin, wash immediately with...

WGK (Water Danger/Protection)CAS# 141-82-2: 1 CanadaCAS# 141-82-2 is listed on Canada's DSL List. CAS# 141-82-2 is listed on Canada's DSL List. This product has a WHMIS classification of D2B. CAS# 141-82-2 is not listed on Canada's Ingredient Disclosure List. Exposure Limits



Material Safety Data SheetManganese (II) Sulfate Monohydrate

34


MSDS Name: Manganese (II) Sulfate Monohydrate Catalog Numbers: S80061ACS, S80071-2, M113 3, M113 500, M113-3, M113-500, M1133, M113500, M114-12, M114-212, M114-500, M114212, M114500, M11512, M115212, M115500, NC9747671 Synonyms: Manganese(II) sulfate, monohydrate, manganous sulfate monohydrate Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887


10034-96-5 Manganese sulfate, monohydrate >98 unlisted

Hazard Symbols: XN Risk Phrases: 40/20/22


EMERGENCY OVERVIEW

Appearance: pink. Caution! May cause eye and skin irritation. May cause respiratory and digestive tract irritation. May cause central nervous system effects. Hygroscopic. Target Organs: Central nervous system.

Potential Health Effects Eye: May cause mild eye irritation. Skin: May cause skin irritation. Low hazard for usual industrial handling. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Inhalation: May cause respiratory tract irritation. Chronic: Chronic inhalation or ingestion may cause argyria characterized by blue-gray discoloration of the eyes, skin and mucous membrances. Chronic skin contact may cause permanent discoloration of the skin.


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing

35

contaminated clothing and shoes. Get medical aid if irritation develops or persists. Remove contaminated clothing and shoes. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Antidote: The use of Calcium disodium EDTA as a chelating agent should be determined by qualified medical personnel.


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Material will not burn. Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.


General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.


Handling: Wash hands before eating. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Storage: Store in a tightly closed container.


Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Exposure Limits

Chemical Name ACGIH NIOSH OSHA - Final PELsManganese sulfate,

monohydrate none listed none listed none listed

OSHA Vacated PELs: Manganese sulfate, monohydrate: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear impervious gloves. Clothing: Wear appropriate protective gloves and clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or

36

European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.


Physical State: Solid Appearance: pink Odor: odorless pH: Not available. Vapor Pressure: Not available. Vapor Density: Not available. Evaporation Rate:Not available. Viscosity: Not available. Boiling Point: 1562 deg F Freezing/Melting Point:1292 deg F Autoignition Temperature: Not available. Flash Point: Not available. Decomposition Temperature:Not available. NFPA Rating: (estimated) Health: 1; Flammability: 0; Reactivity: 0 Explosion Limits, Lower:Not available. Upper: Not available. Solubility: Completely soluble in water. Specific Gravity/Density:3.25 (water=1) Molecular Formula:MnSO4.H2O Molecular Weight:169.009


Chemical Stability: Stable. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Can react with strong acid, strong oxidizing agents, powdered metals; may react violently with hydrogen peroxide. Hazardous Decomposition Products: Carbon dioxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide, oxides of manganese. Hazardous Polymerization: Has not been reported.


RTECS#: CAS# 10034-96-5: OP0893500 LD50/LC50:Not available.

Carcinogenicity:CAS# 10034-96-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No data available. Teratogenicity: No data available. Reproductive Effects: No data available. Neurotoxicity: No data available. Mutagenicity: No data available. Other Studies: No data available.

37






Shipping Name:




Packing Group:


US FEDERALTSCA CAS# 10034-96-5 is not on the TSCA Inventory. It is a hydrate and exempt from TSCA Inventory requirements (40CFR720.3(u)(2)). Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List. Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)None of the chemicals in this material have an RQ. Section 302 (TPQ)None of the chemicals in this product have a TPQ. SARA CodesCAS # 10034-96-5: chronic. Section 313This material contains Manganese sulfate, monohydrate (listed as ** undefined **),

38

98%, (CAS# 10034-96-5) which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. Clean Air Act:This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA:None of the chemicals in this product are considered highly hazardous by OSHA. STATECAS# 10034-96-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:XN Risk Phrases:R 40/20/22 Harmful : possible risk of irreversible effects through inhalation and if swallowed.

Safety Phrases:

WGK (Water Danger/Protection)CAS# 10034-96-5: 1 CanadaCanada

None of the chemicals in this product are listed on the DSL or NDSL list. This product has a WHMIS classification of D2B. CAS# 10034-96-5 is not listed on Canada's Ingredient Disclosure List. Exposure LimitsCAS# 10034-96-5: OEL-AUSTRALIA:TWA 5 mg(Mn)/m3 JANUARY 1993 OEL-BELGIUM:TWA 5 mg(Mn)/m3 JANUARY 1993 OEL-CZECHOSLOVAKIA:TWA 2 mg(Mn)/m3;STEL 6 mg(Mn)/m3 JANUARY 1993 OEL-DENMARK:TWA 2.5 mg(Mn)/m3 JANUARY 1993 OEL-FINLAND:TWA 2.5 mg(Mn)/m3 JANUARY 1993 OEL-HUNGARY:TWA 0.3 mg(Mn)/m3;STEL 0.6 mg(Mn)/m3 JANUARY 1993 OEL-JAPAN:TWA 0.3 mg(Mn)/m3 JANUARY 1993 OEL-THE NETHERLANDS:TWA 1 mg(Mn)/m3 JANUARY 1993 OEL-POLAND:TWA 0.3 mg(Mn)/m3 JANUARY 1993 OEL-SWEDEN:TWA 1 mg(Mn)/m 3;STEL 2.5 mg(Mn)/m3 (resp. dust) OEL-SWEDEN:TWA 2.5 mg(Mn)/m3;STEL 5mg(Mn)/m3 (total dust) OEL-UNITED KINGDOM:TWA 5 mg(Mn)/m3 JANUARY 1 993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV


MSDS Creation Date: 9/02/1997 Revision #1 Date: 8/02/2000 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any

39

claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

Material Safety Data Sheet.Hydrogen Peroxide 30-50%


MSDS Name: .Hydrogen Peroxide 30-50% Catalog Numbers: AC9470941, S74876, S74876-1, S748761, S74879, S74882, H323-500, H323500, H325 100, H325 4, H325 500, H325-100, H325-30GAL, H325-4, H325-500, H325100, H32530GAL, H3254, H325500, H325500001, H327 500, H327-500, H327500, H327500LC, H341 500, H341-500, H341500, NC9839610, S748761MF, WESH325500, ZZH3253015 Synonyms: Carbamide Peroxide; Hydrogen Dioxide; Peroxide; Hydroperoxide; Urea Peroxide; Hydrogen Peroxide 100 Volumes. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887


7722-84-1 Hydrogen peroxide 30-50 231-765-07732-18-5 Water Balance 231-791-2

Hazard Symbols: O C Risk Phrases: 34 8


EMERGENCY OVERVIEW

Appearance: clear, colorless. Danger! Strong oxidizer. Contact with other material may cause a fire. Eye contact may result in permanent eye damage. May cause central nervous system effects. Causes eye and skin irritation and possible burns. Corrosive. May cause severe respiratory tract irritation with possible burns. May cause severe digestive tract irritation with possible burns. Mutagen. Light sensitive. May be harmful if swallowed. May cause blood abnormalities. Target Organs: Blood, central nervous system.

Potential Health Effects Eye: Contact with liquid is corrosive to the eyes and causes severe burns. Contact

40

with the eyes may cause corneal damage. Skin: Causes severe skin irritation and possible burns. May cause discoloration, erythema (redness), swelling, and the formation of papules and vesicles (blisters). Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Causes gastrointestinal tract burns. May cause vascular collapse and damage. May cause damage to the red blood cells. May cause difficulty in swallowing, stomach distension, possible cerebral swelling and death. Ingestion may result in irritation of the esophagus, bleeding of the stomach and ulcer formation. Inhalation: Causes chemical burns to the respiratory tract. May cause ulceration of nasal tissue, insomnia, nervous tremors with numb extremities, chemical pneumonia, unconsciousness, and death. At high concentrations, respiratory effects may include acute lung damage and delayed pulmonary edema. Chronic: Prolonged or repeated skin contact may cause dermatitis. Laboratory experiments have resulted in mutagenic effects. Repeated contact may cause corneal damage.


Eyes: Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes). Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes. Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Wash mouth out with water. Vomiting may occur spontaneously. If vomiting occurs and the victim is conscious, give water to further dilute the chemical. Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Treat symptomatically and supportively. Attempts at evacuating the stomach via emesis induction or gastric lavage should be avoided. In the event of severe distension of the stomach or esophagus due to gas formation, insertion of a gastric tube may be required. To treat corneal damage, careful ophthalmologic evaluation is recommended and the possibility of local corticosteroid therapy should be considered.


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Strong oxidizer. Contact with combustible materials may cause a fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Substance is noncombustible. Use water with caution and in flooding amounts. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Some oxidizers may react explosively with hydrocarbons(fuel). May decompose explosively when heated or involved in a fire. May accelerate burning if

41

involved in a fire. Extinguishing Media: Use water only! Do NOT use carbon dioxide. Do NOT use dry chemical. Do NOT get water inside containers. Contact professional fire-fighters immediately. Cool containers with flooding quantities of water until well after fire is out. For large fires, flood fire area with large quantities of water, while knocking down vapors with water fog.


General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Use water spray to disperse the gas/vapor. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as saw dust. Flush spill area with water. Provide ventilation. Do not get water inside containers. Keep combustibles (wood, paper, oil, etc.,) away from spilled material.


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Contents may develop pressure upon prolonged storage. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid contact with clothing and other combustible materials. Do not ingest or inhale. Store protected from light. Discard contaminated shoes. Unused chemicals should not be returned to the container. Rinse empty drums and containers thoroughly with water before discarding. Storage: Keep away from heat, sparks, and flame. Do not store near combustible materials. Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light. Keep away form alkalies, oxidizable materials, finely divided metals, alcohols, and permanganates. Store below 35°C. Store only in light-resistent containers fitted with a safety vent.


Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Exposure Limits


Hydrogen peroxide 1 ppm TWA1 ppm TWA; 1.4

mg/m3 TWA 75 ppm IDLH

1 ppm TWA; 1.4 mg/m3 TWA

Water none listed none listed none listed

OSHA Vacated PELs: Hydrogen peroxide: 1 ppm TWA; 1.4 mg/m3 TWA Water: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment

42

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR §1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.


Physical State: Liquid Appearance: clear, colorless Odor: slight acid odor pH: 3.3 (30% solution) Vapor Pressure: 23 mm Hg @ 30C Vapor Density: 1.10 Evaporation Rate:>1.0 (Butyl acetate=1) Viscosity: 1.25 cP Boiling Point: 108 deg C @ 760 mmHg Freezing/Melting Point:-33 deg C Autoignition Temperature: Noncombustible Flash Point: Noncombustible Decomposition Temperature:Not available. NFPA Rating: (estimated) Health: 3; Flammability: 0; Reactivity: 1 Explosion Limits, Lower:40 vol % Upper: 100 vol % Solubility: Miscible in water. Specific Gravity/Density:1.1-1.2 (30-50%) Molecular Formula:H2O2 Molecular Weight:34.0128


Chemical Stability: Decomposes slowly to release oxygen. Unstable when heated or contaminated with heavy metals, reducing agents, rust, dirt or organic materials. Stability is reduced when pH is above 4.0. Conditions to Avoid: Mechanical shock, incompatible materials, light, ignition sources, dust generation, excess heat, combustible materials, reducing agents, alkaline materials, strong oxidants, rust, dust, pH > 4.0. Incompatibilities with Other Materials: Strong oxidizing agents, strong reducing agents, acetic acid, acetic anhydride, alcohols, brass, copper, copper alloys, finely powdered metals, galvanized iron, hydrazine, iron, magnesium, nitric acid, sodium carbonate, potassium permanganate, cyanides (e.g. potassium cyanide, sodium cyanide), ethers (e.g. dioxane, furfuran, tetrahydrofuran (THF)), urea, chlorosulfonic acid, alkalies, lead, nitrogen compounds, triethylamine, silver, nickel, palladium, organic matter, charcoal, sodium borate, aniline, platinum, formic acid, cyclopentadiene, activated carbon, tert-butyl alcohol, hydrogen selenide, manganese dioxide, mercurous chloride, rust, ketones, carboxylic acids, glycerine, sodium fluoride, sodium pyrophosphate, soluble fuels (acetone, ethanol, glycerol), wood, wood, asbestos, hexavalent chromium compounds, salts of iron, copper, chromium, vanadium, tungsten, molybdeum, and platinum.

43

Hazardous Decomposition Products: Oxygen, hydrogen gas, water, heat, steam. Hazardous Polymerization: Will not occur.


RTECS#: CAS# 7722-84-1: MX0887000; MX0890000; MX0899000; MX0899500; MX0900000 CAS# 7732-18-5: ZC0110000 LD50/LC50:CAS# 7722-84-1:Inhalation, rat: LC50 = 2 gm/m3/4H;Oral, mouse: LD50 = 2 gm/kg;Oral, rabbit: LD50 = 820 mg/kg;Oral, rat: LD50 = 1518 mg/kg;Oral, rat: LD50 = 910 mg/kg;Oral, rat: LD50 = 376 mg/kg;Skin, rat: LD50 = 3 gm/kg;Skin, rat: LD50 = 4060 mg/kg;<br. CAS# 7732-18-5:Oral, rat: LD50 = >90 mL/kg;<br. Carcinogenicity:CAS# 7722-84-1: ACGIH: A3 - Animal Carcinogen IARC: Group 3 carcinogen CAS# 7732-18-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Neurotoxicity: No information available. Mutagenicity: CAS#: 7722-84-1 Mutation in Microorganisms: Salmonella typhimurium = 100 ug/plate.; Hyman, embryo = 50 umol/L.; Cytogenetic Analysis: Human, embryo = 20 umol/L. Mutation in Mammalian Somatic Cells: Hamster, lung = 1mmol/L. Other Studies: No data available.</br.</br.


Ecotoxicity: Fish: Carp: LC50 = 42 mg/L; 48 Hr; Unspecified Fathead Minnow: LC50 = 16.4 mg/L; 96 Hr; Fresh water Fathead Minnow: NOEC = 5 mg/L; 96 Hr; Fresh water flea Daphnia: EC50 = 2.4 mg/L; 48 Hr; Fresh water Channel catfish: LC50 = 37.4 mg/L; 96 Hr; Fresh water No data available. Environmental: Rain washout is expected due to condensation of hydrogen peroxide on contact with water droplets. In the atmosphere, indirect photooxidation is perdicted with a half-life of 10 to 20 hours. Non-significant evaporation and adsorption from water surfaces and soil/sediments is expected. Rapid and cosiderable aerobic biodegradation was determined with a half-life < 1 minute (biological treatment sludge) and 0.3 to 2 days (fresh water). Hydrogen peroxide is non-bioaccumulable.

44

Physical: No information available. Other: No information available.





Shipping Name:

HYDROGEN PEROXIDE, AQUEOUS SOLUTIONS 30%

HYDROGEN PEROXIDE

Hazard Class: 5.1 5.1(8)UN Number: UN2014 UN2014



US FEDERALTSCA CAS# 7722-84-1 is listed on the TSCA inventory. CAS# 7732-18-5 is listed on the TSCA inventory. Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List. Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)None of the chemicals in this material have an RQ. Section 302 (TPQ)CAS# 7722-84-1: concentration > 52%: TPQ = 1000 pounds; RQ = 1000 poun ds SARA CodesCAS # 7722-84-1: acute, flammable. Section 313No chemicals are reportable under Section 313. Clean Air Act:

45

This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA:CAS# 7722-84-1 is considered highly hazardous by OSHA. STATECAS# 7722-84-1 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts. CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:O C Risk Phrases:R 34 Causes burns. R 8 Contact with combustible material may cause fire.

Safety Phrases:S 28 After contact with skin, wash immediately with... S 3 Keep in a cool place. S 36/39 Wear suitable protective clothing and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

WGK (Water Danger/Protection)CAS# 7722-84-1: 0 CAS# 7732-18-5: No information available. CanadaCAS# 7722-84-1 is listed on Canada's DSL List. CAS# 7722-84-1 is listed on Canada's DSL List. CAS# 7732-18-5 is listed on Canada's DSL List. CAS# 7732-18-5 is listed on Canada's DSL List.

This product has a WHMIS classification of C, E, D2A. CAS# 7722-84-1 is listed on Canada's Ingredient Disclosure List. CAS# 7732-18-5 is not listed on Canada's Ingredient Disclosure List. Exposure LimitsCAS# 7722-84-1: OEL-AUSTRALIA:TWA 1 ppm (1.5 mg/m3) OEL-BELGIUM:TWA1 ppm (1.4 mg/m3) OEL-DENMARK:TWA 1 ppm (1.4 mg/m3) OEL-FINLAND:TWA 1 ppm (1.4 mg/m3);STEL 3 ppm (4.2 mg/m3) OEL-FRANCE:TWA 1 ppm (1.5 m g/m3) OEL-GERMANY:TWA 1 ppm (1.4 mg/m3) OEL-THE NETHERLANDS:TWA 1 ppm (1.4 mg/m3) OEL-THE PHILIPPINES:TWA 1 ppm (1.4 mg/m3) OEL-SWITZERLAND:TWA 1 ppm (1.4 mg/m3);STEL 2 ppm (2.8 mg/m3) OEL-TURKEY:TWA 1 ppm(1.4 mg/m3) OEL-UNITED KINGDOM:TWA 1 ppm (1.5 mg/m3);STEL 2 ppm (3 m g/m3)

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Material Safety Data SheetStarch, Soluble and Hydrolysed


MSDS Name: Starch, Soluble and Hydrolysed Catalog Numbers: S71202, S78931, S78931-1, S78931-2, S79015, S79016, S516-100, S516-500, S676-2 Synonyms: Corn starch; Potato starch: iodine indicator. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887


9005-25-8 Starch 100 232-679-6

Hazard Symbols: None listed. Risk Phrases: None listed.


EMERGENCY OVERVIEW

Appearance: white. Caution! May cause eye and skin irritation. May cause respiratory tract irritation. This is expected to be a low hazard for usual industrial handling. Target Organs: None.

Potential Health Effects Eye: May cause eye irritation.

47

Skin: May cause mild skin irritation. Low hazard for usual industrial handling. Ingestion: Low hazard for usual industrial handling. Inhalation: May cause respiratory tract irritation. Low hazard for usual industrial handling. Chronic: No information found.


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid. Skin: Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid if irritation or symptoms occur. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Notes to Physician: No specific antidote exists. Treat symptomatically and supportively.


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.


General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.


Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Storage: Store in a cool, dry, well-ventilated area away from incompatible substances.


Engineering Controls: Use adequate general or local exhaust ventilation to keep

48

airborne concentrations below the permissible exposure limits. Exposure Limits


Starch 10 mg/m3 TWAtotal: 10 mg/m3 TWA;

respirable dust: 5 mg/m3 TWA

15 mg/m3 TWA (total dust); 5 mg/m3 TWA (respirable fraction)

OSHA Vacated PELs: Starch: total dust: 15 mg/m3 TWA; respirable fraction: 5 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.


Physical State: Solid Appearance: white Odor: odorless pH: 5 - 7 (2% solution) Vapor Pressure: Negligible. Vapor Density: Not available. Evaporation Rate:negligible Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point:Not available. Autoignition Temperature: Not available. Flash Point: Not applicable. Decomposition Temperature:Not available. NFPA Rating: (estimated) Health: 1; Flammability: 1; Reactivity: 0 Explosion Limits, Lower:Not available. Upper: Not available. Solubility: soluble in boiling water Specific Gravity/Density:1.5 Molecular Formula:C6H10O5x Molecular Weight:varies


Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: High temperatures, dust generation. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported.


49

RTECS#: CAS# 9005-25-8: GM5090000 LD50/LC50:Not available.

Carcinogenicity:CAS# 9005-25-8: ACGIH: A4 - Not Classifiable as a Human Carcinogen Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Neurotoxicity: No information available. Mutagenicity: Please refer to RTECS# GM5090000 for specific information. Other Studies: None.


Ecotoxicity: No data available. No information available. Environmental: No information reported. Physical: No information available. Other: No information available.





Shipping Name:




Packing Group:


US FEDERALTSCA

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CAS# 9005-25-8 is listed on the TSCA inventory. Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List. Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)None of the chemicals in this material have an RQ. Section 302 (TPQ)None of the chemicals in this product have a TPQ. Section 313No chemicals are reportable under Section 313. Clean Air Act:This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA:None of the chemicals in this product are considered highly hazardous by OSHA. STATECAS# 9005-25-8 can be found on the following state right to know lists: Pennsylvania, Minnesota, Massachusetts. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:Not available. Risk Phrases:

Safety Phrases:

WGK (Water Danger/Protection)CAS# 9005-25-8: 0 CanadaCAS# 9005-25-8 is listed on Canada's DSL List. CAS# 9005-25-8 is listed on Canada's DSL List. This product has a WHMIS classification of Not controlled.. CAS# 9005-25-8 is not listed on Canada's Ingredient Disclosure List. Exposure LimitsCAS# 9005-25-8: OEL-AUSTRALIA:TWA 10 mg/m3 OEL-BELGIUM:TWA 10 mg/m3OEL-SWITZERLAND:TWA 6 mg/m3 OEL-UNITED KINGDOM:TWA 10 mg/m3 (total dust) JAN9 OEL-UNITED KINGDOM:TWA 5 mg/m3 (resp. dust) OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV


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Material Safety Data SheetSodium Thiosulfate Pentahydrate


MSDS Name: Sodium Thiosulfate Pentahydrate Catalog Numbers: BW13680-03, BW13680-04, BW13680-05, BW13680-06, BW13680-20, NC9503498, NC9629890, NC9671016, S445-10, S445-3, S445-50, S445-500, S474-12, S474-3, S474-500, S78930, XXS445100KG, XXS47450KG Synonyms: Sodium Hyposulfite; Disodium Salt Pentahydrate; Disodium Thiosulfate Pentahydrate. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887


10102-17-7 Sodium Thiosulfate, Pentahydrate 100 unlisted

Hazard Symbols: None listed. Risk Phrases: None listed.


EMERGENCY OVERVIEW

Appearance: colorless to white. Caution! May cause eye and skin irritation. Hygroscopic. The toxicological properties of this material have not been fully investigated. May cause respiratory and digestive tract irritation. Target Organs: No data found.

Potential Health Effects Eye: May cause eye irritation.

52

Skin: Prolonged and/or repeated contact may cause irritation and/or dermatitis. Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. Low hazard for usual industrial handling. The toxicological properties of this substance have not been fully investigated. Chronic: No information found.


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively.


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.


General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.


Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid prolonged or repeated contact with skin. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Keep from contact with oxidizing

53

materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids. Store protected from moisture.



Chemical Name ACGIH NIOSH OSHA - Final PELsSodium Thiosulfate,

Pentahydrate none listed none listed none listed

OSHA Vacated PELs: Sodium Thiosulfate, Pentahydrate: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR §1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.


Physical State: Solid Appearance: colorless to white Odor: odorless pH: Not available. Vapor Pressure: Not available. Vapor Density: Not available. Evaporation Rate:Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point:48.5 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Decomposition Temperature:> 45 deg C NFPA Rating: (estimated) Health: 1; Flammability: 0; Reactivity: 0 Explosion Limits, Lower:Not available. Upper: Not available. Solubility: 680 G/L WATER (20°C) Specific Gravity/Density:1.7290g/cm3 Molecular Formula:Na2O3S2.5H2O Molecular Weight:248.18


Chemical Stability: Stable.

54

Conditions to Avoid: Incompatible materials, acids, strong oxidants, exposure to moist air or water. Incompatibilities with Other Materials: Moisture, strong acids, strong bases, strong oxidizing agents. Hazardous Decomposition Products: Irritating and toxic fumes and gases, hydrogen sulfide, sodium oxide. Hazardous Polymerization: Has not been reported.


RTECS#: CAS# 10102-17-7: WE6660000 LD50/LC50:Not available.

Carcinogenicity:CAS# 10102-17-7: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Neurotoxicity: No information available. Mutagenicity: No information available. Other Studies: See actual entry in RTECS for complete information.






Shipping Name:




Packing Group:


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US FEDERALTSCA CAS# 10102-17-7 is not on the TSCA Inventory. It is a hydrate and exempt from TSCA Inventory requirements (40CFR720.3(u)(2)). Health & Safety Reporting ListNone of the chemicals are on the Health & Safety Reporting List. Chemical Test RulesNone of the chemicals in this product are under a Chemical Test Rule. Section 12bNone of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use RuleNone of the chemicals in this material have a SNUR under TSCA. SARA

Section 302 (RQ)None of the chemicals in this material have an RQ. Section 302 (TPQ)None of the chemicals in this product have a TPQ. Section 313No chemicals are reportable under Section 313. Clean Air Act:This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act:None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA:None of the chemicals in this product are considered highly hazardous by OSHA. STATECAS# 10102-17-7 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International RegulationsEuropean Labeling in Accordance with EC DirectivesHazard Symbols:Not available. Risk Phrases:

Safety Phrases:S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S 28A After contact with skin, wash immediately with plenty of water.

WGK (Water Danger/Protection)CAS# 10102-17-7: 0 CanadaCanada

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None of the chemicals in this product are listed on the DSL or NDSL list. This product has a WHMIS classification of D2B. CAS# 10102-17-7 is not listed on Canada's Ingredient Disclosure List. Exposure Limits



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