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©2017 | www.agribodytech.com 1
Expanding Global Food Supply by Significantly
Increasing Crop Yields Using Patented Gene Technology
Jerry Feitelson, Ph.D., Co-Founder & CEO | [email protected] | (858) 349-3603
©2017 | www.agribodytech.com 2
THE
PROBLEM
• YIELD: Highest value trait to farmers
Conventional breeding reaching yield limits
• Tens of $Billions in crop loss caused by:
Post-harvest senescence
Disease (bacterial and fungal pathogens)
Stress (drought, low nutrients, salt, cold, heat)
3
OURDISRUPTIVESOLUTION
License or co-develop
proprietary Genome Edited seeds
with innovative seed companies in
forage, row or specialty crops
having
ULTRA HIGH YIELD &
STRESS RESISTANCE. -- Avoid GMO controversies --
©2017 | www.agribodytech.com 4
Hypusine
eIF-5ADHS
How? Genetically modify a biological switchThe eIF-5A/DHS hypusination pathway promotes either cell growth/division or cell death (apoptosis)
−Lysine
eIF-5A
Cell Growth/
Division
Cell
Apoptosis
• Increased biomass and seed yield
• Enhanced tolerance to stress & disease
+
©2017 | www.agribodytech.com 55
Market Opportunity2014 Crop (not Seed) Production: $23.5 Billion
$0.0
$1.0
$2.0
$3.0
$4.0
$5.0
$6.0
$7.0
$8.0
$9.0
Hay & Alfalfa Cotton Sugarbeets Canola Potatoes Rice Sorghum
33%
2014 U.S. Production (Bil)
82%
95%
87%
<5%
<5%
<5%
% GM Adoption
Bil
©2017 | www.agribodytech.com 66
• Broad Coverage
− 16 issued US Patents + 5 published US Patent Applications
− Foreign counterparts in several countries
− New applications for genome editing of DHS
− CRISPR license from Benson Hill Biosystems
• Matter & Methods claims
− eIF-5A overexpression has important phenotypes
• Higher seed & biomass yields
• Tolerance to abiotic stresses
− DHS knock-downs have clear phenotypes
• Delayed senescence
• Larger leaves
• Higher seed yields
• Stress tolerance
Strong IP Portfolio
7©2017 | www.agribodytech.com
1. Co-development started with 3rd largest
alfalfa seed company
2. License or Co-develop with seed companies in
12 other targeted crops (@ 2-3/yr)
− 3 crops between Seed & Series A rounds
3. Generate revenue from:
− Licensees:
o Tech Access Fees ($50-150K)
o Benchmark Payments ($2Mil)
o Royalties (5%)
− Co-Development Partners:
o Sales of partially-owned seeds (25 – 33%)
Business Model / Sales
$Partner.
License / Co-Develop.
Generate Revenue.
8©2017 | www.agribodytech.com
Single transgenes − Rare to boost yields >10% in greenhouse
− Few successful field trials
− Higher photosynthetic efficiency / C3 → C4
− Candidates for stressT
CompetitionMajor Ag Biotech / Ag Chem Companies Small- & Mid-size Companies
Agribody
TechnologiesEvoGene
Arcadia
BiosciencesCeres
Kapyon/
ZeaKal
Yield10
BioscienceKaiima
Improved
YieldX X X X X X X
Biotic
Stress
Tolerance
Bacteria,
Fungi
Nematode,
Fungi,
Insect,
Aphids
Fungi
Abiotic
Stress
Tolerance
Drought,
Crowding,
Low Nutrient
Drought
Drought,
Nitrogen
Efficiency,
Salt
Drought,
Poor SoilsDrought
Enhanced
Shelf Life
Tomato,
Banana,
Carnation
TILLING in
Tomato
Public, VC
or PrivateStart-Up NYSE NASDAQ NASDAQ VC
VC /
NASDAQVC
Major Ag Biotech / Ag Chem Companies
− GM traits for increasing yields indirect: insectR / herbicideT
− Extensive R&D on pathogen and abiotic stress resistance
− Potential acquirer
©2017 | www.agribodytech.com 99
ATI Executive Team
Paul Kreutz
Corporate Counsel
• Represented many VC firms
• Counsels & helps structure
growth-oriented
entrepreneurial enterprises
• B.A. (Yale), LL.B. (Stanford)
Jerry Feitelson, Ph.D.
CEO / Co-Founder
• >30 years R&D, IP,
Licensing & Bus Dev
experience
• Managed $10Mil royalties;
Negotiated $7Mil license
• Patented B.t.
genes/proteins lead to
$850Mil valuation
• B.S. (MIT), Ph.D. (Stanford)
John Thompson, Ph.D.
Chief Scientist / Co-Founder
• U. of Waterloo (Professor
Emeritus, Associate VP)
• Invented eIF-5A/DHS
technology
• B.S. (Toronto), Ph.D.
(Alberta), Fellow of Royal
Society of Canada
Jim Goode
Acting CFO
• 35 years managing financial/
admin functions of high-tech,
biotech and start-ups
• Raised >$100Mil
• MBA (UCLA), CPA (Arthur
Young)
©2017 | www.agribodytech.com 1010
ATI Consultants / Advisors
Alan Bennett, Ph.D.
Chair, SAB
• UC-Davis (Distinguished
Professor of Plant Science)
• Transformed/characterized
elite alfalfa with eIF-5A
• Runs advanced genetics lab
• B.S. (UC-Davis), Ph.D.
(Cornell)
Jerry Caulder, Ph.D.
Advisor
• Known as the “Father of
Agricultural Biotechnology”
• 15 years with Monsanto; as
CEO, built $1.2Bil valuation
• Lead 2 other companies,
Chair of Athenix, sold for
$400Mil. Founded Finistere
Ventures
• B.S. (SE Missouri State U.),
Ph.D. (U. Missouri)
Vaughn Smider, M.D., Ph.D.
Advisor
• CSO of Sevion Therapeutics,
Founder/President of precursor
company, Fabrus.
• Associate Professor at The
Scripps Research Institute
• Leadership Council for
American Cancer Society
• B.A (Hiram College), M.D. &
Ph.D. (Stanford U.)
Craig Williams
Field Trials / Regulatory
• 25 years experience
managing seed companies
• Knowledgeable in seed
business operations,
regulatory affairs, field
trials, M&A due diligence
• B.S. (Bradley U.)
©2017 | www.agribodytech.com 11
Opportunity for the Investor
• Seed round up to $950K in form of Convertible Notes with very favorable terms:
− Convertible into Series A round at 35% conversion discounts
− Annual 7% simple interest
− The Yield Lab & Dr. Feitelson lead investors
− Conversion pre-money valuation safeguards
• Goal for Preferred Stock Series A round of $3-5Mil (est.)
− Essentially plain vanilla
− Down round anti-dilution & participating upon dissolution
12©2017 | www.agribodytech.com
Acquisition expected in 5 - 6 years
Strategic Trade Sale
• Every license/JV deal (forage, row, specialty
seed company) could generate a buyer
Private Equity
• Trait consolidation opportunities for yield
improvement
Goal:
Raise $1M Seed + $3-5M Series A over 2 yrs
↓>$60M Exit (15x cash-on-cash return)
Exit Strategy
Successful ag biotech platform exits:
• AgriQuest ($450M Sale/Bayer)
• DeVGeN ($523M Sale/Syngenta)
• Athenix ($400M Sale/Bayer)
• Divergence ($71M Sale/Monsanto)
• Ceres ($344M IPO)
• Evogene ($389M IPO)
©2017 | www.agribodytech.com 1313
Summary
Join ATI in building
value by licensing &
co-developing ultra-
high yield, stress-
resistant crops with
established seed
companies
• CEO & Management TeamAg biotech entrepreneurs experienced,
resourceful, ethical
• Proof of Efficacy
• Broad IP
• Started alfalfa co-development
project & potato license
• License to Genome Editing & rapid
commercialization path
THANK YOU!Jerry Feitelson, Ph.D., Co-Founder & CEO
[email protected] | (858) 349-3603 | www.agribodytech.com