examples of secondary metabolites - durham university · examples of secondary metabolites name...
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Examples of Secondary Metabolites
Name Chemical Structure Species UsesMorphine
HN
H
HO
O
HO Papaversomniferum
(Poppy)
Pain control
Digitoxin O
OH
O
OC18H31O9
Digitalispurpurea
(Foxglove)
Treatment ofcongestive heartfailure and tocontrolventricular rate
Salicylic acid O OH
OH
Salix sp.
(Willow)
AnalgesicAnti-inflammatory
Pyrethrin I
O
O
O
Compositaefamily
(IncludingChrysanthemumand Pyrethrumpulchrum)
Insecticide
Taxol
HO
O
O OH
OAcOH
AcOO
HO
NH
O
O
O
Taxusbrevifolia
(Pacific Yew)
Anticancer agent
TetrodotoxinHN
NH
OO
OH
HO
OH
OHHO
H2N
OH
Lagocephaluslagocephalus
(Puffer fish)
Poison
Penicillin
N
S
CO2O
HN
O
Penicillium sp. Antibiotic
Lysergic acid
HN
N
H
O OH Claviceps sp.
(Ergot)
Poison
MuscarineO
HO
N
OHH3C
Amanitamuscaria
(Fly agaric)
Poison
Parasympathomi-metic
Lovastatin
O
OHO
H3C
O
O
H
Aspergillusterreus
Lowering ofCholesterol
Bleomycin(bleocin)
HN
O NH2
NH2
NH2
ON N
H2NO
HNNH
HOHN
NH
O
H
OH
N
S
S
N NH
O
HO
H
O
HO
HNH
N
O O
O
OH
OH
HO
OH
OHOH
O
O NH2
SStreptomycesverticillus
Antitumourantibiotic
Vancomycin
O
O
O
O
OH
HOHO
O
O
HOH2N
Cl
OH
O
HN
NH
ONHMe
NH
O
NH2
O
HN
O
HO
NH
O
NH
HO2C
O
OHOH
Cl
Nocardiaorientalis
(actinomyceteformerlyknown asStreptomycesorientalis)
Antibiotic