eval 6970: meta-analysis effect sizes and precision: part i dr. chris l. s. coryn spring 2011

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EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

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Page 1: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

EVAL 6970: Meta-AnalysisEffect Sizes and Precision:Part I

Dr. Chris L. S. CorynSpring 2011

Page 2: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

Agenda

β€’ Effect sizes based on meansβ€’ Review questionsβ€’ In-class activity

Page 3: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

Note

β€’ Statistical notation varies widely for the topics covered today and in future lectures

β€’ By convention (and for consistency), we will predominately use Borenstein, Hedges, Higgins, and Rothstein’s (2010) notation

Page 4: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

The Apples and Oranges Argument: Both are Fruits

There is a useful analogy between including different outcome measures in a meta-analysis, the common factor model, multiple-operationism, and concept-to-operation correspondence

Page 5: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

Effect Sizes

Page 6: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

Raw Mean Difference, D

β€’ The raw (unstandardized) mean difference can be used on a meaningful outcome measure (e.g. blood pressure) and when all studies use the same measure

β€’ The population mean difference is defined as

βˆ†=πœ‡1βˆ’πœ‡2

Page 7: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

D from Independent Groups

β€’ The mean difference from studies using two independent groups (e.g., treatment and control) can be estimated from the sample group means and as

𝐷=𝑋 1βˆ’π‘‹ 2

Page 8: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

D from Independent Groups

β€’ Assuming (as is assumed for most parametric statistics) the variance of D is

β€’ where

𝑉 𝐷=𝑛1+𝑛2𝑛1𝑛2

π‘†π‘π‘œπ‘œπ‘™π‘’π‘‘2

π‘†π‘π‘œπ‘œπ‘™π‘’π‘‘=√ (𝑛1βˆ’1 )𝑆12+ (𝑛2βˆ’1 )𝑆2

2

𝑛1+𝑛2βˆ’2

Page 9: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

D from Independent Groups

β€’ Assuming the variance of D is

β€’ For both and the standard error of D is

+

𝑆𝐸𝐷=βˆšπ‘‰ 𝐷

Page 10: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

D from Dependent Groups

β€’ When groups are dependent (e.g., matched pairs designs or pretest-posttest designs) then D is the difference score for each pair

𝐷=π‘‹π‘‘π‘–π‘“π‘“βˆ¨π·=𝑋 1βˆ’π‘‹ 2

Page 11: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

D from Dependent Groups

β€’ Where the variance is

β€’ Where n is the number of pairs, and

𝑉 𝐷=𝑆𝑑𝑖𝑓𝑓2  π‘›

𝑆𝐸𝐷=βˆšπ‘‰ 𝐷

Page 12: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

D from Dependent Groups

β€’ If must be computed

β€’ Where r is the correlation between pairs

β€’ If then

𝑆𝑑𝑖𝑓𝑓=√2Γ—π‘†π‘π‘œπ‘œπ‘™π‘’π‘‘2 (1βˆ’π‘Ÿ)

𝑆𝑑𝑖𝑓𝑓=βˆšπ‘†12+𝑆22βˆ’2Γ—π‘Ÿ ×𝑆1×𝑆2

Page 13: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

Standardized Mean Difference, d and g

β€’ Assuming (as is the case for most parametric statistics) the standardized mean difference population parameter is defined as

𝛿=πœ‡1βˆ’πœ‡2𝜎

Page 14: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Independent Groups

β€’ The standardized mean difference () from independent groups (e.g., treatment and control) can be estimated from the sample group means and as

𝑑=𝑋 1βˆ’π‘‹ 2

𝑆 h𝑀𝑖𝑑 𝑖𝑛

Page 15: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Independent Groups

β€’ Where is the within-groups standard deviation, pooled across groups

𝑆 h𝑀𝑖𝑑 𝑖𝑛=√ (𝑛1βˆ’1 )𝑆12+(𝑛2βˆ’1)𝑆2

2

𝑛1+𝑛2βˆ’2

Page 16: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Independent Groups

β€’ Where the variance is

β€’ And the standard error is

𝑉 𝑑=𝑛1+𝑛2𝑛1𝑛2

+ 𝑑2

2(𝑛1+𝑛2)

𝑆𝐸𝑑=βˆšπ‘‰ 𝑑

Page 17: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Independent Groups

β€’ In small samples (N < 20), d overestimates and this bias can be reduced by converting d to Hedges’ g using the correction factor J, where

β€’ For two independent groups

𝐽=1βˆ’3

4𝑑𝑓 βˆ’1

𝑑𝑓=𝑛1+𝑛2βˆ’2

Page 18: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Independent Groups

β€’ Using the correction factor J, Hedges’ g is calculated as

β€’ With

β€’ And

𝑔= 𝐽×𝑑

𝑉 𝑔= 𝐽 2×𝑉 𝑑

𝑆𝐸𝑔=βˆšπ‘‰ 𝑔

Page 19: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Dependent Groups

β€’ When groups are dependent (e.g., matched pairs designs or pretest-posttest designs) then d is the difference score for each pair

𝑑=π‘Œ 𝑑𝑖𝑓𝑓

𝑆 h𝑀𝑖𝑑 𝑖𝑛

=π‘Œ 1βˆ’π‘Œ 2

𝑆 h𝑀𝑖𝑑 𝑖𝑛

Page 20: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Dependent Groups

β€’ Where is

𝑆 h𝑀𝑖𝑑 𝑖𝑛=𝑆𝑑𝑖𝑓𝑓

√2(1βˆ’π‘Ÿ )

Page 21: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Dependent Groups

β€’ Where the variance is

β€’ Where n is the number of pairs, and

𝑉 𝑑=( 1𝑛+𝑑2

2𝑛 )2(1βˆ’π‘Ÿ )

𝑆𝐸𝐷=βˆšπ‘‰ 𝑑

Page 22: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Dependent Groups

β€’ If must be computed

β€’ Where r is the correlation between pairs

β€’ If then

𝑆𝑑𝑖𝑓𝑓=√2Γ—π‘†π‘π‘œπ‘œπ‘™π‘’π‘‘2 (1βˆ’π‘Ÿ)

𝑆𝑑𝑖𝑓𝑓=βˆšπ‘†12+𝑆22βˆ’2Γ—π‘Ÿ ×𝑆1×𝑆2

Page 23: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Dependent Groups

β€’ In small samples (N < 20), d overestimates and this bias can be reduced by converting d to Hedges’ g using the correction factor J, where

β€’ Where, in dependent groups

𝐽=1βˆ’3

4𝑑𝑓 βˆ’1

𝑑𝑓=π‘›βˆ’1

Page 24: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

d and g from Dependent Groups

β€’ Using the correction factor J, Hedges’ g is calculated as

β€’ With

β€’ And

𝑔= 𝐽×𝑑

𝑉 𝑔= 𝐽 2×𝑉 𝑑

𝑆𝐸𝑔=βˆšπ‘‰ 𝑔

Page 25: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

Effect Direction

β€’ For all designs the direction of the effect ( or ) is arbitrary, except that the same convention must be applied to all studies in a meta-analysis (e.g., a positive difference indicates that the treated group did better than the control group)

Page 26: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

Review Questions

1. When is it appropriate to use D?2. When is it appropriate to use d?3. When is it appropriate to use g?

Page 27: EVAL 6970: Meta-Analysis Effect Sizes and Precision: Part I Dr. Chris L. S. Coryn Spring 2011

Today’s In-Class Activity

β€’ Individually, or in your working groups, download β€œData Sets 1-6 XLSX” from the course Website– Calculate the appropriate effects sizes,

standard deviations, variances, and standard errors for Data Sets 1, 2, 3, and 4

– Be certain to save your work as we will use these data again