environmental risk assessment of engineered nanomaterials

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Environmental Risk Assessment of Engineered Nanomaterials Katerina Dontsova, Elizabeth Ferguson, Al Kennedy, Jerry Miller, Mo Qasim, Chuck Weiss, Jeffery Steevens Jeffery Steevens (lead) Email: [email protected] Environmental Laboratory and Geotechnical and Structures Laboratory US Army Engineer Research and Development Center

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Nanomaterials Risk Assessment Meet environmental sustainability objectives by identifying and quantifying the environmental attributes of nanomaterials. Sources of nanomaterials? Fate and transport mechanisms? Likely exposure scenarios? Biological effects resulting from exposure? Proactively support the development and implementation of nanotechnology. Must include milestones and completion dates per task as given in P2. Format is flexible, can use Excel table or Microsoft Project (example above). Gant Chart format is preferred (tie to P2 activity). Describe the project plan in detail. Use this chart to explain how you will execute the project. Provide an explanation of key project management and scientific activities that you will execute. Discuss key milestones and scheduling of deliverables. A discussion of how you will handle (analyze/evaluate) data is mandatory – i.e., what is your statistical design. Media Primary Pathway Receptor Secondary Material Conceptual model

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Page 1: Environmental Risk Assessment of Engineered Nanomaterials

Environmental Risk Assessment of Engineered Nanomaterials

Katerina Dontsova, Elizabeth Ferguson, Al Kennedy, Jerry Miller, Mo Qasim, Chuck Weiss, Jeffery Steevens

Jeffery Steevens (lead)Email: [email protected]

Environmental Laboratory and Geotechnical and Structures Laboratory

US Army Engineer Research and Development Center

Page 2: Environmental Risk Assessment of Engineered Nanomaterials

Nanomaterials Risk Assessment• Meet environmental sustainability objectives by

identifying and quantifying the environmental attributes of nanomaterials.– Sources of nanomaterials?– Fate and transport mechanisms?– Likely exposure scenarios?– Biological effects resulting from exposure?

• Proactively support the development and implementation of nanotechnology.

Media PrimaryPathway

PrimaryReceptor

Secondary Pathway

SecondaryReceptor

MaterialConceptual model

Page 3: Environmental Risk Assessment of Engineered Nanomaterials

Conceptual Model1. Sources 2. Media and

Transport Processes3. Exposure Pathways

and Receptors

Benthic Invertebrates

Aquatic Invertebrates

Fish

Terrestrial Vertebrates

Terrestrial Invertebrates

Sediment

Fish

Air

Water

Soil

Sorption / desorption

Engineered Nanostructures

Engineered Nanodevices

Reaction Intermediates

Production Waste

Product Degradation

Settling / suspension

Settling / suspension

Aggregation/Degradation

Degradation

Degradation

Aggregation/UV Degradation

Contact, Ingestion

Ingestion

Inhalation

Ingestion

Contac

tIng

estio

n

Product use, SpillsIntentional application,

disposalIn

gest

ion

ContactIngestion

ContactIngestion

Cont

act

Inge

stio

n

Contact

Ingestion

Ingestion

IngestionContact

Ingestio

n

Page 4: Environmental Risk Assessment of Engineered Nanomaterials

ERDC Research Efforts1. Relevant Vectors for Exposure (2 yr):Focus: Role of functionalization on the availability and toxicity of CNTUnique:1) CNT Only (PEG, NH3, COOH)2) Aquatic toxicity

2. Nanomaterial Structure Affect Biota? (2 yr): Focus: Biological effects of different nanomaterialsUnique:1) CNT, Fullerene, Metal Oxide, Reaction intermediates2) Measures of bioavailability/Toxicity

3. Nanomaterial Program (7 yr):Focus: Characterization and classification of nanomaterialsUnique:1) Characterization2) Goal to establish classification system

Shared:1) Materials (7 total) and cost

for synthesis2) Characterization information

Page 5: Environmental Risk Assessment of Engineered Nanomaterials

ERDCRemediation Risk Sensors

ToxicologyFate

Analytical

Mechanisms

Modeling

Modeling

Sorption Transport

StabilityDose Metrics