engineering 2011 12

8/2/2019 Engineering 2011 12

1/183

Case Western Reserve University 1

Table of Contents

Case School of Engineering ...................................................................... 2

Degree Program in Engineering - Undesignated ................................................... 18

Department of Biomedical Engineering .................................................................. 20

Department of Chemical Engineering ..................................................................... 48

Department of Civil Engineering ............................................................................. 64

Department of Electrical Engineering and Computer Science .............................. 77

Department of Macromolecular Science and Engineering .................................. 116

Department of Materials Science and Engineering .............................................. 135

Department of Mechanical and Aerospace Engineering ..................................... 156

Division of Education and Student Programs ...................................................... 177

Engineering Physics ............................................................................................... 179

Master of Engineering and Management .............................................................. 182

8/2/2019 Engineering 2011 12

2/183

2 Case School of Engineering

Case School of Engineering

Engineering seeks to create new processes,products, methods, materials, or systems thatimpact and are beneficial to our society. To

enable its graduates to lead the advancement oftechnology, the Case School of Engineering offersthirteen degree programs at the undergraduatelevel (twelve engineering degrees, plus theB.S. in computer science). At the post-graduatelevel, the School of Engineering offers Master ofScience programs and the Doctor of Philosophy foradvanced, research-based study in engineering.Case School of Engineering offers two specializeddegrees at the masters level: a Master ofEngineering specifically for practicing engineers,and an integrated Master of Engineering andManagement jointly administered with theWeatherhead School of Management. The Case

School of Engineering, also, offers two dual-degrees at the graduate level jointly administeredwith the School of Medicine: a Doctor of Medicine/Master of Science and a Doctor of Medicine/Doctorof Philosophy. The faculty and students participatein a variety of research activities offered throughthe departments and the interdisciplinary researchcenters of the University.

At the core of its vision, the Case School ofEngineering seeks to set the standards forexcellence, innovation, and distinction inengineering education and research prominence.

Statement of EducationalPhilosophy

The Case School of Engineering prepares andchallenges its students to take positions ofleadership in the professions of engineering andcomputer science. Recognizing the increasing roleof technology in virtually every facet of our society,it is vital that engineering students have access toprogressive and cutting-edge programs stressingfive areas of excellence

Mastery of fundamentals

Creativity

Societal awareness

Leadership skills

Professionalism

Emphasizing these core values helps ensure thattomorrows graduates are valued and contributing

members of our global society and that they willcarry out the tradition of engineering leadershipestablished by our alumni.

The undergraduate program aims to create life-longlearners by emphasizing engineering fundamentalsbased on mathematics, physical and naturalsciences. Curricular programs are infused withengineering innovation, professionalism (includingengineering ethics and the role of engineering insociety), professional communications, and multi-disciplinary experiences to encourage and developleadership skills. To encourage societal awareness,students are exposed to and have the opportunityfor in-depth study in the humanities, socialsciences, and business aspects of engineering.Undergraduate students are encouraged to

develop as professionals. Opportunities includethe Cooperative Education Program, on-campusresearch activities, and participation in the studentchapters of professional societies. Graduates areprepared to enter the workforce and be strongcontributors as practicing engineers, or continue foradvanced study in engineering.

At the graduate level, the Case School ofEngineering combines advanced classroom studywith a rigorous independent research experienceleading to significant results appropriate forpublication in archival journals and/or presentationat leading technical conferences. Scientific integrity,

engineering ethics, and communication skills areemphasized throughout the program.

Brief History

The Case School of Engineering was establishedon July 1, 1992, by an action of the Board ofTrustees of Case Western Reserve University asa professional school dedicated to serving societyand meeting the needs of industry, governmentand academia through programs of teaching andresearch.

The Case School of Engineering continuesthe tradition of rigorous programs based onfundamental principles of mathematics, science andengineering that have been the hallmark of its twopredecessors, the Case School of Applied Science(1880) and the Case Institute of Technology (1947).The formation of the Case School of Engineeringis a re-commitment to the obligations of the gift ofLeonard Case Jr., to serve the citizens of NorthernOhio. The School of Engineering has been aleader in many educational programs, being thefirst engineering school to offer undergraduateprograms in computer engineering, biomedical

8/2/2019 Engineering 2011 12

3/183


engineering, polymer engineering and systems andcontrol engineering.

Accreditation

The Case School of Engineering has the followingaccreditations:

Engineering Accreditation Commission of ABET,Inc. (engineering)

Computing Accreditation Commission of ABET, Inc.(computer science)

Accreditation Council for Cooperative Education(cooperative education programs)

Bachelor of Science I Master of Science | Masterof Engineering | Master of Engineering andManagement | Doctorate

Engineering Degrees Granted

Bachelor of Science in Engineering with thefollowing major field designations:

Aerospace Engineering

Biomedical Engineering

Chemical Engineering

Civil Engineering

Computer Engineering

Electrical Engineering

Engineering Physics

Materials Science and Engineering

Mechanical Engineering

Polymer Science and Engineering

Systems and Control Engineering

Bachelor of Science in Engineering(Undesignated) (for programs that emphasizeinterdisciplinary areas or for programs that include

some emphasis on non-technical fields. This is notan accredited degree)

Bachelor of Science in Computer Science(accredited by the Computing AccreditationCommission of ABET, Inc.)

Bachelor of Science in Engineering/Master ofScience




Civil Engineering


Computing and Information Science


Engineering Physics





Master of Science with the following major fielddesignations:




Civil Engineering




Macromolecular Science and Engineering




Master of Science (Undesignated)

Doctor of Medicine/Master of Science

8/2/2019 Engineering 2011 12

4/183



Master of Engineering (practice-orientedprogram)

Master of Engineering and Management

Doctor of Philosophy with the following major fielddesignations:




Civil Engineering




Macromolecular Science




Doctor of Medicine/Doctor of Philosophy



Bachelor of Science inEngineering

In addition to the major department requirements,each engineering undergraduate degree programincludes the Engineering Core, which providesa foundation in mathematics and sciences aswell as aspects of engineering fundamentals for

programs in engineering. The Engineering Corealso is designed to develop communication skillsand to provide a body of work in the humanities andsocial sciences. Requirements of the EngineeringCore can be found in the Undergraduate Studiessection of this bulletin.

Details of the specific curricular requirements forthe undergraduate majors are described in therespective departmental descriptions. Details ofthe requirements of the undesignated engineeringundergraduate degree are described under theEngineering Undesignated description.

Undergraduate Core Courses(ENGR)

ENGR 131. Elementary Computer Programming.

3 Units.

Students will learn the fundamentals of computerprogramming and algorithmic problem solving.Concepts are illustrated using a wide range ofexamples from engineering, science, and otherdisciplines. Students learn how to create, debug,and test computer programs, and how to developalgorithmic solution to problems and write programsthat implement those solutions. Matlab is theprimary programming language used in this course,but other languages may be introduced or usedthroughout.

ENGR 145. Chemistry of Materials. 4 Units.

Application of fundamental chemistry principles tomaterials. Emphasis is on bonding and how thisrelates to the structure and properties in metals,ceramics, polymers and electronic materials.Application of chemistry principles to develop anunderstanding of how to synthesize materials.Prereq: CHEM 111 or equivalent.

ENGR 200. Statics and Strength of Materials. 3Units.

An introduction to the analysis, behavior anddesign of mechanical/structural systems. Coursetopics include: concepts of equilibrium; geometricproperties and distributed forces; stress, strainand mechanical properties of materials; and, linearelastic behavior of elements. Prereq: PHYS 121.

8/2/2019 Engineering 2011 12

5/183


ENGR 210. Introduction to Circuits andInstrumentation. 4 Units.

Modeling and circuit analysis of analog anddigital circuits. Fundamental concepts in circuitanalysis: voltage and current sources; KirchhoffsLaws; Thevenin and Norton equivalent circuits,

inductors capacitors, and transformers; modelingsensors and amplifiers and measuring DC devicecharacteristics; characterization and measurementof time dependent waveforms; transient behavior ofcircuits; frequency dependent behavior of devicesand amplifiers; frequency measurements; AC powerand power measurements; noise in real electronicsystems; electronic devices as switches; digitallogic circuits; introduction to computer interfaces;and analog/digital systems for measurement andcontrol. Prereq: MATH 122. Prereq or Coreq: PHYS122.

ENGR 225. Thermodynamics, Fluid Dynamics,Heat and Mass Transfer. 4 Units.

Elementary thermodynamic concepts: first andsecond laws, and equilibrium. Basic fluid dynamics,heat transfer, and mass transfer: microscopic andmacroscopic perspectives. Prereq: CHEM 111,ENGR 145, and PHYS 121. Coreq: MATH 223.

ENGR 398. Professional Communication forEngineers. 1 Unit.

Students will attend lectures on global, economic,

environmental, and societal issues in engineering,which will be the basis for class discussions, writtenassignments and oral presentations in ENGL 398.Recommended preparation: ENGL 150 or FSCC100 or equivalent and concurrent enrollment inENGL 398 (ENGL 398 and ENGR 398 togetherform an approved SAGES departmental seminar).

Master of Science

Recognizing the different needs and objectivesof resident and non-resident graduate studentspursuing the masters degree, two differentplans are offered. In both plans, transfer of creditfrom another university is limited to six hoursof graduate-level courses, taken in excess ofthe requirements for an undergraduate degree,approved by the students advisor, the departmentchair, and the dean of graduate studies.

All Master of Science degree programs require thesubmission of a Planned Program of Study via theStudent Information System where it will be routedfor appropriate approvals. Students must submitan approved program of study by the end of the

second semester. A revised program of study mustbe submitted via the Student Information Systemwhen any change in the original plan occurs.

Masters Thesis Plan

Minimum requirements for the degree of Master ofScience in a major field under this plan are:

1. Completion of 18 hours of graduate coursework. The courses must be approved by thedepartment offering the degree.

2. Completion of nine hours of thesis workculminating in a thesis examination given byat least three professors, plus approval by thechair of the department offering the degree. Astudent with research experience equivalent toa thesis may petition the Graduate Committeeof the Case School of Engineering forsubstitution of nine hours of course work forthe thesis requirement. In this case, the thesisexamination above is replaced by a similarexamination covering the submitted researchwork and publications.

At least 18 hours of total course work, in addition to9 hours of thesis research, must be at the 400 levelor higher.

Masters Comprehensive Plan

Students may pursue either a project or non-projecttrack under this option. Minimum requirements forthe degree of Master of Science in a major fieldunder this plan are one of the following:

Project track

Completion of 27 hours of graduate course workincluding three to six hours of Special Problems.Special Problems course work must consist ofan engineering project approved by the chair ofthe department offering the degree, and may be

carried out at the students place of employmentwith nominal supervision by a faculty advisor or inthe schools laboratories under direct supervision.The project must culminate in a written reportand examination by at least three professors plusapproval by the chair of the department offeringthe degree. The Special Problems course maybe waived for students who have had industrialdesign or research experience and who submitsufficient evidence of this experience in the form ofa publication or internal report. For these students,a minimum of 27 hours of course work and thefinal oral examination covering the submitted

8/2/2019 Engineering 2011 12

6/183


publications or reports as well as related coursematerial will be required for the masters degree.At least 18 hours of course work including up to 6hours of Special Problems must be at the 400 levelor higher.

Non-project track

Students who register for 27 hours, not includingSpecial Problems course work, must passsatisfactorily a comprehensive examination tobe administered by the department or curricularprogram committee. The examination may bewritten or oral or both. A student must be registeredduring the semester in which any part of thecomprehensive examination is taken. If notregistered for other courses, the student will berequired to register for one semester hour of EXAM600, Comprehensive Examination, before taking the

examination.

Doctor of Medicine/Master ofScience

Medicine is undergoing a transformation basedon the rapid advances in science and technologythat are combining to produce more accuratediagnoses, more effective treatments with fewerside effects, and improved ability to preventdisease. The goal of the MD/MS in Engineeringis to prepare medical graduates to be leaders in

the development and clinical deployment of thistechnology and to partner with others in technologybased translational research teams. For furtherinformation, see the MD/MS Program in theBiomedical Engineering graduate section of thisbulletin. Interested students should apply throughthe biomedical engineering department.

Master of Engineering

The Master of Engineering Program is a graduatedegree program that targets currently employed

engineers. The objective of this program is toprovide engineers in industry with technical as wellas business, management, and teamwork skills.The program differs from a traditional Master ofScience degree in engineering by combining corecourses that focus on the engineering-businessenvironment and technical elective courses thatconcentrate on contemporary industrial practicerather than on research.

The Master of Engineering Program preparesstudents to enhance their role as corporate leadersand provides an environment in which practicingengineering professionals can address the

increasingly wide range of technical, management,financial and interpersonal skills demanded by anever-expanding and diverse global industry base.

The Master of Engineering Program requires30 credit hours of course work that include 18credit hours of core courses and 12 credit hours

of technical electives that are chosen from focusareas (see below). It is possible to complete theMaster of Engineering degree program within a two-year (six semester), part-time, program of study,although most students choose to complete theprogram over a seven-nine semester period. Thecore courses are aimed at equipping participantswith knowledge on how engineering is practiced incontemporary industry, and the technical electivecourses provide depth in a chosen specialty area.All courses are held in the late afternoon or eveninghours and many are provided in a distancelearningformat to minimize disruption at the workplace andhome. Because the program makes extensive use

of computers, participants need to have access tocomputer facilities.

Curriculum

The program consists of a set of six core coursesand a four course technical elective sequence (atotal of 30 credit hours are required). The corecourses provide a common base of study andexperience with problems, issues, and challengesin the engineering business environment. Thetechnical course sequence provides an opportunity

to update disciplinary engineering skills and tobroaden interdisciplinary skills. Up to six transfercredits may be approved for graduate-levelcourses taken at Case Western Reserve or anotheraccredited university.

Core Courses

EPOM 400A Engineering Professionalism: TeamLeadership in Effective Groups

1

EPOM 400B Engineering Professionalism: PresentationSkills for Effective Leaders

1

EPOM 400C Engineering Professionalism: ProfessionalDevelopment

1

EPOM 401 Introduction to Business for Engineers 3

EPOM 403 Product and Process Design andImplementation

3

EPOM 405 Applied Engineering Statistics 3

EPOM 407 Engineering Economics and FinancialAnalysis

3

EPOM 409 Master of Engineering Capstone Project 3

Total Units 18

8/2/2019 Engineering 2011 12

7/183


Technical Electives

Four courses are chosen from the technicalconcentration areas below. For detailed courseofferings in these areas, please refer to the Masterof Engineering program information at on the CaseSchool of Engineering website.




Infrastructure Engineering

Macromolecular Science and Engineering

Materials Processing and Synthesis


Robotics and Control

Software Engineering

Signal Processing and Communications

Master of Engineering andManagement

The Master of Engineering and Management

program is designed to meet the needs of studentsseeking to excel in engineering careers in industry.The MEM degree requires only one calendar yearof additional study and may be entered followinga students Junior or Senior year. The programprepares engineers to work in different businessenvironments. A rigorous curriculum preparesgraduates to build synergy between the technicalpossibilities of engineering and the profit-lossresponsibilities of management. This programevolved after years of research and interviewswith over 110 professionals and twenty-eightcorporations in the U.S.

The Program

The program includes 42 credit hours of gradedcourse work. The ten-course core sequence makesup 30 of these hours. Students choose an area ofconcentration, either technology entrepreneurshipor biomedical entrepreneurship, for the remaining12 credits. The Program prepares participantsto function as technical leaders with a uniqueblend of broadened engineering and managementskills, which can have a strategic impact on theorganizations bottom line. Graduates are uniquely

positioned for rapid advancement in technology-based organizations.

Ten Core Courses

IIME 400 Professional Development 3

IIME 405 Project Management 3

IIME 410 Accounting, Finance, and EngineeringEconomics

3

IIME 415 Materials and Manufacturing Processes 3

IIME 430A Product and Process Design, Development,and Delivery I

3

IIME 430B Product and Process Design, Development,and Delivery II

3

IIME 420 Information Technology and Systems 3

IIME 425 People Issues and Change in Organizations 3

IIME 450A Engineering Entrepreneurship I 3

IIME 450B Engineering Entrepreneurship II 3

Total Units 30

Technology EntrepreneurshipConcentration

OPMT 420 Six Sigma and Quality Management 3

OPMT 477 Enterprise Resource Planning in the SupplyChain

3

Two electives: graduate level management and/orengineering, may include:

6

IIME 470 Independent Projects

Total Units 12

Biomedical EntrepreneurshipConcentration

IIME 445 Engineering Statistics for Biosciences 3

IIME 446 Models of Health Care Systems 1.5

IIME 447 Regulatory Affairs for the Biosciences 1.5

Two of the following courses: 6

EBME 403 Biomedical Instrumentation

EBME 406 Polymers in Medicine

EBME 407 Neural Interfacing

EBME 408 Engineering Tissues/Materials - Learningfrom Natures Paradigms

EBME 410 Medical Imaging Fundamentals

EBME 416 Biomaterials for Drug Delivery

EBME 417 Excitable Cells: Molecular Mechanisms

EBME 418 Electronics for Biomedical Engineering

EBME 431 Physics of Imaging

EBME 461 Biomedical Image Processing and Analysis

EBME 507 Motor System Neuroprostheses

Total Units 12

Graduate Cooperative Education(Co-op)

Graduate Cooperative Education (Co-op) is aformalized academic program that enables students

8/2/2019 Engineering 2011 12

8/183


to enhance their classroom studies with career-based experiences in industry. It is a learningexperience designed to integrate classroomtheory with practical experience and professionaldevelopment.

Course

ENGR 400C. Graduate Cooperative Education. 0Units.

An academic opportunity designed for graduatestudents to enhance their classroom, laboratory,and research learning through participation andexperience in various organizational/industrialenvironments where theory is applied to practice.Graduate Cooperative Education experiencesmay be integrated with the students thesis orresearch project areas, or be solely for the purposeof gaining professional experience related to thestudents major field of study. Registration in thiscourse will serve to maintain full-time student statusfor the period of time that the student is on a co-opassignment.

Doctor of Philosophy

The students PhD program should be designedto prepare him or her for a lifetime of creativeactivity in research and in professional engineeringpractice. This may be coupled with a teachingcareer. The mastery of a significant field of

knowledge required to accomplish this purposeis demonstrated by an original contribution toknowledge embodied in a thesis and by satisfactorycompletion of a comprehensive course programwhich is intensive in a specific area of study andincludes work in other areas related to, but notidentical with, the major field. The necessity forbreadth as well as depth in the students educationcannot be overemphasized. To this end, anyengineering department may add additionalrequirements or constraints to ensure depth andbreadth appropriate to its field.

No student may be admitted to candidacy for the

PhD degree before approval of his or her PlannedProgram of Study via the Student InformationSystem. After this approval has been obtained, itis the responsibility of the students departmentto notify the dean of graduate studies of his orher admission to candidacy after the student hasfulfilled any additional department requirements.Minimal requirements in addition to the universityrequirements are:

1. The minimum course requirement beyond theBS level is 36 credit hours of courses takenfor credit, at least 18 hours of which must be

taken at Case Western Reserve University.The following courses taken for credit will beacceptable for a PhD program of study:1. All 400-, 500-, and 600-level courses

2. Those 300-level courses approved by thestudents department up to a maximum of

three beyond the BS or a maximum of onebeyond the MS

3. Approved graduate-level courses taken atother institutions

2. A minimum depth in basic science equivalentto six semester hours (for credit) is required.This requirement is to be satisfied by coursesthat have been previously approved by thefaculty of the department in which the studentis enrolled.

3. The requirement for breadth is normallysatisfied by a minimum of 12 semester hoursof courses (for credit) outside the studentsmajor area of concentration as defined by thestudents department and does not includecourses taken to fulfill the basic sciencerequirement.

4. A minimum of three teaching experiencesas defined by the students department. Allprograms of study must include departmental400T, 500T, and 600T courses to reflect thisrequirement. All students fulfilling teachingduties must complete UNIV 400A or UNIV400B.

5. The minimum requirement for research issatisfied by at least eighteen hours of thesis(701) credits.

6. A cumulative quality-point average of 3.0or above in all courses taken for credit as agraduate student at Case Western ReserveUniversity (excluding grades in thesis researchand grades of R) is required for the award ofthe doctoral degree.

Qualifying Examination

The student must pass a qualifying examinationrelevant to his or her area of study as designatedby the curricular department with which he orshe is affiliated. For students who obtain the MSdegree from Case Western Reserve University, thequalifying examination should be taken preferablybefore the end of the students fourth semester ofgraduate study but no later than the end of the fifthsemester at the university. For students enteringwith the masters degree the examination should be

8/2/2019 Engineering 2011 12

9/183


taken no later than the end of the third semester atthe university.

Planned Program of Study

Each student is required to submit a PlannedProgram of Study, detailing his or her coursework, thesis schedule, and qualifying examinationschedule and indicating that all the minimumrequirements of the university and the faculty ofthe Case School of Engineering are satisfied. ThisPlanned Program of Study must be submittedvia the Student Information System for approvalbefore registering for the last 18 credits hours of theprogram.

If the student is pursuing the PhD degree withoutacquiring the MS degree, a petition to waivethe requirement of the MS degree should beapproved by the departmental advisor, the chairand submitted to the dean of graduate studies. Allrequired courses taken at the university beyondthe BS degree should be shown on the PlannedProgram of Study with the grade if completed. Ifthe requirements are to be fulfilled in other than thestandard ways described above, a memorandumrequesting approval should be submitted to thedean of graduate studies.

The Planned Program of Study must be submittedwithin one semester after passing the qualifyingexamination.

Doctor of Medicine/Doctor ofPhilosophy

Students with outstanding qualifications may applyto the MD/PhD program. Students interested inobtaining a combined MD/PhD, with an emphasison basic research in biomedical engineering ormechanical engineering, are strongly encouragedto explore the Medical Scientist Training Program(MSTP), administered by the School of Medicine.For further information, please see the MedicalScientist Training Program (MSTP) in the Schoolof Medicine section of this bulletin. Interestedstudents should apply through the MSTP office inthe Medical School.

Advanced Platform Technology | Case MetalCasting Laboratories | Center for CardiovascularBiomaterials | Center for In Situ Cell andTissue Imaging | CLiPS | Center for MechanicalCharacterization of Materials | MIMS | ClevelandFunctional Electrical Simulation Center | EDC |GLEI | Institute for Advanced Materials | MFL |

NCSER | Neural Engineering Center | S-DLE |SCSAM | ThinkTank | WERC

Interdisciplinary Research

CentersInterdisciplinary research centers act as intensiveincubators for students and faculty doing researchand studying applications in specialized areas.Thirteen research centers and research programsat the Case School of Engineering have beenorganized to pursue cutting-edge research incollaboration with industrial and governmentpartners. The transfer of technology to industry isemphasized in all the centers.

The educational programs of these centersencompass the training of graduate students in

advanced methods and strategies, thus preparingthem to become important contributors to industryafter graduation; the involvement of undergraduatesin research; the presentation of seminars that areopen to interested members of the community; andoutreach to public schools to keep teachers abreastof scientific advances and to kindle the interest ofstudents in seeking careers in engineering.

Back to top

Advanced Platform Technology

(APT) CenterLouis Stokes Cleveland Department of VeteransAffairs Medical Center10701 East Boulevard, Mail Stop 151 AW/APTCleveland, Ohio 44106www.aptcenter.research.va.gov (http://www.aptcenter.research.va.gov)Phone: 216-707-6421 Fax: 216-707-6420

Ronald J. Triolo, Executive Directore-mail: [email protected]

The Advanced Platform Technology (APT) Centerbrings together top faculty and researchers

from Case Western Reserve University andthe Department of Veterans Affairs to capturethe most recent developments in the fields ofmicroelectronics and material science and focusthem on the practical medical needs of individualsdisabled by sensorimotor dysfunction or limbloss. The APT Center creates novel, cross-cuttingtechnologies for the diagnosis, treatment or studyof high priority clinical conditions within a structuredframework that facilitates regulatory compliance,outsourcing by contract manufacturers, anddissemination within the rehabilitation community.Center projects to date have concentrated primarily

8/2/2019 Engineering 2011 12

10/183


on developing new materials and microsystemsfor interfacing with the nervous system, repairingorthopaedic trauma and accelerating woundhealing, replacing or restoring natural limb,somatosensory and organ system function, andboth monitoring and promoting neurological, genito-urinary and vascular health.

The APT Center was established as a VA Centerof Excellence in 2005 and is based at the LouisStokes Cleveland Department of Veterans AffairsMedical Center (LSCDVAMC). The Center is ableto provide the following resources for developing,testing and implementing neural interfaces:

1. Manufacture and supply of nerve- and muscle-based stimulating and recording electrodes

2. Neural modeling and analysis of interfacedesigns

3. Polymer and bioactive material development

4. Microelectromechanical (MEMS) systemsdesign and fabrication

5. Rapid prototyping

6. Pre-clinical in vitro and in vivo verification ofelectrode and neural interface performance

7. Circuit and software design

8. System validation and design controldocumentation

Back to top

Case Metal Casting Laboratories(CMCL)

113 White Bldg.

http://dmseg5.case.edu/groups/CMPL/

David Schwam, Director

e-mail: [email protected]

The CMCL houses state-of-the-art, melting andcasting capabilities for a wide range of ferrousand non-ferrous alloys. The facility is a uniquecombination of laboratory and industrial scaleequipment. Research projects with federal andindustrial support are carried out by teams offaculty, graduate and undergraduate students.Manufacturing of castings from ComputerAided Design, flow and solidification simulation,rapid prototyping, molding to melting andcasting. Provides hands-on experiential learning

opportunities for engineering students in laboratoryclasses and Summer Research programs.

Industrial UBE 350 Ton Vertical Squeeze castingmachine for casting high integrity parts

350kW/1000MHz Inductotherm solid-state melting

power supply with furnaces up to 1,500 lb. steel.

50 lb. vacuum melting and casting furnace drivenby a new 35kW/10kHz.

Inductotherm power supply.

Sand molding and sand testing equipment.

Permanent molds for casting test bars andevaluation of molten metal quality.

Foseco rotary degasser for non-ferrous alloys.

Lindberg 75 kW electrical melting furnace for 800

lb. of aluminum. Denison four post, hydraulic 50 ton rapid actingsqueeze caster.

Squeeze casting tooling with preheatable dies.

Equipment for melting and casting magnesiumalloys.

Computer modeling workstations with flow andheat transfer finite element software.

Thermal Fatigue Testing Units for cyclicalimmersion in molten aluminum (Dunkers).

3-D Printer for Rapid Prototyping.

100W Nd:YAG laser.

Back to top

Center for CardiovascularBiomaterials (CCB)

202 Wickenden Building (7207)www.case.edu/affil/CCB/ccbhome.htmPhone: 216-368-3005 Fax: 216-368-4969

Roger E. Marchant, Directore-mail: [email protected]

Anirban Sen Gupta, Associate DirectorPhone: 216-368-4564e-mail: [email protected]

The Center for Cardiovascular Biomaterials(CCB) carries out research and developmentprojects to investigate new biomaterials, tissueengineered materials, and targeted drug deliverysystems, for use in cardiovascular applicationsand implants. CCB also provides researchers

8/2/2019 Engineering 2011 12

11/183


access to shared use facilities, which includes highresolution microscopy such as AFM, molecularspectroscopies, surface analysis, and polymer andpeptide synthesis capabilities. The chemical andmechanical interface between the biomaterial andthe host tissue are the focus of major study, withthe goals being to improve biologic function and

biocompatibility in the response of the human bodyto implants. Current projects include investigationof thrombosis (blood clotting) and infectionmechanisms due to cardiovascular prosthesis,biomimetic design of novel biomaterials forcardiovascular and neural implants; cardiovascularand neural tissue engineering based on biomimeticdesigns. Studies at the cell and molecular levelassist our understanding of the underlyingmechanisms, so that novel biomedical materialsmay be designed, prepared, and characterized.

Back to top

Center for In Situ Cell and TissueImaging

Wickenden 307http://bme.case.edu/mechbio/facilities.htmlPhone: 216-368-5884 Fax 216-368-4969

Melissa Knothe Tate, Directoremail: [email protected]

The Center for In Situ Cell and Tissue Imaging(CISCTI) is designed to offer state of the art andcutting edge imaging capabilities to the biomedicalcommunity at Case Western Reserve University.The center showcases a custom-configuredinstrument based on the Leica TCS SP2 AOBSSpectral confocal microscope system (LeicaMicrosystems, Mannheim, Germany). The tunableacousto-optical beam splitter (AOBS) providesselection and examination of any portion of thevisible and near-IR emission wavelengths setfor a given dye or chosen for unique researchapplications; it allows for spectroscopy at lengthscales from tissue to cellular to subcellular.The microscope is configured with software forfluorescence recovery after photobleaching (FRAP),which provide diffusion rates of fluorescence-marked macromolecules. The upright design of themicroscope allows not only examination of slidesand cell cultures, but also thicker, opaque objects.The removable stage allows use of large objects,with the confocal scanning feature still functional,because it is built into the motorized nosepieceand not into a motorized stage as in other confocalmicroscopes. For example, the system allowsfor live animal and/or cell imaging concomitantfluorescent spectroscopy, patch clamping,fluorescence recovery after photobleaching (FRAP),tracking of molecular transport (e.g. drug delivery),and digital video documentation. In order to assist

in preparation of specimens for imaging, a stateof the art histology core lab (part of CISCTI) is setup to carry out fixation, embedding, and sectioningof soft and hard tissues. Through a Ohio Board ofRegents BRTT grant (Clinical Tissue EngineeringCenter, CTEC), the CISCTI has recently acquireda stereolithography rapid prototyping system (3D

Systems Viper si2).

Back to top

Center for Layered PolymericSystems (CLiPS)

NSF Science and Technology Center420 Kent Hale Smith Building2100 Adelbert RoadCleveland, Ohio 44106-7202http://clips.case.edu

Phone: 216-368-4203 Fax: 216-368-6329Eric Baer, Directoremail: [email protected]

Exploration of multilayered polymeric systems atthe micro- and nano-layer levels reveals uniqueproperties and capabilities that are different, andoften not predicted, from systems involving thesame materials on a larger scale. Technologyrefined within CLiPS allows the production offilms and membranes composed of hundreds orthousands of layers. These extremely thin layerspromote interactions approaching the molecularlevel between the materials used in the process.

CLiPS research activities are organized intofour platforms to exploit the microlayer andnanolayer structures: (1) Rheology and NewProcessing focuses on integrating rheology into themultilayering process, and will explore combinationsof rheologically dissimilar materials to createnew polymer-based structures; (2) advancedMembranes and Transport Phenomena that exploitthe layered hierarchy to achieve unique transportproperties; (3) novel Optic and Electronic Systemsbased on the advanced layered materials, and (4)new Science and Technology Initiatives that probea fundamental understanding and explore new

opportunities for the layered structures.

CLiPS was established in 2006 with funding bythe National Science Foundation as a Scienceand Technology Center. It is the first NSF STCever to be established at Case Western ReserveUniversity. CLiPS is a national center involvingclose partnership with the University of Texas,Fisk University, the University of SouthernMississippi, and the Naval Research Laboratory,and an important educational partnership with theCleveland Metropolitan School District.

8/2/2019 Engineering 2011 12

12/183


CLiPS researchers and educators work together toaccomplish the Centers mission of advancing thenations science and technology agenda throughdevelopment of new materials and materialssystems and for educating a diverse Americanworkforce through interdisciplinary educationprograms.

Back to top

Center for MechanicalCharacterization of Materials

Charles M White Metallurgy Building

http://dmseg5.case.edu/Groups/Lewandowski/facilities.html

Phone: 216-368-4234

John J. Lewandowski, Director

email: [email protected]

The Center for Mechanical Characterizationof Materials (CMCM) was established in 1987to provide mechanical characterization (e.g.mechanical testing, deformation processing,etc.) expertise to the CWRU campus, medical,industrial, legal, outside university, and governmentlaboratory communities. The Center, housed inthe Charles M. White Metallurgy building, currentlymaintains equipment valued in excess of $3.5Mand has been accessed by the local, national, andinternational communities. The CWRU campuscommunity can access the facility via the use ofa valid CWRU university account number that willbe charged at an internal rate for machine time,including set up and any technician time involved.Long term testing can be provided at pro-ratedcharges in consultation with the Center Director.Outside (i.e. non-CWRU) users can access thefacility via a number of different mechanisms bycontacting the Center Director. In general, theCenter is capable of mechanically evaluating anddeformation processing materials that range insize scale from the micrometer range up throughbulk quantities. This unique facility enables

mechanical characterization at loading rates aslow as one micrometer/hour (i.e. rate of fingernailgrowth!) up through impact (e.g. 3-4 meters/sec)at temperatures ranging from -196C (i.e. liquidnitrogen) up to 1400C. Monotonic as well as cyclicfatigue testing is possible in addition to evaluationsof mechanical behavior and processing withsuperimposed pressures up to 2 GPa. Materialssystems that have been investigated span therange of organic and inorganic materials, includingmetals, ceramics, polymers, composites, electronicmaterials, and biomedical materials systems.

Descriptions of specific equipment and capabilitiesare provided with the website link.

Back to top

Center for Modeling IntegratedMetabolic Systems (MIMS)

410 Wickenden (7207)http://casemed.case.edu/mims/Phone: 216-368-4066 Fax:216-368-4969

Gerald M. Saidel, Directore-mail: [email protected]

The primary aim of the MIMS Center is to developmechanistic, mathematical models to simulatecellular metabolism in various tissues and organs(i.e., skeletal muscle, heart, brain, and adiposetissue) and to integrate these components in whole-

body models. These biologically and physiologicallybased computational models incorporate cellularmetabolic reactions and transport processesof a large number of chemical species. Modelparameters quantitatively characterize metabolicpathways and regulatory mechanisms under normaland abnormal conditions including obesity andhypoxia as well as in disease states includingtype-2 diabetes, cystic fibrosis, and chronic kidneydisease. The large-scale, complex mathematicalmodels are solved numerically using sophisticatedcomputational algorithms to simulate and analyzeexperimental responses to physiological andmetabolic changes. Model parameters are optimallyestimated by minimizing differences between modelsimulated outputs and experimental data usinglarge-scale, nonlinear optimization algorithms.Experimentally validated models are used to predictthe effects of altering metabolic processes withdisease states, pharmacological agents, diet, andphysical training.

Back to top

Cleveland Functional ElectricalStimulation Center

11000 Cedar Avenue, Suite 230www.FEScenter.org (http://www.FEScenter.org)Phone :216-231-3257 Fax: 216-231-3258

P. Hunter Peckham, Directore-mail: [email protected]

Functional electrical stimulation (FES) is theapplication of electrical currents to either generateor suppress activity in the nervous system.FES can produce and control the movement ofotherwise paralyzed limbs, for standing and handgrasp; activate visceral bodily functions, such

8/2/2019 Engineering 2011 12

13/183


as micturition; create perceptions such as skinsensibility; arrest undesired activity, such as painor spasm; and facilitate natural recovery andaccelerate motor relearning. FES is particularlypowerful and clinically relevant, since many peoplewith neurological disabilities retain the capacity forneural conduction, and are thus amenable to this

intervention.

The Center focuses its activities in four major areas;Fundamental studies to discover new knowledge;Enabling technologies for clinical application orthe discovery of knowledge; Clinical researchthat applies this knowledge and technology toindividuals with neurological dysfunction; Transferof knowledge and technology to the clinicalcommunity and to industry.

The FES Center was established as a VA RR&DCenter of Excellence in 1991 and is based at theLouis Stokes Cleveland VAMC (CVAMC). The

Center is a consortium with three institutionalpartners: CVAMC, Case Western ReserveUniversity (CWRU), and the MetroHealth MedicalCenter (MHMC). The Center accomplishes itsmission by integrating and facilitating the effortsof scientists, engineers, and clinicians throughcommon goals and directions in the major clinicalareas, and by providing mechanisms to accomplishthese goals across the institutional partners.

Back to top

Electronics Design Center (EDC)

112 Bingham (7200)www.engineering.case.edu/edc/Phone: 216-368-2935 Fax: 216-368-8738

Chung-Chiun Liu, Directoremail: [email protected]

The Electronics Design Center (EDC) is a multi-disciplinary educational and research Centerfocusing on the applications of microfabricationprocessing to the advancement of chemical andbiological micro-systems. The Center has completethick film and thin film processing facilities,

including screen printing, ink jet printing andsputtering equipments. Other facilities supportingthe microfabrication processing are also readilyavailable.

Back to top

Great Lakes Energy Institute(GLEI)

305 Olin Building (7074)energy.case.eduPhone: 216-368-0889

Dianne Anderson, Executive Directoremail: [email protected]

Great Lakes Energy Institute (GLEI), funded byover $6 million in donations has a mission to enablethe transition to advanced sustainable energygeneration, storage, distribution and utilization,through coordinated research, development, andeducation. Nine different alternative energy sectorscomprise this research, much of which coalescesunder the umbrella of utility scale power. Keyresearch sectors include:

Grid and storage building on historical strengths in

controls and sensors, providing a core to smart gridinterfaces that deal with controls and electronics forrenewable and storage grid connectivity, as well asmicrogrid development. Storage research leverages80 years of expertise in electrochemistry at CWRU.

Wind energy research is founded on controls,power management, and grid interfaces. Otherwind power research involves wind measurementand characterization, as well as mechanical,aerodynamic, and structural computationalsimulations of individual turbine components andwind farm array performance. CWRU is enhancedby the proximity of the University to the shores of a

major freshwater wind resource.Solar research in next generation photovoltaicfocuses on device development as well as thereliability of the system, stemming from a strongmaterials (both hard and soft), scientific, andresearch reputation.

Over 75 professors and researchers have engagedin energy research over the past 24 months andfunding has been earned in energy from each ofthe major federal (NSF, DOE, ARPA-E, DOD) andstate (Ohio Third Frontier) awarders, as well asmajor industry players and prominent foundations.And energy transcends the various schools of

CWRU with multidisciplinary proposals submittedby teams from the Case School of Engineering,School of Arts & Sciences, Weatherhead School ofManagement, and School of Law.

Back to top

8/2/2019 Engineering 2011 12

14/183


Institute for Advanced Materials

519 Kent Hale Smith Building

www.case.edu/advancedmaterials

Phone 216-368-4242

Stuart Rowan, Director

Email: [email protected]

The Institute for Advanced Materials is aclearinghouse for Case Western Reservesmaterials research and provides access to theuniversitys world-class expertise and state-of-the-art facilities. One of Ohios Centers of Excellencein Enabling Technologies: Advanced Materialsand Sensors, the institute matches industryand governmental partners with campus-basedcollaborators to explore solutions to real world

problems.Advanced materialspolymers, metals,ceramics, composites, and biomaterials arecornerstones to many emerging technologieslike biocompatible medical implants, energystorage, and environmentally sustainable consumerproducts. Recognizing that, in Ohio, approximatelyten percent of the states high tech workforce isengaged in advanced materials and related areaindustries, the Institute for Advanced Materialsat Case Western Reserve aims to leverage andenhance Ohios industrial base and manufacturingcapabilities, impact the global materials community,

educate future materials leaders, and serve as asingle, unified resource for advanced materialsresearch.

Approximately 100 faculty, including severalmembers of the National Academies, spanning fourschoolsEngineering, Arts & Sciences, Medicineand Dental Medicinework with industrial partnersand institutional collaborators to generate $38million of annual materials research income withsupport from the National Institute of Health, theNational Science Foundation, the US Departmentof Energy and the Department of Defense amongothers.

By harnessing the breadth of Cases research baseand creating new collaborative teams, the Institutefor Advanced Materials drives the integration ofnew materials innovations from initial ideas tomarketable technologies in energy, sustainabilityand human health.

Back to top

Microfabrication Laboratory (MFL)

342 Bingham Building (7200)http://mems.case.edu/Phone: 216-368-6117 Fax: 216-368-6888

Christian Zorman, Director

e-mail: [email protected]

MFL houses a state-of-the-art facility that providesthe latest in microfabrication and micromachiningprocesses. The Institute focuses on the applicationsof microfabrication and micromachining technologyto a wide range of sensors, actuators and othermicroelectromechanical (MEMS) systems.Application thrusts include: (i) healthcare; (ii)industrial control, automation and fault detection;(iii) portable power generation; and (iv) functionalmaterials and structures. In addition to siliconbased technology, the Institute has a uniquestrength in silicon carbide micromachining that

is particularly valuable for applications in harshenvironments. Undergraduate students, graduatestudents, and post-doctoral assistants use theInstitutes facilities to carry out their researchor special projects. Recent developments byresearchers in MFL include Schottky diode basedhydrogen sensor, high temperature oxygen sensor,nano-structure tin oxide sensor, inertial sensors,micro-size pressure sensors, wireless telemetricmicrosystems, miniature displays, micromechanicallight modulators, microvalves, and micropumps.

MFL facilities support a state-wide network, OhioMEMSNet, for MEMS research and development.

Back to top

National Center for SpaceExploration Research (NCSER)

21000 Brookpark Rd., MS 110-3Phone: 216-433-5031

Mohammad Kassemi, Chief Scientiste-mail: [email protected]

The National Center for Space Exploration

Research (NCSER) is a collaborative effortbetween the Universities Space ResearchAssociation (USRA), Case Western ReserveUniversity (CWRU), and NASA Glenn ResearchCenter (GRC) that provides GRC with specializedresearch and technology development capabilitiesessential to sustaining its leadership role in NASAmissions. Expertise resident at NCSER includesreduced gravity fluid mechanics, reduced gravitycombustion processes; heat transfer, two-phaseflow, micro-fluidics, and phase change processes;computational multiphase fluid dynamics, heat andmass transfer, computational simulation of physico-

8/2/2019 Engineering 2011 12

15/183


chemical fluid processes and human physiologicalsystems. This expertise has been applied to:

Cryogenic fluid management

On orbit repair of electronics

Spacecraft fire safety

Exploration life support

Energy storage

Dust management

Thermal management and control

Environmental monitoring/control

ISS experiment development Integrated systemhealth monitoring

Astronaut health

Planetary Surface Mobility

In situ resource utilization

Materials synthesis

Bio-fluid mechanics

Biosystems modeling

Back to top

Neural Engineering Center

112 Wickenden (7207)http://nec.case.edu/Phone: 216-368-3974 Fax: 216-368-4872

Dominique Durand, Directoremail: [email protected]

The research mission of the center is to bring tobear combined tools in physics, mathematics,chemistry, engineering and neuroscience toanalyze the mechanisms underlying neuronalfunction and to solve the clinical problemsassociated with neuronal dysfunction. Researchareas include: Neuromodulation, Neuroprostheses,Quantitative Neurophysiology, Neural Dynamics,Neuro-Mechanical Systems, Neural Regeneration,Neural Interfacing, Neural Imaging and MolecularSensing, Neuro-Magnetism, and SystemsNeuroscience. The education mission of thecenter is to provide engineers and scientists withan integrated knowledge of engineering andneuroscience capable of solving problems inneuroscience ranging from the molecules to theclinic. The center is also an outlet for technology

transfer of new ideas to be commercializedby industrial partners. The centers goals areaccomplished by fostering interdisciplinary researchbetween clinicians, scientists, students andlocal industry, educational experiences includingdidactic material, laboratory experience and clinicalexposure, and close ties to industrial partners.

Back to top

Solar-Durability and LifetimeExtension (S-DLE) Center

White Building/ S-DLE (Sun Farm) on CWRUsWest Quad

Phone: 216 368 3655

Roger H. French, Director

[email protected]

Activities in the center focus on long lifetime,environmentally exposed materials technologiessuch as photovoltaics, energy efficient lightingand building envelope applications. It is a WrightProjects center, funded by the Ohio Third Frontiercommission. We develop real-time and acceleratedprotocols for exposure to solar radiation and relatedenvironmental stressors to enable evaluation of theenvironmental durability and lifetime of materials,components, and products. Post-exposureoptical and thermo-mechanical measurementsare used to develop quantitative mechanistic

models of degradation processes in the bulk ofthe device materials and at the inherent interfacesbetween dissimilar materials. The S-DLE Centerscapabilities include:

Solar exposures: 2-axis solar trackers withmulti-sun concentrators, and power degradationmonitoring.

Solar simulators for 1 to 1000X sun exposures.

Multi-factor environmental test chambers withtemperature, humidity, freeze/thaw and cycling.

A full suite of optical, interfacial, thermo-

mechanical and electrical evaluations of materials,components and systems.

Back to top

8/2/2019 Engineering 2011 12

16/183


Swagelok Center for SurfaceAnalysis of Materials (SCSAM)

110 Glennan Building

A. H. Heuer, Director


F. Ernst, Co-Director


G.M. Michal, Co-Director


The Swagelok Center for Surface Analysis ofMaterials (SCSAM) is a multi-user analyticalfacility providing instrumentation for microstructuralcharacterization and surface and near-surface chemical analysis. The Centers 16major instruments encompass a wide rangeof characterization tools, which provide acomprehensive resource for academic researcherswho can tailor the analyses to their specific needs.

Current capabilities include four (4) ScanningElectron Microscopes (SEMs) which are equippedfor Focused Ion Beam (FIB) micromachiningand XEDS, WDS, and EBSP detectors, two (2)Transmission Electron Microscopes (TEMs)equipped with XEDS and EELS detectors, anAtomic Force Microscope (AFM), a UHV ScanningProbe system, a Laser Scanning Confocal OpticalMicroscope dedicated for materials studies,including Raman microscopy, an automatedNanoindenter, an Ion Beam Accelerator forRutherford Backscattering (RBS) and PIXE andPIGE, two (2) X-ray diffraction (XRD) systems,along with surface-specific tools for Time-of-Flight, Secondary Ion Mass Spectrometry (ToF-SIMS), Auger Electron Spectrometry, and X-RayPhotoelectron Spectroscopy (XPS), also knownas Electron Spectrometry for Chemical Analysis(ESCA).

SCSAM is administratively housed in the CaseSchool of Engineering (CSE) and is central tomuch of the research carried out by the seven

departments within CSE. However, the facility isextensively used by the Physics, Chemistry, Biologyand Geology Departments within the College ofArts and Science, and by many Departments withinthe Schools of Medicine and Dental Medicine. Inaddition to CWRU clients, many external institutionsutilize SCSAMs facilities, including NASA GlennResearch Center, the Cleveland Clinic, andnumerous Ohio universities. More than 300 usersutilize the facility in any give year.

SCSAMs instruments are housed in a centralizedarea, allowing users convenient access to state-of-the-art solutions for their analytical needs.

Back to top

ThinkTank for MultiscaleComputational Modeling of Bio-medical and Bio-inspired Systems

Department of Mechanical & AerospaceEngineering10900 Euclid AvenueGlennan 418http://bme.case.edu/mechbio/facilities.htmlPhone: 216-368-5884 Fax: 216-368-4969

Melissa Knothe Tate, Directoremail: [email protected]

Typically, computational modelers share commonapproaches to diverse research and developmentproblems. By providing a common space andinfrastructure (software licenses and hardware)for computational modelers to work, we hope topromote exchange of modeling experience andexpertise and to promote cross-departmentalas well as cross institutional collaborations. TheThinkTank provides a home for several internationalcomputational collaborations as well.

Back to top

Wind Energy Research andCommercialization (WERC) Center

307 Olin Building

Great Lakes Energy Institute

http://energy.case.edu/Ohio-WERC

Phone: (216) 368-1366, Fax: (216) 368-3209

David H. Matthiesen, Director

[email protected]

The WERC Center is a multidisciplinary center foruse by students, faculty, and industry providinginstrumentation for wind resource characterizationand research platforms in operating wind turbines.The WERC Center was established in 2010 withfunding from the Ohio Department of DevelopmentThird Frontier Wright Project and the Departmentof Energy. Additional support was provided by thefollowing inaugural industrial partners: ClevelandElectric Laboratories, The Lubrizol Corporation,Parker Hannifin Corporation, Azure Energy LLC.,

8/2/2019 Engineering 2011 12

17/183


Rockwell Automation, Inc., Swiger Coil SystemsLLC., and Wm. Sopko & Sons Co.

The instruments in the WERC Center include:

A continuous scan ZephIR LiDAR, manufacturedby Natural Power. This instrument measures

horizontal and vertical wind velocity along with winddirection at 1 Hz frequency at five user set heightsup to 200 m.

Five meteorological measurement systems: 3on campus; 1 with the off campus wind turbines;and one at the City of Clevelands water intake criblocated 3.5 miles offshore in Lake Erie.

An ice thickness sensor that is deployed at thebottom of Lake Erie each fall and retrieved in thespring.

A NorthWind 100 wind turbine manufacturedby Northern Power Systems in Barre, VT USA.

This 100kW community scale wind turbine hasa direct drive generator with full power inverters,stall control blades with a 21 m rotor diameter, anda 37 m hub height. This wind turbine is locatedon campus just east of Van Horn field and beganoperation in November, 2010.

A Vestas V-27 wind turbine originallymanufactured by Vestas in Denmark. This 225kWmedium scale wind turbine has a gearbox drivegenerator, pitch controlled blades with a 27 m rotordiameter, and a 30 m hub height. In addition it hasa 50kW generator for low wind generation. Thiswind turbine will be located at an industrial site in

Euclid, OH about 15 minutes from campus and isscheduled to begin operation in August, 2011.

A Nordex N-54 wind turbine originallymanufactured by Nordex in Germany. This 1.0MWutility scale wind turbine has a gearbox drivegenerator, stall control blades with a 54 m rotordiameter, and a 70 m hub height. In addition it hasa 200kW generator for low wind generation. Thiswind turbine will be located at an industrial site inEuclid, OH about 15 minutes from campus and isscheduled to begin operation in August, 2011.

Administration

Norman Tien, PhD(University of California, San Diego)Dean of the Case School of Engineering and NordProfessor of Engineering

John Blackwell, PhD(Leeds University)Facilities Faculty Advisor

Marc R. Buchner, PhD(Michigan State University)Faculty Director of Program Evaluation andAssessment

Laura Bulgarelli, MS(Georgia Institute of Technology)

Associate Dean of Finance and Administration

Lisa Camp(Baldwin Wallace College)Assistant Dean of Strategic Initiatives

Patrick E. Crago, PhD(Case Western Reserve University)Associate Dean of Engineering

Daniel Ducoff(University of California, Berkeley)Associate Dean of Development and ExternalAffairs

Deborah J. Fatica, MA(Bowling Green State University)Assistant Dean of the Division of Education andStudent Programs

Kenneth A. Loparo, PhD(Case Western Reserve University)Faculty Director of Continuing Education and NordProfessor of Engineering

Ica Manas-Zloczower, DSc(Technion-Israel Institute of Technology)Associate Dean of Faculty Development

Clare M. Rimnac, PhD

(Lehigh University)Associate Dean of Research and Wilbert J. AustinProfessor of Engineering

8/2/2019 Engineering 2011 12

18/183


Degree Program in Engineering, Undesignated

500 Nord Hall (7220)Patrick E. Crago, Associate Dean of [email protected]

Engineering (Undesignated)

The Case School of Engineering offersundesignated degrees at the Undergraduate andGraduate level.

Bachelor of Science inEngineering (Undesignated)

The Engineering (Undesignated) program preparesstudents who seek a technological background butdo not wish to pursue pure engineering careers.For example, some needs in the public sector,such as pollution remediation, transportation, low-cost housing, elective medical care, and crimecontrol could benefit from engineering expertise.To prepare for careers in fields that address suchproblems, the Engineering (Undesignated) programallows students to acquire some engineeringbackground, and combine it with a minor in suchprograms as management, history of technologyand science, or economics. This is not an ABET,Inc. accredited program.

A student electing an undesignated degreemust submit a clear statement of career goalssupported by a proposed course schedule withwritten justification for the selections. Thesedocuments are to be submitted to the office of theassociate dean in the Case School of Engineering.The program must be approved by the dean inthe Case School of Engineering or designate inconsultation with representatives of the major andminor departments. A total of at least 129 semestercredits are required for graduation.

Since each students program is unique, no typical

curriculum can be shown. Every program must fulfillthe requirements described below.

1. Engineering Core

2. A minimum of two engineering electivescourses selected from two of the following fourgroups:

Thermodynamics or Physical Chemistry

EMAC 351& EMAC 370

Physical Chemistry for Engineeringand Polymer Chemistry and Industry

6

CHEM 301

& CHEM 302

Introductory Physical Chemistry I

and Introductory Physical Chemistry II

6

ECHE 363 Thermodynamics of Chemical Systems 3

Signals, systems or control

EECS 304 Control Engineering I with Laboratory 3

ECHE 367 Process Control 4

EECS 246 Signals and Systems 4

or EBME 308 Biomedical Signals and Systems

Materials science

EMSE 201 Introduction to Materials Science andEngineering

3

EMAC 270 Introduction to Polymer Science andEngineering 3

EMSE 314 Electrical, Magnetic, and Optical Propertiesof Materials

3

EBME 306 Introduction to Biomedical Materials 3

EECS 321 Semiconductor Electronic Devices 4

Economics, production systems or decisiontheory

EECS 350 Operations and Systems Design 3

EECS 352 Engineering Economics and DecisionAnalysis

3

OPRE 345 Decision Theory 3

Major

The major must contain a minimum of 24 semestercredit hours of work in one of the followingengineering fields



Civil Engineering



Engineering Physics




8/2/2019 Engineering 2011 12

19/183


This work includes a senior projects laboratory(3 credits) and usually a course with a physicalmeasurements laboratory.

Minor

The minor program requires a minimum of 15semester credit hours. Minors are available withapproval of the Office of Undergraduate Studies.Minors should be developed with the help of theassociate dean in the Case School of Engineering.Minors must be approved by the departmentoffering the minor. Final approval of the minorresides with the Office of Undergraduate Studies.

Bachelor of Science in Engineering(Undesignated)

First Year UnitsFall Spring

Open elective or Humanities/Social

Sciencea

3

Principles of Chemistry for Engineers(CHEM 111)

4

Elementary Computer Programming (ENGR131)or Introduction to Programming in Java(EECS 132)or General Physics I - Mechanics (PHYS121)

3

FSCC 100 SAGES First Seminar 4

Calculus for Science and Engineering I(MATH 121)

4

PHED Physical Education Activities

Humanities/Social Science or open elective 3

Chemistry of Materials (ENGR 145) 4

Calculus for Science and Engineering II(MATH 122)

4

General Physics I - Mechanics (PHYS 121)or Elementary Computer Programming(ENGR 131)

4

PHED Physical Education Activities

Year Total: 18 15

Second Year Units

Fall Spring

USXX SAGES University Seminar 3Statics and Strength of Materials (ENGR200)

3

Calculus for Science and Engineering III(MATH 223)

3

Numerical Methods (EECS 251) 3

General Physics II - Electricity andMagnetism (PHYS 122)

4

USXX SAGES University Seminar 3

Thermodynamics, Fluid Dynamics, Heatand Mass Transfer (ENGR 225)

4

Introduction to Circuits and Instrumentation(ENGR 210)

4

Elementary Differential Equations (MATH224)

3

Introduction to Modern Physics (PHYS 221) 3

Year Total: 16 17

Third Year Units

Fall Spring

Humanities or Social Science 3

Major Concentration Course 3


Minor Concentration Course 3

Engineering elective 3

Open elective 3

Professional Communication for Engineers(ENGL 398N)

3




Engineering elective 3

Year Total: 18 15

Fourth Year Units

Fall Spring

Humanities or Social Science elective 3

Exxx 398 Engineering Senior Project




Humanities or Social Science elective 3




Open elective 3

Year Total: 12 15

Total Units in Sequence: 126

Hours required for graduation: 129

a One of these courses must be a humanities/social science course.

Master of Science in Engineering(Undesignated)

A student working toward an undesignated Master

of Science degree in engineering must selecta department. The student is responsible forsubmitting a Planned Program of Study via theStudent Information System where it will be routedfor appropriate approvals. The Planned Programof Study must contain a minimum of 9 semesterhours of course work in the department approvingthe program. A minimum of 18 semester hoursof course work for the degree must be at the 400level or higher. The student must meet all therequirements of the designated Master of Sciencedegree in engineering.

8/2/2019 Engineering 2011 12

20/183


Department of Biomedical Engineering

309 Wickenden Building (7207)http://bme.case.eduJeffrey L. Duerk, Allen H. and Constance T. Ford

Professor and [email protected]

The Department of Biomedical Engineering wasestablished in 1968 at Case Western ReserveUniversity. As one of the pioneer programs in theworld, it has become a strong and well-establishedprogram in research and education with manyunique features. It was founded on the premisethat engineering principles provide an importantbasis for innovative and unique solutions tobiomedical problems. This philosophy has beenthe guide for the successful development of theprogram, which has been emulated by many other

institutions. Quantitative engineering and analyticmethods for biomedical applications remains thecornerstone of the program and distinguishes itfrom biomedical science programs. In addition todealing with biomedical problems at the tissue andorgan-system level, the departments educationalprograms have a growing emphasis on cellularand subcellular mechanisms for understandingof fundamental processes, as well as for systemsapproaches to solving clinical problems.

Current degree programs include the BS, MS, ME,combined BS/MS, PhD, MD/MS, and MD/PhD inbiomedical engineering. In all of the BME programs

at Case, the goal is to educate engineers who canapply engineering methods to problems involvingliving systems. The Case School of Engineeringand the School of Medicine are in close proximityon the same campus. The Biomedical Engineeringfaculty members carry joint appointments in the twoschools and participate in the teaching, research,and decision-making committees of both. Thedepartment is close to several major medicalcenters (University Hospitals, Cleveland Clinic,VA Medical Center, and MetroHealth MedicalCenter). As a result, there is an unusually freeflow of academic exchange and collaboration inresearch and education among the schools and

institutions. All of Cases BME programs take fulladvantage of faculty cooperation among universitydepartments, which adds significant strength to theprograms.

Mission

To educate leaders who will integrate bothprinciples of engineering and medicine to createknowledge and discoveries that advance humanhealth and well-being. Our faculty and students

play leading roles ranging from basic sciencediscovery to the creation, clinical evolution, andcommercialization of new technologies, devices,

and therapies. In short, we are Engineering BetterHealth.

Background

Graduates in biomedical engineering areemployed in industry, hospitals, research centers,government, and universities. Biomedical engineersalso use their undergraduate training as a basisfor careers in business, medicine, law, and otherprofessions.

Research

Several research thrusts are available toaccommodate various student backgrounds andinterests. Strong research collaborations withclinical and basic science departments of theuniversity and collaborating medical centers bringa broad range of opportunities, expertise, andperspective to student research projects.

Biomaterials/Tissue Engineering/Drug and Gene Delivery

Fabrication and analysis of materials forimplantation, including neural, orthopaedic, andcardiovascular tissue engineering, biomimeticmaterials, liposomal and other structuresfor controlled, targeted drug delivery, andbiocompatible polymer surface modifications.Analysis of synthetic and biologic polymers byAFM, nanoscale structure-function relationships ofbiomaterials. Applications in the nervous system,the cardiovascular system, the musculoskeletalsystem, and cancer.

Biomedical Imaging

MRI, PET, SPECT, CT, ultrasound, acousticelastography, optical coherence tomography,cardiac electrical potential mapping, human visualperception, image-guided intervention, contrastagents. In vivo microscopic and molecular imaging,and small animal imaging.

8/2/2019 Engineering 2011 12

21/183


Biomedical Sensing

Optical sensing, electrochemical and chemicalfiber-optic sensors, chemical measurements in cellsand tissues, endoscopy.

Neural Engineering and NeuralProstheses

Neuronal mechanisms; neural interfacingfor electric and magnetic stimulation andrecording; neural dynamics, ion channels, secondmessengers; neural prostheses for control of limbmovement, bladder, bowel, and respiratory function;computational modeling of neural structures

Transport and Metabolic Systems

EngineeringModeling and analysis of tissue responses toheating (e.g., tumor ablation) and of cellularmetabolism related to organ and whole-bodyfunction in health (exercise) and disease (cardiac).

Biomechanical Systems

Computational musculoskeletal modeling, bonebiomechanics, soft tissue mechanics, control ofneuroprostheses for motor function, neuromuscular

control systems, human locomotion, cardiacmechanics.

Cardiovascular Systems

Normal cardiac physiology, pathogenesis ofcardiac diseases, therapeutic technologies;electrophysiological techniques, imagingtechnologies, mathematical modeling, generegulation, molecular biology techniques; cardiacbioelectricity and cardiac biomechanics.

Major I Specialty Electives I BS/MS I Minor

Undergraduate Programs

The Case undergraduate program leading tothe Bachelor of Science degree with a major inbiomedical engineering was established in 1972.The degree of Bachelor of Science in BiomedicalEngineering is accredited by the EngineeringAccreditation Commission of ABET, Inc.

Some BS graduates are employed in industryand medical centers. Others continue studiesin biomedical engineering and other fields.Students with engineering ability and an interestin medicine may consider the undergraduatebiomedical engineering program as an excitingalternative to conventional premedical programs.

The undergraduate program has three majorcomponents (1) Engineering Core, (2) BME Core,and (3) BME Specialty Sequence. The EngineeringCore provides a fundamental background inmathematics, sciences, and engineering. TheBME Core integrates engineering with biomedicalscience to solve biomedical problems. Hands-on experience in BME is developed throughundergraduate laboratory and project courses. Inaddition, by choosing a BME specialty sequence,the student can study a specific area in depth. Thisintegrated program is designed to ensure that BMEgraduates are competent engineers. Students mayselect open electives for educational breadth or

depth or to meet entrance requirements of medicalschool or other professional career choices. BMEfaculty serve as student advisors to guide studentsin choosing the program of study most appropriatefor individual needs and interests.

At the undergraduate level, we direct our effortstoward two educational objectives that describe theperformance of alumni 3-6 years after graduation:

1. Our graduates will successfully enter andcomplete post baccalaureate advanced degreeprograms, including those in biomedicalengineering

2. Our graduates will obtain jobs in the biomedicalarena and advance to positions of greaterresponsibility.

To achieve these post-graduation objectives, wehave defined the following program outcomes.These are skills that graduates of our programare expected to be proficient in at the time ofgraduation:

An ability to apply knowledge of mathematics,science, and engineering appropriate to thebiomedical engineering

An ability to design and conduct experiments, aswell as to analyze and interpret data

An ability to design a system, component, orprocess to meet desired needs within realisticconstraints such as economic, environmental,social, political, ethical, health and safety,manufacturability, and sustainability

An ability to function on multi-disciplinary teams

8/2/2019 Engineering 2011 12

22/183


An ability to identify, formulate, and solveengineering problems

An understanding of professional and ethicalresponsibility

An ability to communicate effectively

The ability to communicate the impact ofengineering solutions in a global, economic,environmental, and societal context

A recognition of the need for, and an ability toengage in life-long learning

A knowledge of contemporary issues

An ability to use the techniques, skills, andmodern engineering tools necessary forengineering practice

Bachelor of Science inEngineering

Major in Biomedical Engineering

Majors in Biomedical Engineering choose aspecialization sequence, with sequence-specificcourses. More information can be obtained fromthe Department of Biomedical Engineering (http://bme.case.edu).

Required Courses

Major Courses

EBME 201 Physiology-Biophysics I 3

EBME 202 Physiology-Biophysics II 3

EBME 306 Introduction to Biomedical Materials 3

EBME 308 Biomedical Signals and Systems 4

EBME 309 Modeling of Biomedical Systems 3

EBME 310 Principles of Biomedical Instrumentation 3

One of the following sequences: 2

EBME 318& EBME319

Biomedical Engineering Laboratory Iand Biomedical Engineering Laboratory II

EBME 328& EBME329

Biomedical Engineering R&D Training Iand Biomedical Engineering R&D Training II

EBME 359 Biomedical Computer Simulation Laboratory 1

EBME 360 Biomedical Instrumentation Laboratory 1

EBME 370 Principles of Biomedical Engineering Design 2

EBME 380 Biomedical Engineering Design Experience 3

or EBME 398 Senior Project Laboratory I

Sequence specific statistics course: choose from: 3

STAT 312 Basic Statistics for Engineering and Science

STAT 313 Statistics for Experimenters

STAT 332 Statistics for Signal Processing

STAT 333 Uncertainty in Engineering and Science

Specialty Sequence 7-8 courses 21-24

Total Units 52-55

Biomedical Engineering Specialty

ElectivesCommon BME specialties are biomaterials(orthopaedic, polymeric) and tissue engineering,biomechanics, bioelectric engineering, biomedicalinstrumentation (devices and sensors), biomedicalcomputing and imaging, and biomedical systemsand control. Courses for these specialties arepresented in the tables below; more informationcan be obtained from the Department of BiomedicalEngineering (http://bme.case.edu/current_students/undergrad/program/specialty_sequences.html).These specialties provide the student with a solidbackground in a well-defined area of biomedical

engineering. To meet specific educational needs,students may choose alternatives from among thesuggested electives or design unique specialtiessubject to departmental guidelines and facultyapproval.

Bioelectric Engineering

EECS 245 Electronic Circuits 4

EECS 309 Electromagnetic Fields I 3

EBME 317 Excitable Cells: Molecular Mechanisms 3

EBME 327 Bioelectric Engineering 3

Three technical electives from:

EECS 281 Logic Design and Computer Organization

EECS 311 Electromagnetic Fields II

EECS 321 Semiconductor Electronic Devices

EECS 322 Integrated Circuits and Electronic Devices

EECS 344 Electronic Analysis and Design

EECS 382 Microprocessor-Based Design


EECS 233 Introduction to Data Structures

EECS 304 Control Engineering I with Laboratory

EECS 324 Simulation Techniques in Engineering

EECS 337 Compiler Design

EECS 338 Introduction to Operating Systems

EECS 340 Algorithms and Data Structures

EECS 351 Communications and Signal Analysis

EECS 354 Digital Communications

EECS 346 Engineering Optimization

EBME 401 Biomedical Instrumentation and SignalAnalysis

EBME 407 Neural Interfacing



EBME 350 Quantitative Molecular Bioengineering

8/2/2019 Engineering 2011 12

23/183


Biomaterials (orthopaedic)

ECIV 310 Strength of Materials 3

EMAC 270 Introduction to Polymer Science andEngineering

3

EMSE 201 Introduction to Materials Science andEngineering

3

EMSE 303 Mechanical Behavior of Materials 3Three Technical electives from:

EBME 303 Structure of Biological Materials

EBME 305 Materials for Prosthetics and Orthotics

EBME 307 Biomechanical Prosthetic Systems

EBME 398 Senior Project Laboratory I



EMAC 276 Polymer Properties and Design

EMAE 172 Mechanical Manufacturing

EMAE 250 Computers in Mechanical Engineering

EMAE 415 Introduction to Musculo-skeletalBiomechanics

EMSE 202 Phase Diagrams and Transformations

EMSE 203 Applied ThermodynamicsEMSE 270 Materials Laboratory I

EMSE 301 Fundamentals of Materials Processing

EMSE 313 Engineering Applications of Materials

EMSE 360 Transport Phenomena in Materials Science

EMSE 411 Environmental Effects on Materials

Biomaterials (polymeric)

CHEM 223 Introductory Organic Chemistry I 3

EBME 303 Structure of Biological Materials 3

EMAC 270 Introduction to Polymer Science andEngineering

3

EMAC 351 Physical Chemistry for Engineering 3Three technical electives from:

EBME 315 Applied Tissue Engineering


EBME 325 Introduction to Tissue Engineering




EBME 425 Tissue Engineering and RegenerativeMedicine

ECHE 360 Transport Phenomena for ChemicalSystems

EMAC 276 Polymer Properties and Design

EMAC 370 Polymer Chemistry and Industry

EMAC 376 Polymer Engineering

EMAC 377 Polymer Processing

EMSE 335 Strategic Metals and Materials for the 21stCentury

EMAE 372 Relation of Materials to Design

Biomechanics

EBME 307 Biomechanical Prosthetic Systems 3

ECIV 310 Strength of Materials 3

EMAE 181 Dynamics 3

Technical electives from:

EMAE 172 Mechanical Manufacturing

EMAE 250 Computers in Mechanical Engineering

EMAE 290 Computer-Aided Manufacturing

EMAE 370 Design of Mechanical Elements

EMAE 372 Relation of Materials to Design

EMAE 350 Mechanical Engineering Analysis

EMAE 415 Introduction to Musculo-skeletalBiomechanics

EBME 402 Organ/Tissue Physiology and SystemsModeling

ECIV 420 Finite Element Analysis

Biomedical Computing and Imaging

EBME 320 Medical Imaging Fundamentals 3

EECS 233 Introduction to Data Structures 4

EECS 337 Compiler Design 4

Four technical electives from:

EBME 322 Applications of Biomedical Imaging

EBME 398 Senior Project Laboratory IEBME 431 Physics of Imaging

EBME 461 Biomedical Image Processing and Analysis

EBME 462 Cellular and Molecular Imaging

EECS 281 Logic Design and Computer Organization

EECS 313 Signal Processing

EECS 341 Introduction to Database Systems

EECS 340 Algorithms and Data Structures

EECS 338 Introduction to Operating Systems

EECS 391 Introduction to Artificial Intelligence

EECS 393 Software Engineering

MATH 304 Discrete Mathematics

Biomedical Instrumentation (devices)

EECS 245 Electronic Circuits 4

EECS 281 Logic Design and Computer Organization 4

EECS 344 Electronic Analysis and Design 3



EBME 398 Senior Project Laboratory I

EBME 403 Biomedical Instrumentation


ECHE 380 Electrochemical Technology

ECHE 381 Electrochemical Engineering

EECS 309 Electromagnetic Fields I

EECS 311 Electromagnetic Fields II

EECS 321 Semiconductor Electronic Devices

EECS 322 Integrated Circuits and Electronic Devices

EECS 344 Electronic Analysis and Design

EECS 382 Microprocessor-Based Design

PHYS 326 Physical Optics

Biomedical Systems and Control

EECS 233 Introduction to Data Structures 4

EECS 304 Control Engineering I with Laboratory 3

EECS 324 Simulation Techniques in Engineering 3

8/2/2019 Engineering 2011 12

24/183


EECS 346 Engineering Optimization 3


EBME 307 Biomechanical Prosthetic Systems

EBME 317 Excitable Cells: Molecular Mechanisms


or MATH449

Dynamical Models for Biology and Medicine

EBME 398 Senior Project Laboratory IEBME 409 Systems and Signals in Biomedical

Engineering

or EECS408

Introduction to Linear Systems

EECS 350 Operations and Systems Design

EECS 352 Engineering Economics and DecisionAnalysis

EECS 359 Bioinformatics in Practice

EECS 391 Introduction to Artificial Intelligence

The ENGR core natural science and math elective for this

sequence must be:*

MATH 201 Introduction to Linear Algebra

* This course cannot be double counted as a

technical elective or required course.

Notes: This gives 129 credits. Varies fromsequence to sequence.

Tissue Engineering

CHEM 223 Introductory Organic Chemistry I

engineering 2011 12

Documents