Emerging

Optical Imaging TechniquesJayakar Johnson Joseph, Johnsons Medicom (P) Ltd

www.clustermatteruniverse.net

Available Imaging techniques

in Medical fieldX-ray Imaging

NMR Imaging Ultrasound Imaging

Optical Imaging

Sources for Optical Imaging

Principles for Optical Imaging

Scattering

(Diffuse reflection)

Reflection Refraction

Dispersion Absorption

Polarization

Common Optical imaging

techniques

1. Endoscopy

2. Optical coherence tomography (OCT

3. Photoacoustic imaging

4. Diffuse Optical Tomography (DOT)

5. Raman Spectroscopy

6. Super-resolution Microscopy

7. Terahertz Tomography

1. Endoscopy

Works on reflection and total

internal reflection

Flexible tube to deliver light to

a surface in an organ or tissue

Sensing the reflected rays

Record images of the

digestive tract by a tiny

camera.

Pictures gastrointestinal tract

not reachable by Flexible

tube endoscopy.

2. Optical coherence Tomography

Based on low-coherence Interferometry

Typically employing near-infrared light

Interferometry

3. Photoacoustic imaging

Melanoma

4. Diffuse Optical Tomography (DOT)

Near infrared optical tomography (NIROT)

Fluorescence diffuse optical tomography (FDOT)

Classification

Liver

5. Raman Spectroscopy

Based on inelastic scattering of monochromatic light from a laser

in the visible, near infrared, or near ultraviolet range.

6. Super-resolution Microscopy

Super-resolution techniques allow the capture of images

with a higher resolution than the diffraction limit

7. Terahertz Tomography

Terahertz radiation is the middle ground between

microwaves and infrared light waves.

Recent instrumentations

on development or developed

A. Handheld Optical coherence

Tomography: OCT for diagnosis and monitoring

B. Enhanced endoscopy: for detection of

precancerous lesions

A. Photoacoustic ultrasound imaging: improves

minimally invasive surgery

B. Transcutaneous Raman spectroscopy: for

diagnosis of serious infections in diabetics

C. Molecular dynamics synchronised manipulator

(MDSM) to repair Bio-molecules

Instrumentation

on development by us

A. Handheld Optical coherence

Tomography (OCT)

Diagnosis and monitoring in Dentistry

B. Enhanced endoscopy

Uses, Light scattering spectroscopy (LSS) for

the detection of precancerous lesions

C. Improved Photoacoustic

Ultrasound imaging

Improves minimally invasive surgery by fusion of

intraoperative ultrasound (IOUS) images with the

video from endoscopic cameras, and preoperative

CT or MRI images

D. Transcutaneous Raman spectroscopy

For the early diagnosis of diabetic osteomyelitis

(a) Schematic of Raman spectroscopy system for in vivo

measurements on mice.

(b) Photograph of mouse restraint, showing water

cooling and anesthesia delivery subsystems

RepairData from

Detector array

E. Molecular dynamics synchronised

manipulator (MDSM)

Imaging system with

Virtual Reality manipulation

provisions to repair

Bio-molecules

Virtual Reality

Bio-molecules

Jayakar Johnson Joseph

Johnsons Medicom (P) Ltd

www.clustermatteruniverse.net