EFFICACY OF CEM-THERAPY

Selection of publications for the clinical test reviewThe publications, describing the terminated prospective controlled tests of the EHF-therapy (extreme high frequency) at the different diseases, in which the patient groups were selected by the randomization or minimization methods and compared according to the age, sex, gravity and duration of disease, a presence of attendant diseases and the investigation results were adequately statistically treated, are included into review.The clinical investigations, made on more than 8000 patients and healthy volunteers in the large medical centers of Moscow, Tomsk, Saratov, Nizhny Novgorod and etc., were meeting the selection criteria.

Treatment

The EHF-therapy effectiveness in the modes analogous to the CEM-TECH apparatus modes was assessed (noise, BRR-background resonance radiation). The EHF-therapy was isolated or at the background of a standard therapy compared to a standard therapy. The EHF-range EMR (electromagnetic radiation) effected the affected organ projections or a pathologic focus and/or the biologically active points (BAP) and zones. There was no the EHF-therapy in the control groups or there was the EHF-effect imitation, i.e. a blind placebo control.

Spine pain syndromegroup 1 is control, group 2 recieved EHF

therapy

0,00

20,00

40,00

60,00

1 2

groups

percent of recovered

Totally, 407 patients at the age of 19-83 years with the vertebral osteochondrosis neurologic manifestations were examined and treated.

Thus, an expressed anesthetic effect of the EHF-therapy at the vertebral osteochondrosis neurologic manifestations is established.

p<0,05

Cerebrovascular pathology group 1 is control, group 2 recieved EHF

therapy

0,0020,0040,0060,0080,00

1 2

groups

percent of recovered

A headache, vertigo, the arterial pressure (AP) fluctuation were abruptly eased after the EHF session in the basic group patients with an asthenic disorder. The AP was stabilized in more than 75% of patients on the 5-6 procedure (in a control group – on the 10-12 day), a headache was less intensive rapidly disappearing. The asthenic manifestations were smoothly vanishing.

p<0,05

Trigeminal neuralgia group 1 is control, group 2 recieved EHF

therapy

0,0020,0040,0060,0080,00

1 2

groups

percent of recovered

Megdiatov et al. were reporting of the EHF effective use in patients with the trigeminal neuralgia. A reduced pain intensity and a decreased incidence of the neuralgia attacks were noted in 19 of 27 patients from a group 2 (an actual EHF) compared to 4 of 25 patients from a control group, receiving a sham EHF procedure.

p<0,01

Syndrome of vegetative dystonia

p<0,0001

503 patients at the age of 5-63 years with a vegetative dystonia syndrome were examined and treated. Since the 3-4 day of treatment the fatigability, irritability, emotional liability, a sleep disturbance, headaches have been decreasing or disappearing at the EHF-therapy use. A working capacity and mood have been increasing.

Traumatic and postoperative pain syndrome

group 1 is control, group 2 recieved EHF therapy

0,00

50,00

100,00

1 2

groups

percent of recovered

p<0,05

All investigators have noted an expressed anesthetic effect of the EHF-therapy. The pain decrease in a postoperative wound was in 3-12 hours after the first session, a full disappearance of pains was beginning in the proximate 2 days. The EHF-therapy use was leading to a promedol dose three times decrease for the postoperative pain cupping. The pains in wound have been aching for 3-5 days in the control group patients.

Joint diseases group 1 is control, group 2 recieved EHF

therapy

0,00

50,00

100,00

1 2

groups

percent of recovered

p<0,05

Totally, 500 patients at the age of 25-79 years with the degenerative and dystrophic diseases of joints were examined and treated.

Before therapy

After CEM-Tech device therapy

arthritis

Stomach and duodenal ulcergroup 1 is control, group 2 recieved EHF

therapy

0,00

50,00

100,00

1 2

groups

percent of recovered

p<0,001

Totally, 913 patients with an ulcerous disease of the stomach and duodenum were examined and treated.

The ulcerous defect epithelization dates were assessed. An inclusion of the EHF-therapy into a medical complex leads to the epithelization date reduction by 2-4 days, in the average (14-16 days versus 18-20 days in a control group).

Psoriasisgroup 1 is control, group 2 recieved EHF

therapy

0,00

50,00

100,00

1 2

groups

percent of recovered

p<0,05

Totally, 336 patients at the age of 14-72 years with psoriasis were examined and treated (the extended psoriasis – in 76 humans, a psoriatic arthritis – in 58 humans).

All investigators were noting the anti-inflammatory, analgetic, regenerative effect, a resorption of infiltrates at the EHF-therapy inclusion into a medical complex.

Ischemic heart disease – antianginal effect

group 1 is control, group 2 recieved EHF therapy

0,00

50,00

100,00

1 2

groups

percent of recovered

p<0,001

Totally, 616 patients at the age of 41-69 years with the ischemic heart disease (IHD) were examined and treated.

The EHF-therapy in acute period in patients with a myocardial infarction

group 1 is control, group 2 recieved EHF therapy

0,00

50,00

100,00

1 2

groups

percent of recovered

Good clinical effect

p<0,01

group 1 is control, group 2 recieved EHF therapy

0,00

50,00

100,00

1 2

groups

percent of recovered

Satisfactory clinical effect

p<0,05

Prostatitis

Figure 1 Figure 2

Thereby, high effectiveness of EHF-therapy in bioresonance regime during chronic prostatitis was shown. EHF-therapy has expressed anesthetic action, it eliminates inflammatory occurrences, improves functional activity of prostate gland, leads to correction of immunologic disturbances and sexual function stimulation.

Intestine cancer – wound healing

group 1 is control, group 2 recieved EHF therapy

0,00

50,00

100,00

1 2

groups

percent of recovered

p<0,01

Modern indications to the EHF-therapy use in oncology in the following form:

Preparation of patients with the basic localization cancer to the combined treatment stages (preparation of the organs and systems to a surgical trauma, radial damages and a medicinal aggression).

Treatment of the attendant diseases and a prophylaxis of complications in humans from the risk groups.

Prophylaxis and elimination of complications after the special methods of treatment.

Treatment of a paraneoplastic syndrome. Increase of the other treatment method results. Symptomatic therapy of the incurable patients. Systemic correlation of the ecologic and precancerous pathology. Prophylaxis of a tumor process progress after a combined treatment.

Analysis of the publications about clinical tests let us make conclusions that EHF

influence on the organism allow to:

reduce pain of any genesis and inflammations in pathologic spots;reduce rehabilitation treatment period of the wide spectrum of diseases;increase the potential of rehabilitation treatment in the outpatient and home setting;perform primary and secondary prophylactics; rise the efficiency of medicaments use, and at the same time low the dose of prescribed medicine, and in some cases refuse from medicaments appliance.

All scientific efforts confirmed good tolerance of human body to EHF influence, and the absence of complications and side effects. The same can be applied to long-term observation of recovering patients (1-2 years), the absence or insignificant perception in the point of influence was observed (some patients had a perception of “light tingling” and “goose skin”).

There are no any revealed serious contraindications for its use, however one

should avoid its prescription in the following cases:

unstated diagnose;individual intolerance of this type of therapypregnancydriving and other work connected with danger and concentration (management of mechanisms and so forth).In the table below there are nosologic forms and registered basic effects of EHF-therapy;cardio stimulator.

In the following table you can see nosologic forms and the main

registered effects of EHF therapy:

Neuropathology1. Naturopathic manifestations of

spine osteochondrosis, including discogenic radiculopathy

Evident anesthetic effect, increase in pain threshold in local alogenic zones

2. Spine silicosis in children Evident anesthetic effect, increase in tolerance to physical activity, increase in spine excursion

3. Vertebrobazilare deficiency Disappearance or substantial decrease in headache and vertigo, blood pressure normalization

4. Brain exogeno-organic affections (traumatic, vascular, infectious-toxic and complex genesis)

Disappearance of asthenic manifestations, emotional instability, hypertension, headache, vertigo, blood pressure fluctuation, night sleep restoration

Neuropathology5. Cerebral atherosclerosis Cerebral blood flow normalization, lipidic

metabolism indicators normalization

6. Headache Significant decrease of intensity of headache and duration of attacks

7. Mono- and poly-neuropathy Analgetic effect, the speed increase of impulse conduction on nerves

8. Vegetative distony syndrome, including vegetative crisis (panic attack)

Vegetative status normalization, decrease or disappearance of headaches, improvement of geodynamics on the basis of rheography data

9. Reactive neurosis and stress reactions – treatment and prevention

Decrease or disappearance of irritability, emotional instability, sleep disturbances, increase in efficiency, mood increase

10. Cerebral spastic infantile paralysis

Decrease in muscular tone, increase in the range of active motions

Joint diseases

11. Degenerative dystrophic joint diseases (deforming osteoarthritis, Perthers’ disease, psoriatic osteoarthropathy)

Anti-inflammatory effect, increase in muscle strength, range of motions in interested joint and tolerance to physical activity

12. Hemarthrosis and hemophilic artropathy

Analgetic effect, hemostasis normalization

13.Atrophic arthritis Significant decrease in pain and morning joint stiffness, immunomodulatory effect

Surgical pathology

14. Traumatic and postsurgical skin injuries of bone and soft tissues, including complicated with suppurative inflammation and sluggish wounds

Shortening of all phases of wound process, anti-inflammatory action, regeneration stimulation, suppuration prophylactics, evident analgetic effect, decrease in the dose of analgetic medications

15. Burns Analgetic effect, fast formation of granulation tissue and epithelization

16. Posttraumatic osteomyelitis Shortening of inflammation exudative phase period and stimulation of the earlier start of reparative processes, normalization of cytomorphologic leukocyte characteristics

Surgical pathology

17. Posttraumatic stiffness Analgetic effect, normalization of microcirculation and trophic disturbances, restoration of normal range of motions

18. Acute cholecystitis Anti-inflammatory action

19. Acute pancreatitis Shortening of the treatment period, positive influence on the condition of immune system

Gastroenterology

20. Gastric ulcer and duodenal ulcer disease, including complicated with bleeding and perforation or penetration

Shortening of epithelization period of ulcer effect , decrease in the amount of recurrences

21. Incompetence of bile-excreting tracts

Faster and more effective pain and dyspepsia syndromes reduction, decrease in signs of thickening and crystallization of bile, normalization of gallbladder contractile function

22. Chronic gastroduodenitis, including the one with presence of Helicobacter pilori infection

Faster and more effective pain and dyspepsia syndromes reduction

23. Chronic pancreatitis Effective pain reduction, restoration of pancreas functions

Obstetrics and gynecology

25. Chronic adnexitis, including cases with reproductive function disorder

anesthetic effect, commissural structures softening, restoration of reproductive function

26. Miscarriage of pregnancy Growth of luteal phase term of menstrual cycle, rise of oestradiol and progesterone levels, cancel of need in hormonotherapy

27. Postabortal complications immunomodeling effect, reduction of inflammatory complications

Dermatology

25. Psoriasis Anti-inflammatory, analgetic, regenerative effect, infiltrate resorption, shortening of treatment period, decrease in the number of recurrences

26. Trophic ulcer Anti-inflammatory, analgetic, regenerative effect, infiltrate resorption, shortening of treatment period, epithelization of ulcer defects

27. Atopic dermatitis Anti-allergenic effect, itch termination

28. Microbial eczema Faster recovery

29. Acne Faster recovery

30. Neurodermatitis Skin itch decrease

Infectious and Parasitic diseases 31. Chronic opisthorchiasis Improvement of contractile function

characteristics and gallbladder volume characteristics, disappearance of opisthorhid

eggs in bile

32. Pulmonary tuberculosis, including chlamidia and mycoplasmal infections

Stabilization during pulmonary tuberculosis, decrease in occurrence of postsurgical

complications

33. Tick-borne encephalitis and tick-borreliosis

Motion activity increase, decrease in intensity of headaches and arthralgia, sleep normalization, decrease in fever period, weakness and sweating, increase of antibody titer to antigens of tick-borne encephalitis and tick-borreliosis

34. Viral hepatitis Faster recovery

35. Acute respiratory virus infections – prevention and treatment

Morbidity reduction in 2 times, disease behavior in a lighter form, decrease in the morbidity period, absence of complications of acute respiratory virus infections

Cardiology36. Ischemic heart disease: exertional angina, instable angina, myocardial infarction, arrhythmia

Evident antianginal effect, decrease in the number of episodes of painless myocardial ischemia, improvement of diastolic function of left ventricle, decrease in the number of stenocardia attacks, decrease of arrhythmia episodes, decrease in the dose of nitroglycerin, normalization of activity level of antithrombin III and erythrocyte deformability

37. Alternative hypertension, including hypertonic crisises

Hypertensive effect, decrease in resistance of peripheric vessels, improvement of arterial brain circulation indicators, decrease or disappearance of passive congestion signs, catecholamines excretion normalization

38. Noncoronary myocardial traumas (mitral valve prolapse, cardiomyopathy, myocarditis)

reduction of cardialgia episodes, improvement of life quality, normalization of hemostasis system indexes

Pulmonology38. Pneumonia Effectiveness increase and shortening of

treatment periods, prevention of lingering illness process

39. Bronchial asthma Decrease in cough and dyspnea, decrease in the need of inhalation bronchial spasmolytic, improvement in bronchial secretion discharge, decrease in the number of rales, external respiration function normalization, immunomodulative effect

40. Chronic neobstructive bronchitis Anti-inflammatory effect

41. Chronic obstructive bronchitis Reduction of bronchoobstruction syndrome

42. Lung and intrachest lymph nodes sarcoidosis

Normalization of roentgenogram indexes, immunograms and outer breath function, reduction of acerbations and relapses frequency

Stomatology

42. Adentia and dental prosthesis application

Evident anti-inflammatory effect

43. Paradontitis Evident anti-inflammatory effect, regeneration stimulation, local blood circulation normalization in paradonta

44. Gingivitis Evident anti-inflammatory effect

Oncology 45. Malignant neoplasms (cancer of large and rectum intestine, skin melanoma, stomach cancer, mammary tumor, lung cancer, ovarian cancer, and others)

Decrease in the number and intensity of polychemotherapy complications, decrease in the number of recurrences and metastases, pain relief effect

46. Benign tumors of mammary glands

Prevention of malignant degeneration, anti-inflammatory effect

47. Benign tumors of ovarian Normalization of secretion of sex hormones and immune status

48. Uterus fibromyoma Decease in node size

49. Lymphomas (lymphogranulomathosis no Hodgkin’s lymphomas)

Activation of organism antioxidative protection, suppression of free radical oxidation and normalization of proinflammatory cytokines level

Endocrinology

49. Diffuse toxic goiter Decrease in the size of thyroid gland, change in its consistency

50. Nodular goiter Disappearance or rapid decrease of solitary noduls

51. Diabetes and its complications (micro- and macro- anginophathy, hepatosis, cataract, nephropathy, cardiopathy)

Regression of complications, diabetes course stabilization, decrease in insulin dosage

Andrology

52. Andropausal disorders Increase in sexual desire, sexual function improvement

53. Benign hyperplasia of prostate gland

Increase in sexual desire, sexual function improvement

54. Chronic prostatitis Reduction of pain and dysuric syndromes, sexual function improvement

55. Secretio-toxic sterility Spermatogenesis stimulation

Eye diseases

56. Diabetic retinopathy Improvement of electrocullogram indicators, disappearance of unpleasant feeling in the eye

57. Eye inflammation diseases, including allergenic genesis

Itch termination, anti-allergenic effect

58. Degenerative retina and visual nerve diseases

Rise of visual acuity, visual spreading, improvement of microcirculation in bulbar conjunctive

Liver diseases58. Cirrhosis Normalization of biochemical indicators,

size and structure of liver

59. Chronic hepatitis Normalization of biochemical indicators, size and structure of liver

60. Hepatosis Normalization of biochemical indicators, size and structure of liver

61. Toxic affection of liver Normalization of biochemical indicators, size and structure of liver

Vessel diseases

62. Obliterating atherosclerosis of arteries of lower limbs

Elimination of pain syndrome, decrease of intermittent claudication

63. Obliterating endarteritis Elimination of pain syndrome, decrease of intermittent claudication

64. Raynaud’s disease Normalization of peripheral circulation and microcirculation

65. Post-thrombophlebitic syndrome

Elimination of pain syndrome, faster healing of trophic ulcer

Narcology

66. Chronic alcoholism Decrease in internal stress, anxiety, alcohol desire

67. Toxicomania Positive impact on psycho, emotional, and somatic spheres

Mechanisms of EHF Action

After analyzing information from literary sources, we can list the following mechanisms of EHF

action on human body:

Normalization of immune system functioning (increased number of T- and decreased number of B-lymphocytes and immunoglobulins (Ig) A and M (Bakaliuk et al., 1998), increased number of T-lymphocytes in comparison with baseline (Kuz’menko, 1998), the concentration of circulating immune complexes, B-lymphocytes and immunoglobulin G decreased and the number of T-lymphocytes and IgA increased (Shliapak et al., 1996), the decrease of CD8+ positive T-lymphocytes (Jin Z, Lin M, Xia J, Zhuang J, Yang R, Li X, et al., 2001), normalization of prior existing disimunnoglobulinea and normalization of functional activity of neutrophiles (Briskin B.C. and et al, 2003), rehabilitation of functional activity of B-lymphocytes and phagocytic activity of neutrophiles (Bukatko B.N., 2003)

Increase of nonspecific body resistance (Tumanyac E.E., Termuryanc N.A., 1997);

Normalization of lipidic metabolism indicators (increased concentration of high-density lipoproteins, decrease of triglycerides (Kuz’menko, 1998));

Normalization of pro- and anti-oxidant systems ratio (Tumanyac E.E., Temuryanc N.A., 1997);

Activation of cell regeneration (increase in proliferation of fibroblasts (Polyakova A.G. et al., 1999))

Normalization of the bioelectric brain activity (stabilization of α-rhythm) and disappearance of the pathologically slow δ-waves monitored by means of electroencephalography (Tyshkevich et al., 1998), increase in spectral facility of electroencephalogram α-rhyme (Gubarec M.Y., 1989), and rehabilitation of initially disturbed interzonal and interhemispheric interrelations of basic electroencephalogram rhymes (Stolbikov A. E. and et al, 1991)

Activation of hemopoesis in red bone marrow (Lebedeva N.N., Kotrovskaya T.I., 2002);

Normalization of rheological blood properties (lowering of blood viscosity, increase of erythrocytes deformation (Parshina S.S. and et al, 2003));

Normalization of coagulant and anticoagulative factors balance (normalization of antithrombin III level (Lopatina N.A. and et al, 2003), normalization of fibrinolitic activity and thrombocyte hemostasis (Bukatko V. N., 2003))

Normalization of vessel tone and microcirculation activation (normalization of endothelium vessel reactivity (Parshina S.S. and et al, 2003), normalization of rheogram indicators (Dikke G.B., 1999; Afanaseva T.N., Petrova V.D., 1995) and rheoencephalogramm indicators (Tcarev A.A., Kudinova M.A., 1997));

Normalization of vegetative regulation, stabilization of sympathetic and parasympathetic parts ratio of vegetative nervous system (Dikke G.B., 1999)

Normalization of kateholomin and sexual hormones secretion (Tcarev A.A., Kudinova M.A., 1997; Zaporozhan V.N. et al., 1997);

Influence on endogenous opioid system (Radzievsky et al., 2001), activation of antinociceptive system (Kirova B.N., 2000);

Antistress action – suppression of excessive activity of symphato-adrenal system and activation of stress-limiting systems (Chuyan E.N., Temuryanc N.A., 2005)

Suppression of influenza virus reproduction inside the cells and viricidic effect (Podchernyaeva R.Y. et al., 2004);

Rehabilitation of mononuclear ability to secret γ-interferon, which enables the decrease in possibility of cancer development for risk group patients (Sitko S.P. et al., 1993);

Cytoprotective action towards red marrow cells and liver during polychemotherapy (Karaeva N.P. et al., 2006)

Change in structure-dynamic characteristics of cell membranes (Semina I.G. et al., 2007);

Anti-inflammatory effect, based on stimulation of mast cell degrannulation and measurement of phagocytes’ functional activity in the center of inflammation (Gapeev A.B, Chemeris N.K., 2007);

Inhibition of skin, liver, and brain aging processes (Rodshtat I.V., 2007)

Clinical approbation has shown, that the given EHF-therapy is especially effective in cases of medicinal intolerance, presence of contra-indications to methods of traditional physio- and reflexotherapies, as well as insufficient efficiency of the mentioned ways of treatment. The use of EHF-therapy normalizing psychoemotional and regulatory processes in organism, allows to optimize rehabilitation of patients with acute and chronic diseases of various organs and organ systems.

It allowed to reject in the given owner’s manual the usual description of medical techniques as «concrete illness – a therapy technique» using principle of initial restoration regulatory processes with subsequent use of «therapy techniques of organ or organ system illness».

Possible variants of EHF-therapy use:

pathologic focus

affected organ projections

biologically active points (BAP) and zones

big blood vessels projection

Frontal viewPulmonary abnormalitiesGastritisLiver disordersGallbladder diseasesFine bowels disordersLarge bowels disordersRenal abnormalitiesChanges in hip jointChanges in knee jointUrinary bladder diseasesStenocardic syndrome Heart failureHeart ischemiaSpleen diseasesPancreas abnormalitiesProstata gland and urinary bladder diseasesSigmoid colon abnormalitiesSexual disordersMaldigestionDiseases in sexual sphere Visual acuity lossStomach diseases

Biologically active zones

Biologically active zones

Rear viewCervicalpart of spinal cord

osteochondrosisHeart abnormalitiesSpleen diseasesGastric ulcerPancreas abnormalitiesStomach diseasesLarge bowels disordersRenal abnormalitiesSexual disordersChanges in hip jointUreter abnormalitiesUrinary bladder diseasesGallbladder diseasesBile duct diseasesPulmonary abnormalitiesLiver disordersAdrenal gland diseasesFine bowels disordersDiseases of organs of small pelvis

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