développer de nouvelles variétés de blé pour une ... · développer de nouvelles variétés de...
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Développer de nouvelles variétés de blé pour une agriculture durable : une approche intégrée de la
génomique à la sélection
Breeding for economically and environmentally sustainable wheat varieties: an integrated approach
from genomics to selection
Coordinator: Jacques Le Gouis (INRA)
Project Manager: Marion Bondoux (INRA Transfert)
Angers-
Nantes
Bordeaux
Rhône-Alpes-
Auvergne
Toulouse
PACA
Versailles-Grignon
Partnership
1 competitiveness cluster
VEGEPOLYS VALLEY
10 private companies
Agri-Obtentions
BASF
Biogemma
Caussade Semences
Florimond Desprez
Limagrain Europe
KWS Momont
RAGT 2n
SECOBRA Recherches
Syngenta
1 technical institute
ARVALIS – Institut du végétal
15 public research laboratories
Centre INRA Rhône-Alpes-Auvergne
UMR GDEC (INRA-UCA)
UMR GAEL (INRA-UPMF)
Centre INRA Angers-Nantes
UPR BIA (INRA)
Centre INRA Versailles-Grignon
US EPGV (INRA)
UMR GV (INRA-UPS-CNRS-AgroParisTech)
URGI (INRA)
UMR BIOGER (INRA-AgroParisTech)
UMR EGC (INRA-AgroParisTech)
UMR Agronomie (INRA-AgroParisTech)
UMR SADAPT (INRA-AgroParisTech)
Centre INRA Bordeaux
UMR BFP (INRA-Univ. Bordeaux I&II)
Centre INRA Toulouse
UPR CNRGV (INRA)
Centre INRA PACA
UMR EMMAH (INRA-Université d’Avignon)
Le LIMOS (UCA)
GEVES (Groupe d’Etude et de contrôle des
Variétés Et des Semences)
1 project management and
technology transfer company
INRA Transfert
Budget and timing
• Total Cost: 34 M€
• Budget requested: 10 M€
9 M€
510 K€ in 2011
313 K€ in 2013
200 K€ in 2012
200 K€ in 2014
Timing:
Start: September 1, 2011
End (initial): December 31, 2019
End (revised): December 31, 2020
Structure
Scientists Breeders Farmers Consumers
WP1: Sequencing and markerdevelopment for high
throughput genotyping and candidate genes isolation
WP2: Genetics and ecophysiologie of wheat adaptation to biotic and
abiotic stress in the frame ofSustainable agricultural systems
and climate change
WP3: Characterization and exploitation
of natural genetic variability
WP4: Design, implementationand evaluation of novel
breeding strategies
WP5: Bioinformatic tools for data integration and dissemination
WP
7: P
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ct m
anag
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t
WP6: Dissemination, technology transfer & training
WP1: Sequencing and marker development for high throughput detection of polymorphisms and target trait
candidate genes isolation (E. Paux, INRA GDEC)
Sequencing(1B, WGS, trait-
associated contigs)
GenotypingMapping
(WP1, 2, 3, 4)
Marker development
(Genes, intergenicregions, ISBPs)
The BreedWheat TaBW420K SNP array
WP2: Genetics and ecophysiology of wheat adaptation to biotic and abiotic stress (S. Lafarge, Biogemma)
Our Targets:Nitrogen Use Efficiency
Grain protein compositionWater use efficiency
Heat stressDiseases resistance
Our Tools:Modelling/Innovative phenotyping
Candidate genes identificationField Trials
GWAS
Our Results:Candidate genes
Markers-associated traitsMaterials for breeding
Candidate genes identification for NUE and
heat stress tolerancePhenotyping: 3 years – 25 trialsGWAS with 92k SNPs from WP1
Modelling of plant canopy architecture and derived variables (green fraction)
WP3: Characterization and exploitation of natural genetic variability (J. Derory, Limagrain)
• Characterization of 5,000 wheat lines from
INRA collection
• Identification of new sources for abiotic stress tolerance
• Introduction into French germplasm
Creation of nine
advanced-backcross
populations using
drought/heat tolerant lines
BC1S5 available for field
phenotyping in years 7-8
WP4: Design, implementation and evaluation of novelbreeding strategies (G. Charmet, INRA GDEC)
Integrated statistical toolsfor molecular
breeding
Development of real size breeding programs
Evaluation of new ideotypesin sustainable
systems
Sociologic approach of
genotyping data production
WP5: Bioinformatics (M. Alaux, INRA URGI)
BW information system
Data integration
Specific development
First data integrated
- 471,000 SNP (WP1)
- 100,000 field datapoints (WP2)
- 5,000 genetic resources
passport data (WP3)
Name
Structure
WP6: Dissemination and technology transfer(B. Béjar, Céréales Vallée)
Public web site: https://breedwheat.fr/ Posters and brochures
( English & French)
Newsletters (French)
International Wheat Innovation Workshops
Clermont-Ferrand, November 2015 and
March 2018
TrainingsInternational conferences
Social networks: @breedwheat
Scientific publications and presentations at congresses
WP7: Project management(M. Bondoux, INRA Transfert)
Organisational structure Project meetings
Collaborative platform
Consortium management and communication
Reporting to the ANR
IP management
Interaction with other projects / initiatives