Gamma-Hydroxybutyrate(GHB)

BY: Julie Cairone

Drug Investigation Assignment

Names for GHB(date rape)

Chemical Name: Gamma-hydroxybutyrate

Brand Name: Xyrem

Street Names: Liquid X, Liquid E, Easy Lay, Georgia Home Boy, Bedtime Scoop, Grievous Bodily Harm, Salty Water

Depressant that acts on CNS Naturally found in CNS

› Protects cells from oxygen starvation Odorless Colorless Nearly Tasteless Can be liquid, pill, or powder Can be felt within the first 10-20 min

DESCRIPTION

LIQUID

POWDER

PILL

GHB Banned FDA Banned GHB GHB makers came out with GBL Used as sleep aid & muscle enhancer Street Names: firewater, lactone, blue

nitro, vitality FDA banned GBL too

http://www.youtube.com/watch?v=RncP4cem5XI&feature=fvst

Schedule January 31, 2000 Controlled Substance Schedule 1 FDA approved Schedule 4

1920- First synthesized 1960s- Used as anesthetic & hypnotic 1980s- Becomes available in food stores 1990- FDA bans over-the counter- Sale 1997-99- U.S. states place GHB in

schedules 1-5 2000-02- Becomes illegal, FDA approves

Xyrem for narcolepsy

History

Medical Use Anesthetic Hypnotic Clinical Depression Alcoholism Narcolepsy/insomnia

Physiological Effects Low Dose-Moderate

› Increased sex drive› Dizziness› Slow heart rate› Muscle tremors

High Dose:› Sweating› Blackouts/memory lapses› Respiratory arrest› Loss of coordination

Overdose:› Nausea/vomiting› Seizures› Amnesia› Irregular/shallow breathing

Psychological Effects Feelings of Euphoria Confusion Hallucinations Lowered Inhibitions

GHB Dose Common Effects

1 gram or less Relaxation similar to alcohol intoxication

1 to 2 grams Euphoria, reduced inhibitions, enhanced sensuality and sexuality, increased sensory stimulation

2 to 4 grams Speech and motor skill interference

4 or more Agitation, combativeness, confusion, loss of coordination, seizure-like posturing of the limbs, respiratory depression, urinary and fecal incontinence, vomiting, wavering states of consciousness, overdose death

ABOVE THE INFLUENCE

References http://www.erowid.org/chemicals/ghb/ghb.sht

ml

http://www.aafp.org/afp/20001201/2478.html http://www.psychoactive.org.uk/GHB/descript

ion.htm http://www.911rape.org/rape-drugs/ghb/stree

t-names