IVF & IUI

CARE-Best IVF treatment in Uttarakhand.

By. Dr Sumita Prabhakar

IVF(In-Vitro Fertilization) IVF is also known as Test Tube Baby process.

IVF is a process of artificially fertilization of Ovarian egg.

Fertilization process takes place outside the mother’s body.

This process takes place via Insemination

InseminationIt can be done by two ways:

Using father sperms

Using donor sperms.(As requirement of couple )

IVF PROCEDUREEvaluation

Down Regulation

Ovulation Induction

Monitoring

Egg Pickup

ICSI

Embryo Transfer

Embryo Freezing

Embryo Hatching

EVALUATIONFor IVF treatment, couples are advised for certain

investigations.

Ultrasound, for checking condition of ovaries and uterus.

Semen analysis and culture for other problems.

Abnormality test must be carried before IVF procedure.

Evaluation complete—procedure initiates.

DOWN REGULATION

Process starts on 21st day of month before IVF cycle.

Blood Investigation for checking LH,FSH and E2 hormones to confirm down regulation.

OVULATION INDUCTIONThis process depends on patient’s certain

conditions Age

Hormonal problems

Local protocols

FSH or HMG injections are given till desired follicles size.

MONITORINGCycle is monitored to check growth of eggs

and thickness of endometrium by ultrasound.

Sometimes estrogen level test is done by blood test.

EGG PICKUPWhen egg reached at desired size, an

injection is given for final maturation(HCG).

Ovum pickup is planned after 35-36 hrs process under sedation.

With ultrasound, eggs are extracted from follicles with the help of fine needle.

This process takes 20 min.

ICSIWhen eggs are retrieved from group of cells,

they are aspirated and after keeping them in incubator they are ready for fertilization.

IVF/ICSI fertilization process are decided by embryologist.

In case of poor count and motility ICSI is performed.

TESA/PESA is done for removing sperms from testis.

Then the embryos are left to grow in the controlled environment of incubator for 2-5 days.

EMBROYO TRANSFEREmbryologist assess the quality of embryos

and decides about embryo transfer.

With the help of soft cathedra embryos are

placed in the womb.

After some rest patient can go home.

EMBRYO FREEZING

Extra embryos are frozen in liquid nitrogen for preserving them for years.

Embryos are frozen because the transfer is electively planned as endrotrium or lining of uterus or patient has OHSS(ovarian hyper simulation syndrome).

EMBROYO HATCHINGIn this, outer lining of embryos is treated

with either laser or with certain chemicals.

This process is used to make outer lining more sticky and more adhesive to lining of womb.

It is effective in older women, in case of failures and weak lining of womb.

IUI(IntraUterine Insemination)Most commonly used assisted reproductive

technique.

Safe, cost effective and non invasive method.

Semen of husband or donor is clinically washed to improve its fertilization capability and injected into womb.

IUI INDICATIONSCervical factorsMild-moderate male sub-fertilityUnexplained infertilityImmunological factorsAn-OvulationEndometriosisMale anatomical defectsPsycosexual disorder-erection ejaculation

related problems

IUI INDICATIONSGenetic, hereditary problemsSevere sperm defectsContraindicationsSeveral tubal defectsSevere semen abnormalitiesPelvic mass or uterine cavity distortion

EVALUATIONProper timing and proper patient selection of

IUI is essential.

Detailed clinical history and physical examination of both partners is required.

If any abnormalities is suspected evaluation of hormonal problems are carried out.

IUI LABAny center doing IUI must have

TVS facility

Semen collection area

Semen preparation lab with laminar hood,

centrifuge , compound microscope, co2 incubator,

CO2 cylinders, semen fertility and storage facility.

Insemination area

SUCCESS RATEBased on age of patient and semen varies

from 6-28%

IUI is a very simple and safe procedure but certain problems may arise:

Trauma to cervix

Infection

Cramps or pain

Contact Us

Dr. Sumita PrabhakarCMI Hospital, 54, Haridwar Road, Dehradun.

Uttarakhand, India. PIN:248001Phone: 0135-6542172, 0135-2520042,

2720142, 2720238Mob: +91-7895333429

Email: sumitaprabhakar@gmail.com