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Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department

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Page 1: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Dr. Sindhu Pandit, MD, MBA

Ochsner PMR Department

Page 2: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

None

Disclosures

Page 3: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane
Page 4: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Approximately 795,000 strokes are seen each year

10% of stroke survivors recover almost completely

25% recover with minor impairments

40% experience moderate to severe impairments requiring special care

10% require care in a nursing home or other long-term care facility

15% die shortly after the stroke

The Impact

- National Stroke Association

Page 5: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

“There is increasing evidence that rehabilitation can have

a big impact on survivors’ quality of life, so the time is right to review the evidence in this complex field and highlight effective and important aspects of rehabilitation,”

- Carolee J. Winstein, Ph.D., lead author of the scientific statement published in the May 2016 issue of the American Heart Association journal Stroke

Page 6: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane
Page 7: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Prevent Complications

Minimize Impairments

Maximize Function

Goals of Rehabilitation

Page 8: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Depending on the severity of the stroke, rehabilitation

options can include:

Long term acute care

A skilled nursing facility/subacute care unit

A rehabilitation hospital with individualized inpatient therapy

Home therapy

Returning home with outpatient therapy

Post Acute Care

- National Stroke Association

Page 9: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Recovery

Resolution of edema surrounding the area of the infarct

Reperfusion of the ischemic penumbra

Diaschisis - state of low reactivity or depressed function as a result of a sudden interruption of major input to a part of the brain remote from the site of brain damage

With injury to one area of the brain, other areas of brain tissue are suddenly deprived of a major source of stimulation

Stroke Rehabilitation Clinician's Handbook –Canadian Partnership for Stroke Recovery

Page 10: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Later Recovery

Neuroplasticity - the ability of the central nervous system (CNS) to undergo structural and functional change in response to new experiences

Stroke Rehabilitation Clinician's Handbook –Canadian Partnership for Stroke Recovery

Page 11: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Timeline

Majority of neurological recovery occurs within the first 1- 3 months

Formal rehab continues for approximately 3-4 months after the event

Ongoing recovery for 6 months to a year

Page 12: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

The two most important factors which predict motor

recovery are:

Stroke Severity: The most important predictive factor which reduces the capacity for brain reorganization

Age: Younger patients demonstrate greater neurological and functional recovery and hence have a better prognosis compared to older stroke patients

Predictors

Stroke Rehabilitation Clinician's Handbook –Canadian Partnership for Stroke RecoveryAdunsky et al. 1992; Hindfelt & Nilsson 1977; Marini et al. 2001; Nedeltchev et al. 2005

Page 13: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane
Page 14: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Stroke Rehabilitation: Strengthening Synapses to Achieve Optimal OutcomesBy MosunmolaOyawusi, MD; Uri Adler, MD; and A.M. Barrett, MDToday’s Geriatric Medicine, Vol. 7 No. 5 P. 12

Page 15: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Medical Management in the Rehab Setting

Prevention of Skin breakdown and Contractures

Prevention of DVT

Bowel and Bladder Management

Hemiplegic shoulder pain

Central Pain

Fall Prevention

Seizure Prevention

Poststroke Depression

Poststroke Osteoporosis

Page 16: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Functional Assessment

Motor Impairment

Mobility

Balance

Cognition and Memory

Communication

Hearing/Visual Impairments

Dysphagia

Page 17: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Traditional rehabilitation practice has often focused

on strengthening exercises and compensatory training

Emerging studies/approaches emphasize restorative treatments to re-establish lost functions through intensive task-based practice or direct brain stimulation

Approaches to Rehab

Stroke Rehabilitation: Strengthening Synapses to Achieve Optimal OutcomesBy MosunmolaOyawusi, MD; Uri Adler, MD; and A.M. Barrett, MDToday’s Geriatric Medicine, Vol. 7 No. 5 P. 12

Page 18: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Constraint-induced movement therapy (CIMT)

Immobilizing the unaffected limb restored competent, symmetric movements in the affected limb

Approaches to Rehab

Page 19: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Functional Electrical Stimulation (FES)

Paretic muscles can be made to contract by applying electrical currents to the intact peripheral motor nerves innervating them.

electrically elicited muscle contractions are coordinated in a manner that provides function

Approaches to Rehab

Page 20: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Body-Weight-Supported Gait Training

Allows the patient to practice complex gait cycles unweighted

Allows the patient to practice nearly normal gait patterns and to avoid developing compensatory walking habits, such as hip hiking and circumduction

Involves the patient being suspended in a harness system hanging from an overhead frame

Traditionally, the frame is situated over a treadmill or flat ground, with 1 to 2 physical therapists providing assistance for balance and advancement of the paretic limb

Approaches to Rehab

Rehabilitation—Emerging Technologies, Innovative Therapies, and Future Objectives Nneka L. Ifejika-Jones & Anna M. Barrett

Page 21: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Extensive research efforts have been dedicated to dynamic

exoskeletons for neurorehabilitation

Approaches to Rehab

Page 22: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Robotic hip–knee–ankle–foot exoskeletal orthoses have

become commercially available and may help poststroke

patients to stand and walk again

Exoskeletons incorporate the actuators that move the

patient’s legs during the gait cycle, through a

preprogrammed and near-normal gait cycle

Approaches to Rehab

Page 23: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Stimulation-Based Approaches

Transcranial magnetic stimulation (TMS)

- electromagnetic technology to create an electrical current that can depolarize neurons

Approaches to Rehab

Stroke Rehabilitation: Strengthening Synapses to Achieve Optimal OutcomesBy MosunmolaOyawusi, MD; Uri Adler, MD; and A.M. Barrett, MDToday’s Geriatric Medicine, Vol. 7 No. 5 P. 12

Page 24: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Stimulation-Based Approaches

Transcranial direct current stimulation (tDCS)

- electrical stimulation to enhance cortical excitability

- Saline-soaked pads placed on the scalp apply a very weak current in 10 - 30 minute sessions to modify rather than generate neuronal activity in cortical neurons by generating an electrical field that fosters neural network interaction

Approaches to Rehab

Stroke Rehabilitation: Strengthening Synapses to Achieve Optimal OutcomesBy MosunmolaOyawusi, MD; Uri Adler, MD; and A.M. Barrett, MDToday’s Geriatric Medicine, Vol. 7 No. 5 P. 12

Page 25: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Biological therapies –

ex. stem cells, are being investigated

Alternative or complementary medicine –

Treatments such as acupuncture and oxygen therapy are being evaluated

Virtual reality for stroke rehabilitation –

a Cochrane review showed Virtual reality may be beneficial in improving upper limb function and activities of daily living function when used as an adjunct to usual care (to increase overall therapy time)

Approaches to Rehab

Page 26: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

The better we understand the choices we have been

making, either consciously or unconsciously, the more say we will have in the world we create. Neurocircuitry may be neurocircuitry, but we don't have to run on automatic.

- Jill Bolte Taylor

My Stroke Of Insight

Page 27: Dr. Sindhu Pandit, MD, MBA Ochsner PMR Department · Treatments such as acupuncture and oxygen therapy are being evaluated Virtual reality for stroke rehabilitation – a Cochrane

Thank you!