dr michael mullan publications
DESCRIPTION
There are a large number of publications detailing the research that has been carried out by Mullan and his research team at the esteemed Roskamp Institute in Sarasota and by going over the topics; one can learn that a loved one suffering from Alzheimer’s disease requires a lot of care and patience. Michael Mullan is an expert in his field and his proficiency is appreciated by many other Alzheimer researchers. The long list of qualifications he has to his name and the articles that have been published in international medical journals highlights his leading expertise on the subject of this disease.TRANSCRIPT
C:\Users\Admin\Desktop\Dr_michael_mullan_sarasota_publications.txt Tuesday, September 04, 2012 9:00 PM
Publications By Dr. Michael Mullan
President and CEO of Roskamp Institute, Sarasota, FL
1.
2012
Sean Kennelly; Laila Abdullah; Rose Anne Kenny; Venkat Mathura; Cheryl A Luis; Benoit Mouzon;
Fiona Crawford; Michael Mullan ; Brian Lawlor
Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the
antihypertensive nilvadipine in Alzheimer's patients--an open-label trial.
International journal of geriatric psychiatry 2012;27(4):415-22.
2.
2011
Laila Abdullah; Gogce Crynen; Jon Reed; Alex Bishop; John Phillips; Scott Ferguson; Benoit
Mouzon; Myles Michael Mullan ; Venkatarajan Mathura; Michael Mullan ; et al.
Proteomic CNS profile of delayed cognitive impairment in mice exposed to Gulf War agents.
Neuromolecular medicine 2011;13(4):275-88.
3.
2011
Daniel Paris; David Beaulieu-Abdelahad; Corbin Bachmeier; Jon Reed; Ghania Ait-Ghezala; Alex
Bishop; Jin Chao; Venkat Mathura; Fiona Crawford; Michael Mullan
Anatabine lowers Alzheimer's Aß production in vitro and in vivo.
European journal of pharmacology 2011;670(2-3):384-91.
4.
2011
S P Kennelly; L Abdullah; D Paris; J Parish; V Mathura; M Michael Mullan ; F Crawford; B A
Lawlor; R A Kenny
Demonstration of safety in Alzheimer's patients for intervention with an anti-hypertensive drug
Nilvadipine: results from a 6-week open label study.
International journal of geriatric psychiatry 2011;26(10):1038-45.
5.
2011
Corbin J Bachmeier; David Beaulieu-Abdelahad; Michael J Michael Mullan ; Daniel Paris
Epitope-dependent effects of Beta-amyloid antibodies on Beta-amyloid clearance in an in vitro
model of the blood-brain barrier.
Microcirculation (New York, N.Y. : 1994) 2011;18(5):373-9.
6.
2011
Corbin Bachmeier; David Beaulieu-Abdelahad; Michael Mullan ; Daniel Paris
Selective dihydropyiridine compounds facilitate the clearance of ß-amyloid across the
blood-brain barrier.
European journal of pharmacology 2011;659(2-3):124-9.
7.
2011
Corbin J Bachmeier; David Beaulieu-Abdelahad; Nowell J Ganey; Michael J Michael Mullan ; Gary M
Levin
Induction of drug efflux protein expression by venlafaxine but not desvenlafaxine.
Biopharmaceutics & drug disposition 2011;32(4):233-44.
8.
2011
Daniel Paris; Corbin Bachmeier; Nikunj Patel; Amita Quadros; Claude-Henry Volmar; Vincent
Laporte; Jim Ganey; David Beaulieu-Abdelahad; Ghania Ait-Ghezala; Fiona Crawford; et al.
Selective antihypertensive dihydropyridines lower Aß accumulation by targeting both the
production and the clearance of Aß across the blood-brain barrier.
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Molecular medicine (Cambridge, Mass.) 2011;17(3-4):149-62.
9.
2011
Pancham Bakshi; Elaina Margenthaler; Jon Reed; Fiona Crawford; Michael Mullan
Depletion of CXCR2 inhibits ?-secretase activity and amyloid-ß production in a murine model of
Alzheimer's disease.
Cytokine 2011;53(2):163-9.
10.
2011
Daniel Paris; Venkat Mathura; Ghania Ait-Ghezala; David Beaulieu-Abdelahad; Nikunj Patel;
Corbin Bachmeier; Michael Mullan
Flavonoids lower Alzheimer's Aß production via an NF?B dependent mechanism.
Bioinformation 2011;6(6):229-36.
11.
2011
Cheryl A Luis; Laila Abdullah; Ghania Ait-Ghezala; Benoit Mouzon; Andrew P Keegan; Fiona
Crawford; Michael Mullan
Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum ß-Amyloid.
International journal of Alzheimer's disease 2011;2011():786264.
12.
2010
Corbin Bachmeier; Michael Mullan ; Daniel Paris
Characterization and use of human brain microvascular endothelial cells to examine ß-amyloid
exchange in the blood-brain barrier.
Cytotechnology 2010;62(6):519-29.
13.
2010
Daniel Paris; Nowel Ganey; Magdalena Banasiak; Vincent Laporte; Nikunj Patel; Myles Michael
Mullan ; Susan F Murphy; Gi-Taek Yee; Corbin Bachmeier; Christopher Ganey; et al.
Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's
disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
2010;30(34):11251-8.
14.
2010
S Ferguson; B Mouzon; G Kayihan; M Wood; F Poon; S Doore; V Mathura; J Humphrey; B O'Steen; R
Hayes; et al.
Apolipoprotein E genotype and oxidative stress response to traumatic brain injury.
Neuroscience 2010;168(3):811-9.
15.
2010
Daniel Paris; Nowell J Ganey; Vincent Laporte; Nikunj S Patel; David Beaulieu-Abdelahad; Corbin
Bachmeier; Amelia March; Ghania Ait-Ghezala; Michael J Michael Mullan
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's
disease.
Journal of neuroinflammation 2010;7():17.
16.
2010
Nikunj S Patel; Venkatarajan S Mathura; Corbin Bachmeier; David Beaulieu-Abdelahad; Vincent
Laporte; Ophelia Weeks; Michael Mullan ; Daniel Paris
Alzheimer's beta-amyloid peptide blocks vascular endothelial growth factor mediated signaling
via direct interaction with VEGFR-2.
Journal of neurochemistry 2010;112(1):66-76.
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17.
2010
Venkatarajan S Mathura; Nikunj Patel; Corbin Bachmeier; Michael Mullan ; Daniel Paris
A 3D-QSAR model based screen for dihydropyridine-like compound library to identify inhibitors
of amyloid beta (Aß) production.
Bioinformation 2010;5(3):122-7.
18.
2009
Pancham Bakshi; Chao Jin; Pierre Broutin; Beniam Berhane; Jon Reed; Michael Mullan
Structural optimization of a CXCR2-directed antagonist that indirectly inhibits gamma-secretase
and reduces Abeta.
Bioorganic & medicinal chemistry 2009;17(23):8102-12.
19.
2009
Laila Abdullah; Cheryl Luis; Daniel Paris; Benoit Mouzon; Ghania Ait-Ghezala; Andrew P Keegan;
Duolao Wang; Fiona Crawford; Michael Mullan
Serum Abeta levels as predictors of conversion to mild cognitive impairment/Alzheimer disease
in an ADAPT subcohort.
Molecular medicine (Cambridge, Mass.) 2009;15(11-12):432-7.
20.
2009
Claude-Henry Volmar; Ghania Ait-Ghezala; Jeremy Frieling; Ophelia I Weeks; Michael J Michael
Mullan
CD40/CD40L interaction induces Abeta production and increases gamma-secretase activity
independently of tumor necrosis factor receptor associated factor (TRAF) signaling.
Experimental cell research 2009;315(13):2265-74.
21.
2009
F Crawford; M Wood; S Ferguson; V Mathura; P Gupta; J Humphrey; B Mouzon; V Laporte; E
Margenthaler; B O'Steen; et al.
Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury.
Neuroscience 2009;159(4):1349-62.
22.
2009
Cheryl A Luis; Laila Abdullah; Daniel Paris; Amita Quadros; Myles Michael Mullan ; Benoit
Mouzon; Ghania Ait-Ghezala; Fiona Crawford; Michael Mullan
Serum beta-amyloid correlates with neuropsychological impairment.
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition
2009;16(2):203-18.
23.
2009
Laila Abdullah; Cheryl Luis; Daniel Paris; Ghania Ait-ghezala; Benoit Mouzon; Elizabeth Allen;
Julia Parrish; Myles A Michael Mullan ; Scott Ferguson; Marcie Wood; et al.
High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease
patients.
Molecular medicine (Cambridge, Mass.) 2009;15(3-4):95-100.
24.
2009
Cheryl A Luis; Andrew P Keegan; Michael Mullan
Cross validation of the Montreal Cognitive Assessment in community dwelling older adults
residing in the Southeastern US.
International journal of geriatric psychiatry 2009;24(2):197-201.
25.
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2009
Venkatarajan S Mathura; Daniel Paris; Michael J Michael Mullan
A novel physico-chemical property based model for studying the effects of mutation on the
aggregation of peptides.
Protein and peptide letters 2009;16(8):991-8.
26.
2008
Pancham Bakshi; Elaina Margenthaler; Vincent Laporte; Fiona Crawford; Michael Mullan
Novel role of CXCR2 in regulation of gamma-secretase activity.
ACS chemical biology 2008;3(12):777-89.
27.
2008
Ghania Ait-ghezala; Laila Abdullah; Claude-Henry Volmar; Daniel Paris; Cheryl A Luis; Amita
Quadros; Benoit Mouzon; Myles A Michael Mullan ; Andrew P Keegan; Julia Parrish; et al.
Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's
disease.
Cytokine 2008;44(2):283-7.
28.
2008
Vincent Laporte; Ghania Ait-Ghezala; Claude-Henry Volmar; Christopher Ganey; Nowell Ganey;
Marcie Wood; Michael Mullan
CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice.
Brain research 2008;1231():132-42.
29.
2008
Michael J Michael Mullan ; Hanna Magowan; Colin D Weir
Femoral artery necrosis due to parenteral intravascular drug misuse: a case report and
literature review.
The Ulster medical journal 2008;77(3):203-4.
30.
2008
Barbara K Martin; Christine Szekely; Jason Brandt; Steven Piantadosi; John C S Breitner;
Suzanne Craft; Denis Evans; Robert Green; Michael Mullan
Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial
(ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.
Archives of neurology 2008;65(7):896-905.
31.
2008
Claude-Henry Volmar; Ghania Ait-Ghezala; Jeremy Frieling; Daniel Paris; Michael J Michael Mullan
The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta)
production.
Cytokine 2008;42(3):336-44.
32.
2008
Nikunj S Patel; Amita Quadros; Steven Brem; Marguerite Wotoczek-Obadia; Venkatarajan S Mathura;
Vincent Laporte; Michael Mullan ; Daniel Paris
Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide.
Amyloid : the international journal of experimental and clinical investigation : the official
journal of the International Society of Amyloidosis 2008;15(1):5-19.
33.
2008
Michael J Michael Mullan ; Julie L Scoffield; Pawan K Rajpal
Appendicectomy complicated by Addisons disease.
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The Ulster medical journal 2008;77(1):58-9.
34.
2007
Fiona C Crawford; Marcie Wood; Scott Ferguson; Venkatarajan S Mathura; Brandon Faza; Sarah
Wilson; Tao Fan; Barbara O'Steen; Ghania Ait-Ghezala; Ronald Hayes; et al.
Genomic analysis of response to traumatic brain injury in a mouse model of Alzheimer's disease
(APPsw).
Brain research 2007;1185():45-58.
35.
2007
Laila Abdullah; Daniel Paris; Cheryl Luis; Amita Quadros; Julia Parrish; Luis Valdes; Andrew P
Keegan; Venkatarajan Mathura; Fiona Crawford; Michael Mullan
The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels.
Neuroscience letters 2007;428(2-3):53-8.
36.
2007
Daniel Paris; Nikunj Patel; Amita Quadros; Monica Linan; Pancham Bakshi; Ghania Ait-Ghezala;
Michael Mullan
Inhibition of Abeta production by NF-kappaB inhibitors.
Neuroscience letters 2007;415(1):11-6.
37.
2007
Ghania Ait-Ghezala; Claude-Henry Volmar; Jeremy Frieling; Daniel Paris; Miles Tweed; Pancham
Bakshi; Michael Mullan
CD40 promotion of amyloid beta production occurs via the NF-kappaB pathway.
The European journal of neuroscience 2007;25(6):1685-95.
38.
2007
H Fai Poon; Laila Abdullah; Myles A Michael Mullan ; Michael J Michael Mullan ; Fiona C Crawford
Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells.
Neurochemistry international 2007;50(1):69-73.
39.
2007
Timothy A Crowell; Cheryl A Luis; David E Cox; Michael Mullan
Neuropsychological comparison of Alzheimer's disease and dementia with lewy bodies.
Dementia and geriatric cognitive disorders 2007;23(2):120-5.
40.
2007
H Fai Poon; Laila Abdullah; Jon Reed; Sarah M Doore; Cyndi Laird; Venkat Mathura; Michael
Mullan ; Fiona Crawford
Improving image analysis in 2DGE-based redox proteomics by labeling protein carbonyl with
fluorescent hydroxylamine.
Biological procedures online 2007;9():65-72.
41.
2007
Venkatarajan S Mathura; Mahendiranath Rangareddy; Pankaj Gupta; Michael Mullan
CliniProteus: A flexible clinical trials information management system.
Bioinformation 2007;2(4):163-5.
42.
2006
Fiona C Crawford; Marcie L Wood; Sarah E Wilson; Venkatarajan S Mathura; Tyler R Hollen; Freya
Geall; Deepak N Kolippakkam; Michael J Michael Mullan
Cocaine induced inflammatory response in human neuronal progenitor cells.
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Journal of neurochemistry 2006;97(3):662-74.
43.
2006
Laila Abdullah; Ghania Ait-Ghezala; Fiona Crawford; Timothy A Crowell; Warren W Barker; Ranjan
Duara; Michael Mullan
The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease.
Neuroscience letters 2006;395(3):240-3.
44.
2006
Timothy A Crowell; Juno Paramadevan; Laila Abdullah; Michael Mullan
Beneficial effect of cholinesterase inhibitor medications on recognition memory performance in
mild to moderate Alzheimer's disease: preliminary findings.
Journal of geriatric psychiatry and neurology 2006;19(1):13-5.
45.
2006
Vincent Laporte; Ghania Ait-Ghezala; Claude-Henry Volmar; Michael Mullan
CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models.
Journal of neuroinflammation 2006;3():3.
46.
2006
Amy R Borenstein; James A Mortimer; Yougui Wu; Fern M Jureidini-Webb; M Daniele Fallin; Brent J
Small; Michael Mullan ; Fiona C Crawford
Apolipoprotein E and cognition in community-based samples of African Americans and Caucasians.
Ethnicity & disease 2006;16(1):9-15.
47.
2005
Ghania Ait-Ghezala; Venkatarajan S Mathura; Vincent Laporte; Amita Quadros; Daniel Paris;
Nikunj Patel; Claude-Henry Volmar; Deepak Kolippakkam; Fiona Crawford; Mike Michael Mullan
Genomic regulation after CD40 stimulation in microglia: relevance to Alzheimer's disease.
Brain research. Molecular brain research 2005;140(1-2):73-85.
48.
2005
Venkatarajan S Mathura; Daniel Paris; Ghania Ait-Ghezala; Amita Quadros; Nikunj S Patel; Deepak
N Kolippakkam; Claude-Henry Volmar; Michael J Michael Mullan
Model of Alzheimer's disease amyloid-beta peptide based on a RNA binding protein.
Biochemical and biophysical research communications 2005;332(2):585-92.
49.
2005
Daniel Paris; Ghania Ait-Ghezala; Venkatarajan S Mathura; Nikunj Patel; Amita Quadros; Vincent
Laporte; Mike Michael Mullan
Anti-angiogenic activity of the mutant Dutch A(beta) peptide on human brain microvascular
endothelial cells.
Brain research. Molecular brain research 2005;136(1-2):212-30.
50.
2005
Daniel Paris; Amita Quadros; Nikunj Patel; Anthony DelleDonne; James Humphrey; Michael Mullan
Inhibition of angiogenesis and tumor growth by beta and gamma-secretase inhibitors.
European journal of pharmacology 2005;514(1):1-15.
51.
2005
Terrence Town; Jun Tan; Richard A Flavell; Mike Michael Mullan
T-cells in Alzheimer's disease.
Neuromolecular medicine 2005;7(3):255-64.
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52.
2004
Dylan G Harwood; Warren W Barker; Raymond L Ownby; Michael Mullan ; Ranjan Duara
No association between subjective memory complaints and apolipoprotein E genotype in
cognitively intact elderly.
International journal of geriatric psychiatry 2004;19(12):1131-9.
53.
2004
Dylan G Harwood; Warren W Barker; Raymond L Ownby; Peter St George-Hyslop; Michael Mullan ;
Ranjan Duara
Apolipoprotein E polymorphism and age of onset for Alzheimer's disease in a bi-ethnic sample.
International psychogeriatrics / IPA 2004;16(3):317-26.
54.
2004
Daniel Paris; Nikunj Patel; Anthony DelleDonne; Amita Quadros; Robert Smeed; Michael Mullan
Impaired angiogenesis in a transgenic mouse model of cerebral amyloidosis.
Neuroscience letters 2004;366(1):80-5.
55.
2004
J Todd Roach; Claude-Henry Volmar; Samvid Dwivedi; Terrence Town; Robert Crescentini; Fiona
Crawford; Jun Tan; Michael Mullan
Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice.
Brain research 2004;1015(1-2):161-8.
56.
2004
Jiazhi Sun; Michelle A Blaskovich; Rishi K Jain; Frederic Delarue; Daniel Paris; Steven Brem;
Marguerite Wotoczek-Obadia; Qing Lin; Domenico Coppola; Kihang Choi; et al.
Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits
binding of vascular endothelial growth factor to its receptor.
Cancer research 2004;64(10):3586-92.
57.
2004
Ryan T Mott; Ghania Ait-Ghezala; Terrence Town; Takashi Mori; Martina Vendrame; Jin Zeng; Jared
Ehrhart; Michae Michael Mullan ; Jun Tan
Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine
production.
Glia 2004;46(4):369-79.
58.
2004
Daniel Paris; Amita Quadros; James Humphrey; Nikunj Patel; Robert Crescentini; Fiona Crawford;
Michael Mullan
Nilvadipine antagonizes both Abeta vasoactivity in isolated arteries, and the reduced cerebral
blood flow in APPsw transgenic mice.
Brain research 2004;999(1):53-61.
59.
2004
Daniel Paris; Kirk Townsend; Amita Quadros; James Humphrey; Jiazhi Sun; Steven Brem; Marguerite
Wotoczek-Obadia; Anthony DelleDonne; Nikunj Patel; Demian F Obregon; et al.
Inhibition of angiogenesis by Abeta peptides.
Angiogenesis 2004;7(1):75-85.
60.
2003
Amita Quadros; Nikunj Patel; Robert Crescentini; Fiona Crawford; Daniel Paris; Michael Mullan
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Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw
transgenic mice.
Neuroscience letters 2003;353(1):66-8.
61.
2003
Daniel Paris; James Humphrey; Amita Quadros; Nikunj Patel; Robert Crescentini; Fiona Crawford;
Michael Mullan
Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model
of Alzheimer's disease: role of inflammation.
Neurological research 2003;25(6):642-51.
62.
2003
Fiona C Crawford; Ghania Ait-Ghezala; Mark Morris; Maxine J Sutcliffe; Robert A Hauser; Archie
A Silver; Michael J Michael Mullan
Translocation breakpoint in two unrelated Tourette syndrome cases, within a region previously
linked to the disorder.
Human genetics 2003;113(2):154-61.
63.
2002
Jun Tan; Terrence Town; Fiona Crawford; Takashi Mori; Anthony DelleDonne; Robert Crescentini;
Demian Obregon; Richard A Flavell; Michael J Michael Mullan
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice.
Nature neuroscience 2002;5(12):1288-93.
64.
2002
Terrence Town; Martina Vendrame; Anant Patel; Daniel Poetter; Anthony DelleDonne; Takashi Mori;
Robert Smeed; Fiona Crawford; Thomas Klein; Jun Tan; et al.
Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42).
Journal of neuroimmunology 2002;132(1-2):49-59.
65.
2002
Jun Tan; Terrence Town; Laila Abdullah; Yajaun Wu; Andon Placzek; Brent Small; Jodi Kroeger;
Fiona Crawford; Dan Richards; Michael Mullan
CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease.
Journal of neuroimmunology 2002;132(1-2):164-72.
66.
2002
K P Townsend; D Obregon; A Quadros; N Patel; Ch Volmar; D Paris; M Michael Mullan
Proinflammatory and vasoactive effects of Abeta in the cerebrovasculature.
Annals of the New York Academy of Sciences 2002;977():65-76.
67.
2002
Robert L Yuspeh; Rodney D Vanderploeg; Timothy A Crowell; Michael Mullan
Differences in executive functioning between Alzheimer's disease and subcortical ischemic
vascular dementia.
Journal of clinical and experimental neuropsychology 2002;24(6):745-54.
68.
2002
Daniel Paris; Kirk P Townsend; Demian F Obregon; James Humphrey; Michael Mullan
Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain.
Prostaglandins & other lipid mediators 2002;70(1-2):1-12.
69.
2002
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Terrence Town; Joseph Zolton; Reed Shaffner; Billy Schnell; Robert Crescentini; Yajuan Wu; Jin
Zeng; Anthony DelleDonne; Demian Obregon; Jun Tan; et al.
p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro.
Journal of neuroscience research 2002;69(3):362-72.
70.
2002
Jun Tan; Terrence Town; Mike Michael Mullan
CD40-CD40L interaction in Alzheimer's disease.
Current opinion in pharmacology 2002;2(4):445-51.
71.
2002
G Ait-Ghezala; L Abdullah; R Crescentini; F Crawford; T Town; S Singh; D Richards; R Duara; M
Michael Mullan
Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample.
Neuroscience letters 2002;325(2):87-90.
72.
2002
F C Crawford; R D Vanderploeg; M J Freeman; S Singh; M Waisman; L Michaels; L Abdullah; D
Warden; R Lipsky; A Salazar; et al.
APOE genotype influences acquisition and recall following traumatic brain injury.
Neurology 2002;58(7):1115-8.
73.
2002
Daniel Paris; Kirk P Townsend; James Humphrey; Demian F Obregon; Kiyoko Yokota; Michael Mullan
Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and
inflammation in rat aortae.
Atherosclerosis 2002;161(2):293-9.
74.
2002
Jun Tan; Terrence Town; Takashi Mori; Demian Obregon; Yajuan Wu; Anthony DelleDonne; Amyn
Rojiani; Fiona Crawford; Richard A Flavell; Mike Michael Mullan
CD40 is expressed and functional on neuronal cells.
The EMBO journal 2002;21(4):643-52.
75.
2002
Dylan G Harwood; Warren W Barker; Raymond L Ownby; Michael Mullan ; Ranjan Duara
Apolipoprotein E polymorphism and cognitive impairment in a bi-ethnic community-dwelling
elderly sample.
Alzheimer disease and associated disorders 2002;16(1):8-14.
76.
2002
J A Schinka; T Town; L Abdullah; F C Crawford; P I Ordorica; E Francis; P Hughes; A B Graves; J
A Mortimer; M Michael Mullan
A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and
other substances.
Molecular psychiatry 2002;7(2):224-8.
77.
2002
Dylan G Harwood; Warren W Barker; Raymond L Ownby; Michael Mullan ; Ranjan Duara
Apolipoprotein E genotype and cognitive impairment in community-dwelling black older adults.
International journal of psychiatry in medicine 2002;32(1):55-67.
78.
2001
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C Russ; J F Powell; J Zhao; M Baker; M Hutton; F Crawford; M Michael Mullan ; G Roks; M Cruts;
S Lovestone
The microtubule associated protein Tau gene and Alzheimer's disease--an association study and
meta-analysis.
Neuroscience letters 2001;314(1-2):92-6.
79.
2001
T Town; J Tan; M Michael Mullan
CD40 signaling and Alzheimer's disease pathogenesis.
Neurochemistry international 2001;39(5-6):371-80.
80.
2001
T Mori; D Paris; T Town; A M Rojiani; D L Sparks; A Delledonne; F Crawford; L I Abdullah; J A
Humphrey; D W Dickson; et al.
Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic
APP(SW) mice.
Journal of neuropathology and experimental neurology 2001;60(8):778-85.
81.
2001
T Town; J Tan; N Sansone; D Obregon; T Klein; M Michael Mullan
Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42.
Neuroscience letters 2001;307(2):101-4.
82.
2001
F C Crawford; M J Freeman; J A Schinka; M D Morris; L I Abdullah; D Richards; S Sevush; R
Duara; M J Michael Mullan
Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase
gene.
Experimental neurology 2001;167(2):456-9.
83.
2000
T Town; J Schinka; J Tan; M Michael Mullan
The opioid receptor system and alcoholism: a genetic perspective.
European journal of pharmacology 2000;410(2-3):243-248.
84.
2000
J Tan; T Town; M Michael Mullan
CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42
MAPK pathway.
The Journal of biological chemistry 2000;275(47):37224-31.
85.
2000
J Tan; T Town; T Mori; Y Wu; M Saxe; F Crawford; M Michael Mullan
CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42
mitogen-activated protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience
2000;20(20):7587-94.
86.
2000
F C Crawford; M J Freeman; J A Schinka; L I Abdullah; M Gold; R Hartman; K Krivian; M D Morris;
D Richards; R Duara; et al.
A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease.
Neurology 2000;55(6):763-8.
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87.
2000
D Paris; T Town; J Humphrey; K Yokota; M Michael Mullan
Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory
pathway.
Biochemical and biophysical research communications 2000;274(2):553-8.
88.
2000
A Tandon; E Rogaeva; M Michael Mullan ; P H St George-Hyslop
Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins.
Current opinion in neurology 2000;13(4):377-84.
89.
2000
F C Crawford; M J Freeman; J Schinka; L I Abdullah; D Richards; S Sevush; R Duara; M J Michael
Mullan
The genetic association between Cathepsin D and Alzheimer's disease.
Neuroscience letters 2000;289(1):61-5.
90.
2000
B J Small; A B Graves; C L McEvoy; F C Crawford; M Michael Mullan ; J A Mortimer
Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging?
Neurology 2000;54(11):2082-8.
91.
2000
Y M Kuo; F Crawford; M Michael Mullan ; T A Kokjohn; M R Emmerling; R O Weller; A E Roher
Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to
amyloid accumulation in Alzheimer's disease.
Molecular medicine (Cambridge, Mass.) 2000;6(5):430-9.
92.
2000
F Crawford; M Freeman; L Abdullah; J Schinka; M Gold; R Duara; M Michael Mullan
No association between the NOS3 codon 298 polymorphism and Alzheimer's disease in a sample from
the United States.
Annals of neurology 2000;47(5):687.
93.
2000
D Paris; T Town; T Parker; J Humphrey; M Michael Mullan
A beta vasoactivity: an inflammatory reaction.
Annals of the New York Academy of Sciences 2000;903():97-109.
94.
2000
Z Suo; G Su; A Placzek; A Kundtz; J Humphrey; F Crawford; M Michael Mullan
A beta vasoactivity in vivo.
Annals of the New York Academy of Sciences 2000;903():156-63.
95.
2000
D Paris; T Town; T Parker; J Humphrey; M Michael Mullan
beta-Amyloid vasoactivity and proinflammation in microglia can be blocked by cGMP-elevating
agents.
Annals of the New York Academy of Sciences 2000;903():446-50.
96.
2000
D Paris; T Town; T Mori; T A Parker; J Humphrey; M Michael Mullan
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Soluble beta-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway.
Neurobiology of aging 2000;21(2):183-97.
97.
2000
F Crawford; L Abdullah; J Schinka; Z Suo; M Gold; R Duara; M Michael Mullan
Gender-specific association of the angiotensin converting enzyme gene with Alzheimer's disease.
Neuroscience letters 2000;280(3):215-9.
98.
2000
D Paris; T Town; M Michael Mullan
Novel strategies for opposing murine microglial activation.
Neuroscience letters 2000;278(1-2):5-8.
99.
2000
S Sevush; G Peruyera; F Crawford; M Michael Mullan
Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with
Alzheimer's disease.
The American journal of geriatric psychiatry : official journal of the American Association for
Geriatric Psychiatry 2000;8(3):254-6.
100.
2000
D G Harwood; W W Barker; R L Ownby; M J Michael Mullan ; R Duara
Family history of dementia and current depression in nondemented community-dwelling older adults.
Journal of geriatric psychiatry and neurology 2000;13(2):65-71.
101.
1999
J Tan; T Town; D Paris; T Mori; Z Suo; F Crawford; M P Mattson; R A Flavell; M Michael Mullan
Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.
Science (New York, N.Y.) 1999;286(5448):2352-5.
102.
1999
J Tan; T Town; M Saxe; D Paris; Y Wu; M Michael Mullan
Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent
TNF-alpha production that is opposed by TGF-beta 1 and IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6614-21.
103.
1999
T Town; L Abdullah; F Crawford; J Schinka; P I Ordorica; E Francis; P Hughes; R Duara; M
Michael Mullan
Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency.
American journal of medical genetics 1999;88(5):458-61.
104.
1999
T Town; D Paris; T A Parker; A Kundtz; J Tan; R Duara; M Gold; F Crawford; M Michael Mullan
Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G
protein beta3, either independently or interactively with apolipoprotein E.
American journal of medical genetics 1999;88(5):465-8.
105.
1999
J Tan; T Town; Z Suo; Y Wu; S Song; A Kundtz; J Kroeger; J Humphrey; F Crawford; M Michael
Mullan
Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides.
Brain research bulletin 1999;50(2):143-8.
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106.
1999
J Tan; T Town; A Placzek; A Kundtz; H Yu; M Michael Mullan
Bcl-X(L) inhibits apoptosis and necrosis produced by Alzheimer's beta-amyloid1-40 peptide in
PC12 cells.
Neuroscience letters 1999;272(1):5-8.
107.
1999
D L King; G W Arendash; F Crawford; T Sterk; J Menendez; M J Michael Mullan
Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for
Alzheimer's disease.
Behavioural brain research 1999;103(2):145-62.
108.
1999
F Crawford; T Town; M Freeman; J Schinka; M Gold; R Duara; M Michael Mullan
The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control
sample.
Neuroscience letters 1999;270(3):133-6.
109.
1999
G W Arendash; G C Su; F C Crawford; K B Bjugstad; M Michael Mullan
Intravascular beta-amyloid infusion increases blood pressure: implications for a vasoactive
role of beta-amyloid in the pathogenesis of Alzheimer's disease.
Neuroscience letters 1999;268(1):17-20.
110.
1999
J Tan; T Town; D Paris; A Placzek; T Parker; F Crawford; H Yu; J Humphrey; M Michael Mullan
Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis.
Journal of neuroimmunology 1999;97(1-2):77-85.
111.
1999
F Crawford; M Freeman; T Town; D Fallin; M Gold; R Duara; M Michael Mullan
No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic
or population based samples.
Neuroscience letters 1999;266(3):193-6.
112.
1999
D Paris; T Town; T A Parker; J Tan; J Humphrey; F Crawford; M Michael Mullan
Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in
microglia by a cGMP-dependent mechanism.
Experimental neurology 1999;157(1):211-21.
113.
1999
D G Harwood; W W Barker; R L Ownby; M Michael Mullan ; R Duara
Factors associated with depressive symptoms in non-demented community-dwelling elderly.
International journal of geriatric psychiatry 1999;14(5):331-7.
114.
1999
G C Su; G W Arendash; R N Kalaria; K B Bjugstad; M Michael Mullan
Intravascular infusions of soluble beta-amyloid compromise the blood-brain barrier, activate
CNS glial cells and induce peripheral hemorrhage.
Brain research 1999;818(1):105-17.
115.
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1999
D G Harwood; W W Barker; D A Loewenstein; R L Ownby; P St George-Hyslop; M Michael Mullan ; R
Duara
A cross-ethnic analysis of risk factors for AD in white Hispanics and white non-Hispanics.
Neurology 1999;52(3):551-6.
116.
1999
P N Pompl; M J Michael Mullan ; K Bjugstad; G W Arendash
Adaptation of the circular platform spatial memory task for mice: use in detecting cognitive
impairment in the APP(SW) transgenic mouse model for Alzheimer's disease.
Journal of neuroscience methods 1999;87(1):87-95.
117.
1998
Z Suo; J Humphrey; A Kundtz; F Sethi; A Placzek; F Crawford; M Michael Mullan
Soluble Alzheimers beta-amyloid constricts the cerebral vasculature in vivo.
Neuroscience letters 1998;257(2):77-80.
118.
1998
W Barker; D Harwood; R Duara; M Michael Mullan ; D Fallin; P S Hyslop; E Rogaeva; Y Song
The APOE-epsilon4 allele and Alzheimer disease among African Americans, Hispanics, and whites.
JAMA : the journal of the American Medical Association 1998;280(19):1661-2; author reply 1663.
119.
1998
D Paris; T Town; T A Parker; J Humphrey; M Michael Mullan
Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by
Alzheimer's beta-amyloid peptide.
Neuroscience letters 1998;256(2):73-6.
120.
1998
F Crawford; C Soto; Z Suo; C Fang; T Parker; A Sawar; B Frangione; M Michael Mullan
Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational
intermediate.
FEBS letters 1998;436(3):445-8.
121.
1998
Z Suo; J Tan; A Placzek; F Crawford; C Fang; M Michael Mullan
Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the
roles of cytokines and CD40.
Brain research 1998;807(1-2):110-7.
122.
1998
T Town; D Paris; D Fallin; R Duara; W Barker; M Gold; F Crawford; M Michael Mullan
The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease:
independent risk and linkage disequilibrium with the known APOE polymorphism.
Neuroscience letters 1998;252(2):95-8.
123.
1998
R T Zori; J L Gardner; J Zhang; M J Michael Mullan ; R Shah; A R Osborn; H Houlden; M R
Wallace; S Roberts; T P Yang
Newly described form of X-linked arthrogryposis maps to the long arm of the human X chromosome.
American journal of medical genetics 1998;78(5):450-4.
124.
1998
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D Paris; T A Parker; T Town; Z Suo; C Fang; J Humphrey; F Crawford; M Michael Mullan
Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40
peptide.
Experimental neurology 1998;152(1):116-22.
125.
1998
F Crawford; D Fallin; Z Suo; L Abdullah; M Gold; A Gauntlett; R Duara; M Michael Mullan
The butyrylcholinesterase gene is neither independently nor synergistically associated with
late-onset AD in clinic- and community-based populations.
Neuroscience letters 1998;249(2-3):115-8.
126.
1998
F Crawford; Z Suo; C Fang; M Michael Mullan
Characteristics of the in vitro vasoactivity of beta-amyloid peptides.
Experimental neurology 1998;150(1):159-68.
127.
1997
F Crawford; Z Suo; C Fang; A Sawar; G Su; G Arendash; M Michael Mullan
The vasoactivity of A beta peptides.
Annals of the New York Academy of Sciences 1997;826():35-46.
128.
1997
G C Su; G W Arendash; R N Kalaria; M J Michael Mullan
Long-term venous A beta 1-40 infusion in rats causes lung hemorrhage and brain perivascular
gliosis.
Annals of the New York Academy of Sciences 1997;826():440-6.
129.
1997
F Crawford; Z Suo; C Fang; M Michael Mullan
beta-Amyloid peptides and enhancement of vasoconstriction by endothelin-1.
Annals of the New York Academy of Sciences 1997;826():461-2.
130.
1997
D Fallin; A Kundtz; T Town; A C Gauntlett; R Duara; W Barker; F Crawford; M Michael Mullan
No association between the low density lipoprotein receptor-related protein (LRP) gene and
late-onset Alzheimer's disease in a community-based sample.
Neuroscience letters 1997;233(2-3):145-7.
131.
1997
X Cai; D Fallin; J Stanton; P Scibelli; R Duara; F Crawford; M Michael Mullan
APOE is linked to Alzheimer's disease in a large pedigree.
American journal of medical genetics 1997;74(4):365-9.
132.
1997
T Town; D Fallin; F Crawford; S Walsh; R Solomon; M Michael Mullan
Lack of association between the apolipoprotein E epsilon4 allele (APOE epsilon4) and chronic
schizophrenia.
American journal of medical genetics 1997;74(4):451-2.
133.
1997
Z Suo; C Fang; F Crawford; M Michael Mullan
Superoxide free radical and intracellular calcium mediate A beta(1-42) induced endothelial
toxicity.
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Brain research 1997;762(1-2):144-52.
134.
1997
D Fallin; S Reading; J Schinka; J Hoyne; P Scibelli; M Gold; F Crawford; M Michael Mullan
No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's
disease.
American journal of medical genetics 1997;74(2):192-4.
135.
1997
X Cai; J Stanton; D Fallin; J Hoyne; R Duara; M Gold; S Sevush; P Scibelli; F Crawford; M
Michael Mullan
No association between the intronic presenilin-1 polymorphism and Alzheimer's disease in clinic
and population-based samples.
American journal of medical genetics 1997;74(2):202-3.
136.
1997
D Fallin; A C Gauntlett; P Scibelli; X Cai; R Duara; M Gold; F Crawford; M Michael Mullan
No association between the very low density lipoprotein receptor gene and late-onset
Alzheimer's disease nor interaction with the apolipoprotein E gene in population-based and
clinic samples.
Genetic epidemiology 1997;14(3):299-305.
137.
1996
M Michael Mullan ; P Scibelli; R Duara; D Fallin; M Gold; J Schinka; J Hoyne; A Osborne; S
Sevush; F Crawford
Familial and population-based studies of apolipoprotein E and Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;802():16-26.
138.
1996
F Crawford; J Hoyne; X Cai; A Osborne; D Poston; J Zaglul; N Dajani; S Walsh; R Bradley; R
Solomon; et al.
Dopamine DRD2/Cys311 is not associated with chronic schizophrenia.
American journal of medical genetics 1996;67(5):483-4.
139.
1996
T Thomas; G Thomas; C McLendon; T Sutton; M Michael Mullan
beta-Amyloid-mediated vasoactivity and vascular endothelial damage.
Nature 1996;380(6570):168-71.
140.
1995
S E Poduslo; D Riggs; J Schwankhaus; A Osborne; F Crawford; M Michael Mullan
Association of apolipoprotein E but not B with Alzheimer's disease.
Human genetics 1995;96(5):597-600.
141.
1995
F Crawford; J Hoyne; P Diaz; A Osborne; J Dorotheo; D Sheehan; M Michael Mullan
Occurrence of the Cys311 DRD2 variant in a pedigree multiply affected with panic disorder.
American journal of medical genetics 1995;60(4):332-4.
142.
1995
C Bennett; F Crawford; A Osborne; P Diaz; J Hoyne; R Lopez; P Roques; R Duara; M Rossor; M
Michael Mullan
Evidence that the APOE locus influences rate of disease progression in late onset familial
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Alzheimer's Disease but is not causative.
American journal of medical genetics 1995;60(1):1-6.
143.
1995
M Michael Mullan ; C Bennett; C Figueredo; D Hughes; R Mant; M Owen; A Warren; M McInnis; A
Marshall; P Lantos
Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14.
American journal of medical genetics 1995;60(1):44-52.
144.
1994
M Michael Mullan ; F Crawford
The molecular genetics of Alzheimer's disease.
Molecular neurobiology 1994;9(1-3):15-22.
145.
1994
M Michael Mullan ; F Crawford; J Buchanan
Technical feasibility of genetic testing for Alzheimer's disease.
Alzheimer disease and associated disorders 1994;8(2):102-15.
146.
1993
M Michael Mullan ; H Houlden; F Crawford; A Kennedy; P Rogues; M Rossor
Age of onset in familial early onset Alzheimer's disease correlates with genetic aetiology.
American journal of medical genetics 1993;48(3):129-30.
147.
1993
M Michael Mullan ; F Crawford
Genetic and molecular advances in Alzheimer's disease.
Trends in neurosciences 1993;16(10):398-403.
148.
1993
M Michael Mullan ; S Tsuji; T Miki; T Katsuya; S Naruse; K Kaneko; T Shimizu; T Kojima; I
Nakano; T Ogihara
Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val-->Ile mutation
in the amyloid precursor protein gene.
Neurobiology of aging 1993;14(5):407-19.
149.
1993
H Houlden; F Crawford; M Rossor; M Michael Mullan
Screening for the APP codon 670/671 mutations in Alzheimer's disease.
Neuroscience letters 1993;154(1-2):161-2.
150.
1993
H Houlden; M Michael Mullan
Alzheimer's disease aetiology: amyloid and chromosome 14.
British journal of hospital medicine 1993;49(8):535-6.
151.
1993
A M Kennedy; S Newman; A McCaddon; J Ball; P Roques; M Michael Mullan ; J Hardy; M C
Chartier-Harlin; R S Frackowiak; E K Warrington
Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor
protein gene (amyloid precursor protein 717 valine-->glycine).
Brain : a journal of neurology 1993;116 ( Pt 2)():309-24.
152.
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1993
J Brown; S Gydesen; S A Sorensen; A Brun; S Smith; H Houlden; R Twells; M Michael Mullan ; M
Rossor; J Collinge
Genetic characterization of a familial non-specific dementia originating in Jutland, Denmark.
Journal of the neurological sciences 1993;114(2):138-43.
153.
1992
M Michael Mullan ; H Houlden; M Windelspecht; L Fidani; C Lombardi; P Diaz; M Rossor; R Crook;
J Hardy; K Duff
A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal
to the alpha 1-antichymotrypsin gene.
Nature genetics 1992;2(4):340-2.
154.
1992
M Michael Mullan
Familial Alzheimer's disease: second gene locus located.
BMJ (Clinical research ed.) 1992;305(6862):1108-9.
155.
1992
K J Johnson; T Sander; A A Hicks; A van Marle; D Janz; M J Michael Mullan ; B P Riley; M G
Darlison
Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to
distal 5q by linkage analysis.
Genomics 1992;14(3):745-8.
156.
1992
J Hardy; M Michael Mullan
Alzheimer's disease. In search of the soluble.
Nature 1992;359(6393):268-9.
157.
1992
M Michael Mullan ; F Crawford; K Axelman; H Houlden; L Lilius; B Winblad; L Lannfelt
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of
beta-amyloid.
Nature genetics 1992;1(5):345-7.
158.
1992
L Fidani; K Rooke; M C Chartier-Harlin; D Hughes; R Tanzi; M Michael Mullan ; P Roques; M
Rossor; J Hardy; A Goate
Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor
protein gene in familial Alzheimer's disease: identification of a further family with APP717
Val-->Ile.
Human molecular genetics 1992;1(3):165-8.
159.
1992
J Collinge; J Brown; J Hardy; M Michael Mullan ; M N Rossor; H Baker; T J Crow; R Lofthouse; M
Poulter; R Ridley
Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features.
Brain : a journal of neurology 1992;115 ( Pt 3)():687-710.
160.
1992
F Crawford; M C Chartier-Harlin; M Michael Mullan ; J Hardy; A Delacourte; G Arnott
Alzheimer's--a correction.
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Nature 1992;356(6368):390.
161.
1992
P L Lantos; P J Luthert; D Hanger; B H Anderton; M Michael Mullan ; M Rossor
Familial Alzheimer's disease with the amyloid precursor protein position 717 mutation and
sporadic Alzheimer's disease have the same cytoskeletal pathology.
Neuroscience letters 1992;137(2):221-4.
162.
1992
J Hardy; M C Chartier-Harlin; M Michael Mullan
Alzheimer disease: the new agenda.
American journal of human genetics 1992;50(3):648-51.
163.
1992
C L Katona; M Michael Mullan ; C Taylor
Depressive disorders and organic brain disorders: validation of the depressive signs scale.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():169A-170A.
164.
1991
F Crawford; J Hardy; M Michael Mullan ; A Goate; D Hughes; L Fidani; P Roques; M Rossor; M C
Chartier-Harlin
Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with
early onset Alzheimer's disease fails to reveal mutations in the beta-amyloid sequence.
Neuroscience letters 1991;133(1):1-2.
165.
1991
R C Pearson; M Michael Mullan ; J Hardy; P J Harrison
Nicotine intake and Alzheimer's disease.
BMJ (Clinical research ed.) 1991;303(6798):361.
166.
1991
M C Chartier-Harlin; F Crawford; K Hamandi; M Michael Mullan ; A Goate; J Hardy; H Backhovens;
J J Martin; C V Broeckhoven
Screening for the beta-amyloid precursor protein mutation (APP717: Val----Ile) in extended
pedigrees with early onset Alzheimer's disease.
Neuroscience letters 1991;129(1):134-5.
167.
1991
D L Ewins; M N Rossor; J Butler; P K Roques; M J Michael Mullan ; A M McGregor
Association between autoimmune thyroid disease and familial Alzheimer's disease.
Clinical endocrinology 1991;35(1):93-6.
168.
1991
C M van Duijn; C van Broeckhoven; J A Hardy; A M Goate; M N Rossor; A Vandenberghe; J J Martin;
A Hofman; M J Michael Mullan
Evidence for allelic heterogeneity in familial early-onset Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1991;158():471-4.
169.
1991
M Michael Mullan
A genetic defect causing Alzheimer's disease.
British journal of hospital medicine 1991;45(3):131.
170.
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1991
A Goate; M C Chartier-Harlin; M Michael Mullan ; J Brown; F Crawford; L Fidani; L Giuffra; A
Haynes; N Irving; L James
Segregation of a missense mutation in the amyloid precursor protein gene with familial
Alzheimer's disease.
Nature 1991;349(6311):704-6.
171.
1991
M J Michael Mullan ; L Giuffra; J A Hardy; I Ovenstone; A R Haynes; L A James; R Williamson; P
J Newton; M J Owen; P Roques
Clinical and pathologic features of chromosome 21-linked familial Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;640():177-80.
172.
1991
J Brown; S Smith; A Brun; J Collinge; S Gydesen; J Hardy; M Michael Mullan ; A Goate
Genetic characterization of a novel familial dementia.
Annals of the New York Academy of Sciences 1991;640():181-3.
173.
1990
P H St George-Hyslop; J L Haines; L A Farrer; R Polinsky; C Van Broeckhoven; A Goate; D R
McLachlan; H Orr; A C Bruni; S Sorbi; et al.
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.
Nature 1990;347(6289):194-7.
174.
1990
J Clinton; P L Lantos; M Rossor; M Michael Mullan ; G W Roberts
Immunocytochemical confirmation of prion protein.
Lancet 1990;336(8713):515.
175.
1990
J Collinge; F Owen; M Poulter; M Leach; T J Crow; M N Rossor; J Hardy; M J Michael Mullan ; I
Janota; P L Lantos
Prion dementia without characteristic pathology.
Lancet 1990;336(8706):7-9.
176.
1990
S Hodgkinson; M J Michael Mullan ; H M Gurling
The role of genetic factors in the etiology of the affective disorders.
Behavior genetics 1990;20(2):235-50.
177.
1990
L A Farrer; R H Myers; L A Cupples; P H St George-Hyslop; T D Bird; M N Rossor; M J Michael
Mullan ; R Polinsky; L Nee; L Heston
Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for
heterogeneity.
Neurology 1990;40(3 Pt 1):395-403.
178.
1990
A M Goate; J A Hardy; M J Owen; A Haynes; L James; M Farrall; M J Michael Mullan ; P Roques; M
N Rossor
Genetics of Alzheimer's disease.
Advances in neurology 1990;51():197-8.
179.
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1990
M J Owen; M J Michael Mullan
Molecular genetic studies of manic-depression and schizophrenia.
Trends in neurosciences 1990;13(1):29-31.
180.
1989
J A Hardy; A M Goate; M J Owen; M J Michael Mullan ; M N Rossor; R C Pearson
Modelling the occurrence and pathology of Alzheimer's disease.
Neurobiology of aging 1989;10(5):429-31; discussion 446-8.
181.
1989
M J Michael Mullan ; R M Murray
The impact of molecular genetics on our understanding of the psychoses.
The British journal of psychiatry : the journal of mental science 1989;154():591-5.
182.
1989
A M Goate; A R Haynes; M J Owen; M Farrall; L A James; L Y Lai; M J Michael Mullan ; P Roques;
M N Rossor; R Williamson
Predisposing locus for Alzheimer's disease on chromosome 21.
Lancet 1989;1(8634):352-5.
183.
1989
J A Hardy; M J Owen; A M Goate; L A James; A R Haynes; M N Rossor; P Roques; M J Michael Mullan
Molecular genetics of Alzheimer's disease.
Biochemical Society transactions 1989;17(1):75-6.
184.
1986
M J Michael Mullan ; H M Gurling; B E Oppenheim; R M Murray
The relationship between alcoholism and neurosis: evidence from a twin study.
The British journal of psychiatry : the journal of mental science 1986;148():435-41.
-21-