dr. d. y. patil uniteh soietys dr. d. y. patil institute ... · 3. dharmesh r. chejara, mostafa...

I AFFILIATED TO SAVITRIBAI PHULE PUNE UNIVERSITY. UNIVERSITY ID NO. - PU / PN / PHARM / 104 / 94 I

I APPROVED BY AICTE & RECOGNIZED BY PCI I NAAC ACCREDITED I NBA RE-ACCREDITED I ISO 9001:2008 CERTIFIED I

DR. D. Y. PATIL UNITECH SOCIETY’S

DR. D. Y. PATIL INSTITUTE OF PHARMACEUTICAL SCIENCES AND RESEARCH SANT TUKARAM NAGAR, PIMPRI, PUNE - 411 018 (MH) INDIA

● www.pharmacy.dypvp.edu.in ● [email protected] ●

DR. RAVINDRA V. BADHE

ASSOCIATE PROFESSOR – DEPARTMENT OF PHARMACEUTICAL CHEMISTRY

eMail : [email protected]

Qualification : M. Pharm., Ph.D.

PROFESSIONAL EXPERIENCE: 1. Worked as NRF Postdoctoral Research Fellow at Department of Pharmacy and Pharmacology,

Medical School, University of Witwatersrand, Johannesburg, RSA. (July. 2014 - June. 2016)

2. Worked as Assistant Professor from August 2006 to June 2014 in Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune – 411018. (August, 2006 - Till date)

3. Worked as Lecturer from September 2005 to July 2006 in Modern College of Pharmacy, Yamunanagar, Nigdi, Pune – 411044. (Nov., 2005 - July, 2006)

TOTAL EXPERIENCE

Teaching : 12.8 years

Research : 7 years

M. PHARM. STUDENTS GUIDED : 23 INSTITUTIONAL AND ADMINISTRATIVE RESPONSIBILITIES :

R & D committee Incharge

CORE COMPETENCY AREAS :

Regenerative medicine, Biodegradable 3D scaffold designing, Multilayered scaffold development, Bioreactor design, Tissue engineering, Biopharmaceutical production, purification and characterization, Oral protein delivery, Biodegradable nano-particle development.

ACHIEVEMENTS / AWARDS :

1. My research project received Second Prize - National level Anveshan - 2016 and First Prize - State level Avishkar – 2016 scientific research competition for the project “Rib cage plaster” held at Annamalai University, Tamil Nadu, India and The Swami Ramanand Teerth Marathwada University, Nanded. M.S., India respectively.

2. NRF Postdoctoral Fellow - University of Witwatersrand, Johannesburg, RSA






3. Received Second Prize - State Level – Ph.D. student category for the project “Biodegradable 3D bone Scaffold and new bioreactor design for bone regeneration and reconstructive surgery” at Avishkar – 2011 scientific research competition. Shivaji University, Kolhapur. M.S., India.

4. Received Second Prize - State Level – Ph.D. student category for the project “Design and functioning of new flow chamber bioreactor for skin tissue engineering applications” at Avishkar – 2010 scientific research competition. Maharashtra University of Health Science, Nashik. M.S., India.

PUBLICATIONS : 1. Ravindra V. Badhe, Pradeep Kumar, Yahya E. Choonara, Thashree Marimuthu, Lisa C. du Toit, Divya

Bijukumar, Dharmesh R. Chejara, Mostafa Mabrouk and Viness Pillay. Customized Peptide Biomaterial Synthesis via an Environment-Reliant Auto-Programmer Stigmergic Approach. Materials. 2018, 11, 609; doi:10.3390/ma11040609. (MDPI/IF - 2.613)

2. A. Zardad, M. Mabrouk, T. Marimuthu, L.C. du Toit, P. Kumar, Y.E. Choonara, P.P.D. Kondiah, R.V. Badhe, D.R. Chejara, V. Pillay. Synthesis and biocompatibility of dual-responsive thermosonic injectable organogels based on crosslinked N-(isopropyl acrylamide) for tumour microenvironment targeting. Materials Science & Engineering C. 2018, 90, 148-158. (Elsevier/IF - 5.08)

3. Dharmesh R. Chejara, Mostafa Mabrouk, Pradeep Kumar, Yahya E. Choonara, Pierre P. D. Kondiah, Ravindra V. Badhe, Lisa C. du Toit, Divya Bijukumar and Viness Pillay. Synthesis and Evaluation of a Sodium Alginate-4-Aminosalicylic Acid Based Microporous Hydrogel for Potential Viscosupplementation for Joint Injuries and Arthritis-Induced Conditions. Marine Drugs. 2017, 15(8), E257; doi:10.3390/md15080257. (MDPI/IF - 4.37)

4. Ravindra V. Badhe, Divya Bijukumar, Dharmesh R. Chejara, Mostafa Mabrouk, Yahya E. Choonara, Pradeep Kumar, Lisa C. du Toit, Pierre P.D. Kondiah and Viness Pillay. A Composite Chitosan-Gelatin Bi-Layered, Biomimetic Macroporous Scaffold for Blood Vessel Tissue Engineering. Carbohydrate Polymers. 2017, 3, 1215-1225. (Elsevier/IF - 5.15)

5. Ravindra V. Badhe, Pradeep Kumar, Yahya E. Choonara, Thashree Marimuthu, Olufemi D. Akilo, Pierre P.D. Kondiah, Lisa C. du Toit, Viness Pillay. Induction of Creep Crack Morphology in Iron Oxide Microparticles: An Outcome of the Common-Ion Effect. Materials Letters. 2017, 188, 417-422. (Elsevier/IF - 2.68)

6. Dharmesh R. Chejara, Mostafa Mabrouk, Ravindra V. Badhe, Jameel A.S. Mulla, Pradeep Kumar, Yahya E. Choonara, Lisa C. du Toit, Viness Pillay. A bio-injectable algin-aminocaproic acid thixogel with tri-stimuli responsiveness. Carbohydrate Polymers. 2016, 135(1), 324-333. (Elsevier/IF - 5.15)

7. Mostafa Mabrouk, Jameel A. S. Mulla, Pradeep Kumar, Dharmesh R. Chejara, Ravindra V. Badhe, Yahya E. Choonara, Lisa C. du Toit, and Viness Pillay. Intestinal Targeting of Ganciclovir Release Employing a Novel HEC-PAA Blended Lyomatrix. AAPS PharmSciTech. 2016 17(5), 1120-1130. (Springer/IF - 2.451)

8. Ravindra V. Badhe, Rabindra K. Nanda, Dharmesh R. Chejara, Yahya E. Choonara, Pradeep Kumar, Lisa C. du Toit and Viness Pillay. Microwave-assisted facile synthesis of a new tri-block chitosan






conjugate with improved mucoadhesion. Carbohydrate Polymer. 2015, 130, 213-221. (Elsevier/IF - 5.15)

9. Mostafa Mabrouk, Divya Bijukumar, Jameel A S Mulla, Dharmesh R Chejara, Ravindra V Badhe, Yahya E Choonara, Pradeep Kumar, Lisa C Du Toit, Viness Pillay. Enhancement of the biomineralization and cellular adhesivity of polycaprolactone-based hollow porous microspheres via dopamine bio-activation for tissue engineering applications. Materials Letters. 2015, 161, 503-507. (Elsevier/IF - 2.68)

10. Mostafa Mabrouk, Dharmesh R Chejara, Jameel A Mulla, Ravindra Badhe, Yahya E Choonara, Pradeep Kumar, Lisa C du Toit and Viness Pillay. Design of a novel crosslinked HEC-PAA porous hydrogel composite for dissolution rate and solubility enhancement of Efavirenz. International Journal of Pharmaceutics. 2015, 490, 429-437. (Elsevier/IF - 4.22)

11. Badhe R. V., Nanda R. K. Design and Functioning of New Flow Chamber Bioreactor for Skin Tissue Engineering Applications. Journal of Biomaterials and Tissue Engineering, 2014, 4(4), 269-273. (American Scientific Publishers/IF - 0.781)

12. Badhe R.V., Chintamani R. C., Bhujbal M. Patil P., Badhe S. R., Nanda R.K., Shirolkar S V. Spectrophotometric Bioassay Method for Urokinase. Journal of Pharmacological and Toxicological Methods, 2010, 61 (3), 343-345. (Elsevier/IF - 2.430)

13. Thomas A. B., Sharma P. A., Tupe P. N., Badhe R.V., Nanda R. K., Kothapalli L. P., Paradkar O. D., Banerjee A. G. Green route synthesis of 4-thiazolidinone analogs of isonicotinic acid hydrazide. Green Chemistry Letters and Reviews, 2011, 4(3), 211-217. (Taylor & Francis/IF - 3.364)

14. Thomas A. B., Sharma P. A., Tupe P. N., Badhe R.V., Nanda R. K., Kothapalli L. P., Paradkar O. D., Banerjee A. G. Hamane S. Eco-friendly synthesis of 2-azetidinone analogs of isonicotinic acid hydrazide. Green Chemistry Letters and Reviews, 2010; 3(4), 293-300. (Taylor & Francis/IF - 3.364).

15. Badhe R.V., Bhujbal M. Patil P., Badhe S. R., Nanda R.K. Production of Serratiopeptidase from serratia marcescens ATCC 13880. Hindustan Antibiotics Bulletin, 2009, 51, 17-23. (Hindustan Antibiotics/IF - 0.455)

16. Badhe R.V., Harer S. L., Nandan R. K, Badhe S. R., Jangam S.J., Purification and Partial Characterization of thermostable serine Alkaline Protease from a newly isolated Bacillus species HSRB08 from Hotspring. Hindustan Antibiotics Bulletin, 2009, 51, 9-16. (Hindustan Antibiotics/IF - 0.455)

17. Thomas A.B., Tupe P.N., Badhe R.V., Nanda R. K., Kothapalli L. P., Paradkar O. D., Green route synthesis of Schiff’s bases of isonicotinic acid hydrazide. Green Chemistry Letter and Reviews. 2009, 2(1), 23-27. . (Taylor & Francis/IF - 3.364).

18. Badhe R.V., Thomas A.B., Harer S., Deshpande A.D. Salvi N.C., Waghmare A.B., Intraspecific variation in protein pattern of the Red scorpion (Mesobuthus tamulus, coconsis, pocock) venom of Western and Southern India. JVATiTD, 2006, 12 (4), 612-619. (BioMedCentral/IF - 1.746)

https://www.researchgate.net/researcher/2081617858_Mostafa_Mabrouk

https://www.researchgate.net/researcher/2052307329_Divya_Bijukumar

https://www.researchgate.net/researcher/2081622662_Jameel_A_S_Mulla

https://www.researchgate.net/researcher/54260081_Dharmesh_R_Chejara

https://www.researchgate.net/researcher/38155082_Yahya_E_Choonara

https://www.researchgate.net/researcher/39534927_Pradeep_Kumar

https://www.researchgate.net/researcher/84458237_Lisa_C_Du_Toit

https://www.researchgate.net/researcher/39051845_Viness_Pillay






19. Badhe R.V. , Thomas A.B., Harer S., Deshpande A.D. Salvi N.C., Waghmare A.B., The action of red scorpion (Mesobuthus tamulus, Coconsis, pocock) venom and its isolated protein fractions on blood serum sodium levels. JVATiTD, 2007, 13 (1), 82-93. (BioMedCentral/IF - 1.746)

20. Badhe R. V., Badhe S. R., Bhujbal M. N., Nanda R. K., Shirolkar S. V. Urokinase: isolation, purification, characterization, new spectrophotometric bioassay method and in-vitro blood clot dissolving activity from cow urine. International Journal of Ayurvedic Medicine, 2013, 4(1), 17-26.

21. Dangre P., Badhe R. V., Shirolkar S., Dhole S. Formulation, Evaluation and Optimization of Fungal Alpha Amylase Loaded Alginate Bead. Journal of Advanced Pharmaceutical Research. 2013, 4(3), 74- 85.

22. Badhe R.V., Badhe S. R., Jangam S. J., Rane P., Thomas A. B., Antibacterial, antifungal, pisicidal and cardiac activities of Derris heyneana (Wight & Arm.) Benth. Indian Journal of Natural Products and Resources, 2010, 1(3), 287-290.

23. Badhe S. R., Badhe R. V., Ghaisas M. M. Evaluations of antidepressant activity of Anacyclus pyrethrum root extract. International Journal of Green Pharmacy. 2010, 4(2), 79-82.

24. Thomas A. B. Badhe R. V., Yadav R. Kothapalle L., Antihyperlipedemic effect of Derris trifoliata Lour in triton induced hyper lipedemia in rats Journal of Pharmacy and chemistry, 2008, 2(4), 177-181.

25. Badhe R.V., Thomas A.B., Deshpande A.D., Stability Indicating HPLC method for the determination of Mizolastine in bulk drug and pharmaceutical dosage form. Indian Drugs, 43 (3) March 2006, 199-204.

BOOKS / CHAPTERS IN BOOKS 1. Ravindra V. Badhe, Dharmesh R. Chejara, Pradeep Kumar, Lisa C. du Toit, Yahya E. Choonara and

Viness Pillay, ' Neurodegenerative disease conditions and genomic treatment for better health' in Genomics-Driven Healthcare: Trends in Disease Prevention and Treatment, Ed. by Y. Pathak. Springer International Publishing, Singapore, Chapter 15, 1st ed. 2018 (ISBN: 978-981-10-7505-6).

2. Dharmesh R. Chejara, Ravindra V. Badhe, Pradeep Kumar, Lisa C. du Toit, Yahya E. Choonara and Viness Pillay, 'Rethinking drug discovery and targeting after the genomic revolution' in Genomics-Driven Healthcare: Trends in Disease Prevention and Treatment, Ed. by Y. Pathak. Springer International Publishing, Singapore, Chapter 1, 1st ed. 2018 (ISBN: 978-981-10-7505-6).

PROJECTS HANDLED/GRANTS RECEIVED : 1. Project title: “Immobilization of whole-cell and therapeutic protein” Sponsored project by “Board of

College and University Development (BCUD)”, University of Pune. (PI –Ravindra Badhe) (Duration – 2009 – 2012) (Amount sancetioned: Rs. 3,00,000/-).

2. Project title: “Production of Urokinase enzyme by using mammalian cell culture technique” Sponsored project by “All India Council for Technical Education (AICTE)” under the “Research Promotion Scheme” of the Council. (Project Supervisor - Dr. Satish Shirolkar, Head, Department of






Pharmaceutics, Dr. D. Y. Patil IPSR, Pimpri) (Duration – 2006-2009) (Amount sancetioned: Rs. 9,00,000/-).

SEMINARS / WORKSHOPS / CONFERENCES ATTENDED :

1. R. V. Badhe, V. Pillay, Enteric-Coated Alginate Matrix with Immobilized Modified Chitosan Nanoparticles for Oral Delivery of Urokinase, APSSA/SAAPI Conference 2015, Johannesburg, RSA, 17 -18 Sep., 2015.

2. R. V. Badhe, R. K. Nanda, D. R. Chejara, Y. E. Choonara., V. Pillay, Modified, Urokinase-Loaded, Chitosan Nanoparticles Immobilized In an Enteric Coated Alginate Matrix For Oral Delivery, APS 6th International PharmSci Conference 2015, Nottingham, UK, 7-9 Sept., 2015.

3. R. V. Badhe, One day workshop for designing/framing syllabus of University of Pune for semester III and Iv of second Year B. Pharm. (Pattern 2013) for the subject of Pharmaceutical Chemistry at Maharashtra Institute of Pharmacy, Pune on 14th March, 2014.

4. R. V. Badhe, Three day 4th National workshop on Insilico Drug Discovery by RASA life sciences at Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune on 7th to 9th March, 2014.

5. R. V. Badhe, Resource Person in One day Orientation Workshop - Avishkar - 2013 organized by BCUD, University of Pune at Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune on 10th December, 2013.

6. R. V. Badhe, One day seminar on Understanding the credit and GPA system at Modern College of Pharmacy, Yamunanagar, Nigdi, Pune on 21st October, 2013.

7. R. V. Badhe, Two day National level seminar on Current Research on Advanced Drug Design and Development : A Medicinal Chemistry Approach at Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune on 27th and 28th September, 2013.

8. R. V. Badhe, Two day National level seminar on Current Research on Application of Nanotechnology in Medicine at Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune on 18th and 19th October, 2013.

9. R. V. Badhe, One day workshop on Intellectual property rights for Pharma. professionals. Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune on 15th May, 2013.

10. R. V. Badhe, “Bi-Layered Artificial Skin for Burn Wound Therapeutics” Participation in 7th Maharashtra State Inter University Research Convention - Avishkar - 2012-2013 at Dr. Babasaheb Sawant Konkan Krishi Vidyapeeth, Dapoli, Ratnagiri, M.S. on 7th to 9th January, 2013.

FACULTY DEVELOPMENT PROGRAMME

Participated in AICTE Sponsored two weeks faculty development programme on ‘Role of industry and institute interface for academic excellence in pharmacy’ organized by Padm. Dr. D. Y. Patil College of Pharmacy, Akurdi, Pune 411044 (18/11/2013 - 02/12/2013)






CONSULTANCY AND TRAINING PROVIDED :

Provide Consultancy and Training on Bioreactor handling and SDS-PAGE.

Worked as a resource person for AVISHKAR-2013 workshop organized by University of Pune for shortlisted students and teachers at University of Pune.

Worked as Project Evaluator for University level AVISHKAR at University of Pune.

PROFESSIONAL AFFILIATIONS: 1. Toxinological Society of India (TSI) – Registration No. TSI/LM/29

2. Member of Association of Pharmacy Teachers of India (APTI) Registration No. MA/LM – 1077.

3. Registered Pharmacist (Maharashtra) PCI-India. 70795

dr. d. y. patil uniteh soietys dr. d. y. patil institute ... · 3. dharmesh r. chejara, mostafa...

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