Download - YAWS PIAN BUBAS FRAMBOESIA
![Page 1: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/1.jpg)
YAWS1. PIAN2. BUBAS3. FRAMBOESIA
![Page 2: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/2.jpg)
Yaws and its relativesare caused by spirochete bacteria
Treponema
![Page 3: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/3.jpg)
• Contagious , non venereal treponemal infection. • No cardiovascular or neurological abnormalities
![Page 4: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/4.jpg)
Yaws is typically found in tropical areas of Africa, South America, and Asia
![Page 5: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/5.jpg)
Between 1950 and 1970, WHO and UNICEF led a campaign to treat people in 46 countries
![Page 6: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/6.jpg)
It worked, but these diseases now receive little attention
![Page 7: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/7.jpg)
Caused by Treponema pertenue . Reservoir of infection – Man Age - It affect children < 15 years [peak
incidence 6-10 years]. Immunity – no natural immunity. Provides
partial immunity to veneral syphilis.
![Page 8: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/8.jpg)
ENVIRONMENTAL FACTORS
• Climate – endemic in warm and humid conditions
• Social factors scanty clothingPoor personal cleanlinessOvercrowdingBad housingLow standard of livingAbsence of soap
![Page 9: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/9.jpg)
MODE OF TRANSMISSION
• Direct contact• Fomites• Vector
INCUBATION PERIOD 3 to 5 weeks
![Page 10: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/10.jpg)
The endemic treponematoses are mainly transmitted by human-to-human contact
![Page 11: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/11.jpg)
CLASSIFICATION
• Primary stage …..lesion at site of inoculation. • Secondary stage ….multiple skin lesion. • Latent stage …..no symptom but skin lesion can
relapse. • Tertiary ….bone , joint & soft tissue deformality
![Page 12: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/12.jpg)
OTHER CASSIFICATION
• Early----: primary & secondary { contagious skin lesion }.
• Late -----: tertiary (not contagious).
![Page 13: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/13.jpg)
CLINICAL PRESENTATION Primary lesion called….. mother yaw.[IP 9-90 days]. 1ry papule---enlarge → papilloma {resolve
spontaneously after 3-6 months }. 2ry may occur near the 1ry or elsewhere on the body
{last for more than 6 months } Macule , papules , nodules ,and hyperkeratotic lesion in
palms & soles { CRAB YAWS } ,lesions may ulcerate. Saber shin due to chronic untreated osteoperiostitis. Pt with late yaws → juxtaarticular nodules → gangosa [
rhinopharyngitis mutilans ]
![Page 14: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/14.jpg)
The first sign of yaws is a primary lesion known as a “mother yaw”
![Page 15: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/15.jpg)
Without treatment, secondary widespread lesions form
![Page 16: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/16.jpg)
After years without treatment, larger problems may develop
Gangosa Saber shin / tibia
![Page 17: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/17.jpg)
INVESTIGATIONS
Diagnosis on clinical findings. Non treponema test:VDRL. Positive in all
stages except early lesions . Dark-field examination ….. + ve . Biopsy.
![Page 18: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/18.jpg)
These diseases can be diagnosed in two ways
Dark field microscopy
Serological Tests
![Page 19: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/19.jpg)
MANAGEMENT
Benzathine penicillin ( penicillin G ) 1.2 million units IM once
Penicillin V for 7-10 days.[ for 1ry , 2ry &latent].Tetracyclin 1-2 g\ day for 7-14 days.[tertiary] Erythromycin [tertiary]. Doxycycline 200mg 1 st ,100 mg\day for 7-14
days.[tertiary].
![Page 20: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/20.jpg)
Benzathine penicillin is the main drug of choice for treatment
![Page 21: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/21.jpg)
CONTROL1. Survey2. Treatment
Total mass treatment ( more than 10% prevalence)Juvenile mass treatment ( 5% to 10 %)selective mass treatment (less than 5 %)
3. Resurvey and treatment ( every 6 to 12 months)4. Surveillance5. Environmental improvement6. Resurgence of yaws7. Evaluation
![Page 22: YAWS PIAN BUBAS FRAMBOESIA](https://reader034.vdocuments.us/reader034/viewer/2022051007/5a4d1b217f8b9ab0599955f2/html5/thumbnails/22.jpg)