Vertebrate Embryonic Patterning 7

Left-Right Axis Polarity

Asymmetric Gene Expression Establishes Left-Right AxisChick

Mouse

Shh Induces Nodal

nodal expression

Asymmetric Expression at the Node Shh Act RIIa

Asymmetric Expression in Lateral Plate Mesoderm

caronte nodal pitx-2

lateral plate mesoderm

heart tubeA&C ventral views, B dorsal view

Nodal Expression in Lateral Plate of Mouse Embryo

nodal

situs inversus viscerum (iv)

mutant

Asymmetries in Vertebrate Organogenesis