UVEA Choroidal melanomaReferral: Urgent to normal depending on characteristics*

● The annual malignant transformation rate of choroidal nevi in Caucasians is estimated to be one in 8845, this drops to one in 3664 for ages 80-84 years old (Chien et al., 2017)

● There are a number of risk factors for such melanoma trans-formations, the most important of which appears to be chorodial thickness of > 2 mm.

● Carol Shields at Wills Eye Hospital (USA) has done a lot of work in this area. She identifies 5 factors associated with risk of growth of small choroidal lesions:1. tumor thickness greater than 2.0 mm 2. subretinal fluid3. visual symptoms4. orange pigment5. posterior tumor margin touching the disc

These five factors can be easily rememberd with the mnemonic: To Find Small Ocular Melanoma(= Thickness, Fluid, Symptoms, Orange pigment, Optic Disc Margin)

● Nevi with three or more risk factors demonstrate malignant transformation in 50% of cases over 5 years (Chien et al., 2017)

These images were originally published in the Retina Image Bank. Henry J. Kaplan, MD Mayo Clinic Jacksonville, Florida. Year 2013; Image Numbers 7799 and 10386. © the American Society of Retina Specialists. Video�

*The

refe

rral

adv

ice

in th

e at

las s

houl

d be

use

d as

a g

ener

al g

uide

line

and

the

opto

met

ry a

tlas d

oes n

ot e

stab

lish

a st

anda

rd o

f op

tom

etric

car

e an

d sp

ecifi

c ou

tcom

es a

re n

ot g

uara

ntee

d. P

leas

e re

ad fu

ll de

tails

on

gree

n-cl

ub.e

u/ne

ws/

opto

met

ry-a

tlas

/