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Tumor Board: Multidisciplinary Approach to Rare Breast Lesions
Moderator: Aysegul A. Sahin, MD
Panelists:
Bruce Haffty
Kelly K. Hunt
Liane Philpotts
Kalliopi P. Siziopikou
Debu Tripathy
ASBD-SIS 2014 World Congress on Breast Healthcare
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• 48-year old female presents with a palpable breast mass.
• She has a strong family history of breast cancer.
• Physical examination reveals a 2.5 cm mass, not fixed to overlying skin or underlying chest wall.
Case #1
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Case #1
Courtesy of Dr. W. Yang
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Case #1
Courtesy of Dr. W. Yang
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Case #1
CNB reveals spindle cell malignant neoplasm
cytokeratin
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Case #2
48-year old woman had a stereotactic CNB of pleomorphic calcifications identified on screening mammogram.
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Case #2
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Dx: Pleomorphic Lobular Carcinoma in situ
Case #2
E-cadherin
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Case #2
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Case #3
• 68-year old woman with history of myocardial infarct was found to have punctate calcifications associated with 1 cm left breast density on annual screening mammogram.
• Stereotactic CNB revealed invasive ductal carcinoma grade 2, ER+, PR+, Her2 -.
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Case #3
• Segmental resection and SLN biopsy was performed.
• 1.1 cm IDC, grade 2, no LVI
• Margins free (closest margin 0.5 cm)