![Page 1: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/1.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Translational Research: Tracking the (not so straight) Path of Translational Research
Christie Drew & Kristi PettiboneProgram Analysis Branch
![Page 2: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/2.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
NIEHS Program Analysis Branch
• Short and long term program evaluation & portfolio analysis
• Information technology to support analysis and strategic planning
• Communicate research impact
Christie DrewBranch Chief
Joel CollinsonAdministrative
Support
Helena KennedyProgram Analyst
Kristi PettiboneEvaluator
Steven TuyishimePresidential
Management Fellow
Elizabeth RubenIT Liaison, Analyst
Sarah LuginbuhlAnalyst
CareerTrac
![Page 3: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/3.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Communicating research results and impact
• Congressional Justification, Inquiries, Testimony
• Presentations by Dr. Birnbaum and Senior NIEHS Staff (SOT, Council, Town Hall Meetings, Stakeholders)
• Reporters/Requests from the Communications Office
• Extramural Papersof the Month –http://www.niehs.nih.gov/news/newsletter/
• Program evaluations → Strategic Planning for Funding Announcement Opportunities
![Page 4: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/4.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Building Blocks to Measuring Impact
• All publications should cite your grant number
• Best format: R01 ES 123456
• Tell us about it in your progress reports
• PEPH Metrics Manual can help you measure successwww.niehs.nih.gov/pephmetrics
Publications
Progress Reports
Special Data
Collection
![Page 5: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/5.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
National Institutes of Health • U.S. Department of Health and Human Services
![Page 6: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/6.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Evolution of Translational Research Frameworks
Khoury et al. 2007
![Page 7: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/7.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
National Center for Advancing Translational SciencesTranslational Science Spectrum
![Page 8: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/8.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Overview of Framework…
![Page 9: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/9.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Fundamental Questions
Asking: • What is it?• What is it doing?• How does it do
that and what else is going on?
![Page 10: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/10.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
2
1
Population (Human)
In vivo (Mouse)
Example of Movement Around the Ring
Observation (What is happening?)
Understanding(How does it work?)
Translation
Harvard UniversityCore Center
![Page 11: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/11.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Application and Synthesis
testing in a
structured and
predictable setting
to gain deeper
understanding of a
process or a
particular effect
![Page 12: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/12.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Implementation and Adjustment
testing in real
world settings
and adjusting
for differences
in settings and
populations
![Page 13: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/13.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Moving established and
validated ideas into
common practice to
affect change among a
broader population
Practice
![Page 14: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/14.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Impact
Assess the impact of a
practice, guideline,
or policy
![Page 15: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/15.jpg)
Full Framework
![Page 16: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/16.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Benefits of the Framework
• Clearly communicate a concept of translational research
• Provide a storytelling tool or structure for grantees
• Provide a path for researchers to see where research might go
• Provide a strategy for understanding, assessing and categorizing translational research
• Enable us to track movement of research through translational spectrum over long periods of time
• Ability to use framework as an evaluation tool
• Enable program staff to actively manage translational bridges
![Page 17: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/17.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
![Page 18: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/18.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
![Page 19: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/19.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
Team Science & Interdisciplinary Work
![Page 20: Translational Research: Tracking the (Not So Straight ...€¦ · •Short and long term program evaluation & portfolio analysis •Information technology to support analysis and](https://reader035.vdocuments.us/reader035/viewer/2022081612/5f2307b4a00b725da23c3957/html5/thumbnails/20.jpg)
National Institutes of HealthU.S. Department of Health and Human Services
NIEHS Mission:Discover how the environment affects people in order to promote healthier lives.
Not all research will be translational!