Tissue EngineeringReagan Coats

Organ Transplantation

In the United States, the number of patients on the waiting list rose to over 95,000 in the year 2006, with the number of patient deaths reaching 6,300.

Tissue Engineering

•Cells seeded onto scaffold to create appropriate environment for regeneration of tissues and organs

Scaffolds• Criterion• Biocompatible

• Biodegradable

• Mechanical Properties

• Architecture

• Materials• Ceramics

• Synthetic Polymers

• Natural Polymers

Dr. Paolo Macchiarini

•First successful synthetic organ transplantation

Synthetic Trachea Implantations

References

• http://www.rpi.edu/dept/chem-eng/Biotech-Environ/Projects00/tissue/What%20is%20Tissue%20Engineering.htm

• http://www.nibib.nih.gov/science-education/science-topics/tissue-engineering-and-regenerative-medicine

• http://www.smita-iitd.com/research-highlights/tissue-engineering

• http://www.tankonyvtar.hu/en/tartalom/tamop425/0011_1A_3D_en_book/ch01.html

• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475566/

• http://www.harvardapparatusregen.com/index.php/about/clinical-experience/