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www.ebmt.org#EBMT2014
The EBMT, 40 years improving and
promoting HSCT.
Activity Report 2010 - 2014
Alejandro Madrigal, EBMT President
Milan, Italy
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1. President’s Activity Report – Alejandro Madrigal
2. Treasurer’s Activity Report – Fred Falkenburg
3. Secretary’s Report – Anna Sureda
4. Election Results – Anna Sureda
Agenda
#EBMT2014
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33#EBMT2014
About the EBMT
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44
Looking back 2010 - 2014
Our Vision
• Increase the level of science across the organisation with a
view to advancing clinical practice;
• Improve the governance structure for effective and
accountable implementation of the Mission;
• Maximize the resources to strengthen the activities of the
Society.
#EBMT2014
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55
• Global Productivity
• New Clinical Trials
• The Registry Upgrade Project
• Consolidation of Society
#EBMT2014
Looking back 2010 - 2014
Achievements
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Transparency, Accountability and Sustainability
#EBMT2014
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Science
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88
• 150 manuscripts published in peer-review journals with
• 1000 accumulative impact factor
• 50 educational events
• 10 initiated prospective Clinical Trials
• More than 100 retrospective studies performed
• 470,000 registered transplants
Working Party Achievements
#EBMT2014
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• New protocols signed: RACE and MCV:
– RACE: A prospective Randomized multicenter study comparing horse
Antithymocyte globuline (hATG) + Cyclosporine A (CsA) with or without Eltrombopag as front-line therapy for severe aplastic anemia patients
– CMV: A phase III Randomized, Placebo-controlled Clinical Trial to
Evaluate the Safety and Efficacy of MK-8228 (Letermovir) for the Prevention of Clinically Significant Human Cytomegalovirus (CMV) Infection in adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients.
Clinical Trials
#EBMT2014
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1010
• 2012 annual survey: – 661 teams from 48 countries reported their number of
transplants– Report based on 37,818 transplants and 33,678 patients
• In the last 10 years, use of allogeneic HSCT increases more than autologous.– Leukemias: 32%
– Lymphoid Neoplasias: 57%
– Solid Tumours: 5%
– Non-malignant disorders: 6%
– Autologous HSCT for Autoimmune diseases has increased by 50%
2012 Activity Survey
#EBMT2014
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Registry Upgrade Project
#EBMT2014
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Registry Upgrade Project
#EBMT2014
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Education
#EBMT2014
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1414
• 13 educational events
• Organisation of working party educational meetings in 5 different cities
• Collaboration with ESH around the EBMT Handbookon Haematopoietic Stem Cell Transplantation
• Successful edition of the 17th Joint ESH-EBMTTraining Course in Siracuse, Italy.
Education
#EBMT2014
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1515
18th ESH-EBMT Training Course on
Haemopoietic Stem Cell Transplantation
Education
#EBMT2014
May 08 – May 10 2014
Vienna, Austria
Chairs : J. Apperley, E. Carreras, E. Gluckman, T.
Masszi
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1616
• 41st Annual Meeting of the EBMT
– 22 - 25 March 2015Istanbul, TurkeyVenue: Istanbul Congress Center (ICC)
– Congress Co-Presidents: Taner Demirer and Muhit Ozcan
• 42nd Annual Meeting of the EBMT
– March 2016
– Valencia, Spain– Feria de Valencia– Congress President:
Miguel Ángel Sanz
Upcoming Annual Meetings
#EBMT2014
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1717
• Members will be invited shortly to submit a bid to host the 2018Annual Meeting
• The mail of “Invitation to bid” will be sent to all EBMT Centres at the beginning of May, 2014
• Eligibility criteria, bid specification document and overview of the EBMT Annual Meeting will be then available on the EBMT website
• If interested, please inform EBMT Executive Office in Barcelona
• Deadline for expression of interest is: 10 June 2014
Bids for EBMT 2018
#EBMT2014
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18
Quality
#EBMT2014
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1919
• 57 inspections completed - highest ever!
• 55 inspections reports received
• 57 applications received
• 42 accreditations awarded
• First applications received from Ireland and Hungary
• 51 Inspector Training Course participants – second highest since 2003!
JACIE
#EBMT2014
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20
EBMT 2014 Annual Meeting
#EBMT2014
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2121
2014 Annual Meeting
• Meeting place for scientists, physicians, nurses, statisticians,clinical research technicians and patients
• Biologists and technicians meet for the first time on the occasion of the 2nd Meeting of the Cell Processing Group
• Figures:
– 4,501 delegates
– 21 symposia
– 9 educational sessions
– 17 workshops
– 11 working party sessions
– 60 sponsored booths
#EBMT2014
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22
Acknowledgements
#EBMT2014
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2323
Acknowledgements
#EBMT2014
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24
Outgoing Working Party Chairs and
Nurses Group President
#EBMT2014
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2525
Acknowledgements –
Outgoing Working Party Chairs
Christina PetersPaediatric Diseases Working
Party
#EBMT2014
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2626
Acknowledgements –
Outgoing Working Party Chairs
Judith MarshSevere Aplastic Anaemia
Working Party
#EBMT2014
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2727
Acknowledgements –
Outgoing Nurses Group President
#EBMT2014
Elisabeth WalhultNurses Group President
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2828
Acknowledgements –
Outgoing Working Party Chairs
#EBMT2014
Andrea VelardiImmunobiology Working Party
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2929
Acknowledgements –
Outgoing Working Party Chairs
Mohamad MohtyAcute Leukaemia Working Party
#EBMT2014
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3030
Acknowledgements – EBMT Staff
#EBMT2014
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www.ebmt.org#EBMT2014
Treasurer’s Report
Fred Falkenburg
Milan, Italy
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3232
SOURCE of INCOME
in 1,000€
Membership 408 13% 565 19%
Sponsoring 430 13% 470 16%
Annual Meeting 923 29% 983 34%
Others 109 3% 58 2%
Non-earmarked Income 1.870 58% 2.076 71%
Studies & CT & Education 1.039 32% 371 13%
Accreditation (JACIE) 314 10% 165 6%
Other Grants 10 0% 293 10%
Earmarked Income 1.363 42% 830 29%
TOTAL Income 3.232 100% 2.906 100%
2012 2013
Income
#EBMT2014
The reduced income for JACIE is not an actual decrease, but due to a one time change in accounting system
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3333
HOW EBMT SPEND THE MONEY
in 1,000€
Retrospectives Studies 1.064 32% 771 25%
Prospective Studies 566 17% 383 12%
Educational Activities 188 6% 236 8%
EBMT Registry 486 15% 497 16%
Accreditation Process (JACIE) 274 8% 301 10%
Nurses Activities 85 3% 51 2%
Committees Activities 3 0% 10 0%
Registry Upgrade 54 2% 251 8%
Total Mission 2.721 81% 2.500 81%
Management & Administration 629 19% 570 19%
TOTAL Cost 3.350 100% 3.070 100%
2012 2013
Expenses
#EBMT2014
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3434
Income
Summary Final '12 Final'13
Dec Dec
01 Structural 1.883.415 2.063.870
02 Studies & Education & Acreditation 1.276.749 526.235
03 Others 72.082 315.923 3.232.246 2.906.028
Expenses
Summary Final '12 Final'13
Dec Dec
01 WP 160.054 176.000
02 Divisions & Committees 100.557 61.476
03 Units 3.028.538 2.528.165
04 Others 61.389 304.480 Total 3.350.538 3.070.121
20132012
Result
#EBMT2014
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3535
Net Result
Final '12 Final'13
Dec Dec
Income 3.232.246 2.906.028
Costs 3.350.538 3.070.120
Result -118.291 -164.092
Result
#EBMT2014
The deficit is in part due to the change in accounting system. The operational deficit in 2013 is approximately 50.000€
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3636
BALANCE 2013
(financial situation at the of the year)
in 1,000€ % %
Cash & equivalents 4.108 79% 2.263 50%
Other current assets 1.082 21% 2.275 50%
Total Net Assets 5.190 100% 4.538 100%
Earmarked funds 350 7% 287 6%
Non-earmarked funds 2.293 44% 2.247 50%
Other Reserves 135 3% 79 2%
Total Reserves 2.778 54% 2.613 58%
Current Liabilities 2.412 46% 1.925 42%
Total Liabilities and Reserves 5.190 100% 4.538 100%
2012 2013
Balance
#EBMT2014
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3737
2013
(financial situation at the of the year)
in 1000€ in 1000€
Earmarked funds 350 287
Non-earmarked funds 2.293 2.247
Other Reserves 135 79
Total Reserves 2.778 2.613
2012 2013
Reserves
#EBMT2014
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38
Management Letter 2013
#EBMT2014
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3939
Management Letter 2013
#EBMT2014
• EBMT is not required by law to have a third party audit the financial statements.
• EBMT has started to introduce mechanisms of control, accountability and transparency in order in the future to be fully audited.
• For that reason, EBMT has prepared in cooperation with auditors EY an internal control framework.
• This internal control framework is almost fully completed and implemented in the organization but still some work should be done in 2014 with the objective to further reduce financial risk and gain financial stability and assure that the money is expended according our Mission.
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40
Financial Committee RecommendationsJan Cornelissen & Charles Craddock
#EBMT2014
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4141#EBMT2014
The Financial Committee:
•Approves the financial report 2013.
•Appreciates the major improvements in governance and financial control.
•Supports the investment on a new Staff within the JACIE Structure
•Recommends to solve the VAT issue in 2014.
Financial Committee Recommendations
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4242
• Advices to limit the deficit for 2014 to a maximum of 100.000€and keep the non-earmarked reserves above 2.000.000€
• The Financial Committee expresses concerns on the persistent deficit that EBMT has been facing in the last 2 years (2012 and 2013) and the prevision of a continuing deficit in the budget from 2014.
Financial Committee Recommendations
#EBMT2014
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43
Approval of the General Assembly
#EBMT2014
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4444
• Financial Report 2013
• Re-appointment of Jan Cornelissen and Charles Craddock
as Financial Committee
Approval of the General Assembly
#EBMT2014
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www.ebmt.org#EBMT2014
Secretary’s Report
Anna Sureda
Milan, Italy
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4646
Centres Membership Overview
Global figures
GAM 2014 vs GAM 2013
Number of EBMT
Centres568 570
Of which PROVISIONAL centres 12 21
Of which FULL centres reporting 495 N/A
Of which ASSOCIATE centres 61 N/A
#EBMT2014
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4747
• The 568 EBMT centres are located in 55 different countries
• The top 10 split of centre per countries is the following
Centres Membership Overview
Per country
Country Numbers of centres 2014 Vs 2013
Nº1 Italy 85 91
2 Germany 80 80
3 U.K. 52 52
4 France 51 49
5 Spain 47 48
6 Turkey 35 36
7 Poland 18 18
8 Belgium 18 18
9 The Netherlands 14 14
10 Austria 11 12
#EBMT2014
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4848
• The following 12 Member Centres have been granted provisional
membership and await for your approval.
Centres Membership Overview
New EBMT Members
CIC First Names Last Name Country
124 Roland Schroers Germany
156 Roman Hajek Czech Republic
158 Régis Costello France
164 Magda Alexis France
181 Juan Manuel Herrera Colombia
368 Andrej Vranovský Slovakia
440 Zafer Gülbas Turkey
441 Hani Al-Hashmi Saudi Arabia
442 Belina Pinto-Simoes Brazil
867 Gianluca Gaidano Italy
912 Andrei Colita Romania
944 Mario Ojeda-Uribe France
#EBMT2014
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4949
1. 25 Centres have been desactivated due to outstanding invoices
EBMT Bye-laws §13 - MEMBERSHIP FEE
“Centres and individuals not paying the membership fee for two consecutive years will be
deleted from the membership list and lose all rights and duties of an EBMT
member”.
All Centres with outstanding invoices have been contacted and 25 centres have been desactivated from the EBMT Membership database losing all benefits including the access to the Registry data
2. Some Centres have merged / split and some other have re-activated their
membership.
Centres Membership Overview
Global evolution
#EBMT2014
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The following number of member centres have had
their membership status changed due to data reporting:
• Full to Associate: 17
17 Centres have stopped reporting and have been moved from Full Members to ASSOCIATE
• Associate to Full: 6
6 centres have resumed reporting and have been moved from Associate to FULL
Centres Membership Overview
Centres Membership Status Changes
#EBMT2014
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Individual Membership Overview
Main figures
GAM 2014 Vs GAM 2013
Individual Membership 77 81
Of which PROVISIONAL 9 14
Physicians 40 35
Nurses 28 32
Honorary Members 27 24
#EBMT2014
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1. 14 Individual Patrons have been desactivated due to outstanding invoices
or on their own decision
EBMT Bye-laws §13 - MEMBERSHIP FEE
“Centres and individuals not paying the membership fee for two consecutive years will be
deleted from the membership list and lose all rights and duties of an EBMT
member”.
Individual Patrons Overview
Global evolution
#EBMT2014
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• The following 9 Individuals have been granted provisional
membership and await for your approval.
Individual Membership Overview
New EBMT Patrons
CIC Country First Names Last Name Role - Designation
10114 Japan Ishii Kazuyoshi Physician
10115 United States Mohamed Kharfan-Dabaja Physician
10129 Japan Shosaku Nomura Physician
10134 Netherlands, The Simone van der Linden Nurse
10147 Israel Nataly Kazman Nurse
10167 China Xia Yan Nurse
10229 Mexico Roberto Ovilla Physician
10322 United States Firoozeh Sahebi Physician
10323 Australia Mark Hertzberg Physician
#EBMT2014
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Working Party Chair Election Results
#EBMT2014
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• Andrea Velardi’s term as Working Party Chair has officially ended.
• He will continue as “acting” Working Party Chair until a decision has been made by the Board of Association regarding the future structure of the Working Parties
• We thank him for his commitment and support while a decision is reached
Immunobiology Working Party
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Working Party Chair Election Results
Acute Leukaemia Working Party
Total Votes 197
Arnon Nagler 117 (59%)
Sebastian Giebel 73 (37%)
No Vote 7 (4%)
#EBMT2014
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Working Party Chair Election Results
#EBMT2014
Paediatric Diseases Working Party
Total Votes 197
Jean Hughes Dalle 66 (33%)
Peter Bader 104 (53%)
No Vote 27 (14%)
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Working Party Chair Election Results
#EBMT2014
Severe Aplastic Anaemia Working Party
Total Votes 197
Carlo Dufour 162 (82%)
No Vote 35 (18%)