Technical features of Ploom Tech,JTI’s novel tobacco vapor device
Ian Jones, PhDVice President, Reduced-Risk ProductsJT International
Inhalable tobacco products in
which the tobacco is not
combusted during intended
use
Tobacco Vapor Products (TVPs)
Non-combusted tobacco
products for inhalation
(NCTPIs)
What is Tobacco Vapor ?
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Tobacco Vapor Category:existing technologies
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Direct heatingIndirect heating
(Air)
Ambient
(no heating)
Indirect heating
(Liquid)
Heats or Burns or Combusts?..
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Indirect heating Direct & indirect heating Combustion
Co
0 100 200 400 500 600 700 800300
Heated sticks
CigarettesCharcoal heated
Heated pods
Hybrid products
Human bodytemperature
Domestic oven Pizza oven The middle of a fireplace
Ploom Tech hybrid device
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TECH-CAP
• Specially blended
granulated tobacco
CARTRIDGE
• Contains non-nicotine containing liquid to create vapor
BATTERYTOBACCO VAPOR
• No smoke, no smoke smell, no ash
How Ploom Tech works
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Aerosol picks up tobacco
flavour and nicotine from
tobacco particles
Aerosol with tobacco
flavour/nicotine
from tobacco
CARTRIDGETECH-CAP
HeaterPlain Aerosol Liquid
°C
100
200
400
500
600
700
800
300
0
30°C
Scientific data: Vapor chemistry
Approximately 99% reduction in levels of measured
constituents compared to cigarette smoke
Source:Chemical and in vitro toxicological analysis of a vapor from a novel tobacco vapor device and capsuleTakahashi, Y; Kanemaru, Y; Fukushima ,T; Eguchi K and Miller-Holt, JPresented at EuroTox 2016
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Scientific data: In vitro toxicology
Micronucleus assay
AMES assay Neutral red assay
◆:3R4F ■:NTV
Source:Chemical and in vitro toxicological analysis of a vapor from a novel tobacco vapor device and capsuleTakahashi, Y; Kanemaru, Y; Fukushima ,T; Eguchi K and Miller-Holt, JPresented at EuroTox 2016
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Scientific data:In vitro cellular responses (human bronchial epithelial cells)
Strong potential to be a reduced-risk product
Source:Comparative effects of cigarette smoke and novel tobacco product vapor on in vitro cellular responses in human bronchial epithelial cellsMunakata, S; Ishimori, K; Takanami, Y; Ishikawa, S; Ito, SPresented at Society of Toxicology Annual Meeting 2017
Evidence of correlation between tobacco temperature and biological activity
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Lower cell toxicity than directly-heated tobacco
vapor (HnB product) or cigarette smoke
C
o
0100200400500600700800 300
Cigarette
Competitive directly
heated product in Japan
Evidence of correlation between tobacco temperature and vapor chemistry
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C
o
0100200400500600700800 300
90%
93%
95%
99%Stated reductions in measured harmful and potentially harmful vapor constituents (HPHCs) compared to cigarette smoke
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Summary
Ploom Tech:
• A tobacco vapor product
• Hybrid technology
• Indirectly heats tobacco to 30 °C
• No burning of tobacco, no smoke, smoke smell or ash
• 99% reduction in measured HPHCs in vapor compared to smoke
• Significantly reduced in vitro biological responses compared to
smoke
Has strong potential as a reduced-risk product
Thank you!
Any questions?
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