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Download - T cell VEGF Other Surface atezolizumab AntigenRVEGF- R RTK-R · DNA-PK M3814 PARP olaparib talazoparib veliparib HDAC belinostat entinostat ... TAK-243 E-selectin uproleselan Hedgehog

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Page 1: T cell VEGF Other Surface atezolizumab AntigenRVEGF- R RTK-R · DNA-PK M3814 PARP olaparib talazoparib veliparib HDAC belinostat entinostat ... TAK-243 E-selectin uproleselan Hedgehog

RasRaf

MEK Btk

SrcAblBcr

PI3K

Akt

BAD

BCL2

XIAP

mTOR

Apoptosis

RNRp53MDM2

Survival / Proliferation

AngiogenesisMigration / InvasionMitosisImmunomodulation

DNA Replicationor Repair

Protein expressionor metabolism

VEGF-R

VEGFOther SurfaceAntigen-R

T cell

RNRWEE1

PD1nivolumabpembrolizumab

PD-L1durvalumabatezolizumab

IMiDslenalidomidepomalidomide

CTLA4ipilimumabtremelimumab

BiTEblinatumomab

CCR4mogamulizumab

CD27varlilumab

IDO-1epacadostat

Dendritic Cell RCDX-1401

IL-12 Cell RIL-12

IL-15 Cell RrIL-15

Oncolytictalimogene laherparepvec

BERmethoxyamine

ATRM6620AZD6738

DNA-PKM3814

PARPolaparibtalazoparibveliparib

HDACbelinostatentinostatromidepsin

DNA polymeraseIPdR

EZH2tazemetostat

triapinegemcitabine

DNA methylationazacitidineguadecitabine

HER2trastuzumab

IGF-1Rganitumab

CD30brentuximab

GPNMBglembatumumab

Mesothelinanetumab ravtansine

radiopharmaceuticalradium-223thorium-227

Proteosomebortezomibixazomib

adavosertib KRT232 triapinegemcitabine

Glutaminase-1telaglenastat

HSP-90onalespib

GD2dinutuximab

HGF/SFrilotumumab

FGFRrogaratinib

UAETAK-243

E-selectinuproleselan

Hedgehogvismodegib

Estrogen Rendoxifen

VEGF-Rbevacizumabziv-aflibercept

CD-105TRC-105

WEE1adavosertib

Aurora kinase Aalisertib

Microtubuleseribulin

navitoclaxvenetoclax

temsirolimus

RTK-R

cMETAMG-337savolitinibcabozantinibtivantinib

PDGFRpazopanibcedirinibsunitinib

dabrafenibsorafenib

dasatinib

copanlisibAZD-8186

ibrutinibselumetinibtrametinib

TORCsapanisertib

cedirinibsunitinibsorafenibcabozantinib

birinapant

BET proteinsi-BET-762

ICOSMEDI-570

Nedd8 AEpevonedistat

osimertinibrociletinib

DOT1Lpinometostat

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