Download - Supplementary S1

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Page 1: Supplementary S1

Supplementary S1

A

B

C

PS

D-9

5 (

r.u

)P

SD

-95

(r.

u)

PS

D-9

5 (

r.u

)

PSD-95

tubulin

tubulin

PSD-95

tubulin

A oligomers

Nicotine

-Btx

---

+--

++-

+++

-+-

--+

- -

+

- +-

A oligomers

Nicotine---

+--

++-

+++

+-Wortmannin

BSD

+A oligomers

Nicotine---

-+-

++-

+-

++

DHE

-

--+

1.5

1.0

0.5

0

2.0

1.0

0

1.0

0.5

0

PSD-95

Page 2: Supplementary S1

Supplementary S2

BA

NicotineWild typeNicotine

Wild type

ControlWild type

ControlWild type

Page 3: Supplementary S1

Afibrils A+Nicotine (100 M; 24h)

b

B

Supplementary S3

A a

Page 4: Supplementary S1

Supplementary S4

A

C

B

*

*


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