Download - Stats 11, Winter 2004
![Page 1: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/1.jpg)
Stats 11, Winter 2004
Experimental Design
Jan 9, 2004
![Page 2: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/2.jpg)
London Cholera Outbreak, 1854
• Cholera kills quickly
• Primary symptom is severe diarrhea
• Modern treatment involves an IV to provide hydration
• Competing Theories for transmission: air vs water (germs). Air was the predominant view.
![Page 3: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/3.jpg)
Golden Square, Sept 1854
• Unusually intense, deadly outbreak
• 500 deaths in just a few days
• Local panic made neighbors flee
• John Snow, a physician, believed cholera spread through polluted water supplies
![Page 4: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/4.jpg)
QuickTime™ and aTIFF (Uncompressed) decompressorare needed to see this picture.
![Page 5: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/5.jpg)
![Page 6: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/6.jpg)
Is this definitive "proof"?
![Page 7: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/7.jpg)
Same picture, but with daily deaths
![Page 8: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/8.jpg)
Aside: quarterly aggregates
![Page 9: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/9.jpg)
Fiscal Year aggregates
![Page 10: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/10.jpg)
Calendar Year aggregate
![Page 11: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/11.jpg)
Water compnies
QuickTime™ and aTIFF (Uncompressed) decompressorare needed to see this picture.
![Page 12: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/12.jpg)
This area was fed by two water companies
![Page 13: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/13.jpg)
Deathrate less where clean water
QuickTime™ and aTIFF (Uncompressed) decompressorare needed to see this picture.
![Page 14: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/14.jpg)
QuickTime™ and aTIFF (Uncompressed) decompressorare needed to see this picture.
![Page 15: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/15.jpg)
QuickTime™ and aTIFF (Uncompressed) decompressorare needed to see this picture.
![Page 16: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/16.jpg)
Current medical mystery
• Sudan's Luckless Children, Locked in Land of Nod, NY Times, Sept 22, 2003
• Mysterious ailment among some children of Sudan
• Nod, don't grow fully, die in late teens• Theories: fly bite, poison,
contaminated food
![Page 17: Stats 11, Winter 2004](https://reader030.vdocuments.us/reader030/viewer/2022033023/56813fda550346895daac0f9/html5/thumbnails/17.jpg)
References found on
• http://www.ph.ucla.edu/epi/snow.html