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Safe harbour statement
This presentation may contain forward-looking statements. Various factors could
cause actual results to differ materially from those projected in forward-looking
statements, including comments predicting the timing of financings, strategic
partnering, regulatory actions, or the capabilities of the platform. Although the
Company believes that the forward-looking statements contained herein are
reasonable, it can give no assurance that the Company‟s expectations are
correct. All forward-looking statements are expressly qualified in their entirety by
this Cautionary Statement. This presentation should not be considered an
official disclosure document of the Company.
This document is for information purposes only and is not intended to be used to
solicit the sale of securities.
SQI Diagnostics™ Inc. PRIVATE and CONFIDENTIAL – NOT FOR
DISTRIBUTION without the express written consent of SQI Diagnostics Inc.
All in One Drop 3
SQI
Diagnostics
Multiplexing,
Miniaturization and
Automation.
Analyze multiple biomarkers,
Deliver accurate patient
results in less time,
Reduce labor, and
Increase profits …
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SQiDworks™ – the first fully-automated
multiplexing workstation for diagnostic
microarrays.
IgXPLEX™
Patented Microarray Assay
providing 3 strategic customers benefits
Confidence, Profit and Growth
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Value creation
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Microarray concept
Multipexed array demo
Automated array
scanning
A-G-M calibration
Fully automated
system
Health Cda approval
Surface optimization
Printing optimization
RA panel validation
FDA clearance
U.S. market launch
Complete AI panels
1st ID panels filed
SQiDman launch
2005 2006 2007 2008 2009 2010 2011
Scale up capital
Technology investment
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Current multiple biomarker testing is labour intensive
1 test
1 unit of reagents
1 unit of labour
1 result
6 tests
6 units of reagents
6 units of labour
6 results
SINGLE biomarker testing
MULTIPLEbiomarker testing
No economies of scale
for multiple testing!
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Study of 324 clinical laboratories by Chi Solutions in 2008
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57.9%Labor &
Benefits
20.9%Supplies
0.6% Lease/Rental
1.5% Repair
2.4% Depreciation
6.0% Other
8.9% Send Outs
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Evolution with Purpose: 4th Generation
Discovery Antigen / Antibody
ELISA
Multiple samples on single plate
Lab Automation
Multiple samples in single run
Bead Based Multiplexing
Multiple analytes/samples
IgXplex 2010
Multiple analytes
Isotypes
Samples
In single run
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SQI Diagnostics‟ IgXplex:
The Next Generation
Immunoassay
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Complete automation of all assay steps
Integrates with standard lab automation systems
Throughput: 222 patients / run
~700 patient results / hour .
Productivity!
Load & Go
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Productivity!
Load & Go
Fully Automated Platform Comparison: Isotyping 6 Analytes
SQI- IgXplex Auto-Luminex Auto -ELISA
Reagent Kits: 1 Reagent Kits: 6 Reagent Kits: 18
Consumable Sets: 1 Consumable Sets: 6 Consumable Sets: 18
Hands On Time: 30 Minutes Hands On Time: 5 Hours Hands On Time: 9 Hours
Steps Needed: 5 Steps Needed: 126 Steps Needed: 90
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IGXPLEX™
• Multiplexing at 2 levels – antigen
& antibody class (IgX PLEX™)
• Industry-standard 96 well format
• 74 patients per consumable
12plex‟d = 888 biomarker results
per consumable
• Up to 12 biomarkers tested
quantitatively and 24 screening
• 23 within well, 72 within plate
multiple tests / multiple patients
results with < one unit of labour
1 well
1 patient
Multiple Results
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SQI Diagnostics value proposition: dramatic economies of scale
Traditional manual biomarker testing
74 patients | 9 biomarker
requiring 18 “plates”
SQI Diagnostics biomarker testing
74 patients | 9 biomarkers
requiring 1 “plate”
~ 3 seconds
per biomarkerTechnician „hands-on‟ time
~ 4 minutes
per biomarker Technician „hands-on‟ time
Automated micro array technology powering a technology shift…
80 X
Reduction
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Profit increases by up to $40 per patient in 9-
plex panel
36 minutes / patient
Beta2 CL PS
Patient Well Costs $12.00 $12.00 $14.25
Reagent Cost 1.50 1.50 1.50
Tech Labour 12.00 12.00 12.00
Lab Overhead 1.20 1.20 1.43
Total: $82.58
Costs Beta 2 Cardio-L PS
Patient Well Cost $38.25
0.23
0.25
3.82
Reagent Cost
Tech Labour
Lab Overhead
Total: $42.55Total: $82.58
0.3 minutes / patient
18 microtiter plates required
Current Method IgX-Plex
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Sales Funnel
“Current” Target Market
Labs in USA14,000
300
60
6–10
Current Focus Accounts
Target Installs for
2010
Meetings Completed/Scheduled20
1 Completed Validation (to date)
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Candidate Panels Insight Proof of
Concept
Assay
Develop
Automation Verification Multisite
Validation
Regulatory
Submission
Six-Month Internal Development
Timeframe
Infliximab (RUO)-3x
Vasculitis-4x RA v2Auto Hep
Renal
Food
Intolerance
Celiac-4x
Thyroid-3x
Lupus-12x
BOTX-3x
IBD-8x
Current Product Pipeline
Customer
Delivery
APS-9x
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Goals for 2010
Three assays submitted to FDA
FDA Clearance for at least one
New Product
Two OEM products delivered
Multiple Health Canada
Approvals
Six Customer installation Sites
Customer Revenue20
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Company overview
Headquarters: Toronto, Ontario
Founded: 1999
Symbol: TSX.V SQD
Financial data :27,193,000 shares issued and outstanding
32,279,000 shares on a fully diluted basis
$26.5 million raised since 2004
$8.543 million current assets as at December 31, 2009
Cash in place through 2011
Cash burn rate of ~$625,000 per month