School of Electrical, Electronic and Mechanical Engineering
Nano-particles and nano-structured surfaces in biomedical engineering.Dr. Kenneth Stanton
SEEME: Biomedical engineering
• Development and/or design of materials, devices and manufacturing routes for implantable biomedical components including:– Orthopaedic joints– Stents– Dentistry– Etc
• Study of mechanical properties of biomaterials and biomedical devices.
• Biomechanics of bone, joints, soft-tissue etc.
• Bio-tribology and wear.
Nano-particles evolved during wear of orthopaedic joints
• With each step there are 5x105 particles released
• Particles are found disseminated to organs around the body
• There is little understanding about the long-term biological effects of nanoparticles of the relevant materials– Effects of morphology– Fresh surfaces– Metal nanoparticle stability
Synthesis of nano-crystalline bioceramics and glass-ceramics
• HA, -TCP:– Bi-phasic calcium phosphates
• Controlled resorbability in-vivo
– Preparation of nano-structured surfaces from bioceramics using EPD from wet-precipitation.
• Apatitic glass-ceramics
Preparation of nano-structured metal-oxide surfaces using RF-magnetron sputteringEffect of deposition pressure on microstructure of TiOx coating
4 x 10-3 mbar
1 x 10-3 mbar
Courtesy of Denis Dowling