Download - Rob O'Connor, Irish Cancer Society Research
Robert O’Connor, Ph.D. Head of Research & Head of Communications, Irish Cancer Society
“We can’t treat ourselves out of the emerging cancer and healthcare crisis”-
www.cancer.ie/research@drrobertoconnor /@irishcancersoc1
The Irish Cancer Challenge -Currently
• > 40,000 cancers newly diagnosed 2016– >20,000 invasive cancers
• ~9,000 die annually
• Communicating this?– 40,000/365 = 110 per day 1/~13 mins– a death every hour of the week.
• In reality – working week– A diagnosis every 3 mins, – A life changing diagnosis every 6 mins of working week
• 1/3 will have cancer diagnosis in lifetime
• numbers Doubling in 25 years!!
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The Irish Cancer Challenge –future
• NCRI cancer projections from 2010 to 2040
http://www.ncri.ie/sites/ncri/files/pubs/Cancer%20projections%20for%20Ireland%202015%20-%202040.pdf4
Why is this happening?
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Older = more cancer
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Age group
Cancer Incidence by age in Ireland 2004-2011
Female
Male
Strong mutationUVChance
Previous & currentenvironmentMutational “load”Summary geneticsChance
http://www.ncri.ie/data/incidence-statistics (all invasive cancers)6
Our population is aging = more disease
Health in Ireland – Key trends 2015, Dept of Healthhttp://health.gov.ie/wp-content/uploads/2015/12/Health_in_Ireland_KeyTrends2015.pdf8
So the numbers of people getting cancer are increasing
• Age
• Lifestyle
• Awareness & diagnosis
• More public openness about cancer
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The cost of treatment
• 2009 cancer cost Ireland €1.5billion or 0.9% of GDP
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Cancer drug costs exploding
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Numbers of new drugs increasing
15 for cancer indications
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Summary
• Numbers getting cancer will continue to rise
• Treatments can be effective but
• Costs per patient are shooting up
⇒On an ECONOMIC BASIS
• WE WILL NOT TREAT OURSELVES OUT of this “EPIDEMIC” of CANCER
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Research is saving lives– right here in Ireland
54% of adults cured (alive 10 years after diagnosis)Children - >90% of children leukemias cured
~70% of them involved in research by being on a trial
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The reality of that current cancer “cure”
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A cure – at what cost….
• Disability
• Fatigue
• Sexual issues
• Mental health
• Chronic pain
• Medical issues
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The Real Cost of Cancer in Ireland
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Cancer survivors
• >1/4 are disabled in some way following their treatment
• But they are LIVING LONGER too• Economics
– The personal costs are significant– Treatment and after treatment mount up–Ability to make economic contribution
evaporates• THE COST OF SUSTAINING SURVIVORS IS ALSO
MOUNTING
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What do we do?
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RESEARCHWE’RE
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Research & ACTING ON research findings is the key
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Action research
– Applying same investment and rigour as employed in medicine research (clinical trials) to rest of the cancer “problem”
• Test hypotheses about improving healthcare
– Prevention
– Early detection
– Treatment Efficacy
– Post treatment and End of life care
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Prevention
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Smoking prevention
• Smoking kills ~5,500 Irish people each year
• Annual Irish Health care costs alone > €500m (2009)
• Typical cessation success rates
– Drugs/cold turkey etc. ~5%
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We can quit
• Evidence-based 12 week supported programme in women from poorer communities
• 46% Quit rate
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Early detection
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Early bowel cancer detection
• Bowel cancer kills ~1000 Irish people annually
• But only 40% of women and 36% of men take free FIT test for bowel cancer
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UK early detection figuresFrom
Early Detection – saves lives & money
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Post treatment exercise –46% lower mortality!
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MedEx
• Exercise improves outcome after serious disease
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Summary
• Cancer numbers are inexorably climbing
• Much we can do to reduce disease & increase quality longevity
• Modern, personalised cancer treatment is becoming economically unsustainable– WE WILL NO TREAT OURSELVES OUT OF THIS
• No single solution
• Need to attack problem at each point of intervention
• Research is our only tool to guide evolution of a sustainable “wealthy” health future
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