Download - Research activities 2015
![Page 1: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/1.jpg)
Research Activities 2015
Assist. Prof. Eric Chan Wei Chiang
![Page 2: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/2.jpg)
Main research areas
1. Effects of heat treatment on bioactivity of food
2. Isolation of bioactive natural products
3. Production of carboxymethyl hydrogels
![Page 3: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/3.jpg)
Effects of heat treatment
Thermal treatments used in food preparation and processing is widely considered to degrade biomolecules and reduce any bioactive properties
However, our recent showed thermal and non-thermal drying treatments enhanced the bioactivity of certain herbs
The herbs studied were Etlingera elatior (Torch ginger), Morus alba (Mulberry) and Thunbergia laurifolia (Blue trumpet vine).
![Page 4: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/4.jpg)
Antioxidant assays and drying treatments
Assessment of Antioxidant Properties
Total phenolic content (TPC)
DPPH Radical Scavenging (AEAC)
Ferric reducing power (FRP)
Drying treatments
Microwave drying Oven drying Sun-drying Air drying Freeze drying
![Page 5: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/5.jpg)
Microwave-drying enhanced the AOP of T. laurifolia leaves with 34% increase in total phenolic content and 67% increase in radical scavenging ability
Leaves of M. alba responded positively to Microwave-drying, Oven-drying and Freeze-drying.
Freeze-drying enhanced the AOP of leaves of E. elatior
Effects of heat treatment
![Page 6: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/6.jpg)
Overlay of chromatograms showed greater amounts of minor compounds in freeze-dried than fresh leaves.
The HPLC chromatogram of freeze-dried leaves of E. elatior showed greater amounts of minor compounds than fresh leaves
![Page 7: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/7.jpg)
Undergraduate students
Suit Ying
Phui Yan
Michelle
![Page 8: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/8.jpg)
Quorum quenching by methyl gallate isolated from cashew leaves Methanolic extract of cashew leaves was assessed
for quorum sensing (QS) inhibition using the disc-diffusion assay with Chromobacterium violaceum
The extract exhibited strong anti-QS activity
From the extract, methyl gallate was isolated by column chromatography and identified by NMR and MS spectroscopy, and quantified using reversed-phase HPLC.
![Page 9: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/9.jpg)
HPLC quantfication
Content of methyl gallate was found to be 1830 ± 180 μg/g of leaves
![Page 10: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/10.jpg)
Postgraduate alumni
Yuen Ping produced 9 publications upon completion of her MSc.
![Page 11: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/11.jpg)
Further research with UM-HIR
Thiba a PhD candidate under Dr Chan Kok Gan would be testing herbs for quorum quenching on different E. coli strains which produce long-chain and short-chain AHL signalling molecules.
![Page 12: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/12.jpg)
FRGS:Root Targeted Delivery Vehicle for fertilizers using cellulose fromagricultural waste Malaysian agriculture is very
productive and generates large amounts of wastes annually
Plant biomass from agricultural waste is a rich underutilised source of cellulose that can be used to manufacture carboxymethyl cellulose
Waste from Malaysian agriculture can be fully utilised to create a root targeted, slow-release fertilizer system
![Page 13: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/13.jpg)
Root targeted delivery systems
Hydrogel beads Commercial RTDV Estate wastewater
![Page 14: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/14.jpg)
Current MSc students
Pei Xin and Caroline
![Page 15: Research activities 2015](https://reader030.vdocuments.us/reader030/viewer/2022032503/55c0470bbb61ebe0398b45c0/html5/thumbnails/15.jpg)
Thank you