Download - Renal pathology
Renal pathologyRenal pathology
Nephrotic SyndromeNephrotic Syndrome
Primary glomerular diseasesPrimary glomerular diseases
1.1. Minimal change disease / Lipoid nephrosisMinimal change disease / Lipoid nephrosis
2.2. Focal Segmental GlomerulosclerosisFocal Segmental Glomerulosclerosis
3.3. Membranous Nephropathy /MGNMembranous Nephropathy /MGN
4.4. MPGNMPGN
Minimal change disease / Lipoid Minimal change disease / Lipoid nephrosisnephrosis
Normal in light microscopyNormal in light microscopy Electron Electron diffuse effacement of podocyte diffuse effacement of podocyte
foot processesfoot processes
Membranous GlomerulonephritisMembranous Glomerulonephritis
MPGNMPGN
Nephritic SyndromeNephritic Syndrome
1.1. Acute Post infectious GNAcute Post infectious GN
2.2. IgA NephropathyIgA Nephropathy
3.3. Heriditary nephritisHeriditary nephritis
Post streptococcal GNPost streptococcal GN
Ig A NephropathyIg A Nephropathy
Usually affects children and young adultsUsually affects children and young adults 1 or 2 days after a non specific upper 1 or 2 days after a non specific upper
respiratory tract infectionrespiratory tract infection
Deposition of Ig A in the mesangium is the Deposition of Ig A in the mesangium is the hallmark of the diseasehallmark of the disease
Histo Histo
Variable Variable FPFP MPMP Crescentic GnCrescentic Gn
RPGN/ CrescenticRPGN/ Crescentic
Clinical syndromeClinical syndrome Not a specific etiological form of GNNot a specific etiological form of GN
Types Types
Type 1 Type 1 Anti GBM antibodyAnti GBM antibody Good Good Pasture SyndromePasture Syndrome
Type 2 Type 2 Immune complex Immune complex Post Post infectious , SLE , IgA nephropathyinfectious , SLE , IgA nephropathy
Type 3 Type 3 Pauci immune – ANCA Pauci immune – ANCA associated-----Wegener’s Granulomatosis , associated-----Wegener’s Granulomatosis , Microscopic angitisMicroscopic angitis
Type 1 Type 1
Type 2 Type 2
Renal Cell CarcinomaRenal Cell Carcinoma
1.1. Clear cell carcinomaClear cell carcinoma
2.2. Papillary carcinomaPapillary carcinoma
3.3. Chromophobe carcinomaChromophobe carcinoma
4.4. Collecting Duct carcinomaCollecting Duct carcinoma