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Reconstruction of Blood Vessel Trees from Visible Human
DataZhenrong Qian and Linda ShapiroComputer Science & Engineering
DepartmentUniversity of Washington
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Introduction
• Goal– to reconstruct the blood vessels of the lungs
from Visible Human Data• Computer vision
– semi-automation– low-level image processing– model construction
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Visible Human Data: Slice through the Lung
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Problems Encountered• Data source
– black spots that are not blood vessels– variations of lighting
• Characteristics of blood vessels– similar color surrounds– lack of knowledge – close location– shape variety– continuous change not expected – dense data
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Finding the contours of a vessel being tracked (1)
Previous contour Current slice
EM Segmentation False color for the segmentation
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Finding the contours of a vessel being tracked (2)
• The results after selecting regions of similar color to the tracked region
Segmentation result Selected regions
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Finding the contours of a vessel being tracked (3)
• The results after selecting the region that overlaps most with the previous contour
Region that overlaps most
Selected regions
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Find the contours of a vessel being tracked (4)
• The results after morphology to close holes and remove noise
Selected region After noise removal
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Find the contours of a vessel being tracked (5)
• The contour is determined through a fast-marching level-set approach
Previous contour Current contour
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How branching is handled• One contour divides into two
• Two contours merge into one
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The use of resampling when the axis is not vertical
• Track the axis through the center points of found contours
• Fit a spline curve
• Resample the data perpendicular to the spline curve
• Use the resampled contours for model creation
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27Center points of found contours
Detect the axis
Spline-fitted axis
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Resample the data perpendicular to the spline curve
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Overall Procedure for finding Vessel Trees
• The user selects a starting point
• The program automatically tracks the selected vessel and any branches it finds
• The program creates a generalized cylinder representation of the vessel tree
• The user may select more starting points
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Some Initial Results
Artery tree from single seed Vein tree from single seed
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Typical Cross Section
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Results : blood vessels in right lung from previous section