Download - Pharmacology MCQ
-
Question 1
1.
Which is a component of cocktail therapy vs.
AIDS?
Answer
Amantadine
Zidovudine
Acyclovir
Vancomycin
Ribavirin (virozole)
1 points
Question 2
1.
Atropine can induce
Answer
"tachycardia, dry mouth"
"bradycardia, miosis"
"tachycardia, salivation"
"tachycardia, miosis"
-
"bradycardia, salivation"
1 points
Question 3
1.
Lugols Solution (Iodine) can be used to
treat
Answer
hyperthyroidism
hypogonadism
allergy
diabetes
hypothyroidism
1 points
Question 4
1.
After long-term use of Glucocorticoids,
rebound phenomenon will occur if the dosage
is reduced rapidly, it is because
Answer
-
adrenal suppression
iatrogenic Cushing syndrome
glucocorticoid dependence
increased ACTH secretion
decreased pituitary function
1 points
Question 5
1.
Which drug is addictive antitussive
Answer
Ammonium chloride
Dextromethorphan
Benzonatate
Codeine
Pentoxyverine
1 points
Question 6
1.
-
Pharmacological mechanism of Cardiac
Glycosides is
Answer
Inhibition of cAMP
Inhibition of H+-K+-ATPase
Inhibition of Na+-K+-ATPase
Inhibition of P-450
Inhibition of Phosphodiesterase
1 points
Question 7
1.
Which drug can be used for abortion
Answer
Prostaglandins
Ritodrine
Ergometrine
Oxytocin
Indomethacin
1 points
-
Question 8
1.
Which of the following drugs can inhibit the
DNA-dependent RNA polymerase?
Answer
Penicillin G
Rifampin
Streptomycin
Chloramphenicol
Cefoperazone
1 points
Question 9
1.
The effect of Cholestyramine on blood lipid
is
Answer
Reduce TC and LDL-C
Reduce TG and HDL
Reduce CE and FFA
-
Reduce TC and VLDL
Reduce TC and CM
1 points
Question 10
1.
Which one is NOT a main adverse effect of
Streptomycin?
Answer
Nephrotoxocity
Vestibular toxicity
Hepatotoxicity
Neuromuscular Paralysis
Cochlear toxicity
1 points
Question 11
1.
The most active aminoglycoside against
Mycobacterium tuberculosis is
Answer
-
Kanamycin
Neomycin
Amikacin
Streptomycin
Tobramycin
1 points
Question 12
1.
The H2 receptor antagonists are mainly used
to
Answer
hypertension
asthma
diabetes
intestinal spama
peptic ulcer
1 points
Question 13
1.
-
Which pathogen is susceptible to
Azithromycin?
Answer
Plasmodium
G coccus
G bacillus
Rickettsia
Anaerobic bacteria
1 points
Question 14
1.
The most important mechanism of
Cephalosporins acquired resistance is
Answer
the change of metabolism pathway
produce the -lactamases
reduction of cell membranes perrmeability
active efflux system
modification of target sites
-
1 points
Question 15
1.
Which drug has the mucoprotective effect for
ulcer treatment
Answer
Ranitidine
Magnesium trisilicate
Omeprazole
Atropine
Sucralfate
1 points
Question 16
1.
The correct time for alternate-day
adiministration of Glucocorticoids is
Answer
4:00 AM
8:00AM
-
8:00 PM
4:00 PM
12:00 AM
1 points
Question 17
1.
The common effect of Nitroglycerin and
Propranolol in angina treatment is
Answer
decrease heart rate
decrease peripheral resistance
decrease myocardiac contraction
decrease myocardiac oxygen consumption
decrease ventricular volume
1 points
Question 18
1.
Which of the following effect is the adverse
drug effect of Heparin
-
Answer
Peptic ulcer
Pypertension
Asthma
Bleeding
Abnormalities of renal function
1 points
Question 19
1.
Which of the following antibacterial agents
can inhibit folic acid metabolism?
Answer
Quinolones
Aminoglycosides
Clindamycin
Cephalosporins
Sulfinamides
1 points
Question 20
-
1.
Which one is NOT the clinical use of Oxytocin
Answer
induction of labor
induction of abortion
augmentation of labor
promote milk ejection
postpartum hemorrhage
1 points
Question 21
1.
Which one is rapidly effective for acute
asthmatic attack
Answer
oral administration of Aminophylline
Cromoglicate sodium
Aalbutamol inhalation
Beclomethasone
Ketotifen
-
1 points
Question 22
1.
Valsartan is
Answer
Ca2+ channel blocker
-blockers
Cardiac Glycosides
Angiotensin II receptor blockers (ARBs)
Angiotensin-Converting Enzyme Inhibitor(ACEI)
1 points
Question 23
1.
For the roundwarm and pinwarm infection,
preferred drug is
Answer
Praziquantel
Levamizole
Mebendazole
-
Piperazine
Pyrantel
1 points
Question 24
1.
Penicillin G is the 1st choice against
Answer
Gbacillus
Hemolytic Streptococcus
Mycobacterium tuberculosis
Enterococci
Shigellosis
1 points
Question 25
1.
The mechanism action of Heparin is
Answer
block the Ca++ action
active the ATIII
-
counteract to the VitK
antagonize the VitK effect
"inhibit the synthesis of thrombin II , IX, X"
1 points
Question 26
1.
A 35-year-old female complains of itching in
the vulval area. Hangingdrop examination of
the urine reveals trichomonads. What is the
preferred treatment for trichomoniasis?
Answer
Emetine
Metronidazole
Pyrimetamine
Pentamidine
Doxycycline
1 points
Question 27
1.
-
The mechanism of Glucocorticoids for asthma
treatment is
Answer
stimulate respiratory centre
activate adenyl cyclase
dilate airway smooth muscles
anti-inflammation and anti-allergy
block M-receptor
1 points
Question 28
1.
Adverse Effects of Angiotensin Converting
Enzyme (ACE) Inhibitors are NOT including
Answer
Ventricular bradycardia
Hypotension
Hyperkalemia
Angioneurotic edema
Cough
-
1 points
Question 29
1.
What is the mechanism action of Zidovudine
Answer
Inhibition of nucleoside reverse transcriptase
Inhibition of DNA synthesis
Inhibition of viral particle assembly
Inhibition of RNA synthesis
Inhibition of viral proteases
1 points
Question 30
1.
Which agents using should be cautious about
or avoided while patient underwent kiney
malfunction?
Answer
Penicillins
Macrolides
-
Tetracyclines
Aminoglycosides
Chloramphenicol
1 points
Question 31
1.
The mechanism of action of Biguanides is
Answer
increase the glycagon effect
decrease insulin resistance
enhance the glucose uptake and catalyzing by peripheral
tissues
stimulating insulin release from pancreatic cells
promote the glucose to catalyze
1 points
Question 32
1.
Cardiac output is best increased by
stimulation of
Answer
-
beta1 receptors
muscarinic receptors
beta2 receptors
alpha2 receptors
alpha1 receptors
1 points
Question 33
1.
The Thioureas can be used for
Answer
hypothyroidism
diabetes
hyperthyroidism
hypogonadism
allergy
1 points
Question 34
1.
-
Which one is NOT a first-line
antituberculosis agents?
Answer
Isoniazid
Ethambutol
Rifampin
Pyrazinamide
Amikacin
1 points
Question 35
1.
The mechanism of action of Sulfonylureas is
Answer
increase the glycagon effect
decrease insulin resistance
inhibit the insulin effect
promote the glucose to catalyze
stimulating insulin release from pancreatic cells
1 points
-
Question 36
1.
Which description about Generation III
Quinolones is WRONG?
Answer
Levofloxacin is most effective vs. G germs in the family
They act against G germs by inhibiting DNA gyrase
They are chlorine derivatives of Pipemidic acid
They act against G germs by inhibiting DNA topoisomerase IV
They have strong activity against G germs
1 points
Question 37
1.
Which agent act against bacteria mainly by
interfering functions of cell membrane?
Answer
ciprofloxacin
polymyxin B
streptomycin
-
erythromycin
tetracycline
1 points
Question 38
1.
Which drug is effective against either
systemic or superficial fungal infection?
Answer
Flucytosine
Ketoconazole
Nystatin
Amphotericin B
Ribavirin
1 points
Question 39
1.
Which one in the following drug is best to
treat hypertension crisis
Answer
-
Spironolactone
Losartan
Sodium Nitroprusside
Captopril
Hydrochlorothiazide
1 points
Question 40
1.
Hypokalaemia occurs with the following drugs
Answer
Captopril
Bumetanide
Nifedipine
Carbonic anhydrase inhibitors
Spironolactone
1 points
Question 41
1.
-
Prodrug-requires activation by microsomal
enzyme system
Answer
cyclophosphamide (Cytoxan)
chlorambucil (Leukeran)
thiopeta (Thioplex)
mechlorethamine (Mustargen)
semustine (methyl CCNU)
1 points
Question 42
1.
Why the clinical use of Choloramphenicol is
limited in infectious disease?
Answer
Severe adverse effects such as irreversible marrow inhibition
Low bioavailability
Most bacteria have developed drug resistance
Low efficiency in suppressing bacteria
Severe allergic shock
-
1 points
Question 43
1.
Which one does NOT have the effect of
antiplatelet aggregation
Answer
Aspirin
Wafarin
Dipyridamole
Ridogrel
Epoprostenol
1 points
Question 44
1.
Which of the following is NOT the adverse
effects of Glucocorticoid ?
Answer
poor wound healing
asthma
-
"buffalo hump, moon face"
osteoporosis
hypertension
1 points
Question 45
1.
Omeprazole is belonged to
Answer
H1 receptor antagonists
H2 receptor antagonists
M receptor antagonists
Mucosal protective agents
H+-K+-ATPase (Proton pump) inhibitor
1 points
Question 46
1.
A 25-year-old female post-renal transplant
shows signs of acute renal allograph
-
rejection. Of the following agents, which
should be administered?
Answer
Acyclovir
Interleukin-2
Levamisole
Interferon
Cyclosporin A
1 points
Question 47
1.
By which target Aminoglycosides interfered
with protein synthesis of bacteria?
Answer
stage of peptide strands exfliation
stage of termination
all stages of protein synthesis
stage of initiation
stage of peptide strands elongation
-
1 points
Question 48
1.
The phase of the cell cycle that is resistant
to most chemotherapeutic angents and
requires increased dosage to obtain a
response is the
Answer
S phase
M phase
G0 phase
G1 phase
G2 phase
1 points
Question 49
1.
Which one in the following drugs is
preferable to use to treat Paroxysmal
supraventricular tachycardia
Answer
-
Amiodarone
Verapamil
Procainamide
Lidocaine
Atropine
1 points
Question 50
1.
Competitive inhibitor of
3-hydroxy-3-methylglutaryl coenzyme A
(HMG-CoA) reductase is
Answer
Cholestyramine
Ezetimibe
Simvastatin
Acetazolamide
Nicotinic acid
1 points
Question 51
-
1.
The effect mechanism of expectorant
Acetylcystein is
Answer
breakdown the viscous component of the sputum
decrease the protein secretion in the airway
increase airway fluid secretion
increase airway ciliary movement
decrease sputum secretion
1 points
Question 52
1.
Which of the following description about the
clinical uses of Glucocorticoid is WRONG
Answer
inhibit the growth of bacteria
anti-shock
anti-inflammatory effects
immunosuppressive effects
-
anti-allergic effect
1 points
Question 53
1.
Which drug can Increase nitric oxide (NO)
Answer
lonidine
Aldosterone Antagonists
Nifedipine
Methyldopa
Nitroprusside
1 points
Question 54
1.
Which drug is most effective against systemic
fungal infection?
Answer
Terbinafine
Nystatin
-
Clotrimazole
Amphotericin B
Griseofulvin
1 points
Question 55
1.
Which of the following drugs is the first
choice for the treatment of type I diabetes?
Answer
Angiotensin Converting Enzyme (ACE) Inhibitors
Insulin
Sulfonylureas
Acarbose
Biguanides
1 points
Question 56
1.
Which one in the following drugs is highly
efficacious diuretics
-
Answer
Spironolactone
Acetazolamide
Hydrochlorothiazide
Triamterene
Furosemide
1 points
Question 57
1.
To treat bleeding induced by Warfarin, which
drug can be used
Answer
Urokinase
Vit K
Vit B12
Dipyridamole
Protamine
1 points
Question 58
-
1.
Which agent is The 1st choice against MRSA?
Answer
Amoxicillin
Generation 1 Cephalosoprins
Vancomycin
Penicillin G
Erythromycin
1 points
Question 59
1.
Gentamicin inhibit bacterial protein
synthesis by binding
Answer
30S ribosomal particles
Messenger RNA
RNA polymerase
Peptidoglycan units in the cell wall
DNA polymerase
-
1 points
Question 60
1.
The most effective drug to inhibit gastric
acid secretion is
Answer
Calcium carbonate
Cimetidine
Proglumide
Pirenzepine
Omeprazole
1 points
Question 61
1.
Compare antibacterial characteristics of 4
generations of Cephalosporins.
Answer
Question 62
1.
-
What is the clinical uses of Calcium Channel
Blockers(CCBs).
Answer
Question 63
1.
List the adverse drug reactions (adverse
effects) of Glucocorticoids in long-term
use.
Answer
Question 64
1.
Please describe the therapeutic strategies
and drugs for Peptic Ulcer.
Answer
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