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MICROBIOLOGICAL RESULTS
STILL WAITING?
WAITING FOR MICROBIOLOGICAL TEST RESULTS FOR WFI AND PURIFIED WATER IS NOW A THING OF THE PAST
JMAR INTRODUCES
• CONSTANT WATER QUALITY AWARENESS
• REAL-TIME BIOBURDEN MEASUREMENT
• INCREASED PROCESS CONTROL
• ONLINE MINUTE BY MINUTE ANALYSIS
• IMMEDIATE MEASURABLE ROI
• LOW ENERGY CONSUMPTION (300 WATTS)
Benefits:Continuous monitoring detects biological contamination of WFI or purified water in real time
Significantly lowers costs by reducing product loss and product recalls due to contamination
Monitors effectiveness of water purification processes
Automated system offeres low mainenance and low cost of ownership
Features:Total sytem flow 100ml/min
Inspection volume rate ~ 1 ml per minute (1.4 liters per day)
Requires no consumables or reagents for detection
Automatic cleaning
KBERG CONSULTANTS
4234 MASSEY PRESERVE TRAILRALEIGH, NC 27616 USA
PHONE (910)[email protected]
STEWART JASON KOHNBERG
BioSentry’s real-time results equal real savings for
pharmaceutical manufacturers. The real-time
data provided by BioSentry has the potential to
increase productivity, reduce �nished product
release time, as well as lower lot rejection rates.
While BioSentry does not replace conventional
methods of testing , its advanced monitoring
technologies can reduce the number of overall
conventional tests needed every year resulting in
substantial consumable cost and labor savings for
manufacture rs.
BioSentry’ s compact, reagent free, and energy
e�cient design saves on operating costs around
the clock. Its multiple purchase incentives,
comprehensive training, and dedicated support
team make keep initial costs low and result in a
quick return of investment.
If you would like to learn more about BioSentry, or
discuss exactly how BioSentry can save you
money , please contact us at (858)946-6800 or visit
us on the web at www.jmar.com.
Returning Real-Time Results
No longer does the pharmaceutical industry have
to wait for microbiological test results for WFI and
puri�ed water. BioSentry not only reduces the wait
for microbial contamination results, it eliminates it.
With real-time, on-line capabilities
BioSentry allows users to
monitor the biological activity
of a water source from
anywhere in the world
at any time of day.
Whether you are across the
lab or across the globe,
BioSentry will alert you
the moment contamination occurs.
Returning Real Savings
Pharmaceutical manufacturers are �nally able to
integrate the power of state-of-the-art technology
with long standing scienti�c methods to assure
continuous water purity. JMAR’s BioSentry is the
only rapid microbiological method (RMM) of detec-
tion that o�ers real-time, on-line, monitoring for
microorganisms in process water.
Cost of capital
Net present value
Return on investment
Payback (in years)
298%
12%$2,312,057
0.29
ROI Measures
Sample Business Senerio
Reduction in Lot rejections (assumes impovement by 1 bactch)
Reduction in investigation cycle time from process excursions(manpower and Lab resources)
Loss of productivity due to line down time(assumes 1 batch produced)
Reduction in cycle time during production line restart after maintenance
Loss of productivity during production line restart(assumes 1 batch produced)
Reduction in rework, reprocessing, and repeat testing
Total Annual Benefits
Implementation �lter
Total Benefits Realized
BENEFIT DRIVERS YEAR0 1
$400,000
$50,000
$400,000
$50,000
$400,000
$30,000
$1,330,000
60%
$798,000
Initial InvestmentInitial investment (assume 3 unitis to support operstions)
Implementation Costs (Quali�cation and regulatory costs)
Ongoing support costs
Training costs
Other costs
Total Costs
$0
$0
$5,000
$5,000
$0
$10,000
$120,000
$100,000
$0
$10,000
$0
$230,000
0 1
REAL-TIME RESULTS, REAL SAVINGS
REAL-TIME RESULTS, REAL SAVINGS
KBERG CONSULTANTS(910)232-0342
www.kberg.info