Nehal N. Mehta, MD, MSCE, FAHA Page 1
National Institutes of Health, National Heart, Lung, and Blood Institute
Curriculum Vitae
Date: 11/6/2014
Nehal N. Mehta, MD, MSCE, FAHA
Address: 10 Center Drive
CRC, Room 5-5140
National Institutes of Health
Bethesda, MD 20892 USA
Phone: 301-824-0483
Fax: 301-451-7093
Email: [email protected]
Education:
1997 BA The George Washington University (Seven-Year Accelerated
Medical Program) (Neuropsychobiology)
1997 NA Oxford University (Biochemistry)
2001 MD The George Washington University Medical School
(Medicine)
2009 MSCE University of Pennsylvania, Center for Clinical Epidemiology
and Biostatistics (Genetic Epidemiology)
Postgraduate Training and Fellowship Appointments:
2001-2002 Internship in Internal Medicine, Hospital of University of
Pennsylvania
2002-2004 Residency in Internal Medicine, Hospital of University of
Pennsylvania
2004-2005 Chief Medical Resident, Hospital of the University of
Pennsylvania
2005-2007 Fellow in Cardiovascular Medicine, Hospital of the University
of Pennsylvania
2006-2007 Chief Fellow in Cardiovascular Medicine, Hospital of the
University of Pennsylvania
2007-2009 Post-doctoral Research Fellow in Cardiovascular
Medicine/Fellow in Genetic Epidemiology, Center for Clinical
Biostatistics and Epidemiology, University of Pennsylvania
2007 Course on Genetics of Diabetes, Columbia University
2007 Course on Complex Heart, Lung and Blood Disorders, The
Jackson Laboratory
2007 Course on Clinical Cardiovascular Genomics, Cold Spring
Harbor
2008 Cohort Study Conference on Cardiac Diseases, National Heart,
Lung and Blood Institute
Nehal N. Mehta, MD, MSCE, FAHA Page 2
Faculty Appointments:
2004-2005 Clinical Instructor in Medicine, University of Pennsylvania
School of Medicine
2009-2012 Instructor A in Cardiovascular Medicine, University of
Pennsylvania School of Medicine
2009-present Adjunct Scholar, Center for Clinical Biostatistics and
Epidemiology, University of Pennsylvania School of Medicine
2012-present Adjunct Assistant Professor, University of Pennsylvania
School of Medicine
2013-present
2014-present
Clinical Associate Professor of Medicine, The George
Washington University School of Medicine and Health
Sciences
Clinical Professor of Medicine, The George Washington
University School of Medicine and Health Sciences
Hospital and/or Administrative Appointments:
2007-2012 Attending Physician, Division of Cardiology, Pennsylvania
Hospital
2008-2012 Attending Cardiologist, Pennsylvania Hospital, University of
Pennsylvania
2008-2012 Director, Cardiology Advanced Practitioner Services
2009-2012 Attending Cardiologist, Hospital of the University of
Pennsylvania
2009-present Director, Inflammatory Risk, Preventive Cardiology, Hospital
of the University of Pennsylvania
2012-present Chief, Section of Inflammation and Cardiometabolic Diseases,
Cardiovascular and Pulmonary Branch, National Heart, Lung,
and Blood Institute, National Institutes of Health
Specialty Certification:
2004 American Board of Internal Medicine (Internal Medicine)
2007 National Board of Echocardiography (Level II
Echocardiography)
2007 American Society of Nuclear Cardiology (Nuclear
Cardiology)
2008 American Board of Internal Medicine (Cardiovascular
Diseases)
Licensure:
2005-Present Pennsylvania State Board of Medicine
Awards, Honors and Membership in Honorary Societies:
1991 Eagle Scouts of America Award
1995 National Collegiate Scholar
1996 Psi Chi Psychology Honors Society, The George Washington
University
Nehal N. Mehta, MD, MSCE, FAHA Page 3
1996 Phi Beta Kappa, The George Washington University
1997 Summa Cum Laude, The George Washington University
1997 Hertford College Scholar Award, Oxford University
1998 WT Gill Research Fellowship, The George Washington
University
2000 William Beaumont Research Honors Society, The George
Washington University
2001 Kane King Dodek Obstetrical Honors Society The George
Washington University
2001 MD with Distinction, The George Washington University
2005 Edward W. Holmes Resident Research Award, Hospital of the
University of Pennsylvania
2006 American College of Cardiology/Merck Award for Metabolic
Syndrome Research
2006 Basic Science Teaching Award - Best Section Leader,
University of Pennsylvania School of Medicine
2007 Nominee, Best Section Leader, University Of Pennsylvania
School of Medicine
2007 Fellow, American College of Physicians
2008 Junior Investigators Pilot Grant Award, University of
Pennsylvania Clinical Translational Research Center
2008 Finalist, Northwestern University Young Investigators Forum
2008 Fellow, American College of Cardiology
2008 Fellow Research Award, Division of Cardiovascular
Medicine, Penn Cardiovascular Institute
2009 Best abstract, Gordon Conference on Atherosclerosis
2009 Future Leader in Cardiovascular Research Award
2009 Leadership Council in Cardiovascular Medicine National
Research Award (declined due to K23)
2009 Fellow, American Heart Association
2009 Dr. Madhukar Deshmukh Research Award, Best Abstract
Clinical Research in Preventive Cardiology, American
Association of Cardiologists of Indian Origin
2009 First Prize, Northwestern University Young Investigators
Forum, Best Clinical Research
2010 Jeremiah Stammler Research Award, Northwestern University
Young Investigators Symposium, Best Faculty Research
2010 Bradley Award, Best Young Investigator, Junior Faculty,
Department of Medicine, University of Pennsylvania
2012
2014
Lasker Clinical Research Scholar Award, The National
Institutes of Health, National Heart, Lung, and Blood Institute
IPC Councilor, International Psoriasis Council
Memberships in Professional and Scientific Societies and Other Professional Activities:
National:
1997-Present American Medical Association (Member)
Nehal N. Mehta, MD, MSCE, FAHA Page 4
1999-Present American College of Physicians (Member (1999-present); Fellow (2007-present)
2004-Present American Heart Association Council on Prevention/Epidemiology (Member); Chair,
Early Career Committee (2010-2012)
2005-Present American College of Cardiology (Fellow)
2005-Present American Society of Echocardiography (Member)
2007-Present American Society of Nuclear Cardiology (Member)
2010-Present American Heart Association Awards & Lectures Committee (Member)
2011-Present
2014-Present
2014-Present
2014-2016
2014-Present
American Heart Association Research Committee (Member)
European Society for Translational Medicine (Member)
National Psoriasis Foundation (NPF) Medical Board (Member)
American Heart Association Awards & Lectures Committee (Chair)
American College of Cardiology ACC.15 Program Committee (Member)
Local:
1997-2001 Medical Society of Washington DC (Member)
2001-2012 Pennsylvania Medical Society (Member)
Reviewer/Editorial Positions:
2005-Present Editorial Staff, First Aid Clinical Cases, Cardiovascular Series
2006-Present Reviewer, Journal of the Cardiometabolic Syndrome
2006-Present Reviewer, International Journal of Cardiology
2006-Present Reviewer, Circulation
2006-Present Reviewer, American Journal of Cardiology
2006-Present Consulting Editor, Handheld Books, Cardiovascular Series
2008-Present Reviewer, Journal of American College of Cardiology
2008-Present Reviewer, Journal of Pharmacoepidemiology
2009-Present Reviewer, J of European Acad of Derm and Venereology
2009-Present Reviewer, Journal of Rheumatology
2009-Present Reviewer, Journal of Obesity
2009-Present Reviewer, Circulation CV Genetics
2009-Present Reviewer, PLoS One
2010-Present Reviewer, British Journal of Dermatology
2010-Present Reviewer, Abstracts of the American Heart Association
2010-Present Reviewer, Abstracts of the American College of Cardiology
2010-Present Reviewer, Atherosclerosis
2010-Present Reviewer, British Medical Journal
2010-Present Reviewer, American Heart Journal
2011-Present Reviewer, Journal of Clinical Lipidology
2011-Present Reviewer, JAMA
2011-Present Reviewer, Abstracts of the AHA Epidemiology Meeting
2011-Present Associate Editor, BMC Cardiovascular Diseases
2011-Present Associate Editor, Journal of Cardiovascular Diseases
2012-Present
Section Editor, Journal of Translational Medicine, Section of
Cardiovascular, Lipoprotein and Metabolic Translation
2012-Present Editorial Board Member, Heart Insight Magazine
Nehal N. Mehta, MD, MSCE, FAHA Page 5
2012-Present
2012
2013 Abstract Reviewer, American Heart Association:
Epidemiology and Prevention/Nutrition, Physical Activity and
Metabolism Scientific Sessions (EPI/NPAM)
Reviewer, ACC.14 Program Committee
2013
2013 National Psoriasis Foundation Discovery and Translational
Grant Application Reviewer
2013 Editorial Board Member, JSM Genetics and Genomics, Journal of
Immunology & Clinical Research
2013
2013-2015
2013-present
2013-present
2013-present
2013-present
2014-present
2014-present
2014-present
2014-present
2014-present
2014-present
2014-present
2014-present
2014-present
2014-present
2014-present
2014-present
Reviewer, American Heart Association’s Genomics & Translational
Epidemiology & Observational Epidemiology – Population Science
1 Peer Review Committee, Fall 2013
Epidemiology & Prevention Council’s Prevention Science
Committee (Member)
Editorial Board Member, Insights of Translational Medicine
Editorial Board Member, World Journal of Cardiology
Editorial Board Member, Austin Journal of Immunology
Editorial Board Member, Journal of Cardiology and Therapy
Editorial Board Member, Journal of Geriatric Cardiology
Grant reviewer, The Netherlands Organization for Health Research
and Development (ZonMw)
Editorial Board Member, International Scholarly Research Notices
Editorial Board Member, International Journal of Cardiology and
Research
Editorial Board Member, Insight Knowledge
Reviewer, American Heart Association for Strategically Focused
Network on Prevention
Editorial Board Member, Journal of Experimental Dermatology and
Clinical Research
Editorial Board Member, Journal of Medical Genomics and
Biomarkers (MGB)
Editorial Board Member, American College of Cardiology
Prevention Clinical Topic Collection
Editorial Board Member, Global Journal of Obesity, Diabetes, and
Metabolic Syndrome
Editorial Board Member, Journal of Immunology and
Immunotherapeutics
Editorial Board Member, CYTOKINE
Academic and Institutional Committees:
2001-2002 Intern Steering Committee, Department of Medicine, Hospital of the
University of Pennsylvania
2002-2005 Resident Steering Committee, Department of Medicine, Hospital of
the University of Pennsylvania
2008-Present Director, Cardiology Advanced Practitioner Service
Nehal N. Mehta, MD, MSCE, FAHA Page 6
Major Academic and Clinical Teaching Responsibilities:
2000-2001 Clinical instructor to 1st and 2nd year students in physical
examination and history taking.
2000 Internal Medicine Curriculum Committee representative to develop
clinical skills; reviewed a chest x-ray class and EKG class.
2001 EKG reading skills workshop for the 3rd year clinical clerks.
2002 Department of Medical Genetics Grand Rounds, University of
Pennsylvania, Conference on Hereditary Hemorrhagic
Telangiectasia, "Pulmonary Venous Aneurysms Detected by Time-
Resolved MRA"
2002 EKG digitizer for medical resident and cardiovascular fellow
conferences under Ralph Verdino, MD.
2004-2012 Lecturer, Department of Ob/Gyn, peri-operative cardiac diseases
2004-2005 Chief Medical Resident, Hospital of the University of Pennsylvania
2005 Department of Medicine Grand Rounds, University of Pennsylvania.
"38th Tri-annual Chief Medical Resident Clinical Pathological
Conference"
2005 Division of Cardiology and Cardiothoracic Surgery, University of
Pennsylvania. "Massive Pericardial Effusion 3 months after aortic
root surgery"
2005-2012 Medical student clinical cardiovascular auscultation seminar,
"Harvey", School of Medicine, University of Pennsylvania
2006 Division of Cardiology and Cardiothoracic Surgery, University of
Pennsylvania. "Atrioventricular Septal Defect"
2006 Division of Cardiology and Cardiothoracic Surgery, University of
Pennsylvania. "Ischemic mitral regurgitation"
2006 Division of Cardiology and Cardiothoracic Surgery, University of
Pennsylvania. "Management of Malignant Pericardial Effusion"
2006-2012 Small-group leader for 14 lectures yearly, Basic Science
Cardiovascular Module, School of Medicine, University of
Pennsylvania
2010-2012 Small-group leader, Penn Epidemiology course, first-year medical
students
Lectures by Invitation:
Jun, 2005 "Training at the Hospital of the University of Pennsylvania: Why
cardiology?", Penn Medicine Board of Trustees; Philadelphia, PA
Jun, 2005 "Adiposity and pro-atherosclerotic responses to an Innate Immune
Challenges in Humans", University of Pennsylvania Holmes
Research Day; Philadelphia, PA
Apr, 2006 "Modulation of the Insulin Signaling Pathway in Human
Inflammation", Atherosclerosis, Thrombosis and Vascular Biology
of the American Heart Association; Denver CO
Nov, 2006 "The Effect of PKC-Inhibition on Macrovascular Function in
Patients with Type 2 Diabetes", American Heart Association;
Chicago IL
Nehal N. Mehta, MD, MSCE, FAHA Page 7
Jun, 2007 "Understanding Diabetic Coronary Risk", Atlantic United Coder and
Abstracter Conference Keynote Speaker; Philadelphia, PA.
Nov, 2007 "Very-low Dose Endotoxemia Induces Insulin Resistance in the
Absence of Clinical Inflammatory Responses", American Heart
Association; Orlando FL
Jun, 2008 "Diabetic Coronary Disease and Complications", Atlantic City
Medical Center Medical Grand Rounds; Atlantic City, NJ
Mar, 2009 "Human Translational Studies of a Novel Atherosclerosis Locus",
Future Leaders of Cardiovascular Research; Orlando, FL
Jun, 2009 "A novel GWAS Atherosclerosis Locus Regulates Plasma CXCL12
levels", Gordon Conference on Atherosclerosis; Tilton NH
Jun, 2009 "Management of Cardiac Disease in Impaired Glucose Tolerance",
Atlantic City Medical Center Medical Grand Rounds; Atlantic City,
NJ
Oct, 2009 "Human Translational Studies of Inflammation, Insulin Resistance
and Atherosclerosis", Cardiovascular Medicine Grand Rounds;
Philadelphia PA
Oct, 2009 "Human Translational Studies of Inflammation, Psoriasis and
Atherosclerosis", The Murdough Symposium on Psoriasis, Case
Western University; Cleveland OH
Oct, 2009 "Psoriasis and Cardiovascular Care: An Innovative and Integrated
Approach to Risk Stratification and Risk Reduction", Murdough
Symposium on Psoriasis, Cleveland OH
Nov, 2009 "A novel GWAS Atherosclerosis Locus Regulates Plasma CXCL12
levels", American Heart Association' Orlando FL
Feb, 2010 "Human Translational Studies of CXCL12", Cardiovascular
Institute, University of Pennsylvania, Philadelphia PA
Sep, 2010 "Convergence of CXCL12 and PHACTR-1: Novel GWAS Signals
for MI", Northwestern Young Investigators Forum, Chicago, IL
Sep, 2010 "Cardiovascular Care of Patients with Psoriasis", Case Western
University Murdough Symposium, Cleveland, OH
Oct, 2010 "Genomic Variation, Inflammation and Vascular Disease",
Inflammation Symposium, University of Medicine and Dentistry of
New Jersey, Newark, NJ
Nov, 2010 "Convergence of CXCL12 and PHACTR-1: Novel GWAS Signals
for MI", Amaerican Heart Association Young Investigator Award
Finalist, Chicago, IL
Mar, 2011 "Evidence Based Practice of Advanced Inflammatory and
Lipoprotein Testing", American Occupational Medicine Conference,
Washington, DC
Jun, 2011 "Detection of Subclinical Systemic and Vascular Inflammation in
Psoriasis using FDG PET/CT", Division of Division of
Allergy/Immunology, Rheumatology and Department of
Dermatology (AIR) Grand Rounds, SUNY Rochester, Rochester,
NY
Nehal N. Mehta, MD, MSCE, FAHA Page 8
Jun, 2011 "FDG PET/CT Detects Vascular Inflammation in Vivo in Psoriasis",
Updates in Dermatology, New York University Department of
Dermatology, New York, NY
Jun, 2011 "In Vivo Modulation of CXCL12 in Adipose and Plasma", Gordon
Conference on Atherosclerosis, Newport, RI
Sept, 2011 “Human Translational Studies of Inflammation and Cardiometabolic
Diseases”, Lasker Scholar Seminar, National Institutes of Health
Oct, 2011 "Human Translational Studies of Inflammation and Atherosclerosis:
From Epidemiology and Back", Johns Hopkins University Welch
Center Grand Rounds, Baltimore, MD
Jul, 2012 “Psoriasis and Cardiovascular Risk”, Dermatology Resident Grand
Rounds, National Navy Medical Center, Bethesda, MD
Sept, 2012
Oct, 2012
Oct, 2012
Jan, 2013
“Advanced Cardiometabolic Phenotyping in Psoriasis: Links
between Psoriasis and CV Risk”, World Psoriasis Congress,
Stockholm, Sweden
“Understanding Psoriasis: Why a Cardiologist”, National Psoriasis
Foundation, Bethesda Country Club, Bethesda, MD
“Human Translational Studies of Inflammation and Cardiometabolic
Diseases: From Epidemiology and Back”, Extramural NHLBI,
Bethesda, MD
“Inflammation and Cardiometabolic Diseases: Associative or
Causal”, George Washington University CV Grand Rounds,
Washington, DC
Nehal N. Mehta, MD, MSCE, FAHA Page 9
Jan, 2013
Jan, 2013
Jan, 2013
Jan, 2013
Feb, 2013
Mar, 2013
Mar, 2013
Mar, 2013
Apr, 2013
Apr, 2013
Jun, 2013
Jun, 2013
Jun, 2013
Jul, 2013
“Human Translation of Inflammation and Cardiovascular Disease”,
George Washington University Grand Rounds, Washington, DC
“Human Translational Studies of Inflammation and Cardiometabolic
Diseases: In Vivo Studies and Beyond”, Weekly Inflammation and
Immunity Seminar Series, Center for Cancer Research, Frederick,
MD
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, Eli Lilly and Company, Indianapolis, IN
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, Novartis Pharmaceuticals Co., East Hanover, NJ
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, Johns Hopkins University Dermatology Grand Rounds,
Baltimore, MD
“A Comparison of Vascular Inflammation in Rheumatoid Arthritis,
Psoriasis and Healthy Controls by FDG-PET/CT: A Pilot Study,”
American College of Cardiology 62nd
Annual Scientific Session, San
Francisco, CA
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, University of Maryland Dermatology Grand Rounds,
College Park, MD
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, Baylor University Dermatology Grand Rounds, Dallas,
TX
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, George Washington University Nephrology Grand
Rounds, Washington, DC
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, NEDS Didactic Symposium, University of Connecticut
Health Center Department of Dermatology, Farmington, CT
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, Case Western University, Cleveland, OH
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, Cardiovascular Imaging Research Seminar, University of
Pennsylvania, Philadelphia, PA
“Psoriasis and Cardiometabolic Disease: Inflammation at the Heart
of the Matter?”, Canadian Dermatology Association 2013 Annual
Meeting, Toronto, CA
“Human Translational Studies of Inflammation and Cardiometabolic
Disease”, Visiting Professor, Northwestern University Department
of Dermatology Grand Rounds, Chicago, IL
Nehal N. Mehta, MD, MSCE, FAHA Page 10
Jul, 2013
Jul, 2013
Sept, 2013
Oct, 2013
Nov, 2013
Feb, 2014
Feb, 2014
March, 2014
April, 2014
June, 2014
Keynote Speaker, NHLBI K Award Investigator’s Meeting,
Bethesda, MD
Persistent Inflammation and Immune Activation in HIV-Infected
Children and Youth on Effective ART, NICHD Offices, NIH,
Rockville, MD
Pennsylvania Regional Occupational Medicine Meeting,
Philadelphia, PA
Androgen Excess Meeting, Newport, RI
Key Note: “Inflammation and Cardiometabolic Diseases”,
International Psoriasis Council, Boston, MA
“Inflammation and Cardiometabolic Diseases: An Attempt to
Dissect Causality and Association”, University of Michigan Grand
Rounds, Ann Arbor, MI
National Institute of Arthritis and Musculoskeletal and Skin
Diseases Fellows talk
"Impact of psoriasis severity on hypertension control: a population-
based study in the United Kingdom", American Academy of
Dermatology Meeting, Denver, CO
“Inflammation and Cardiometabolic Diseases: An Attempt to
Dissect Causality and Association”, University of Pittsburgh
Medical Center Grand Rounds, Pittsburgh, PA
“Incidence of Major Adverse Cardiovascular Events with
Secukinumab: A Pooled Analysis of Data from Phase 2 and 3
Clinical Trials in Psoriasis”, Federation of Clinical Immunology
Societies, Chicago, IL
Organizing Roles in Scientific Meetings:
2008 American College of Physicians Pennsylvania State Chapter
Executive Committee
Harrisburg, PA
Nov, 2009 American Heart Association Council of Epidemiology and
Prevention, Early Career Symposium Booth
Orlando FL
2009 American Heart Association, Council on Epidemiology and
Prevention 39th Annual Meeting, Early Career Annual Meeting
Planning Committee
Marlton, FL
Nov, 2010 Moderator, Early Career Committee Workshop, American Heart
Association Scientific Sessions
Chicago, IL
Nehal N. Mehta, MD, MSCE, FAHA Page 11
Mar, 2011 Moderator, Obesity and Cardiovascular Disease, American College
of Cardiology Sessions
New Orleans, LA
Nov, 2011 Moderator, Functional Genomics and Translational Biology (FGTB)
of the American Heart Association Early Career Session
Orlando, FL
2012 Organizing Member, American Heart Association
NPAM/Epidemiology Annual Meeting Sessions 2012
TBD
Nov, 2012 Moderator, Early Career Session, American Heart Association
Mar, 2013 Moderator, Traditional or New Risk Factors, NPAM/Epidemiology
Annual Scientific Sessions, New Orleans, LA
Mar, 2013 Moderator, “Acute Coronary Syndromes: Basic II”, American
College of Cardiology 62nd
Annual Scientific Sessions, San
Francisco, CA
Bibliography:
Research Publications, peer reviewed (print or other media):
1. Windsor J, Santoian EC, Tarazona N, Mehta NN, Malosky SA and Dennis CA: Local
and Systemic Steroids in a Swine Model of Arterial Injury. Journal of
Investigative Medicine 43(2): 271-3, Apr 1995.
2. Ferrari VA, Mehta NN, Soulen M, Roberts DA, St John SM: Images in cardiovascular
medicine. Pulmonary venous aneurysms in hereditary hemorrhagic telangiectasia
detected by 3-dimensional magnetic resonance angiography. Circulation 108(17):
e122-3, Oct 2003. PMCID: PMC1470768
3. Mehta NN, Loria PM, Hobert O: A genetic screen for neurite outgrowth mutants in
Caenorhabditis elegans reveals a new function for the F-box ubiquitin ligase
component LIN-23. Genetics 166(3): 1253-67, Mar 2004. PMCID: PMC1470768
4. Mehta, NN. Romanelli, J. Sutton, M, Graham St J.: Native aortic valve vegetative
endocarditis with Cunninghamella. European Journal of Echocardiography 5(2):
156-8, Mar 2004. PMCID: PMC1470768
5. Reilly MP, Wolfe ML, Rhodes T, Girman C, Mehta NN, Rader DJ: Measures of
insulin resistance add incremental value to the clinical diagnosis of metabolic
syndrome in association with coronary atherosclerosis. Circulation 110(7): 803-9,
Aug 2004. PMCID: PMC2218847
6. Mehta NN and Reilly MP. : Assessment of Cardiovascular Risk in the HAART-
Treated HIV-1 Population. HIV Clinical Trials 6(1): 5-24, Jan/Feb 2005.
7. Chokshi, R. Openshaw, J. Mehta, NN. Mohler, E 3rd.: Purple glove syndrome
following intravenous phenytoin administration. Vascular Medicine 12(1): 29-31,
Feb 2007. PMCID: PMC2218847
Nehal N. Mehta, MD, MSCE, FAHA Page 12
8. Anderson PD, Mehta NN, Wolfe ML, Hinkle ChC, Pruscino L, Comiskey LL, Tabita-
Martinez J, Sellers KF, Rickels MR, Ahima RS, Reilly MP: Innate immunity
modulates adipokines in humans. The Journal of clinical endocrinology and
metabolism 92(6): 2272-9, Jun 2007. PMCID: PMC2218847
9. Nolan A, Weiden M, Kelly A, Hoshino Y, Hoshino S, Mehta NN, Gold JA: CD40 and
CD80/86 act synergistically to regulate inflammation and mortality in
polymicrobial sepsis. American journal of respiratory and critical care medicine
177(3): 301-8, Feb 2008. PMCID: PMC2218847
10. Qasim A, Mehta NN, Tadesse MG, Wolfe ML, Rhodes T, Girman C, Reilly MP:
Adipokines, insulin resistance, and coronary artery calcification. Journal of the
American College of Cardiology 52(3): 231-6, Jul 2008. PMCID: PMC2712798
11. Mehta NN, Sheetz M, Price K, Comiskey L, Amrutia S, Iqbal N, Mohler ER,
Reilly MP: Selective PKC Beta Inhibition with Ruboxistaurin and Endothelial
Function in Type-2 Diabetes Mellitus. Cardiovasc Drugs Ther 23(1): 17-24, Feb
2009. PMCID: 18949545
12. Mehta NN, Sheetz M, Price K, Comiskey L, Amrutia S, Iqbal N, Mohler ER, Reilly
MP: Selective PKC beta inhibition with ruboxistaurin and endothelial function in
type-2 diabetes mellitus. Cardiovascular drugs and therapy / sponsored by the
International Society of Cardiovascular Pharmacotherapy 23(1): 17-24, Feb 2009.
PMCID: PMC3088108
13. Martin SS, Qasim AN, Mehta NN, Wolfe M, Terembula K, Schwartz S, Iqbal N,
Schutta M, Bagheri R, Reilly MP: Apolipoprotein B but not LDL cholesterol is
associated with coronary artery calcification in type 2 diabetic whites. Diabetes
58(8): 1887-92, Aug 2009. PMCID: PMC2712798
14. Shah R, Lu Y, Hinkle CC, McGillicuddy FC, Kim R, Hannenhalli S, Cappola TP,
Heffron S, Wang X, Mehta NN, Putt Mary, Reilly Muredach P: Gene profiling of
human adipose tissue during evoked inflammation in vivo. Diabetes 58(10):
2211-9, Oct 2009. PMCID: PMC2750231
15. Mehta NN, McGillicuddy FC, Anderson PD, Hinkle CC, Shah R, Pruscino L, Tabita-
Martinez J, Sellers KF, Rickels MR, Reilly MP: Experimental endotoxemia
induces adipose inflammation and insulin resistance in humans. Diabetes 59(1):
172-81, Jan 2010. PMCID: PMC2797919
16. Mehta NN, McGillicuddy F, Anderson P, Hinkle C, Shah R, Pruscino L, Tabita-
Martinez J, Sellers K, Rickels MR, Reilly MP : Experimental Endotoxemia
Induces Adipose Inflammation and Insulin Resistance in Humans. Diabetes 59(1):
S1-8, Jan 2010 Notes: Supplemental data. PMCID: 19794059
Nehal N. Mehta, MD, MSCE, FAHA Page 13
17. Eraso LH, Ginwala N, Qasim AN, Mehta NN, Dlugash R, Kapoor S, Schwartz S,
Schutta M, Iqbal N, Mohler ER, Reilly MP: Association of lower plasma fetuin-a
levels with peripheral arterial disease in type 2 diabetes. Diabetes care 33(2): 408-
10, Feb 2010. PMCID: PMC2809293
18. Qasim AN, Martin SS, Mehta NN, Wolfe ML, Park J, Schwartz S, Schutta M, Iqbal
Nayyar, Reilly MP: Lipoprotein(a) is strongly associated with coronary artery
calcification in type-2 diabetic women. International journal of cardiology 150(1):
17-21, Mar 2010. PMCID: PMC2988112
19. Gelfand JM, Azfar RS, Mehta NN: Psoriasis and cardiovascular risk: strength
innumbers. Journal of Investigative Dermatology 130(4): 919-922, April 2010.
20. Mehta NN, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM: Patients with
severe psoriasis are at increased risk of cardiovascular mortality: cohort study
using the General Practice Research Database. European heart journal 31(8):
1000-6, Apr 2010. PMCID: PMC2894736
21. Bagheri R, Qasim AN, Mehta NN, Terembula K, Kapoor S, Braunstein S, Schutta M,
Iqbal N, Lehrke M, Reilly MP: Relation of plasma fatty acid binding proteins 4
and 5 with the metabolic syndrome, inflammation and coronary calcium in
patients with type-2 diabetes mellitus. The American journal of cardiology
106(8): 1118-23, Oct 2010. PMCID: PMC3086062
22. Shen H, Bielak LF, Ferguson JF, Streeten EA, Yerges-Armstrong LM, Liu J, Post W,
O'Connell JR, Hixson JE, Kardia SL R, Sun YV, Jhun MA, Wang X, Mehta NN,
Li M, Koller DL, Hakonarson H, Keating BJ, Rader DJ, Shuldiner AR, Peyser
PA, Reilly MP, Mitchell BD: Association of the vitamin D metabolism gene
CYP24A1 with coronary artery calcification. Arteriosclerosis, thrombosis, and
vascular biology 30(12): 2648-54, Dec 2010. PMCID: PMC2988112
23. Qasim AN, Budharaju V, Mehta NN, St Clair C, Farouk S, Braunstein S, Schutta M,
Iqbal N, Rader DJ, Reilly MP: Gender differences in the association of C-reactive
protein with coronary artery calcium in type-2 diabetes. Clinical endocrinology
74(1): 44-50, Jan 2011. PMCID: PMC3005137
24. Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney
JM, Knouff CW, Thompson JR, Horne BD, Stewart AFR, Assimes TL, Wild PS,
Allayee H, Nitschke PL, Patel RS, Martinelli N, Girelli D, Quyyumi AA,
Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S,
Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ:
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and
association of ABO with myocardial infarction in the presence of coronary
atherosclerosis: two genome-wide association studies. Lancet 377(9763): 383-92,
Jan 2011. PMCID: PMC3086062
Nehal N. Mehta, MD, MSCE, FAHA Page 14
25. Wade AN, Fedyna S, Mehta NN, St Clair C, Ginwala N, Krishna RK, Qasim AN,
Braunstein S, Iqbal N, Schutta MH, Reilly MP: Type 2 diabetes does not attenuate
racial differences in coronary calcification. Diabetes research and clinical practice
91(1): 101-7, Jan 2011. PMCID: PMC3086062
26. Martin SS, Qasim AN, Wolfe M, St Clair C, Schwartz S, Iqbal N, Schutta M, Bagheri
R, Mehta NN, Rader DJ, Reilly MP: Comparison of high-density lipoprotein
cholesterol to apolipoprotein A-I and A-II to predict coronary calcium and the
effect of insulin resistance. The American journal of cardiology 107(3): 393-8,
Feb 2011. PMCID: PMC3086062
27. Mehta NN, Krishnamoorthy P, Martin SS, St Clair C, Schwartz S, Iqbal N,
Braunstein S, Schutta M, Rader DJ, Reilly MP: Usefulness of insulin resistance
estimation and the metabolic syndrome in predicting coronary atherosclerosis in
type 2 diabetes mellitus. The American journal of cardiology 107(3): 406-11, Feb
2011. PMCID: PMC3040419
28. Mehta NN, Li M, William D, Khera AV, Derohannessian S, Qu L, Ferguson JF,
McLaughlin C, Shaikh LH, Shah R, Patel PN, Bradfield JP, He J, Stylianou IM,
Hakonarson H, Rader DJ, Reilly MP: The novel atherosclerosis locus at 10q11
regulates plasma CXCL12 levels. European heart journal 32(8): 963-71, Apr
2011. PMCID: PMC3076669
29. Beheshti M, Saboury B, Mehta NN, Torigian DA, Werner T, Mohler E, Wilensky R,
Newberg AB, Basu S, Langsteger W, Alavi A: Detection and global
quantification of cardiovascular molecular calcification by fluoro18-fluoride
positron emission tomography/computed tomography--a novel concept. Hellenic
journal of nuclear medicine 14(2): 114-20, May-Aug 2011. PMCID:
PMC3146037
30. Mehta NN, Yu Y, Saboury B, Foroughi N, Krishnamoorthy P, Raper A, Baer A,
Antigua J, Van Voorhees AS, Torigian DA, Alavi A, Gelfand JM: Systemic and
Vascular Inflammation in Patients With Moderate to Severe Psoriasis as
Measured by [18F]-Fluorodeoxyglucose Positron Emission Tomography-
Computed Tomography (FDG-PET/CT): A Pilot Study. Archives of dermatology.
147(9): 1031-9, 2011 Sept. Notes: e pub ahead of print May 2011. PMCID:
PMC3158301
31. Shah R, Hinkle CC, Ferguson JF, Mehta NN, Li M, Qu L, Lu Y, Putt ME, Ahima RS,
Reilly MP: Fractalkine is a novel human adipochemokine associated with type 2
diabetes. Diabetes 60(5): 1512-8, May 2011. PMCID: PMC3292325
Nehal N. Mehta, MD, MSCE, FAHA Page 15
32. Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB,
Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann
H, Diemert P, Cupples AL, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE,
Voight BF, Kuulaasma K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB,
Demissie S, Proust C, König IR, Wichmann H-E, Reinhard W, Hoffmann MM,
Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu LL, El Mokthari NE,
Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W,
Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander
K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H,
Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T,
Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JCM, Uitterlinden AG,
Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP,
O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L,
Salomaa V, Munzel T, Ziegler A, Blankenberg S: A Genome-wide Association
Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease.
Circulation. Cardiovascular genetics 4(4): 403-12, May 2011. PMCID:
PMC3157552
33. Hasan R, GN, Shah R, KD, Wilensky R, Mehta NN: Quantitative Angiography of
Coronary Artery Disease in South Asians Reveals Differences in Vessel Size and
Disease Severity Compared to Caucasians. American Journal of Cardiovascular
Diseases 1(1), Jun 2011 Notes: in press.
34. Mehta NN & Rader DJ: Imaging with Indocyanine Green: Light at the End of the
Catheter? Cell Metabolism Jul 2011 Notes: in press, accepted June 18th, 2011.
35. Beheshti M, Saboury B, Mehta NN, Torigian DT, Werner T, Mohler ER, Wilensky R,
Newberg A, Basu S, Langsteger W, Alavi A: Detection and Global Quantification
of Cardiovascular Molecular Calcification by 18F-Fluoride PET/CT: A Novel
Concept Hellenic Journal of Nuclear Medicine Aug 2011 Notes: in press,
accepted June 15, 2011.
36. Mehta NN, Yu Y, Pinnelas R, Krishnamoorthy P, Shin DB, Troxel AB, Gelfand JM:
Attributable risk estimate of severe psoriasis on major cardiovascular events. The
American journal of medicine 124(8): 775.e1-6, Aug 2011. PMCID:
PMC3146037
37. Mehta NN, Yu Y, Pinnelas R, Krishnamoory PK, Shin DB, Troxel AB, Gelfand JM:
Attributable Risk Estimate of Psoriasis on Major Adverse Cardiovascular Events.
American Journal of Medicine Aug 2011 Notes: in press August 2011, accepted
May 20, 2011.
Nehal N. Mehta, MD, MSCE, FAHA Page 16
38. Kimball AB, Szapary P, Mrowietz U, Reich K, Langley RG, You Y, Hsu Yielding
NM, Rade DJ, Mehta NN: Underdiagnosis and undertreatment of cardiovascular
risk factors in patients with moderate-to-severe psoriasis. Journal of the American
Academy of Dermatology 67(1):76-85, Jul 2012. Notes: Epub ahead of print Oct
2011.
39. Kimball AB, Szapary P, Mrowietz U, Reich K, Langley RG, You Y, Hsu M-C,
Yeilding N, Rader DJ, Mehta NN: Underdiagnosis and undertreatment of
cardiovascular risk factors in patients with moderate to severe psoriasis. Journal
of the American Academy of Dermatology 67(1): 76-85, Oct 2011. PMCID:
PMC3278499
40. Hasan RK, Ginwala NT, Shah RY, Kumbhani DJ, Wilensky RL, Mehta NN:
Quantitative angiography in South Asians reveals differences in vessel size and
coronary artery disease severity compared to Caucasians. American journal of
cardiovascular disease 1(1): 31-7, 2011. PMCID: PMC3253512
41. Langan SM, Seminara, NM, Shin, DB, Troxel A, Kimmel SE, Mehta NN, Margolis
DJ, and Gelfand JM. : Prevalence of metabolic syndrome in patients with
psoriasis: A population-based study in the United Kingdom. Journal of
Investigative Dermatology 132(3 Pt 1):556-62, Mar 2012. Notes: Epub ahead of
print Nov 2011.
42. Ferguson JF, Hinkle CC, Mehta NN, Bagheri R, Derohannessian SL, Shah R,
Mucksavage MI, Bradfield JP, Hakonarson H, Wang X, Master SR, Rader DJ, Li
M, Reilly MP: Translational studies of lipoprotein-associated phospholipase
Aâ‚in inflammation and atherosclerosis. Journal of the American College of
Cardiology 59(8): 764-72, Feb 2012. PMCID: PMC3285416
43. de la Llera MM, McGillicuddy FC, Hinkle CC, Byrne M, Joshi MR, Nguyen V,
Tabita-Martinez J, Wolfe ML, Badellino K, Pruscino L, Mehta NN, Asztalos BF,
Reilly MP: Inflammation modulates human HDL composition and function in
vivo. Atherosclerosis 222(2): 390-4, Jun 2012. Notes: Epub ahead of print Feb
2012. PMCID: PMC3361641
44. Langan SM, Seminara NM, Shin DB, Troxel AB, Kimmel SE, Mehta NN, Margolis
DJ, Gelfand JM: Prevalence of metabolic syndrome in patients with psoriasis: a
population-based study in the United Kingdom. The Journal of investigative
dermatology 132(3 Pt 1): 556-62, Mar 2012. PMCID: PMC3278499
45. Mehta NN, Torigian DA, Gelfand JM, Saboury B, Alavi A: Quantification of
Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F]
Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography
(FDG-PET/CT). Journal of visualized experiments (63):e3777, May 2012.
Nehal N. Mehta, MD, MSCE, FAHA Page 17
46. Mehta NN, Heffron SP, Patel PN, Ferguson J, Shah RD, Hinkle CC, Krishnamoorthy
P, Shah R, Tabita-Martinez J, Terembula K, Master SR, Rickels MR, Reilly MP:
A human model of inflammatory cardio-metabolic dysfunction; a double blind
placebo-controlled crossover trial. Journal of Translational Medicine 10(1): 124,
Jun 2012.
47. Mehta NN, Krishnamoorthy P, Yu Y, Khan O, Raper A, Van Voorhees A, Troxel
AB, Gelfand JM: The impact of psoriasis on 10-year Framingham risk. Journal of
the American Academy of Dermatology 67(4):796-8, Oct 2012. Notes: Epub
ahead of print Jun 2012.
48. Baker JF, Mehta NN, Baker DG, Toedter G, Shults J, Von Feldt JM, Leonard MB:
Vitamin D, Metabolic Dyslipidemia, and Metabolic Syndrome in Rheumatoid
Arthritis. The American Journal of Medicine 125(10):1036.e9-1036.e15, Oct
2012. Notes: Epub ahead of print Jul 2012.
49. Gaieski DF, Goldman JD, Holtzman DL, Shoff WH, Shepherd SM, Mehta NN, Goyal
M: Algid malaria treated with early goal-directed therapy. The American Journal
of Emergency Medicine 31(1):263.e5-263.e10, Jan 2013. Notes: Epub ahead of
print Jul 2012.
50. Mehta NN, Li R, Krishnamoorthy P, Yu Y, Farver W, Rodrigues A, Raper A, Wilcox
M, Baer A, Derohannesian S, Wolfe M, Reilly MP, Rader DJ, Vanvoorhees A,
Gelfand JM: Abnormal lipoprotein particles and cholesterol efflux capacity in
patients with psoriasis. Atherosclerosis 224(1):218-21, Sept 2012. Notes: Epub
ahead of print Jul 2012.
51. Shah R, Hinkle CC, Haris L, Shah R, Mehta NN, Putt ME, Reilly MP: Adipose
Genes Down-Regulated During Experimental Endotoxemia Are Also Suppressed
in Obesity. The Journal of clinical endocrinology and metabolism 97(11):E2152-
9, Nov 2012. Notes: Epub ahead of print Aug 2012.
52. Mulvey CK., Ferguson JF., Tabita-Martinez J, Kong S, Shah RY., Patel PN., Master
SR., Usman MHU., Propert KJ., Shah R, Mehta NN., Reilly MP.: Peroxisome
Proliferator–Activated Receptor-α Agonism With Fenofibrate Does Not Suppress
Inflammatory Responses to Evoked Endotoxemia. J Am Heart Assoc
1(4):e002923, Aug 2012.
Nehal N. Mehta, MD, MSCE, FAHA Page 18
53. Mehta NN. Journal of Translational Medicine introduces a new section of
Cardiovascular, Metabolic and Lipoprotein Translation. J of Translational
Medicine 10(1):203, Sept 2012. Epub Ahead.
54. Yu Y, Sheth N, Krishnamoorthy P, Saboury B, Raper A, Baer A, Ochotony R,
Doveikis J, Derohannessian S, Voorhees AS, Torigian DA, Alavi A, Gelfand JM,
Mehta NN. Aortic vascular inflammation in psoriasis is associated with HDL
particle size and concentration: a pilot study. Am J Cardiovasc Dis 2(4):285-92,
Oct 2012.
55. Ogdie A, Langan S, Love T, Haynes K, Shin D, Seminara N, Mehta NN, Troxel A,
Choi H, Gelfand JM. Prevalence and treatment patterns of psoriatic arthritis in
the United Kingdom. Rheumatology (Oxford) Dec 2012. Epub Ahead.
56. Mehta NN. Large-scale association analysis provides insights into the genetic
architecture and pathophysiology of type 2 diabetes mellitus. Circ Cardiovasc
Genet 5(6):708-10, Dec 2012.
57. Bose S, Krishnamoorthy P, Varanasi A, Nair J, Schutta M, Braunstein S, Iqbal N,
Schwartz S, Clair CS, Master SR, Rader DJ, Reilly MP, Mehta NN.
Measurement of waist circumference predicts coronary atherosclerosis beyond
plasma adipokines. Obesity 21(1):E118-23, Jan 2013.
Nehal N. Mehta, MD, MSCE, FAHA Page 19
58. Ferguson JF, Patel PN, Shah RY, Mulvey CK, Gadi R, Nijjar PS, Usman HM, Mehta
NN, Shah R, Master SR, Propert KJ, Reilly MP. Race and gender variation in
response to evoked inflammation. J Transl Med 11(1):63, Mar 2013. Epub ahead.
59. Ferguson JF, Matthews GJ, Townsend RR, Raj DS, Kanetsky PA, Budoff M, Fischer
MJ, Rosas SE, Kanthety R, Rahman M, Master SR, Qasim A, Li M, Mehta NN,
Shen H, Mitchell BD, O’Connell JR, Shuldiner AR, Ho WK, Young R, Rasheed
A, Danesh J, He J, Kusek JW, Ojo AO, Flack J, Go AS, Gadegbeku CA, Wright
JT, Saleheen D, Feldman HI, Rader DJ, Foulkes AS, Reilly MP. Candidate Gene
Association Study of Coronary Artery Calcification in Chronic Kidney Disease:
Findings from the Chronic Renal Insufficiency Cohort Study. J Am Coll Cardiol.
S0735-1097(13)02075-5, May 2013.
60. Blomberg BA, Akers SR, Saboury B, Mehta NN, Cheng G, Torigian DA, Lim E, Del
Bello C, Werner TJ, Alavi A. Delayed time-point 18F-FDG PET CT imaging
enhances assessment of atherosclerotic plaque inflammation. Nucl Med Commun.
June 24, 2013 [Epub ahead of print].
61. Mulvey CK, McNeill AM, Girman CJ, Churchill TW, Terembula K, Ferguson JF,
Shah R, Mehta NN, Qasim AN, Rickels MR, Reilly MP. Differential Associations
of Oral Glucose Tolerance Test-Derived Measures of Insulin Sensitivity and
Pancreatic Beta-Cell Function with Coronary Artery Calcification and
Microalbuminuria in Type 2 Diabetes. Diabetes Care. 2013 Aug 15. [Epub ahead
of print]
62. Mehta NN, Li K, Szapary P, Krueger J, Brodmerkel C. Modulation of
cardiometabolic pathways in skin and serum from patients with psoriasis. J Transl
Med. 2013 Aug 22;11(1):194. [Epub ahead of print]
63. Rose S, Sheth N, Baker J, Ogdie A, Raper A, Saboury B, Werner TJ, Thomas P,
Vanvoorhees A, Alavi A, Torigian D, Gelfand J, Mehta NN. A comparison of
vascular inflammation in psoriasis, rheumatoid arthritis, and healthy subjects by
FDG-PET/CT: a pilot study. Am J Cardiovasc. 2013 [Epub ahead of print]
64.Yueng H, Takeshita J, Mehta NN, Kimmel SE, Ogdie A, Margolis DJ, Shin DB, Attor
R, Troxel AB, Gelfand JM. Psoriasis severity and the prevalence of major
medical comorbity: a population-based study. JAMA Dermatol. 2013.
65. Ferguson JF, Mulvey CK, Patel PN, Shah RY, Doveikis J, Zhang W, Tabita-Martinez
J, Terembula K, Eiden M, Koulman A, Griffin JL, Mehta NN, Shah R, Propert
KJ, Song WL, Reilly MP. Mol Nutr Food Res. 2013 Nov 5.
66. Mehta NN, Matthews GJ, Krishnamoorthy P, Shah R, McLaughlin C, Patel P, Budoff
M, Chen J, Wolman M, Go A, He J, Kanetsky PA, Master SR, Rader DJ, Raj D,
Gadegbeku CA, Shah R, Shreiber M, Fischer MJ, Townsend RR, Kusek J,
Nehal N. Mehta, MD, MSCE, FAHA Page 20
Feldman HI, Foulkes AS, Reilly MP; the Chronic Renal Insufficiency Cohort
(CRIC) Study Investigators. Higher plasma CXCL12 levels predict incident
myocardial infarction and death in chronic kidney disease: findings from the
Chronic Renal Insufficiency Cohort study. Eur Heart J. 2013 Dec 4.
67. Li RC, Krishnamoorthy P, DerOhannessian S, Doveikis J, Wilcox M, Thomas P,
Rader DJ, Reilly MP, Van Voorhees A, Gelfand JM, Mehta NN. Psoriasis is
associated with decreased plasma adiponectin levels independently of
cardiometabolic risk factors. Clin. Exp. Dematol. 2014 vol. 39(1) pp. 19-24.
68. Dave J, Ahlman M, Lockshin B, Mehta NN. Vascular inflammation in psoriasis
localizes to the arterial wall using a novel imaging technique. JAAD. E-pub
ahead.
69. Roe A, Hillman J, Butts S, Smith M, Rader D, Playford M, Mehta NN, Dokras A.
Decreased cholesterol efflux capacity and atherogenic lipid profile in young
women with PCOS. J. Clin. Endocrinol. Metab., 2014.
70. Mehta NN, Gelfand JM. High-density lipoprotein cholesterol function improves after
successful treatment of psoriasis: a step forward in the right direction. J. Invest.
Dermatol., 2014. Vol. 134(3) pp. 592-5.
71. Ferguson JF, Mulvey CK, Patel PN, Shah RY, Doveikis J, Zhang W, Tabita-Martinez
J, Terembula K, Eiden M, Koulman A, Griffin JL, Mehta NN, Shah R, Propert
KJ, Song WL, Reilly MP. Omega-3 PUFA supplementation and the response to
evoked endotoxemia in healthy volunteers. Mol. Nutr. Food. Res. 2014. Mar,
58(3) 601-3.
72. Dominic EA, Ramezani A, Anker SD, Verma M, Mehta N, Rao M. Mitochondrial
cytopathies and cardiovascular disease. Heart. 2014 Jan 21.
73. Takeshita J, Mohler ER, Krishnamoorthy P, Moore J, Rogers WT, Zhang L, Gelfand
JM, Mehta NN. Endothelial cell-, platelet-, and monocyte/macrophage-derived
microparticles are elevated in psoriasis beyond cardiometabolic risk factors. J Am
Heart Assoc. 2014 Feb 28; 3(1).
74. Mehta N, Qamar A, Qu L, Qasim AN, Mehta NN, Reilly MP, Rader DJ. Differential
association of plasma angiopoitin-like proteins 3 and 4 with lipid and metabolic
traits. Arterioscler Thromb Vasc Biol. 2014 May; 34(5).
75. Mehta NN, Dagur PK, Rose SM, Naik HB, Stansky E, Doveikis J, Biancotto A,
Playford MP, McCoy JP Jr. IL-17A production in human psoriatic blood and
Nehal N. Mehta, MD, MSCE, FAHA Page 21
lesions by CD146+ T cells. J Invest Dermatol. 2014 July 24.
76. Subramanain S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG,
Cheng S, Wang TJ, Mehta NN, Levy D. Stromal cell-derived factor 1 as a
biomarker of heart failure and mortality risk. Arterioscler Thromb Vasc Biol.
2014 Jul 24.
77. Rose S, Dave’ J, Millo C, Naik HB, Siegel EL, Mehta NN. Psoriatic arthritis and
sacroiliitis are associated with increased vascular inflammation by
18fluorodeoxyglucose positron emission tomography computed tomography:
baseline report from the Psoriasis Atherosclerosis and Cardiometabolic Disease
Initiative. Arthritis Res Ther. 2014 Jul 30; 16(4):R161 [Epub ahead of print].
Research Publications, peer-reviewed reviews:
1. Mehta NN, Reilly M: Atherosclerotic cardiovascular disease risk in the HAART-
treated HIV-1 population. HIV clinical trials 6(1): 5-24, Jan-Feb 2005. PMCID:
PMC2218847
2. Mehta NN, and Reilly MP.: Mechanisms and Components of the Metabolic
Syndromes. Drug Discovery Today: Disease Mechanisms. 1(1): 1-16, Mar 2005.
3. Shah A, Mehta NN, Reilly MP: Adipose inflammation, insulin resistance, and
cardiovascular disease. JPEN. Journal of parenteral and enteral nutrition 32(6):
638-44, Nov-Dec 2008. PMCID: PMC2712798
4. Gelfand JM, Azfar RS, Mehta NN: Psoriasis and cardiovascular risk: strength in
numbers. The Journal of investigative dermatology 130(4): 919-22, Apr 2010.
PMCID: PMC2866113
5. Farouk SS, Rader DJ, Reilly MP, Mehta NN: CXCL12: a new player in coronary
disease identified through human genetics. Trends in cardiovascular medicine
20(6): 204-9, Aug 2010. PMCID: PMC3235407
6. Gelfand JM, Mehta NN, Langan SM: Psoriasis and Cardiovascular Risk: Strength in
Numbers, Part II. The Journal of investigative dermatology 131(5): 1007-10, May
2011. PMCID: PMC3292325
7. Mehta NN: Large-scale association analysis identifies 13 new susceptibility Loci for
coronary artery disease. Circulation. Cardiovascular genetics 4(3): 327-9, Jun
2011. PMCID: PMC3125595
8. Mehta NN, Rader DJ: Fluorescent green plaques: light at the end of the catheter? Cell
metabolism 14(1): 7-8, Jul 2011. PMCID: PMC3138117
Nehal N. Mehta, MD, MSCE, FAHA Page 22
9. Mehta NN: A genome-wide association study in europeans and South asians identifies
5 new Loci for coronary artery disease. Circulation. Cardiovascular genetics 4(4):
465-6, Aug 2011. PMCID: PMC3190399
10. Mehta NN: Large-scale gene-centric analysis identifies novel variants for coronary
artery disease. PLoS genetics 7(9): e1002260, Sep 2011. PMCID: PMC3178591
11. Mehta, NN.: A GWAS of South Asians and Europeans Detects Five Novel CAD
Loci. Circulation. Cardiovascular Genetics in press: accepted 7/6/11, September
2011.
12. Farouk S, Rader DJ, Reilly MP, Mehta NN: CXCL12: A New Player in Coronary
Disease Identified through Human Genetics Trends in Cardiovascular Medicine
2011 Notes: in press.
13. Mehta NN: The effect of chromosome 9p21 variants on cardiovascular disease may
be modified by dietary intake. Circulation. Cardiovascular genetics 5(1): 148-50,
2012 Feb 1. PMCID: PMC3285416
14. Mehta NN, Reilly Muredach P: Monocyte mayhem: do subtypes modulate distinct
atherosclerosis phenotypes? Circulation. Cardiovascular genetics 5(1): 7-9, 2012
Feb 1. PMCID: PMC3285416
Research Publications, non-peer reviewed:
1. Mehta, NN.: Novel Risk Factors and Primary Prevention of Coronary Artery Disease.
Hospital Physician Page: 1-9, Aug 2006.
Abstracts:
1. Mehta, NN, Schutta, M, Wolfe, ML, Iqbal, N, Kimmel, SE, Rader, DJ, Reilly, MP:
Plasma adiponectin levels, cardiovascular risk factors, and coronary
atherosclerosis in type 2 diabetes. Arteriosclerosis Thrombosis And Vascular
Biology 24(5): P243, May 2004.
2. Reilly MP, Wolfe M, Rhodes T, Girman C, Mehta NN, Rader DJ.: Measures of Insulin
Resistance Add Incremental Value to the NCEP Metabolic Syndrome Criteria in
the Association with Coronary Artery Calcification. Circulation 110(7), Aug
2004.
3. Anderson, PD, Mehta, NN, Wolfe, ML, McMahon, K, Hinkle, C, Comiskey, L,
Tabita-Martinez, J, Sellers, K, Ahima, BS, Rader, DJ, Reilly, MP: Adipokines
in human endotoxemia. Journal Of Investigative Medicine 53(2): S388, Mar
2005.
Nehal N. Mehta, MD, MSCE, FAHA Page 23
4. Mehta, NN, Anderson, PD, Wolfe, M, Rickels, M, Zemel, B, Hinkle, C, Comiskey,
L, Tabita-Martinez, J, Ahima, R, Rader, DJ, Reilly, MP: Adiposity and pro-
atherosclerotic responses to innate immune challenge in humans. Journal Of
Investigative Medicine 53(2): S391, Mar 2005.
5. Anderson, P, Mehta, NN, Wolfe, ML, Hinkle, CC, Tabita-Martinez, JJ, Sellers, KF,
Rader, DJ, Reilly, MP: Atherogenic changes in apo-B lipoproteins during human
inflammation. Circulation 112(17 Suppl. S): 1215 Oct 2005.
6. Anderson, PD, Mehta, NN, Wolfe, ML, McMahon, KE, Hinkle, CC, Comiskey, L,
Tabita-Martinez, JJ, Sellers, KF, Ahima, RS, Rader, DJ, Reilly, MP:
Pathophysiology of insulin resistance in human inflammation. Circulation 112(17
Suppl. S): 3821, Oct 2005.
7. Anderson, P.A., Mehta, N., wolfe, M.L., McMahon, K., Hinkle, C., Comiskey, L.,
Tanbita-Marinez, J., Sellers, K., Ahima, R. S., Rader, D.J., Reilly, M.P.:
Pathophysiology of insulin resistance in human inflammations. Circulation
112(II): 827, 2005.
8. Mehta, NN, Anderson, P, Wolfe, M, Rickels, M, Zemel, B, Hinkle, C, Tabita-
Martinez, J, Ahima, R, Sellers, K, Rader, DJ, Reilly, MP: Adiposity and
atherogenic inflammatory response to endotoxin in humans. Journal Of The
American College Of Cardiology 47(4 Suppl. A): 308A, Feb 2006.
9. Mehta, NN, Anderson, PD, Hinkle, C, Tabita-Martinez, J, Rickels, MR, Reilly, MP:
Modulation of the insulin signaling pathway in human inflammation.
Arteriosclerosis Thrombosis And Vascular Biology 26(5): E49, May 2006.
10. Mehta, Nehal N, Mohler, Emile R, III, Amrutia, Shirsh, Reilly, Muredach P:
Abstract 3923: The Effect of Selective PKC-Inhibitor Ruboxistaurin on
Endothelial Function and Oxidant Stress in Patients with Type 2 Diabetes
Mellitus. Circulation 114: II_843-c- 2006.
11. de la Llera-Moya, Margarita, Pruscino, Leticia, Wolfe, Megan L, Nguyen, Vihn,
Mehta, Nehal, Reilly, Muredach P: Abstract 670: Serum Amyloid A May
Attenuate the Loss of HDL Efflux Capacity During Human Endotoxemia.
Circulation 114: II_112-b- 2006.
12. Heffron, SP, Mehta, NN, de la Llera-Moya, M, Pruscino, L, Tabita-Martinez, J,
Wolfe, M, Badelino, K, Rader, DJ, Reilly, MP: Degree of acute phase response
predicts extent of HDL remodeling in human inflammation. Arteriosclerosis
Thrombosis And Vascular Biology 27(6): E68, Jun 2007.
Nehal N. Mehta, MD, MSCE, FAHA Page 24
13. Heffron, SP, Mehta, NN, de la Llera-Moya, M, Terembula, K, Hinkle, C, Wolfe,
M, Reilly, MP: Abstract 1097: Very-low Dose Endotoxemia Induces High
Density Lipoprotein Remodeling and Reduces Cholesterol Efflux in the Absence
of a Clinical Inflammatory Response. Circulation 116: II_220-a- 2007.
14. Mehta, NN, Heffron, SP, Rickels, MR, Terembula, K, Ginwala, NT, Hinkle, C,
Wolfe, ML, Rader, DJ, Reilly, MP: Abstract 3593: Very-low Dose Endotoxemia
Induces Insulin Resistance in the Absence of Clinical Inflammatory Responses.
Circulation 116: II_814- 2007.
15. Varanasi, A, Mehta, NN, Hinkle, C, Udupa, J, Ginwala, NT, Reilly, MP:
Relationship between visceral adiposity, inflammatory markers, and insulin
resistance following human endotoxemia. Arteriosclerosis Thrombosis And
Vascular Biology 28(6): P507, Jun 2008.
16. Qasim, AN, Martin, SS, Mehta, NN, Rader, D, Reilly, MP: Abstract 3210: Lp(a) is
Strongly Associated with Coronary Artery Calcification in Type 2 Diabetic
Women. Circulation 118: S_1113-c- 2008.
17. Mehta NN, William D, Khera A, Edmondson , Qasim A, Restine S, Pruscino L,
Hinkle C, He J, Stylianou I, Li M, Rader DJ, Reilly MP: A Novel GWAS
Atherosclerosis Locus Regulates Plasma Levels of CXCL12. Gordon Conference
Journal June 2009.
18. Mehta NN, Li M, Epstein S, Keating B, Hakonarson H, Rader DJ, Reilly MP.: The
ITMAT/Broad/CARE (IBC) Candidate Gene Array Identifies Novel Type 2
Diabetes Gene Associations with Coronary Artery Disease: The GRAND-CAD
Consortium. American Society of Human Genetics Nov 2009 Notes: (presentation
American Society of Human Genetics, 2008).
19. Martin SS, Rader DJ, Mehta NN, Wolfe M, Terembula K, Schwartz S, Iqbal N,
Schutta M, Bagheri R, Reilly MP, Qasim AN: Abstract 1618: High-Density
Lipoprotein Cholesterol but Not Apolipoprotein A-I or -II is Associated With
Coronary Calcium in Type 2 Diabetes. Circulation 120(18_MeetingAbstracts):
S531- 2009.
20. Mehta, NN, Azfar, RS, Shin, DB, Neimann, AL, Troxel, AB, Gelfand, JM:
Abstract 1640: Patients With Severe Psoriasis and No History of Cardiovascular
Disease Are at Increased Risk of Cardiovascular Mortality. Circulation 120:
S536-b- 2009.
21. Mehta, NN, William, D, Pruscino, L, Khera, A, Edmondson, A, Qasim, A,
Restine, S, Hinkle, C, He, J, Stylianou, I, Li, M, Rader, DJ, Reilly, MP:
Abstract 2077: A Novel GWAS Atherosclerosis Locus Regulates Plasma Levels
of CXCL12. Circulation 120: S589-a- 2009.
Nehal N. Mehta, MD, MSCE, FAHA Page 25
22. Varanasi, A, Bose, S, Udupa, J, Duglash, R, Chandrupatla, H, Iqbal, N, Schutta,
M, Reilly, MP, Mehta, NN: Abstract 1623: Quantification of Visceral Adipose
Tissue Adds Value to BMI and Metabolic Syndrome in Prediction of Subclinical
Atherosclerosis in Men With Type 2 Diabetes. Circulation 120: S532- 2009.
23. Ferguson J, William D, Wang X, Qu L, Mehta NN, Reilly MP: Genetic variation in
CRP and PLA2G7 has differential associations with subclinical coronary
atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology Annual
Conference 2010.
24. Eraso LH, Ferguson J, Mehta NN, Li M, Keating B, Mohler III ER, Reilly MP:
Candidate Gene Association Study of Peripheral Arterial Disease in Type 2
Diabetes. Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference
2010.
25. Mehta, NN, Reilly, M, Rader, D, Mohler, E, VanVoorhees, A, Gelfand, J: Abstract
P040: Advanced cardiometabolic phenotyping in psoriasis links between psoriasis
and cardiovascular disease? 3rd
World Psoriasis & Psoriatic Arthritis Conference
2012.
26. Mehta NN, Matthews G, Budoff M, Chen J, Glenn M, Go A, He J, Kanetsky P,
Master S, Rader DJ, Raj D, Shah R, Screiber M, Fischer M, Townsend R, Kusek
J, Feldman H, Foulkes A, Reilly MP: Higher Plasma CXCL12 Levels Predict
Incident Cardiovascular Disease Events: Findings from the Chronic Renal
Insufficiency Cohort Study. American Heart Association Scientific Sessions
2012.
27. Sheth N, Baker J, Ogdie A, Roper A, Saboury B, Werner T, Thomas P, Van
Voorhees A, Alavi A, Torigian D, Gelfand J, Mehta NN: A Comparison of
Vascular Inflammation in Rheumatoid Arthritis, Psoriasis and Healthy Controls
by FDG-PET/CT: A pilot Study. American College of Cardiology Annual
Meeting 2013.
28. Mehta NN, Dagur PK, Stansky S, Rose S, Biancotto A, Sonti K, Playford M, McCoy
J.P.: CD146 expression identifies Th17 and Tc17 subsets in psoriatic blood and
skin. International Investigative Dermatology Conference 2013.
29. Rose S, Sonti K, Dagur P, Lee P, Playford M, Celi F, Mehta NN: Characterization of
adipose tissue inflammation may link psoriasis and cardiometabolic disease.
International Investigative Dermatology Conference 2013.
30. Sheth, NH, Baker J, Ogdie A, Roper A, Saboury B, Van Voorhees A, Alavi A,
Torigian D, Gelfand J, Mehta NN: The Use of FDG-PET/CT to Evaluate Vascular
Inflammation in Inflammatory Diseases Compared to Healthy Controls: A Pilot
Study. SNMMI Annual Meeting 2013.
Nehal N. Mehta, MD, MSCE, FAHA Page 26
31. Takeshita J, Saboury B, Salavati A, Torigian DA, Van Voorhees A, Mehta NN,
Alavi A, Gelfand JM: 18-Fluorodeoxyglucose Positron Emission Tomography-
Computed Tomography (FDG PET-CT) as a Novel Tool for Quantification of
Psoriasis Disease Activity: Proof of Concept from the Vascular Inflammation in
Psoriais (VIP) Trial. Journal of Investigative Dermatology. 133(1): S177, May
2013.
32. Krishnamoorthy P, Rader DJ, Reilly M, Mehta NN: Advanced Lipid Testing Predicts
Subclinical Atherosclerosis in Low Risk Population Beyond Traditional Risk
Factors. International Academy of Cardiology 2013.
33. Griffiths C, Reich K, Leonardi C, Blauvelt A, Mehta NN, Tsai T-F, Gong Y, Huang
J, Fox: Secukinumab Demonstrates an Acceptable Safety Profile in Moderate to
Severe Plaque Psoriasis: Pooled Analysis of 10 Phase 2/3 Studies. European
Academy of Dermatology and Venereology Congress 2014 Late Breaking
Abstract.
Books:
1. Christopher P. Cannon, MD and Nehal N. Mehta, MD, FACP: Contemporary
Guide to Cardiovascular Therapy. (First Edition), July 2008 Notes: ISBN
9781931981880.
2. Stephen Pan, MD, MS, Juyong Brian Kim, MD, MPH, Nehal N. Mehta, MD,
MSCE, FAHA, Joshua W. Knowles, MD, PhD, FAHA, FACC: “Genetic
Applications in Coronary Artery Disease,” in Cardiovascular Genetics and
Genomics in Clinical Practice. 2014.