Cancer complexity from genetic to clinical levels
Basic issues in medical oncology
• Comprehensive evaluation at diagnostic and recurrences (chronic disease)
• Multidisciplinary care
• Patient pre-habilitation and re-habilitation prior to cancer therapy
• The constant progresses, the complexity of multidisciplinary medical care and long term follow up required for each cancer patient require continuous training for medical and paramedical professional
Saint-Joseph oncology background
• Organize quick and comprehensive workup to speed up patient care
• Take any decision for individual in a multidisciplinary manner, based on documented medical evidences
• Understand patient needs (nutrition, physical activities, psychological issues) to prepare for anticancer treatment appropriately
• Ensure continuous medical and paramedical trainings
Medical expertise: Type of tumors
• Thoracic oncology
• Breast cancer
• Gynecological cancer (GYN)• Uterine (cervix and corpus) • Ovarian carcinoma
• GI tumor (GI)• Colorectal cancer• Esophageal cancer• Gastric cancer• Anal margin• Pancreatic cancer• Primary liver tumors
• Hepatocellular carcinoma• Cholangiocarcinoma
• Urinary track cancers (GU)• Prostate adenocarcinoma• Bladder cancer• Kidney cancer• Testicular cancer
• Head and neck tumors• Squamous cell• Adenocarcinoma
• Rare tumor types• Neuroendocrine tumors• Sarcomas• Skin cancer (Melanoma and squamous)• Brain tumors• Carcinoma of unknown primary
• Lymphomas
Multidisciplinary evaluations and decisions
Imaging diagnostic
PathologyInterventional
radiology
Multidisciplinary decisions for therapySurgery
Radiotherapy
Interventional radiology
Chemotherapy
Targeted therapy
Immunotherapy
Radionuclide therapies
Clinical and translational cancer options
Rehabilitation and pre-habilitation therapy
Palliative care and pain therapy
Imaging (CT, MRI, PET)
Pathology
Molecular biology
Genetic counseling
Individualizedtreatment decision
& strategy
Surgery
• Pre-habilitation to optimize patient recovery and outcome
• Outpatient surgery
• Robotic surgery
• PIPAC : Pressurized Intraperitoneal Aerosol Chemotherapy
Interventional radiology
• Transcutaneous radiofrequency
• Chemoembolization
• Intra-arterial chemotherapy
• Per-operative radiofrequency and cryotherapy ablation
Medical oncology
• Chemotherapy
• Targeted therapy• Anti-oncogenic agents
• Antiangiogenic agents
• Immunotherapy• Checkpoint inhibitors
• Vaccination
Combined strategies
Combine multiple approaches to optimize the overall survival benefit and quality of life of patients
Clinical & Translational Cancer Research
• National and international networking for cancer research• France (INCa, FFCD, GERCOR, GETUG)
• European• EORTC (www.eortc.org)
• OncDistinct
• PAMM
• ENETS
• International• WIN (ASCO)
• AACR (ENA)
International patients
• Quick evaluation of treatment options (<3 days)
• Medical advise or proposal for care in Saint-Joseph
• Fair quotations of patient care
Medical and paramedical training
• Physicians in medical and scientific training (theoretical adn at patient bedside)
• MD and PhD formation
• Medical oncology specialization
• Paramedical formation
Areas of potential collaborations
• Medical and paramedical training
• Medical expertise
• Data mining
• Translational and Clinical Research
• Hospitality for selected cases requiring care in France
Conclusion
• Comprehensive multidisciplinary cancer care at Saint-Joseph Hospital to match medical needs
• Potential for collaborations in welcoming physicians in training for doctoral and post-doctoral positions (MD, PhD) for medicine and/or research
• Potential for collaboration for paramedical formation
• Interest for networking in clinical and translationalresearch
Thanks for your attention