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MRI showing plaque of multiple sclerosis.
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Left: Coronal section of cerebrum showing multiple sclerosisPlaques at the apex of both lateral ventricles.Right: HE/LFB stain of axial section of pons showing severalMultiple sclerosis plaques.
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Left: Sharp edge of demyelination in MS plaque. Right: Macrophage infiltrate and astrogliosis in MS plaque.
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Axial section of pons and cerebellum showing discolorationAnd softening of central pontine myelinolysis.
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Axial whole-mount section of cerebrum stained with LFBShowing caudal-to-rostral gradient of demyelination in adrenoleukodystrophy.
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Loss of myelin and perivascular inflammatory infiltrate in affectedRegion of white matter in adrenoleukodystrophy (HE stain).
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Cerebral white matter showing Globoid cells of Krabbe’s disease (HE stain).
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Subpial collection of Rosenthal fibers in a cerebral gyrus from an infant who died of Alexander’s disease.