Transcript

https://master-neuroscience-paris.fr

[email protected]

MASTER’SPROGRAMINNEUROSCIENCE

SecondyearM2

Listofmodulesataglance

Coursesare taught inEnglish. In addition to coremodules (15ECTS), each studenthas tovalidate 6 ECTS in cellular and molecular neuroscience, and 6 ECTS in integrativeneuroscience.Optionalmodulesareofferedineachspecialization.

Specific optional modules (3 ECTS) from other Master’s programs are also offered (seebelow).KeepinmindthatthetimetablecompatibilitybetweendifferentMaster’sprogramsandthenumberofplacesavailablepermodulearesubjecttochangeeachacademicyear.

S3:Semester3;S4:Semester4;ECTS:EuropeanCreditTransferandAccumulationSystem

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:Researchproposal

Course(s)supervisor(s):

Title:Prof.UniversitédeParisFirstname:Mehrnaz LASTNAME:JAFARIAN-TEHRANITitle:MCUUniversitédeParis Firstname:Isabelle LASTNAME:CAILLE

Totalnumberofhours:fewpracticalsessions,mainlypersonalandteamworking

NumberofECTS:3

Semester:Semester3(M2)☒

Description:Tobeabletowriteanddefendaresearchproposalover3yearsbasedonascientificpublication,and fictive collaborations through interactions with the scientific community, researchers and engineers inresearchlabsortechnicalfacilities.ThestudenthastowriteaproposalaccordingtotheinstructionsgivenatthebeginningofthesemesterandfinallybeabletodefendtheproposalinfrontofaJury.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Mandatorycourse☒

Prerequisites/skillsneeded:M1Neuroscience(UEMethodologiesinNeuroscienceS1andS2)

Keywords:Researchproject;experimentaldesign;scientificreport;scientificcollaboration

Teaching methods and activities: personal/team working (to be proactive and interactive withresearchers/engineers)

Assessment:writtenreportanddefense

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:Neuroimaging

Course(s)supervisor(s):

Title:MCUUniversitédeParis Firstname:Clément LASTNAME:RICARDTotalnumberofhours:24h

NumberofECTS:3

Semester:Semester3(M2)☒

Description:Giveanoverviewofthedifferentneuroimagingtechniquesandapproachesfromtheresearcher,clinicianandindustrialpointofview.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Mandatorycourse☒

Prerequisites/skillsneeded:Knowledgeinneuroanatomy(attendingtheM1«Neuroanatomiefonctionnelle»courseisnotmandatorybutrecommended).

Keywords:Neuroimaging,Optics,MRI,CT-Scan,Ultrasound,Nuclearimaging

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:DrugDiscoveryforNervoussystem

Course(s)supervisor(s):

Title:CRCNRS Firstname:NicolasLASTNAME:MARIETitle:Prof.UniversitédeParisFirstname:Charbel LASTNAME:MASSAADTotalnumberofhours:24h

NumberofECTS:3

Semester:Semester3(M2)☒

Description: Neuropharmacology is the study and understanding of the actions of chemical agents onneurobiologicalprocessesinnervoussystem.Studentswilldiscovertherecentadvancesinneuropharmacologyandsomeaspectsofthedevelopmentofdrugsforthenervoussystemregardingmedicalspecialties.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Mandatorycourse☒

Prerequisites/skillsneeded:Strongbackgroundinphysiologyandneuropharmacology

Keywords:Optopharmacology,drugdevelopment,biasedligands,drugdelivery

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:Nervoussystemdisordersandrepair

Course(s)supervisor(s):

Title:Prof.UniversitédeParisFirstname:Mehrnaz LASTNAME:JAFARIAN-TEHRANITotalnumberofhours:48h

NumberofECTS:6

Semester:Semester3(M2)☒

Description: Recent advances in the pathophysiology of nervous system (CNS and PNS) disorders includingneurodegenerativediseases,psychiatricdisorders,movementdisorders,pathologiesofmyelin,braininjuryandcerebrovascular diseases, neurotropic viral infection, neuro-oncology and neuropathy. Some aspects ofnervous system repair are taught related to stem cell therapy, neuroprotection, physical exercise and brainstimulation.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Mandatorycourse☒

Prerequisites/skillsneeded:Neurobiology,neuroanatomy

Keywords:CNS and PNS disorders, Psychiatric disorders, Parkinson, Alzheimer, Huntington, Prion diseases,cerebrovasculardiseases, stroke,brain injury,multiple sclerosis,movementdisordersALS, SMA,Neurotropicviralinfections,Neuro-oncology

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:BrainPlasticity

Course(s)supervisor(s):Title:MCUUniversitédeParis Firstname:Isabelle LASTNAME:CAILLETitle:DRINSERMFirstname:Thierry LASTNAME:GALLITotalnumberofhours:24h

NumberofECTS:3

Semester:Semester3(M2)☒

Description:Neuralplasticity is thecapacityof thenervoussystemtoconstantlymodify itself throughoutanindividual'slife.Theaimofthisclasswillbetounderstandhowbehavioralexperiencesandneuralactivitycanmodify the structure and function of neural circuits. We will also consider how age and diseases candifferentiallyaffecttheseprocesses.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Optionalcourse☒

Prerequisites/skillsneeded:Knowledgeincellularandmolecularneurobiology

Keywords:structuralplasticity,synapticplasticity(LTP,LTD),GenomicPlasticity,synapticpruning,autophagy,criticalperiods,learningandmemory,adultneurogenesis,maladaptiveplasticityinbraindisordersandageing,glialplasticity

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:Epigenetic,developmentandbrainintegrity

Course(s)supervisor(s):Title:DRCNRS Firstname:Valérie LASTNAME:MEZGERTitle:MCUUniversitédeParis Firstname:Délara LASTNAME:SABERAN-DJONEIDITitle:MCUUniversitédeParisFirstname:Véronique LASTNAME:DUBREUILTotalnumberofhours:24h

NumberofECTS:3

Semester:Semester3(M2)☒

Description:Thecourseaimsatprovidingin-depthresearch-basedknowledgeabouttheepigeneticprocessesthat govern behaviors and brain functions. The student will appreciate how basic epigenetic mechanismstightlyregulatebraindevelopment,neuralcelldifferentiationandbrainintegrity,andhowtheperturbationofnormalepigeneticprocessesleadtoawidespectrumofneurodevelopmentalandneuropsychiatricdisorders.Moreover,specialfocuswillbeputontheimpactofenvironmentalinsultsontheneuralepigenomeandneuralcellfateduringdevelopmentandinalifetimemanner,totheprotectiveresponses,whichunderliestheproperbrainfunctions.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Optionalcourse☒(maximum16students)

Prerequisites/skillsneeded:braindevelopment,molecularandcellularbiology

Keywords:Epigenome,neurodevelopment,brainintegrity,NGS,cohortanalysis,neurodegenerescence

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:Glialandnon-neuronalcellbiology

Course(s)supervisor(s):Title:Prof.UniversitédeParis Firstname:Charbel LASTNAME:MASSAADTitle:Prof.UniversitédeParisFirstname:Mehrnaz LASTNAME:JAFARIAN-TEHRANITotalnumberofhours:24h

NumberofECTS:3

Semester:Semester3(M2)☒

Description:Theaimofthisteachingunitistolearntherecentadvancesinglialbiologyandglialandnon-glialcell interactions.Besides themain courses, tutorialswill guide the students toperform innovative academicprojectbasedonthetopicsdevelopedduringthemainlectures.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Optionalcourse☒

Prerequisites/skillsneeded:cellularandmolecularneurobiology,electrophysiology

Key words: schwann cell, astrocyte, oligodendrocyte, microglia, endothelial cell, neurovascular unit, cellinteraction,neuron-gliainteraction

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:RNAregulationintheCNS

Course(s)supervisor(s):

Title:MCUUniversitédeParis Firstname:Laure LASTNAME:WEILLTotalnumberofhours:24h

NumberofECTS:3

Semester:Semester3(M2)☒

Description:Thecourseprovidesanin-depthknowledgeonRNAmetabolismandRNAregulationanditsroleinneurobiology: brain development and cell differentiation, plasticity and how RNA deregulation can lead todifferentneuropathology.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Optionalcourse☒

Prerequisites/skillsneeded:MolecularBiology

Key words: Ribonucleopathy (splicing disease), RNA localization, local translation, non coding RNA, mRNAbodies

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:SystemsandintegrativeNeuroscience

Course(s)supervisor(s):Title:CRCNRS Firstname:Mathieu LASTNAME:BERANECKTotalnumberofhours:24h

NumberofECTS:3

Semester:Semester3(M2)☒

Description: thegoalof theSystemsand IntegrativeNeuroscience course is toprovide thestudent thebasicknowledgeregardingthemethodologiesandapproachesusedtostudyfunctionalneuralsystems.Thecoursebringstogetherteachersandresearcherswhoarestudyingdifferentfunctionsonvariousspecies.Theyallworktounderstandhowfunctionsemergebystudyingtheir respectivesystemsatdifferent levelswithaso-calledintegrativeapproach.Foreach systemwewill consider the roleof theelectrophysiologicalpropertiesof theneurons,ofthepropertiesthatemergefromneuralnetworksandmicrocircuits,andrelatethesepropertiestoquantifiedbehavioursthroughmodeling.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Optionalcourse☒

Prerequisites/skillsneeded:Master1inNeuroscience;basicknowledgeregardingsensoryandmotorsystems;basicknowledgeaboutcellularelectrophysiology

Keywords:multisensory integration; sensory systems;motor systems; sensorimotor; balance; orientation&navigation;basalganglia-thalamus-corticalloop;cerebellum;oculomotorsystems;electrophysiologicalintrinsicproperties and synaptic properties; microcirtuits; models of action selection; models of learning; statisticalmodels;principleofmaximumlikelihood;baysianmodels;initialtheories;memory&learning;Hebbtheoryandexperimentaldemonstrations

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:Neurogenetics,psychiatryandbehavior

Course(s)supervisor(s):Title:CRINSERM Firstname:Nicolas LASTNAME:RAMOSTotalnumberofhours:24h

NumberofECTS:3

Semester:Semester3(M2)☒

Description: This course aims to explain the interface between basic research in neuroscience, throughdifferent strategies, especiallymolecular biology of genetics, epigenetics and pharmacogenetics, and clinicalresearchtounderstandbehaviorandpsychiatricdisorders.Italsoaimstopresentclinicalresearchinordertoshowitscontributiontotheunderstandingofpsychiatricdiseasesandtheinterestofdevelopingtranslationalresearch.Intheend,thiscourseaimstoshowbypracticalexamplestheinterestofneuropsychiatricdomainsintheunderstandingofnormalandpathologicalbehaviors.

Exact location:CampusSaint-GermaindesPrés, FacultyofBasicandBiomedicalSciences,45 ruedesSaints-Pères,75006Paris

Optionalcourse☒

Prerequisites/skillsneeded:M1insciencewithagoodunderstanding infundamentalneuroscience,geneticsormolecularbiologyorM1inhealthwiththemedicalpracticeinneuroscience,psychiatryorpharmacology.

Key words: addiction, brain molecular biology, Epigenetics, Genetics, human behavior,psychopharmacogenetics,translationalpsychiatry

Teachingmethodsandactivities:lectures(CM)☒Practicalsessions(TD)☒

Assessment:continuousassessmentandexam

https://master-neuroscience-paris.fr

[email protected]

MASTERNEUROM2

COURSEOUTLINE

CourseTitle:InternshipprojectandResearchInternship

Course(s)supervisor(s):Title:Prof.UniversitédeParisFirstname:Mehrnaz LASTNAME:JAFARIAN-TEHRANITitle:MCUUniversitédeParis Firstname:Isabelle LASTNAME:CAILLETotalnumberofhours:5to6-monthinternship

NumberofECTS:6ECTS(Internshipproject)+24ECTS(Researchinternship)

Semester:Semester4(M2)☒

Description:Anoverall five to six-month internship is required to validate theM2 level. Before starting theinternship,studentshavetopresentanddefendtheirinternshipproject(6ECTS)atthebeginningofsemester4.Theyhavetocontacttheir internshipsupervisorduringsemester3andspendtimewiththehostresearchteaminordertounderstandtheirresearchproject.Exactlocation:ResearchteamsinFranceorabroad,butmainlyresearchteamsaffiliatedtotheParisUniversity(seeMasterNeurointernshipoffers).

Mandatorycourse☒

Prerequisites/skillsneeded:MasterNeuroS3

Keywords:Research teams,Europe, International,CNRS, INSERM, IPNP,Neurodiderot,Cochin,Necker,BFA,InstitutImagine,CampusSaint-GermaindesPrés

Teachingmethodsandactivities:Experimentalwork☒attendingtheneuroscienceseminars☒

Assessment:writtenreportanddefense


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