Bio Informatics Research IndiaBio Informatics Research – India
August 2012
Executive Summary
Market
Indian Bioinformatics research market was value at around INR xx bn in 2011 and is expected togrow at a CAGR of 25.4% to reach INR yy bn by the end of 20‐‐
In 2011, the market accounted for a mere zz% of the Indian biotechnology market
A li i
Molecular Medicine
Microbial Genome Application
Percentage of exports during the period of 2010‐11 witnessed an increase of aa percentagepoints to reach bb% from 32% in previous year
Application Areas
Microbial Genome Application
Agriculture
Animal Study
Comparative Studies
Key IT Profiles
IT Vendors
HCL Technologies Wipro Ltd.
Tata Consultancy Services Ltd. Cognizant Technology Solutions India Pvt. Ltd.
CompetitionKey Bio Informatics Players
Biobase Databases India Pvt. Ltd. CLC Bio India Pvt. Ltd.
2BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
GVK Biosciences Pvt. Ltd. Siri Technologies Pvt. Ltd.
•Introduction
•Market Overview
i i f i h l•Bioinformatics Technology
•Application Areas
•Market Influencers•Market Influencers
•Government Initiatives & Framework
•Major Research Institutes•Major Research Institutes
•Key IT Vendor Profiles
•Bioinformatics VendorsBioinformatics Vendors
•Recent Corporate Activities
•Strategic Recommendation
3BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
•Appendix
Indian Biotechnology Industry ‐ Summary
Indian Bio Tech Industry
Bio Pharma Bio Agri Bio Industrial
Bio Services Bio Informatics
Database Services Research Applications Software Services
4BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
SAMPLE Biotechnology industry in India withholds tremendous potential in the years to come
• Indian biotechnology industry is flourishing at an unprecedented growth rate over the years
• Can be segregated into five sectors, i.e. Bio agri, Bio
Market Overview ‐ India Market Forecast ‐ India
INR bng g , g ,
industrial, Bio services, bio pharma and bio informatics
• xxx held a lion’s share of close to 62% of the overall market in 2011
• Karnataka has emerged as the nation’s biotech hub in 0
axx
b
c
the recent years
Bio Technology Industry ‐ India
2012e 2013e 2014e 2015e 2016e
• Increasing demand Increasing population with rising income is primarily aiding
Growth Factors
• Some of the top players in the industry are as follows:
Competition
g p p g p y gthe market
• Favorable support from Government of India Rise in GoI spending and R&D has played a crucial role
• Burgeoning investments Increasing investments from domestic players and the
Biocon
Serum Institute of India
Panacea Biotec
Nuziveedu Seeds
5BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
g p yexisting FDI policy acts in the favor of the market Reliance Life Sciences
The list of cities is not exhaustive
SAMPLE Although comprising of a mere xxx% of the overall biotech industry, bio informatics is fast gaining pace
18 8%e
d
b
a
India Bio‐Tech Industry – Segments (2011)India Bio‐Tech Industry – Size & Growth
INR bn
1.6%3.6%
14.4%18.8%
ca
b
c
d
xyx
61.7%0
201120102009200820072006
INR bn
Bio‐Informatics India – Size & GrowthBio‐Informatics Market Insights ‐ India
%% Share Exports% Share Domestic
a
b
c
aaaa
b
c
d
db
c
a
6BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
0
2016e2015e2014e2013e2012e20112010 2011
0
SAMPLE SWOT Analysis – Bioinformatics India
•Vast talent pool
Strength Weakness•Vast talent pool•Robust IT industry• Improving academic support• Strong network of bioinformatics centre across India
• Lack of high level computation infrastructure R&D centres
• Lack of risk capital venture funds• Lack of integrity at a national level
•Ample government intervention
SWOT
• Establishment of bio tech parks across India
Opportunity
• Emerging competition from tech savvy foreign companies
Threat
• Tax incentives form GoI for bioinformatics
•Growth of domestic bio industries
•Over dependence on IT sector•Complex IP ownership of bioinformatics databases
7BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
SAMPLE Key Bioinformatics Tools (1/x)
• The Basic Local Alignment Search Tool (BLAST) is a tool used to compare genes and protein sequence with the data available in public databases
BLASTp
• Some of the popular variants include PSI‐BLAST, PHI‐BLAST and BLAST 2 sequences
• Special tailor made BLASTs are also available for human, microbial, malaria, and other genomes, as well as for vector contamination immunoglobulin andas for vector contamination, immunoglobulin, and tentative human consensus sequences
•Designed by Lipman and Pearson, the tools is based on rapid sequence algorithm
• It is basically a database searching tool used for theFASTA
It is basically a database searching tool used for the comparison of nucleotide or peptide sequence to a sequence database
• The speed and sensitivity of the search is actually inversely proportional to the size of the word searched
8BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
inversely proportional to the size of the word searched for
SAMPLE Major Application Areas of Bioinformatics ‐ Summary
•Ongoing development in the field of bioinformatics in India has brought forward a plenty of opportunities for vendors in the market
•Currently the market has numerous lucrative segments wherein bioinformatics implication is in full swing• Some of the major application areas can be illustrated as below:Some of the major application areas can be illustrated as below:
Molecular Medicine Microbial Genome Applications AgricultureMolecular Medicine
Drug Tests
Personalised Medicine
Preventive Medicine
Microbial Genome Applications
Waste Cleanup Antibiotic Resistance
Climate Change Forensic Analysis of Microbes
Alternative Energy sources Bio weapon Creation
Agriculture
Crops
Insect Resistance
Improve Nutritional Quality
Gene Therapy gy p
Biotechnology Evolutionary Studies Enhancement in Crop Raising
Animals Comparative StudiesAnimals
Sequencing
Improving Animal Health
Comparative Studies
Analysis of Genetic Material
Research on Species Evolution
9BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
SAMPLE Drivers and Challenges – Bio Informatics Market India
• The industry gets a major boost from the easily available talent pool
• Frequent changes in the regulatory frameworks and compliance to the same
Drivers Challenges
y p With numerous colleges and institutions churning out a vast number of skilled human resource relevant for the market, it is basically attracting outsourced research activity Outsourcing has generated close to 90% of the industry’s
frameworks and compliance to the same proves to be a major hindrance for the market
• Additionally, the constant changes in the technological landscape puts vendors under the pressure of continual upgradation of ITindustry s
revenue in the last • Additionally, labor cost in India is also far less than the markets present abroad
• Increasing healthcare expenditure amongst
the pressure of continual upgradation of IT infrastructure
• Rise in costs associated with R&D activities and the fast drying product line‐up is also a major cause of concern for a majority of• Increasing healthcare expenditure amongst
the Indian population is also a prime factor to propel growth in the industry
• Burgeoning export figures over the years further add to the growth of the market by a
major cause of concern for a majority of players operating in the market
• Interoperability of data is another major hindrance faced by vendors on the technological endfurther add to the growth of the market by a
large extent
• Favorable government initiatives such as the R&D focus and 100% FDI allowance through h i d i h k b
g
• Furthermore the intense competition prevailing in the industry is also forcing players to operate in lower profit margins which again is a major hindrance for the
10BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
the automatic route drive the market by manifolds
is a major hindrance for the market
SAMPLE Regulatory Framework – India Bio Technology Industry
Government of India
Ministry of Science & TechnologyMinistry of Environment &
Forests
Department of BiotechnologyDepartment of Environment,
Forests & WildlifeForests & Wildlife
Recombinant DNA Advisory Committee
(RDAC)
Regulatory Committee on
Genetic Manipulation(RCGM)
Institutional Biosafety Committee
(IBSC)
Genetic Engineering Approval Committee
(GEAC)
11BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
SAMPLE So far GoI has developed an efficient strategy to shape up the bio informatics industry in India
• The strategy and plan chalked out as of now is aimed to provide an all round support towards the development of a better and healthy market for bio informatics in India
• Some of the key areas and steps targeted by the GoI includes:
Enhancing bioinformatics capabilities in the nation and resource integration
Collaborate with foreign countries and create an effective scope for globalization
Provide extramural support for research projects and sufficient coverage on
intellectual properties
Impart both short term as well as long term training so as to churn out quality human
resource pool for the industry
Encourage the market by preparing market Restructuring of the apex bodies to in such a
12BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
Encourage the market by preparing market channels for products and services
manner so that they can work with utmost efficiency
SAMPLE Major Public Companies ‐ Summary
180,000
200,000
Net Profit/Loss
Size of the Bubble represents Market Capitalization in INR mn
139,006.4
413 944 9
120,000
140,000
160,000
413,944.9
60,000
80,000
100,000
436,001.0
0
20,000
40,000
‐20,000
‐50,000 0 50,000 100,000 150,000 200,000 250,000 300,000 350,000 400,000 450,000 500,000 550,000 600,000
Total income
cba
13BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
Note: All figures are in INR mn and are based on the latest financials available
SAMPLE Public: Domestic Company – Player A (1/x)
Company Information Offices and Centres – India
Corporate Address
Tel No.
Fax No.
Website
Year of Incorporation
Noida
Investors
Ticker Symbol
Stock ExchangeHead Office
Key People
Investors
Current & Pending Investors Prior Investors
N D i tiName Designation
14BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
SAMPLE Public: Domestic Company – Player A (2/x)
i i l S h K iFinancial Snapshot Key Ratios
Particulars y‐o‐y change (2011‐10)
2011 2010 2009 2008
Profitability RatiosOperating Margin 0.12 12.56% 12.43% 16.23% 16.75%
Net Profit/LossTotal Income
160.1122.7
104 8150
200
100
150INR bnINR bn
Net Margin ‐0.73 85.71% 86.44% 81.35% 80.82%
Profit Before Tax Margin 1.34 13.34% 12.00% 15.30% 15.26%
Return on Equity 10.58 179.20% 168.61% 172.44% 149.59%
Return on Capital Employed 3.11 21.18% 18.07% 33.85% 30.83%
Return on Working Capital 19.14 431.86% 412.72% ‐972.69% 542.40%
Return on Assets 14.52 98.70% 84.19% 72.50% 92.07%
104.877.5
0
50
100
150
0
50
100
2011201020092008
Financial Summary
• The company incurred a net profit of INR 137.2 bn in FY 2011, as compared to net profit of INR 106 bn in FY 2010
• The company reported total income of INR 160.1 bn in FY 2011, as compared to INR 122 7 bn in FY 2010
Return on Fixed Assets 48.92 647.50% 598.58% 558.37% 506.11%
Cost RatiosOperating costs (% of Sales) N.A. 0.00% 0.00% 0.00% 0.00%
Administration costs (% of Sales)
‐1.53 11.87% 13.40% 14.27% 15.83%
Interest costs (% of Sales) ‐0.44 0.90% 1.33% 0.53% 0.18%compared to INR 122.7 bn in FY 2010
• The company earned an operating margin of 12.56 per cent in FY 2011, an increase of 0.12 percentage points over FY 2010
• The company reported debt to equity ratio of 0.82 in FY 2011, an increase of 18.68 per cent over FY 2010
Interest costs (% of Sales) % % % %
Liquidity RatiosCurrent Ratio 6.31% 1.72 1.62 0.87 1.45
Cash Ratio ‐3.58% 0.56 0.58 0.29 0.92
Leverage RatiosDebt to Equity Ratio ‐18.68% 0.82 1.00 1.38 0.62
b i l iKey Financial Performance Indicators
Indicators Value (19/07/2012)Market Capitalization (INR bn)* 331.07Total Enterprise Value (INR bn)* 333.04EPS (INR)
Debt to Capital Ratio ‐32.75% 0.19 0.28 0.37 0.01
Interest Coverage Ratio 50.85% 14.23 9.44 31.37 96.33
Efficiency RatiosFixed Asset Turnover 8.42% 7.42 6.85 6.70 6.11
Asset Turnover 17.51% 1.13 0.96 0.87 1.11
Current Asset Turnover 14.94% 2.07 1.80 1.75 2.02
15BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
EPS (INR) 34.85PE Ratio (Absolute) 13.75
Working Capital Turnover 4.88% 4.95 4.72 ‐11.67 6.55
Capital Employed Turnover 6.52% 2.05 1.93 2.07 1.81
Improved Decline* The numbers correspond to the data as on 18th Jun, 2012
SAMPLE Public: Domestic Company – Player A (3/x)
Key Business Segments Key Geographic Segments
cba
100%
dcba
6%8%11%12% 23%23%0%
50%
100%157,304
71%
121,363
69%
102,294
16%
73%
75,628
15%
73%
30% 29% 28% 27%
5%5%5%
50%
100%
13%
55%
10%
56%
11%
54%
6% 9%
54%
Key Recent Developments
Description News
0%
2011201020092008
5%5%5%0%
2011201020092008
6%
Note: Business Segments and Geographic Segments are based on total revenues
Overview
Industries Catered
Business ServicesBusiness Services
16BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
SAMPLE Public: Domestic Company – Player A (4/x)
Segments
Clinical data management
Research and Development Manufacturing Sales & Marketing
Factory solutions Consulting servicesg
Data analysis
y
Enterprise solutions
Automation solutions
Consultancy solutions
g
Sales support services
Marketing management
Sales force management
Packaged applications
17BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
SAMPLE Public: Domestic Company – Player A (5/x)
Vendor expertise
One stop solution for meeting regulatory compliances
HL7, HIPAA and SOX certified professionals
Hi hl t d lt tHighly reputed consultants
What’s in store for Clients?
Well structured methodology for ensuring compliance
Compliance gap analysis
Remediation of applications for regulatory compliance
Compliance testing
Faster review of labeling
18BIO INFORMATICS RESEARCH IN INDIA 2012.PPT
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