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Malignant Bone Tumors
by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough
J Bone Joint Surg AmVolume 83(11):1728-1745
November 1, 2001
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 2: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/2.jpg)
Figs. 1-A and 1-B A ten-year-old boy with osteosarcoma in the knee.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
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Figs. 1-A and 1-B A ten-year-old boy with osteosarcoma in the knee.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 4: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/4.jpg)
Anteroposterior radiograph of the femur in a nineteen-year-old woman, revealing a Ewing sarcoma.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 5: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/5.jpg)
Photomicrograph of a typical Ewing sarcoma, showing small, round, uniform cells with scant cytoplasm (magnification, 60).
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 6: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/6.jpg)
Figs. 4-A and 4-B A seventeen-year-old girl with Ewing sarcoma in the right femur.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 7: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/7.jpg)
Figs. 4-A and 4-B A seventeen-year-old girl with Ewing sarcoma in the right femur.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 8: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/8.jpg)
Axial computed tomography scan revealing a large soft-tissue mass on the right side of the pelvis of a patient with Ewing sarcoma.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 9: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/9.jpg)
Figs. 6-A through 6-E A nineteen-year-old man with Ewing sarcoma in the proximal aspect of the femur.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
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Figs. 6-A through 6-E A nineteen-year-old man with Ewing sarcoma in the proximal aspect of the femur.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
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Axial magnetic resonance image made prior to chemotherapy, revealing a large circumferential soft-tissue mass and involvement of the intramedullary canal.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
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The soft-tissue mass greatly decreased in size following neoadjuvant chemotherapy.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 13: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/13.jpg)
Postoperative anteroposterior radiograph of the proximal part of the femur after wide resection and reconstruction with use of an allograft-prosthesis composite.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
![Page 14: Malignant Bone Tumors by C. Parker Gibbs, Kristy Weber, and Mark T. Scarborough J Bone Joint Surg Am Volume 83(11):1728-1745 November 1, 2001 ©2001 by](https://reader035.vdocuments.us/reader035/viewer/2022062515/56649c9e5503460f9495da7f/html5/thumbnails/14.jpg)
Figs. 7-A through 7-E A forty-five-year-old woman who had pain in the left hip.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
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A technetium-99 bone scan showing a marked increase in uptake in the proximal part of the left femur and no other apparent lesions.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
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Magnetic resonance imaging confirmed that the tumor involved the medullary cavity of the femur and extended into the soft tissue.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
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Computed axial tomography scan showing the amount of bone destruction and the soft-tissue extension.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.
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Histological findings were consistent with an intermediate-grade chondrosarcoma.
C. Parker Gibbs, Jr. et al. J Bone Joint Surg Am 2001;83:1728-1745
©2001 by The Journal of Bone and Joint Surgery, Inc.