Download - Is that a cholesteatoma, or what?
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NCRARNATIONAL CENTER FOR REHABILITATIVE AUDITORY RESEARCH
Is that a cholesteatoma, or what?
Tim Hullar, MD• Staff Surgeon, Division of Otolaryngology-Head and Neck Surgery• Research Investigator, NCRAR• VA Portland Medical Center
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Cholesteatoma
• Definition– “Epidermal inclusion cysts of the middle ear”– Have nothing to do with cholesterol– Are essentially skin in the wrong place
– “Epidermoid” is the same thing, except form during development around the brain
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Manifestations of cholesteatoma
• Usually not painful• Draining ear (pus, foul smelling)• Itchy• Hearing loss
• Dizziness
• Meningitis• Brain abscess (seizure, stroke, death)
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Types of cholesteatoma
• Congenital– Born with it; defect of development– Rarest
• Primary acquired– Most common– Usually due to Eustachian tube dysfunction– Arises from retraction pocket
• Secondary acquired– Iatrogenic; secondary to perforation
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Pathogenesis of cholesteatoma
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Normal anatomy
Lateral process of
malleus
Eustachian tube orifice
Pars flaccida
Incus
Round window
Manubrium (handle) of
malleus
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Congenital
• Pearly mass behind intact eardrum
• Begins in antero-superior quadrant
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Primary acquired
• Usually begins in pars flaccida, adjacent to lateral process of the malleus.
• Often erodes bone
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Eustachian tube ventilation
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Primary acquired cholesteatomaAlso called an “attic” cholesteatoma
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Risk factors for primary acquired cholesteatoma
• Parents with Eustachian tube dysfunction• History of middle ear disease• Exposure to allergens, smoke• Previous cholesteatoma
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Primary acquired
• Attic cholesteatoma– Significant scutal
erosion with squamous tissue
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Primary acquired
• Complete atelectasis of the middle ear space– Scutal and
ossicular erosion with retraction pockets
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Primary acquired
• Advanced attic cholesteatoma– Much squamous
debris– Complete loss of
ossicles (lateral process of malleus may be present)
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Secondary acquired cholesteatoma
• No attic retraction pocket
• Commonly occurs after a PE tube, blast
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Cholesteatoma?
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Cartilage graft and myringosclerosis
Cartilage graft
• Exact same color as cholesteatoma
• Drum usuallysmooth over it
• Can see sharp edges
• History of surgery
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Cholesteatoma?
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Secondary acquired
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Cholesteatoma?
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Primary acquired
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Cholesteatoma?
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Middle ear atelectasis; atrophic drum
• Dry• Often fluid
behind• No perforation
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Cholesteatoma?
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Perforation with chronic inflammation
• Perforation with chronic inflammation– Smooth– Featureless– No
squamous debris
– More wet than dry
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Cholesteatoma?
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A two-fer: Primary AND secondary
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Cholesteatoma?
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Tympanosclerosis
• Tympanosclerosis• Granular• Within drum• Normal shape
drum (no retraction)
• Centered on drum
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Cholesteatoma?
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Exostosis
• Bony masses• In external
canal• Can create a
canal cholesteatoma
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Cholesteatoma?
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“Keratin pearl” usually postop
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Cholesteatoma?
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Glomus tympanicum
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Cholesteatoma?
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Bullous myringitis
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Cholesteatoma?
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Otitis externa, or cholesteatoma
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Cholesteatoma?
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Canal cholesteatoma
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Cholesteatoma?
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Otitis media
• Bulging, red• Painful
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Cholesteatoma?
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Fungal otitis externa
• Spores
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Cholesteatoma?
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Secondary acquired
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Cholesteatoma?
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Primary or secondary acquired