Brand Name: Hextend GENERIC NAME: 6% Hetastarch in Lactated Electrolyte InectionMANUFACTURER: Biotime inc!DATE OF FDA APPROVAL: No"em#er $%&'DESCRIPTION: Hextend is a sterile medical I( sol)tion )sed as a #lood *lasma "ol)me ex*ander to re*lace #lood "ol)me lost in ro)tine s)r+ery, emer+ency tra)ma s)r+ery and other a**lications, a condition -no.n as hy*o"olemia /lo. #lood "ol)me0! Hextend1s )ni2)e 3orm)lation contains a modi3ied 3orm o3 starch /6% hetastarch0 s)s*ended in a #alanced electrolyte sol)tion! 4he *rod)ct more closely mirrors the electrolyte #alance o3 #lood than other *rod)cts that contain 6% hetastarch in sim*le salt /sodi)m chloride, or saline0 sol)tions! Hextend is not a s)#stit)te 3or #lood or *lasma!CLASSIFICATION: 5lasma ex*anderMECHANISM OF ACTION:4he #ody a)tomatically detects the lo.er haemo+lo#in le"el, and com*ensatory mechanisms start )*! 4he heart *)m*s more #lood .ith each #eat! 6ince the lost #lood .as re*laced .ith a s)ita#le 3l)id, the no. dil)ted #lood 3lo.s more easily, e"en in the small "essels! As a res)lt o3 chemical chan+es, more oxy+en is released to the tiss)es! 4hese ada*tations are so e33ecti"e that i3 only hal3 o3 the red #lood cells remain, oxy+en deli"ery may still #e a#o)t 78 *ercent o3 normal! A *atient at rest )ses only $8 *ercent o3 the oxy+en a"aila#le in his #lood! In extreme cases, *atients ha"es)r"i"ed .ith a haemo+lo#in le"el o3 $ +9dl, a#o)t &97 the norm, altho)+h le"els this lo. are "erydan+ero)s!INDICATION: Hetastarch is )sed to treat or *re"ent hy*o"olemia /decreased #lood *lasma "ol)me, also called :shoc-:0 that may occ)r as a res)lt o3 serio)s in)ry, s)r+ery, se"ere #lood loss, #)rns, or other tra)ma!SIDE EFFECTS: Consti*ation, na)sea, somnolence, 3ati+)e, headache, di;;iness, dry mo)th, "omitin+ , *r)rit)s, a#dominal *ain, edema *eri*heral, )**er res*iratory tract in3ection FOOD INTERACTION: !not indicatedSPECIAL INSTRUCTION:Hetastarch is inected into a "ein thro)+h an I(! A healthcare *ro"ider .ill +i"e yo) this inection!