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Department of PharmaceuticalSciencesFaculty of Ayurved & Medical Sciences
Gurukul Kangri Vishwavidyalaya,Haridwar
COURSESTRUCTURE
B. PHARM. FIRST SEMESTER
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
Marks
L T C.T. T.A
1. BPM-101 Pharmaceutical Chemistry - I[Inorganic Chemistry]
3 1 3 70 20 10 100
2. BPM-102 Pharmaceutical ChemistryII[Analytical Chemistry]
3 1 3 70 20 10 100
3. BPM-103 Pharmaceutical ChemistryIII[Organic Chemistry-I]
3 1 3 70 20 10 100
4. BPM-104 MathematicsOR 3 1 3 70 20 10 100
5. BPM-105 Biology 1 1 3 40 05 05 50
S.No. Code Practical Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
Marks
P C.T. T.A
6. BPM-151 Pharmaceutical Chemistry - I[Inorganic Chemistry]
3 4 70 20 10 100
7. BPM-152 Pharmaceutical ChemistryII[Analytical Chemistry]
3 4 70 20 10 100
8. BPM-153 Pharmaceutical ChemistryIII[Organic Chemistry-I]
3 4 70 20 10 100
9. BPM-154 Biology 2 4 40 05 05 50
E.S.E. --- End Semester Examination
I.A. --- Marks for Internal Assessment
L --- Lectures
T --- Tutorials
C.T. --- Class TestT.A. --- TeachersAssessment
Note:-BPM- 104 is for students with PCB at class XII level. BPM- 105 and BPM-109 are for thestudents with PCM at class XII level.
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B. PHARM. SECOND SEMESTER
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
Marks
L T C.T. T.A
1. BPM-201 Pharmacology - I [HumanAnatomy & Physiology]
3 1 3 70 20 10 100
2. BPM-202 Pharmaceutics - I [GeneralPharmacy & Dispensing
Pharmacy]
3 1 3 70 20 10 100
3. BPM-203 Pharmaceutics - II [ComputerApplications]
3 1 3 70 20 10 100
4. BPM-204 Environmental Studies 3 1 3 70 20 10 100
S.No. Code Practical Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
Marks
P C.T. T.A
5. BPM-251 Pharmacology - I [HumanAnatomy & Physiology]
3 4 70 20 10 100
6. BPM-252 Pharmaceutics - I [GeneralPharmacy & DispensingPharmacy]
3 4 70 20 10 100
7. BPM-253 Pharmaceutics - II [ComputerApplications]
3 4 70 20 10 100
9. BPM-254 Professional Communication 3 4 70 20 10 100
E.S.E. --- End Semester Examination
I.A. --- Marks for Internal Assessment
L --- LecturesT --- Tutorials
C.T. --- Class Test
T.A. --- TeachersAssessment
Note:BPM-204 will be qualifying paper and the marks obtained will not be counted in the final
result.
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B. PHARM. THIRD SEMESTER
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
Marks
L T C.T. T.A.
1. BPM-301 PharmaceuticsIII[Pharmaceutical Microbiology]
3 1 3 70 20 10 100
2. BPM-302 Pharmaceutics - IV[Pharmaceutical EngineeringOperations]
3 1 3 70 20 10 100
3. BPM-303 Pharmacognosy - I 3 1 3 70 20 10 100
4. BPM-304 Pharmacology - II 3 1 3 70 20 10 100
S.No. Code Practical Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
Marks
P C.T. T.A.
5. BPM-351 PharmaceuticsIII[Pharmaceutical Microbiology]
3 4 70 20 10 100
6. BPM-352 Pharmaceutics - IV[Pharmaceutical EngineeringOperations]
3 4 70 20 10 100
7. BPM-353 Pharmacognosy - I 3 4 70 20 10 100
8. BPM-354 Pharmacology - II 3 4 70 20 10 100
E.S.E. --- End Semester Examination
I.A. --- Marks for Internal AssessmentL --- Lectures
T --- Tutorials
C.T. --- Class TestT.A. --- TeachersAssessment
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B. PHARM. FOURTH SEMESTER
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
Marks
L T C.T. T.A
1. BPM-401 Pharmaceutical ChemistryIV[Physical Chemistry]
3 1 3 70 20 10 100
2. BPM-402 Pharmaceutical ChemistryV[Pharmaceutical Analysis-I]
3 1 3 70 20 10 100
3. BPM-403 Pharmaceutical ChemistryVI[Organic ChemistryII]
3 1 3 70 20 10 100
4. BPM-404 Pharmaceutics-V [HospitalPharmacy]
3 1 3 70 20 10 100
S.No. Code Practical Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Tota
Mark
L C.T. T.A
5. BPM-451 Pharmaceutical ChemistryIV[Physical Chemistry ]
3 4 70 20 10 100
6. BPM-452 Pharmaceutical ChemistryV[Pharmaceutical Analysis-I]
3 4 70 20 10 100
7. BPM-453 Pharmaceutical ChemistryVI[Organic ChemistryII]
3 4 70 20 10 100
8. BPM-454 Pharmaceutics-VI[Pharmaceutical Engineering
Drawing]
3 4 70 20 10 100
E.S.E. --- End Semester Examination
I.A. --- Marks for Internal Assessment
L --- LecturesT --- Tutorials
C.T. --- Class Test
T.A. --- TeachersAssessment
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B. PHARM. FIFTH SEMESTER
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
marks
L T C.T. T.A.
1. BPM-501 Pharmaceutical ChemistryVII [Pharmaceutical Analysis
- II]
3 1 3 70 20 10 100
2 BPM-502 Pharmaceutical ChemistryVIII [Heterocycles,
Carbohydrates, Proteins &
Nucleic Acid]
3 1 3 70 20 10 100
3. BPM-503 Pharmaceutical ChemistryIX [Biochemistry]
3 1 3 70 20 10 100
4. BPM-504 Pharmaceutics - VII [PhysicalPharmacy]
3 1 3 70 20 10 100
S.No. Code Practical Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
marks
P C.T. T.A.
5. BPM-551 Pharmaceutical ChemistryVII [Pharmaceutical Analysis- II]
3 4 70 20 10 100
6. BPM-552 Pharmaceutical Chemistry
VIII [Heterocycles,Carbohydrates, Proteins &
Nucleic Acid]
3 5 70 20 10 100
7. BPM-553 Pharmaceutical Chemistry -IX [Biochemistry]
3 5 70 20 10 100
8. BPM-554 Pharmaceutics - VII [PhysicalPharmacy]
3 5 70 20 10 100
E.S.E. --- End Semester Examination
I.A. --- Marks for Internal Assessment
L --- Lectures
T --- TutorialsC.T. --- Class Test
T.A. --- TeachersAssessment
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B. PHARM. SIXTH SEMESTER
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
marks
L T C.T. T.A.
1. BPM-601 Pharmaceutics - VIII[Formulation Techniquesand Cosmeticology]
3 1 3 70 20 10 100
2. BPM-602 Pharmacognosy- II[Natural Products]
3 1 3 70 20 10 100
3. BPM-603 Pharmacology - III[Pathophysiology and
Toxicology]
3 1 3 70 20 10 100
4. BPM-604 Pharmacology - IV 3 1 3 70 20 10 100
S.No. Code Practical Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
marks
P C.T. T.A.
6. BPM-651 Pharmaceutics - VIII[Formulation Techniques and
Cosmeticology]
3 5 70 20 10 100
7 BPM-652 Pharmacognosy - II [NaturalProducts]
3 5 70 20 10 100
8 BPM-653 Pharmacognosy - III [PlantCollection Tour]
- 3 - - - 100
9. BPM-654 Pharmacology - IV 3 5 70 20 10 100
E.S.E. --- End Semester Examination
I.A. --- Marks for Internal Assessment
L --- Lectures
T --- TutorialsC.T. --- Class Test
T.A. --- TeachersAssessment
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B. PHARM. SEVENTH SEMESTER
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
marks
L T C.T. T.A.
1. BPM-701 Pharmaceutical ChemistryX[Medicinal Chemistry - I]
3 1 3 70 20 10 100
2. BPM-702 Pharmaceutics - IX[Pharmaceutical Management]
3 1 3 70 20 10 100
3. BPM-703 PharmaceuticsX[Pharmaceutical Technology]
3 1 3 70 20 10 100
4. BPM-704 PharmaceuticsXI[Pharmacokinetics &
Biopharmaceutics]
3 1 3 70 20 10 100
5. BPM-705 Pharmaceutics - XII[Pharmaceutical Jurisprudence]
3 1 3 70 20 10 100
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
marks
P C.T. T.A.
6. BPM-751 Pharmaceutical Chemistry- X[Medicinal Chemistry - I]
3 4 70 20 10 100
7. BPM-752 PharmaceuticsX[Pharmaceutical Technology]
3 5 70 20 10 100
8. BPM-753 Pharmaceutics - XI[Pharmacokinetics &
Biopharmaceutics]
3 5 70 20 10 100
E.S.E. --- End Semester Examination
I.A. --- Marks for Internal Assessment
L --- LecturesT --- Tutorials
C.T. --- Class Test
T.A. --- TeachersAssessment
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B. PHARM. EIGHTH SEMESTER
S.No. Code Theory Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
marks
L T C.T. T.A.
1. BPM-801 Pharmaceutical ChemistryXI [Medicinal Chemistry -
II]
3 1 3 70 20 10 100
2. BPM-802 Pharmaceutical ChemistryXII [Medicinal Chemistry -
III]
3 1 3 70 20 10 100
3. BPM-803 PharmacologyV [ClinicalPharmacology]
3 1 3 70 20 10 100
4. BPM-804 PharmacognosyIV
[PharmaceuticalBiotechnology]
3 1 3 70 20 10 100
S.No. Code Practical Course Hrs/
Week
Exam
Hrs.
E.S.E. I.A. Total
marks
L C.T. T.A.
5. BPM-851 Pharmaceutical ChemistryXI& XII [Medicinal Chemistry-II
& III]
3 5 70 20 10 100
6 BPM-852 Pharmacology - V [ Clinical
Pharmacology]
3 5 70 20 10 100
7. BPM-853 Pharmacognosy - IV[PharmaceuticalBiotechnology]
3 5 70 20 10 100
8. BPM-854 Pharmaceutics - XIII [IndustrialTour]
0 3 - - 100
E.S.E. --- End Semester Examination
I.A. --- Marks for Internal AssessmentL --- Lectures
T --- Tutorials
C.T. --- Class TestT.A. --- TeachersAssessment
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COURSESTRUCTURE
Theory
B.PHARM. FIRST SEMESTER
BPM-101 Pharmaceutical Chemistry - I [Inorganic Chemistry]
BPM-102 Pharmaceutical ChemistryII [Analytical Chemistry]BPM-103 Pharmaceutical ChemistryIII [Organic Chemistry-I]
BPM-104 MathematicsORBPM-105 Biology
Practical
BPM-151 Pharmaceutical Chemistry - I [Inorganic Chemistry]BPM-152 Pharmaceutical ChemistryII [Analytical Chemistry]BPM-153 Pharmaceutical ChemistryIII [Organic Chemistry-I]
BPM-154 Biology
TheoryB.PHARM. SECOND SEMESTER
BPM-201 Pharmacology - I [Human Anatomy & Physiology]BPM-202 Pharmaceutics - I [General Pharmacy & Dispensing Pharmacy]
BPM-203 Pharmaceutics - II [Computer Applications]
BPM-204 Environmental Studies
Practical
BPM-251 Pharmacology - I [Human Anatomy & Physiology]BPM-252 Pharmaceutics - I [General Pharmacy & Dispensing Pharmacy]BPM-253 Pharmaceutics - II [Computer Applications]
BPM-254 Professional Communication
B.PHARM. THIRD SEMESTER
TheoryBPM-301 PharmaceuticsIII [Pharmaceutical Microbiology]BPM-302 Pharmaceutics - IV [Pharmaceutical Engineering Operations]
BPM-303 PharmacognosyI
BPM-304 PharmacologyII
PracticalBPM-351 PharmaceuticsIII [Pharmaceutical Microbiology]BPM-352 PharmaceuticsIV [Pharmaceutical Engineering Operations]
BPM-353 PharmacognosyIBPM-354 Pharmacology - II
Theory
B.PHARM. FOURTH SEMESTER
BPM-401 Pharmaceutical ChemistryIV [Physical Chemistry]
BPM-402 Pharmaceutical ChemistryV [Pharmaceutical Analysis-I]
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BPM-403 Pharmaceutical ChemistryVI [Organic ChemistryII]BPM-404 Pharmaceutics-V [Hospital Pharmacy]
PracticalBPM-451 Pharmaceutical ChemistryIV [Physical Chemistry]BPM-452 Pharmaceutical ChemistryV [Pharmaceutical Analysis-I]
BPM-453 Pharmaceutical ChemistryVI [Organic ChemistryII]
BPM-454 Pharmaceutics-VI [Pharmaceutical Engineering Drawing]
Theory
B.PHARM. FIFTH SEMESTER
BPM-501 Pharmaceutical ChemistryVII [Pharmaceutical Analysis - II]
BPM-502 Pharmaceutical ChemistryVIII [Heterocycles, Carbohydrates, Proteins & Nucleic
Acid]BPM-503 Pharmaceutical ChemistryIX [Biochemistry]
BPM-504 Pharmaceutics - VII [Physical Pharmacy]
Practical
BPM-551 Pharmaceutical ChemistryVII [Pharmaceutical Analysis - II]BPM-552 Pharmaceutical ChemistryVIII [Heterocycles, Carbohydrates, Proteins & Nucleic
Acid]BPM-553 Pharmaceutical Chemistry - IX [Biochemistry]
BPM-554 Pharmaceutics - VII [Physical Pharmacy]
Theory
B.PHARM. SIXTH SEMESTER
BPM-601 Pharmaceutics - VIII [Formulation Techniques and CosmeticologyBPM-602 Pharmacognosy - II [Natural Products]
BPM-603 Pharmacology - III [Pathophysiology and Toxicology]
BPM-604 PharmacologyIV
Practical
BPM-651 Pharmaceutics - VIII [Formulation Techniques and Cosmeticology]BPM-652 Pharmacognosy - II [Natural Products]BPM-653 Pharmacognosy - III [Plant Collection Tour]
BPM-654 PharmacologyIV
Theory
B.PHARM. SEVENTH SEMESTER
BPM-701 Pharmaceutical ChemistryX [Medicinal Chemistry - I]
BPM-702 Pharmaceutics - IX [Pharmaceutical Management]BPM-703 PharmaceuticsX [Pharmaceutical Technology]
BPM-704 PharmaceuticsXI [Pharmacokinetics & Biopharmaceutics]
BPM-705 Pharmaceutics - X II [Pharmaceutical Jurisprudence]
PracticalBPM-751 Pharmaceutical Chemistry- X [Medicinal Chemistry - I]BPM-752 PharmaceuticsX [Pharmaceutical Technology]
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BPM-753 Pharmaceutics - XI [Pharmacokinetics & Biopharmaceutics]
B.PHARM. EIGHTH SEMESTER
TheoryBPM-801 Pharmaceutical ChemistryXI [Medicinal Chemistry - II]BPM-802 Pharmaceutical ChemistryXII [Medicinal Chemistry - III]
BPM-803 PharmacologyV [Clinical Pharmacology]BPM-804 Pharmacognosy - IV [Pharmaceutical Biotechnology]
PracticalBPM-851 Pharmaceutical ChemistryXI & XII [Medicinal Chemistry-II & III]BPM-852 Pharmacology - V [Clinical Pharmacology]
BPM-853 Pharmacognosy - IV [Pharmaceutical Biotechnology]
BPM-854 Pharmaceutics - XIII [Industrial Tour]
Note:-BPM- 104 is for students with PCB at class XII level. BPM-105 and BPM-109 are for thestudents with PCM at class XII level. BPM-204 will be qualifying paper and the marks obtained
will not be counted in the final result.
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FIRST SEMESTER
THEORY
BPM101
PHARMACEUTICAL CHEMISTRYI [INORGANIC CHEMISTRY]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1 (L+T);Duration of Exam.3 hrs
Instructions to examiners:Two questions should be asked from each unit. Students shall be required to attem
one question from each unit. In all, five questions shall be attempted. All questions shall be of 14 marks each.
NOTE:Topics 3-11 will be treated coveringONLYan outline of methods of preparation, test for identity a
purity including limit test, chemical properties, assay procedures and Pharmaceutical uses.
UNIT I
1. Arrhenius theory for electrolytic dissociation in solutions. Concepts of Acids and Bases, Role of Solv
in deciding the acid-base nature, Common ion effect, Ionic product of water, pH, Buffers, Henders
Hesselbalsch equation, Hydrolysis of salts.
2. Impurities in Pharmaceutical substances and their control.
3. Pharmaceutical aids and necessities: Acids, bases, buffers, antioxidants, water and pharmaceutic
acceptable glass.
UNITII
4. Major Intra and extra-cellular electrolytes: Major physiological ions, electrolytes used in replacem
therapy: Physiological acid-base balance; electrolytes used in acid base therapy; electrolyte combina
therapy.
5. Essential and trace elements, Copper, Zinc, Chromium, Manganese, Molybdenum, Selenium, Sulphur
Iodine.
UNITIII
6. Gastrointestinal agents: Acidifying agents; antacids protective and absorbents: saline cathartics.
7. Topical agents: Protectives, antimicrobials and astringents.
UNITIV
8. Dental Products: Anticaries agents and dentifrices.
9. Nuclear chemistry: Nuclear composition, forces and stability, isotopes, measurement of radioactiv
modes of decay, half life period, artificial radioactivity, application in Pharmacy, Radiopharmaceutic
Radiopharmaceutical preparations and radiopaque contrast media.
UNITV
10. Co-ordination compounds and complexations.
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FIRST SEMESTER
11. Miscellaneous Inorganic Pharmaceutical Agents: Inhalants, respiratory stimulants, expectorants
emetics, antidotes, tableting aids and suspending agents.
List of books recommended (Latest editions unless specified):
1. J. H. Block, E. Roche, T. O. Soine and C.O. Wilson, Inorganic Medicinal and Pharmaceutical Chemis
Lea & Febiger, Philadelphia, PA, USA.
2. L. M. Athorton, Bantley and Drivas, Text Book of Pharmaceutical Chemistry, Oxford University Pr
Delhi.
3. Indian Pharmacopoeia Vol. I & II, Ministry of Health, Government of India (Latest Edition).
4. A. H. Beckett and J. B. Stenlake, Practical Pharmaceutical Chemistry, Part I, The Athlons Pre
University of London, London.
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FIRST SEMESTER
THEORY
BPM102
PHARMACEUTICAL CHEMISTRYII [ANALYTICAL CHEMISTRY] Max.
Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1 (L+T);Duration of exam: 3 hrs
Instructions to examiners: Two questions should be asked from each unit. Students shall be required to attem
one question from each unit. In all, five questions shall be attempted. All questions shall be of 14 marks each.
UNITI
1. Accuracy and Precision. Expressing the accuracy and precision - Error, Relative error, Deviation, M
deviation, relative mean deviation, standard deviation, relative standard deviation, Variance, Coeffic
of variation.
2. Classification of errors Systematic errors, Random errors and Mistakes, Additive and proportion
errors. Minimization of errors.
3. Significant figures, Rejection Quotient test, Method of least squares.
4. Numerical problems related to the above topics.
UNITII
5. Concept of Mol, g-atom, g-ion, g-formula weight and g-equivalent. Concept of Oxidation-reduct
Oxidation number, balancing of equations, Reactions of commonly used oxidizing reducing age
Equivalent weight of acids and bases, Equivalent weight of oxidizing and reducing agents. Law
equivalence as the basis of Acid-Base titrations and Redox titrations.6. Standard solutions: Expressing the concentration or strength of solutions In Percentage, g/
Normality, m. eq. /ml, Molarity, Formality, Molality, Mol fraction and in P.P.M. Expressing
concentration of H2O2solutions. Concentrations of gases in liquids. Expressing the percentage of SO
Oleum.
7. Numerical problems related to the above topics.
UNITIII
8. Different types ofAcidBase titrations(Strong acidStrong base, Strong acid- Weak base, Weak a
strong base, and Weak acid- weak base).
9. AcidBase indicators, Choice and Theory of these indicators.
10. Multi-step equilibrium, Polyprotic, Polyamine and amino acid systems. Application of acid base titrati
in assay of NaOH, CaCO3& Na2CO3.
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FIRST SEMESTER
11.Non-aqueous Titrations: Theoretical consideration, acid base equilibria in non-aqueous media, acid-b
titrations, indicators, applications.
UNITIV
12.Redox titrations: Iodometry and Iodimetry. Titrations involving Ceric sulphate, potassium iodate,
potassium bromate, Potassium permanganate, Potassium dichromate. Redox indicators (Internal, Exte
and self indicators).
13.Complexometric Titrations: Complexation and chelation, Warner theory and electronic structur
complex ions, stability constants. Types of complexometric titrations, indicators for complexome
titrations, factors influencing the stability of complexes, EDTA-metal ion complexes, determination
hardness of water.
14.Precipitation titrations, Preferential adsorption theory. Functioning of Adsorption indicators. Moh
method and Volhards method.
UNITV
15.Miscellaneous Methods of Analysis: Diazotization titrations, Kjeldahls method for estimation
nitrogen in inorganic compounds, organic compounds, soil and fertilizers, Karl-Fischer titration
estimation of water.
16.Gravimetric Analysis: Precipitation technique related to solubility product. Elementary idea of Collo
state. Super saturation, Co-precipitation and Post precipitation. Digestion, washing of precipit
Filtration, Filter papers and crucibles, Ignition of precipitate. Thermo gravimetric curves. Spec
examples like estimation of barium as barium sulphate, aluminium as aluminium oxide, calcium
calcium oxalate and magnesium as magnesium pyrophosphate, Organic precipitants.
List of books recommended (Latest editions unless specified):
1. K.A.ConnersA Text Book of Pharmaceutical AnalysisWilley Interscience.
2. J.Medham, R.C.Denny, J.D.Barnes, M. Thomas and G.H. JefferyVogels Text book of Quantitat
Analysis. Pearson Education Asia.
3. A.H.Beckett and J.B.StenlakePractical Pharmaceutical AnalysisVol. I & II. The Antherden Pr
of the University, London.
4. British PharmacopoeiaHer Majestys Stationary Office, University Press, Cambridge.
5. A.AlexeyevQuantitative analysisCBS Publishers and Distributors, New Delhi.
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BACHELOR OF PHARMACY
FIRST SEMESTER
THEORY
BPM103
PHARMACEUTICAL CHEMISTRYIII [ORGANIC CHEMISTRYI] Max.
Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1 (L+T);Duration of exam: 3 hrs
Instructions to examiners:Two questions should be asked from each unit. Students shall be required to attem
one question from each unit. In all, five questions shall be attempted. All questions shall be of 14 marks each.
UNIT I
1. Structure and Properties: Covalent bonding, Hybridization, Multiple bonds. Electronegativity, Dip
moment, Inductive and field effects. Bond lengths, bond angle and bond energies. Delocalizat
Hyperconjugation, Tautomerism. Hydrogen bonding. Organic acids and bases.
2. Stereochemistry (Basic Concepts only): Optical activity, Chirality, Enantiomers, Diastereomers, D/L
R/S nomenclature. Recemic mixture and resolution. Geometrical isomerism.
UNITII
3. Alkanes: Nomenclature, Physical properties, Industrial source and preparation. Halogenation, Combus
and pyrolitic reactions.
4. Cycloalkanes: Nomenclature, Physical properties, Industrial source and preparation. Bayers strain the
Conformations of cyclohexane.
5. Alkenes, Dienes and Alkynes: Nomenclature, physical properties, industrial source, preparation
addition reactions. Polymerization of dienes. Acidity of alkynes.UNITIII
6. Alcohols, Alkyl Halides and Ethers: Nomenclature, General methods of preparation, physical proper
chemical reactions.
7. Aliphatic nucleophilic substitution: SN1, SN
2 mechanisms. Hydrolysis of esters.
UNITIV
8. Addition to carbon/carbon and carbon/hetero multiple bonds: Electrophilic, nucleophilic and free rad
addition to carbon-carbon multiple bonds, Michael, Mannich, Grignard, Reformatsky, Witting and Pe
reactions. Aldol, Knoevengal and Bezoin condensations.
9. Elimination Reactions: E1, E2, mechanisms, Saytzeff and Hoffman rules.
UNITV
10. Aldehyde and Ketones: Structure, nomenclature, physical properties, industrial source, preparation
reactions. Acidity of hydrogens.
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FIRST SEMESTER
11. Active methylene compounds: Ethyl acetoacetate synthesis and applications in organic synthesis.
List of books recommended (Latest editions unless specified)
1. R.T. Morrison and R.N. Boyd. Organic Chemistry, Allyl and Bacon, Inc., Boston, USA.
2. I.L. Finar, Organic Chemistry, Vol. I and II, The English Language Book Society.
3. P. Sykes, A Guidebook to Mechanisms in Organic Chemistry, Orient Longman, New Delhi.
4. J. March, Advanced Organic Chemistry, Reaction, Mechanisms and structure, Wiley Eastern, New Del
5. S. Pine, Organic Chemistry, McGraw Hill, 1987.
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BACHELOR OF PHARMACY
FIRST SEMESTER
THEORY
BPM104
MATHEMATICS
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1 (L+T);Duration of exam: 3 hrs
Instructions to examiners:Two questions should be asked from each unit. Students shall be required to attem
one question from each unit. In all, five questions shall be attempted. All questions shall be of 14 marks each.
UNIT I
1. Algebra: Arithmetic, geometric & harmonic progressions, evaluation ofn, n2
and n3
(Element
treatment only )
2. Trigonometry: Measurement of angle, trigonometrical ratio of sum and difference of ang
transformation formulae, trigonometrical-ratios of multiple and submultiple angles. Logarith
(Elementary treatment only).
UNITII
3. Analytical plans geometry:Cartesian coordinates system, distance between two points, area of triang
Section formula, equation of straight line (slope intercept form, point slope form, two point slope fo
intercept form, general equation of first degree).
UNITIII
4. Calculus: Limit and continuity (elementary concept only), definition of differential coeffic
differential coefficient of trigonometric functions (exclusive inverse circular and hyperbolic function
differential coefficient ofa constant and function, logex, ex, ax, sum of two or more than two functi
product of two functions, quotient of two functions, parametric and implicit function. Differentiating
method of substitution, derivative of a function of second order derivatives. Application of derivative
rate measurer. Maxima and minima of a function of single variable. (elementary treatment only)
UNITIV
5. Integration:Integration as inverse of differentiation, indefinite integral of standards forms, integration
sum and difference of two functions. Integration by substitution and integration by parts.
6. Differential Equation:Formation of a differential equation, order and degree, differential equation of
first order and first degree (equation solvable by separation by the variables, linear equation of the f
order), linear differential equation with constant coefficients.
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FIRST SEMESTER
7. Statistics:
UNITV
Collection, presentation and diagrammatic representation of data, frequency distribution, mea
of central tendency.
Probability: Sample spaces, algebra of events, axiomatic approach to probability, finite sam
spaces combinational problem.
Test of significance: One tailed and two tailed tests, student t-test for single mean, differe
between two means tests of correlation coefficient chi-square test of goodness of fit
independence of attributes, chi-square test for population variance.
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List of books recommended (Latest unless specified)
1. Gorakh Prasad "Differential calculus
2. Elementary Engineering MathematicsB. S. Grewal Khanna Publishers, Delhi.
3. Gorakh PrasadIntegral Calculus
4. Examples in Statistics by H.C. Sexana, Atma Ram and Sons, Delhi.
5. AyresMathematics and Statistics for students of Pharmacy,
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FIRST SEMESTER
THEORY
BPM105
BIOLOGY
Max. Marks: 40;Pass percentage: 40;Hrs/ wk: 1+1 (L+T);Duration of exam: 3 hrs
Instructions to examiners:Two questions should be asked from each unit. Students shall be required to attem
one question from each unit. In all, five questions shall be attempted. All questions shall be of 08 marks each.
UNIT I
1. Methods of classification of plants.
UNITII
2. Plant Cell: Its structure and non living inclusions: mitosis and meiosis; different types of plant tiss
and their functions.
UNITIII
3. Morphology and histology of root, stem, bark, wood, leaf, flower, fruit and seed, Modification of root
stem.
UNITIV
4. General survey of animal kingdom; Structure and life history of parasites as illustrated by amoe
antanoeba, trypanosoma, plasmodium, taenia, ascaries, schistosoma, oxyuris, and ancylostoma.
UNITV
5. General structure and life history of insects like mosquito, housefly, mites and silkworm.
List of books recommended (Latest editions unless specified):
1. A.C.DuttaBotany for degree studentsOxford.
2. Marshall & WilliamsText Book of ZoologyCBS Publishers & Distributors, New Delhi.
3. FahnPlant AnatomyAdsitya Books private Limited, New Delhi.
4. Weiz B. PaulLaboratory Manual in science of BiologyMc Graw- Hill Book Company.
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FIRST SEMESTER
PRACTICAL
BPM151
PHARMACEUTICAL CHEMISTRYI [INORGANIC CHEMISTRY]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of exam: 4 hrs
Experiments related to the following:
1. The background and systematic qualitative analysis of Inorganic mixtures containing upto 4 radicals.
2. Quantitative analysis of Inorganic compounds.
3. Limit tests for impurities in Pharmaceutical compounds.
4. Preparation and Purification of selected Inorganic Pharmaceutical substances.
NOTE:Any other experiment(s) may be included in support of theoretical aspects of the course.
Distribution of Marks:
1. Experiments : 50 marks
2. Record : 10 marks
3. Viva voce : 10 marks
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FIRST SEMESTER
PRACTICAL
BPM152
PHARMACEUTICAL CHEMISTRYII [ANALYTICAL CHEMISTRY]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of Exam.4 hrs
Experiments related to the following:
1. Standardization of analytical weights and calibration of volumetric apparatus.
2. Acid Base Titrations: Preparation and standardization of acids and bases; some exercises related
determination of acids and bases separately or in mixture form some official assay procedures e.g. b
acid shall also be covered.
3. Oxidation-Reduction Titrations: Preparation and standardization of some redox titrants e.g. Potass
permangnate, potassium dichromate, iodine, sodiumthiosulphate etc., Some exercises related
determination of oxidizing and reducing agents in the sample shall be covered. Exercises involv
potassium iodate, potassium bromate, Iodine solution, titanous chloride, sodium 2, 6- dichlorophe
indophenol, & cerric ammonium sulphate be designed.
4. Precipitation Titrations: Preparation and standardization of titrants like silver nitrate and ammon
thiocyanate, titration according to Mohars, Volhards and Fazans methods.
5. Gravimetric analysis: Preparation of Gooch crucible for filtration and use of sintered glass crucib
Determination of water of hydration; some exercises related gravimetric analysis shall be covered.
NOTE:Any other experiment(s) may be included in support of theoretical aspects of the course.
Distribution of Marks:
1. Experiments : 50 marks
2. Record : 10 marks
3. Viva voce : 10 marks
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FIRST SEMESTER
PRACTICAL
BPM153
PHARMACEUTICAL CHEMISTRYIII [ORGANIC CHEMISTRYI]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of Exam.4 hrs
Experiments related to the following:
1. Introduction to various laboratory techniques viz. recrystallization, distillation, sublimation, thin la
chromatography etc.
2. Simple organic preparations involving acetylation, benzylation, substitutions, sulphonation, oxidation
reduction reactions.
3. Identification of simple organic compounds and preparation of suitable simple derivatives.
NOTE:Any other experiment(s) may be included in support of theoretical aspects of the course.
Distribution of Marks:
1. Experiments : 50 marks
2. Record : 10 marks
3. Viva voce : 10 marks
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FIRST SEMESTER
PRACTICAL
BPM154
BIOLOGY
Max. Marks: 40;Pass percentage: 40;Hrs/ wk: 3;Duration of Exam.4 hrs
Experiments related to the following:
1. Morphology of plant parts indicated in theory.
2. Care, use and type of microscopes.
3. Gross identification of slides of structure and life cycle of lower plants, animals mentioned in theory.
4. Preparation, microscopic examination of stem, root and leaf of monocot and dicot plants.
5. Structure of human parasites and insects mentioned in theory with the help of specimens.
Note:Any other experiment (s) may be included in support of theoretical aspects of the course.
NOTE:Any other experiment(s) may be included in support of theoretical aspects of the course.
Distribution of Marks:
1. Experiments : 30 marks
2. Record : 05 marks
3. Viva voce : 05 marks
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SECOND SEMESTER 1
THEORY
BPM201
PHARMACOLOGYI [HUMAN ANATOMY & PHYSIOLOGY]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1(L+T);Duration of exam: 3 hrs
Instructions to examiners: Two questions would be asked from each unit. Students shall be
required to attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
A. ANATOMY
1. Histology & Cytology
UNITI
1. Cell components (Structure and Functions)
2. Structural and functional characteristics of tissues
(a) Epithelial
(b) Connective
(c) Muscle
(d) Nervous
2. Skeletal System
1. Structure (gross and microscopic), composition & functions of skeleton
2. Classification of joints
(a) Fibrous
(b) Cartiligenous
(c) Synovial
3. Classification of synovial joints
4. Types of movements of joints
5. Joints of upper 7 lower limb (basic concepts)
3. Lymphoid organs (Structure and functions)
(a) Spleen
(b) Thymus
(c) Lymph node
B. PHYSIOLOGY
1. Membrane transport
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SECOND SEMESTER 2
2. Body compartments
3. Ionic equilibrium and resting membrane potential
4. Neuron action potential
5. Synaptic transmission
6. Excitation-contraction coupling (Skeletal muscles)
UNIT II
A. Renal system
1. Structure (Gross and microscopic) and function of urinary tract
2. Physiology of urine formation
3. Acid-Base balance
4. Clearance
B. DIGESTIVE SYSTEM
1. Structure (Gross and microscopic) of GI tract
2. GI tract secretion; absorption and digestion of food
3. Structure (Gross and microscopic) & functions of
Liver,
Pancreas
Gall bladder
A. RESPIRATORY SYSTEMUNIT-III
1. Structure (Gross and Microscopic) respiratory tract
2. Respiration (Mechanism & regulation)
3. Respiratory volumes and vital capacity
B.ENDOCRINE SYSTEM
Basic anatomy and physiology of pituitary, thyroid, parathyroid, adrenal glands, pancreas, testes,
ovaries, their hormones and functions.
C. REPRODUCTIVE SYSTEM
1. Male reproductive system, structure (gross and microscopic) and functions
2. Female reproductive system, structure (gross and microscopic) and functions
3. Family planning: Contraception, medical termination of pregnancy
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SECOND SEMESTER 3
A. NEUROSCINCE
Central Nervous system
UNIT-IV
1. Anatomy & functions of different parts of brain and spinal cord
2. Neurohormonal transmission in CNS
3. Reflex action
4. Cranial nerves and their functions
5. Electroencephalogram
Autonomic nervous system:
1. Physiology and functions of the autonomic nervous system
2. Mechanism of neurohormonal transmission in ANS
B.SENSE ORGANS
1. Structure (Gross and Microscopic) and functions of
A. Eye (Vision)
B. Ear (Hearing)
C. Nose (smell and equilibrium)
D. skin (Superficial receptors)
E. Taste buds
A. CARDIOVASCULAR SYSTEM
UNIT-V
1. Structure (gross) of heart & blood vessels & circulation
2. Electrical activity of the heart (ECG)
3. Cardiac muscle mechanics (cardiac cycle and heart sounds)
4. Regulation of cardiac output, blood flow & blood pressure
B.HAEMATOPOIETIC SYSTEM
1. Composition and functions of blood and its cellular components
2. Blood groups and their significance
3. Mechanisms of coagulation
4. Parameter for blood donors, procedure of blood collection and storage.
C. FIRST AID
Emergency treatment of
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1. Shock
2. Burns
3. Poisoning
4. Fractures
5. Snake bites
6. Resuscitation methods
List of books recommended (Latest editions unless specified)
1. Ross & Wilson,Anatomy and Physiology in health and illnessChuchill Livingtone
2. C.C. Chatterjee,Human PhysiologyMedical Allied Agency, Calcutta
3. B.D. ChaurasiaHuman Anatomy, regional & AppliedPart I, II & III. CBS Publishers &
Distributors, New Delhi.
4. C.A. Keele, E. Niel and N. Joels Samson Wrights Applied Physiology Oxford
university Press.
5. N.S. Parmar Health Education and Community Pharmacy CBS Publishers and
Distributors, New Delhi.
6. A.C. Guyton and J.E.HallText Book of Medical Physiology.
7. Grays Human Anatomy, ELBS, London
8. Keel & Neil, Samson Wrights applied PhysiologyWB Saunders company
9. G.J. Tortora and N.P. Anagnodokos Principles of Anatomy & physiology Harper &
Row Publishers, New Delhi.
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SECOND SEMESTER 5
THEORY
BPM202
PHARMACEUTICSI [GENERAL PHARMACY & DISPENSING PHARMACY] Max.
Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1 (L+T);Duration of exam: 3 hrsInstructions to
examiners:Two questions should be asked from each unit. Students shall be required to
attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
Unit-I
1. Definitions and general dispensing procedures including labeling of dispensed products, ethics,
oath and scope of pharmacy.
2. Introduction to official compendia, with emphasis on Indian Pharmacopoeia, British
Pharmacopoeia and United State Pharmacopoeia.
3. Prescription: Handling of prescription, sources of error in prescription, pharmaceutical Latin
terms used in prescription and their English equivalents.
4. Containers, closures, colours, flavours, sweetening agents, antioxidants and preservatives used
in prescriptions.
Unit-II
5. Incompatibilities: Physical and chemical incompatibilities, methods to overcome inorganic
incompatibilities including incompatibilities of metals and their salts, non-metals, acids, alkalis.6. Extraction and extractives: Various methods of extraction including infusion, decoction,
maceration, percolation and digestion. Preparation of infusion, tinctures, dry and soft extracts.
Unit-III
7. Routes of drug administration: Need of dosage forms, therapeutic consideration in dosage form
designing, routes of drug administration and dosage forms for oral, rectal, parenteral,
epicutaneous, ocular, otic and nasal route.
8. Powder dosage form: Standard powders, sieves and their usage in grading, bulk powders and
divided powders for internal and external use. Special powders including insufflations,
effervescent powders and granules.
9. Emulsions and suspensions: Emulsions: Types, emulsifying gents, manufacturing and
identification of emulsions, creaming and cracking and their prevention.Suspensions: flocculated
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SECOND SEMESTER 6
and non-flocculated suspensions, sedimentation, suspending agents, wetting agents, flocculating
agents.
Unit-IV
10. Suppositories: Ideal requirements, bases, manufacturing procedures, packaging and evaluation
11. Semi-solid dosage forms: Definitions, types, mechanism of drug penetration, factors
influencing penetration, semisolid bases and their selection, general formulation of semisolids,
manufacturing procedure, evaluation and packaging.
Unit-V
12. Pharmaceutical Calculations: Posology, calculation of doses for infants, adults and elderly
patients. Percentage solutions, enlarging and reducing recipes, allegation, alcohol dilutions, proof
spirits, isotonic solutions, displacement value.
13. Principles involved and procedures adopted in dispensing of typical preparations like
mixtures, syrups, elixirs, glycerins, mouth washes, gargles, spirits, nasal drops, ear drops,
aromatic waters, emulsions, creams, suspensions, ointment, powders, paste, mucilages, jellies,
suppositories, lozenges, pills, lotions, liniments, inhalations, paints, sprays, tablet, capsule,
triturates.
List of books recommended (Latest editions unless specified)
1. Remingtons Pharmaceutical Sciences Mack Publishing Company, USA.
2. J.W. Copper & G. Gunn, Tutorial Pharmacy, Pitman Books Ltd. London.
3. S.J. Carter, - Dispensing for Pharmaceutical Students 12th Edition, GBS Publishers &
Distributions.485 Bhola Nath Nagar, Shahdara, Delhi32.
4. Theory and Practice of Industrial Pharmacy. Lachman et.al, Varghese Publishing House,
Hind Rajasthan Building, Dadar, Bombay400014.
5. Bentleys Text Book of pharmaceuitcsVol. I & II. Churchill Livinstone
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BACHELOR OF PHARMACY
SECOND SEMESTER 7
THEORY
BPM- 203
PHARMACEUTICSII [COMPUTER APPLICATIONS]
Max. Marks : 70; Pass Percentage : 40; Hrs/ Wk : 3+1 (L+T); Duration of Exam : 3 Hrs
Instructions to examiners: Two questions should be asked from each unit. Students shall be
required to attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
UNITI
A Simple Model of Computer, Characteristics of Computer, Problem Solving Using Computers.
Representation of Characters in Computers, Representation of Integers, Representation of
Fractions. Number system: Decimal, Binary, Octal and Hexadecimal numbers and their
arithmetic; Computer Generation and Classification: First, Second, Third, Fourth, Fifth
Generation of Computers.
UNIT- II
Programming Language:Classification machine code, assembly language, high level language,
compiling a HLL Program, fourth generation languages.
Operating Systems:Need of Operating System, Type of Operating systems(single user, multi-
user, batch, multiprogrammed, time sharing), Internal & external commands of MS- DOS,Features of Windows based O.S., creating, copying, deleting and renaming files/ folders.
UNIT- III
Basic Features of C language: Data types, Constants, Variables, I/O functions, Arithmetic
operators, Unary operators, Relational and Logical Operators, the conditional operators, Control
structures of C, Switch Statements.
UNIT- IV
Arrays :Defining an array, processing an array, Arrays and strings.
Functions:Defining and accessing a simple function.
Pointer: Simple concept, Function using pointer type argument(s).
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SECOND SEMESTER 8
UNIT- V
Computers and Communication: Types of Communication, Need For Computer
Communication Networks, Internet and WWW, Use of email, search engine, types of sites.
Applications:Role of computers in Pharmaceutical Industries, Use of computers for maintaining
issue & dispatch record of stocks in Pharma company inventory maintenance.
List of books recommended (Latest editions unless specified)
1. V. Rajaraman- Fundamental of Computers (PHI), 2000.
2. B. B. Gottfried: Programming with C (TMH), 1997.
3. D. Comer, Internet and its working, Pearson Education.
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BACHELOR OF PHARMACY
SECOND SEMESTER 9
THEORY
BPM204
ENVIRONMENTAL STUDIES
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1 (L+T);Duration of Exam: 3 hrs
Instructions to examiners: Two questions should be asked from each unit. Students shall be
required to attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
UNITI
1. The Multidisciplinary nature of environmental studies and eco-system
a) Definition, scope and importance of ecology and environment.
b) The ecological components
i. Abiotic components-soil, water light, humidity and temperature
ii. Biotic components and their relationships- symbiosis, mutalism,
commensalisms, parasitism, predation and antibiosis.
c) Concept of an eco-system
d) Structure and function of an eco-system
e) Producers, consumers and decomposers.
f) Energy flow in the eco-system
g) Ecological successionh) Food chain, food webs and ecological pyramids.
i) Introduction, types, characteristics, features, structure and function of the following
ecosystem:
i. Forest Eco-system
ii. Aquatic Eco- system (ponds, streams, lakes, river, oceans, estuaries)
iii. Grassland Eco-system
iv. Desert Eco-system
j) Need of public awareness
2. Natural Resources:
UNITII
a) Renewable and non-renewable resources
b) Natural resources and associated problems.
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i. Forest resources: Use and over-exploitation, deforestation, case studies, timber
extraction, mining, dams and their effects on forest and tribal people.
ii. Water resources: Use and over utilization of surface and ground water, floods, drought,
conflicts over water, dams benefits and problems.
iii. Mineral resources: Use and exploitation, environmental effects of extracting and using
mineral resources, case studies.
iv. Food resources: World food problems, changes caused by agriculture and overgrazing,
effect of modern agriculture, fertilizer-pesticide problems, water logging, salinity, case
studies.
v. Energy resources: Growing energy needs renewable and non-renewable energy
sources, use of alternate energy sources, case studies.
vi. Land resources: Land as a resource; land degradation, man induced landslides, soil
erosion and desertification.
vii. Biodiversity and its conservation: Definition, genetic, species and ecosystem diversity,
value of biodiversity (consumptive use, productive use, social, ethical, aesthetic and
option values)
viii. Biodiversity at global, national and local levels, India as a mega diversity nation, hot
spots of biodiversity. Threats to biodiversity: habitat loss, poaching of wildlife, man
wildlife conflicts. Endangered and endemic species of India. Conservation ofbiodiversity. In-situ and Ex-situ conservation of biodiversity.
ix. Bio-geographical classification of India.
x. Role of individual in conservation of natural resources.
xi. Equitable use of resources for sustainable lifestyles.
UNITIII
3. Environmental Pollution:
i. Definition, causes, effects and control measures of:
a). Air pollution
b). Water pollution
c). Soil pollution
d). Marine pollution
e). Noise pollution
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f). Thermal pollution
g). Nuclear hazards
ii. Soil Waste Management: Causes, effects and control measures of urban and industrial
wastes.
iii. Role of an individual in prevention of pollution.
iv. Pollution case studies.
v. Disaster management: floods, earthquake, cyclone and landslides.
UNIT IV
Social issues and the environment
a) From unsustainable to sustainable development
b) Urban problems related to energy
c) Water conservation, rain water conservation, rain water harvesting, management.
d) Resettlement and rehabilitation of people: its problems and concerns. Case studies.
e) Environmental ethics: Issues and possible solutions.
f) Wasteland reclamation.
g) Consumerism and waste products.
h) Population growth, variation among nations. Family welfare program.
i) Environment and human health, human rights, value education.
j) HIV/AIDS.k) Role of information Technology in Environment and human health.
l) Case studies.
Environmental Policies and laws:
(i) Salient features of following Acts:
UNITV
a) Environment protection Act. 1986.
b) Air (prevention and control of pollution) Act. 1981.
c) Water (prevention and control of pollution) Act. 1974.
d) Wildlife (protection) Act. 1972.
e) Forest conservation Act. 1980.
f) Issues involved in enforcement of environmental legislation.
g) Public awareness.
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SECOND SEMESTER 12
PRACTICAL
BPM251
PHARMACOLOGYI [HUMAN ANATOMY & PHYSIOLOGY] Max.
Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of Exam.4 hrs
Experiments related to the following:
1. Study of human skeleton
2. Study of different systems with help of charts and models
3. Microscopic study of different tissues
4. Estimation of haemoglobin in blood. Determination of bleeding time, clotting time,
RBC count, TLC, DLC, and ESR, Blood group determination.
5. Recording of body temperature, pulse rate and blood pressure, basic understanding ofECG-PQRST waves and their significance.
6. Determination of vital capacity, experiments on spirometry.
7. Analysis of normal and abnormal urine: collection of specimen appearance,
determination of pH, sugar, proteins, urea and creatinine.
NOTE:Any other experiment(s) may be included in support of theoretical aspects of the course.
Distribution of Marks:
1. Experiments : 50 marks
2. Record : 10 marks
3. Viva voce : 10 marks
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SECOND SEMESTER 13
PRACTICAL
BPM252
PHARMACEUTICSI [GENERAL PHARMACY & DISPENSING PHARMACY]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of Exam.4 hrs
Experiments related to the following:
1. Preparation of at least 20 Pharmaceutical products such as waters, solutions, mixtures,
emulsions, infusions, sprits, tinctures and other official preparations in Indian
Pharmacopoeia.
2. Filling of hard gelatin capsules having different dosages.
3. Introduction to prescription, Latin terms commonly used types of dispensing
preparations.
4. Solid Dosages Forms: Bulk powders, incorporation of different ingredients preparationof different varieties of powders such as powders for internal use effervescent
powders, dusting powders, dentifrices etc.
.NOTE:Any other experiment(s) may be included in support of theoretical aspects of the course.
Distribution of Marks:
1. Experiments : 50 marks
2. Record : 10 marks
3. Viva voce : 10 marks
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SECOND SEMESTER 14
1. Experiments : 50 marks
2. Record : 10 marks
3. Viva voce : 10 marks
PRACTICAL
BPM- 253
PHARMACEUTICSII [COMPUTER APPLICATIONS]Max. Marks: 70; Pass Percentage: 40; Hrs/ Wk : 3; Duration of Exam : 4 Hrs
Experiments related to the following:1). Use of external commands of DOS2). Use of Ms- Word :Document creation, saving, printing, formatting, table handling and
spell checking, and letter mail and merge.
3). Use of MS- Excel:Creation, Opening, saving and printing of worksheet, Use of formulas,Creation of graphs & charts, protection.
4). Program to find the area of a rectangular.
5). Program to find the simple interest for the given values of principle, rate of interest andtime period.
6). Program to find the compound interest for the given values of principle, rate of interest
and time period.
7). Program to make a simple calculator which can perform basic arithmetic operations.8). Program to find the average of 5 integer numbers.9). Program to find the maximum of four integer numbers using if- statement.
10). Program to find the maximum of four integer numbers using conditional operator.11). Program to find the roots of a quadratic equation.
12). Program to display the following triangle using nested for loops:*
********
****************
************************
13). Program to search an integer item from a list of integer items.14). Program to sort a list of integer numbers.
15). Program to count the number of vowels and blank spaces in a given string.16). Program to find the simple and compound interests by defining two functions.
17). Program to find the area and perimeter of a square by making a single function for that.(Dont use the global variable(s))
18). Program to find the average of n integer numbers.
19). Design a menu- driven calculator program for simple arithmetic operations using switchstatement.
20). Write a program to count the number of words from a string; multiple spaces may be usedbetween two consecutive words.
NOTE:Any other experiment(s) may be included in support of theoretical aspects of the course.
Distribution of Marks:
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SECOND SEMESTER 15
PRACTICAL
BPM254
PROFESSIONAL COMMUNICATION
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 03;Duration of Exam.4 hrs
Experiments related to the following:
Objectives:
1. To expose the learners to English sound system and acquire phonetic skill and speech
rhythm.
2. To help the learners use grammar correctly.
3. To train the learners to speak English, clearly, intelligibility and effectively.
4. To equip the learners to compete for a career, and enable them to function effectively in
careers which demand good communicative skills.
Contents:
i) Nonverbal communication
- Use of hands
- Posture of shoulders
- Eye contact
- Weight of the body
- Movement of the body
ii) Applied Phonetics
- Sound of English-consonants and Vowels
- Phonemic Transcription
- Stress, Rhythm and Intonation
Remedial Grammar
- Some useful expression (introduction, greetings etc.) that are used frequently
- Common mistakes in the use of nouns, pronouns, adjectives, adverbs, prepositions and
conjunctions.
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- Use of the who and whom, much and many, still and yet, so as and so that, make and do
- Tense and their use
- Confusion of participles
- Tag Questions
Reading and Speaking skills, Listening and Speaking skills
- Presentation and addresses
- Group discussions
- Interviews
- Role playing
Reading and Writing skills, Listening and Writing skills
- Letter writing-formal and informal
- Real life social situations
- Curriculum vitae
- Agenda, notice and minutes
Distribution of Marks:
1. Total :70 Marks
2. Exercise : 30 Marks
3. Viva Voce : 30 Marks
4. Record : 10 marks
List of recommended Books (Latest editions unless specified):
1) T. Balsubramaniam.Phonetics for Indian Students, Macmillan Indian Ltd.
2) Jones, Daniel.English Pronouncing Dictionary, Cambridge Univ. Press.
3) Oxford Advanced Learners Dictionary.
4) Taylor, Grant.Conversation practice, Tata Mc grew Hills, New Delhi.
5) F.T.A. Wood.Remedial English Grammar, Macmillan India Ltd.6) Berry, Thomas Elliot. The Most Common Errors in English Usage, Tata Mc grew hills,
New Delhi.
7) N. Krishnaswamy.Modern English, Macmillan India Ltd.
8) Desmond.People Watching.
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BACHELOR OF PHARMACY
THIRD SEMESTER 1
THEORY
BPM301
PHARMACEUTICSIII [PHARMACEUTICAL MICROBIOLOGY]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1(L+T);Duration of Exam: 3 hrs
Instructions to Examiners: Two questions should be asked from each unit. Students shall be
required to attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
UNITI
1. General Microbiology: Importance of pharmaceutical microbiology. Eukaryotes &
prokaryotes (Structure of bacterial cell). Morphology and classification of bacteria, viruses,
actinomycetes, recktsieae fungi and spirochetes.2. Nutrition, cultivation, isolation and identification of bacteria and fungi.
UNITII
3. Methods of Sterilization:
a. Physical Methods:Dry heat and moist heat, design of equipment, factors governing
selection of processes. Testing efficiency of sterilizers and their applications.
b. Mechanical Methods:Bacteria proof filtration. Different devices used to retain bacteria
and mechanisms of bacterial filtration. Pore size determination and Bubble pressure
technique.
c. Chemical Methods: Treating with a bactericide, Gaseous sterilization and factors
affecting these methods.
d. Radiation Methods: Ultra violet and ionization radiations. Advantages and
disadvantages, methods of radiations production.
4. Aseptic Techniques:
Sources of contamination and methods of prevention. Water for injection and pyrogenicity.
Evaluation for particular matter, design of aseptic area, laminar flow benches.
5. Antiseptics and Disinfectants:
Definition, factors influencing disinfectants, dynamics of their action and evaluation.
Preservatives and their recommended concentrations.
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THIRD SEMESTER 2
UNIT - III
6. Immunology and Immunological Preparations:
Principles, antigens and haptens, immune system, cellular and humoral immunity,
immunological tolerance, antigen-antibody reactions and their applications. Hypersensitivity,
active and passive immunization, their preparations, standardization and storage.
7. Microbial attack and host defense, virulence and pathogenecity, primary and specific defense
mechanisms of body, infection and its transmission,
UNIT- IV
8. Microbiological Assay of antibiotics, vitamins, amino acids.
9. Sterility testing of pharmaceutical products and equipments.
10. Microbial limit test for pharmaceutical products.
UNITV
11.Fermentation and Industrial Microbiology: Fermentation and its design, Control of
different parameters in Fermentation process. Use of mutagenic agents. Isolation of mutants,
Factors influencing rate of mutation. Preparation and isolation of fermentation products with
special reference to Penicillins, Streptomycines, Tetracyclines, Alcohol, Citric acid and
Vitamin B12(Cyanocobalamin).
12. Genetic Engineering: Transformation, conjugations, transduction, protoplast fusion and gene
cloning and their applications. Development of hybridoma for monoclonal antibodies.
Books recommended (Latest editions):
1. S. J. Carter, Cooper and Gunns Tutorial Pharmacy. Sixth edition, pitman publishing co,
London.
2. M. Furbisher, Fundamentals of Microbiology, 8th
Edition, W. B. Saunders Company
Philadelphia, USA.
3. W. B. Hugo and A. D. Russell, Pharmaceutical Microbiology, Blackwell Scientific
Publications, Oxford.
4. Presscot and Donn, Industrial Microbiology, CBS, Publishers, Delhi.
5. K. K. Kieslich (Editor). Biotechnology, Vol. 6a, Verlag chemic, Basel, Switzerland.
6. M. J. Pcelzar, Reid and Chan, Microbiology, TATA Mc-Graw Hill Publishing, New Delhi.
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THIRD SEMESTER 3
7. S. J. Carter, Cooper and Gunns dispensing for pharmaceutical students, 12th Edition CBS
Publisher & Distributors, 485, Bhola Nath Nagar, Shahdara, Delhi-32.
8. A. Osal, Remingtons Pharmaceutical Sciences, Mack publishing company, Pennsylvania,
U.S.A.
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BACHELOR OF PHARMACY
THIRD SEMESTER 4
THEORY
BPM302
PHARMACEUTICSIV [PHARMACEUTICAL ENGINEERING OPERATIONS]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1 (L+T);Duration of Exam. 3 hrs
Instructions to Examiners: Two questions should be asked from each unit. Students shall be
required to attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
Unit-I
1. Stoichiometry:Unit processes, material and energy balances, molecular units, mole fraction,
tie substances, gas laws, mole volume, primary and secondary quantities, equilibrium stats rate
processes, steady and unsteady states, dimensionless equations, dimensionless formulae,dimensionless groups, different types of graphic representation
2. Fluid Flow: Types of flow, Reynolds number, Viscosity, Concept of boundary layer, basic
equations of fluid flow, manometers (simple and differential), flow meters (Venturi & Orifice),
valves (Plug cock valve, Globe valve, Gate valve), measurement of flow and pressure
(reciprocating and rotary pumps).
Unit-II
3. Heat Transfer: Concept of heat flow, applications of Fouriers law, source of heat, steam and
electricity as heating media, forced & natural Convection, surface coefficients, heat exchangers,
heat interchangers, steam pressure, solar capacity, Stefan Boltzmann equation, Kirchoffs law.
4. Evaporation:Basic concept of phase equilibrium, factors affecting evaporation, evaporators:
film evaporators, single and multiple effect evaporators.
5. Distillation: Raults law, phase diagrams, volatility, simple, steam and flash distillation,
principles of rectification, McCabe thiele method for calculations of number of theoretical plates,
Azeotropic and extractive distillation, Vacuum distillation, molecular distillation (only basic
concepts)
Unit-III
6. Drying: Moisture content and mechanism of drying, rate of drying and time of drying,
classification and types of dryers (spray dryer, drum dryer, rotating drum dryer, fluidized bed
dryer and tray dryer), sublimation and freeze drying
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BACHELOR OF PHARMACY
THIRD SEMESTER 5
7. Size reduction and size separation:Definition, objectives of size reduction, factors affecting
size reduction, laws governing energy and power requirements of mills including ball mill,
hammer mill, fluid energy mill,
8. Separation:Different techniques of size separation (sieves, sieve shakers, sedimentation tank,
cyclone separators, bag filters).
9. Filtration and centrifugation: Theory of filtration, continuous and baton filters, filter aids,
filter media, industrial filters including filter press, rotary filter, edge filter, factors affecting
filtration, principles of centrifugation, industrial centrifugal filters and centrifugal sedimenters.
Unit-IV
10. Mixing:Theory of mixing, mixing of solid-solid, solid-liquid, liquid-liquid; mixing devices:
propellers, turbines and paddles
11. Crystallization: Characteristics of crystals like purity, size, shape, geometry, habit, forms,
size and factors affecting them, solubility curves and calculation of yields, materials and heat
balances around Swenson walker crystallizer, super saturation theory and its limitation,
Nucleation mechanisms, crystal growth. Study of various types of crystallizers (tank, agitated
batch, Swenson walkers, single vacuum, circulating magma and Krystal crystalizer), caking of
crystals and its prevention.
12. Dehumidification and Humidity control:Principles of humidification, dehumidification, air
conditioning and refrigeration, hygrometric chart & measurement of humidity, equipments for
dehumidification and humidification, application of humidity measurement in pharmacy.
Unit-V
13. Material of Construction: Properties and application of the materials of construction with
special reference to stainless steel and glass, Classification & mechanism of corrosion, factors
affecting, prevention and control.
14. Industrial Hazards and safety Precautions: Mechanical, Chemical, Electrical and dust
hazards, industrial dermatitis, accident records
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BACHELOR OF PHARMACY
THIRD SEMESTER 6
Books recommended (Latest editions):
1. Mc Cable & Smith,Unit Operations of Chemical Engineering.
2. Bedger et. Al.Introduction to Chemical Engineering, McGraw Hill Co.
3. E. Lrown,Unit Operations.
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BACHELOR OF PHARMACY
THIRD SEMESTER 7
THEORY
BPM303
PHARMACOGNOSYI
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1(L+T);Duration of Exam: 3 hrs
Instructions to examiners: Two questions should be asked from each unit. Students shall be
required to attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
UNITI
1.Introduction, Development, present status and future scope of Pharmacognosy, different groups
of plants constituents.
2. Classification of Drugs: Morphological, Taxonomical, Pharmacological and chemical
classification.
3. Cultivation, collection, processing and storage of crude drugs: factors influencing
cultivation of medicinal plants. Types of soils and fertilizers of common use. Plant hormones and
their applications. Polyploidy, mutations and hybridization with special reference to the medicinal
plants.
UNITII
4. Study of carbohydrate containing drugs: Biological source, Geographical distribution,
Collection, commercial production, chemical constituents, chemical tests for identity, Substitutes,
adulterants and uses of the following:Gum Acacia,Tragacanth, Sterculia, Guargum and Plantago,
Starch, (wheat, potato, maize and rice).
5. Study of lipids and lipid containing drugs: General methods of extraction of fixed oils,
Biological sources, Chemical constituents, Tests for identity and uses of the following: Arachis
oil, Castor oil,Sesame oil, Cottonseed oil, Almond oil, Olive oil and linseed oil.
UNITIII
6. Study of drugs containing, resins and Resin combinations: Colophony,Podophyllum,
Jalap,Cannabis. Capsicum, Myrrh, Asafoetida, Balsam of Peru, Balsam of Tolu and Benzoin,
Turmeric, Ginger.
7.Study of tannins and tannin containing drugs: Hamamelis, Pale & Black catechu, Ashoka
bark, Arjuna bark, Bahera, Harad andNut meg
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BACHELOR OF PHARMACY
THIRD SEMESTER 8
UNIT- IV
8. Study of Biological sources, Cultivation, Collection, Commercial varieties, Chemical
constituents, Substitutes, Adulterants, Uses, Diagnostic macroscopic and microscopic features and
chemical tests for identity of the following groups of drugs.
a) Glycoside containing Drugs:
i.Saponin Containing Drugs:Glycyrrhiza,Senega and Dioscorea.
ii.Cardioactive Drugs:Digitalis, Squill, Strophanthus and Thievetia.
iii.Anthraquinone Cathartics:Aloe,Senna, Rhubarb and Cascara.
b) Alkaloids Containing Drugs:
i Pyridine piperidine group:Tobacco,Arica, and Lobelia.
ii.Trepan group:Belladonna, Hyoscyamus, Datura and Cocoa.
iii.Quinoline isoquinoline group:Cinchona, ipecac and opium.
iv.Indole group:Ergot, Rauwolfia, Catharanthus, Nux-vomica and physostigma.
v.Indiazole group:Pilocarpus.
vi.Steroidal group:Veratrumand kurchi bark.
vii.Alkaloid amino group:Ephedraand colchicum corm and seeds.
UNITV
9.Study of Drugs from Animal Sources:
i.Cantharides, Mylbaris and Coccus.
ii.Beeswax, Wool fat and Spermaceti.
iii.Shark liver oiland Cod liver oil.
iv. Musk v.
Honey vi.
Gelatin
Note:Italicized drugs would be dealt at primary level (whole Pharmacognosy) while other drugs
would be dealt at secondary level (only source, chemical constituents and uses).
List of books recommended (Latest editions):
1. T. E. Wallis,The Text Book of Pharmacognosy, J. & A. Churchill Lets London.
2. G. E. Treason & W. C. Evans, Pharmacognosy(12 Edition), V Bailiore Findall, London,
1983, Lea Fobiger, Philadelphia.
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BACHELOR OF PHARMACY
THIRD SEMESTER 9
3. V. E. Taylor, Lynn R. Brady, H. E. Robbers, Pharmacognosy(9thEdition), Lea & Fobiger,
Philadelphia, 1988.
4. B. P. J. C. Jackson and D. W. Snowden, Powered Vegetable drugs, Stenley Thorns Ltd,
London 1974.
5. C. K. Atlas and B. K. Kappur, Cultivation and Utilization of Medicinal plants, CSIR, India,
1982.
6. A. Krishnamurthi,The Wealth of India, Vol. I to XI, CSIR, New Delhi, 1968.
7. Iyanger,Powered crude drugs.
8. Kokate C.K, Gokhale S.B Purohit A.PPharmacognosyNirali Prakashan New Delhi.
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BACHELOR OF PHARMACY
THIRD SEMESTER 10
THEORY
BPM304
PHARMACOLOGY - II
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1(L+T);Duration of Exam: 3 hrs
Instructions to Examiners: Two questions should be asked from each unit. Students shall be
required to attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
UNITI
1. Introduction: Definition, Scope, source of drugs, dosage forms & concept of
receptors, factor modifying action.
2. ADME: Routes of drugs administration, dynamics of absorption, distribution,metabolism and excretion of drugs.
3. Molecular Pharmacology: Molecular mechanisms of drugs action, theories of
receptors, dose response relationship affinity constants, potentiation, antagonism
phenomenon.
UNITII
4. Pharmacology of Autonomic Nervous System: Automatic nerve transmission,
parasympthomimetics, parasympatholytics, sympathomimetics, sympatholytics
ganglion transmission and blockers, neuromuscular blocking agents and antispasticity
drugs.
5. Pathophysiology and drug therapy of Myasthenia gravis.
UNIT - III
6. Local anesthetics:Pharmacological study of various local anesthetic agents.
7. Autacoids:Archidonic acid metabolites, histamine, PAF, bradykinin, 5-HT.
UNIT- IV
8. Pharmacology of Central Nervous System: Synaptic transmission in the CNS.
General anesthetics, sedatives and hypnotics, Opioid analgesics.
UNITV
9. NSAIDs and drugs used in gout, antiepileptics, antiparkinsonian drugs,
psychopharmacological agent, CNS stimulants and hallucinogens.
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THIRD SEMESTER 11
10. Vitamins: Vitamin toxicity. Vitamin-drug interaction, role of vitamins in management
of adverse drug reaction
List of books recommended (Latest editions):
1. B.G. Katzung, Basic and Clinical Pharmacology Lange Medical publication, 1995.
2. A. G. Gilman, L.S. Goodmen, T. W. Rall & F. Murad,. The Pharmacological Basis
Therapytics, Macmillan Publishing Co., Ino, 1996.
3. C. R. Craige and R. F. Stitzel, Modern Pharmacology Little Brown & Co, 1994.
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BACHELOR OF PHARMACY
THIRD SEMESTER 12
PRACTICAL
BPM351
PHARMACEUTICSIII [PHARMACEUTICAL MICROBIOLOGY]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of exam: 4 hrs
Laboratory experiments related to the following:
1. Preparation and sterilization of aerobic and anaerobic media.
2. Aerobic and anaerobic cultivation of bacteria.
3. Grams staining, acid fast staining and hanging drop preparation.
4. Separation of mixed cultures and maintenance of pure cultures.
5. Microbial viable count in pharmaceutical formulations.
6. Particle count in water for injection.
7. Thermal death time studies.
8. Morphological characteristics of moulds and yeasts.
9. Turbidimetric assay of at least one drug using microbial culture.
10. Bio-Chemistry reactions:
a. Starch Hydrolysis b. Gelatin liquification c. Haemolysis of blood
d. Catalase production e. Fermentation of Carbohydrates (A/g production)
11. Phenol coefficient test for disinfectant.
12. Production of at least one product by fermentation.
13. Biological assay of tetracycline and cyanocobalamin.
14. Test for limit of alkalinity of glass.
15. Test for sterility of Pharmaceutical products as per I.P.
16. Preparation of injections of water, Dextrose, Normal saline and Oily phenol. Carrying out
quality control tests.
17. Microbial limit test for liquid and dry products.
Note:Any other experiment(s) may be included in support of the theoretical aspects of the course.
Distribution of Marks:
1. Experiment(s) : 50 marks
2. Record : 10 marks3. Viva voce : 10 marks
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BACHELOR OF PHARMACY
THIRD SEMESTER 13
PRACTICAL
BPM352
PHARMACEUTICSIV [PHARMACEUTICAL ENGINEERING OPERATIONS]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of exam: 4 hrs
Laboratory experiments related to the following:
1. (a) Determination of absolute humidity, Relative humidity, Dew point saturated-volume
and humid heat using psychromotic chart.(b) Determination of dew point using ice & water and to compare it with that obtainedusing psychrometric chart.
2. To compare the efficiencies of simple and differential manometers.
3. To perform Reynoldss experiment and to calculate Reynolds number for laminar, Criticaland turbulent flows.
4. Determination of overall efficiency of steam distillation unit (Aniline/water mixture).5. Determination of overall heat transfer coefficient (HTC) of a distillation unit.
6. To determine rate of flow using water.7. (a) Determination of rate of flow by Venturimeter / Orifice meter.
(b) Determination of coefficient of Venturimeter / Orifice meter.
8. To determine the hardness of water.9. Study of effect of insulating material on loss of heat.
10. To study the effect of factors affecting rate of filtration (pressure, thickness of cake, filteraids, viscosity)
11. To study the effect of viscosity on rate of sedimentation.
12. To determine equilibrium-moisture-content (EMC) of various substances like (a) Kaolin.(b) Talc and (c) Starch.
13. To study the effect of factors affecting rate of drying (surface area, temperature etc.)
14. Study of factors affecting rate of evaporation (temperature, surface area)15. Study to efficiency of number of balls on size reduction in Ball mill.
16. Study of characteristics of crystals, solubility curves of crystals.
Note:Any other experiment(s) may be included in support of the theoretical aspects of the course.
Distribution of Marks:1. Experiment(s) : 50 marks
2. Record : 10 marks3. Viva voce : 10 marks
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BACHELOR OF PHARMACY
THIRD SEMESTER 14
PRACTICAL
BPM353
PHARMACOGNOSYI
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of Exam:4 hrs
Laboratory experiments related to the following:
1. Taxonomic study of some medicinal plants with at least one representative of each of the
families covered in theory (organoleptic examination and physiochemical test of selected
drugs).
2. Use, Care and focusing practices of microscope. Macroscopic examination of diagnostic
principles of individual and mixtures of powered crude drugs: Senna, Stramonium,
Cinchona, Rauwolfia, Liquorice, sphere and Nux vomica.
3. Chemical tests of selected unorganized drugs.4. Test for identification of glycosides, saponins, anthraquinone, steroids, tannins.
Note:Any other experiment(s) may be included in support of the theoretical aspects of the course.
Distribution of Marks:
1. Experiment(s) : 50 marks
2. Record : 10 marks
3. Viva voce : 10 marks
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BACHELOR OF PHARMACY
THIRD SEMESTER 15
PRACTICAL
BPM354
PHARMACOLOGY - II
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3;Duration of Exam:4 hrs
Laboratory experiments related to the following:
1. Preparation of different solution for experiments, drug dilutions, common laboratory
anesthetics used in animal study, commonly used instruments in experimental
pharmacology. Some common and standard techniques.
2. To study the effect of hepatic microsomal enzyme inhibitors and induction on the
phenobarbitone sleeping time in mice.
3. Study the dose response relationship, calculation of EC50, dose ratios and affinity
constants.
4. Study of various routes of administration of drugs in mice/rate.
5. Common evaluation techniques of analgesic, anticonvulsants, drug affecting muscle
rigidity, anti-inflammatory, local anesthetics etc.
Note:Any other experiment(s) may be included in support of the theoretical aspects of the course.
Distribution of Marks:1. Experiment(s) : 50 marks
2. Record : 10 marks
3. Viva voce : 10 marks
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BACHELOR OF PHARMACY
FOURTH SEMESTER 1
THEORY
BPM401
PHARMACEUTICAL CHEMISTRYIV [PHYSICAL CHEMISTRY]
Max. Marks: 70;Pass percentage: 40;Hrs/ wk: 3+1(L+T);Duration of Exam. 3 hrs
Instructions to examiners: Two questions should be asked from each unit. Students shall be
required to attempt one question from each unit. In all, five questions shall be attempted. All
questions shall be of 14 marks each.
UNITI
1. Liquid State: Classification of physical properties, (Surface tension, Parachor, Viscosity,
Molar viscosity, Rheochor, Refractive index, Molar refractivity, Refrachor, Optical
rotation, Dipole moment only) and their use in determination of Chemical constitution.
2. Adsorption: Basic terms, Physical and Chemical adsorption, Their comparison and factors
influencing them, Types of adsorption curves, Types of Adsorption isotherms,
Freundlichs and Langmuirs adsorption isotherm equations including derivation.
Applications of adsorption in industries, Chromatography indicators.
UNITII
3. Colligative Properties: Osmotic pressure (Definitions, Experimental determination by
Berkley and Hartley method and Townsends method, Vant Hoff theory, Hypertonic,
Hypotonic and Isotonic solutions). Lowering of vapour pressure (Raoultslaw of relative
lowering of vapour pressure, Experimental determination by using Barometer, Manometer,
isoteniscope and Ostwald-Walker method). Ebullioscopy (Elevation of boiling point,
Experimental determination by Landsbergers and Cottrells method). Cryoscopy
(Depression of freezing point, Experimental determination by Beckman and Rasts
methods). Derivation of formulas to be excluded for each colligative property mentioned;
abnormal colligative properties and molecular weights, Vant Hoff factor.
UNITIII
4. Chemical Kinetics: Rate of reaction, Rate constant, Molecularity, Order and pseudo
order. Derivation of elementary zero order and 1st order kinetic equations, Examples and
Characteristics of zero order, 1st
and 2nd
order reactions. Derivation of second order kinetic
equation only when initial concentration of reactants is same, factors influencing the
reaction rate, Rate constant and order of reactions (Elementary idea). Effect of
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BACHELOR OF PHARMACY
FOURTH SEMESTER 2
Temperature, Temperature coefficient, Activation energy and Transition state. Arrhenius
equation.
5. Catalysis: Characteristics of catalyst and catalysis. Intermediate compound formation
theory, Adsorption theory and MichaelisMenten theory (Excluding the formula
derivation), characteristics of enzyme catalysis.
UNITIV
6. Thermodynamics I: Basic terms System, Surrounding, Universe, Types of systems,
Types of processes in thermodynamics, Thermodynamically reversible process, State and
non-state functions, Thermodynamic equilibrium, Thermodynamically spontaneous
processes. Concept of work done, Old and new sign conventions for heat change and work
done. Intrinsic energy, Enthalpy, Free energy and work function. Zeroth law of
thermodynamics, Definition of temperature. 1st Law of thermodynamics different
statements, Derivation of state functions like E and H from 1st
law equation,
Applications of 1st
law including its applications to biological systems, Failure of 1st
law.
7. Thermodynamics II: Different statements of 2nd Law of thermodynamics, Concept of
Entropy, Physical significance of entropy, Criteria for thermodynamically spontaneous
processes. Basic idea of 3rd
law of thermodynamics and its application in calculation of
entropy (Only elementary idea)
UNIT - V
8. Chemical Energetics: Methods to write the Thermo chemical equations, Different ways
to express the heat changes; Heat of reaction, Heat of Formation, Heat of combustion,
Heat of neutralization, Heat of fusion, Heat of vaporization, Heat of sublimation, Heat of
transition, Bond dissociation energy, Heat of atomization, Integral Heat of solution, Lattice
energy, Heat of hydration, Differential Heat of solution, Heat of dilution, Heat of
precipitation, Heat of polymerization. Hesss Law of constan