Germinal center B-cells (WT EZH2) KARPAS-422 (Y641N EZH2)

Pfeiffer (A677G EZH2) WSU-DLCL2 (Y641F EZH2)

A.

C.

B.

D.-5kb +5kb

Gene

-5kb +5kbGene

-5kb +5kbGene

-5kb +5kbGene

Supp Figure 5. H3K27me3 enrichment in various cell types across genes exhibiting up-regulation, down-regulation, or no change in SUP-B8 cells treated for 72 hours with 500 nM GSK126.